Total number of protein in "GO:0071375" GO term: 65
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADCY6 | ADCY6 | O43306 | Adenylate cyclase type 6 | chr12 | GO:0071375 | Not Cancer Driver | No | 144 | 0.123 | 147 | 17 | 0.116 | 1 |
| ADCY8 | ADCY8 | P40145 | Adenylate cyclase type 8 | chr8 | GO:0071375 | Not Cancer Driver | No | 419 | 0.335 | 215 | 38 | 0.177 | 0 |
| AGT | AGT | P01019 | Angiotensinogen | chr1 | GO:0071375 | Not Cancer Driver | No | 85 | 0.179 | 33 | 10 | 0.303 | 1 |
| APEX1_ENST00000555414 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | GO:0071375 | Not Cancer Driver | No | 34 | 0.107 | 103 | 14 | 0.136 | 0 |
| ARG1_ENST00000368087 | ARG1 | P05089 | Arginase-1 | chr6 | GO:0071375 | Not Cancer Driver | No | 41 | 0.127 | 83 | 12 | 0.145 | 9 |
| ASS1_ENST00000352480 | ASS1 | P00966 | Argininosuccinate synthase | chr9 | GO:0071375 | Not Cancer Driver | No | 65 | 0.158 | 63 | 8 | 0.127 | 86 |
| BRIP1 | BRIP1 | Q9BX63 | Fanconi anemia group J protein | chr17 | GO:0071375 | Census | Yes | 174 | 0.139 | 397 | 59 | 0.149 | 6 |
| CAV1 | CAV1 | Q03135 | Caveolin-1 | chr7 | GO:0071375 | Not Cancer Driver | No | 30 | 0.169 | 2 | 0 | 0.0 | 0 |
| CCNA2_ENST00000618014 | CCNA2 | P20248 | Cyclin-A2 | chr4 | GO:0071375 | Not Cancer Driver | No | 45 | 0.104 | 186 | 19 | 0.102 | 0 |
| CDC6 | CDC6 | Q99741 | Cell division control protein 6 homolog | chr17 | GO:0071375 | Not Cancer Driver | No | 57 | 0.102 | 170 | 15 | 0.088 | 1 |
| CPS1_ENST00000233072 | CPS1 | P31327 | Carbamoyl-phosphate synthase [ammonia], mitochondrial | chr2 | GO:0071375 | Not Cancer Driver | No | 368 | 0.245 | 73 | 22 | 0.301 | 140 |
| CRHBP | CRHBP | P24387 | Corticotropin-releasing factor-binding protein | chr5 | GO:0071375 | Not Cancer Driver | No | 61 | 0.189 | 0 | 0 | 0.0 | 0 |
| CRHR1 | CRHR1 | P34998 | Corticotropin-releasing factor receptor 1 | chr17 | GO:0071375 | Not Cancer Driver | No | 75 | 0.169 | 0 | 0 | 0.0 | 0 |
| CRHR2_ENST00000471646 | CRHR2 | Q13324 | Corticotropin-releasing factor receptor 2 | chr7 | GO:0071375 | Not Cancer Driver | No | 79 | 0.192 | 0 | 0 | 0.0 | 0 |
| CRK | CRK | P46108 | Adapter molecule crk | chr17 | GO:0071375 | Not Cancer Driver | No | 30 | 0.099 | 197 | 23 | 0.117 | 0 |
| CSK_ENST00000439220 | CSK | P41240 | Tyrosine-protein kinase CSK | chr15 | GO:0071375 | Not Cancer Driver | No | 41 | 0.091 | 18 | 1 | 0.056 | 0 |
| CYBA | CYBA | P13498 | Cytochrome b-245 light chain | chr16 | GO:0071375 | Not Cancer Driver | No | 26 | 0.133 | 66 | 2 | 0.03 | 12 |
| CYP11A1 | CYP11A1 | P05108 | Cholesterol side-chain cleavage enzyme, mitochondrial | chr15 | GO:0071375 | Not Cancer Driver | No | 92 | 0.177 | 27 | 6 | 0.222 | 6 |
| CYP11B1 | CYP11B1 | P15538 | Cytochrome P450 11B1, mitochondrial | chr8 | GO:0071375 | Not Cancer Driver | No | 177 | 0.352 | 7 | 1 | 0.143 | 50 |
| CYP11B2 | CYP11B2 | P19099 | Cytochrome P450 11B2, mitochondrial | chr8 | GO:0071375 | Not Cancer Driver | No | 148 | 0.294 | 6 | 0 | 0.0 | 6 |
| CYP1B1 | CYP1B1 | Q16678 | Cytochrome P450 1B1 | chr2 | GO:0071375 | Not Cancer Driver | No | 61 | 0.112 | 31 | 3 | 0.097 | 40 |
| CYSLTR2_ENST00000614739 | CYSLTR2 | Q9NS75 | Cysteinyl leukotriene receptor 2 | chr13 | GO:0071375 | Census, Compendium | Yes | 64 | 0.185 | 0 | 0 | 0.0 | 0 |
| EDN1 | EDN1 | P05305 | Endothelin-1 | chr6 | GO:0071375 | Not Cancer Driver | No | 37 | 0.175 | 97 | 20 | 0.206 | 3 |
| EDNRA | EDNRA | P25101 | Endothelin-1 receptor | chr4 | GO:0071375 | Not Cancer Driver | No | 62 | 0.145 | 21 | 6 | 0.286 | 2 |
| FBN1 | FBN1 | P35555 | Fibrillin-1 | chr15 | GO:0071375 | Not Cancer Driver | No | 466 | 0.162 | 110 | 16 | 0.145 | 360 |
| FGF21 | FGF21 | Q9NSA1 | Fibroblast growth factor 21 | chr19 | GO:0071375 | Not Cancer Driver | No | 37 | 0.177 | 109 | 24 | 0.22 | 0 |
| GCGR | GCGR | P47871 | Glucagon receptor | chr17 | GO:0071375 | Not Cancer Driver | No | 16 | 0.034 | 56 | 2 | 0.036 | 4 |
| GHSR | GHSR | Q92847 | Growth hormone secretagogue receptor type 1 | chr3 | GO:0071375 | Not Cancer Driver | No | 85 | 0.232 | 4 | 0 | 0.0 | 2 |
| GJB2_ENST00000382848 | GJB2 | P29033 | Gap junction beta-2 protein | chr13 | GO:0071375 | Not Cancer Driver | No | 34 | 0.15 | 0 | 0 | 0.0 | 46 |
| GLP1R | GLP1R | P43220 | Glucagon-like peptide 1 receptor | chr6 | GO:0071375 | Not Cancer Driver | No | 75 | 0.162 | 18 | 2 | 0.111 | 0 |
| GLP2R | GLP2R | O95838 | Glucagon-like peptide 2 receptor | chr17 | GO:0071375 | Not Cancer Driver | No | 124 | 0.224 | 63 | 14 | 0.222 | 0 |
| GNRHR | GNRHR | P30968 | Gonadotropin-releasing hormone receptor | chr4 | GO:0071375 | Not Cancer Driver | No | 40 | 0.122 | 15 | 1 | 0.067 | 14 |
| GPER1 | GPER1 | Q99527 | G-protein coupled estrogen receptor 1 | chr7 | GO:0071375 | Not Cancer Driver | No | 65 | 0.173 | 13 | 5 | 0.385 | 0 |
| GPR173 | GPR173 | Q9NS66 | Probable G-protein coupled receptor 173 | chrX | GO:0071375 | Not Cancer Driver | No | 57 | 0.153 | 12 | 0 | 0.0 | 0 |
| HSF1 | HSF1 | Q00613 | Heat shock factor protein 1 | chr8 | GO:0071375 | Not Cancer Driver | No | 59 | 0.112 | 335 | 37 | 0.11 | 0 |
| IGF1R | IGF1R | P08069 | Insulin-like growth factor 1 receptor | chr15 | GO:0071375 | Not Cancer Driver | No | 183 | 0.134 | 265 | 37 | 0.14 | 6 |
| LHCGR | LHCGR | P22888 | Lutropin-choriogonadotropic hormone receptor | chr2 | GO:0071375 | Not Cancer Driver | No | 181 | 0.259 | 12 | 8 | 0.667 | 25 |
| MAP1B | MAP1B | P46821 | Microtubule-associated protein 1B | chr5 | GO:0071375 | Not Cancer Driver | No | 332 | 0.135 | 1947 | 278 | 0.143 | 0 |
| MAX | MAX | P61244 | Protein max | chr14 | GO:0071375 | Census, Compendium | Yes | 45 | 0.281 | 160 | 45 | 0.281 | 9 |
| MEN1 | MEN1 | O00255 | Menin | chr11 | GO:0071375 | Census, Compendium | Yes | 73 | 0.119 | 228 | 15 | 0.066 | 90 |
| MGARP | MGARP | Q8TDB4 | Protein MGARP | chr4 | GO:0071375 | Not Cancer Driver | No | 25 | 0.104 | 207 | 22 | 0.106 | 0 |
| MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | GO:0071375 | Census, Compendium | Yes | 80 | 0.182 | 299 | 46 | 0.154 | 0 |
| NFE2L2 | NFE2L2 | Q16236 | Nuclear factor erythroid 2-related factor 2 | chr2 | GO:0071375 | Census, Compendium | Yes | 228 | 0.377 | 402 | 62 | 0.154 | 4 |
| NFKB1_ENST00000505458 | NFKB1 | P19838 | Nuclear factor NF-kappa-B p105 subunit | chr4 | GO:0071375 | Not Cancer Driver | No | 104 | 0.107 | 344 | 38 | 0.11 | 0 |
| NKX6-1 | NKX6-1 | P78426 | Homeobox protein Nkx-6.1 | chr4 | GO:0071375 | Not Cancer Driver | No | 38 | 0.104 | 325 | 34 | 0.105 | 0 |
| NR4A1_ENST00000394825 | NR4A1 | P22736 | Nuclear receptor subfamily 4 group A member 1 | chr12 | GO:0071375 | Not Cancer Driver | No | 62 | 0.104 | 252 | 24 | 0.095 | 0 |
| NR4A2_ENST00000409572 | NR4A2 | P43354 | Nuclear receptor subfamily 4 group A member 2 | chr2 | GO:0071375 | Not Cancer Driver | No | 110 | 0.184 | 261 | 38 | 0.146 | 0 |
| NR4A3_ENST00000395097 | NR4A3 | Q92570 | Nuclear receptor subfamily 4 group A member 3 | chr9 | GO:0071375 | Census | Yes | 83 | 0.133 | 298 | 37 | 0.124 | 0 |
| PCK1 | PCK1 | P35558 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | chr20 | GO:0071375 | Not Cancer Driver | No | 142 | 0.228 | 110 | 28 | 0.255 | 1 |
| PLAT | PLAT | P00750 | Tissue-type plasminogen activator | chr8 | GO:0071375 | Not Cancer Driver | No | 89 | 0.158 | 15 | 2 | 0.133 | 0 |
| PLCB1 | PLCB1 | Q9NQ66 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 | chr20 | GO:0071375 | Not Cancer Driver | No | 313 | 0.257 | 481 | 104 | 0.216 | 0 |
| POR | POR | P16435 | NADPH--cytochrome P450 reductase | chr7 | GO:0071375 | Not Cancer Driver | No | 62 | 0.092 | 93 | 4 | 0.043 | 9 |
| PRKCD_ENST00000330452 | PRKCD | Q05655 | Protein kinase C delta type | chr3 | GO:0071375 | Compendium | Yes | 79 | 0.117 | 43 | 9 | 0.209 | 0 |
| RANGAP1_ENST00000356244 | RANGAP1 | P46060 | Ran GTPase-activating protein 1 | chr22 | GO:0071375 | Not Cancer Driver | No | 65 | 0.111 | 159 | 17 | 0.107 | 0 |
| RELA | RELA | Q04206 | Transcription factor p65 | chr11 | GO:0071375 | Compendium | Yes | 75 | 0.136 | 400 | 48 | 0.12 | 0 |
| SLC25A33 | SLC25A33 | Q9BSK2 | Solute carrier family 25 member 33 | chr1 | GO:0071375 | Not Cancer Driver | No | 23 | 0.072 | 4 | 0 | 0.0 | 0 |
| SLC30A10 | SLC30A10 | Q6XR72 | Zinc transporter 10 | chr1 | GO:0071375 | Not Cancer Driver | No | 68 | 0.14 | 61 | 10 | 0.164 | 2 |
| SPINK1 | SPINK1 | P00995 | Serine protease inhibitor Kazal-type 1 | chr5 | GO:0071375 | Not Cancer Driver | No | 14 | 0.177 | 0 | 0 | 0.0 | 3 |
| SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0071375 | Census | Yes | 53 | 0.099 | 130 | 11 | 0.085 | 1 |
| SYAP1 | SYAP1 | Q96A49 | Synapse-associated protein 1 | chrX | GO:0071375 | Not Cancer Driver | No | 31 | 0.088 | 221 | 22 | 0.1 | 0 |
| TSHR | TSHR | P16473 | Thyrotropin receptor | chr14 | GO:0071375 | Census | Yes | 128 | 0.168 | 38 | 9 | 0.237 | 39 |
| UMODL1_ENST00000408910 | UMODL1 | Q5DID0 | Uromodulin-like 1 | chr21 | GO:0071375 | Not Cancer Driver | No | 191 | 0.145 | 249 | 29 | 0.116 | 0 |
| WNT1 | WNT1 | P04628 | Proto-oncogene Wnt-1 | chr12 | GO:0071375 | Not Cancer Driver | No | 29 | 0.078 | 25 | 0 | 0.0 | 8 |
| XBP1 | XBP1 | P17861 | X-box-binding protein 1 | chr22 | GO:0071375 | Not Cancer Driver | No | 19 | 0.073 | 169 | 9 | 0.053 | 0 |
| ZFP36L1 | ZFP36L1 | Q07352 | mRNA decay activator protein ZFP36L1 | chr14 | GO:0071375 | Compendium | Yes | 57 | 0.169 | 212 | 30 | 0.142 | 0 |