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Total number of protein in "GO:0070372" GO term:  98

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0070372 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACE2 ACE2 Q9BYF1 Angiotensin-converting enzyme 2 chrX GO:0070372 Not Cancer Driver No 104 0.129 68 5 0.074 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0070372 Not Cancer Driver No 39 0.16 92 21 0.228 1
APIP APIP Q96GX9 Methylthioribulose-1-phosphate dehydratase chr11 GO:0070372 Not Cancer Driver No 24 0.099 26 1 0.038 0
ARHGEF5 ARHGEF5 Q12774 Rho guanine nucleotide exchange factor 5 chr7 GO:0070372 Not Cancer Driver No 170 0.106 1141 127 0.111 0
ATF3_ENST00000366987 ATF3 P18847 Cyclic AMP-dependent transcription factor ATF-3 chr1 GO:0070372 Not Cancer Driver No 23 0.127 118 14 0.119 0
BTN2A2 BTN2A2 Q8WVV5 Butyrophilin subfamily 2 member A2 chr6 GO:0070372 Not Cancer Driver No 92 0.176 24 2 0.083 0
C1QL4 C1QL4 Q86Z23 Complement C1q-like protein 4 chr12 GO:0070372 Not Cancer Driver No 19 0.08 101 5 0.05 0
C3orf33 C3orf33 Q6P1S2 Protein C3orf33 chr3 GO:0070372 Not Cancer Driver No 30 0.102 23 0 0.0 0
CCN1 CCN1 O00622 CCN family member 1 chr1 GO:0070372 Not Cancer Driver No 33 0.087 12 0 0.0 0
CEACAM1 CEACAM1 P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 chr19 GO:0070372 Not Cancer Driver No 64 0.122 241 25 0.104 0
CHRNA10 CHRNA10 Q9GZZ6 Neuronal acetylcholine receptor subunit alpha-10 chr11 GO:0070372 Not Cancer Driver No 65 0.144 34 5 0.147 0
CHRNA9 CHRNA9 Q9UGM1 Neuronal acetylcholine receptor subunit alpha-9 chr4 GO:0070372 Not Cancer Driver No 76 0.159 23 6 0.261 0
CNKSR3 CNKSR3 Q6P9H4 Connector enhancer of kinase suppressor of ras 3 chr6 GO:0070372 Not Cancer Driver No 72 0.13 269 43 0.16 0
CRYBA1 CRYBA1 P05813 Beta-crystallin A3 chr17 GO:0070372 Not Cancer Driver No 29 0.135 52 11 0.212 0
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 GO:0070372 Not Cancer Driver No 41 0.091 18 1 0.056 0
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0070372 Not Cancer Driver No 144 0.187 680 125 0.184 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0070372 Not Cancer Driver No 131 0.11 681 68 0.1 0
DLG1_ENST00000419354 DLG1 Q12959 Disks large homolog 1 chr3 GO:0070372 Not Cancer Driver No 120 0.133 460 67 0.146 0
DUPD1 DUSP29 Q68J44 Dual specificity phosphatase 29 chr10 GO:0070372 Not Cancer Driver No 47 0.214 55 7 0.127 0
DUSP10 DUSP10 Q9Y6W6 Dual specificity protein phosphatase 10 chr1 GO:0070372 Not Cancer Driver No 81 0.168 135 24 0.178 0
DUSP26 DUSP26 Q9BV47 Dual specificity protein phosphatase 26 chr8 GO:0070372 Not Cancer Driver No 56 0.265 14 6 0.429 0
DUSP3 DUSP3 P51452 Dual specificity protein phosphatase 3 chr17 GO:0070372 Not Cancer Driver No 21 0.114 4 1 0.25 0
DUSP4 DUSP4 Q13115 Dual specificity protein phosphatase 4 chr8 GO:0070372 Not Cancer Driver No 43 0.109 63 9 0.143 0
DUSP6 DUSP6 Q16828 Dual specificity protein phosphatase 6 chr12 GO:0070372 Not Cancer Driver No 43 0.113 39 3 0.077 4
DUSP9 DUSP9 Q99956 Dual specificity protein phosphatase 9 chrX GO:0070372 Not Cancer Driver No 40 0.104 109 12 0.11 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0070372 Census, Compendium Yes 444 0.367 223 35 0.157 1
EIF3A EIF3A Q14152 Eukaryotic translation initiation factor 3 subunit A chr10 GO:0070372 Not Cancer Driver No 181 0.131 835 130 0.156 0
EMILIN1 EMILIN1 Q9Y6C2 EMILIN-1 chr2 GO:0070372 Not Cancer Driver No 125 0.123 669 69 0.103 0
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 GO:0070372 Compendium Yes 171 0.175 187 39 0.209 3
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0070372 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHA7 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 GO:0070372 Census, Compendium Yes 280 0.281 71 15 0.211 0
EPHB1 EPHB1 P54762 Ephrin type-B receptor 1 chr3 GO:0070372 Not Cancer Driver No 316 0.321 67 17 0.254 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0070372 Not Cancer Driver No 186 0.176 119 17 0.143 7
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0070372 Census, Compendium Yes 275 0.219 314 41 0.131 1
ERRFI1 ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 chr1 GO:0070372 Not Cancer Driver No 55 0.119 297 37 0.125 0
EZR EZR P15311 Ezrin chr6 GO:0070372 Census Yes 66 0.113 295 35 0.119 0
FAM83D FAM83D Q9H4H8 Protein FAM83D chr20 GO:0070372 Not Cancer Driver No 70 0.12 273 29 0.106 0
FBLN1 FBLN1 P23142 Fibulin-1 chr22 GO:0070372 Compendium Yes 122 0.174 22 3 0.136 0
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 GO:0070372 Census, Compendium Yes 238 0.29 228 44 0.193 72
FLCN FLCN Q8NFG4 Folliculin chr17 GO:0070372 Census, Compendium Yes 59 0.102 157 19 0.121 5
FN1 FN1 P02751 Fibronectin chr2 GO:0070372 Compendium Yes 394 0.159 1243 185 0.149 8
FRS2 FRS2 Q8WU20 Fibroblast growth factor receptor substrate 2 chr12 GO:0070372 Not Cancer Driver No 69 0.136 415 58 0.14 0
GBP1 GBP1 P32455 Guanylate-binding protein 1 chr1 GO:0070372 Not Cancer Driver No 92 0.155 166 27 0.163 0
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0070372 Not Cancer Driver No 65 0.173 13 5 0.385 0
GSTP1_ENST00000642444 GSTP1 P09211 Glutathione S-transferase P chr11 GO:0070372 Not Cancer Driver No 32 0.152 0 0 0.0 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0070372 Not Cancer Driver No 39 0.145 16 3 0.188 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0070372 Not Cancer Driver No 26 0.13 58 11 0.19 0
LIF LIF P15018 Leukemia inhibitory factor chr22 GO:0070372 Not Cancer Driver No 25 0.124 0 0 0.0 0
LMO3_ENST00000534946 LMO3 Q8TAP4 LIM domain only protein 3 chr12 GO:0070372 Not Cancer Driver No 30 0.207 1 0 0.0 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0070372 Census Yes 95 0.186 84 12 0.143 0
NDRG2 NDRG2 Q9UN36 Protein NDRG2 chr14 GO:0070372 Not Cancer Driver No 45 0.121 111 8 0.072 0
NEK10_ENST00000429845 NEK10 Q6ZWH5 Serine/threonine-protein kinase Nek10 chr3 GO:0070372 Not Cancer Driver No 213 0.182 281 60 0.214 0
NLRP12_ENST00000324134 NLRP12 P59046 NACHT, LRR and PYD domains-containing protein 12 chr19 GO:0070372 Not Cancer Driver No 310 0.292 116 43 0.371 0
NLRP6 NLRP6 P59044 NACHT, LRR and PYD domains-containing protein 6 chr11 GO:0070372 Not Cancer Driver No 106 0.119 203 28 0.138 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:0070372 Not Cancer Driver No 37 0.136 4 1 0.25 0
PIN1 PIN1 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 chr19 GO:0070372 Not Cancer Driver No 17 0.104 115 12 0.104 0
PKHD1 PKHD1 P08F94 Fibrocystin chr6 GO:0070372 Not Cancer Driver No 778 0.191 413 81 0.196 93
PRMT5 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 GO:0070372 Not Cancer Driver No 83 0.13 72 6 0.083 0
PSCA PSCA O43653 Prostate stem cell antigen chr8 GO:0070372 Not Cancer Driver No 9 0.079 0 0 0.0 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0070372 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:0070372 Not Cancer Driver No 49 0.113 140 25 0.179 0
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:0070372 Not Cancer Driver No 57 0.137 120 14 0.117 0
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:0070372 Census, Compendium Yes 73 0.123 192 25 0.13 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0070372 Census, Compendium Yes 315 0.241 462 107 0.232 0
PTPRR PTPRR Q15256 Receptor-type tyrosine-protein phosphatase R chr12 GO:0070372 Not Cancer Driver No 172 0.262 73 28 0.384 0
RANBP9 RANBP9 Q96S59 Ran-binding protein 9 chr6 GO:0070372 Not Cancer Driver No 73 0.1 413 30 0.073 0
RASGRP1 RASGRP1 O95267 RAS guanyl-releasing protein 1 chr15 GO:0070372 Not Cancer Driver No 96 0.12 191 12 0.063 1
RGS14 RGS14 O43566 Regulator of G-protein signaling 14 chr5 GO:0070372 Not Cancer Driver No 57 0.101 309 37 0.12 0
ROS1 ROS1 P08922 Proto-oncogene tyrosine-protein kinase ROS chr6 GO:0070372 Census Yes 498 0.212 191 55 0.288 0
RPS6KA6_ENST00000262752 RPS6KA6 Q9UK32 Ribosomal protein S6 kinase alpha-6 chrX GO:0070372 Not Cancer Driver No 180 0.242 136 36 0.265 0
RRAS RRAS P10301 Ras-related protein R-Ras chr19 GO:0070372 Not Cancer Driver No 25 0.115 71 6 0.085 0
SEMA6A_ENST00000510263 SEMA6A Q9H2E6 Semaphorin-6A chr5 GO:0070372 Not Cancer Driver No 136 0.132 456 72 0.158 0
SIRPA_ENST00000400068 SIRPA P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 GO:0070372 Census, Compendium Yes 96 0.19 281 51 0.181 0
SLC9A3R1 SLC9A3R1 O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 chr17 GO:0070372 Not Cancer Driver No 19 0.053 318 16 0.05 4
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0070372 Census, Compendium Yes 198 0.359 195 17 0.087 8
SPRED1 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 GO:0070372 Not Cancer Driver No 71 0.16 194 35 0.18 2
SPRED2 SPRED2 Q7Z698 Sprouty-related, EVH1 domain-containing protein 2 chr2 GO:0070372 Not Cancer Driver No 73 0.175 228 43 0.189 0
SPRED3_ENST00000586301 SPRED3 Q2MJR0 Sprouty-related, EVH1 domain-containing protein 3 chr19 GO:0070372 Not Cancer Driver No 31 0.076 207 15 0.072 0
SPRY1 SPRY1 O43609 Protein sprouty homolog 1 chr4 GO:0070372 Not Cancer Driver No 46 0.144 168 26 0.155 0
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 GO:0070372 Not Cancer Driver No 46 0.146 169 29 0.172 1
SPRY3 SPRY3 O43610 Protein sprouty homolog 3 chrX GO:0070372 Not Cancer Driver No 96 0.333 135 40 0.296 0
SPRY4_ENST00000434127 SPRY4 Q9C004 Protein sprouty homolog 4 chr5 GO:0070372 Not Cancer Driver No 34 0.114 134 20 0.149 7
STYX STYX Q8WUJ0 Serine/threonine/tyrosine-interacting protein chr14 GO:0070372 Not Cancer Driver No 20 0.09 30 2 0.067 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0070372 Census Yes 96 0.151 131 27 0.206 5
SYNJ2BP SYNJ2BP P57105 Synaptojanin-2-binding protein chr14 GO:0070372 Not Cancer Driver No 27 0.186 12 4 0.333 0
TBC1D10C TBC1D10C Q8IV04 Carabin chr11 GO:0070372 Not Cancer Driver No 58 0.13 192 32 0.167 0
TGFBR3_ENST00000525962 TGFBR3 Q03167 Transforming growth factor beta receptor type 3 chr1 GO:0070372 Not Cancer Driver No 129 0.152 268 41 0.153 0
TIMP3 TIMP3 P35625 Metalloproteinase inhibitor 3 chr22 GO:0070372 Not Cancer Driver No 43 0.204 3 1 0.333 5
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0070372 Not Cancer Driver No 292 0.348 0 0 0.0 0
TNFRSF11A TNFRSF11A Q9Y6Q6 Tumor necrosis factor receptor superfamily member 11A chr18 GO:0070372 Not Cancer Driver No 70 0.114 285 33 0.116 0
TNFSF11 TNFSF11 O14788 Tumor necrosis factor ligand superfamily member 11 chr13 GO:0070372 Not Cancer Driver No 52 0.164 56 1 0.018 1
TNIP1_ENST00000522226 TNIP1 Q15025 TNFAIP3-interacting protein 1 chr5 GO:0070372 Not Cancer Driver No 85 0.134 625 83 0.133 0
TRAF7 TRAF7 Q6Q0C0 E3 ubiquitin-protein ligase TRAF7 chr16 GO:0070372 Census Yes 76 0.113 120 14 0.117 4
VRK3_ENST00000594948 VRK3 Q8IV63 Inactive serine/threonine-protein kinase VRK3 chr19 GO:0070372 Not Cancer Driver No 65 0.137 180 18 0.1 0
WNK2 WNK2 Q9Y3S1 Serine/threonine-protein kinase WNK2 chr9 GO:0070372 Census, Compendium Yes 223 0.097 1868 167 0.089 0
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 GO:0070372 Not Cancer Driver No 30 0.122 81 10 0.123 0
ZDHHC17 ZDHHC17 Q8IUH5 Palmitoyltransferase ZDHHC17 chr12 GO:0070372 Not Cancer Driver No 84 0.133 49 9 0.184 0