Total number of protein in "GO:0061134" GO term: 90
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADRM1 | ADRM1 | Q16186 | Proteasomal ubiquitin receptor ADRM1 | chr20 | GO:0061134 | Not Cancer Driver | No | 49 | 0.12 | 296 | 40 | 0.135 | 0 |
| APAF1 | APAF1 | O14727 | Apoptotic protease-activating factor 1 | chr12 | GO:0061134 | Not Cancer Driver | No | 127 | 0.102 | 17 | 1 | 0.059 | 0 |
| APH1A | APH1A | Q96BI3 | Gamma-secretase subunit APH-1A | chr1 | GO:0061134 | Not Cancer Driver | No | 32 | 0.121 | 0 | 0 | 0.0 | 0 |
| APH1B | APH1B | Q8WW43 | Gamma-secretase subunit APH-1B | chr15 | GO:0061134 | Not Cancer Driver | No | 21 | 0.082 | 0 | 0 | 0.0 | 0 |
| APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | GO:0061134 | Not Cancer Driver | No | 128 | 0.166 | 418 | 71 | 0.17 | 17 |
| ATP2A3_ENST00000397041 | ATP2A3 | Q93084 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 | chr17 | GO:0061134 | Not Cancer Driver | No | 130 | 0.13 | 147 | 16 | 0.109 | 0 |
| AVP | AVP | P01185 | Vasopressin-neurophysin 2-copeptin | chr20 | GO:0061134 | Not Cancer Driver | No | 14 | 0.085 | 26 | 0 | 0.0 | 39 |
| BAD_ENST00000309032 | BAD | Q92934 | Bcl2-associated agonist of cell death | chr11 | GO:0061134 | Not Cancer Driver | No | 14 | 0.083 | 163 | 14 | 0.086 | 0 |
| BCL2L13_ENST00000317582 | BCL2L13 | Q9BXK5 | Bcl-2-like protein 13 | chr22 | GO:0061134 | Not Cancer Driver | No | 49 | 0.101 | 291 | 30 | 0.103 | 0 |
| BEX3_ENST00000372635 | BEX3 | Q00994 | Protein BEX3 | chrX | GO:0061134 | Not Cancer Driver | No | 19 | 0.171 | 98 | 17 | 0.173 | 0 |
| BIN1 | BIN1 | O00499 | Myc box-dependent-interacting protein 1 | chr2 | GO:0061134 | Not Cancer Driver | No | 65 | 0.11 | 456 | 42 | 0.092 | 5 |
| BIRC2 | BIRC2 | Q13490 | Baculoviral IAP repeat-containing protein 2 | chr11 | GO:0061134 | Not Cancer Driver | No | 69 | 0.112 | 83 | 9 | 0.108 | 0 |
| BIRC3_ENST00000532808 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | GO:0061134 | Census, Compendium | Yes | 77 | 0.127 | 98 | 16 | 0.163 | 0 |
| BIRC5_ENST00000350051 | BIRC5 | O15392 | Baculoviral IAP repeat-containing protein 5 | chr17 | GO:0061134 | Not Cancer Driver | No | 20 | 0.141 | 49 | 6 | 0.122 | 0 |
| BIRC7 | BIRC7 | Q96CA5 | Baculoviral IAP repeat-containing protein 7 | chr20 | GO:0061134 | Not Cancer Driver | No | 52 | 0.174 | 136 | 22 | 0.162 | 0 |
| BIRC8 | BIRC8 | Q96P09 | Baculoviral IAP repeat-containing protein 8 | chr19 | GO:0061134 | Not Cancer Driver | No | 79 | 0.335 | 39 | 10 | 0.256 | 0 |
| BST2 | BST2 | Q10589 | Bone marrow stromal antigen 2 | chr19 | GO:0061134 | Not Cancer Driver | No | 19 | 0.106 | 20 | 0 | 0.0 | 0 |
| CARD8_ENST00000519940 | CARD8 | Q9Y2G2 | Caspase recruitment domain-containing protein 8 | chr19 | GO:0061134 | Not Cancer Driver | No | 53 | 0.099 | 126 | 7 | 0.056 | 1 |
| CASP1 | CASP1 | P29466 | Caspase-1 | chr11 | GO:0061134 | Not Cancer Driver | No | 79 | 0.196 | 87 | 18 | 0.207 | 0 |
| CASP8AP2 | CASP8AP2 | Q9UKL3 | CASP8-associated protein 2 | chr6 | GO:0061134 | Not Cancer Driver | No | 219 | 0.11 | 1501 | 178 | 0.119 | 0 |
| CAST_ENST00000395813 | CAST | P20810 | Calpastatin | chr5 | GO:0061134 | Not Cancer Driver | No | 73 | 0.103 | 708 | 73 | 0.103 | 0 |
| CAV1 | CAV1 | Q03135 | Caveolin-1 | chr7 | GO:0061134 | Not Cancer Driver | No | 30 | 0.169 | 2 | 0 | 0.0 | 0 |
| CD27 | CD27 | P26842 | CD27 antigen | chr12 | GO:0061134 | Not Cancer Driver | No | 30 | 0.115 | 92 | 11 | 0.12 | 1 |
| CLPX | CLPX | O76031 | ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial | chr15 | GO:0061134 | Not Cancer Driver | No | 66 | 0.104 | 195 | 22 | 0.113 | 1 |
| COL4A3 | COL4A3 | Q01955 | Collagen alpha-3(IV) chain | chr2 | GO:0061134 | Not Cancer Driver | No | 310 | 0.186 | 1433 | 277 | 0.193 | 13 |
| CRB2 | CRB2 | Q5IJ48 | Protein crumbs homolog 2 | chr9 | GO:0061134 | Not Cancer Driver | No | 155 | 0.121 | 72 | 0 | 0.0 | 5 |
| CTSC | CTSC | P53634 | Dipeptidyl peptidase 1 | chr11 | GO:0061134 | Not Cancer Driver | No | 64 | 0.138 | 19 | 5 | 0.263 | 29 |
| CTSH | CTSH | P09668 | Pro-cathepsin H | chr15 | GO:0061134 | Not Cancer Driver | No | 45 | 0.134 | 4 | 0 | 0.0 | 0 |
| DPEP1 | DPEP1 | P16444 | Dipeptidase 1 | chr16 | GO:0061134 | Not Cancer Driver | No | 54 | 0.131 | 41 | 6 | 0.146 | 0 |
| EBAG9_ENST00000620557 | EBAG9 | O00559 | Receptor-binding cancer antigen expressed on SiSo cells | chr8 | GO:0061134 | Not Cancer Driver | No | 35 | 0.164 | 173 | 29 | 0.168 | 0 |
| FBLN1 | FBLN1 | P23142 | Fibulin-1 | chr22 | GO:0061134 | Compendium | Yes | 122 | 0.174 | 22 | 3 | 0.136 | 0 |
| FETUB_ENST00000450521 | FETUB | Q9UGM5 | Fetuin-B | chr3 | GO:0061134 | Not Cancer Driver | No | 76 | 0.199 | 119 | 30 | 0.252 | 0 |
| FN1 | FN1 | P02751 | Fibronectin | chr2 | GO:0061134 | Compendium | Yes | 394 | 0.159 | 1243 | 185 | 0.149 | 8 |
| GAPDH | GAPDH | P04406 | Glyceraldehyde-3-phosphate dehydrogenase | chr12 | GO:0061134 | Not Cancer Driver | No | 39 | 0.116 | 24 | 3 | 0.125 | 0 |
| GAS6 | GAS6 | Q14393 | Growth arrest-specific protein 6 | chr13 | GO:0061134 | Not Cancer Driver | No | 82 | 0.121 | 42 | 6 | 0.143 | 0 |
| GPC3_ENST00000370818 | GPC3 | P51654 | Glypican-3 | chrX | GO:0061134 | Census | Yes | 89 | 0.153 | 86 | 11 | 0.128 | 1 |
| LXN | LXN | Q9BS40 | Latexin | chr3 | GO:0061134 | Not Cancer Driver | No | 21 | 0.095 | 91 | 9 | 0.099 | 0 |
| MAL | MAL | P21145 | Myelin and lymphocyte protein | chr2 | GO:0061134 | Not Cancer Driver | No | 21 | 0.137 | 0 | 0 | 0.0 | 0 |
| MT3 | MT3 | P25713 | Metallothionein-3 | chr16 | GO:0061134 | Not Cancer Driver | No | 7 | 0.103 | 0 | 0 | 0.0 | 0 |
| NAIP_ENST00000194097 | NAIP | Q13075 | Baculoviral IAP repeat-containing protein 1 | chr5 | GO:0061134 | Not Cancer Driver | No | 39 | 0.028 | 67 | 4 | 0.06 | 0 |
| NGF | NGF | P01138 | Beta-nerve growth factor | chr1 | GO:0061134 | Not Cancer Driver | No | 66 | 0.274 | 93 | 25 | 0.269 | 1 |
| NKX3-1 | NKX3-1 | Q99801 | Homeobox protein Nkx-3.1 | chr8 | GO:0061134 | Not Cancer Driver | No | 35 | 0.15 | 171 | 16 | 0.094 | 0 |
| NLRC4_ENST00000360906 | NLRC4 | Q9NPP4 | NLR family CARD domain-containing protein 4 | chr2 | GO:0061134 | Not Cancer Driver | No | 205 | 0.2 | 15 | 2 | 0.133 | 3 |
| NLRP12_ENST00000324134 | NLRP12 | P59046 | NACHT, LRR and PYD domains-containing protein 12 | chr19 | GO:0061134 | Not Cancer Driver | No | 310 | 0.292 | 116 | 43 | 0.371 | 0 |
| NLRP1_ENST00000572272 | NLRP1 | Q9C000 | NACHT, LRR and PYD domains-containing protein 1 | chr17 | GO:0061134 | Not Cancer Driver | No | 222 | 0.151 | 340 | 65 | 0.191 | 6 |
| NLRP7_ENST00000590030 | NLRP7 | Q8WX94 | NACHT, LRR and PYD domains-containing protein 7 | chr19 | GO:0061134 | Not Cancer Driver | No | 300 | 0.306 | 71 | 20 | 0.282 | 9 |
| NOD1 | NOD1 | Q9Y239 | Nucleotide-binding oligomerization domain-containing protein 1 | chr7 | GO:0061134 | Not Cancer Driver | No | 130 | 0.136 | 38 | 7 | 0.184 | 0 |
| NOL3_ENST00000268605 | NOL3 | O60936 | Nucleolar protein 3 | chr16 | GO:0061134 | Not Cancer Driver | No | 20 | 0.096 | 179 | 17 | 0.095 | 2 |
| PCOLCE | PCOLCE | Q15113 | Procollagen C-endopeptidase enhancer 1 | chr7 | GO:0061134 | Not Cancer Driver | No | 46 | 0.102 | 187 | 18 | 0.096 | 0 |
| PCOLCE2 | PCOLCE2 | Q9UKZ9 | Procollagen C-endopeptidase enhancer 2 | chr3 | GO:0061134 | Not Cancer Driver | No | 102 | 0.246 | 25 | 3 | 0.12 | 0 |
| PINK1 | PINK1 | Q9BXM7 | Serine/threonine-protein kinase PINK1, mitochondrial | chr1 | GO:0061134 | Not Cancer Driver | No | 57 | 0.098 | 99 | 13 | 0.131 | 23 |
| PRDX3 | PRDX3 | P30048 | Thioredoxin-dependent peroxide reductase, mitochondrial | chr10 | GO:0061134 | Not Cancer Driver | No | 23 | 0.09 | 23 | 3 | 0.13 | 0 |
| PRDX5 | PRDX5 | P30044 | Peroxiredoxin-5, mitochondrial | chr11 | GO:0061134 | Not Cancer Driver | No | 22 | 0.103 | 0 | 0 | 0.0 | 0 |
| PRNP | PRNP | P04156 | Major prion protein | chr20 | GO:0061134 | Not Cancer Driver | No | 36 | 0.142 | 115 | 7 | 0.061 | 18 |
| PRSS22 | PRSS22 | Q9GZN4 | Brain-specific serine protease 4 | chr16 | GO:0061134 | Not Cancer Driver | No | 37 | 0.117 | 28 | 5 | 0.179 | 0 |
| PSENEN_ENST00000222266 | PSENEN | Q9NZ42 | Gamma-secretase subunit PEN-2 | chr19 | GO:0061134 | Not Cancer Driver | No | 17 | 0.168 | 0 | 0 | 0.0 | 0 |
| PSMD14 | PSMD14 | O00487 | 26S proteasome non-ATPase regulatory subunit 14 | chr2 | GO:0061134 | Not Cancer Driver | No | 23 | 0.074 | 67 | 6 | 0.09 | 0 |
| PSME1_ENST00000206451 | PSME1 | Q06323 | Proteasome activator complex subunit 1 | chr14 | GO:0061134 | Not Cancer Driver | No | 20 | 0.08 | 80 | 8 | 0.1 | 0 |
| PSME2 | PSME2 | Q9UL46 | Proteasome activator complex subunit 2 | chr14 | GO:0061134 | Not Cancer Driver | No | 32 | 0.134 | 39 | 3 | 0.077 | 0 |
| PSME3_ENST00000590720 | PSME3 | P61289 | Proteasome activator complex subunit 3 | chr17 | GO:0061134 | Not Cancer Driver | No | 20 | 0.079 | 25 | 5 | 0.2 | 0 |
| PSME4 | PSME4 | Q14997 | Proteasome activator complex subunit 4 | chr2 | GO:0061134 | Not Cancer Driver | No | 214 | 0.116 | 134 | 12 | 0.09 | 0 |
| PYCARD | PYCARD | Q9ULZ3 | Apoptosis-associated speck-like protein containing a CARD | chr16 | GO:0061134 | Not Cancer Driver | No | 16 | 0.082 | 39 | 4 | 0.103 | 0 |
| RACK1 | RACK1 | P63244 | Receptor of activated protein C kinase 1 | chr5 | GO:0061134 | Not Cancer Driver | No | 34 | 0.107 | 13 | 0 | 0.0 | 0 |
| RARRES1 | RARRES1 | P49788 | Retinoic acid receptor responder protein 1 | chr3 | GO:0061134 | Not Cancer Driver | No | 24 | 0.082 | 79 | 3 | 0.038 | 0 |
| RECK | RECK | O95980 | Reversion-inducing cysteine-rich protein with Kazal motifs | chr9 | GO:0061134 | Not Cancer Driver | No | 115 | 0.118 | 9 | 2 | 0.222 | 0 |
| ROCK1 | ROCK1 | Q13464 | Rho-associated protein kinase 1 | chr18 | GO:0061134 | Not Cancer Driver | No | 184 | 0.136 | 780 | 103 | 0.132 | 0 |
| RPS27L | RPS27L | Q71UM5 | 40S ribosomal protein S27-like | chr15 | GO:0061134 | Not Cancer Driver | No | 4 | 0.048 | 22 | 2 | 0.091 | 0 |
| RPS6KA1_ENST00000374168 | RPS6KA1 | Q15418 | Ribosomal protein S6 kinase alpha-1 | chr1 | GO:0061134 | Not Cancer Driver | No | 94 | 0.128 | 178 | 32 | 0.18 | 0 |
| RPS6KA3_ENST00000379565 | RPS6KA3 | P51812 | Ribosomal protein S6 kinase alpha-3 | chrX | GO:0061134 | Compendium | Yes | 106 | 0.143 | 145 | 18 | 0.124 | 13 |
| SERPINB9 | SERPINB9 | P50453 | Serpin B9 | chr6 | GO:0061134 | Not Cancer Driver | No | 64 | 0.17 | 22 | 2 | 0.091 | 0 |
| SFRP2 | SFRP2 | Q96HF1 | Secreted frizzled-related protein 2 | chr4 | GO:0061134 | Not Cancer Driver | No | 47 | 0.159 | 1 | 0 | 0.0 | 0 |
| SNCA_ENST00000506244 | SNCA | P37840 | Alpha-synuclein | chr4 | GO:0061134 | Not Cancer Driver | No | 21 | 0.15 | 107 | 13 | 0.121 | 5 |
| SPOCK1 | SPOCK1 | Q08629 | Testican-1 | chr5 | GO:0061134 | Not Cancer Driver | No | 82 | 0.187 | 107 | 16 | 0.15 | 0 |
| SPOCK2_ENST00000317376 | SPOCK2 | Q92563 | Testican-2 | chr10 | GO:0061134 | Not Cancer Driver | No | 48 | 0.113 | 113 | 8 | 0.071 | 0 |
| SPOCK3_ENST00000511531 | SPOCK3 | Q9BQ16 | Testican-3 | chr4 | GO:0061134 | Not Cancer Driver | No | 132 | 0.303 | 68 | 38 | 0.559 | 0 |
| ST20_ENST00000562759 | ST20 | Q9HBF5 | Suppressor of tumorigenicity 20 protein | chr15 | GO:0061134 | Not Cancer Driver | No | 17 | 0.215 | 0 | 0 | 0.0 | 0 |
| TANK | TANK | Q92844 | TRAF family member-associated NF-kappa-B activator | chr2 | GO:0061134 | Not Cancer Driver | No | 42 | 0.099 | 302 | 26 | 0.086 | 0 |
| TIMP1 | TIMP1 | P01033 | Metalloproteinase inhibitor 1 | chrX | GO:0061134 | Not Cancer Driver | No | 25 | 0.121 | 0 | 0 | 0.0 | 0 |
| TIMP2 | TIMP2 | P16035 | Metalloproteinase inhibitor 2 | chr17 | GO:0061134 | Not Cancer Driver | No | 31 | 0.141 | 6 | 2 | 0.333 | 0 |
| TIMP3 | TIMP3 | P35625 | Metalloproteinase inhibitor 3 | chr22 | GO:0061134 | Not Cancer Driver | No | 43 | 0.204 | 3 | 1 | 0.333 | 5 |
| TIMP4 | TIMP4 | Q99727 | Metalloproteinase inhibitor 4 | chr3 | GO:0061134 | Not Cancer Driver | No | 30 | 0.134 | 8 | 2 | 0.25 | 0 |
| TNFAIP8_ENST00000504771 | TNFAIP8 | O95379 | Tumor necrosis factor alpha-induced protein 8 | chr5 | GO:0061134 | Not Cancer Driver | No | 21 | 0.106 | 13 | 1 | 0.077 | 0 |
| TNFSF14 | TNFSF14 | O43557 | Tumor necrosis factor ligand superfamily member 14 | chr19 | GO:0061134 | Not Cancer Driver | No | 58 | 0.242 | 18 | 1 | 0.056 | 0 |
| VCP | VCP | P55072 | Transitional endoplasmic reticulum ATPase | chr9 | GO:0061134 | Not Cancer Driver | No | 88 | 0.109 | 186 | 16 | 0.086 | 16 |
| VIL1 | VIL1 | P09327 | Villin-1 | chr2 | GO:0061134 | Not Cancer Driver | No | 124 | 0.15 | 222 | 38 | 0.171 | 0 |
| VSIR | VSIR | Q9H7M9 | V-type immunoglobulin domain-containing suppressor of T-cell activation | chr10 | GO:0061134 | Not Cancer Driver | No | 52 | 0.167 | 135 | 19 | 0.141 | 0 |
| WFDC2 | WFDC2 | Q14508 | WAP four-disulfide core domain protein 2 | chr20 | GO:0061134 | Not Cancer Driver | No | 16 | 0.129 | 0 | 0 | 0.0 | 0 |
| WFIKKN1 | WFIKKN1 | Q96NZ8 | WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 | chr16 | GO:0061134 | Not Cancer Driver | No | 38 | 0.069 | 90 | 4 | 0.044 | 0 |
| WFIKKN2 | WFIKKN2 | Q8TEU8 | WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 | chr17 | GO:0061134 | Not Cancer Driver | No | 114 | 0.198 | 94 | 32 | 0.34 | 0 |
| XIAP_ENST00000434753 | XIAP | P98170 | E3 ubiquitin-protein ligase XIAP | chrX | GO:0061134 | Not Cancer Driver | No | 89 | 0.179 | 55 | 6 | 0.109 | 0 |