Total number of protein in "GO:0070534" GO term: 44
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ARIH2 | ARIH2 | O95376 | E3 ubiquitin-protein ligase ARIH2 | chr3 | GO:0070534 | Not Cancer Driver | No | 64 | 0.13 | 85 | 11 | 0.129 | 0 |
| BFAR | BFAR | Q9NZS9 | Bifunctional apoptosis regulator | chr16 | GO:0070534 | Not Cancer Driver | No | 56 | 0.124 | 30 | 1 | 0.033 | 0 |
| HECTD1 | HECTD1 | Q9ULT8 | E3 ubiquitin-protein ligase HECTD1 | chr14 | GO:0070534 | Not Cancer Driver | No | 274 | 0.105 | 991 | 108 | 0.109 | 0 |
| ITCH | ITCH | Q96J02 | E3 ubiquitin-protein ligase Itchy homolog | chr20 | GO:0070534 | Not Cancer Driver | No | 95 | 0.105 | 335 | 42 | 0.125 | 0 |
| MAGEL2 | MAGEL2 | Q9UJ55 | MAGE-like protein 2 | chr15 | GO:0070534 | Not Cancer Driver | No | 178 | 0.143 | 1010 | 118 | 0.117 | 0 |
| NEDD4 | NEDD4 | P46934 | E3 ubiquitin-protein ligase NEDD4 | chr15 | GO:0070534 | Not Cancer Driver | No | 150 | 0.114 | 711 | 79 | 0.111 | 0 |
| PELI1 | PELI1 | Q96FA3 | E3 ubiquitin-protein ligase pellino homolog 1 | chr2 | GO:0070534 | Not Cancer Driver | No | 47 | 0.112 | 167 | 17 | 0.102 | 0 |
| PELI3 | PELI3 | Q8N2H9 | E3 ubiquitin-protein ligase pellino homolog 3 | chr11 | GO:0070534 | Not Cancer Driver | No | 48 | 0.102 | 216 | 25 | 0.116 | 0 |
| PRKN | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | GO:0070534 | Not Cancer Driver | No | 110 | 0.237 | 78 | 15 | 0.192 | 31 |
| PRPF19 | PRPF19 | Q9UMS4 | Pre-mRNA-processing factor 19 | chr11 | GO:0070534 | Not Cancer Driver | No | 71 | 0.141 | 109 | 16 | 0.147 | 0 |
| RNF115 | RNF115 | Q9Y4L5 | E3 ubiquitin-protein ligase RNF115 | chr1 | GO:0070534 | Not Cancer Driver | No | 30 | 0.099 | 136 | 14 | 0.103 | 0 |
| RNF126 | RNF126 | Q9BV68 | E3 ubiquitin-protein ligase RNF126 | chr19 | GO:0070534 | Not Cancer Driver | No | 33 | 0.106 | 182 | 22 | 0.121 | 0 |
| RNF135 | RNF135 | Q8IUD6 | E3 ubiquitin-protein ligase RNF135 | chr17 | GO:0070534 | Not Cancer Driver | No | 40 | 0.093 | 139 | 11 | 0.079 | 0 |
| RNF152 | RNF152 | Q8N8N0 | E3 ubiquitin-protein ligase RNF152 | chr18 | GO:0070534 | Not Cancer Driver | No | 61 | 0.3 | 34 | 11 | 0.324 | 0 |
| RNF168 | RNF168 | Q8IYW5 | E3 ubiquitin-protein ligase RNF168 | chr3 | GO:0070534 | Not Cancer Driver | No | 77 | 0.135 | 471 | 66 | 0.14 | 0 |
| RNF186 | RNF186 | Q9NXI6 | E3 ubiquitin-protein ligase RNF186 | chr1 | GO:0070534 | Not Cancer Driver | No | 27 | 0.119 | 11 | 3 | 0.273 | 0 |
| RNF213 | RNF213 | Q63HN8 | E3 ubiquitin-protein ligase RNF213 | chr17 | GO:0070534 | Census, Compendium | Yes | 560 | 0.108 | 623 | 75 | 0.12 | 3 |
| RNF4 | RNF4 | P78317 | E3 ubiquitin-protein ligase RNF4 | chr4 | GO:0070534 | Not Cancer Driver | No | 14 | 0.074 | 117 | 7 | 0.06 | 0 |
| RNF5 | RNF5 | Q99942 | E3 ubiquitin-protein ligase RNF5 | chr6 | GO:0070534 | Not Cancer Driver | No | 17 | 0.094 | 69 | 3 | 0.043 | 0 |
| RNF8 | RNF8 | O76064 | E3 ubiquitin-protein ligase RNF8 | chr6 | GO:0070534 | Not Cancer Driver | No | 56 | 0.115 | 226 | 29 | 0.128 | 0 |
| STUB1 | STUB1 | Q9UNE7 | E3 ubiquitin-protein ligase CHIP | chr16 | GO:0070534 | Not Cancer Driver | No | 35 | 0.116 | 112 | 14 | 0.125 | 12 |
| TRAF1 | TRAF1 | Q13077 | TNF receptor-associated factor 1 | chr9 | GO:0070534 | Not Cancer Driver | No | 51 | 0.123 | 63 | 9 | 0.143 | 0 |
| TRAF2 | TRAF2 | Q12933 | TNF receptor-associated factor 2 | chr9 | GO:0070534 | Not Cancer Driver | No | 63 | 0.126 | 4 | 1 | 0.25 | 0 |
| TRAF3IP2_ENST00000392556 | TRAF3IP2 | O43734 | E3 ubiquitin ligase TRAF3IP2 | chr6 | GO:0070534 | Not Cancer Driver | No | 59 | 0.103 | 410 | 39 | 0.095 | 2 |
| TRAF3_ENST00000392745 | TRAF3 | Q13114 | TNF receptor-associated factor 3 | chr14 | GO:0070534 | Compendium | Yes | 61 | 0.107 | 101 | 9 | 0.089 | 1 |
| TRAF5_ENST00000336184 | TRAF5 | O00463 | TNF receptor-associated factor 5 | chr1 | GO:0070534 | Not Cancer Driver | No | 61 | 0.11 | 59 | 5 | 0.085 | 0 |
| TRAF6_ENST00000348124 | TRAF6 | Q9Y4K3 | TNF receptor-associated factor 6 | chr11 | GO:0070534 | Not Cancer Driver | No | 67 | 0.128 | 62 | 7 | 0.113 | 0 |
| TRIM21 | TRIM21 | P19474 | E3 ubiquitin-protein ligase TRIM21 | chr11 | GO:0070534 | Not Cancer Driver | No | 85 | 0.179 | 49 | 7 | 0.143 | 0 |
| TRIM27 | TRIM27 | P14373 | Zinc finger protein RFP | chr6 | GO:0070534 | Census | Yes | 59 | 0.115 | 87 | 11 | 0.126 | 0 |
| TRIM5 | TRIM5 | Q9C035 | Tripartite motif-containing protein 5 | chr11 | GO:0070534 | Not Cancer Driver | No | 71 | 0.144 | 77 | 11 | 0.143 | 0 |
| TRIM56 | TRIM56 | Q9BRZ2 | E3 ubiquitin-protein ligase TRIM56 | chr7 | GO:0070534 | Not Cancer Driver | No | 110 | 0.146 | 217 | 36 | 0.166 | 0 |
| UBE2B | UBE2B | P63146 | Ubiquitin-conjugating enzyme E2 B | chr5 | GO:0070534 | Not Cancer Driver | No | 13 | 0.086 | 68 | 6 | 0.088 | 0 |
| UBE2D4 | UBE2D4 | Q9Y2X8 | Ubiquitin-conjugating enzyme E2 D4 | chr7 | GO:0070534 | Not Cancer Driver | No | 13 | 0.088 | 21 | 1 | 0.048 | 0 |
| UBE2E2_ENST00000425792 | UBE2E2 | Q96LR5 | Ubiquitin-conjugating enzyme E2 E2 | chr3 | GO:0070534 | Not Cancer Driver | No | 28 | 0.139 | 90 | 15 | 0.167 | 0 |
| UBE2E3_ENST00000602710 | UBE2E3 | Q969T4 | Ubiquitin-conjugating enzyme E2 E3 | chr2 | GO:0070534 | Not Cancer Driver | No | 34 | 0.164 | 97 | 14 | 0.144 | 0 |
| UBE2G1 | UBE2G1 | P62253 | Ubiquitin-conjugating enzyme E2 G1 | chr17 | GO:0070534 | Not Cancer Driver | No | 9 | 0.053 | 39 | 2 | 0.051 | 0 |
| UBE2N | UBE2N | P61088 | Ubiquitin-conjugating enzyme E2 N | chr12 | GO:0070534 | Not Cancer Driver | No | 25 | 0.164 | 24 | 3 | 0.125 | 0 |
| UBE2O | UBE2O | Q9C0C9 | (E3-independent) E2 ubiquitin-conjugating enzyme | chr17 | GO:0070534 | Not Cancer Driver | No | 129 | 0.1 | 716 | 68 | 0.095 | 0 |
| UBE2S | UBE2S | Q16763 | Ubiquitin-conjugating enzyme E2 S | chr19 | GO:0070534 | Not Cancer Driver | No | 25 | 0.113 | 102 | 12 | 0.118 | 0 |
| UBE2T | UBE2T | Q9NPD8 | Ubiquitin-conjugating enzyme E2 T | chr1 | GO:0070534 | Not Cancer Driver | No | 12 | 0.061 | 97 | 9 | 0.093 | 1 |
| UBE2V1_ENST00000371674 | UBE2V1 | Q13404 | Ubiquitin-conjugating enzyme E2 variant 1 | chr20 | GO:0070534 | Not Cancer Driver | No | 19 | 0.129 | 51 | 5 | 0.098 | 0 |
| UBE2V2 | UBE2V2 | Q15819 | Ubiquitin-conjugating enzyme E2 variant 2 | chr8 | GO:0070534 | Not Cancer Driver | No | 22 | 0.152 | 76 | 12 | 0.158 | 0 |
| WWP2 | WWP2 | O00308 | NEDD4-like E3 ubiquitin-protein ligase WWP2 | chr16 | GO:0070534 | Not Cancer Driver | No | 112 | 0.129 | 422 | 57 | 0.135 | 0 |
| ZFP91 | ZFP91 | Q96JP5 | E3 ubiquitin-protein ligase ZFP91 | chr11 | GO:0070534 | Not Cancer Driver | No | 85 | 0.149 | 383 | 55 | 0.144 | 0 |