Total number of protein in "GO:0060560" GO term: 59
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0060560 | Census, Compendium | Yes | 139 | 0.123 | 604 | 73 | 0.121 | 2 |
| ADPRHL1 | ADPRHL1 | Q8NDY3 | Inactive ADP-ribosyltransferase ARH2 | chr13 | GO:0060560 | Not Cancer Driver | No | 52 | 0.147 | 32 | 7 | 0.219 | 0 |
| ALCAM | ALCAM | Q13740 | CD166 antigen | chr3 | GO:0060560 | Not Cancer Driver | No | 89 | 0.153 | 96 | 19 | 0.198 | 0 |
| APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | GO:0060560 | Not Cancer Driver | No | 128 | 0.166 | 418 | 71 | 0.17 | 17 |
| AUTS2 | AUTS2 | Q8WXX7 | Autism susceptibility gene 2 protein | chr7 | GO:0060560 | Not Cancer Driver | No | 219 | 0.174 | 1218 | 213 | 0.175 | 0 |
| BDNF_ENST00000439476 | BDNF | P23560 | Brain-derived neurotrophic factor | chr11 | GO:0060560 | Not Cancer Driver | No | 47 | 0.19 | 79 | 19 | 0.241 | 1 |
| BMP4 | BMP4 | P12644 | Bone morphogenetic protein 4 | chr14 | GO:0060560 | Not Cancer Driver | No | 86 | 0.211 | 142 | 26 | 0.183 | 5 |
| CCL11 | CCL11 | P51671 | Eotaxin | chr17 | GO:0060560 | Not Cancer Driver | No | 18 | 0.186 | 14 | 3 | 0.214 | 0 |
| CDKL3 | CDKL3 | Q8IVW4 | Cyclin-dependent kinase-like 3 | chr5 | GO:0060560 | Not Cancer Driver | No | 68 | 0.115 | 278 | 40 | 0.144 | 0 |
| COBL_ENST00000265136 | COBL | O75128 | Protein cordon-bleu | chr7 | GO:0060560 | Not Cancer Driver | No | 233 | 0.185 | 1149 | 216 | 0.188 | 0 |
| CSF1_ENST00000369802 | CSF1 | P09603 | Macrophage colony-stimulating factor 1 | chr1 | GO:0060560 | Not Cancer Driver | No | 69 | 0.125 | 339 | 46 | 0.136 | 0 |
| CYFIP1_ENST00000610365 | CYFIP1 | Q7L576 | Cytoplasmic FMR1-interacting protein 1 | chr15 | GO:0060560 | Not Cancer Driver | No | 46 | 0.037 | 96 | 0 | 0.0 | 0 |
| CYFIP2 | CYFIP2 | Q96F07 | Cytoplasmic FMR1-interacting protein 2 | chr5 | GO:0060560 | Not Cancer Driver | No | 211 | 0.165 | 86 | 11 | 0.128 | 3 |
| DVL1 | DVL1 | O14640 | Segment polarity protein dishevelled homolog DVL-1 | chr1 | GO:0060560 | Not Cancer Driver | No | 73 | 0.105 | 434 | 38 | 0.088 | 0 |
| EDN2 | EDN2 | P20800 | Endothelin-2 | chr1 | GO:0060560 | Not Cancer Driver | No | 21 | 0.118 | 87 | 13 | 0.149 | 0 |
| EFNA5 | EFNA5 | P52803 | Ephrin-A5 | chr5 | GO:0060560 | Not Cancer Driver | No | 34 | 0.149 | 25 | 6 | 0.24 | 0 |
| ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | GO:0060560 | Census, Compendium | Yes | 121 | 0.203 | 195 | 27 | 0.138 | 2 |
| EXT1 | EXT1 | Q16394 | Exostosin-1 | chr8 | GO:0060560 | Census | Yes | 107 | 0.143 | 58 | 7 | 0.121 | 12 |
| FGF10 | FGF10 | O15520 | Fibroblast growth factor 10 | chr5 | GO:0060560 | Not Cancer Driver | No | 56 | 0.269 | 34 | 11 | 0.324 | 2 |
| FGF1_ENST00000612258 | FGF1 | P05230 | Fibroblast growth factor 1 | chr5 | GO:0060560 | Not Cancer Driver | No | 30 | 0.194 | 29 | 2 | 0.069 | 0 |
| FGFR2_ENST00000358487 | FGFR2 | P21802 | Fibroblast growth factor receptor 2 | chr10 | GO:0060560 | Census, Compendium | Yes | 238 | 0.29 | 228 | 44 | 0.193 | 72 |
| FMN1 | FMN1 | Q68DA7 | Formin-1 | chr15 | GO:0060560 | Not Cancer Driver | No | 117 | 0.082 | 983 | 67 | 0.068 | 0 |
| HDAC6_ENST00000426196 | HDAC6 | Q9UBN7 | Histone deacetylase 6 | chrX | GO:0060560 | Not Cancer Driver | No | 178 | 0.147 | 409 | 59 | 0.144 | 0 |
| HOXD13 | HOXD13 | P35453 | Homeobox protein Hox-D13 | chr2 | GO:0060560 | Census, Compendium | Yes | 43 | 0.125 | 113 | 12 | 0.106 | 9 |
| KDM5B_ENST00000367265 | KDM5B | Q9UGL1 | Lysine-specific demethylase 5B | chr1 | GO:0060560 | Not Cancer Driver | No | 219 | 0.142 | 388 | 58 | 0.149 | 0 |
| KIF26B | KIF26B | Q2KJY2 | Kinesin-like protein KIF26B | chr1 | GO:0060560 | Not Cancer Driver | No | 369 | 0.175 | 1412 | 198 | 0.14 | 0 |
| LAMB2 | LAMB2 | P55268 | Laminin subunit beta-2 | chr3 | GO:0060560 | Not Cancer Driver | No | 234 | 0.13 | 463 | 67 | 0.145 | 9 |
| LLPH_ENST00000446587 | LLPH | Q9BRT6 | Protein LLP homolog | chr12 | GO:0060560 | Not Cancer Driver | No | 15 | 0.116 | 113 | 14 | 0.124 | 0 |
| LZTS2 | LZTS2 | Q9BRK4 | Leucine zipper putative tumor suppressor 2 | chr10 | GO:0060560 | Not Cancer Driver | No | 78 | 0.117 | 508 | 66 | 0.13 | 0 |
| MED12 | MED12 | Q93074 | Mediator of RNA polymerase II transcription subunit 12 | chrX | GO:0060560 | Census, Compendium | Yes | 409 | 0.188 | 974 | 175 | 0.18 | 5 |
| MESP1 | MESP1 | Q9BRJ9 | Mesoderm posterior protein 1 | chr15 | GO:0060560 | Not Cancer Driver | No | 8 | 0.03 | 247 | 7 | 0.028 | 0 |
| NIN | NIN | Q8N4C6 | Ninein | chr14 | GO:0060560 | Census, Compendium | Yes | 239 | 0.114 | 1392 | 164 | 0.118 | 2 |
| NOTCH1 | NOTCH1 | P46531 | Neurogenic locus notch homolog protein 1 | chr9 | GO:0060560 | Census, Compendium | Yes | 363 | 0.142 | 686 | 87 | 0.127 | 3 |
| NRP1 | NRP1 | O14786 | Neuropilin-1 | chr10 | GO:0060560 | Compendium | Yes | 146 | 0.158 | 211 | 31 | 0.147 | 0 |
| NRP2 | NRP2 | O60462 | Neuropilin-2 | chr2 | GO:0060560 | Not Cancer Driver | No | 161 | 0.173 | 207 | 45 | 0.217 | 0 |
| PTK7_ENST00000230419 | PTK7 | Q13308 | Inactive tyrosine-protein kinase 7 | chr6 | GO:0060560 | Not Cancer Driver | No | 153 | 0.143 | 359 | 58 | 0.162 | 0 |
| RARG | RARG | P13631 | Retinoic acid receptor gamma | chr12 | GO:0060560 | Not Cancer Driver | No | 82 | 0.181 | 164 | 24 | 0.146 | 0 |
| RDH10 | RDH10 | Q8IZV5 | Retinol dehydrogenase 10 | chr8 | GO:0060560 | Not Cancer Driver | No | 33 | 0.097 | 8 | 0 | 0.0 | 0 |
| S1PR1 | S1PR1 | P21453 | Sphingosine 1-phosphate receptor 1 | chr1 | GO:0060560 | Not Cancer Driver | No | 86 | 0.225 | 29 | 6 | 0.207 | 0 |
| SALL1 | SALL1 | Q9NSC2 | Sal-like protein 1 | chr16 | GO:0060560 | Not Cancer Driver | No | 454 | 0.343 | 949 | 334 | 0.352 | 0 |
| SEMA3A | SEMA3A | Q14563 | Semaphorin-3A | chr7 | GO:0060560 | Not Cancer Driver | No | 195 | 0.253 | 164 | 46 | 0.28 | 10 |
| SEMA3F | SEMA3F | Q13275 | Semaphorin-3F | chr3 | GO:0060560 | Not Cancer Driver | No | 114 | 0.145 | 194 | 27 | 0.139 | 0 |
| SH3GL2 | SH3GL2 | Q99962 | Endophilin-A1 | chr9 | GO:0060560 | Not Cancer Driver | No | 76 | 0.216 | 214 | 50 | 0.234 | 0 |
| SHH | SHH | Q15465 | Sonic hedgehog protein | chr7 | GO:0060560 | Not Cancer Driver | No | 56 | 0.121 | 139 | 14 | 0.101 | 81 |
| SLC9A6_ENST00000370698 | SLC9A6 | Q92581 | Sodium/hydrogen exchanger 6 | chrX | GO:0060560 | Not Cancer Driver | No | 98 | 0.146 | 109 | 19 | 0.174 | 1 |
| SLIT1 | SLIT1 | O75093 | Slit homolog 1 protein | chr10 | GO:0060560 | Not Cancer Driver | No | 221 | 0.144 | 36 | 1 | 0.028 | 0 |
| SLIT2 | SLIT2 | O94813 | Slit homolog 2 protein | chr4 | GO:0060560 | Not Cancer Driver | No | 428 | 0.28 | 31 | 13 | 0.419 | 0 |
| SLIT3_ENST00000519560 | SLIT3 | O75094 | Slit homolog 3 protein | chr5 | GO:0060560 | Not Cancer Driver | No | 351 | 0.23 | 40 | 9 | 0.225 | 0 |
| SOX9 | SOX9 | P48436 | Transcription factor SOX-9 | chr17 | GO:0060560 | Compendium | Yes | 86 | 0.169 | 495 | 82 | 0.166 | 18 |
| SPRY1 | SPRY1 | O43609 | Protein sprouty homolog 1 | chr4 | GO:0060560 | Not Cancer Driver | No | 46 | 0.144 | 168 | 26 | 0.155 | 0 |
| SPRY2 | SPRY2 | O43597 | Protein sprouty homolog 2 | chr13 | GO:0060560 | Not Cancer Driver | No | 46 | 0.146 | 169 | 29 | 0.172 | 1 |
| STK11 | STK11 | Q15831 | Serine/threonine-protein kinase STK11 | chr19 | GO:0060560 | Census, Compendium | Yes | 75 | 0.173 | 135 | 14 | 0.104 | 9 |
| TBX2 | TBX2 | Q13207 | T-box transcription factor TBX2 | chr17 | GO:0060560 | Not Cancer Driver | No | 74 | 0.104 | 401 | 36 | 0.09 | 1 |
| TGFBR2_ENST00000295754 | TGFBR2 | P37173 | TGF-beta receptor type-2 | chr3 | GO:0060560 | Census, Compendium | Yes | 106 | 0.187 | 60 | 16 | 0.267 | 25 |
| TMEM108 | TMEM108 | Q6UXF1 | Transmembrane protein 108 | chr3 | GO:0060560 | Not Cancer Driver | No | 101 | 0.176 | 458 | 89 | 0.194 | 0 |
| WASF1_ENST00000392586 | WASF1 | Q92558 | Wiskott-Aldrich syndrome protein family member 1 | chr6 | GO:0060560 | Not Cancer Driver | No | 63 | 0.113 | 445 | 49 | 0.11 | 0 |
| WNT3A | WNT3A | P56704 | Protein Wnt-3a | chr1 | GO:0060560 | Not Cancer Driver | No | 77 | 0.219 | 37 | 5 | 0.135 | 0 |
| WNT7B | WNT7B | P56706 | Protein Wnt-7b | chr22 | GO:0060560 | Not Cancer Driver | No | 55 | 0.158 | 11 | 1 | 0.091 | 0 |
| YAP1_ENST00000282441 | YAP1 | P46937 | Transcriptional coactivator YAP1 | chr11 | GO:0060560 | Not Cancer Driver | No | 51 | 0.101 | 489 | 49 | 0.1 | 0 |