Total number of protein in "GO:0070555" GO term: 104
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACOD1 | ACOD1 | A6NK06 | Cis-aconitate decarboxylase | chr13 | GO:0070555 | Not Cancer Driver | No | 5 | 0.01 | 36 | 0 | 0.0 | 0 |
| ADAMTS12 | ADAMTS12 | P58397 | A disintegrin and metalloproteinase with thrombospondin motifs 12 | chr5 | GO:0070555 | Not Cancer Driver | No | 504 | 0.316 | 374 | 128 | 0.342 | 0 |
| ADAMTS7 | ADAMTS7 | Q9UKP4 | A disintegrin and metalloproteinase with thrombospondin motifs 7 | chr15 | GO:0070555 | Not Cancer Driver | No | 244 | 0.145 | 640 | 100 | 0.156 | 0 |
| AES_ENST00000327141 | TLE5 | Q08117 | TLE family member 5 | chr19 | GO:0070555 | Not Cancer Driver | No | 16 | 0.081 | 77 | 7 | 0.091 | 0 |
| AKAP12 | AKAP12 | Q02952 | A-kinase anchor protein 12 | chr6 | GO:0070555 | Not Cancer Driver | No | 215 | 0.121 | 1770 | 214 | 0.121 | 0 |
| ANKRD1 | ANKRD1 | Q15327 | Ankyrin repeat domain-containing protein 1 | chr10 | GO:0070555 | Not Cancer Driver | No | 52 | 0.163 | 83 | 13 | 0.157 | 0 |
| ANXA1_ENST00000257497 | ANXA1 | P04083 | Annexin A1 | chr9 | GO:0070555 | Not Cancer Driver | No | 59 | 0.171 | 61 | 12 | 0.197 | 0 |
| APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | GO:0070555 | Not Cancer Driver | No | 128 | 0.166 | 418 | 71 | 0.17 | 17 |
| AQP4 | AQP4 | P55087 | Aquaporin-4 | chr18 | GO:0070555 | Not Cancer Driver | No | 50 | 0.155 | 30 | 9 | 0.3 | 0 |
| CACTIN | CACTIN | Q8WUQ7 | Cactin | chr19 | GO:0070555 | Not Cancer Driver | No | 94 | 0.124 | 503 | 54 | 0.107 | 0 |
| CAMP | CAMP | P49913 | Cathelicidin antimicrobial peptide | chr3 | GO:0070555 | Not Cancer Driver | No | 25 | 0.147 | 48 | 4 | 0.083 | 0 |
| CCL1 | CCL1 | P22362 | C-C motif chemokine 1 | chr17 | GO:0070555 | Not Cancer Driver | No | 27 | 0.281 | 0 | 0 | 0.0 | 0 |
| CCL11 | CCL11 | P51671 | Eotaxin | chr17 | GO:0070555 | Not Cancer Driver | No | 18 | 0.186 | 14 | 3 | 0.214 | 0 |
| CCL13 | CCL13 | Q99616 | C-C motif chemokine 13 | chr17 | GO:0070555 | Not Cancer Driver | No | 15 | 0.153 | 1 | 0 | 0.0 | 0 |
| CCL17_ENST00000616880 | CCL17 | Q92583 | C-C motif chemokine 17 | chr16 | GO:0070555 | Not Cancer Driver | No | 10 | 0.106 | 0 | 0 | 0.0 | 0 |
| CCL19 | CCL19 | Q99731 | C-C motif chemokine 19 | chr9 | GO:0070555 | Not Cancer Driver | No | 10 | 0.102 | 7 | 0 | 0.0 | 0 |
| CCL2 | CCL2 | P13500 | C-C motif chemokine 2 | chr17 | GO:0070555 | Not Cancer Driver | No | 20 | 0.202 | 15 | 5 | 0.333 | 0 |
| CCL20 | CCL20 | P78556 | C-C motif chemokine 20 | chr2 | GO:0070555 | Not Cancer Driver | No | 16 | 0.167 | 0 | 0 | 0.0 | 0 |
| CCL21 | CCL21 | O00585 | C-C motif chemokine 21 | chr9 | GO:0070555 | Not Cancer Driver | No | 14 | 0.104 | 59 | 6 | 0.102 | 0 |
| CCL22 | CCL22 | O00626 | C-C motif chemokine 22 | chr16 | GO:0070555 | Not Cancer Driver | No | 19 | 0.204 | 0 | 0 | 0.0 | 0 |
| CCL24_ENST00000222902 | CCL24 | O00175 | C-C motif chemokine 24 | chr7 | GO:0070555 | Not Cancer Driver | No | 25 | 0.21 | 23 | 3 | 0.13 | 0 |
| CCL25 | CCL25 | O15444 | C-C motif chemokine 25 | chr19 | GO:0070555 | Not Cancer Driver | No | 20 | 0.133 | 26 | 6 | 0.231 | 0 |
| CCL26_ENST00000005180 | CCL26 | Q9Y258 | C-C motif chemokine 26 | chr7 | GO:0070555 | Not Cancer Driver | No | 9 | 0.096 | 0 | 0 | 0.0 | 0 |
| CCL7 | CCL7 | P80098 | C-C motif chemokine 7 | chr17 | GO:0070555 | Not Cancer Driver | No | 30 | 0.303 | 13 | 3 | 0.231 | 0 |
| CCL8 | CCL8 | P80075 | C-C motif chemokine 8 | chr17 | GO:0070555 | Not Cancer Driver | No | 17 | 0.172 | 0 | 0 | 0.0 | 0 |
| CD38 | CD38 | P28907 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | chr4 | GO:0070555 | Not Cancer Driver | No | 54 | 0.18 | 3 | 1 | 0.333 | 0 |
| CD40 | CD40 | P25942 | Tumor necrosis factor receptor superfamily member 5 | chr20 | GO:0070555 | Not Cancer Driver | No | 39 | 0.141 | 56 | 6 | 0.107 | 2 |
| CD47 | CD47 | Q08722 | Leukocyte surface antigen CD47 | chr3 | GO:0070555 | Not Cancer Driver | No | 37 | 0.115 | 0 | 0 | 0.0 | 0 |
| CEBPB | CEBPB | P17676 | CCAAT/enhancer-binding protein beta | chr20 | GO:0070555 | Not Cancer Driver | No | 3 | 0.009 | 276 | 2 | 0.007 | 0 |
| CHI3L1 | CHI3L1 | P36222 | Chitinase-3-like protein 1 | chr1 | GO:0070555 | Not Cancer Driver | No | 66 | 0.172 | 24 | 5 | 0.208 | 0 |
| CITED1_ENST00000246139 | CITED1 | Q99966 | Cbp/p300-interacting transactivator 1 | chrX | GO:0070555 | Not Cancer Driver | No | 24 | 0.124 | 166 | 21 | 0.127 | 0 |
| CX3CL1 | CX3CL1 | P78423 | Fractalkine | chr16 | GO:0070555 | Not Cancer Driver | No | 66 | 0.166 | 259 | 44 | 0.17 | 0 |
| CXCL8 | CXCL8 | P10145 | Interleukin-8 | chr4 | GO:0070555 | Not Cancer Driver | No | 17 | 0.172 | 0 | 0 | 0.0 | 0 |
| CYBA | CYBA | P13498 | Cytochrome b-245 light chain | chr16 | GO:0070555 | Not Cancer Driver | No | 26 | 0.133 | 66 | 2 | 0.03 | 12 |
| DAB2IP_ENST00000408936 | DAB2IP | Q5VWQ8 | Disabled homolog 2-interacting protein | chr9 | GO:0070555 | Not Cancer Driver | No | 131 | 0.11 | 681 | 68 | 0.1 | 0 |
| EDN1 | EDN1 | P05305 | Endothelin-1 | chr6 | GO:0070555 | Not Cancer Driver | No | 37 | 0.175 | 97 | 20 | 0.206 | 3 |
| EPO | EPO | P01588 | Erythropoietin | chr7 | GO:0070555 | Not Cancer Driver | No | 27 | 0.14 | 9 | 1 | 0.111 | 1 |
| FGB | FGB | P02675 | Fibrinogen beta chain | chr4 | GO:0070555 | Not Cancer Driver | No | 89 | 0.181 | 143 | 29 | 0.203 | 7 |
| FGG | FGG | P02679 | Fibrinogen gamma chain | chr4 | GO:0070555 | Not Cancer Driver | No | 81 | 0.179 | 53 | 8 | 0.151 | 8 |
| GBP1 | GBP1 | P32455 | Guanylate-binding protein 1 | chr1 | GO:0070555 | Not Cancer Driver | No | 92 | 0.155 | 166 | 27 | 0.163 | 0 |
| GBP2 | GBP2 | P32456 | Guanylate-binding protein 2 | chr1 | GO:0070555 | Not Cancer Driver | No | 75 | 0.127 | 134 | 15 | 0.112 | 0 |
| GBP3 | GBP3 | Q9H0R5 | Guanylate-binding protein 3 | chr1 | GO:0070555 | Not Cancer Driver | No | 76 | 0.128 | 128 | 15 | 0.117 | 0 |
| GCLC | GCLC | P48506 | Glutamate--cysteine ligase catalytic subunit | chr6 | GO:0070555 | Not Cancer Driver | No | 73 | 0.115 | 167 | 18 | 0.108 | 3 |
| GHR_ENST00000612382 | GHR | P10912 | Growth hormone receptor | chr5 | GO:0070555 | Not Cancer Driver | No | 173 | 0.271 | 229 | 66 | 0.288 | 19 |
| HAS2 | HAS2 | Q92819 | Hyaluronan synthase 2 | chr8 | GO:0070555 | Not Cancer Driver | No | 100 | 0.181 | 17 | 7 | 0.412 | 0 |
| HDAC4 | HDAC4 | P56524 | Histone deacetylase 4 | chr2 | GO:0070555 | Not Cancer Driver | No | 182 | 0.168 | 749 | 132 | 0.176 | 0 |
| HES1 | HES1 | Q14469 | Transcription factor HES-1 | chr3 | GO:0070555 | Not Cancer Driver | No | 37 | 0.132 | 226 | 32 | 0.142 | 0 |
| HIF1A_ENST00000337138 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | GO:0070555 | Census | Yes | 118 | 0.143 | 435 | 51 | 0.117 | 0 |
| HYAL1_ENST00000395144 | HYAL1 | Q12794 | Hyaluronidase-1 | chr3 | GO:0070555 | Not Cancer Driver | No | 47 | 0.108 | 9 | 0 | 0.0 | 1 |
| HYAL2_ENST00000357750 | HYAL2 | Q12891 | Hyaluronidase-2 | chr3 | GO:0070555 | Not Cancer Driver | No | 52 | 0.11 | 8 | 1 | 0.125 | 0 |
| HYAL3 | HYAL3 | O43820 | Hyaluronidase-3 | chr3 | GO:0070555 | Not Cancer Driver | No | 48 | 0.115 | 10 | 0 | 0.0 | 0 |
| IGBP1_ENST00000356413 | IGBP1 | P78318 | Immunoglobulin-binding protein 1 | chrX | GO:0070555 | Not Cancer Driver | No | 51 | 0.15 | 193 | 28 | 0.145 | 0 |
| IL17A | IL17A | Q16552 | Interleukin-17A | chr6 | GO:0070555 | Not Cancer Driver | No | 52 | 0.335 | 56 | 21 | 0.375 | 0 |
| IL1B | IL1B | P01584 | Interleukin-1 beta | chr2 | GO:0070555 | Not Cancer Driver | No | 39 | 0.145 | 16 | 3 | 0.188 | 0 |
| IL1R1 | IL1R1 | P14778 | Interleukin-1 receptor type 1 | chr2 | GO:0070555 | Not Cancer Driver | No | 77 | 0.135 | 59 | 8 | 0.136 | 0 |
| INHBB | INHBB | P09529 | Inhibin beta B chain | chr2 | GO:0070555 | Not Cancer Driver | No | 61 | 0.15 | 98 | 5 | 0.051 | 0 |
| IRAK1 | IRAK1 | P51617 | Interleukin-1 receptor-associated kinase 1 | chrX | GO:0070555 | Compendium | Yes | 71 | 0.1 | 337 | 39 | 0.116 | 0 |
| IRAK2 | IRAK2 | O43187 | Interleukin-1 receptor-associated kinase-like 2 | chr3 | GO:0070555 | Not Cancer Driver | No | 84 | 0.134 | 202 | 32 | 0.158 | 0 |
| IRAK3 | IRAK3 | Q9Y616 | Interleukin-1 receptor-associated kinase 3 | chr12 | GO:0070555 | Not Cancer Driver | No | 103 | 0.173 | 79 | 14 | 0.177 | 0 |
| KLF2 | KLF2 | Q9Y5W3 | Krueppel-like factor 2 | chr19 | GO:0070555 | Not Cancer Driver | No | 13 | 0.037 | 280 | 4 | 0.014 | 0 |
| KMO | KMO | O15229 | Kynurenine 3-monooxygenase | chr1 | GO:0070555 | Not Cancer Driver | No | 77 | 0.158 | 0 | 0 | 0.0 | 0 |
| LGALS9 | LGALS9 | O00182 | Galectin-9 | chr17 | GO:0070555 | Not Cancer Driver | No | 54 | 0.152 | 65 | 16 | 0.246 | 0 |
| MAPK11 | MAPK11 | Q15759 | Mitogen-activated protein kinase 11 | chr22 | GO:0070555 | Not Cancer Driver | No | 23 | 0.063 | 64 | 2 | 0.031 | 0 |
| MAPK13 | MAPK13 | O15264 | Mitogen-activated protein kinase 13 | chr6 | GO:0070555 | Not Cancer Driver | No | 51 | 0.14 | 50 | 15 | 0.3 | 0 |
| MMP2 | MMP2 | P08253 | 72 kDa type IV collagenase | chr16 | GO:0070555 | Not Cancer Driver | No | 123 | 0.186 | 29 | 6 | 0.207 | 2 |
| MTHFR_ENST00000376590 | MTHFR | P42898 | Methylenetetrahydrofolate reductase | chr1 | GO:0070555 | Not Cancer Driver | No | 95 | 0.145 | 125 | 22 | 0.176 | 53 |
| MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | GO:0070555 | Census, Compendium | Yes | 80 | 0.182 | 299 | 46 | 0.154 | 0 |
| MYD88_ENST00000396334 | MYD88 | Q99836 | Myeloid differentiation primary response protein MyD88 | chr3 | GO:0070555 | Census, Compendium | Yes | 37 | 0.125 | 47 | 1 | 0.021 | 2 |
| MYLK3 | MYLK3 | Q32MK0 | Myosin light chain kinase 3 | chr16 | GO:0070555 | Not Cancer Driver | No | 163 | 0.199 | 469 | 83 | 0.177 | 0 |
| NFKB1_ENST00000505458 | NFKB1 | P19838 | Nuclear factor NF-kappa-B p105 subunit | chr4 | GO:0070555 | Not Cancer Driver | No | 104 | 0.107 | 344 | 38 | 0.11 | 0 |
| NKX3-1 | NKX3-1 | Q99801 | Homeobox protein Nkx-3.1 | chr8 | GO:0070555 | Not Cancer Driver | No | 35 | 0.15 | 171 | 16 | 0.094 | 0 |
| NLRP7_ENST00000590030 | NLRP7 | Q8WX94 | NACHT, LRR and PYD domains-containing protein 7 | chr19 | GO:0070555 | Not Cancer Driver | No | 300 | 0.306 | 71 | 20 | 0.282 | 9 |
| NR1D1 | NR1D1 | P20393 | Nuclear receptor subfamily 1 group D member 1 | chr17 | GO:0070555 | Not Cancer Driver | No | 81 | 0.132 | 348 | 49 | 0.141 | 0 |
| PCK1 | PCK1 | P35558 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | chr20 | GO:0070555 | Not Cancer Driver | No | 142 | 0.228 | 110 | 28 | 0.255 | 1 |
| PCSK1 | PCSK1 | P29120 | Neuroendocrine convertase 1 | chr5 | GO:0070555 | Not Cancer Driver | No | 139 | 0.185 | 336 | 61 | 0.182 | 2 |
| PRKCA | PRKCA | P17252 | Protein kinase C alpha type | chr17 | GO:0070555 | Not Cancer Driver | No | 94 | 0.14 | 154 | 22 | 0.143 | 0 |
| PRKCI | PRKCI | P41743 | Protein kinase C iota type | chr3 | GO:0070555 | Not Cancer Driver | No | 110 | 0.185 | 120 | 16 | 0.133 | 0 |
| PTGIS | PTGIS | Q16647 | Prostacyclin synthase | chr20 | GO:0070555 | Not Cancer Driver | No | 102 | 0.204 | 18 | 3 | 0.167 | 0 |
| PYCARD | PYCARD | Q9ULZ3 | Apoptosis-associated speck-like protein containing a CARD | chr16 | GO:0070555 | Not Cancer Driver | No | 16 | 0.082 | 39 | 4 | 0.103 | 0 |
| RBMX | RBMX | P38159 | RNA-binding motif protein, X chromosome | chrX | GO:0070555 | Not Cancer Driver | No | 82 | 0.21 | 380 | 81 | 0.213 | 0 |
| RC3H1_ENST00000258349 | RC3H1 | Q5TC82 | Roquin-1 | chr1 | GO:0070555 | Not Cancer Driver | No | 158 | 0.139 | 796 | 115 | 0.144 | 0 |
| RELA | RELA | Q04206 | Transcription factor p65 | chr11 | GO:0070555 | Compendium | Yes | 75 | 0.136 | 400 | 48 | 0.12 | 0 |
| RIPK2 | RIPK2 | O43353 | Receptor-interacting serine/threonine-protein kinase 2 | chr8 | GO:0070555 | Not Cancer Driver | No | 63 | 0.117 | 143 | 20 | 0.14 | 0 |
| RORA_ENST00000335670 | RORA | P35398 | Nuclear receptor ROR-alpha | chr15 | GO:0070555 | Not Cancer Driver | No | 57 | 0.109 | 182 | 17 | 0.093 | 4 |
| SELE | SELE | P16581 | E-selectin | chr1 | GO:0070555 | Not Cancer Driver | No | 137 | 0.225 | 12 | 0 | 0.0 | 0 |
| SFRP1 | SFRP1 | Q8N474 | Secreted frizzled-related protein 1 | chr8 | GO:0070555 | Not Cancer Driver | No | 40 | 0.127 | 39 | 7 | 0.179 | 0 |
| SIRPA_ENST00000400068 | SIRPA | P78324 | Tyrosine-protein phosphatase non-receptor type substrate 1 | chr20 | GO:0070555 | Census, Compendium | Yes | 96 | 0.19 | 281 | 51 | 0.181 | 0 |
| SLC30A8 | SLC30A8 | Q8IWU4 | Zinc transporter 8 | chr8 | GO:0070555 | Not Cancer Driver | No | 115 | 0.312 | 25 | 9 | 0.36 | 0 |
| SMPD1 | SMPD1 | P17405 | Sphingomyelin phosphodiesterase | chr11 | GO:0070555 | Not Cancer Driver | No | 93 | 0.147 | 51 | 4 | 0.078 | 111 |
| SNCA_ENST00000506244 | SNCA | P37840 | Alpha-synuclein | chr4 | GO:0070555 | Not Cancer Driver | No | 21 | 0.15 | 107 | 13 | 0.121 | 5 |
| SOX9 | SOX9 | P48436 | Transcription factor SOX-9 | chr17 | GO:0070555 | Compendium | Yes | 86 | 0.169 | 495 | 82 | 0.166 | 18 |
| SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0070555 | Census | Yes | 53 | 0.099 | 130 | 11 | 0.085 | 1 |
| TAF9 | TAF9 | Q16594 | Transcription initiation factor TFIID subunit 9 | chr5 | GO:0070555 | Not Cancer Driver | No | 25 | 0.095 | 203 | 19 | 0.094 | 0 |
| TANK | TANK | Q92844 | TRAF family member-associated NF-kappa-B activator | chr2 | GO:0070555 | Not Cancer Driver | No | 42 | 0.099 | 302 | 26 | 0.086 | 0 |
| TNFRSF11A | TNFRSF11A | Q9Y6Q6 | Tumor necrosis factor receptor superfamily member 11A | chr18 | GO:0070555 | Not Cancer Driver | No | 70 | 0.114 | 285 | 33 | 0.116 | 0 |
| TRAF6_ENST00000348124 | TRAF6 | Q9Y4K3 | TNF receptor-associated factor 6 | chr11 | GO:0070555 | Not Cancer Driver | No | 67 | 0.128 | 62 | 7 | 0.113 | 0 |
| TRIM63 | TRIM63 | Q969Q1 | E3 ubiquitin-protein ligase TRIM63 | chr1 | GO:0070555 | Not Cancer Driver | No | 47 | 0.133 | 71 | 13 | 0.183 | 0 |
| UPF1 | UPF1 | Q92900 | Regulator of nonsense transcripts 1 | chr19 | GO:0070555 | Not Cancer Driver | No | 146 | 0.129 | 329 | 36 | 0.109 | 0 |
| USP10_ENST00000219473 | USP10 | Q14694 | Ubiquitin carboxyl-terminal hydrolase 10 | chr16 | GO:0070555 | Not Cancer Driver | No | 92 | 0.115 | 425 | 49 | 0.115 | 0 |
| XCL1 | XCL1 | P47992 | Lymphotactin | chr1 | GO:0070555 | Not Cancer Driver | No | 28 | 0.246 | 35 | 11 | 0.314 | 0 |
| XCL2 | XCL2 | Q9UBD3 | Cytokine SCM-1 beta | chr1 | GO:0070555 | Not Cancer Driver | No | 20 | 0.175 | 35 | 5 | 0.143 | 0 |
| YTHDC2 | YTHDC2 | Q9H6S0 | 3'-5' RNA helicase YTHDC2 | chr5 | GO:0070555 | Not Cancer Driver | No | 163 | 0.114 | 439 | 48 | 0.109 | 0 |
| YY1 | YY1 | P25490 | Transcriptional repressor protein YY1 | chr14 | GO:0070555 | Not Cancer Driver | No | 37 | 0.089 | 336 | 26 | 0.077 | 2 |
| ZC3H12A | ZC3H12A | Q5D1E8 | Endoribonuclease ZC3H12A | chr1 | GO:0070555 | Not Cancer Driver | No | 90 | 0.15 | 396 | 44 | 0.111 | 0 |