Total number of protein in "GO:0070302" GO term: 85
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGER_ENST00000375076 | AGER | Q15109 | Advanced glycosylation end product-specific receptor | chr6 | GO:0070302 | Not Cancer Driver | No | 31 | 0.077 | 297 | 21 | 0.071 | 0 |
| AIDA | AIDA | Q96BJ3 | Axin interactor, dorsalization-associated protein | chr1 | GO:0070302 | Not Cancer Driver | No | 36 | 0.118 | 87 | 9 | 0.103 | 0 |
| AMBP | AMBP | P02760 | Protein AMBP | chr9 | GO:0070302 | Not Cancer Driver | No | 57 | 0.162 | 61 | 15 | 0.246 | 0 |
| BMP2 | BMP2 | P12643 | Bone morphogenetic protein 2 | chr20 | GO:0070302 | Not Cancer Driver | No | 73 | 0.184 | 139 | 26 | 0.187 | 0 |
| BMP4 | BMP4 | P12644 | Bone morphogenetic protein 4 | chr14 | GO:0070302 | Not Cancer Driver | No | 86 | 0.211 | 142 | 26 | 0.183 | 5 |
| CAV3 | CAV3 | P56539 | Caveolin-3 | chr3 | GO:0070302 | Not Cancer Driver | No | 27 | 0.179 | 0 | 0 | 0.0 | 25 |
| CYLD | CYLD | Q9NQC7 | Ubiquitin carboxyl-terminal hydrolase CYLD | chr16 | GO:0070302 | Census, Compendium | Yes | 116 | 0.121 | 213 | 31 | 0.146 | 3 |
| DAB2IP_ENST00000408936 | DAB2IP | Q5VWQ8 | Disabled homolog 2-interacting protein | chr9 | GO:0070302 | Not Cancer Driver | No | 131 | 0.11 | 681 | 68 | 0.1 | 0 |
| DACT1 | DACT1 | Q9NYF0 | Dapper homolog 1 | chr14 | GO:0070302 | Not Cancer Driver | No | 163 | 0.195 | 598 | 127 | 0.212 | 1 |
| DLG1_ENST00000419354 | DLG1 | Q12959 | Disks large homolog 1 | chr3 | GO:0070302 | Not Cancer Driver | No | 120 | 0.133 | 460 | 67 | 0.146 | 0 |
| DNAJA1 | DNAJA1 | P31689 | DnaJ homolog subfamily A member 1 | chr9 | GO:0070302 | Not Cancer Driver | No | 37 | 0.093 | 153 | 16 | 0.105 | 0 |
| DUSP1 | DUSP1 | P28562 | Dual specificity protein phosphatase 1 | chr5 | GO:0070302 | Not Cancer Driver | No | 31 | 0.084 | 7 | 0 | 0.0 | 0 |
| DUSP10 | DUSP10 | Q9Y6W6 | Dual specificity protein phosphatase 10 | chr1 | GO:0070302 | Not Cancer Driver | No | 81 | 0.168 | 135 | 24 | 0.178 | 0 |
| DUSP16 | DUSP16 | Q9BY84 | Dual specificity protein phosphatase 16 | chr12 | GO:0070302 | Compendium | Yes | 70 | 0.105 | 273 | 34 | 0.125 | 0 |
| DUSP19 | DUSP19 | Q8WTR2 | Dual specificity protein phosphatase 19 | chr2 | GO:0070302 | Not Cancer Driver | No | 34 | 0.157 | 15 | 5 | 0.333 | 0 |
| DUSP3 | DUSP3 | P51452 | Dual specificity protein phosphatase 3 | chr17 | GO:0070302 | Not Cancer Driver | No | 21 | 0.114 | 4 | 1 | 0.25 | 0 |
| EMC10 | EMC10 | Q5UCC4 | ER membrane protein complex subunit 10 | chr19 | GO:0070302 | Not Cancer Driver | No | 25 | 0.095 | 109 | 15 | 0.138 | 0 |
| EZR | EZR | P15311 | Ezrin | chr6 | GO:0070302 | Census | Yes | 66 | 0.113 | 295 | 35 | 0.119 | 0 |
| F2RL1 | F2RL1 | P55085 | Proteinase-activated receptor 2 | chr5 | GO:0070302 | Not Cancer Driver | No | 55 | 0.139 | 7 | 2 | 0.286 | 0 |
| FKTN_ENST00000602661 | FKTN | O75072 | Ribitol-5-phosphate transferase FKTN | chr9 | GO:0070302 | Not Cancer Driver | No | 51 | 0.111 | 0 | 0 | 0.0 | 10 |
| FOXM1_ENST00000359843 | FOXM1 | Q08050 | Forkhead box protein M1 | chr12 | GO:0070302 | Not Cancer Driver | No | 97 | 0.127 | 601 | 73 | 0.121 | 0 |
| FOXO1 | FOXO1 | Q12778 | Forkhead box protein O1 | chr13 | GO:0070302 | Census, Compendium | Yes | 81 | 0.124 | 584 | 75 | 0.128 | 0 |
| GADD45A | GADD45A | P24522 | Growth arrest and DNA damage-inducible protein GADD45 alpha | chr1 | GO:0070302 | Not Cancer Driver | No | 10 | 0.061 | 39 | 5 | 0.128 | 0 |
| GADD45B | GADD45B | O75293 | Growth arrest and DNA damage-inducible protein GADD45 beta | chr19 | GO:0070302 | Not Cancer Driver | No | 9 | 0.056 | 14 | 0 | 0.0 | 0 |
| GADD45G | GADD45G | O95257 | Growth arrest and DNA damage-inducible protein GADD45 gamma | chr9 | GO:0070302 | Not Cancer Driver | No | 13 | 0.082 | 20 | 2 | 0.1 | 0 |
| GDF6 | GDF6 | Q6KF10 | Growth/differentiation factor 6 | chr8 | GO:0070302 | Not Cancer Driver | No | 91 | 0.2 | 225 | 46 | 0.204 | 14 |
| GPS2 | GPS2 | Q13227 | G protein pathway suppressor 2 | chr17 | GO:0070302 | Not Cancer Driver | No | 29 | 0.089 | 319 | 26 | 0.082 | 0 |
| GSTP1_ENST00000642444 | GSTP1 | P09211 | Glutathione S-transferase P | chr11 | GO:0070302 | Not Cancer Driver | No | 32 | 0.152 | 0 | 0 | 0.0 | 0 |
| HAND2 | HAND2 | P61296 | Heart- and neural crest derivatives-expressed protein 2 | chr4 | GO:0070302 | Not Cancer Driver | No | 47 | 0.217 | 124 | 29 | 0.234 | 0 |
| HDAC3 | HDAC3 | O15379 | Histone deacetylase 3 | chr5 | GO:0070302 | Not Cancer Driver | No | 65 | 0.152 | 61 | 8 | 0.131 | 0 |
| HGF_ENST00000644543 | HGF | P14210 | Hepatocyte growth factor | chr7 | GO:0070302 | Compendium | Yes | 233 | 0.32 | 43 | 16 | 0.372 | 0 |
| HIPK3 | HIPK3 | Q9H422 | Homeodomain-interacting protein kinase 3 | chr11 | GO:0070302 | Not Cancer Driver | No | 128 | 0.105 | 559 | 51 | 0.091 | 0 |
| IGBP1_ENST00000356413 | IGBP1 | P78318 | Immunoglobulin-binding protein 1 | chrX | GO:0070302 | Not Cancer Driver | No | 51 | 0.15 | 193 | 28 | 0.145 | 0 |
| IL1B | IL1B | P01584 | Interleukin-1 beta | chr2 | GO:0070302 | Not Cancer Driver | No | 39 | 0.145 | 16 | 3 | 0.188 | 0 |
| ITCH | ITCH | Q96J02 | E3 ubiquitin-protein ligase Itchy homolog | chr20 | GO:0070302 | Not Cancer Driver | No | 95 | 0.105 | 335 | 42 | 0.125 | 0 |
| KLHL31 | KLHL31 | Q9H511 | Kelch-like protein 31 | chr6 | GO:0070302 | Not Cancer Driver | No | 69 | 0.109 | 32 | 1 | 0.031 | 0 |
| LEP | LEP | P41159 | Leptin | chr7 | GO:0070302 | Not Cancer Driver | No | 29 | 0.174 | 0 | 0 | 0.0 | 2 |
| LGALS9 | LGALS9 | O00182 | Galectin-9 | chr17 | GO:0070302 | Not Cancer Driver | No | 54 | 0.152 | 65 | 16 | 0.246 | 0 |
| MAP3K3_ENST00000361733 | MAP3K3 | Q99759 | Mitogen-activated protein kinase kinase kinase 3 | chr17 | GO:0070302 | Not Cancer Driver | No | 74 | 0.118 | 355 | 44 | 0.124 | 0 |
| MAP3K4 | MAP3K4 | Q9Y6R4 | Mitogen-activated protein kinase kinase kinase 4 | chr6 | GO:0070302 | Not Cancer Driver | No | 261 | 0.162 | 520 | 86 | 0.165 | 0 |
| MAP3K5 | MAP3K5 | Q99683 | Mitogen-activated protein kinase kinase kinase 5 | chr6 | GO:0070302 | Not Cancer Driver | No | 197 | 0.143 | 242 | 29 | 0.12 | 0 |
| MAPK8IP1 | MAPK8IP1 | Q9UQF2 | C-Jun-amino-terminal kinase-interacting protein 1 | chr11 | GO:0070302 | Not Cancer Driver | No | 79 | 0.111 | 444 | 40 | 0.09 | 1 |
| MARVELD3_ENST00000268485 | MARVELD3 | Q96A59 | MARVEL domain-containing protein 3 | chr16 | GO:0070302 | Not Cancer Driver | No | 40 | 0.1 | 179 | 10 | 0.056 | 0 |
| MECOM_ENST00000494292 | MECOM | Q03112 | Histone-lysine N-methyltransferase MECOM | chr3 | GO:0070302 | Census, Compendium | Yes | 287 | 0.233 | 749 | 159 | 0.212 | 3 |
| MEN1 | MEN1 | O00255 | Menin | chr11 | GO:0070302 | Census, Compendium | Yes | 73 | 0.119 | 228 | 15 | 0.066 | 90 |
| MFHAS1 | MFHAS1 | Q9Y4C4 | Malignant fibrous histiocytoma-amplified sequence 1 | chr8 | GO:0070302 | Not Cancer Driver | No | 95 | 0.09 | 98 | 9 | 0.092 | 0 |
| MINK1 | MINK1 | Q8N4C8 | Misshapen-like kinase 1 | chr17 | GO:0070302 | Not Cancer Driver | No | 113 | 0.085 | 740 | 56 | 0.076 | 0 |
| MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | GO:0070302 | Census, Compendium | Yes | 80 | 0.182 | 299 | 46 | 0.154 | 0 |
| NCF1 | NCF1 | P14598 | Neutrophil cytosol factor 1 | chr7 | GO:0070302 | Not Cancer Driver | No | 37 | 0.095 | 181 | 12 | 0.066 | 1 |
| NCOR1 | NCOR1 | O75376 | Nuclear receptor corepressor 1 | chr17 | GO:0070302 | Census, Compendium | Yes | 352 | 0.144 | 2347 | 340 | 0.145 | 0 |
| NPPA | NPPA | P01160 | Natriuretic peptides A | chr1 | GO:0070302 | Not Cancer Driver | No | 32 | 0.212 | 71 | 14 | 0.197 | 1 |
| OPRK1_ENST00000520287 | OPRK1 | P41145 | Kappa-type opioid receptor | chr8 | GO:0070302 | Not Cancer Driver | No | 117 | 0.308 | 18 | 5 | 0.278 | 0 |
| PAFAH1B1 | PAFAH1B1 | P43034 | Platelet-activating factor acetylhydrolase IB subunit beta | chr17 | GO:0070302 | Not Cancer Driver | No | 42 | 0.102 | 82 | 11 | 0.134 | 7 |
| PBK_ENST00000301905 | PBK | Q96KB5 | Lymphokine-activated killer T-cell-originated protein kinase | chr8 | GO:0070302 | Not Cancer Driver | No | 23 | 0.071 | 92 | 6 | 0.065 | 0 |
| PDCD4 | PDCD4 | Q53EL6 | Programmed cell death protein 4 | chr10 | GO:0070302 | Not Cancer Driver | No | 57 | 0.122 | 187 | 32 | 0.171 | 0 |
| PER1 | PER1 | O15534 | Period circadian protein homolog 1 | chr17 | GO:0070302 | Census | Yes | 160 | 0.124 | 948 | 116 | 0.122 | 0 |
| PHLPP1 | PHLPP1 | O60346 | PH domain leucine-rich repeat-containing protein phosphatase 1 | chr18 | GO:0070302 | Not Cancer Driver | No | 134 | 0.078 | 744 | 29 | 0.039 | 0 |
| PINK1 | PINK1 | Q9BXM7 | Serine/threonine-protein kinase PINK1, mitochondrial | chr1 | GO:0070302 | Not Cancer Driver | No | 57 | 0.098 | 99 | 13 | 0.131 | 23 |
| PJA2 | PJA2 | O43164 | E3 ubiquitin-protein ligase Praja-2 | chr5 | GO:0070302 | Not Cancer Driver | No | 80 | 0.113 | 598 | 66 | 0.11 | 0 |
| PPIA | PPIA | P62937 | Peptidyl-prolyl cis-trans isomerase A | chr7 | GO:0070302 | Not Cancer Driver | No | 11 | 0.067 | 24 | 3 | 0.125 | 0 |
| PRKN | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | GO:0070302 | Not Cancer Driver | No | 110 | 0.237 | 78 | 15 | 0.192 | 31 |
| PRMT1 | PRMT1 | Q99873 | Protein arginine N-methyltransferase 1 | chr19 | GO:0070302 | Not Cancer Driver | No | 50 | 0.135 | 18 | 1 | 0.056 | 0 |
| PTPN22 | PTPN22 | Q9Y2R2 | Tyrosine-protein phosphatase non-receptor type 22 | chr1 | GO:0070302 | Not Cancer Driver | No | 141 | 0.175 | 364 | 62 | 0.17 | 4 |
| QARS | QARS1 | P47897 | Glutamine--tRNA ligase | chr3 | GO:0070302 | Not Cancer Driver | No | 101 | 0.13 | 106 | 16 | 0.151 | 4 |
| RASGRP1 | RASGRP1 | O95267 | RAS guanyl-releasing protein 1 | chr15 | GO:0070302 | Not Cancer Driver | No | 96 | 0.12 | 191 | 12 | 0.063 | 1 |
| RELL1_ENST00000314117 | RELL1 | Q8IUW5 | RELT-like protein 1 | chr4 | GO:0070302 | Not Cancer Driver | No | 19 | 0.07 | 201 | 11 | 0.055 | 0 |
| RELL2 | RELL2 | Q8NC24 | RELT-like protein 2 | chr5 | GO:0070302 | Not Cancer Driver | No | 39 | 0.129 | 259 | 37 | 0.143 | 0 |
| SASH1 | SASH1 | O94885 | SAM and SH3 domain-containing protein 1 | chr6 | GO:0070302 | Not Cancer Driver | No | 174 | 0.14 | 1071 | 153 | 0.143 | 7 |
| SERPINB3 | SERPINB3 | P29508 | Serpin B3 | chr18 | GO:0070302 | Not Cancer Driver | No | 142 | 0.364 | 47 | 28 | 0.596 | 0 |
| SFRP1 | SFRP1 | Q8N474 | Secreted frizzled-related protein 1 | chr8 | GO:0070302 | Not Cancer Driver | No | 40 | 0.127 | 39 | 7 | 0.179 | 0 |
| SFRP2 | SFRP2 | Q96HF1 | Secreted frizzled-related protein 2 | chr4 | GO:0070302 | Not Cancer Driver | No | 47 | 0.159 | 1 | 0 | 0.0 | 0 |
| SH3RF2 | SH3RF2 | Q8TEC5 | E3 ubiquitin-protein ligase SH3RF2 | chr5 | GO:0070302 | Not Cancer Driver | No | 151 | 0.207 | 455 | 101 | 0.222 | 0 |
| SIRPA_ENST00000400068 | SIRPA | P78324 | Tyrosine-protein phosphatase non-receptor type substrate 1 | chr20 | GO:0070302 | Census, Compendium | Yes | 96 | 0.19 | 281 | 51 | 0.181 | 0 |
| SPHK1_ENST00000545180 | SPHK1 | Q9NYA1 | Sphingosine kinase 1 | chr17 | GO:0070302 | Not Cancer Driver | No | 47 | 0.122 | 25 | 2 | 0.08 | 0 |
| SPI1_ENST00000378538 | SPI1 | P17947 | Transcription factor PU.1 | chr11 | GO:0070302 | Not Cancer Driver | No | 46 | 0.17 | 187 | 34 | 0.182 | 0 |
| STK39 | STK39 | Q9UEW8 | STE20/SPS1-related proline-alanine-rich protein kinase | chr2 | GO:0070302 | Not Cancer Driver | No | 64 | 0.117 | 182 | 19 | 0.104 | 0 |
| TAOK3 | TAOK3 | Q9H2K8 | Serine/threonine-protein kinase TAO3 | chr12 | GO:0070302 | Not Cancer Driver | No | 123 | 0.137 | 494 | 64 | 0.13 | 0 |
| TREM2 | TREM2 | Q9NZC2 | Triggering receptor expressed on myeloid cells 2 | chr6 | GO:0070302 | Not Cancer Driver | No | 43 | 0.187 | 27 | 2 | 0.074 | 1 |
| ULK4 | ULK4 | Q96C45 | Serine/threonine-protein kinase ULK4 | chr3 | GO:0070302 | Not Cancer Driver | No | 162 | 0.127 | 180 | 33 | 0.183 | 0 |
| VEGFA_ENST00000523873 | VEGFA | P15692 | Vascular endothelial growth factor A | chr6 | GO:0070302 | Not Cancer Driver | No | 27 | 0.116 | 41 | 7 | 0.171 | 0 |
| XDH | XDH | P47989 | Xanthine dehydrogenase/oxidase | chr2 | GO:0070302 | Not Cancer Driver | No | 279 | 0.209 | 134 | 24 | 0.179 | 1 |
| ZC3H12A | ZC3H12A | Q5D1E8 | Endoribonuclease ZC3H12A | chr1 | GO:0070302 | Not Cancer Driver | No | 90 | 0.15 | 396 | 44 | 0.111 | 0 |
| ZMPSTE24 | ZMPSTE24 | O75844 | CAAX prenyl protease 1 homolog | chr1 | GO:0070302 | Not Cancer Driver | No | 67 | 0.141 | 23 | 0 | 0.0 | 3 |
| ZMYND11 | ZMYND11 | Q15326 | Zinc finger MYND domain-containing protein 11 | chr10 | GO:0070302 | Not Cancer Driver | No | 71 | 0.118 | 184 | 26 | 0.141 | 0 |
| ZNF675 | ZNF675 | Q8TD23 | Zinc finger protein 675 | chr19 | GO:0070302 | Not Cancer Driver | No | 114 | 0.201 | 91 | 19 | 0.209 | 0 |