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Total number of protein in "GO:0070647" GO term:  207

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AMFR AMFR Q9UKV5 E3 ubiquitin-protein ligase AMFR chr16 GO:0070647 Not Cancer Driver No 73 0.114 229 30 0.131 0
ANKRD39 ANKRD39 Q53RE8 Ankyrin repeat domain-containing protein 39 chr2 GO:0070647 Not Cancer Driver No 19 0.104 38 2 0.053 0
AREL1 AREL1 O15033 Apoptosis-resistant E3 ubiquitin protein ligase 1 chr14 GO:0070647 Not Cancer Driver No 104 0.126 92 10 0.109 0
ASB4 ASB4 Q9Y574 Ankyrin repeat and SOCS box protein 4 chr7 GO:0070647 Not Cancer Driver No 82 0.192 19 1 0.053 0
ASXL1_ENST00000613218 ASXL1 Q8IXJ9 Polycomb group protein ASXL1 chr20 GO:0070647 Census, Compendium Yes 205 0.133 1300 174 0.134 0
ATXN3 ATXN3 P54252 Ataxin-3 chr14 GO:0070647 Not Cancer Driver No 46 0.127 181 24 0.133 0
ATXN7L3_ENST00000389384 ATXN7L3 Q14CW9 Ataxin-7-like protein 3 chr17 GO:0070647 Not Cancer Driver No 41 0.118 241 27 0.112 0
ATXN7_ENST00000487717 ATXN7 O15265 Ataxin-7 chr3 GO:0070647 Not Cancer Driver No 95 0.107 797 82 0.103 0
BAP1 BAP1 Q92560 Ubiquitin carboxyl-terminal hydrolase BAP1 chr3 GO:0070647 Census, Compendium Yes 141 0.193 418 59 0.141 0
BARD1 BARD1 Q99728 BRCA1-associated RING domain protein 1 chr2 GO:0070647 Census Yes 96 0.124 384 49 0.128 0
BCOR BCOR Q6W2J9 BCL-6 corepressor chrX GO:0070647 Census, Compendium Yes 291 0.166 1285 226 0.176 1
BFAR BFAR Q9NZS9 Bifunctional apoptosis regulator chr16 GO:0070647 Not Cancer Driver No 56 0.124 30 1 0.033 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 GO:0070647 Not Cancer Driver No 50 0.153 150 30 0.2 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 GO:0070647 Census, Compendium Yes 224 0.12 1458 174 0.119 35
BRCC3 BRCC3 P46736 Lys-63-specific deubiquitinase BRCC36 chrX GO:0070647 Not Cancer Driver No 39 0.123 74 7 0.095 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0070647 Census, Compendium Yes 115 0.127 512 56 0.109 4
CDC73 CDC73 Q6P1J9 Parafibromin chr1 GO:0070647 Census, Compendium Yes 110 0.207 210 39 0.186 2
CDK5RAP3_ENST00000338399 CDK5RAP3 Q96JB5 CDK5 regulatory subunit-associated protein 3 chr17 GO:0070647 Not Cancer Driver No 50 0.099 99 20 0.202 0
CNOT4_ENST00000315544 CNOT4 O95628 CCR4-NOT transcription complex subunit 4 chr7 GO:0070647 Not Cancer Driver No 73 0.127 359 35 0.097 0
COPS2_ENST00000388901 COPS2 P61201 COP9 signalosome complex subunit 2 chr15 GO:0070647 Not Cancer Driver No 59 0.133 59 9 0.153 0
COPS3 COPS3 Q9UNS2 COP9 signalosome complex subunit 3 chr17 GO:0070647 Not Cancer Driver No 55 0.13 67 10 0.149 0
COPS4_ENST00000264389 COPS4 Q9BT78 COP9 signalosome complex subunit 4 chr4 GO:0070647 Not Cancer Driver No 50 0.123 13 0 0.0 0
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 GO:0070647 Not Cancer Driver No 36 0.108 32 7 0.219 0
COPS6 COPS6 Q7L5N1 COP9 signalosome complex subunit 6 chr7 GO:0070647 Not Cancer Driver No 38 0.116 30 6 0.2 0
COPS7A_ENST00000534947 COPS7A Q9UBW8 COP9 signalosome complex subunit 7a chr12 GO:0070647 Not Cancer Driver No 32 0.116 74 10 0.135 0
COPS7B_ENST00000410024 COPS7B Q9H9Q2 COP9 signalosome complex subunit 7b chr2 GO:0070647 Not Cancer Driver No 22 0.083 74 6 0.081 0
COPS8 COPS8 Q99627 COP9 signalosome complex subunit 8 chr2 GO:0070647 Not Cancer Driver No 25 0.12 14 2 0.143 0
CTR9 CTR9 Q6PD62 RNA polymerase-associated protein CTR9 homolog chr11 GO:0070647 Not Cancer Driver No 164 0.14 385 48 0.125 0
CTU1 CTU1 Q7Z7A3 Cytoplasmic tRNA 2-thiolation protein 1 chr19 GO:0070647 Not Cancer Driver No 12 0.034 60 1 0.017 0
CTU2_ENST00000453996 CTU2 Q2VPK5 Cytoplasmic tRNA 2-thiolation protein 2 chr16 GO:0070647 Not Cancer Driver No 46 0.089 137 11 0.08 0
CUL3 CUL3 Q13618 Cullin-3 chr2 GO:0070647 Census, Compendium Yes 123 0.16 167 23 0.138 3
CUL4B CUL4B Q13620 Cullin-4B chrX GO:0070647 Not Cancer Driver No 138 0.151 207 38 0.184 2
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 GO:0070647 Census, Compendium Yes 116 0.121 213 31 0.146 3
DCUN1D1 DCUN1D1 Q96GG9 DCN1-like protein 1 chr3 GO:0070647 Not Cancer Driver No 34 0.131 13 0 0.0 0
DCUN1D2 DCUN1D2 Q6PH85 DCN1-like protein 2 chr13 GO:0070647 Not Cancer Driver No 36 0.139 29 7 0.241 0
DCUN1D3 DCUN1D3 Q8IWE4 DCN1-like protein 3 chr16 GO:0070647 Not Cancer Driver No 36 0.118 118 9 0.076 0
DCUN1D4_ENST00000334635 DCUN1D4 Q92564 DCN1-like protein 4 chr4 GO:0070647 Not Cancer Driver No 51 0.175 57 12 0.211 0
DCUN1D5 DCUN1D5 Q9BTE7 DCN1-like protein 5 chr11 GO:0070647 Not Cancer Driver No 18 0.076 7 0 0.0 0
DDB1 DDB1 Q16531 DNA damage-binding protein 1 chr11 GO:0070647 Not Cancer Driver No 126 0.111 50 8 0.16 4
DDB2 DDB2 Q92466 DNA damage-binding protein 2 chr11 GO:0070647 Census, Compendium Yes 45 0.105 70 5 0.071 2
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 GO:0070647 Not Cancer Driver No 34 0.108 181 23 0.127 0
DESI1 DESI1 Q6ICB0 Desumoylating isopeptidase 1 chr22 GO:0070647 Not Cancer Driver No 23 0.137 34 6 0.176 0
DTX3L DTX3L Q8TDB6 E3 ubiquitin-protein ligase DTX3L chr3 GO:0070647 Not Cancer Driver No 86 0.116 260 24 0.092 0
ENY2 ENY2 Q9NPA8 Transcription and mRNA export factor ENY2 chr8 GO:0070647 Not Cancer Driver No 17 0.168 11 4 0.364 0
ERCC8 ERCC8 Q13216 DNA excision repair protein ERCC-8 chr5 GO:0070647 Not Cancer Driver No 25 0.063 53 8 0.151 7
GPS1_ENST00000306823 GPS1 Q13098 COP9 signalosome complex subunit 1 chr17 GO:0070647 Not Cancer Driver No 62 0.126 106 14 0.132 0
HECTD1 HECTD1 Q9ULT8 E3 ubiquitin-protein ligase HECTD1 chr14 GO:0070647 Not Cancer Driver No 274 0.105 991 108 0.109 0
HERC5 HERC5 Q9UII4 E3 ISG15--protein ligase HERC5 chr4 GO:0070647 Not Cancer Driver No 124 0.121 118 12 0.102 0
HINT1 HINT1 P49773 Adenosine 5'-monophosphoramidase HINT1 chr5 GO:0070647 Not Cancer Driver No 11 0.087 6 0 0.0 6
ISG15 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 GO:0070647 Not Cancer Driver No 12 0.073 24 2 0.083 0
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 GO:0070647 Not Cancer Driver No 95 0.105 335 42 0.125 0
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 GO:0070647 Not Cancer Driver No 88 0.105 251 17 0.068 0
KDM2B KDM2B Q8NHM5 Lysine-specific demethylase 2B chr12 GO:0070647 Not Cancer Driver No 187 0.14 617 90 0.146 0
KLHL20 KLHL20 Q9Y2M5 Kelch-like protein 20 chr1 GO:0070647 Not Cancer Driver No 83 0.136 143 17 0.119 0
KLHL24_ENST00000242810 KLHL24 Q6TFL4 Kelch-like protein 24 chr3 GO:0070647 Not Cancer Driver No 102 0.17 17 6 0.353 0
LEO1 LEO1 Q8WVC0 RNA polymerase-associated protein LEO1 chr15 GO:0070647 Not Cancer Driver No 74 0.111 611 69 0.113 0
LRSAM1_ENST00000373322 LRSAM1 Q6UWE0 E3 ubiquitin-protein ligase LRSAM1 chr9 GO:0070647 Not Cancer Driver No 86 0.119 240 30 0.125 1
LTN1_ENST00000361371 LTN1 O94822 E3 ubiquitin-protein ligase listerin chr21 GO:0070647 Not Cancer Driver No 192 0.109 124 23 0.185 0
MARCH5 MARCHF5 Q9NX47 E3 ubiquitin-protein ligase MARCHF5 chr10 GO:0070647 Not Cancer Driver No 27 0.097 0 0 0.0 0
MARCH7 MARCHF7 Q9H992 E3 ubiquitin-protein ligase MARCHF7 chr2 GO:0070647 Not Cancer Driver No 85 0.121 550 68 0.124 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 GO:0070647 Census, Compendium Yes 56 0.114 297 37 0.125 0
MOCS3 MOCS3 O95396 Adenylyltransferase and sulfurtransferase MOCS3 chr20 GO:0070647 Not Cancer Driver No 61 0.133 15 5 0.333 0
MYSM1 MYSM1 Q5VVJ2 Deubiquitinase MYSM1 chr1 GO:0070647 Not Cancer Driver No 78 0.094 345 26 0.075 1
NAE1_ENST00000290810 NAE1 Q13564 NEDD8-activating enzyme E1 regulatory subunit chr16 GO:0070647 Not Cancer Driver No 39 0.073 69 3 0.043 0
NEDD8 NEDD8 Q15843 NEDD8 chr14 GO:0070647 Not Cancer Driver No 10 0.123 36 5 0.139 0
NFX1 NFX1 Q12986 Transcriptional repressor NF-X1 chr9 GO:0070647 Not Cancer Driver No 121 0.108 491 46 0.094 0
OTUB2 OTUB2 Q96DC9 Ubiquitin thioesterase OTUB2 chr14 GO:0070647 Not Cancer Driver No 30 0.128 0 0 0.0 0
OTUD3 OTUD3 Q5T2D3 OTU domain-containing protein 3 chr1 GO:0070647 Not Cancer Driver No 43 0.108 280 25 0.089 0
OTUD6A OTUD6A Q7L8S5 OTU domain-containing protein 6A chrX GO:0070647 Not Cancer Driver No 71 0.247 126 25 0.198 0
OTUD7A OTUD7A Q8TE49 OTU domain-containing protein 7A chr15 GO:0070647 Not Cancer Driver No 121 0.131 591 65 0.11 0
OTUD7B OTUD7B Q6GQQ9 OTU domain-containing protein 7B chr1 GO:0070647 Not Cancer Driver No 124 0.147 537 87 0.162 0
OTULIN OTULIN Q96BN8 Ubiquitin thioesterase otulin chr5 GO:0070647 Not Cancer Driver No 47 0.134 97 5 0.052 2
PAF1 PAF1 Q8N7H5 RNA polymerase II-associated factor 1 homolog chr19 GO:0070647 Not Cancer Driver No 77 0.145 378 56 0.148 0
PCGF1 PCGF1 Q9BSM1 Polycomb group RING finger protein 1 chr2 GO:0070647 Not Cancer Driver No 28 0.108 8 0 0.0 0
PCGF3 PCGF3 Q3KNV8 Polycomb group RING finger protein 3 chr4 GO:0070647 Not Cancer Driver No 38 0.157 47 11 0.234 0
PCGF5 PCGF5 Q86SE9 Polycomb group RING finger protein 5 chr10 GO:0070647 Not Cancer Driver No 31 0.121 52 5 0.096 0
PCGF6 PCGF6 Q9BYE7 Polycomb group RING finger protein 6 chr10 GO:0070647 Not Cancer Driver No 29 0.083 142 11 0.077 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0070647 Not Cancer Driver No 110 0.237 78 15 0.192 31
RAD18 RAD18 Q9NS91 E3 ubiquitin-protein ligase RAD18 chr3 GO:0070647 Not Cancer Driver No 59 0.119 328 43 0.131 0
RAG1 RAG1 P15918 V(D)J recombination-activating protein 1 chr11 GO:0070647 Not Cancer Driver No 204 0.196 208 43 0.207 36
RBCK1 RBCK1 Q9BYM8 RanBP-type and C3HC4-type zinc finger-containing protein 1 chr20 GO:0070647 Not Cancer Driver No 52 0.102 140 14 0.1 2
RBX1 RBX1 P62877 E3 ubiquitin-protein ligase RBX1 chr22 GO:0070647 Not Cancer Driver No 10 0.093 18 1 0.056 0
RING1 RING1 Q06587 E3 ubiquitin-protein ligase RING1 chr6 GO:0070647 Not Cancer Driver No 60 0.148 302 44 0.146 0
RNF10_ENST00000325954 RNF10 Q8N5U6 RING finger protein 10 chr12 GO:0070647 Not Cancer Driver No 108 0.133 455 63 0.138 0
RNF11 RNF11 Q9Y3C5 RING finger protein 11 chr1 GO:0070647 Not Cancer Driver No 17 0.11 76 7 0.092 0
RNF112 RNF112 Q9ULX5 RING finger protein 112 chr17 GO:0070647 Not Cancer Driver No 86 0.136 168 26 0.155 0
RNF115 RNF115 Q9Y4L5 E3 ubiquitin-protein ligase RNF115 chr1 GO:0070647 Not Cancer Driver No 30 0.099 136 14 0.103 0
RNF122 RNF122 Q9H9V4 RING finger protein 122 chr8 GO:0070647 Not Cancer Driver No 24 0.155 0 0 0.0 0
RNF133 RNF133 Q8WVZ7 E3 ubiquitin-protein ligase RNF133 chr7 GO:0070647 Not Cancer Driver No 76 0.202 60 5 0.083 0
RNF13_ENST00000392894 RNF13 O43567 E3 ubiquitin-protein ligase RNF13 chr3 GO:0070647 Not Cancer Driver No 45 0.118 107 17 0.159 2
RNF141 RNF141 Q8WVD5 RING finger protein 141 chr11 GO:0070647 Not Cancer Driver No 28 0.122 48 4 0.083 0
RNF146 RNF146 Q9NTX7 E3 ubiquitin-protein ligase RNF146 chr6 GO:0070647 Not Cancer Driver No 37 0.103 206 24 0.117 0
RNF157 RNF157 Q96PX1 E3 ubiquitin ligase RNF157 chr17 GO:0070647 Not Cancer Driver No 76 0.112 375 39 0.104 0
RNF168 RNF168 Q8IYW5 E3 ubiquitin-protein ligase RNF168 chr3 GO:0070647 Not Cancer Driver No 77 0.135 471 66 0.14 0
RNF181 RNF181 Q9P0P0 E3 ubiquitin-protein ligase RNF181 chr2 GO:0070647 Not Cancer Driver No 15 0.098 63 8 0.127 0
RNF183_ENST00000297894 RNF183 Q96D59 E3 ubiquitin-protein ligase RNF183 chr9 GO:0070647 Not Cancer Driver No 22 0.115 29 1 0.034 0
RNF185 RNF185 Q96GF1 E3 ubiquitin-protein ligase RNF185 chr22 GO:0070647 Not Cancer Driver No 25 0.13 82 15 0.183 0
RNF186 RNF186 Q9NXI6 E3 ubiquitin-protein ligase RNF186 chr1 GO:0070647 Not Cancer Driver No 27 0.119 11 3 0.273 0
RNF187_ENST00000639044 RNF187 Q5TA31 E3 ubiquitin-protein ligase RNF187 chr1 GO:0070647 Not Cancer Driver No 2 0.009 104 1 0.01 0
RNF19B RNF19B Q6ZMZ0 E3 ubiquitin-protein ligase RNF19B chr1 GO:0070647 Not Cancer Driver No 58 0.079 344 24 0.07 0
RNF2 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 GO:0070647 Not Cancer Driver No 40 0.119 203 22 0.108 0
RNF20 RNF20 Q5VTR2 E3 ubiquitin-protein ligase BRE1A chr9 GO:0070647 Not Cancer Driver No 126 0.129 561 64 0.114 0
RNF208 RNF208 Q9H0X6 RING finger protein 208 chr9 GO:0070647 Not Cancer Driver No 20 0.077 113 9 0.08 0
RNF213 RNF213 Q63HN8 E3 ubiquitin-protein ligase RNF213 chr17 GO:0070647 Census, Compendium Yes 560 0.108 623 75 0.12 3
RNF219 OBI1 Q5W0B1 ORC ubiquitin ligase 1 chr13 GO:0070647 Not Cancer Driver No 96 0.132 486 67 0.138 0
RNF220_ENST00000361799 RNF220 Q5VTB9 E3 ubiquitin-protein ligase RNF220 chr1 GO:0070647 Not Cancer Driver No 104 0.184 401 75 0.187 0
RNF31 RNF31 Q96EP0 E3 ubiquitin-protein ligase RNF31 chr14 GO:0070647 Not Cancer Driver No 142 0.132 319 45 0.141 0
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 GO:0070647 Not Cancer Driver No 14 0.074 117 7 0.06 0
RNF40 RNF40 O75150 E3 ubiquitin-protein ligase BRE1B chr16 GO:0070647 Not Cancer Driver No 132 0.132 645 80 0.124 0
RNF41_ENST00000615206 RNF41 Q9H4P4 E3 ubiquitin-protein ligase NRDP1 chr12 GO:0070647 Not Cancer Driver No 44 0.139 33 2 0.061 0
RNF6 RNF6 Q9Y252 E3 ubiquitin-protein ligase RNF6 chr13 GO:0070647 Compendium Yes 91 0.133 601 87 0.145 0
RNF7 RNF7 Q9UBF6 RING-box protein 2 chr3 GO:0070647 Not Cancer Driver No 17 0.15 0 0 0.0 0
RNF8 RNF8 O76064 E3 ubiquitin-protein ligase RNF8 chr6 GO:0070647 Not Cancer Driver No 56 0.115 226 29 0.128 0
RNFT1 RNFT1 Q5M7Z0 E3 ubiquitin-protein ligase RNFT1 chr17 GO:0070647 Not Cancer Driver No 37 0.085 117 18 0.154 0
RYBP RYBP Q8N488 RING1 and YY1-binding protein chr3 GO:0070647 Not Cancer Driver No 37 0.162 214 37 0.173 0
SENP1 SENP1 Q9P0U3 Sentrin-specific protease 1 chr12 GO:0070647 Not Cancer Driver No 64 0.099 355 44 0.124 0
SENP2 SENP2 Q9HC62 Sentrin-specific protease 2 chr3 GO:0070647 Not Cancer Driver No 73 0.124 285 38 0.133 0
SENP3_ENST00000429205 SENP3 Q9H4L4 Sentrin-specific protease 3 chr17 GO:0070647 Not Cancer Driver No 53 0.092 288 30 0.104 0
SENP5 SENP5 Q96HI0 Sentrin-specific protease 5 chr3 GO:0070647 Not Cancer Driver No 85 0.113 293 34 0.116 0
SENP6 SENP6 Q9GZR1 Sentrin-specific protease 6 chr6 GO:0070647 Not Cancer Driver No 120 0.108 612 59 0.096 0
SENP7 SENP7 Q9BQF6 Sentrin-specific protease 7 chr3 GO:0070647 Not Cancer Driver No 149 0.142 523 73 0.14 0
SF3B3 SF3B3 Q15393 Splicing factor 3B subunit 3 chr16 GO:0070647 Not Cancer Driver No 154 0.127 145 19 0.131 0
SF3B5 SF3B5 Q9BWJ5 Splicing factor 3B subunit 5 chr6 GO:0070647 Not Cancer Driver No 8 0.093 16 2 0.125 0
SGF29 SGF29 Q96ES7 SAGA-associated factor 29 chr16 GO:0070647 Not Cancer Driver No 31 0.106 131 17 0.13 0
SH3RF1 SH3RF1 Q7Z6J0 E3 ubiquitin-protein ligase SH3RF1 chr4 GO:0070647 Not Cancer Driver No 109 0.123 586 72 0.123 0
SH3RF2 SH3RF2 Q8TEC5 E3 ubiquitin-protein ligase SH3RF2 chr5 GO:0070647 Not Cancer Driver No 151 0.207 455 101 0.222 0
SH3RF3 SH3RF3 Q8TEJ3 E3 ubiquitin-protein ligase SH3RF3 chr2 GO:0070647 Not Cancer Driver No 98 0.111 564 53 0.094 0
SHARPIN SHARPIN Q9H0F6 Sharpin chr8 GO:0070647 Not Cancer Driver No 34 0.088 237 16 0.068 0
SKP1_ENST00000517625 SKP1 P63208 S-phase kinase-associated protein 1 chr5 GO:0070647 Not Cancer Driver No 19 0.117 95 17 0.179 0
SPATA2_ENST00000289431 SPATA2 Q9UM82 Spermatogenesis-associated protein 2 chr20 GO:0070647 Not Cancer Driver No 70 0.135 235 39 0.166 0
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 GO:0070647 Not Cancer Driver No 35 0.116 112 14 0.125 12
SUPT20H_ENST00000350612 SUPT20H Q8NEM7 Transcription factor SPT20 homolog chr13 GO:0070647 Not Cancer Driver No 93 0.119 426 56 0.131 0
SUPT3H_ENST00000371459 SUPT3H O75486 Transcription initiation protein SPT3 homolog chr6 GO:0070647 Not Cancer Driver No 49 0.155 49 4 0.082 0
SUPT7L SUPT7L O94864 STAGA complex 65 subunit gamma chr2 GO:0070647 Not Cancer Driver No 41 0.099 281 30 0.107 0
TADA1 TADA1 Q96BN2 Transcriptional adapter 1 chr1 GO:0070647 Not Cancer Driver No 38 0.113 116 12 0.103 0
TADA2B TADA2B Q86TJ2 Transcriptional adapter 2-beta chr4 GO:0070647 Not Cancer Driver No 55 0.131 128 19 0.148 0
TADA3 TADA3 O75528 Transcriptional adapter 3 chr3 GO:0070647 Not Cancer Driver No 54 0.125 353 43 0.122 0
TAF10 TAF10 Q12962 Transcription initiation factor TFIID subunit 10 chr11 GO:0070647 Not Cancer Driver No 17 0.078 131 4 0.031 0
TAF12_ENST00000373824 TAF12 Q16514 Transcription initiation factor TFIID subunit 12 chr1 GO:0070647 Not Cancer Driver No 11 0.068 107 7 0.065 0
TAF2 TAF2 Q6P1X5 Transcription initiation factor TFIID subunit 2 chr8 GO:0070647 Not Cancer Driver No 129 0.108 241 34 0.141 1
TAF4 TAF4 O00268 Transcription initiation factor TFIID subunit 4 chr20 GO:0070647 Not Cancer Driver No 112 0.103 975 96 0.098 0
TAF5 TAF5 Q15542 Transcription initiation factor TFIID subunit 5 chr10 GO:0070647 Not Cancer Driver No 61 0.076 294 12 0.041 0
TAF5L TAF5L O75529 TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L chr1 GO:0070647 Not Cancer Driver No 87 0.148 69 11 0.159 0
TAF6L TAF6L Q9Y6J9 TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L chr11 GO:0070647 Not Cancer Driver No 64 0.103 246 20 0.081 0
TAF6_ENST00000344095 TAF6 P49848 Transcription initiation factor TFIID subunit 6 chr7 GO:0070647 Not Cancer Driver No 79 0.117 288 32 0.111 2
TAF7 TAF7 Q15545 Transcription initiation factor TFIID subunit 7 chr5 GO:0070647 Not Cancer Driver No 40 0.115 258 31 0.12 0
TAF9 TAF9 Q16594 Transcription initiation factor TFIID subunit 9 chr5 GO:0070647 Not Cancer Driver No 25 0.095 203 19 0.094 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:0070647 Census, Compendium Yes 98 0.124 231 33 0.143 1
TOR1A TOR1A O14656 Torsin-1A chr9 GO:0070647 Not Cancer Driver No 33 0.099 0 0 0.0 3
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0070647 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0070647 Not Cancer Driver No 67 0.128 62 7 0.113 0
TRIM13_ENST00000378182 TRIM13 O60858 E3 ubiquitin-protein ligase TRIM13 chr13 GO:0070647 Not Cancer Driver No 53 0.13 1 0 0.0 0
TRIM17_ENST00000366698 TRIM17 Q9Y577 E3 ubiquitin-protein ligase TRIM17 chr1 GO:0070647 Not Cancer Driver No 64 0.134 127 19 0.15 0
TRIM21 TRIM21 P19474 E3 ubiquitin-protein ligase TRIM21 chr11 GO:0070647 Not Cancer Driver No 85 0.179 49 7 0.143 0
TRIM32 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 GO:0070647 Not Cancer Driver No 82 0.126 87 10 0.115 3
TRIM37 TRIM37 O94972 E3 ubiquitin-protein ligase TRIM37 chr17 GO:0070647 Not Cancer Driver No 119 0.123 492 60 0.122 3
TRIM40_ENST00000376724 TRIM40 Q6P9F5 E3 ubiquitin ligase TRIM40 chr6 GO:0070647 Not Cancer Driver No 44 0.171 84 12 0.143 0
TRIM52 TRIM52 Q96A61 E3 ubiquitin-protein ligase TRIM52 chr5 GO:0070647 Not Cancer Driver No 23 0.077 147 13 0.088 0
TRIM58 TRIM58 Q8NG06 E3 ubiquitin-protein ligase TRIM58 chr1 GO:0070647 Not Cancer Driver No 194 0.399 84 41 0.488 0
TRIM62 TRIM62 Q9BVG3 E3 ubiquitin-protein ligase TRIM62 chr1 GO:0070647 Not Cancer Driver No 58 0.122 80 14 0.175 0
TRIM68 TRIM68 Q6AZZ1 E3 ubiquitin-protein ligase TRIM68 chr11 GO:0070647 Not Cancer Driver No 74 0.153 37 7 0.189 0
TRIM71 TRIM71 Q2Q1W2 E3 ubiquitin-protein ligase TRIM71 chr3 GO:0070647 Not Cancer Driver No 124 0.143 163 21 0.129 2
TRRAP TRRAP Q9Y4A5 Transformation/transcription domain-associated protein chr7 GO:0070647 Census, Compendium Yes 554 0.144 402 59 0.147 8
UBA3 UBA3 Q8TBC4 NEDD8-activating enzyme E1 catalytic subunit chr3 GO:0070647 Not Cancer Driver No 48 0.104 44 4 0.091 0
UBA5 UBA5 Q9GZZ9 Ubiquitin-like modifier-activating enzyme 5 chr3 GO:0070647 Not Cancer Driver No 41 0.101 126 8 0.063 7
UBA7 UBA7 P41226 Ubiquitin-like modifier-activating enzyme 7 chr3 GO:0070647 Not Cancer Driver No 92 0.091 166 15 0.09 0
UBE2A UBE2A P49459 Ubiquitin-conjugating enzyme E2 A chrX GO:0070647 Compendium Yes 35 0.23 67 13 0.194 2
UBE2B UBE2B P63146 Ubiquitin-conjugating enzyme E2 B chr5 GO:0070647 Not Cancer Driver No 13 0.086 68 6 0.088 0
UBE2D2 UBE2D2 P62837 Ubiquitin-conjugating enzyme E2 D2 chr5 GO:0070647 Compendium Yes 19 0.129 13 1 0.077 0
UBE2D3_ENST00000394801 UBE2D3 P61077 Ubiquitin-conjugating enzyme E2 D3 chr4 GO:0070647 Not Cancer Driver No 21 0.143 13 4 0.308 0
UBE2D4 UBE2D4 Q9Y2X8 Ubiquitin-conjugating enzyme E2 D4 chr7 GO:0070647 Not Cancer Driver No 13 0.088 21 1 0.048 0
UBE2E1 UBE2E1 P51965 Ubiquitin-conjugating enzyme E2 E1 chr3 GO:0070647 Not Cancer Driver No 21 0.109 78 10 0.128 0
UBE2E2_ENST00000425792 UBE2E2 Q96LR5 Ubiquitin-conjugating enzyme E2 E2 chr3 GO:0070647 Not Cancer Driver No 28 0.139 90 15 0.167 0
UBE2F_ENST00000272930 UBE2F Q969M7 NEDD8-conjugating enzyme UBE2F chr2 GO:0070647 Not Cancer Driver No 21 0.114 19 5 0.263 0
UBE2L6 UBE2L6 O14933 Ubiquitin/ISG15-conjugating enzyme E2 L6 chr11 GO:0070647 Not Cancer Driver No 19 0.124 7 1 0.143 0
UBE2M UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 GO:0070647 Not Cancer Driver No 30 0.164 32 6 0.188 0
UBE2S UBE2S Q16763 Ubiquitin-conjugating enzyme E2 S chr19 GO:0070647 Not Cancer Driver No 25 0.113 102 12 0.118 0
UBE2T UBE2T Q9NPD8 Ubiquitin-conjugating enzyme E2 T chr1 GO:0070647 Not Cancer Driver No 12 0.061 97 9 0.093 1
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 GO:0070647 Not Cancer Driver No 141 0.161 136 22 0.162 0
UBE3C UBE3C Q15386 Ubiquitin-protein ligase E3C chr7 GO:0070647 Not Cancer Driver No 143 0.132 65 12 0.185 0
UBE3D UBE3D Q7Z6J8 E3 ubiquitin-protein ligase E3D chr6 GO:0070647 Not Cancer Driver No 51 0.131 9 3 0.333 0
UFC1 UFC1 Q9Y3C8 Ubiquitin-fold modifier-conjugating enzyme 1 chr1 GO:0070647 Not Cancer Driver No 24 0.144 10 0 0.0 2
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 GO:0070647 Not Cancer Driver No 109 0.137 141 24 0.17 0
UFM1_ENST00000239878 UFM1 P61960 Ubiquitin-fold modifier 1 chr13 GO:0070647 Not Cancer Driver No 10 0.118 0 0 0.0 1
UHRF1_ENST00000616255 UHRF1 Q96T88 E3 ubiquitin-protein ligase UHRF1 chr19 GO:0070647 Not Cancer Driver No 97 0.122 353 49 0.139 0
UHRF2 UHRF2 Q96PU4 E3 ubiquitin-protein ligase UHRF2 chr9 GO:0070647 Not Cancer Driver No 88 0.11 253 22 0.087 0
UIMC1_ENST00000511320 UIMC1 Q96RL1 BRCA1-A complex subunit RAP80 chr5 GO:0070647 Not Cancer Driver No 64 0.089 609 51 0.084 0
URM1_ENST00000372853 URM1 Q9BTM9 Ubiquitin-related modifier 1 chr9 GO:0070647 Not Cancer Driver No 7 0.069 0 0 0.0 0
USP13 USP13 Q92995 Ubiquitin carboxyl-terminal hydrolase 13 chr3 GO:0070647 Not Cancer Driver No 121 0.14 224 42 0.188 0
USP15 USP15 Q9Y4E8 Ubiquitin carboxyl-terminal hydrolase 15 chr12 GO:0070647 Not Cancer Driver No 136 0.139 259 39 0.151 0
USP16 USP16 Q9Y5T5 Ubiquitin carboxyl-terminal hydrolase 16 chr21 GO:0070647 Not Cancer Driver No 98 0.119 394 42 0.107 0
USP1_ENST00000371146 USP1 O94782 Ubiquitin carboxyl-terminal hydrolase 1 chr1 GO:0070647 Not Cancer Driver No 63 0.08 403 30 0.074 0
USP22 USP22 Q9UPT9 Ubiquitin carboxyl-terminal hydrolase 22 chr17 GO:0070647 Not Cancer Driver No 64 0.122 50 1 0.02 0
USP30 USP30 Q70CQ3 Ubiquitin carboxyl-terminal hydrolase 30 chr12 GO:0070647 Not Cancer Driver No 76 0.147 136 26 0.191 0
USP37_ENST00000454775 USP37 Q86T82 Ubiquitin carboxyl-terminal hydrolase 37 chr2 GO:0070647 Not Cancer Driver No 112 0.114 530 62 0.117 0
USP47 USP47 Q96K76 Ubiquitin carboxyl-terminal hydrolase 47 chr11 GO:0070647 Not Cancer Driver No 137 0.1 425 39 0.092 0
USP49 USP49 Q70CQ1 Ubiquitin carboxyl-terminal hydrolase 49 chr6 GO:0070647 Not Cancer Driver No 81 0.118 190 19 0.1 0
USP7 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 GO:0070647 Not Cancer Driver No 170 0.154 215 45 0.209 0
USP9X_ENST00000378308 USP9X Q93008 Probable ubiquitin carboxyl-terminal hydrolase FAF-X chrX GO:0070647 Census, Compendium Yes 339 0.133 405 51 0.126 1
USPL1 USPL1 Q5W0Q7 SUMO-specific isopeptidase USPL1 chr13 GO:0070647 Not Cancer Driver No 107 0.098 578 55 0.095 0
VCPIP1 VCPIP1 Q96JH7 Deubiquitinating protein VCPIP1 chr8 GO:0070647 Not Cancer Driver No 133 0.109 543 61 0.112 0
WAC WAC Q9BTA9 WW domain-containing adapter protein with coiled-coil chr10 GO:0070647 Not Cancer Driver No 106 0.164 571 95 0.166 0
WSB1 WSB1 Q9Y6I7 WD repeat and SOCS box-containing protein 1 chr17 GO:0070647 Not Cancer Driver No 48 0.114 25 3 0.12 0
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 GO:0070647 Not Cancer Driver No 112 0.129 422 57 0.135 0
YOD1 YOD1 Q5VVQ6 Ubiquitin thioesterase OTU1 chr1 GO:0070647 Not Cancer Driver No 30 0.086 120 6 0.05 0
ZBED1 ZBED1 O96006 E3 SUMO-protein ligase ZBED1 chrX GO:0070647 Not Cancer Driver No 137 0.197 97 12 0.124 0
ZRANB1 ZRANB1 Q9UGI0 Ubiquitin thioesterase ZRANB1 chr10 GO:0070647 Not Cancer Driver No 87 0.123 158 25 0.158 0