Total number of protein in "GO:0070988" GO term: 58
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AICDA | AICDA | Q9GZX7 | Single-stranded DNA cytosine deaminase | chr12 | GO:0070988 | Not Cancer Driver | No | 56 | 0.283 | 0 | 0 | 0.0 | 8 |
ALKBH1 | ALKBH1 | Q13686 | Nucleic acid dioxygenase ALKBH1 | chr14 | GO:0070988 | Not Cancer Driver | No | 55 | 0.141 | 77 | 11 | 0.143 | 0 |
ALKBH2_ENST00000343075 | ALKBH2 | Q6NS38 | DNA oxidative demethylase ALKBH2 | chr12 | GO:0070988 | Not Cancer Driver | No | 34 | 0.13 | 73 | 14 | 0.192 | 0 |
ALKBH3 | ALKBH3 | Q96Q83 | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 | chr11 | GO:0070988 | Not Cancer Driver | No | 42 | 0.147 | 157 | 25 | 0.159 | 0 |
ALKBH4 | ALKBH4 | Q9NXW9 | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 | chr7 | GO:0070988 | Not Cancer Driver | No | 39 | 0.129 | 14 | 2 | 0.143 | 0 |
ALKBH5 | ALKBH5 | Q6P6C2 | RNA demethylase ALKBH5 | chr17 | GO:0070988 | Not Cancer Driver | No | 41 | 0.104 | 200 | 23 | 0.115 | 0 |
APEX1_ENST00000555414 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | GO:0070988 | Not Cancer Driver | No | 34 | 0.107 | 103 | 14 | 0.136 | 0 |
APOBEC1 | APOBEC1 | P41238 | C->U-editing enzyme APOBEC-1 | chr12 | GO:0070988 | Not Cancer Driver | No | 62 | 0.263 | 13 | 1 | 0.077 | 0 |
APOBEC2 | APOBEC2 | Q9Y235 | C->U-editing enzyme APOBEC-2 | chr6 | GO:0070988 | Not Cancer Driver | No | 38 | 0.17 | 36 | 3 | 0.083 | 0 |
APOBEC3A_ENST00000249116 | APOBEC3A | P31941 | DNA dC->dU-editing enzyme APOBEC-3A | chr22 | GO:0070988 | Not Cancer Driver | No | 27 | 0.136 | 8 | 1 | 0.125 | 0 |
APOBEC3B | APOBEC3B | Q9UH17 | DNA dC->dU-editing enzyme APOBEC-3B | chr22 | GO:0070988 | Census | Yes | 61 | 0.16 | 1 | 0 | 0.0 | 0 |
APOBEC3C | APOBEC3C | Q9NRW3 | DNA dC->dU-editing enzyme APOBEC-3C | chr22 | GO:0070988 | Not Cancer Driver | No | 28 | 0.147 | 2 | 0 | 0.0 | 0 |
APOBEC3D | APOBEC3D | Q96AK3 | DNA dC->dU-editing enzyme APOBEC-3D | chr22 | GO:0070988 | Not Cancer Driver | No | 43 | 0.111 | 3 | 0 | 0.0 | 0 |
APOBEC3F | APOBEC3F | Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | chr22 | GO:0070988 | Not Cancer Driver | No | 49 | 0.131 | 0 | 0 | 0.0 | 0 |
APOBEC3G | APOBEC3G | Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | chr22 | GO:0070988 | Not Cancer Driver | No | 61 | 0.159 | 0 | 0 | 0.0 | 0 |
APOBEC3H_ENST00000613677 | APOBEC3H | Q6NTF7 | DNA dC->dU-editing enzyme APOBEC-3H | chr22 | GO:0070988 | Not Cancer Driver | No | 39 | 0.195 | 0 | 0 | 0.0 | 0 |
CYP1A1 | CYP1A1 | P04798 | Cytochrome P450 1A1 | chr15 | GO:0070988 | Not Cancer Driver | No | 81 | 0.158 | 17 | 2 | 0.118 | 0 |
CYP51A1 | CYP51A1 | Q16850 | Lanosterol 14-alpha demethylase | chr7 | GO:0070988 | Not Cancer Driver | No | 49 | 0.096 | 7 | 2 | 0.286 | 0 |
FBXL19 | FBXL19 | Q6PCT2 | F-box/LRR-repeat protein 19 | chr16 | GO:0070988 | Not Cancer Driver | No | 67 | 0.097 | 350 | 38 | 0.109 | 0 |
FTO | FTO | Q9C0B1 | Alpha-ketoglutarate-dependent dioxygenase FTO | chr16 | GO:0070988 | Not Cancer Driver | No | 67 | 0.133 | 53 | 10 | 0.189 | 3 |
HR | HR | O43593 | Lysine-specific demethylase hairless | chr8 | GO:0070988 | Not Cancer Driver | No | 130 | 0.109 | 587 | 74 | 0.126 | 3 |
HSF4 | HSF4 | Q9ULV5 | Heat shock factor protein 4 | chr16 | GO:0070988 | Not Cancer Driver | No | 37 | 0.075 | 327 | 25 | 0.076 | 4 |
JARID2 | JARID2 | Q92833 | Protein Jumonji | chr6 | GO:0070988 | Not Cancer Driver | No | 190 | 0.152 | 724 | 113 | 0.156 | 0 |
JMJD1C | JMJD1C | Q15652 | Probable JmjC domain-containing histone demethylation protein 2C | chr10 | GO:0070988 | Not Cancer Driver | No | 305 | 0.12 | 1640 | 200 | 0.122 | 0 |
JMJD4 | JMJD4 | Q9H9V9 | 2-oxoglutarate and iron-dependent oxygenase JMJD4 | chr1 | GO:0070988 | Not Cancer Driver | No | 67 | 0.145 | 19 | 5 | 0.263 | 0 |
JMJD6_ENST00000397625 | JMJD6 | Q6NYC1 | Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 | chr17 | GO:0070988 | Not Cancer Driver | No | 51 | 0.127 | 133 | 21 | 0.158 | 0 |
KDM1A_ENST00000356634 | KDM1A | O60341 | Lysine-specific histone demethylase 1A | chr1 | GO:0070988 | Not Cancer Driver | No | 67 | 0.079 | 291 | 28 | 0.096 | 3 |
KDM1B_ENST00000449850 | KDM1B | Q8NB78 | Lysine-specific histone demethylase 1B | chr6 | GO:0070988 | Not Cancer Driver | No | 81 | 0.099 | 74 | 11 | 0.149 | 0 |
KDM2A | KDM2A | Q9Y2K7 | Lysine-specific demethylase 2A | chr11 | GO:0070988 | Not Cancer Driver | No | 131 | 0.113 | 387 | 48 | 0.124 | 0 |
KDM2B | KDM2B | Q8NHM5 | Lysine-specific demethylase 2B | chr12 | GO:0070988 | Not Cancer Driver | No | 187 | 0.14 | 617 | 90 | 0.146 | 0 |
KDM3A_ENST00000312912 | KDM3A | Q9Y4C1 | Lysine-specific demethylase 3A | chr2 | GO:0070988 | Not Cancer Driver | No | 136 | 0.103 | 461 | 47 | 0.102 | 0 |
KDM3B | KDM3B | Q7LBC6 | Lysine-specific demethylase 3B | chr5 | GO:0070988 | Compendium | Yes | 221 | 0.125 | 943 | 114 | 0.121 | 7 |
KDM4A | KDM4A | O75164 | Lysine-specific demethylase 4A | chr1 | GO:0070988 | Not Cancer Driver | No | 122 | 0.115 | 337 | 44 | 0.131 | 0 |
KDM4B | KDM4B | O94953 | Lysine-specific demethylase 4B | chr19 | GO:0070988 | Not Cancer Driver | No | 133 | 0.121 | 429 | 49 | 0.114 | 3 |
KDM4C | KDM4C | Q9H3R0 | Lysine-specific demethylase 4C | chr9 | GO:0070988 | Not Cancer Driver | No | 124 | 0.117 | 309 | 40 | 0.129 | 0 |
KDM4D_ENST00000610872 | KDM4D | Q6B0I6 | Lysine-specific demethylase 4D | chr11 | GO:0070988 | Not Cancer Driver | No | 78 | 0.149 | 215 | 33 | 0.153 | 0 |
KDM4E | KDM4E | B2RXH2 | Lysine-specific demethylase 4E | chr11 | GO:0070988 | Not Cancer Driver | No | 43 | 0.085 | 188 | 10 | 0.053 | 0 |
KDM4F | KDM4F | A0A1W2PPD8 | Lysine demethylase 4F | chr11 | GO:0070988 | Not Cancer Driver | No | 1 | 0.002 | 234 | 0 | 0.0 | 0 |
KDM5A | KDM5A | P29375 | Lysine-specific demethylase 5A | chr12 | GO:0070988 | Census, Compendium | Yes | 220 | 0.13 | 503 | 66 | 0.131 | 0 |
KDM5B_ENST00000367265 | KDM5B | Q9UGL1 | Lysine-specific demethylase 5B | chr1 | GO:0070988 | Not Cancer Driver | No | 219 | 0.142 | 388 | 58 | 0.149 | 0 |
KDM5C | KDM5C | P41229 | Lysine-specific demethylase 5C | chrX | GO:0070988 | Census, Compendium | Yes | 167 | 0.107 | 499 | 46 | 0.092 | 10 |
KDM5D | KDM5D | Q9BY66 | Lysine-specific demethylase 5D | chrY | GO:0070988 | Not Cancer Driver | No | 50 | 0.032 | 406 | 11 | 0.027 | 0 |
KDM6A | KDM6A | O15550 | Lysine-specific demethylase 6A | chrX | GO:0070988 | Census, Compendium | Yes | 173 | 0.123 | 648 | 71 | 0.11 | 0 |
KDM6B_ENST00000448097 | KDM6B | O15054 | Lysine-specific demethylase 6B | chr17 | GO:0070988 | Not Cancer Driver | No | 189 | 0.115 | 1278 | 142 | 0.111 | 2 |
KDM7A | KDM7A | Q6ZMT4 | Lysine-specific demethylase 7A | chr7 | GO:0070988 | Not Cancer Driver | No | 112 | 0.119 | 444 | 54 | 0.122 | 0 |
KDM8_ENST00000286096 | KDM8 | Q8N371 | Bifunctional peptidase and arginyl-hydroxylase JMJD5 | chr16 | GO:0070988 | Not Cancer Driver | No | 52 | 0.125 | 29 | 6 | 0.207 | 0 |
MMACHC | MMACHC | Q9Y4U1 | Cyanocobalamin reductase / alkylcobalamin dealkylase | chr1 | GO:0070988 | Not Cancer Driver | No | 29 | 0.103 | 85 | 5 | 0.059 | 14 |
PHF2 | PHF2 | O75151 | Lysine-specific demethylase PHF2 | chr9 | GO:0070988 | Not Cancer Driver | No | 131 | 0.12 | 725 | 80 | 0.11 | 0 |
PHF8 | PHF8 | Q9UPP1 | Histone lysine demethylase PHF8 | chrX | GO:0070988 | Not Cancer Driver | No | 154 | 0.145 | 603 | 93 | 0.154 | 1 |
POR | POR | P16435 | NADPH--cytochrome P450 reductase | chr7 | GO:0070988 | Not Cancer Driver | No | 62 | 0.092 | 93 | 4 | 0.043 | 9 |
RIOX1 | RIOX1 | Q9H6W3 | Ribosomal oxygenase 1 | chr14 | GO:0070988 | Not Cancer Driver | No | 52 | 0.081 | 215 | 15 | 0.07 | 0 |
RIOX2_ENST00000394198 | RIOX2 | Q8IUF8 | Ribosomal oxygenase 2 | chr3 | GO:0070988 | Not Cancer Driver | No | 49 | 0.105 | 74 | 10 | 0.135 | 0 |
TDG | TDG | Q13569 | G/T mismatch-specific thymine DNA glycosylase | chr12 | GO:0070988 | Not Cancer Driver | No | 75 | 0.183 | 185 | 31 | 0.168 | 0 |
TET1 | TET1 | Q8NFU7 | Methylcytosine dioxygenase TET1 | chr10 | GO:0070988 | Census, Compendium | Yes | 316 | 0.148 | 1551 | 234 | 0.151 | 0 |
TET2 | TET2 | Q6N021 | Methylcytosine dioxygenase TET2 | chr4 | GO:0070988 | Census, Compendium | Yes | 191 | 0.095 | 1663 | 176 | 0.106 | 1 |
TET3 | TET3 | O43151 | Methylcytosine dioxygenase TET3 | chr2 | GO:0070988 | Not Cancer Driver | No | 208 | 0.116 | 1272 | 152 | 0.119 | 6 |
UBE2B | UBE2B | P63146 | Ubiquitin-conjugating enzyme E2 B | chr5 | GO:0070988 | Not Cancer Driver | No | 13 | 0.086 | 68 | 6 | 0.088 | 0 |
UTY_ENST00000331397 | UTY | O14607 | Histone demethylase UTY | chrY | GO:0070988 | Not Cancer Driver | No | 38 | 0.028 | 564 | 21 | 0.037 | 0 |