Total number of protein in "GO:0060537" GO term: 63
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADAMTS9 | ADAMTS9 | Q9P2N4 | A disintegrin and metalloproteinase with thrombospondin motifs 9 | chr3 | GO:0060537 | Not Cancer Driver | No | 288 | 0.149 | 235 | 38 | 0.162 | 0 |
| BMP4 | BMP4 | P12644 | Bone morphogenetic protein 4 | chr14 | GO:0060537 | Not Cancer Driver | No | 86 | 0.211 | 142 | 26 | 0.183 | 5 |
| BMPR1A | BMPR1A | P36894 | Bone morphogenetic protein receptor type-1A | chr10 | GO:0060537 | Census, Compendium | Yes | 66 | 0.124 | 21 | 0 | 0.0 | 8 |
| CACNA1G | CACNA1G | O43497 | Voltage-dependent T-type calcium channel subunit alpha-1G | chr17 | GO:0060537 | Not Cancer Driver | No | 367 | 0.154 | 1022 | 149 | 0.146 | 3 |
| CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | GO:0060537 | Not Cancer Driver | No | 39 | 0.204 | 23 | 2 | 0.087 | 1 |
| CSRP1_ENST00000340006 | CSRP1 | P21291 | Cysteine and glycine-rich protein 1 | chr1 | GO:0060537 | Not Cancer Driver | No | 18 | 0.093 | 28 | 4 | 0.143 | 0 |
| CSRP2 | CSRP2 | Q16527 | Cysteine and glycine-rich protein 2 | chr12 | GO:0060537 | Not Cancer Driver | No | 24 | 0.124 | 29 | 2 | 0.069 | 0 |
| CSRP3 | CSRP3 | P50461 | Cysteine and glycine-rich protein 3 | chr11 | GO:0060537 | Not Cancer Driver | No | 25 | 0.129 | 31 | 1 | 0.032 | 2 |
| DLG1_ENST00000419354 | DLG1 | Q12959 | Disks large homolog 1 | chr3 | GO:0060537 | Not Cancer Driver | No | 120 | 0.133 | 460 | 67 | 0.146 | 0 |
| DSG2 | DSG2 | Q14126 | Desmoglein-2 | chr18 | GO:0060537 | Not Cancer Driver | No | 173 | 0.155 | 476 | 68 | 0.143 | 5 |
| EDNRA | EDNRA | P25101 | Endothelin-1 receptor | chr4 | GO:0060537 | Not Cancer Driver | No | 62 | 0.145 | 21 | 6 | 0.286 | 2 |
| ENG | ENG | P17813 | Endoglin | chr9 | GO:0060537 | Not Cancer Driver | No | 60 | 0.091 | 114 | 15 | 0.132 | 32 |
| FOXL2 | FOXL2 | P58012 | Forkhead box protein L2 | chr3 | GO:0060537 | Census, Compendium | Yes | 39 | 0.104 | 257 | 20 | 0.078 | 26 |
| GATA4_ENST00000335135 | GATA4 | P43694 | Transcription factor GATA-4 | chr8 | GO:0060537 | Not Cancer Driver | No | 48 | 0.109 | 301 | 34 | 0.113 | 18 |
| GATA6 | GATA6 | Q92908 | Transcription factor GATA-6 | chr18 | GO:0060537 | Not Cancer Driver | No | 57 | 0.096 | 476 | 51 | 0.107 | 10 |
| GJA1 | GJA1 | P17302 | Gap junction alpha-1 protein | chr6 | GO:0060537 | Not Cancer Driver | No | 86 | 0.225 | 110 | 26 | 0.236 | 50 |
| GJA5 | GJA5 | P36382 | Gap junction alpha-5 protein | chr1 | GO:0060537 | Not Cancer Driver | No | 74 | 0.207 | 92 | 21 | 0.228 | 5 |
| GJB6_ENST00000644667 | GJB6 | O95452 | Gap junction beta-6 protein | chr13 | GO:0060537 | Not Cancer Driver | No | 42 | 0.161 | 12 | 4 | 0.333 | 4 |
| HCN4 | HCN4 | Q9Y3Q4 | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | chr15 | GO:0060537 | Not Cancer Driver | No | 187 | 0.155 | 631 | 58 | 0.092 | 3 |
| HEY1_ENST00000354724 | HEY1 | Q9Y5J3 | Hairy/enhancer-of-split related with YRPW motif protein 1 | chr8 | GO:0060537 | Census | Yes | 33 | 0.109 | 172 | 15 | 0.087 | 0 |
| HEY2 | HEY2 | Q9UBP5 | Hairy/enhancer-of-split related with YRPW motif protein 2 | chr6 | GO:0060537 | Not Cancer Driver | No | 64 | 0.19 | 179 | 26 | 0.145 | 0 |
| HOPX_ENST00000317745 | HOPX | Q9BPY8 | Homeodomain-only protein | chr4 | GO:0060537 | Not Cancer Driver | No | 13 | 0.178 | 48 | 10 | 0.208 | 0 |
| ID2_ENST00000396290 | ID2 | Q02363 | DNA-binding protein inhibitor ID-2 | chr2 | GO:0060537 | Not Cancer Driver | No | 14 | 0.104 | 52 | 7 | 0.135 | 0 |
| IHH | IHH | Q14623 | Indian hedgehog protein | chr2 | GO:0060537 | Not Cancer Driver | No | 58 | 0.141 | 111 | 15 | 0.135 | 6 |
| IRX3 | IRX3 | P78415 | Iroquois-class homeodomain protein IRX-3 | chr16 | GO:0060537 | Not Cancer Driver | No | 38 | 0.076 | 407 | 32 | 0.079 | 0 |
| ITGA8 | ITGA8 | P53708 | Integrin alpha-8 | chr10 | GO:0060537 | Not Cancer Driver | No | 292 | 0.275 | 114 | 26 | 0.228 | 1 |
| MAML1 | MAML1 | Q92585 | Mastermind-like protein 1 | chr5 | GO:0060537 | Not Cancer Driver | No | 102 | 0.1 | 1009 | 102 | 0.101 | 0 |
| MSC | MSC | O60682 | Musculin | chr8 | GO:0060537 | Not Cancer Driver | No | 47 | 0.228 | 173 | 41 | 0.237 | 0 |
| MSX1 | MSX1 | P28360 | Homeobox protein MSX-1 | chr4 | GO:0060537 | Not Cancer Driver | No | 39 | 0.129 | 197 | 16 | 0.081 | 7 |
| MSX2 | MSX2 | P35548 | Homeobox protein MSX-2 | chr5 | GO:0060537 | Not Cancer Driver | No | 27 | 0.101 | 168 | 14 | 0.083 | 4 |
| NF1 | NF1 | P21359 | Neurofibromin | chr17 | GO:0060537 | Census, Compendium | Yes | 375 | 0.132 | 406 | 47 | 0.116 | 85 |
| NKX2-5 | NKX2-5 | P52952 | Homeobox protein Nkx-2.5 | chr5 | GO:0060537 | Not Cancer Driver | No | 48 | 0.148 | 181 | 22 | 0.122 | 55 |
| NOTCH1 | NOTCH1 | P46531 | Neurogenic locus notch homolog protein 1 | chr9 | GO:0060537 | Census, Compendium | Yes | 363 | 0.142 | 686 | 87 | 0.127 | 3 |
| NOTCH2 | NOTCH2 | Q04721 | Neurogenic locus notch homolog protein 2 | chr1 | GO:0060537 | Census, Compendium | Yes | 282 | 0.114 | 630 | 77 | 0.122 | 1 |
| NPPA | NPPA | P01160 | Natriuretic peptides A | chr1 | GO:0060537 | Not Cancer Driver | No | 32 | 0.212 | 71 | 14 | 0.197 | 1 |
| NPPB | NPPB | P16860 | Natriuretic peptides B | chr1 | GO:0060537 | Not Cancer Driver | No | 31 | 0.231 | 104 | 28 | 0.269 | 0 |
| NRG1_ENST00000405005 | NRG1 | Q02297 | Pro-neuregulin-1, membrane-bound isoform | chr8 | GO:0060537 | Census, Compendium | Yes | 159 | 0.248 | 528 | 132 | 0.25 | 0 |
| OSR1 | OSR1 | Q8TAX0 | Protein odd-skipped-related 1 | chr2 | GO:0060537 | Not Cancer Driver | No | 57 | 0.214 | 67 | 17 | 0.254 | 0 |
| PITX1_ENST00000506438 | PITX1 | P78337 | Pituitary homeobox 1 | chr5 | GO:0060537 | Not Cancer Driver | No | 37 | 0.118 | 191 | 20 | 0.105 | 1 |
| PKD2 | PKD2 | Q13563 | Polycystin-2 | chr4 | GO:0060537 | Not Cancer Driver | No | 113 | 0.117 | 375 | 35 | 0.093 | 10 |
| POGLUT1 | POGLUT1 | Q8NBL1 | Protein O-glucosyltransferase 1 | chr3 | GO:0060537 | Not Cancer Driver | No | 57 | 0.145 | 0 | 0 | 0.0 | 3 |
| PPP1R13L_ENST00000360957 | PPP1R13L | Q8WUF5 | RelA-associated inhibitor | chr19 | GO:0060537 | Not Cancer Driver | No | 117 | 0.141 | 657 | 90 | 0.137 | 0 |
| PTCH1 | PTCH1 | Q13635 | Protein patched homolog 1 | chr9 | GO:0060537 | Census, Compendium | Yes | 243 | 0.168 | 382 | 67 | 0.175 | 18 |
| SCN5A_ENST00000333535 | SCN5A | Q14524 | Sodium channel protein type 5 subunit alpha | chr3 | GO:0060537 | Not Cancer Driver | No | 491 | 0.244 | 550 | 144 | 0.262 | 190 |
| SEMA3C | SEMA3C | Q99985 | Semaphorin-3C | chr7 | GO:0060537 | Not Cancer Driver | No | 136 | 0.181 | 111 | 23 | 0.207 | 0 |
| SHH | SHH | Q15465 | Sonic hedgehog protein | chr7 | GO:0060537 | Not Cancer Driver | No | 56 | 0.121 | 139 | 14 | 0.101 | 81 |
| SHOX2_ENST00000441443 | SHOX2 | O60902 | Short stature homeobox protein 2 | chr3 | GO:0060537 | Not Cancer Driver | No | 67 | 0.202 | 200 | 40 | 0.2 | 0 |
| SMAD1 | SMAD1 | Q15797 | Mothers against decapentaplegic homolog 1 | chr4 | GO:0060537 | Not Cancer Driver | No | 54 | 0.116 | 161 | 22 | 0.137 | 0 |
| SMAD4_ENST00000398417 | SMAD4 | Q13485 | Mothers against decapentaplegic homolog 4 | chr18 | GO:0060537 | Census, Compendium | Yes | 198 | 0.359 | 195 | 17 | 0.087 | 8 |
| SMAD5_ENST00000509297 | SMAD5 | Q99717 | Mothers against decapentaplegic homolog 5 | chr5 | GO:0060537 | Not Cancer Driver | No | 44 | 0.095 | 172 | 11 | 0.064 | 0 |
| SMO | SMO | Q99835 | Smoothened homolog | chr7 | GO:0060537 | Census, Compendium | Yes | 112 | 0.142 | 241 | 27 | 0.112 | 1 |
| SOX9 | SOX9 | P48436 | Transcription factor SOX-9 | chr17 | GO:0060537 | Compendium | Yes | 86 | 0.169 | 495 | 82 | 0.166 | 18 |
| SRF | SRF | P11831 | Serum response factor | chr6 | GO:0060537 | Not Cancer Driver | No | 44 | 0.087 | 443 | 42 | 0.095 | 0 |
| SRPK3 | SRPK3 | Q9UPE1 | SRSF protein kinase 3 | chrX | GO:0060537 | Not Cancer Driver | No | 63 | 0.111 | 217 | 30 | 0.138 | 0 |
| STRA6_ENST00000323940 | STRA6 | Q9BX79 | Receptor for retinol uptake STRA6 | chr15 | GO:0060537 | Not Cancer Driver | No | 77 | 0.115 | 84 | 14 | 0.167 | 6 |
| TBX18 | TBX18 | O95935 | T-box transcription factor TBX18 | chr6 | GO:0060537 | Not Cancer Driver | No | 156 | 0.257 | 356 | 94 | 0.264 | 2 |
| TBX5 | TBX5 | Q99593 | T-box transcription factor TBX5 | chr12 | GO:0060537 | Not Cancer Driver | No | 155 | 0.299 | 351 | 113 | 0.322 | 5 |
| TCF21 | TCF21 | O43680 | Transcription factor 21 | chr6 | GO:0060537 | Not Cancer Driver | No | 55 | 0.307 | 120 | 40 | 0.333 | 0 |
| TFAP2B | TFAP2B | Q92481 | Transcription factor AP-2-beta | chr6 | GO:0060537 | Not Cancer Driver | No | 114 | 0.248 | 306 | 75 | 0.245 | 6 |
| TIPARP | TIPARP | Q7Z3E1 | Protein mono-ADP-ribosyltransferase TIPARP | chr3 | GO:0060537 | Not Cancer Driver | No | 65 | 0.099 | 200 | 20 | 0.1 | 0 |
| TREX1_ENST00000625293 | TREX1 | Q9NSU2 | Three-prime repair exonuclease 1 | chr3 | GO:0060537 | Not Cancer Driver | No | 26 | 0.083 | 98 | 10 | 0.102 | 18 |
| ZFAND5 | ZFAND5 | O76080 | AN1-type zinc finger protein 5 | chr9 | GO:0060537 | Not Cancer Driver | No | 31 | 0.146 | 162 | 19 | 0.117 | 0 |
| ZMPSTE24 | ZMPSTE24 | O75844 | CAAX prenyl protease 1 homolog | chr1 | GO:0060537 | Not Cancer Driver | No | 67 | 0.141 | 23 | 0 | 0.0 | 3 |