Total number of protein in "GO:0061448" GO term: 48
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACAT1 | ACAT1 | P24752 | Acetyl-CoA acetyltransferase, mitochondrial | chr11 | GO:0061448 | Not Cancer Driver | No | 45 | 0.105 | 32 | 1 | 0.031 | 10 |
| AMER1 | AMER1 | Q5JTC6 | APC membrane recruitment protein 1 | chrX | GO:0061448 | Census, Compendium | Yes | 234 | 0.206 | 1039 | 219 | 0.211 | 0 |
| ARID5B | ARID5B | Q14865 | AT-rich interactive domain-containing protein 5B | chr10 | GO:0061448 | Not Cancer Driver | No | 162 | 0.136 | 769 | 95 | 0.124 | 0 |
| ARRDC3 | ARRDC3 | Q96B67 | Arrestin domain-containing protein 3 | chr5 | GO:0061448 | Not Cancer Driver | No | 52 | 0.126 | 95 | 12 | 0.126 | 0 |
| ATF2 | ATF2 | P15336 | Cyclic AMP-dependent transcription factor ATF-2 | chr2 | GO:0061448 | Not Cancer Driver | No | 65 | 0.129 | 451 | 58 | 0.129 | 0 |
| BBS4 | BBS4 | Q96RK4 | Bardet-Biedl syndrome 4 protein | chr15 | GO:0061448 | Not Cancer Driver | No | 58 | 0.112 | 110 | 16 | 0.145 | 9 |
| CASR_ENST00000638421 | CASR | P41180 | Extracellular calcium-sensing receptor | chr3 | GO:0061448 | Not Cancer Driver | No | 304 | 0.282 | 189 | 60 | 0.317 | 108 |
| CDK4 | CDK4 | P11802 | Cyclin-dependent kinase 4 | chr12 | GO:0061448 | Census, Compendium | Yes | 52 | 0.172 | 52 | 5 | 0.096 | 3 |
| COL11A1 | COL11A1 | P12107 | Collagen alpha-1(XI) chain | chr1 | GO:0061448 | Not Cancer Driver | No | 749 | 0.415 | 1436 | 617 | 0.43 | 8 |
| COL5A1 | COL5A1 | P20908 | Collagen alpha-1(V) chain | chr9 | GO:0061448 | Not Cancer Driver | No | 451 | 0.245 | 1456 | 385 | 0.264 | 7 |
| COMP | COMP | P49747 | Cartilage oligomeric matrix protein | chr19 | GO:0061448 | Not Cancer Driver | No | 97 | 0.128 | 306 | 52 | 0.17 | 61 |
| CSF1_ENST00000369802 | CSF1 | P09603 | Macrophage colony-stimulating factor 1 | chr1 | GO:0061448 | Not Cancer Driver | No | 69 | 0.125 | 339 | 46 | 0.136 | 0 |
| DGAT2 | DGAT2 | Q96PD7 | Diacylglycerol O-acyltransferase 2 | chr11 | GO:0061448 | Not Cancer Driver | No | 56 | 0.144 | 17 | 2 | 0.118 | 0 |
| DHRS7B | DHRS7B | Q6IAN0 | Dehydrogenase/reductase SDR family member 7B | chr17 | GO:0061448 | Not Cancer Driver | No | 37 | 0.114 | 17 | 0 | 0.0 | 0 |
| DYRK1B_ENST00000323039 | DYRK1B | Q9Y463 | Dual specificity tyrosine-phosphorylation-regulated kinase 1B | chr19 | GO:0061448 | Not Cancer Driver | No | 77 | 0.122 | 319 | 38 | 0.119 | 2 |
| EBF2 | EBF2 | Q9HAK2 | Transcription factor COE2 | chr8 | GO:0061448 | Not Cancer Driver | No | 158 | 0.275 | 261 | 71 | 0.272 | 0 |
| FOXD1 | FOXD1 | Q16676 | Forkhead box protein D1 | chr5 | GO:0061448 | Not Cancer Driver | No | 10 | 0.022 | 259 | 5 | 0.019 | 0 |
| FTO | FTO | Q9C0B1 | Alpha-ketoglutarate-dependent dioxygenase FTO | chr16 | GO:0061448 | Not Cancer Driver | No | 67 | 0.133 | 53 | 10 | 0.189 | 3 |
| HMGCS2 | HMGCS2 | P54868 | Hydroxymethylglutaryl-CoA synthase, mitochondrial | chr1 | GO:0061448 | Not Cancer Driver | No | 92 | 0.181 | 29 | 4 | 0.138 | 19 |
| LEP | LEP | P41159 | Leptin | chr7 | GO:0061448 | Not Cancer Driver | No | 29 | 0.174 | 0 | 0 | 0.0 | 2 |
| LOX | LOX | P28300 | Protein-lysine 6-oxidase | chr5 | GO:0061448 | Compendium | Yes | 44 | 0.106 | 172 | 11 | 0.064 | 4 |
| LRP5 | LRP5 | O75197 | Low-density lipoprotein receptor-related protein 5 | chr11 | GO:0061448 | Not Cancer Driver | No | 253 | 0.157 | 188 | 28 | 0.149 | 55 |
| LRP5L_ENST00000402785 | LRP5L | A4QPB2 | Low-density lipoprotein receptor-related protein 5-like protein | chr22 | GO:0061448 | Not Cancer Driver | No | 38 | 0.151 | 39 | 5 | 0.128 | 0 |
| MMP13 | MMP13 | P45452 | Collagenase 3 | chr11 | GO:0061448 | Not Cancer Driver | No | 113 | 0.24 | 59 | 16 | 0.271 | 5 |
| NAMPT | NAMPT | P43490 | Nicotinamide phosphoribosyltransferase | chr7 | GO:0061448 | Not Cancer Driver | No | 50 | 0.102 | 27 | 5 | 0.185 | 0 |
| OXCT1 | OXCT1 | P55809 | Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial | chr5 | GO:0061448 | Not Cancer Driver | No | 80 | 0.154 | 39 | 5 | 0.128 | 11 |
| PAXIP1 | PAXIP1 | Q6ZW49 | PAX-interacting protein 1 | chr7 | GO:0061448 | Not Cancer Driver | No | 120 | 0.112 | 461 | 39 | 0.085 | 0 |
| PGRMC2_ENST00000296425 | PGRMC2 | O15173 | Membrane-associated progesterone receptor component 2 | chr4 | GO:0061448 | Not Cancer Driver | No | 16 | 0.072 | 83 | 4 | 0.048 | 0 |
| PIK3CA | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | GO:0061448 | Census, Compendium | Yes | 1669 | 1.563 | 38 | 11 | 0.289 | 30 |
| PPARD_ENST00000360694 | PPARD | Q03181 | Peroxisome proliferator-activated receptor delta | chr6 | GO:0061448 | Not Cancer Driver | No | 72 | 0.163 | 69 | 7 | 0.101 | 0 |
| PPARGC1A | PPARGC1A | Q9UBK2 | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha | chr4 | GO:0061448 | Not Cancer Driver | No | 181 | 0.227 | 609 | 148 | 0.243 | 0 |
| RARA | RARA | P10276 | Retinoic acid receptor alpha | chr17 | GO:0061448 | Census, Compendium | Yes | 70 | 0.152 | 167 | 14 | 0.084 | 0 |
| RORC | RORC | P51449 | Nuclear receptor ROR-gamma | chr1 | GO:0061448 | Not Cancer Driver | No | 96 | 0.185 | 187 | 36 | 0.193 | 1 |
| RXFP1_ENST00000307765 | RXFP1 | Q9HBX9 | Relaxin receptor 1 | chr4 | GO:0061448 | Not Cancer Driver | No | 152 | 0.201 | 0 | 0 | 0.0 | 0 |
| SELENOM_ENST00000611680 | SELENOM | Q8WWX9 | Selenoprotein M | chr22 | GO:0061448 | Not Cancer Driver | No | 10 | 0.069 | 21 | 2 | 0.095 | 0 |
| SH3PXD2B | SH3PXD2B | A1X283 | SH3 and PX domain-containing protein 2B | chr5 | GO:0061448 | Not Cancer Driver | No | 122 | 0.134 | 660 | 101 | 0.153 | 1 |
| SLC25A25_ENST00000373064 | SLC25A25 | Q6KCM7 | Calcium-binding mitochondrial carrier protein SCaMC-2 | chr9 | GO:0061448 | Not Cancer Driver | No | 45 | 0.096 | 5 | 1 | 0.2 | 0 |
| SLC39A13 | SLC39A13 | Q96H72 | Zinc transporter ZIP13 | chr11 | GO:0061448 | Not Cancer Driver | No | 39 | 0.105 | 18 | 2 | 0.111 | 0 |
| SOX8 | SOX8 | P57073 | Transcription factor SOX-8 | chr16 | GO:0061448 | Not Cancer Driver | No | 43 | 0.096 | 403 | 39 | 0.097 | 0 |
| SPART_ENST00000355182 | SPART | Q8N0X7 | Spartin | chr13 | GO:0061448 | Not Cancer Driver | No | 112 | 0.168 | 396 | 68 | 0.172 | 1 |
| SPTLC2 | SPTLC2 | O15270 | Serine palmitoyltransferase 2 | chr14 | GO:0061448 | Not Cancer Driver | No | 72 | 0.128 | 9 | 2 | 0.222 | 5 |
| TBL1XR1 | TBL1XR1 | Q9BZK7 | F-box-like/WD repeat-containing protein TBL1XR1 | chr3 | GO:0061448 | Census, Compendium | Yes | 82 | 0.16 | 136 | 19 | 0.14 | 4 |
| THBS3 | THBS3 | P49746 | Thrombospondin-3 | chr1 | GO:0061448 | Not Cancer Driver | No | 100 | 0.105 | 283 | 24 | 0.085 | 0 |
| UBB_ENST00000614404 | UBB | P0CG47 | Polyubiquitin-B | chr17 | GO:0061448 | Not Cancer Driver | No | 20 | 0.087 | 102 | 8 | 0.078 | 0 |
| UMODL1_ENST00000408910 | UMODL1 | Q5DID0 | Uromodulin-like 1 | chr21 | GO:0061448 | Not Cancer Driver | No | 191 | 0.145 | 249 | 29 | 0.116 | 0 |
| XBP1 | XBP1 | P17861 | X-box-binding protein 1 | chr22 | GO:0061448 | Not Cancer Driver | No | 19 | 0.073 | 169 | 9 | 0.053 | 0 |
| ZMPSTE24 | ZMPSTE24 | O75844 | CAAX prenyl protease 1 homolog | chr1 | GO:0061448 | Not Cancer Driver | No | 67 | 0.141 | 23 | 0 | 0.0 | 3 |
| ZNF516 | ZNF516 | Q92618 | Zinc finger protein 516 | chr18 | GO:0061448 | Not Cancer Driver | No | 177 | 0.152 | 861 | 131 | 0.152 | 0 |