Total number of protein in "GO:0061630" GO term: 307
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AMFR | AMFR | Q9UKV5 | E3 ubiquitin-protein ligase AMFR | chr16 | GO:0061630 | Not Cancer Driver | No | 73 | 0.114 | 229 | 30 | 0.131 | 0 |
| ANAPC11_ENST00000579978 | ANAPC11 | Q9NYG5 | Anaphase-promoting complex subunit 11 | chr17 | GO:0061630 | Not Cancer Driver | No | 7 | 0.083 | 0 | 0 | 0.0 | 0 |
| ANKIB1 | ANKIB1 | Q9P2G1 | Ankyrin repeat and IBR domain-containing protein 1 | chr7 | GO:0061630 | Not Cancer Driver | No | 141 | 0.129 | 577 | 78 | 0.135 | 0 |
| AREL1 | AREL1 | O15033 | Apoptosis-resistant E3 ubiquitin protein ligase 1 | chr14 | GO:0061630 | Not Cancer Driver | No | 104 | 0.126 | 92 | 10 | 0.109 | 0 |
| ARIH1 | ARIH1 | Q9Y4X5 | E3 ubiquitin-protein ligase ARIH1 | chr15 | GO:0061630 | Not Cancer Driver | No | 46 | 0.083 | 119 | 7 | 0.059 | 0 |
| ARIH2 | ARIH2 | O95376 | E3 ubiquitin-protein ligase ARIH2 | chr3 | GO:0061630 | Not Cancer Driver | No | 64 | 0.13 | 85 | 11 | 0.129 | 0 |
| ASB1 | ASB1 | Q9Y576 | Ankyrin repeat and SOCS box protein 1 | chr2 | GO:0061630 | Not Cancer Driver | No | 49 | 0.146 | 37 | 2 | 0.054 | 0 |
| ASB12 | ASB12 | Q8WXK4 | Ankyrin repeat and SOCS box protein 12 | chrX | GO:0061630 | Not Cancer Driver | No | 77 | 0.249 | 21 | 3 | 0.143 | 0 |
| ASB2 | ASB2 | Q96Q27 | Ankyrin repeat and SOCS box protein 2 | chr14 | GO:0061630 | Not Cancer Driver | No | 90 | 0.142 | 167 | 19 | 0.114 | 0 |
| ASB4 | ASB4 | Q9Y574 | Ankyrin repeat and SOCS box protein 4 | chr7 | GO:0061630 | Not Cancer Driver | No | 82 | 0.192 | 19 | 1 | 0.053 | 0 |
| BFAR | BFAR | Q9NZS9 | Bifunctional apoptosis regulator | chr16 | GO:0061630 | Not Cancer Driver | No | 56 | 0.124 | 30 | 1 | 0.033 | 0 |
| BIRC2 | BIRC2 | Q13490 | Baculoviral IAP repeat-containing protein 2 | chr11 | GO:0061630 | Not Cancer Driver | No | 69 | 0.112 | 83 | 9 | 0.108 | 0 |
| BIRC3_ENST00000532808 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | GO:0061630 | Census, Compendium | Yes | 77 | 0.127 | 98 | 16 | 0.163 | 0 |
| BIRC7 | BIRC7 | Q96CA5 | Baculoviral IAP repeat-containing protein 7 | chr20 | GO:0061630 | Not Cancer Driver | No | 52 | 0.174 | 136 | 22 | 0.162 | 0 |
| BIRC8 | BIRC8 | Q96P09 | Baculoviral IAP repeat-containing protein 8 | chr19 | GO:0061630 | Not Cancer Driver | No | 79 | 0.335 | 39 | 10 | 0.256 | 0 |
| BRAP | BRAP | Q7Z569 | BRCA1-associated protein | chr12 | GO:0061630 | Not Cancer Driver | No | 70 | 0.118 | 192 | 24 | 0.125 | 0 |
| BSPRY | BSPRY | Q5W0U4 | B box and SPRY domain-containing protein | chr9 | GO:0061630 | Not Cancer Driver | No | 41 | 0.102 | 89 | 5 | 0.056 | 0 |
| BTRC | BTRC | Q9Y297 | F-box/WD repeat-containing protein 1A | chr10 | GO:0061630 | Not Cancer Driver | No | 80 | 0.132 | 45 | 4 | 0.089 | 0 |
| C10orf90 | C10orf90 | Q96M02 | (E2-independent) E3 ubiquitin-conjugating enzyme FATS | chr10 | GO:0061630 | Not Cancer Driver | No | 143 | 0.205 | 496 | 102 | 0.206 | 0 |
| C18orf25 | C18orf25 | Q96B23 | Uncharacterized protein C18orf25 | chr18 | GO:0061630 | Not Cancer Driver | No | 30 | 0.074 | 393 | 27 | 0.069 | 0 |
| CBL | CBL | P22681 | E3 ubiquitin-protein ligase CBL | chr11 | GO:0061630 | Census, Compendium | Yes | 115 | 0.127 | 512 | 56 | 0.109 | 4 |
| CBLB | CBLB | Q13191 | E3 ubiquitin-protein ligase CBL-B | chr3 | GO:0061630 | Census | Yes | 160 | 0.163 | 562 | 104 | 0.185 | 0 |
| CBLC_ENST00000647358 | CBLC | Q9ULV8 | E3 ubiquitin-protein ligase CBL-C | chr19 | GO:0061630 | Census | Yes | 60 | 0.127 | 128 | 21 | 0.164 | 0 |
| CBLL1 | CBLL1 | Q75N03 | E3 ubiquitin-protein ligase Hakai | chr7 | GO:0061630 | Not Cancer Driver | No | 72 | 0.147 | 373 | 49 | 0.131 | 0 |
| CBLL2 | CBLL2 | Q8N7E2 | E3 ubiquitin-protein ligase CBLL2 | chrX | GO:0061630 | Not Cancer Driver | No | 110 | 0.259 | 283 | 71 | 0.251 | 0 |
| CCNB1IP1 | CCNB1IP1 | Q9NPC3 | E3 ubiquitin-protein ligase CCNB1IP1 | chr14 | GO:0061630 | Census | Yes | 43 | 0.155 | 68 | 13 | 0.191 | 0 |
| CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | GO:0061630 | Not Cancer Driver | No | 39 | 0.204 | 23 | 2 | 0.087 | 1 |
| CHFR | CHFR | Q96EP1 | E3 ubiquitin-protein ligase CHFR | chr12 | GO:0061630 | Not Cancer Driver | No | 85 | 0.128 | 341 | 54 | 0.158 | 0 |
| COP1 | COP1 | Q8NHY2 | E3 ubiquitin-protein ligase COP1 | chr1 | GO:0061630 | Not Cancer Driver | No | 106 | 0.145 | 147 | 11 | 0.075 | 0 |
| CUL3 | CUL3 | Q13618 | Cullin-3 | chr2 | GO:0061630 | Census, Compendium | Yes | 123 | 0.16 | 167 | 23 | 0.138 | 3 |
| DCST1 | DCST1 | Q5T197 | E3 ubiquitin-protein ligase DCST1 | chr1 | GO:0061630 | Not Cancer Driver | No | 108 | 0.153 | 51 | 9 | 0.176 | 0 |
| DTX1 | DTX1 | Q86Y01 | E3 ubiquitin-protein ligase DTX1 | chr12 | GO:0061630 | Compendium | Yes | 107 | 0.173 | 304 | 43 | 0.141 | 0 |
| DTX2 | DTX2 | Q86UW9 | Probable E3 ubiquitin-protein ligase DTX2 | chr7 | GO:0061630 | Not Cancer Driver | No | 84 | 0.135 | 292 | 42 | 0.144 | 0 |
| DTX3L | DTX3L | Q8TDB6 | E3 ubiquitin-protein ligase DTX3L | chr3 | GO:0061630 | Not Cancer Driver | No | 86 | 0.116 | 260 | 24 | 0.092 | 0 |
| DTX3_ENST00000337737 | DTX3 | Q8N9I9 | Probable E3 ubiquitin-protein ligase DTX3 | chr12 | GO:0061630 | Not Cancer Driver | No | 58 | 0.167 | 182 | 31 | 0.17 | 0 |
| DTX4 | DTX4 | Q9Y2E6 | E3 ubiquitin-protein ligase DTX4 | chr11 | GO:0061630 | Not Cancer Driver | No | 84 | 0.136 | 323 | 57 | 0.176 | 0 |
| DZIP3_ENST00000463306 | DZIP3 | Q86Y13 | E3 ubiquitin-protein ligase DZIP3 | chr3 | GO:0061630 | Not Cancer Driver | No | 177 | 0.147 | 370 | 68 | 0.184 | 0 |
| FANCL_ENST00000233741 | FANCL | Q9NW38 | E3 ubiquitin-protein ligase FANCL | chr2 | GO:0061630 | Not Cancer Driver | No | 47 | 0.125 | 11 | 0 | 0.0 | 0 |
| FBXL22 | FBXL22 | Q6P050 | F-box and leucine-rich protein 22 | chr15 | GO:0061630 | Not Cancer Driver | No | 15 | 0.061 | 125 | 3 | 0.024 | 0 |
| FBXO17 | FBXO17 | Q96EF6 | F-box only protein 17 | chr19 | GO:0061630 | Not Cancer Driver | No | 30 | 0.108 | 3 | 1 | 0.333 | 0 |
| FBXO2 | FBXO2 | Q9UK22 | F-box only protein 2 | chr1 | GO:0061630 | Not Cancer Driver | No | 21 | 0.071 | 75 | 1 | 0.013 | 0 |
| FBXO27 | FBXO27 | Q8NI29 | F-box only protein 27 | chr19 | GO:0061630 | Not Cancer Driver | No | 37 | 0.131 | 33 | 3 | 0.091 | 0 |
| FBXO30 | FBXO30 | Q8TB52 | F-box only protein 30 | chr6 | GO:0061630 | Not Cancer Driver | No | 87 | 0.117 | 170 | 22 | 0.129 | 0 |
| FBXO4 | FBXO4 | Q9UKT5 | F-box only protein 4 | chr5 | GO:0061630 | Not Cancer Driver | No | 55 | 0.142 | 68 | 7 | 0.103 | 0 |
| FBXO40 | FBXO40 | Q9UH90 | F-box only protein 40 | chr3 | GO:0061630 | Not Cancer Driver | No | 139 | 0.196 | 197 | 38 | 0.193 | 0 |
| FBXO44_ENST00000251547 | FBXO44 | Q9H4M3 | F-box only protein 44 | chr1 | GO:0061630 | Not Cancer Driver | No | 30 | 0.118 | 27 | 3 | 0.111 | 0 |
| FBXO6 | FBXO6 | Q9NRD1 | F-box only protein 6 | chr1 | GO:0061630 | Not Cancer Driver | No | 31 | 0.106 | 27 | 3 | 0.111 | 0 |
| GID4 | GID4 | Q8IVV7 | Glucose-induced degradation protein 4 homolog | chr17 | GO:0061630 | Not Cancer Driver | No | 24 | 0.08 | 143 | 4 | 0.028 | 0 |
| HACE1 | HACE1 | Q8IYU2 | E3 ubiquitin-protein ligase HACE1 | chr6 | GO:0061630 | Not Cancer Driver | No | 126 | 0.139 | 103 | 12 | 0.117 | 0 |
| HECTD1 | HECTD1 | Q9ULT8 | E3 ubiquitin-protein ligase HECTD1 | chr14 | GO:0061630 | Not Cancer Driver | No | 274 | 0.105 | 991 | 108 | 0.109 | 0 |
| HECW1 | HECW1 | Q76N89 | E3 ubiquitin-protein ligase HECW1 | chr7 | GO:0061630 | Not Cancer Driver | No | 420 | 0.262 | 748 | 191 | 0.255 | 0 |
| HECW2_ENST00000644256 | HECW2 | Q9P2P5 | E3 ubiquitin-protein ligase HECW2 | chr2 | GO:0061630 | Not Cancer Driver | No | 348 | 0.221 | 845 | 195 | 0.231 | 4 |
| HERC2 | HERC2 | O95714 | E3 ubiquitin-protein ligase HERC2 | chr15 | GO:0061630 | Compendium | Yes | 718 | 0.149 | 971 | 150 | 0.154 | 1 |
| HERC3 | HERC3 | Q15034 | Probable E3 ubiquitin-protein ligase HERC3 | chr4 | GO:0061630 | Not Cancer Driver | No | 112 | 0.107 | 56 | 7 | 0.125 | 0 |
| HERC4 | HERC4 | Q5GLZ8 | Probable E3 ubiquitin-protein ligase HERC4 | chr10 | GO:0061630 | Not Cancer Driver | No | 111 | 0.105 | 40 | 2 | 0.05 | 0 |
| HERC5 | HERC5 | Q9UII4 | E3 ISG15--protein ligase HERC5 | chr4 | GO:0061630 | Not Cancer Driver | No | 124 | 0.121 | 118 | 12 | 0.102 | 0 |
| HERC6 | HERC6 | Q8IVU3 | Probable E3 ubiquitin-protein ligase HERC6 | chr4 | GO:0061630 | Not Cancer Driver | No | 146 | 0.143 | 132 | 16 | 0.121 | 0 |
| HLTF_ENST00000494055 | HLTF | Q14527 | Helicase-like transcription factor | chr3 | GO:0061630 | Not Cancer Driver | No | 121 | 0.12 | 353 | 40 | 0.113 | 0 |
| HUWE1_ENST00000262854 | HUWE1 | Q7Z6Z7 | E3 ubiquitin-protein ligase HUWE1 | chrX | GO:0061630 | Not Cancer Driver | No | 669 | 0.153 | 2091 | 329 | 0.157 | 21 |
| IRF2BP1 | IRF2BP1 | Q8IU81 | Interferon regulatory factor 2-binding protein 1 | chr19 | GO:0061630 | Not Cancer Driver | No | 57 | 0.098 | 354 | 33 | 0.093 | 0 |
| IRF2BPL | IRF2BPL | Q9H1B7 | Probable E3 ubiquitin-protein ligase IRF2BPL | chr14 | GO:0061630 | Not Cancer Driver | No | 61 | 0.077 | 526 | 31 | 0.059 | 1 |
| ITCH | ITCH | Q96J02 | E3 ubiquitin-protein ligase Itchy homolog | chr20 | GO:0061630 | Not Cancer Driver | No | 95 | 0.105 | 335 | 42 | 0.125 | 0 |
| KCMF1 | KCMF1 | Q9P0J7 | E3 ubiquitin-protein ligase KCMF1 | chr2 | GO:0061630 | Not Cancer Driver | No | 48 | 0.126 | 270 | 36 | 0.133 | 0 |
| LONRF1 | LONRF1 | Q17RB8 | LON peptidase N-terminal domain and RING finger protein 1 | chr8 | GO:0061630 | Not Cancer Driver | No | 64 | 0.083 | 129 | 9 | 0.07 | 0 |
| LONRF2 | LONRF2 | Q1L5Z9 | LON peptidase N-terminal domain and RING finger protein 2 | chr2 | GO:0061630 | Not Cancer Driver | No | 103 | 0.137 | 242 | 25 | 0.103 | 0 |
| LONRF3 | LONRF3 | Q496Y0 | LON peptidase N-terminal domain and RING finger protein 3 | chrX | GO:0061630 | Not Cancer Driver | No | 105 | 0.138 | 262 | 36 | 0.137 | 0 |
| LRSAM1_ENST00000373322 | LRSAM1 | Q6UWE0 | E3 ubiquitin-protein ligase LRSAM1 | chr9 | GO:0061630 | Not Cancer Driver | No | 86 | 0.119 | 240 | 30 | 0.125 | 1 |
| LTN1_ENST00000361371 | LTN1 | O94822 | E3 ubiquitin-protein ligase listerin | chr21 | GO:0061630 | Not Cancer Driver | No | 192 | 0.109 | 124 | 23 | 0.185 | 0 |
| MAEA | MAEA | Q7L5Y9 | E3 ubiquitin-protein transferase MAEA | chr4 | GO:0061630 | Not Cancer Driver | No | 58 | 0.146 | 64 | 5 | 0.078 | 0 |
| MARCH1 | MARCHF1 | Q8TCQ1 | E3 ubiquitin-protein ligase MARCHF1 | chr4 | GO:0061630 | Not Cancer Driver | No | 65 | 0.225 | 74 | 16 | 0.216 | 0 |
| MARCH2 | MARCHF2 | Q9P0N8 | E3 ubiquitin-protein ligase MARCHF2 | chr19 | GO:0061630 | Not Cancer Driver | No | 33 | 0.134 | 23 | 5 | 0.217 | 0 |
| MARCH5 | MARCHF5 | Q9NX47 | E3 ubiquitin-protein ligase MARCHF5 | chr10 | GO:0061630 | Not Cancer Driver | No | 27 | 0.097 | 0 | 0 | 0.0 | 0 |
| MARCH6 | MARCHF6 | O60337 | E3 ubiquitin-protein ligase MARCHF6 | chr5 | GO:0061630 | Not Cancer Driver | No | 114 | 0.125 | 114 | 13 | 0.114 | 0 |
| MARCH8_ENST00000319836 | MARCHF8 | Q5T0T0 | E3 ubiquitin-protein ligase MARCHF8 | chr10 | GO:0061630 | Not Cancer Driver | No | 31 | 0.107 | 71 | 8 | 0.113 | 0 |
| MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | GO:0061630 | Census, Compendium | Yes | 56 | 0.114 | 297 | 37 | 0.125 | 0 |
| MED10 | MED10 | Q9BTT4 | Mediator of RNA polymerase II transcription subunit 10 | chr5 | GO:0061630 | Not Cancer Driver | No | 14 | 0.104 | 13 | 3 | 0.231 | 0 |
| MED11 | MED11 | Q9P086 | Mediator of RNA polymerase II transcription subunit 11 | chr17 | GO:0061630 | Not Cancer Driver | No | 12 | 0.103 | 24 | 4 | 0.167 | 0 |
| MED12 | MED12 | Q93074 | Mediator of RNA polymerase II transcription subunit 12 | chrX | GO:0061630 | Census, Compendium | Yes | 409 | 0.188 | 974 | 175 | 0.18 | 5 |
| MED24_ENST00000394128 | MED24 | O75448 | Mediator of RNA polymerase II transcription subunit 24 | chr17 | GO:0061630 | Not Cancer Driver | No | 101 | 0.102 | 76 | 0 | 0.0 | 0 |
| MED27 | MED27 | Q6P2C8 | Mediator of RNA polymerase II transcription subunit 27 | chr9 | GO:0061630 | Not Cancer Driver | No | 34 | 0.109 | 61 | 5 | 0.082 | 0 |
| MED30 | MED30 | Q96HR3 | Mediator of RNA polymerase II transcription subunit 30 | chr8 | GO:0061630 | Not Cancer Driver | No | 20 | 0.112 | 93 | 8 | 0.086 | 0 |
| MED31 | MED31 | Q9Y3C7 | Mediator of RNA polymerase II transcription subunit 31 | chr17 | GO:0061630 | Not Cancer Driver | No | 16 | 0.122 | 15 | 1 | 0.067 | 0 |
| MED7 | MED7 | O43513 | Mediator of RNA polymerase II transcription subunit 7 | chr5 | GO:0061630 | Not Cancer Driver | No | 32 | 0.137 | 132 | 19 | 0.144 | 0 |
| MEFV | MEFV | O15553 | Pyrin | chr16 | GO:0061630 | Not Cancer Driver | No | 196 | 0.251 | 397 | 119 | 0.3 | 47 |
| MEX3C | MEX3C | Q5U5Q3 | RNA-binding E3 ubiquitin-protein ligase MEX3C | chr18 | GO:0061630 | Not Cancer Driver | No | 54 | 0.082 | 475 | 32 | 0.067 | 0 |
| MGRN1_ENST00000399577 | MGRN1 | O60291 | E3 ubiquitin-protein ligase MGRN1 | chr16 | GO:0061630 | Not Cancer Driver | No | 76 | 0.138 | 228 | 37 | 0.162 | 0 |
| MIB2_ENST00000504599 | MIB2 | Q96AX9 | E3 ubiquitin-protein ligase MIB2 | chr1 | GO:0061630 | Not Cancer Driver | No | 88 | 0.092 | 307 | 31 | 0.101 | 0 |
| MKRN1 | MKRN1 | Q9UHC7 | E3 ubiquitin-protein ligase makorin-1 | chr7 | GO:0061630 | Not Cancer Driver | No | 42 | 0.087 | 155 | 16 | 0.103 | 0 |
| MKRN2 | MKRN2 | Q9H000 | E3 ubiquitin-protein ligase makorin-2 | chr3 | GO:0061630 | Not Cancer Driver | No | 45 | 0.108 | 145 | 16 | 0.11 | 0 |
| MKRN3 | MKRN3 | Q13064 | Probable E3 ubiquitin-protein ligase makorin-3 | chr15 | GO:0061630 | Not Cancer Driver | No | 197 | 0.389 | 201 | 99 | 0.493 | 4 |
| MSL2 | MSL2 | Q9HCI7 | E3 ubiquitin-protein ligase MSL2 | chr3 | GO:0061630 | Not Cancer Driver | No | 76 | 0.132 | 186 | 34 | 0.183 | 0 |
| MUL1 | MUL1 | Q969V5 | Mitochondrial ubiquitin ligase activator of NFKB 1 | chr1 | GO:0061630 | Not Cancer Driver | No | 48 | 0.136 | 16 | 2 | 0.125 | 0 |
| MYCBP2_ENST00000357337 | MYCBP2 | O75592 | E3 ubiquitin-protein ligase MYCBP2 | chr13 | GO:0061630 | Not Cancer Driver | No | 608 | 0.13 | 1398 | 189 | 0.135 | 0 |
| MYLIP | MYLIP | Q8WY64 | E3 ubiquitin-protein ligase MYLIP | chr6 | GO:0061630 | Not Cancer Driver | No | 56 | 0.126 | 11 | 2 | 0.182 | 0 |
| NCCRP1 | NCCRP1 | Q6ZVX7 | F-box only protein 50 | chr19 | GO:0061630 | Not Cancer Driver | No | 38 | 0.138 | 139 | 22 | 0.158 | 0 |
| NEDD4 | NEDD4 | P46934 | E3 ubiquitin-protein ligase NEDD4 | chr15 | GO:0061630 | Not Cancer Driver | No | 150 | 0.114 | 711 | 79 | 0.111 | 0 |
| NEDD4L | NEDD4L | Q96PU5 | E3 ubiquitin-protein ligase NEDD4-like | chr18 | GO:0061630 | Not Cancer Driver | No | 126 | 0.129 | 463 | 60 | 0.13 | 4 |
| NEURL1 | NEURL1 | O76050 | E3 ubiquitin-protein ligase NEURL1 | chr10 | GO:0061630 | Not Cancer Driver | No | 62 | 0.108 | 153 | 11 | 0.072 | 0 |
| NEURL1B | NEURL1B | A8MQ27 | E3 ubiquitin-protein ligase NEURL1B | chr5 | GO:0061630 | Not Cancer Driver | No | 8 | 0.014 | 250 | 3 | 0.012 | 0 |
| NEURL2 | NEURL2 | Q9BR09 | Neuralized-like protein 2 | chr20 | GO:0061630 | Not Cancer Driver | No | 27 | 0.095 | 71 | 3 | 0.042 | 0 |
| NEURL3 | NEURL3 | Q96EH8 | E3 ubiquitin-protein ligase NEURL3 | chr2 | GO:0061630 | Not Cancer Driver | No | 24 | 0.092 | 23 | 3 | 0.13 | 0 |
| NEURL4 | NEURL4 | Q96JN8 | Neuralized-like protein 4 | chr17 | GO:0061630 | Not Cancer Driver | No | 217 | 0.139 | 751 | 119 | 0.158 | 0 |
| NFX1 | NFX1 | Q12986 | Transcriptional repressor NF-X1 | chr9 | GO:0061630 | Not Cancer Driver | No | 121 | 0.108 | 491 | 46 | 0.094 | 0 |
| NHLRC1 | NHLRC1 | Q6VVB1 | E3 ubiquitin-protein ligase NHLRC1 | chr6 | GO:0061630 | Not Cancer Driver | No | 66 | 0.167 | 18 | 3 | 0.167 | 22 |
| NHLRC3 | NHLRC3 | Q5JS37 | NHL repeat-containing protein 3 | chr13 | GO:0061630 | Not Cancer Driver | No | 40 | 0.115 | 7 | 0 | 0.0 | 0 |
| NHLRC4_ENST00000540585 | NHLRC4 | P0CG21 | NHL-repeat-containing protein 4 | chr16 | GO:0061630 | Not Cancer Driver | No | 14 | 0.114 | 0 | 0 | 0.0 | 0 |
| NOSIP | NOSIP | Q9Y314 | Nitric oxide synthase-interacting protein | chr19 | GO:0061630 | Not Cancer Driver | No | 37 | 0.123 | 159 | 21 | 0.132 | 0 |
| NSMCE1 | NSMCE1 | Q8WV22 | Non-structural maintenance of chromosomes element 1 homolog | chr16 | GO:0061630 | Not Cancer Driver | No | 40 | 0.15 | 31 | 8 | 0.258 | 0 |
| PDZRN3 | PDZRN3 | Q9UPQ7 | E3 ubiquitin-protein ligase PDZRN3 | chr3 | GO:0061630 | Not Cancer Driver | No | 234 | 0.22 | 699 | 195 | 0.279 | 0 |
| PELI1 | PELI1 | Q96FA3 | E3 ubiquitin-protein ligase pellino homolog 1 | chr2 | GO:0061630 | Not Cancer Driver | No | 47 | 0.112 | 167 | 17 | 0.102 | 0 |
| PELI2 | PELI2 | Q9HAT8 | E3 ubiquitin-protein ligase pellino homolog 2 | chr14 | GO:0061630 | Not Cancer Driver | No | 80 | 0.19 | 162 | 38 | 0.235 | 0 |
| PELI3 | PELI3 | Q8N2H9 | E3 ubiquitin-protein ligase pellino homolog 3 | chr11 | GO:0061630 | Not Cancer Driver | No | 48 | 0.102 | 216 | 25 | 0.116 | 0 |
| PJA1 | PJA1 | Q8NG27 | E3 ubiquitin-protein ligase Praja-1 | chrX | GO:0061630 | Not Cancer Driver | No | 112 | 0.174 | 525 | 94 | 0.179 | 0 |
| PPIL2_ENST00000335025 | PPIL2 | Q13356 | RING-type E3 ubiquitin-protein ligase PPIL2 | chr22 | GO:0061630 | Not Cancer Driver | No | 64 | 0.123 | 212 | 19 | 0.09 | 0 |
| PPP1R11 | PPP1R11 | O60927 | E3 ubiquitin-protein ligase PPP1R11 | chr6 | GO:0061630 | Not Cancer Driver | No | 17 | 0.135 | 126 | 17 | 0.135 | 0 |
| PRKN | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | GO:0061630 | Not Cancer Driver | No | 110 | 0.237 | 78 | 15 | 0.192 | 31 |
| PRPF19 | PRPF19 | Q9UMS4 | Pre-mRNA-processing factor 19 | chr11 | GO:0061630 | Not Cancer Driver | No | 71 | 0.141 | 109 | 16 | 0.147 | 0 |
| RABGEF1_ENST00000284957 | RABGEF1 | Q9UJ41 | Rab5 GDP/GTP exchange factor | chr7 | GO:0061630 | Not Cancer Driver | No | 73 | 0.149 | 175 | 35 | 0.2 | 0 |
| RAD18 | RAD18 | Q9NS91 | E3 ubiquitin-protein ligase RAD18 | chr3 | GO:0061630 | Not Cancer Driver | No | 59 | 0.119 | 328 | 43 | 0.131 | 0 |
| RAG1 | RAG1 | P15918 | V(D)J recombination-activating protein 1 | chr11 | GO:0061630 | Not Cancer Driver | No | 204 | 0.196 | 208 | 43 | 0.207 | 36 |
| RAG2 | RAG2 | P55895 | V(D)J recombination-activating protein 2 | chr11 | GO:0061630 | Not Cancer Driver | No | 118 | 0.224 | 85 | 23 | 0.271 | 6 |
| RBBP6 | RBBP6 | Q7Z6E9 | E3 ubiquitin-protein ligase RBBP6 | chr16 | GO:0061630 | Not Cancer Driver | No | 229 | 0.128 | 1626 | 212 | 0.13 | 0 |
| RBX1 | RBX1 | P62877 | E3 ubiquitin-protein ligase RBX1 | chr22 | GO:0061630 | Not Cancer Driver | No | 10 | 0.093 | 18 | 1 | 0.056 | 0 |
| RC3H1_ENST00000258349 | RC3H1 | Q5TC82 | Roquin-1 | chr1 | GO:0061630 | Not Cancer Driver | No | 158 | 0.139 | 796 | 115 | 0.144 | 0 |
| RC3H2_ENST00000357244 | RC3H2 | Q9HBD1 | Roquin-2 | chr9 | GO:0061630 | Not Cancer Driver | No | 128 | 0.107 | 703 | 81 | 0.115 | 0 |
| RCHY1 | RCHY1 | Q96PM5 | RING finger and CHY zinc finger domain-containing protein 1 | chr4 | GO:0061630 | Not Cancer Driver | No | 33 | 0.126 | 23 | 0 | 0.0 | 0 |
| RFFL_ENST00000394597 | RFFL | Q8WZ73 | E3 ubiquitin-protein ligase rififylin | chr17 | GO:0061630 | Not Cancer Driver | No | 50 | 0.138 | 150 | 21 | 0.14 | 0 |
| RFWD3 | RFWD3 | Q6PCD5 | E3 ubiquitin-protein ligase RFWD3 | chr16 | GO:0061630 | Census | Yes | 68 | 0.088 | 318 | 30 | 0.094 | 1 |
| RING1 | RING1 | Q06587 | E3 ubiquitin-protein ligase RING1 | chr6 | GO:0061630 | Not Cancer Driver | No | 60 | 0.148 | 302 | 44 | 0.146 | 0 |
| RLIM_ENST00000349225 | RLIM | Q9NVW2 | E3 ubiquitin-protein ligase RLIM | chrX | GO:0061630 | Not Cancer Driver | No | 106 | 0.17 | 545 | 94 | 0.172 | 4 |
| RMND5A | RMND5A | Q9H871 | E3 ubiquitin-protein transferase RMND5A | chr2 | GO:0061630 | Not Cancer Driver | No | 46 | 0.118 | 0 | 0 | 0.0 | 0 |
| RMND5B | RMND5B | Q96G75 | E3 ubiquitin-protein transferase RMND5B | chr5 | GO:0061630 | Not Cancer Driver | No | 34 | 0.087 | 0 | 0 | 0.0 | 0 |
| RNF10_ENST00000325954 | RNF10 | Q8N5U6 | RING finger protein 10 | chr12 | GO:0061630 | Not Cancer Driver | No | 108 | 0.133 | 455 | 63 | 0.138 | 0 |
| RNF11 | RNF11 | Q9Y3C5 | RING finger protein 11 | chr1 | GO:0061630 | Not Cancer Driver | No | 17 | 0.11 | 76 | 7 | 0.092 | 0 |
| RNF111_ENST00000557998 | RNF111 | Q6ZNA4 | E3 ubiquitin-protein ligase Arkadia | chr15 | GO:0061630 | Not Cancer Driver | No | 111 | 0.112 | 855 | 96 | 0.112 | 0 |
| RNF112 | RNF112 | Q9ULX5 | RING finger protein 112 | chr17 | GO:0061630 | Not Cancer Driver | No | 86 | 0.136 | 168 | 26 | 0.155 | 0 |
| RNF113A | RNF113A | O15541 | E3 ubiquitin-protein ligase RNF113A | chrX | GO:0061630 | Not Cancer Driver | No | 61 | 0.178 | 226 | 51 | 0.226 | 0 |
| RNF114 | RNF114 | Q9Y508 | E3 ubiquitin-protein ligase RNF114 | chr20 | GO:0061630 | Not Cancer Driver | No | 19 | 0.083 | 14 | 2 | 0.143 | 0 |
| RNF115 | RNF115 | Q9Y4L5 | E3 ubiquitin-protein ligase RNF115 | chr1 | GO:0061630 | Not Cancer Driver | No | 30 | 0.099 | 136 | 14 | 0.103 | 0 |
| RNF121 | RNF121 | Q9H920 | RING finger protein 121 | chr11 | GO:0061630 | Not Cancer Driver | No | 32 | 0.098 | 3 | 0 | 0.0 | 0 |
| RNF122 | RNF122 | Q9H9V4 | RING finger protein 122 | chr8 | GO:0061630 | Not Cancer Driver | No | 24 | 0.155 | 0 | 0 | 0.0 | 0 |
| RNF125 | RNF125 | Q96EQ8 | E3 ubiquitin-protein ligase RNF125 | chr18 | GO:0061630 | Not Cancer Driver | No | 35 | 0.151 | 26 | 1 | 0.038 | 3 |
| RNF126 | RNF126 | Q9BV68 | E3 ubiquitin-protein ligase RNF126 | chr19 | GO:0061630 | Not Cancer Driver | No | 33 | 0.106 | 182 | 22 | 0.121 | 0 |
| RNF128 | RNF128 | Q8TEB7 | E3 ubiquitin-protein ligase RNF128 | chrX | GO:0061630 | Not Cancer Driver | No | 61 | 0.143 | 123 | 15 | 0.122 | 0 |
| RNF130 | RNF130 | Q86XS8 | E3 ubiquitin-protein ligase RNF130 | chr5 | GO:0061630 | Not Cancer Driver | No | 45 | 0.107 | 43 | 5 | 0.116 | 0 |
| RNF133 | RNF133 | Q8WVZ7 | E3 ubiquitin-protein ligase RNF133 | chr7 | GO:0061630 | Not Cancer Driver | No | 76 | 0.202 | 60 | 5 | 0.083 | 0 |
| RNF135 | RNF135 | Q8IUD6 | E3 ubiquitin-protein ligase RNF135 | chr17 | GO:0061630 | Not Cancer Driver | No | 40 | 0.093 | 139 | 11 | 0.079 | 0 |
| RNF138 | RNF138 | Q8WVD3 | E3 ubiquitin-protein ligase RNF138 | chr18 | GO:0061630 | Not Cancer Driver | No | 44 | 0.18 | 34 | 6 | 0.176 | 0 |
| RNF139 | RNF139 | Q8WU17 | E3 ubiquitin-protein ligase RNF139 | chr8 | GO:0061630 | Not Cancer Driver | No | 76 | 0.114 | 68 | 4 | 0.059 | 0 |
| RNF13_ENST00000392894 | RNF13 | O43567 | E3 ubiquitin-protein ligase RNF13 | chr3 | GO:0061630 | Not Cancer Driver | No | 45 | 0.118 | 107 | 17 | 0.159 | 2 |
| RNF14 | RNF14 | Q9UBS8 | E3 ubiquitin-protein ligase RNF14 | chr5 | GO:0061630 | Not Cancer Driver | No | 52 | 0.11 | 40 | 8 | 0.2 | 0 |
| RNF144A | RNF144A | P50876 | E3 ubiquitin-protein ligase RNF144A | chr2 | GO:0061630 | Not Cancer Driver | No | 63 | 0.216 | 0 | 0 | 0.0 | 0 |
| RNF144B | RNF144B | Q7Z419 | E3 ubiquitin-protein ligase RNF144B | chr6 | GO:0061630 | Not Cancer Driver | No | 32 | 0.106 | 4 | 1 | 0.25 | 0 |
| RNF145_ENST00000519865 | RNF145 | Q96MT1 | RING finger protein 145 | chr5 | GO:0061630 | Not Cancer Driver | No | 94 | 0.142 | 78 | 10 | 0.128 | 0 |
| RNF146 | RNF146 | Q9NTX7 | E3 ubiquitin-protein ligase RNF146 | chr6 | GO:0061630 | Not Cancer Driver | No | 37 | 0.103 | 206 | 24 | 0.117 | 0 |
| RNF148 | RNF148 | Q8N7C7 | RING finger protein 148 | chr7 | GO:0061630 | Not Cancer Driver | No | 75 | 0.246 | 8 | 3 | 0.375 | 0 |
| RNF149 | RNF149 | Q8NC42 | E3 ubiquitin-protein ligase RNF149 | chr2 | GO:0061630 | Not Cancer Driver | No | 41 | 0.102 | 102 | 10 | 0.098 | 0 |
| RNF150 | RNF150 | Q9ULK6 | RING finger protein 150 | chr4 | GO:0061630 | Not Cancer Driver | No | 72 | 0.164 | 144 | 15 | 0.104 | 0 |
| RNF151 | RNF151 | Q2KHN1 | RING finger protein 151 | chr16 | GO:0061630 | Not Cancer Driver | No | 26 | 0.106 | 47 | 5 | 0.106 | 0 |
| RNF152 | RNF152 | Q8N8N0 | E3 ubiquitin-protein ligase RNF152 | chr18 | GO:0061630 | Not Cancer Driver | No | 61 | 0.3 | 34 | 11 | 0.324 | 0 |
| RNF157 | RNF157 | Q96PX1 | E3 ubiquitin ligase RNF157 | chr17 | GO:0061630 | Not Cancer Driver | No | 76 | 0.112 | 375 | 39 | 0.104 | 0 |
| RNF165 | RNF165 | Q6ZSG1 | E3 ubiquitin-protein ligase RNF165 | chr18 | GO:0061630 | Not Cancer Driver | No | 62 | 0.179 | 225 | 40 | 0.178 | 0 |
| RNF166 | RNF166 | Q96A37 | E3 ubiquitin-protein ligase RNF166 | chr16 | GO:0061630 | Not Cancer Driver | No | 18 | 0.076 | 24 | 2 | 0.083 | 0 |
| RNF167_ENST00000571816 | RNF167 | Q9H6Y7 | E3 ubiquitin-protein ligase RNF167 | chr17 | GO:0061630 | Not Cancer Driver | No | 35 | 0.1 | 102 | 18 | 0.176 | 0 |
| RNF170_ENST00000527424 | RNF170 | Q96K19 | E3 ubiquitin-protein ligase RNF170 | chr8 | GO:0061630 | Not Cancer Driver | No | 14 | 0.054 | 0 | 0 | 0.0 | 1 |
| RNF175 | RNF175 | Q8N4F7 | RING finger protein 175 | chr4 | GO:0061630 | Not Cancer Driver | No | 44 | 0.134 | 4 | 0 | 0.0 | 0 |
| RNF180 | RNF180 | Q86T96 | E3 ubiquitin-protein ligase RNF180 | chr5 | GO:0061630 | Not Cancer Driver | No | 80 | 0.135 | 190 | 26 | 0.137 | 0 |
| RNF181 | RNF181 | Q9P0P0 | E3 ubiquitin-protein ligase RNF181 | chr2 | GO:0061630 | Not Cancer Driver | No | 15 | 0.098 | 63 | 8 | 0.127 | 0 |
| RNF183_ENST00000297894 | RNF183 | Q96D59 | E3 ubiquitin-protein ligase RNF183 | chr9 | GO:0061630 | Not Cancer Driver | No | 22 | 0.115 | 29 | 1 | 0.034 | 0 |
| RNF185 | RNF185 | Q96GF1 | E3 ubiquitin-protein ligase RNF185 | chr22 | GO:0061630 | Not Cancer Driver | No | 25 | 0.13 | 82 | 15 | 0.183 | 0 |
| RNF186 | RNF186 | Q9NXI6 | E3 ubiquitin-protein ligase RNF186 | chr1 | GO:0061630 | Not Cancer Driver | No | 27 | 0.119 | 11 | 3 | 0.273 | 0 |
| RNF187_ENST00000639044 | RNF187 | Q5TA31 | E3 ubiquitin-protein ligase RNF187 | chr1 | GO:0061630 | Not Cancer Driver | No | 2 | 0.009 | 104 | 1 | 0.01 | 0 |
| RNF19A | RNF19A | Q9NV58 | E3 ubiquitin-protein ligase RNF19A | chr8 | GO:0061630 | Not Cancer Driver | No | 112 | 0.134 | 387 | 55 | 0.142 | 0 |
| RNF19B | RNF19B | Q6ZMZ0 | E3 ubiquitin-protein ligase RNF19B | chr1 | GO:0061630 | Not Cancer Driver | No | 58 | 0.079 | 344 | 24 | 0.07 | 0 |
| RNF2 | RNF2 | Q99496 | E3 ubiquitin-protein ligase RING2 | chr1 | GO:0061630 | Not Cancer Driver | No | 40 | 0.119 | 203 | 22 | 0.108 | 0 |
| RNF20 | RNF20 | Q5VTR2 | E3 ubiquitin-protein ligase BRE1A | chr9 | GO:0061630 | Not Cancer Driver | No | 126 | 0.129 | 561 | 64 | 0.114 | 0 |
| RNF208 | RNF208 | Q9H0X6 | RING finger protein 208 | chr9 | GO:0061630 | Not Cancer Driver | No | 20 | 0.077 | 113 | 9 | 0.08 | 0 |
| RNF213 | RNF213 | Q63HN8 | E3 ubiquitin-protein ligase RNF213 | chr17 | GO:0061630 | Census, Compendium | Yes | 560 | 0.108 | 623 | 75 | 0.12 | 3 |
| RNF215 | RNF215 | Q9Y6U7 | RING finger protein 215 | chr22 | GO:0061630 | Not Cancer Driver | No | 30 | 0.08 | 62 | 2 | 0.032 | 0 |
| RNF216_ENST00000425013 | RNF216 | Q9NWF9 | E3 ubiquitin-protein ligase RNF216 | chr7 | GO:0061630 | Not Cancer Driver | No | 108 | 0.125 | 415 | 57 | 0.137 | 2 |
| RNF217 | RNF217 | Q8TC41 | E3 ubiquitin-protein ligase RNF217 | chr6 | GO:0061630 | Not Cancer Driver | No | 70 | 0.129 | 203 | 13 | 0.064 | 0 |
| RNF220_ENST00000361799 | RNF220 | Q5VTB9 | E3 ubiquitin-protein ligase RNF220 | chr1 | GO:0061630 | Not Cancer Driver | No | 104 | 0.184 | 401 | 75 | 0.187 | 0 |
| RNF227 | RNF227 | A6NIN4 | RING finger protein 227 | chr17 | GO:0061630 | Not Cancer Driver | No | 1 | 0.005 | 41 | 1 | 0.024 | 0 |
| RNF24_ENST00000358395 | RNF24 | Q9Y225 | RING finger protein 24 | chr20 | GO:0061630 | Not Cancer Driver | No | 18 | 0.122 | 13 | 3 | 0.231 | 0 |
| RNF25 | RNF25 | Q96BH1 | E3 ubiquitin-protein ligase RNF25 | chr2 | GO:0061630 | Not Cancer Driver | No | 56 | 0.122 | 285 | 42 | 0.147 | 0 |
| RNF26 | RNF26 | Q9BY78 | E3 ubiquitin-protein ligase RNF26 | chr11 | GO:0061630 | Not Cancer Driver | No | 44 | 0.102 | 71 | 7 | 0.099 | 0 |
| RNF31 | RNF31 | Q96EP0 | E3 ubiquitin-protein ligase RNF31 | chr14 | GO:0061630 | Not Cancer Driver | No | 142 | 0.132 | 319 | 45 | 0.141 | 0 |
| RNF34_ENST00000361234 | RNF34 | Q969K3 | E3 ubiquitin-protein ligase RNF34 | chr12 | GO:0061630 | Not Cancer Driver | No | 30 | 0.081 | 112 | 7 | 0.062 | 0 |
| RNF38 | RNF38 | Q9H0F5 | E3 ubiquitin-protein ligase RNF38 | chr9 | GO:0061630 | Not Cancer Driver | No | 70 | 0.136 | 348 | 47 | 0.135 | 0 |
| RNF39 | RNF39 | Q9H2S5 | RING finger protein 39 | chr6 | GO:0061630 | Not Cancer Driver | No | 42 | 0.1 | 205 | 23 | 0.112 | 0 |
| RNF40 | RNF40 | O75150 | E3 ubiquitin-protein ligase BRE1B | chr16 | GO:0061630 | Not Cancer Driver | No | 132 | 0.132 | 645 | 80 | 0.124 | 0 |
| RNF41_ENST00000615206 | RNF41 | Q9H4P4 | E3 ubiquitin-protein ligase NRDP1 | chr12 | GO:0061630 | Not Cancer Driver | No | 44 | 0.139 | 33 | 2 | 0.061 | 0 |
| RNF43_ENST00000577716 | RNF43 | Q68DV7 | E3 ubiquitin-protein ligase RNF43 | chr17 | GO:0061630 | Census, Compendium | Yes | 121 | 0.155 | 437 | 54 | 0.124 | 0 |
| RNF5 | RNF5 | Q99942 | E3 ubiquitin-protein ligase RNF5 | chr6 | GO:0061630 | Not Cancer Driver | No | 17 | 0.094 | 69 | 3 | 0.043 | 0 |
| RNF6 | RNF6 | Q9Y252 | E3 ubiquitin-protein ligase RNF6 | chr13 | GO:0061630 | Compendium | Yes | 91 | 0.133 | 601 | 87 | 0.145 | 0 |
| RNF7 | RNF7 | Q9UBF6 | RING-box protein 2 | chr3 | GO:0061630 | Not Cancer Driver | No | 17 | 0.15 | 0 | 0 | 0.0 | 0 |
| RNF8 | RNF8 | O76064 | E3 ubiquitin-protein ligase RNF8 | chr6 | GO:0061630 | Not Cancer Driver | No | 56 | 0.115 | 226 | 29 | 0.128 | 0 |
| RNFT1 | RNFT1 | Q5M7Z0 | E3 ubiquitin-protein ligase RNFT1 | chr17 | GO:0061630 | Not Cancer Driver | No | 37 | 0.085 | 117 | 18 | 0.154 | 0 |
| RNFT2_ENST00000392549 | RNFT2 | Q96EX2 | RING finger and transmembrane domain-containing protein 2 | chr12 | GO:0061630 | Not Cancer Driver | No | 37 | 0.083 | 129 | 10 | 0.078 | 0 |
| SH3RF1 | SH3RF1 | Q7Z6J0 | E3 ubiquitin-protein ligase SH3RF1 | chr4 | GO:0061630 | Not Cancer Driver | No | 109 | 0.123 | 586 | 72 | 0.123 | 0 |
| SH3RF2 | SH3RF2 | Q8TEC5 | E3 ubiquitin-protein ligase SH3RF2 | chr5 | GO:0061630 | Not Cancer Driver | No | 151 | 0.207 | 455 | 101 | 0.222 | 0 |
| SH3RF3 | SH3RF3 | Q8TEJ3 | E3 ubiquitin-protein ligase SH3RF3 | chr2 | GO:0061630 | Not Cancer Driver | No | 98 | 0.111 | 564 | 53 | 0.094 | 0 |
| SHPRH | SHPRH | Q149N8 | E3 ubiquitin-protein ligase SHPRH | chr6 | GO:0061630 | Not Cancer Driver | No | 227 | 0.135 | 359 | 51 | 0.142 | 0 |
| SIAH1_ENST00000394725 | SIAH1 | Q8IUQ4 | E3 ubiquitin-protein ligase SIAH1 | chr16 | GO:0061630 | Not Cancer Driver | No | 35 | 0.124 | 28 | 2 | 0.071 | 5 |
| SIAH2 | SIAH2 | O43255 | E3 ubiquitin-protein ligase SIAH2 | chr3 | GO:0061630 | Not Cancer Driver | No | 48 | 0.148 | 68 | 3 | 0.044 | 0 |
| SIAH3 | SIAH3 | Q8IW03 | Seven in absentia homolog 3 | chr13 | GO:0061630 | Not Cancer Driver | No | 60 | 0.223 | 51 | 9 | 0.176 | 0 |
| SMURF1 | SMURF1 | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 | chr7 | GO:0061630 | Not Cancer Driver | No | 89 | 0.118 | 256 | 31 | 0.121 | 0 |
| SMURF2 | SMURF2 | Q9HAU4 | E3 ubiquitin-protein ligase SMURF2 | chr17 | GO:0061630 | Not Cancer Driver | No | 87 | 0.116 | 242 | 28 | 0.116 | 0 |
| STUB1 | STUB1 | Q9UNE7 | E3 ubiquitin-protein ligase CHIP | chr16 | GO:0061630 | Not Cancer Driver | No | 35 | 0.116 | 112 | 14 | 0.125 | 12 |
| SYVN1 | SYVN1 | Q86TM6 | E3 ubiquitin-protein ligase synoviolin | chr11 | GO:0061630 | Not Cancer Driver | No | 63 | 0.102 | 284 | 32 | 0.113 | 0 |
| TMEM129_ENST00000536901 | TMEM129 | A0AVI4 | E3 ubiquitin-protein ligase TM129 | chr4 | GO:0061630 | Not Cancer Driver | No | 15 | 0.041 | 8 | 1 | 0.125 | 0 |
| TOPORS | TOPORS | Q9NS56 | E3 ubiquitin-protein ligase Topors | chr9 | GO:0061630 | Not Cancer Driver | No | 149 | 0.143 | 795 | 105 | 0.132 | 0 |
| TRAF3IP2_ENST00000392556 | TRAF3IP2 | O43734 | E3 ubiquitin ligase TRAF3IP2 | chr6 | GO:0061630 | Not Cancer Driver | No | 59 | 0.103 | 410 | 39 | 0.095 | 2 |
| TRAF6_ENST00000348124 | TRAF6 | Q9Y4K3 | TNF receptor-associated factor 6 | chr11 | GO:0061630 | Not Cancer Driver | No | 67 | 0.128 | 62 | 7 | 0.113 | 0 |
| TRAIP | TRAIP | Q9BWF2 | E3 ubiquitin-protein ligase TRAIP | chr3 | GO:0061630 | Not Cancer Driver | No | 63 | 0.134 | 240 | 33 | 0.138 | 1 |
| TRIM10 | TRIM10 | Q9UDY6 | Tripartite motif-containing protein 10 | chr6 | GO:0061630 | Not Cancer Driver | No | 95 | 0.198 | 43 | 8 | 0.186 | 0 |
| TRIM11 | TRIM11 | Q96F44 | E3 ubiquitin-protein ligase TRIM11 | chr1 | GO:0061630 | Not Cancer Driver | No | 58 | 0.124 | 132 | 14 | 0.106 | 0 |
| TRIM13_ENST00000378182 | TRIM13 | O60858 | E3 ubiquitin-protein ligase TRIM13 | chr13 | GO:0061630 | Not Cancer Driver | No | 53 | 0.13 | 1 | 0 | 0.0 | 0 |
| TRIM14 | TRIM14 | Q14142 | Tripartite motif-containing protein 14 | chr9 | GO:0061630 | Not Cancer Driver | No | 36 | 0.081 | 93 | 7 | 0.075 | 0 |
| TRIM15 | TRIM15 | Q9C019 | Tripartite motif-containing protein 15 | chr6 | GO:0061630 | Not Cancer Driver | No | 69 | 0.148 | 79 | 11 | 0.139 | 0 |
| TRIM17_ENST00000366698 | TRIM17 | Q9Y577 | E3 ubiquitin-protein ligase TRIM17 | chr1 | GO:0061630 | Not Cancer Driver | No | 64 | 0.134 | 127 | 19 | 0.15 | 0 |
| TRIM21 | TRIM21 | P19474 | E3 ubiquitin-protein ligase TRIM21 | chr11 | GO:0061630 | Not Cancer Driver | No | 85 | 0.179 | 49 | 7 | 0.143 | 0 |
| TRIM22 | TRIM22 | Q8IYM9 | E3 ubiquitin-protein ligase TRIM22 | chr11 | GO:0061630 | Not Cancer Driver | No | 93 | 0.187 | 26 | 1 | 0.038 | 0 |
| TRIM24 | TRIM24 | O15164 | Transcription intermediary factor 1-alpha | chr7 | GO:0061630 | Census, Compendium | Yes | 120 | 0.114 | 537 | 61 | 0.114 | 0 |
| TRIM25 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | GO:0061630 | Not Cancer Driver | No | 59 | 0.094 | 225 | 20 | 0.089 | 0 |
| TRIM26 | TRIM26 | Q12899 | Tripartite motif-containing protein 26 | chr6 | GO:0061630 | Not Cancer Driver | No | 67 | 0.124 | 153 | 16 | 0.105 | 0 |
| TRIM27 | TRIM27 | P14373 | Zinc finger protein RFP | chr6 | GO:0061630 | Census | Yes | 59 | 0.115 | 87 | 11 | 0.126 | 0 |
| TRIM2_ENST00000437508 | TRIM2 | Q9C040 | Tripartite motif-containing protein 2 | chr4 | GO:0061630 | Not Cancer Driver | No | 86 | 0.116 | 238 | 38 | 0.16 | 1 |
| TRIM3 | TRIM3 | O75382 | Tripartite motif-containing protein 3 | chr11 | GO:0061630 | Not Cancer Driver | No | 108 | 0.145 | 253 | 37 | 0.146 | 0 |
| TRIM31 | TRIM31 | Q9BZY9 | E3 ubiquitin-protein ligase TRIM31 | chr6 | GO:0061630 | Not Cancer Driver | No | 55 | 0.129 | 152 | 21 | 0.138 | 0 |
| TRIM32 | TRIM32 | Q13049 | E3 ubiquitin-protein ligase TRIM32 | chr9 | GO:0061630 | Not Cancer Driver | No | 82 | 0.126 | 87 | 10 | 0.115 | 3 |
| TRIM34_ENST00000429814 | TRIM34 | Q9BYJ4 | Tripartite motif-containing protein 34 | chr11 | GO:0061630 | Not Cancer Driver | No | 74 | 0.152 | 32 | 2 | 0.062 | 0 |
| TRIM35 | TRIM35 | Q9UPQ4 | E3 ubiquitin-protein ligase TRIM35 | chr8 | GO:0061630 | Not Cancer Driver | No | 66 | 0.134 | 69 | 9 | 0.13 | 0 |
| TRIM37 | TRIM37 | O94972 | E3 ubiquitin-protein ligase TRIM37 | chr17 | GO:0061630 | Not Cancer Driver | No | 119 | 0.123 | 492 | 60 | 0.122 | 3 |
| TRIM38 | TRIM38 | O00635 | E3 ubiquitin-protein ligase TRIM38 | chr6 | GO:0061630 | Not Cancer Driver | No | 62 | 0.133 | 47 | 8 | 0.17 | 0 |
| TRIM39 | TRIM39 | Q9HCM9 | E3 ubiquitin-protein ligase TRIM39 | chr6 | GO:0061630 | Not Cancer Driver | No | 74 | 0.143 | 62 | 8 | 0.129 | 0 |
| TRIM4 | TRIM4 | Q9C037 | E3 ubiquitin-protein ligase TRIM4 | chr7 | GO:0061630 | Not Cancer Driver | No | 51 | 0.102 | 40 | 5 | 0.125 | 0 |
| TRIM40_ENST00000376724 | TRIM40 | Q6P9F5 | E3 ubiquitin ligase TRIM40 | chr6 | GO:0061630 | Not Cancer Driver | No | 44 | 0.171 | 84 | 12 | 0.143 | 0 |
| TRIM41 | TRIM41 | Q8WV44 | E3 ubiquitin-protein ligase TRIM41 | chr5 | GO:0061630 | Not Cancer Driver | No | 69 | 0.11 | 385 | 38 | 0.099 | 0 |
| TRIM43 | TRIM43 | Q96BQ3 | Tripartite motif-containing protein 43 | chr2 | GO:0061630 | Not Cancer Driver | No | 48 | 0.108 | 28 | 7 | 0.25 | 0 |
| TRIM44 | TRIM44 | Q96DX7 | Tripartite motif-containing protein 44 | chr11 | GO:0061630 | Not Cancer Driver | No | 40 | 0.116 | 272 | 33 | 0.121 | 1 |
| TRIM48 | TRIM48 | Q8IWZ4 | E3 ubiquitin-protein ligase TRIM48 | chr11 | GO:0061630 | Not Cancer Driver | No | 108 | 0.482 | 0 | 0 | 0.0 | 0 |
| TRIM49 | TRIM49 | P0CI25 | Tripartite motif-containing protein 49 | chr11 | GO:0061630 | Not Cancer Driver | No | 120 | 0.265 | 27 | 5 | 0.185 | 0 |
| TRIM49B | TRIM49B | A6NDI0 | Putative tripartite motif-containing protein 49B | chr11 | GO:0061630 | Not Cancer Driver | No | 21 | 0.046 | 31 | 1 | 0.032 | 0 |
| TRIM49C | TRIM49C | P0CI26 | Tripartite motif-containing protein 49C | chr11 | GO:0061630 | Compendium | Yes | 106 | 0.235 | 26 | 3 | 0.115 | 0 |
| TRIM5 | TRIM5 | Q9C035 | Tripartite motif-containing protein 5 | chr11 | GO:0061630 | Not Cancer Driver | No | 71 | 0.144 | 77 | 11 | 0.143 | 0 |
| TRIM50_ENST00000453152 | TRIM50 | Q86XT4 | E3 ubiquitin-protein ligase TRIM50 | chr7 | GO:0061630 | Not Cancer Driver | No | 63 | 0.129 | 80 | 11 | 0.138 | 0 |
| TRIM51 | TRIM51 | Q9BSJ1 | Tripartite motif-containing protein 51 | chr11 | GO:0061630 | Not Cancer Driver | No | 230 | 0.509 | 36 | 28 | 0.778 | 0 |
| TRIM52 | TRIM52 | Q96A61 | E3 ubiquitin-protein ligase TRIM52 | chr5 | GO:0061630 | Not Cancer Driver | No | 23 | 0.077 | 147 | 13 | 0.088 | 0 |
| TRIM54_ENST00000380075 | TRIM54 | Q9BYV2 | Tripartite motif-containing protein 54 | chr2 | GO:0061630 | Not Cancer Driver | No | 63 | 0.176 | 98 | 17 | 0.173 | 0 |
| TRIM55 | TRIM55 | Q9BYV6 | Tripartite motif-containing protein 55 | chr8 | GO:0061630 | Not Cancer Driver | No | 134 | 0.245 | 276 | 78 | 0.283 | 0 |
| TRIM56 | TRIM56 | Q9BRZ2 | E3 ubiquitin-protein ligase TRIM56 | chr7 | GO:0061630 | Not Cancer Driver | No | 110 | 0.146 | 217 | 36 | 0.166 | 0 |
| TRIM58 | TRIM58 | Q8NG06 | E3 ubiquitin-protein ligase TRIM58 | chr1 | GO:0061630 | Not Cancer Driver | No | 194 | 0.399 | 84 | 41 | 0.488 | 0 |
| TRIM59 | TRIM59 | Q8IWR1 | Tripartite motif-containing protein 59 | chr3 | GO:0061630 | Not Cancer Driver | No | 47 | 0.117 | 33 | 6 | 0.182 | 0 |
| TRIM60_ENST00000508504 | TRIM60 | Q495X7 | Tripartite motif-containing protein 60 | chr4 | GO:0061630 | Not Cancer Driver | No | 97 | 0.206 | 3 | 0 | 0.0 | 0 |
| TRIM61 | TRIM61 | Q5EBN2 | Putative tripartite motif-containing protein 61 | chr4 | GO:0061630 | Not Cancer Driver | No | 24 | 0.115 | 24 | 2 | 0.083 | 0 |
| TRIM62 | TRIM62 | Q9BVG3 | E3 ubiquitin-protein ligase TRIM62 | chr1 | GO:0061630 | Not Cancer Driver | No | 58 | 0.122 | 80 | 14 | 0.175 | 0 |
| TRIM63 | TRIM63 | Q969Q1 | E3 ubiquitin-protein ligase TRIM63 | chr1 | GO:0061630 | Not Cancer Driver | No | 47 | 0.133 | 71 | 13 | 0.183 | 0 |
| TRIM64 | TRIM64 | A6NGJ6 | Tripartite motif-containing protein 64 | chr11 | GO:0061630 | Not Cancer Driver | No | 4 | 0.009 | 52 | 0 | 0.0 | 0 |
| TRIM64B | TRIM64B | A6NI03 | Putative tripartite motif-containing protein 64B | chr11 | GO:0061630 | Not Cancer Driver | No | 11 | 0.024 | 51 | 1 | 0.02 | 0 |
| TRIM64C | TRIM64C | A6NLI5 | Tripartite motif-containing protein 64C | chr11 | GO:0061630 | Not Cancer Driver | No | 8 | 0.018 | 33 | 0 | 0.0 | 0 |
| TRIM68 | TRIM68 | Q6AZZ1 | E3 ubiquitin-protein ligase TRIM68 | chr11 | GO:0061630 | Not Cancer Driver | No | 74 | 0.153 | 37 | 7 | 0.189 | 0 |
| TRIM69_ENST00000329464 | TRIM69 | Q86WT6 | E3 ubiquitin-protein ligase TRIM69 | chr15 | GO:0061630 | Not Cancer Driver | No | 78 | 0.156 | 62 | 15 | 0.242 | 0 |
| TRIM6_ENST00000278302 | TRIM6 | Q9C030 | Tripartite motif-containing protein 6 | chr11 | GO:0061630 | Not Cancer Driver | No | 86 | 0.176 | 47 | 15 | 0.319 | 0 |
| TRIM7 | TRIM7 | Q9C029 | E3 ubiquitin-protein ligase TRIM7 | chr5 | GO:0061630 | Not Cancer Driver | No | 60 | 0.117 | 145 | 12 | 0.083 | 0 |
| TRIM71 | TRIM71 | Q2Q1W2 | E3 ubiquitin-protein ligase TRIM71 | chr3 | GO:0061630 | Not Cancer Driver | No | 124 | 0.143 | 163 | 21 | 0.129 | 2 |
| TRIM72 | TRIM72 | Q6ZMU5 | Tripartite motif-containing protein 72 | chr16 | GO:0061630 | Not Cancer Driver | No | 54 | 0.113 | 69 | 14 | 0.203 | 0 |
| TRIM73 | TRIM73 | Q86UV7 | Tripartite motif-containing protein 73 | chr7 | GO:0061630 | Not Cancer Driver | No | 22 | 0.088 | 12 | 2 | 0.167 | 0 |
| TRIM74 | TRIM74 | Q86UV6 | Tripartite motif-containing protein 74 | chr7 | GO:0061630 | Not Cancer Driver | No | 25 | 0.1 | 12 | 1 | 0.083 | 0 |
| TRIM75P | TRIM75 | A6NK02 | Tripartite motif-containing protein 75 | chr4 | GO:0061630 | Not Cancer Driver | No | 21 | 0.045 | 64 | 2 | 0.031 | 0 |
| TRIM77 | TRIM77 | I1YAP6 | Tripartite motif-containing protein 77 | chr11 | GO:0061630 | Not Cancer Driver | No | 40 | 0.089 | 10 | 2 | 0.2 | 0 |
| TRIM9 | TRIM9 | Q9C026 | E3 ubiquitin-protein ligase TRIM9 | chr14 | GO:0061630 | Not Cancer Driver | No | 142 | 0.2 | 112 | 22 | 0.196 | 0 |
| TRIML1 | TRIML1 | Q8N9V2 | Probable E3 ubiquitin-protein ligase TRIML1 | chr4 | GO:0061630 | Not Cancer Driver | No | 152 | 0.325 | 140 | 43 | 0.307 | 0 |
| TRIML2 | TRIML2 | Q8N7C3 | Probable E3 ubiquitin-protein ligase TRIML2 | chr4 | GO:0061630 | Not Cancer Driver | No | 165 | 0.378 | 77 | 28 | 0.364 | 0 |
| TRIP12_ENST00000283943 | TRIP12 | Q14669 | E3 ubiquitin-protein ligase TRIP12 | chr2 | GO:0061630 | Not Cancer Driver | No | 224 | 0.112 | 845 | 117 | 0.138 | 4 |
| UBE2C | UBE2C | O00762 | Ubiquitin-conjugating enzyme E2 C | chr20 | GO:0061630 | Not Cancer Driver | No | 13 | 0.073 | 40 | 0 | 0.0 | 0 |
| UBE2D1 | UBE2D1 | P51668 | Ubiquitin-conjugating enzyme E2 D1 | chr10 | GO:0061630 | Not Cancer Driver | No | 13 | 0.088 | 14 | 0 | 0.0 | 0 |
| UBE2D2 | UBE2D2 | P62837 | Ubiquitin-conjugating enzyme E2 D2 | chr5 | GO:0061630 | Compendium | Yes | 19 | 0.129 | 13 | 1 | 0.077 | 0 |
| UBE2D3_ENST00000394801 | UBE2D3 | P61077 | Ubiquitin-conjugating enzyme E2 D3 | chr4 | GO:0061630 | Not Cancer Driver | No | 21 | 0.143 | 13 | 4 | 0.308 | 0 |
| UBE2K | UBE2K | P61086 | Ubiquitin-conjugating enzyme E2 K | chr4 | GO:0061630 | Not Cancer Driver | No | 24 | 0.12 | 33 | 3 | 0.091 | 0 |
| UBE2O | UBE2O | Q9C0C9 | (E3-independent) E2 ubiquitin-conjugating enzyme | chr17 | GO:0061630 | Not Cancer Driver | No | 129 | 0.1 | 716 | 68 | 0.095 | 0 |
| UBE3A | UBE3A | Q05086 | Ubiquitin-protein ligase E3A | chr15 | GO:0061630 | Not Cancer Driver | No | 141 | 0.161 | 136 | 22 | 0.162 | 0 |
| UBE3B_ENST00000434735 | UBE3B | Q7Z3V4 | Ubiquitin-protein ligase E3B | chr12 | GO:0061630 | Not Cancer Driver | No | 151 | 0.141 | 13 | 0 | 0.0 | 1 |
| UBE3C | UBE3C | Q15386 | Ubiquitin-protein ligase E3C | chr7 | GO:0061630 | Not Cancer Driver | No | 143 | 0.132 | 65 | 12 | 0.185 | 0 |
| UBE3D | UBE3D | Q7Z6J8 | E3 ubiquitin-protein ligase E3D | chr6 | GO:0061630 | Not Cancer Driver | No | 51 | 0.131 | 9 | 3 | 0.333 | 0 |
| UBE4A_ENST00000252108 | UBE4A | Q14139 | Ubiquitin conjugation factor E4 A | chr11 | GO:0061630 | Not Cancer Driver | No | 120 | 0.113 | 121 | 17 | 0.14 | 0 |
| UBE4B | UBE4B | O95155 | Ubiquitin conjugation factor E4 B | chr1 | GO:0061630 | Not Cancer Driver | No | 158 | 0.121 | 434 | 49 | 0.113 | 0 |
| UBOX5 | UBOX5 | O94941 | RING finger protein 37 | chr20 | GO:0061630 | Not Cancer Driver | No | 62 | 0.115 | 190 | 24 | 0.126 | 0 |
| UBR1 | UBR1 | Q8IWV7 | E3 ubiquitin-protein ligase UBR1 | chr15 | GO:0061630 | Not Cancer Driver | No | 170 | 0.097 | 165 | 15 | 0.091 | 18 |
| UBR2 | UBR2 | Q8IWV8 | E3 ubiquitin-protein ligase UBR2 | chr6 | GO:0061630 | Not Cancer Driver | No | 172 | 0.098 | 228 | 30 | 0.132 | 0 |
| UBR3 | UBR3 | Q6ZT12 | E3 ubiquitin-protein ligase UBR3 | chr2 | GO:0061630 | Not Cancer Driver | No | 154 | 0.082 | 339 | 28 | 0.083 | 0 |
| UBR4 | UBR4 | Q5T4S7 | E3 ubiquitin-protein ligase UBR4 | chr1 | GO:0061630 | Not Cancer Driver | No | 565 | 0.109 | 1066 | 119 | 0.112 | 0 |
| UBR5 | UBR5 | O95071 | E3 ubiquitin-protein ligase UBR5 | chr8 | GO:0061630 | Census, Compendium | Yes | 340 | 0.121 | 1296 | 162 | 0.125 | 0 |
| UBR7 | UBR7 | Q8N806 | Putative E3 ubiquitin-protein ligase UBR7 | chr14 | GO:0061630 | Not Cancer Driver | No | 41 | 0.096 | 103 | 13 | 0.126 | 0 |
| UHRF1_ENST00000616255 | UHRF1 | Q96T88 | E3 ubiquitin-protein ligase UHRF1 | chr19 | GO:0061630 | Not Cancer Driver | No | 97 | 0.122 | 353 | 49 | 0.139 | 0 |
| UHRF2 | UHRF2 | Q96PU4 | E3 ubiquitin-protein ligase UHRF2 | chr9 | GO:0061630 | Not Cancer Driver | No | 88 | 0.11 | 253 | 22 | 0.087 | 0 |
| VPS11 | VPS11 | Q9H270 | Vacuolar protein sorting-associated protein 11 homolog | chr11 | GO:0061630 | Not Cancer Driver | No | 96 | 0.102 | 118 | 6 | 0.051 | 1 |
| VPS18 | VPS18 | Q9P253 | Vacuolar protein sorting-associated protein 18 homolog | chr15 | GO:0061630 | Not Cancer Driver | No | 96 | 0.099 | 86 | 7 | 0.081 | 0 |
| WSB1 | WSB1 | Q9Y6I7 | WD repeat and SOCS box-containing protein 1 | chr17 | GO:0061630 | Not Cancer Driver | No | 48 | 0.114 | 25 | 3 | 0.12 | 0 |
| WWP1 | WWP1 | Q9H0M0 | NEDD4-like E3 ubiquitin-protein ligase WWP1 | chr8 | GO:0061630 | Not Cancer Driver | No | 139 | 0.151 | 431 | 75 | 0.174 | 0 |
| WWP2 | WWP2 | O00308 | NEDD4-like E3 ubiquitin-protein ligase WWP2 | chr16 | GO:0061630 | Not Cancer Driver | No | 112 | 0.129 | 422 | 57 | 0.135 | 0 |
| XIAP_ENST00000434753 | XIAP | P98170 | E3 ubiquitin-protein ligase XIAP | chrX | GO:0061630 | Not Cancer Driver | No | 89 | 0.179 | 55 | 6 | 0.109 | 0 |
| ZNRF1 | ZNRF1 | Q8ND25 | E3 ubiquitin-protein ligase ZNRF1 | chr16 | GO:0061630 | Not Cancer Driver | No | 22 | 0.097 | 115 | 3 | 0.026 | 0 |
| ZNRF2 | ZNRF2 | Q8NHG8 | E3 ubiquitin-protein ligase ZNRF2 | chr7 | GO:0061630 | Not Cancer Driver | No | 12 | 0.05 | 147 | 0 | 0.0 | 0 |
| ZNRF3 | ZNRF3 | Q9ULT6 | E3 ubiquitin-protein ligase ZNRF3 | chr22 | GO:0061630 | Census, Compendium | Yes | 94 | 0.1 | 510 | 51 | 0.1 | 0 |
| ZNRF4 | ZNRF4 | Q8WWF5 | E3 ubiquitin-protein ligase ZNRF4 | chr19 | GO:0061630 | Not Cancer Driver | No | 115 | 0.268 | 99 | 26 | 0.263 | 0 |
| ZSWIM2 | ZSWIM2 | Q8NEG5 | E3 ubiquitin-protein ligase ZSWIM2 | chr2 | GO:0061630 | Not Cancer Driver | No | 189 | 0.299 | 85 | 30 | 0.353 | 0 |