Filter in search result
Please select a valid state.

Total number of protein in "GO:0071363" GO term:  194

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACAP2 ACAP2 Q15057 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 chr3 GO:0071363 Not Cancer Driver No 97 0.125 287 40 0.139 0
ACVR1B_ENST00000257963 ACVR1B P36896 Activin receptor type-1B chr12 GO:0071363 Census Yes 114 0.226 0 0 0.0 0
ACVR1C ACVR1C Q8NER5 Activin receptor type-1C chr2 GO:0071363 Not Cancer Driver No 90 0.183 3 1 0.333 0
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0071363 Census, Compendium Yes 78 0.153 21 8 0.381 8
ACVR2A_ENST00000404590 ACVR2A P27037 Activin receptor type-2A chr2 GO:0071363 Census, Compendium Yes 98 0.191 56 6 0.107 0
ACVR2B ACVR2B Q13705 Activin receptor type-2B chr3 GO:0071363 Not Cancer Driver No 83 0.162 70 14 0.2 2
ACVRL1 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0071363 Not Cancer Driver No 93 0.185 60 11 0.183 82
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0071363 Census, Compendium Yes 108 0.225 158 24 0.152 4
AMHR2 AMHR2 Q16671 Anti-Muellerian hormone type-2 receptor chr12 GO:0071363 Not Cancer Driver No 77 0.134 117 7 0.06 8
ANGPT2 ANGPT2 O15123 Angiopoietin-2 chr8 GO:0071363 Not Cancer Driver No 63 0.127 96 10 0.104 1
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0071363 Not Cancer Driver No 59 0.171 61 12 0.197 0
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0071363 Not Cancer Driver No 128 0.166 418 71 0.17 17
APPL1 APPL1 Q9UKG1 DCC-interacting protein 13-alpha chr3 GO:0071363 Not Cancer Driver No 67 0.094 292 31 0.106 1
APPL2_ENST00000258530 APPL2 Q8NEU8 DCC-interacting protein 13-beta chr12 GO:0071363 Not Cancer Driver No 70 0.105 149 14 0.094 0
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 GO:0071363 Not Cancer Driver No 18 0.103 5 0 0.0 0
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX GO:0071363 Not Cancer Driver No 228 0.152 171 46 0.269 52
BAG4 BAG4 O95429 BAG family molecular chaperone regulator 4 chr8 GO:0071363 Not Cancer Driver No 55 0.12 402 49 0.122 0
BAIAP2 BAIAP2 Q9UQB8 Brain-specific angiogenesis inhibitor 1-associated protein 2 chr17 GO:0071363 Not Cancer Driver No 85 0.154 330 52 0.158 0
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 GO:0071363 Not Cancer Driver No 108 0.124 677 75 0.111 0
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0071363 Not Cancer Driver No 45 0.1 190 19 0.1 0
BGLAP BGLAP P02818 Osteocalcin chr1 GO:0071363 Not Cancer Driver No 13 0.13 21 2 0.095 0
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0071363 Census, Compendium Yes 66 0.124 21 0 0.0 8
BMPR1B_ENST00000394931 BMPR1B O00238 Bone morphogenetic protein receptor type-1B chr4 GO:0071363 Not Cancer Driver No 84 0.167 64 12 0.188 5
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0071363 Compendium Yes 141 0.136 601 70 0.116 19
CASR_ENST00000638421 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0071363 Not Cancer Driver No 304 0.282 189 60 0.317 108
CAT CAT P04040 Catalase chr11 GO:0071363 Not Cancer Driver No 70 0.133 176 18 0.102 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0071363 Census, Compendium Yes 115 0.127 512 56 0.109 4
CCL2 CCL2 P13500 C-C motif chemokine 2 chr17 GO:0071363 Not Cancer Driver No 20 0.202 15 5 0.333 0
CCNA2_ENST00000618014 CCNA2 P20248 Cyclin-A2 chr4 GO:0071363 Not Cancer Driver No 45 0.104 186 19 0.102 0
CD44 CD44 P16070 CD44 antigen chr11 GO:0071363 Not Cancer Driver No 75 0.101 542 60 0.111 0
CFLAR CFLAR O15519 CASP8 and FADD-like apoptosis regulator chr2 GO:0071363 Not Cancer Driver No 40 0.083 44 2 0.045 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0071363 Not Cancer Driver No 24 0.126 6 1 0.167 0
COL1A1 COL1A1 P02452 Collagen alpha-1(I) chain chr17 GO:0071363 Census, Compendium Yes 247 0.169 1212 214 0.177 148
CORO1B CORO1B Q9BR76 Coronin-1B chr11 GO:0071363 Not Cancer Driver No 41 0.084 138 10 0.072 0
CPNE3 CPNE3 O75131 Copine-3 chr8 GO:0071363 Not Cancer Driver No 79 0.147 33 5 0.152 0
CPS1_ENST00000233072 CPS1 P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial chr2 GO:0071363 Not Cancer Driver No 368 0.245 73 22 0.301 140
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 GO:0071363 Census Yes 25 0.076 277 23 0.083 0
CRK CRK P46108 Adapter molecule crk chr17 GO:0071363 Not Cancer Driver No 30 0.099 197 23 0.117 0
CSNK1D CSNK1D P48730 Casein kinase I isoform delta chr17 GO:0071363 Not Cancer Driver No 59 0.142 132 16 0.121 2
CSTF2_ENST00000372972 CSTF2 P33240 Cleavage stimulation factor subunit 2 chrX GO:0071363 Not Cancer Driver No 85 0.147 484 72 0.149 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0071363 Census, Compendium Yes 415 0.531 288 301 1.045 14
CXCL8 CXCL8 P10145 Interleukin-8 chr4 GO:0071363 Not Cancer Driver No 17 0.172 0 0 0.0 0
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0071363 Not Cancer Driver No 144 0.187 680 125 0.184 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0071363 Not Cancer Driver No 131 0.11 681 68 0.1 0
DDC DDC P20711 Aromatic-L-amino-acid decarboxylase chr7 GO:0071363 Not Cancer Driver No 98 0.204 5 0 0.0 9
DLL4 DLL4 Q9NR61 Delta-like protein 4 chr15 GO:0071363 Not Cancer Driver No 75 0.109 73 15 0.205 7
DSTYK DSTYK Q6XUX3 Dual serine/threonine and tyrosine protein kinase chr1 GO:0071363 Not Cancer Driver No 112 0.121 112 4 0.036 2
DTYMK DTYMK P23919 Thymidylate kinase chr2 GO:0071363 Not Cancer Driver No 10 0.047 0 0 0.0 0
DUSP22_ENST00000344450 DUSP22 Q9NRW4 Dual specificity protein phosphatase 22 chr6 GO:0071363 Not Cancer Driver No 84 0.457 0 0 0.0 0
DUSP3 DUSP3 P51452 Dual specificity protein phosphatase 3 chr17 GO:0071363 Not Cancer Driver No 21 0.114 4 1 0.25 0
DYNC1LI2 DYNC1LI2 O43237 Cytoplasmic dynein 1 light intermediate chain 2 chr16 GO:0071363 Not Cancer Driver No 43 0.087 211 14 0.066 0
E2F1 E2F1 Q01094 Transcription factor E2F1 chr20 GO:0071363 Not Cancer Driver No 49 0.112 272 23 0.085 0
EEF1A1 EEF1A1 P68104 Elongation factor 1-alpha 1 chr6 GO:0071363 Not Cancer Driver No 109 0.236 100 14 0.14 0
EEF2K EEF2K O00418 Eukaryotic elongation factor 2 kinase chr16 GO:0071363 Not Cancer Driver No 104 0.143 311 39 0.125 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0071363 Census, Compendium Yes 444 0.367 223 35 0.157 1
EGR3 EGR3 Q06889 Early growth response protein 3 chr8 GO:0071363 Not Cancer Driver No 60 0.155 252 46 0.183 0
EHD1_ENST00000359393 EHD1 Q9H4M9 EH domain-containing protein 1 chr11 GO:0071363 Not Cancer Driver No 72 0.135 90 12 0.133 0
EHD4 EHD4 Q9H223 EH domain-containing protein 4 chr15 GO:0071363 Not Cancer Driver No 54 0.1 98 7 0.071 0
EIF4A3 EIF4A3 P38919 Eukaryotic initiation factor 4A-III chr17 GO:0071363 Not Cancer Driver No 50 0.122 57 6 0.105 1
ELAVL4_ENST00000371821 ELAVL4 P26378 ELAV-like protein 4 chr1 GO:0071363 Not Cancer Driver No 118 0.306 117 34 0.291 0
EMD EMD P50402 Emerin chrX GO:0071363 Not Cancer Driver No 42 0.165 160 28 0.175 4
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0071363 Census, Compendium Yes 275 0.219 314 41 0.131 1
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 GO:0071363 Census, Compendium Yes 428 0.327 323 116 0.359 2
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0071363 Not Cancer Driver No 125 0.128 250 28 0.112 0
ERRFI1 ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 chr1 GO:0071363 Not Cancer Driver No 55 0.119 297 37 0.125 0
EXT2_ENST00000533608 EXT2 Q93063 Exostosin-2 chr11 GO:0071363 Census, Compendium Yes 93 0.13 12 1 0.083 9
FEZ1 FEZ1 Q99689 Fasciculation and elongation protein zeta-1 chr11 GO:0071363 Not Cancer Driver No 66 0.168 277 49 0.177 0
FLT1 FLT1 P17948 Vascular endothelial growth factor receptor 1 chr13 GO:0071363 Not Cancer Driver No 299 0.223 103 20 0.194 0
FLT4 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 GO:0071363 Census, Compendium Yes 253 0.186 259 41 0.158 13
FOXC1_ENST00000645831 FOXC1 Q12948 Forkhead box protein C1 chr6 GO:0071363 Not Cancer Driver No 33 0.06 411 24 0.058 32
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0071363 Census, Compendium Yes 70 0.104 595 68 0.114 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0071363 Not Cancer Driver No 92 0.171 70 13 0.186 0
GAREM1 GAREM1 Q9H706 GRB2-associated and regulator of MAPK protein 1 chr18 GO:0071363 Not Cancer Driver No 128 0.146 408 50 0.123 0
GAS1 GAS1 P54826 Growth arrest-specific protein 1 chr9 GO:0071363 Not Cancer Driver No 13 0.038 82 4 0.049 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0071363 Not Cancer Driver No 82 0.121 42 6 0.143 0
GCLC GCLC P48506 Glutamate--cysteine ligase catalytic subunit chr6 GO:0071363 Not Cancer Driver No 73 0.115 167 18 0.108 3
GCLM GCLM P48507 Glutamate--cysteine ligase regulatory subunit chr1 GO:0071363 Not Cancer Driver No 32 0.117 31 3 0.097 0
HAS1 HAS1 Q92839 Hyaluronan synthase 1 chr19 GO:0071363 Not Cancer Driver No 115 0.199 9 0 0.0 0
HAS2 HAS2 Q92819 Hyaluronan synthase 2 chr8 GO:0071363 Not Cancer Driver No 100 0.181 17 7 0.412 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 GO:0071363 Not Cancer Driver No 47 0.098 135 10 0.074 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0071363 Not Cancer Driver No 37 0.132 226 32 0.142 0
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0071363 Compendium Yes 233 0.32 43 16 0.372 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 GO:0071363 Not Cancer Driver No 73 0.112 282 35 0.124 0
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 GO:0071363 Not Cancer Driver No 10 0.049 118 8 0.068 20
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 GO:0071363 Compendium Yes 44 0.096 127 9 0.071 2
HYAL1_ENST00000395144 HYAL1 Q12794 Hyaluronidase-1 chr3 GO:0071363 Not Cancer Driver No 47 0.108 9 0 0.0 1
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:0071363 Not Cancer Driver No 52 0.11 8 1 0.125 0
IBSP IBSP P21815 Bone sialoprotein 2 chr4 GO:0071363 Not Cancer Driver No 79 0.249 274 69 0.252 0
ID1 ID1 P41134 DNA-binding protein inhibitor ID-1 chr20 GO:0071363 Not Cancer Driver No 20 0.129 17 6 0.353 0
IL10 IL10 P22301 Interleukin-10 chr1 GO:0071363 Not Cancer Driver No 19 0.107 23 1 0.043 0
INPP5K INPP5K Q9BT40 Inositol polyphosphate 5-phosphatase K chr17 GO:0071363 Not Cancer Driver No 42 0.094 34 2 0.059 7
INSR INSR P06213 Insulin receptor chr19 GO:0071363 Not Cancer Driver No 190 0.137 280 57 0.204 64
IQGAP1 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 GO:0071363 Not Cancer Driver No 183 0.11 351 35 0.1 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0071363 Not Cancer Driver No 26 0.13 58 11 0.19 0
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 GO:0071363 Not Cancer Driver No 88 0.105 251 17 0.068 0
KDM5B_ENST00000367265 KDM5B Q9UGL1 Lysine-specific demethylase 5B chr1 GO:0071363 Not Cancer Driver No 219 0.142 388 58 0.149 0
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0071363 Census, Compendium Yes 357 0.263 275 55 0.2 2
KIDINS220 KIDINS220 Q9ULH0 Kinase D-interacting substrate of 220 kDa chr2 GO:0071363 Not Cancer Driver No 245 0.138 683 113 0.165 0
KNSTRN KNSTRN Q9Y448 Small kinetochore-associated protein chr15 GO:0071363 Census Yes 75 0.237 246 67 0.272 0
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 GO:0071363 Not Cancer Driver No 57 0.132 112 19 0.17 0
LRP2 LRP2 P98164 Low-density lipoprotein receptor-related protein 2 chr2 GO:0071363 Not Cancer Driver No 998 0.214 209 40 0.191 1
LRP8 LRP8 Q14114 Low-density lipoprotein receptor-related protein 8 chr1 GO:0071363 Not Cancer Driver No 94 0.098 190 24 0.126 0
MAGI2 MAGI2 Q86UL8 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 chr7 GO:0071363 Not Cancer Driver No 305 0.21 1086 201 0.185 0
MAP1B MAP1B P46821 Microtubule-associated protein 1B chr5 GO:0071363 Not Cancer Driver No 332 0.135 1947 278 0.143 0
MAP2K3 MAP2K3 P46734 Dual specificity mitogen-activated protein kinase kinase 3 chr17 GO:0071363 Not Cancer Driver No 104 0.3 75 27 0.36 0
MAP2K5 MAP2K5 Q13163 Dual specificity mitogen-activated protein kinase kinase 5 chr15 GO:0071363 Not Cancer Driver No 40 0.089 85 10 0.118 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0071363 Not Cancer Driver No 39 0.108 25 1 0.04 0
MAPK7 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 GO:0071363 Not Cancer Driver No 92 0.113 490 50 0.102 0
MAPKAPK2 MAPKAPK2 P49137 MAP kinase-activated protein kinase 2 chr1 GO:0071363 Not Cancer Driver No 43 0.107 92 5 0.054 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0071363 Not Cancer Driver No 128 0.169 750 126 0.168 18
MARS MARS1 P56192 Methionine--tRNA ligase, cytoplasmic chr12 GO:0071363 Not Cancer Driver No 91 0.101 151 16 0.106 8
MCM7 MCM7 P33993 DNA replication licensing factor MCM7 chr7 GO:0071363 Not Cancer Driver No 101 0.14 128 22 0.172 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0071363 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MT1G MT1G P13640 Metallothionein-1G chr16 GO:0071363 Not Cancer Driver No 9 0.145 0 0 0.0 0
MTSS1L MTSS2 Q765P7 Protein MTSS 2 chr16 GO:0071363 Not Cancer Driver No 62 0.083 582 49 0.084 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0071363 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYOG MYOG P15173 Myogenin chr1 GO:0071363 Not Cancer Driver No 36 0.161 132 20 0.152 0
NCL NCL P19338 Nucleolin chr2 GO:0071363 Not Cancer Driver No 85 0.12 569 68 0.12 0
NDNF NDNF Q8TB73 Protein NDNF chr4 GO:0071363 Not Cancer Driver No 125 0.22 129 29 0.225 1
NOS1_ENST00000317775 NOS1 P29475 Nitric oxide synthase, brain chr12 GO:0071363 Not Cancer Driver No 405 0.282 342 99 0.289 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0071363 Census, Compendium Yes 363 0.142 686 87 0.127 3
NR4A1_ENST00000394825 NR4A1 P22736 Nuclear receptor subfamily 4 group A member 1 chr12 GO:0071363 Not Cancer Driver No 62 0.104 252 24 0.095 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0071363 Compendium Yes 146 0.158 211 31 0.147 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0071363 Census, Compendium Yes 168 0.211 57 8 0.14 25
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:0071363 Not Cancer Driver No 155 0.189 117 18 0.154 1
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0071363 Census, Compendium Yes 249 0.297 57 21 0.368 0
OPRD1 OPRD1 P41143 Delta-type opioid receptor chr1 GO:0071363 Not Cancer Driver No 91 0.245 30 3 0.1 0
PAX2_ENST00000428433 PAX2 Q02962 Paired box protein Pax-2 chr10 GO:0071363 Not Cancer Driver No 62 0.149 296 48 0.162 23
PAX9 PAX9 P55771 Paired box protein Pax-9 chr14 GO:0071363 Not Cancer Driver No 52 0.152 198 32 0.162 1
PDE8A_ENST00000394553 PDE8A O60658 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A chr15 GO:0071363 Not Cancer Driver No 78 0.094 187 17 0.091 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0071363 Census Yes 37 0.154 99 22 0.222 2
PDGFD PDGFD Q9GZP0 Platelet-derived growth factor D chr11 GO:0071363 Not Cancer Driver No 85 0.23 37 13 0.351 0
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0071363 Census, Compendium Yes 164 0.148 231 44 0.19 7
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0071363 Not Cancer Driver No 33 0.059 121 12 0.099 0
PITX3_ENST00000539804 PITX3 O75364 Pituitary homeobox 3 chr10 GO:0071363 Not Cancer Driver No 24 0.079 155 12 0.077 1
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 GO:0071363 Census, Compendium Yes 158 0.122 186 21 0.113 0
PLK5 PLK5 Q496M5 Inactive serine/threonine-protein kinase PLK5 chr19 GO:0071363 Not Cancer Driver No 8 0.024 215 4 0.019 0
PPP1R9B PPP1R9B Q96SB3 Neurabin-2 chr17 GO:0071363 Not Cancer Driver No 47 0.058 695 35 0.05 0
PPP2R5B PPP2R5B Q15173 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform chr11 GO:0071363 Not Cancer Driver No 79 0.159 119 9 0.076 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 GO:0071363 Census Yes 201 0.22 189 33 0.175 2
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0071363 Compendium Yes 118 0.134 246 34 0.138 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0071363 Census, Compendium Yes 129 0.218 260 38 0.146 60
PTPN12 PTPN12 Q05209 Tyrosine-protein phosphatase non-receptor type 12 chr7 GO:0071363 Not Cancer Driver No 102 0.131 516 60 0.116 0
RAB35 RAB35 Q15286 Ras-related protein Rab-35 chr12 GO:0071363 Not Cancer Driver No 25 0.124 25 2 0.08 0
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:0071363 Not Cancer Driver No 34 0.107 13 0 0.0 0
RAMP2 RAMP2 O60895 Receptor activity-modifying protein 2 chr17 GO:0071363 Not Cancer Driver No 18 0.103 34 6 0.176 0
RAP1A_ENST00000356415 RAP1A P62834 Ras-related protein Rap-1A chr1 GO:0071363 Not Cancer Driver No 27 0.147 5 0 0.0 0
RAP1GAP_ENST00000374765 RAP1GAP P47736 Rap1 GTPase-activating protein 1 chr1 GO:0071363 Not Cancer Driver No 81 0.122 313 39 0.125 0
RAPGEF1_ENST00000372189 RAPGEF1 Q13905 Rap guanine nucleotide exchange factor 1 chr9 GO:0071363 Not Cancer Driver No 158 0.147 589 87 0.148 0
RAPGEF2 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 GO:0071363 Not Cancer Driver No 216 0.144 803 116 0.144 0
RDX_ENST00000343115 RDX P35241 Radixin chr11 GO:0071363 Not Cancer Driver No 71 0.122 297 37 0.125 1
RELA RELA Q04206 Transcription factor p65 chr11 GO:0071363 Compendium Yes 75 0.136 400 48 0.12 0
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:0071363 Compendium Yes 82 0.122 277 39 0.141 4
RPS6KB1 RPS6KB1 P23443 Ribosomal protein S6 kinase beta-1 chr17 GO:0071363 Not Cancer Driver No 45 0.086 226 26 0.115 0
SEMA6A_ENST00000510263 SEMA6A Q9H2E6 Semaphorin-6A chr5 GO:0071363 Not Cancer Driver No 136 0.132 456 72 0.158 0
SETX SETX Q7Z333 Probable helicase senataxin chr9 GO:0071363 Not Cancer Driver No 342 0.128 1240 156 0.126 20
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0071363 Not Cancer Driver No 40 0.127 39 7 0.179 0
SH3GL2 SH3GL2 Q99962 Endophilin-A1 chr9 GO:0071363 Not Cancer Driver No 76 0.216 214 50 0.234 0
SHC1_ENST00000368445 SHC1 P29353 SHC-transforming protein 1 chr1 GO:0071363 Not Cancer Driver No 84 0.144 397 58 0.146 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0071363 Not Cancer Driver No 56 0.144 85 17 0.2 0
SNAI2_ENST00000020945 SNAI2 O43623 Zinc finger protein SNAI2 chr8 GO:0071363 Not Cancer Driver No 52 0.194 52 9 0.173 0
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0071363 Compendium Yes 86 0.169 495 82 0.166 18
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0071363 Not Cancer Driver No 47 0.122 25 2 0.08 0
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 GO:0071363 Not Cancer Driver No 46 0.146 169 29 0.172 1
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0071363 Census Yes 53 0.099 130 11 0.085 1
SRD5A1 SRD5A1 P18405 3-oxo-5-alpha-steroid 4-dehydrogenase 1 chr5 GO:0071363 Not Cancer Driver No 35 0.135 0 0 0.0 0
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 GO:0071363 Census, Compendium Yes 93 0.118 144 19 0.132 5
STMN2_ENST00000220876 STMN2 Q93045 Stathmin-2 chr8 GO:0071363 Not Cancer Driver No 34 0.19 122 23 0.189 0
SYAP1 SYAP1 Q96A49 Synapse-associated protein 1 chrX GO:0071363 Not Cancer Driver No 31 0.088 221 22 0.1 0
TAC1 TAC1 P20366 Protachykinin-1 chr7 GO:0071363 Not Cancer Driver No 31 0.24 18 4 0.222 0
TBX1_ENST00000329705 TBX1 O43435 T-box transcription factor TBX1 chr22 GO:0071363 Not Cancer Driver No 35 0.088 197 12 0.061 4
TDGF1 TDGF1 P13385 Teratocarcinoma-derived growth factor 1 chr3 GO:0071363 Not Cancer Driver No 39 0.207 25 2 0.08 0
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0071363 Not Cancer Driver No 86 0.171 23 3 0.13 15
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0071363 Census, Compendium Yes 106 0.187 60 16 0.267 25
TH TH P07101 Tyrosine 3-monooxygenase chr11 GO:0071363 Not Cancer Driver No 61 0.116 149 21 0.141 38
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0071363 Not Cancer Driver No 188 0.161 320 58 0.181 0
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0071363 Not Cancer Driver No 292 0.348 0 0 0.0 0
TMEM108 TMEM108 Q6UXF1 Transmembrane protein 108 chr3 GO:0071363 Not Cancer Driver No 101 0.176 458 89 0.194 0
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 GO:0071363 Not Cancer Driver No 48 0.104 229 28 0.122 0
TRPV1_ENST00000399756 TRPV1 Q8NER1 Transient receptor potential cation channel subfamily V member 1 chr17 GO:0071363 Not Cancer Driver No 93 0.111 155 18 0.116 0
TWF2 TWF2 Q6IBS0 Twinfilin-2 chr3 GO:0071363 Not Cancer Driver No 34 0.097 59 8 0.136 0
TWIST1 TWIST1 Q15672 Twist-related protein 1 chr7 GO:0071363 Not Cancer Driver No 23 0.114 132 11 0.083 7
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 GO:0071363 Not Cancer Driver No 141 0.161 136 22 0.162 0
URI1 URI1 O94763 Unconventional prefoldin RPB5 interactor 1 chr19 GO:0071363 Not Cancer Driver No 88 0.164 388 64 0.165 0
USP8 USP8 P40818 Ubiquitin carboxyl-terminal hydrolase 8 chr15 GO:0071363 Census, Compendium Yes 122 0.109 602 69 0.115 0
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 GO:0071363 Not Cancer Driver No 188 0.254 110 28 0.255 0
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0071363 Not Cancer Driver No 27 0.116 41 7 0.171 0
VIL1 VIL1 P09327 Villin-1 chr2 GO:0071363 Not Cancer Driver No 124 0.15 222 38 0.171 0
WASF1_ENST00000392586 WASF1 Q92558 Wiskott-Aldrich syndrome protein family member 1 chr6 GO:0071363 Not Cancer Driver No 63 0.113 445 49 0.11 0
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 GO:0071363 Not Cancer Driver No 65 0.12 62 10 0.161 0
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0071363 Not Cancer Driver No 43 0.132 262 34 0.13 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0071363 Compendium Yes 57 0.169 212 30 0.142 0
ZFP36L2 ZFP36L2 P47974 mRNA decay activator protein ZFP36L2 chr2 GO:0071363 Not Cancer Driver No 73 0.148 324 45 0.139 0
ZPR1 ZPR1 O75312 Zinc finger protein ZPR1 chr11 GO:0071363 Not Cancer Driver No 38 0.083 291 27 0.093 0