Total number of protein in "GO:0060070" GO term: 75
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AXIN1 | AXIN1 | O15169 | Axin-1 | chr16 | GO:0060070 | Census, Compendium | Yes | 120 | 0.139 | 619 | 88 | 0.142 | 4 |
| BCL9 | BCL9 | O00512 | B-cell CLL/lymphoma 9 protein | chr1 | GO:0060070 | Census, Compendium | Yes | 219 | 0.154 | 1426 | 219 | 0.154 | 0 |
| BCL9L | BCL9L | Q86UU0 | B-cell CLL/lymphoma 9-like protein | chr11 | GO:0060070 | Census, Compendium | Yes | 200 | 0.133 | 1495 | 200 | 0.134 | 0 |
| CDH3 | CDH3 | P22223 | Cadherin-3 | chr16 | GO:0060070 | Not Cancer Driver | No | 87 | 0.105 | 488 | 52 | 0.107 | 2 |
| CSNK1E | CSNK1E | P49674 | Casein kinase I isoform epsilon | chr22 | GO:0060070 | Not Cancer Driver | No | 62 | 0.149 | 133 | 18 | 0.135 | 0 |
| CTNNB1_ENST00000643977 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | GO:0060070 | Census, Compendium | Yes | 415 | 0.531 | 288 | 301 | 1.045 | 14 |
| DISC1_ENST00000439617 | DISC1 | Q9NRI5 | Disrupted in schizophrenia 1 protein | chr1 | GO:0060070 | Not Cancer Driver | No | 132 | 0.155 | 514 | 82 | 0.16 | 0 |
| DIXDC1 | DIXDC1 | Q155Q3 | Dixin | chr11 | GO:0060070 | Not Cancer Driver | No | 72 | 0.105 | 495 | 55 | 0.111 | 0 |
| DVL1 | DVL1 | O14640 | Segment polarity protein dishevelled homolog DVL-1 | chr1 | GO:0060070 | Not Cancer Driver | No | 73 | 0.105 | 434 | 38 | 0.088 | 0 |
| DVL2 | DVL2 | O14641 | Segment polarity protein dishevelled homolog DVL-2 | chr17 | GO:0060070 | Not Cancer Driver | No | 96 | 0.13 | 514 | 64 | 0.125 | 0 |
| DVL3 | DVL3 | Q92997 | Segment polarity protein dishevelled homolog DVL-3 | chr3 | GO:0060070 | Not Cancer Driver | No | 97 | 0.135 | 437 | 58 | 0.133 | 0 |
| EDN1 | EDN1 | P05305 | Endothelin-1 | chr6 | GO:0060070 | Not Cancer Driver | No | 37 | 0.175 | 97 | 20 | 0.206 | 3 |
| EDNRA | EDNRA | P25101 | Endothelin-1 receptor | chr4 | GO:0060070 | Not Cancer Driver | No | 62 | 0.145 | 21 | 6 | 0.286 | 2 |
| EDNRB_ENST00000334286 | EDNRB | P24530 | Endothelin receptor type B | chr13 | GO:0060070 | Not Cancer Driver | No | 112 | 0.253 | 56 | 19 | 0.339 | 6 |
| EXT1 | EXT1 | Q16394 | Exostosin-1 | chr8 | GO:0060070 | Census | Yes | 107 | 0.143 | 58 | 7 | 0.121 | 12 |
| FRAT1 | FRAT1 | Q92837 | Proto-oncogene FRAT1 | chr10 | GO:0060070 | Not Cancer Driver | No | 6 | 0.022 | 266 | 6 | 0.023 | 0 |
| FRZB | FRZB | Q92765 | Secreted frizzled-related protein 3 | chr2 | GO:0060070 | Not Cancer Driver | No | 58 | 0.178 | 31 | 6 | 0.194 | 1 |
| FZD1 | FZD1 | Q9UP38 | Frizzled-1 | chr7 | GO:0060070 | Not Cancer Driver | No | 78 | 0.121 | 133 | 2 | 0.015 | 0 |
| FZD10 | FZD10 | Q9ULW2 | Frizzled-10 | chr12 | GO:0060070 | Not Cancer Driver | No | 148 | 0.255 | 65 | 15 | 0.231 | 0 |
| FZD2 | FZD2 | Q14332 | Frizzled-2 | chr17 | GO:0060070 | Not Cancer Driver | No | 85 | 0.15 | 47 | 5 | 0.106 | 1 |
| FZD3_ENST00000240093 | FZD3 | Q9NPG1 | Frizzled-3 | chr8 | GO:0060070 | Not Cancer Driver | No | 64 | 0.096 | 141 | 13 | 0.092 | 0 |
| FZD4 | FZD4 | Q9ULV1 | Frizzled-4 | chr11 | GO:0060070 | Not Cancer Driver | No | 57 | 0.106 | 33 | 5 | 0.152 | 19 |
| FZD5 | FZD5 | Q13467 | Frizzled-5 | chr2 | GO:0060070 | Not Cancer Driver | No | 45 | 0.077 | 58 | 4 | 0.069 | 0 |
| FZD6 | FZD6 | O60353 | Frizzled-6 | chr8 | GO:0060070 | Not Cancer Driver | No | 95 | 0.135 | 172 | 15 | 0.087 | 1 |
| FZD7 | FZD7 | O75084 | Frizzled-7 | chr2 | GO:0060070 | Not Cancer Driver | No | 90 | 0.157 | 22 | 2 | 0.091 | 0 |
| FZD8 | FZD8 | Q9H461 | Frizzled-8 | chr10 | GO:0060070 | Not Cancer Driver | No | 72 | 0.104 | 146 | 3 | 0.021 | 0 |
| FZD9 | FZD9 | O00144 | Frizzled-9 | chr7 | GO:0060070 | Not Cancer Driver | No | 55 | 0.093 | 61 | 0 | 0.0 | 0 |
| GATA3_ENST00000346208 | GATA3 | P23771 | Trans-acting T-cell-specific transcription factor GATA-3 | chr10 | GO:0060070 | Census, Compendium | Yes | 111 | 0.251 | 364 | 87 | 0.239 | 2 |
| GLI1 | GLI1 | P08151 | Zinc finger protein GLI1 | chr12 | GO:0060070 | Census, Compendium | Yes | 206 | 0.186 | 1015 | 184 | 0.181 | 0 |
| HESX1 | HESX1 | Q9UBX0 | Homeobox expressed in ES cells 1 | chr3 | GO:0060070 | Not Cancer Driver | No | 32 | 0.173 | 59 | 9 | 0.153 | 6 |
| LEF1 | LEF1 | Q9UJU2 | Lymphoid enhancer-binding factor 1 | chr4 | GO:0060070 | Census | Yes | 64 | 0.16 | 370 | 57 | 0.154 | 0 |
| LGR4 | LGR4 | Q9BXB1 | Leucine-rich repeat-containing G-protein coupled receptor 4 | chr11 | GO:0060070 | Not Cancer Driver | No | 108 | 0.114 | 16 | 3 | 0.188 | 0 |
| LRP5 | LRP5 | O75197 | Low-density lipoprotein receptor-related protein 5 | chr11 | GO:0060070 | Not Cancer Driver | No | 253 | 0.157 | 188 | 28 | 0.149 | 55 |
| LRP6 | LRP6 | O75581 | Low-density lipoprotein receptor-related protein 6 | chr12 | GO:0060070 | Not Cancer Driver | No | 206 | 0.128 | 255 | 30 | 0.118 | 5 |
| LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | GO:0060070 | Not Cancer Driver | No | 519 | 0.205 | 90 | 17 | 0.189 | 23 |
| MED12 | MED12 | Q93074 | Mediator of RNA polymerase II transcription subunit 12 | chrX | GO:0060070 | Census, Compendium | Yes | 409 | 0.188 | 974 | 175 | 0.18 | 5 |
| MITF_ENST00000448226 | MITF | O75030 | Microphthalmia-associated transcription factor | chr3 | GO:0060070 | Census | Yes | 80 | 0.152 | 408 | 69 | 0.169 | 7 |
| NR4A2_ENST00000409572 | NR4A2 | P43354 | Nuclear receptor subfamily 4 group A member 2 | chr2 | GO:0060070 | Not Cancer Driver | No | 110 | 0.184 | 261 | 38 | 0.146 | 0 |
| PLPP3 | PLPP3 | O14495 | Phospholipid phosphatase 3 | chr1 | GO:0060070 | Not Cancer Driver | No | 48 | 0.154 | 10 | 1 | 0.1 | 0 |
| PORCN | PORCN | Q9H237 | Protein-serine O-palmitoleoyltransferase porcupine | chrX | GO:0060070 | Not Cancer Driver | No | 77 | 0.167 | 0 | 0 | 0.0 | 15 |
| PROP1 | PROP1 | O75360 | Homeobox protein prophet of Pit-1 | chr5 | GO:0060070 | Not Cancer Driver | No | 35 | 0.155 | 194 | 32 | 0.165 | 7 |
| PTEN | PTEN | P60484 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | chr10 | GO:0060070 | Census, Compendium | Yes | 505 | 1.253 | 76 | 4 | 0.053 | 41 |
| PYGO1 | PYGO1 | Q9Y3Y4 | Pygopus homolog 1 | chr15 | GO:0060070 | Not Cancer Driver | No | 71 | 0.169 | 362 | 60 | 0.166 | 0 |
| PYGO2 | PYGO2 | Q9BRQ0 | Pygopus homolog 2 | chr1 | GO:0060070 | Not Cancer Driver | No | 51 | 0.126 | 340 | 43 | 0.126 | 0 |
| RARG | RARG | P13631 | Retinoic acid receptor gamma | chr12 | GO:0060070 | Not Cancer Driver | No | 82 | 0.181 | 164 | 24 | 0.146 | 0 |
| RECK | RECK | O95980 | Reversion-inducing cysteine-rich protein with Kazal motifs | chr9 | GO:0060070 | Not Cancer Driver | No | 115 | 0.118 | 9 | 2 | 0.222 | 0 |
| RYK_ENST00000623711 | RYK | P34925 | Tyrosine-protein kinase RYK | chr3 | GO:0060070 | Not Cancer Driver | No | 55 | 0.091 | 85 | 4 | 0.047 | 0 |
| SDC1_ENST00000254351 | SDC1 | P18827 | Syndecan-1 | chr2 | GO:0060070 | Not Cancer Driver | No | 31 | 0.1 | 259 | 30 | 0.116 | 0 |
| SFRP1 | SFRP1 | Q8N474 | Secreted frizzled-related protein 1 | chr8 | GO:0060070 | Not Cancer Driver | No | 40 | 0.127 | 39 | 7 | 0.179 | 0 |
| SFRP2 | SFRP2 | Q96HF1 | Secreted frizzled-related protein 2 | chr4 | GO:0060070 | Not Cancer Driver | No | 47 | 0.159 | 1 | 0 | 0.0 | 0 |
| SFRP4 | SFRP4 | Q6FHJ7 | Secreted frizzled-related protein 4 | chr7 | GO:0060070 | Census | Yes | 81 | 0.234 | 68 | 22 | 0.324 | 0 |
| SFRP5 | SFRP5 | Q5T4F7 | Secreted frizzled-related protein 5 | chr10 | GO:0060070 | Not Cancer Driver | No | 26 | 0.082 | 7 | 3 | 0.429 | 0 |
| SHH | SHH | Q15465 | Sonic hedgehog protein | chr7 | GO:0060070 | Not Cancer Driver | No | 56 | 0.121 | 139 | 14 | 0.101 | 81 |
| STK11 | STK11 | Q15831 | Serine/threonine-protein kinase STK11 | chr19 | GO:0060070 | Census, Compendium | Yes | 75 | 0.173 | 135 | 14 | 0.104 | 9 |
| TCF7L1 | TCF7L1 | Q9HCS4 | Transcription factor 7-like 1 | chr2 | GO:0060070 | Not Cancer Driver | No | 54 | 0.092 | 552 | 51 | 0.092 | 0 |
| TCF7L2_ENST00000355995 | TCF7L2 | Q9NQB0 | Transcription factor 7-like 2 | chr10 | GO:0060070 | Census, Compendium | Yes | 122 | 0.197 | 516 | 93 | 0.18 | 0 |
| WNT1 | WNT1 | P04628 | Proto-oncogene Wnt-1 | chr12 | GO:0060070 | Not Cancer Driver | No | 29 | 0.078 | 25 | 0 | 0.0 | 8 |
| WNT10A | WNT10A | Q9GZT5 | Protein Wnt-10a | chr2 | GO:0060070 | Not Cancer Driver | No | 39 | 0.094 | 123 | 10 | 0.081 | 9 |
| WNT10B | WNT10B | O00744 | Protein Wnt-10b | chr12 | GO:0060070 | Not Cancer Driver | No | 56 | 0.144 | 84 | 16 | 0.19 | 2 |
| WNT11 | WNT11 | O96014 | Protein Wnt-11 | chr11 | GO:0060070 | Not Cancer Driver | No | 55 | 0.155 | 59 | 4 | 0.068 | 0 |
| WNT16 | WNT16 | Q9UBV4 | Protein Wnt-16 | chr7 | GO:0060070 | Not Cancer Driver | No | 59 | 0.162 | 28 | 9 | 0.321 | 0 |
| WNT2 | WNT2 | P09544 | Protein Wnt-2 | chr7 | GO:0060070 | Not Cancer Driver | No | 85 | 0.236 | 11 | 3 | 0.273 | 0 |
| WNT2B | WNT2B | Q93097 | Protein Wnt-2b | chr1 | GO:0060070 | Not Cancer Driver | No | 72 | 0.184 | 27 | 3 | 0.111 | 0 |
| WNT3 | WNT3 | P56703 | Proto-oncogene Wnt-3 | chr17 | GO:0060070 | Not Cancer Driver | No | 56 | 0.158 | 34 | 7 | 0.206 | 0 |
| WNT3A | WNT3A | P56704 | Protein Wnt-3a | chr1 | GO:0060070 | Not Cancer Driver | No | 77 | 0.219 | 37 | 5 | 0.135 | 0 |
| WNT4 | WNT4 | P56705 | Protein Wnt-4 | chr1 | GO:0060070 | Not Cancer Driver | No | 30 | 0.085 | 39 | 4 | 0.103 | 4 |
| WNT5A_ENST00000474267 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:0060070 | Not Cancer Driver | No | 66 | 0.174 | 0 | 0 | 0.0 | 2 |
| WNT5B_ENST00000310594 | WNT5B | Q9H1J7 | Protein Wnt-5b | chr12 | GO:0060070 | Not Cancer Driver | No | 60 | 0.167 | 23 | 4 | 0.174 | 0 |
| WNT6 | WNT6 | Q9Y6F9 | Protein Wnt-6 | chr2 | GO:0060070 | Not Cancer Driver | No | 30 | 0.082 | 84 | 9 | 0.107 | 0 |
| WNT7A | WNT7A | O00755 | Protein Wnt-7a | chr3 | GO:0060070 | Not Cancer Driver | No | 93 | 0.266 | 18 | 9 | 0.5 | 4 |
| WNT7B | WNT7B | P56706 | Protein Wnt-7b | chr22 | GO:0060070 | Not Cancer Driver | No | 55 | 0.158 | 11 | 1 | 0.091 | 0 |
| WNT8A_ENST00000398754 | WNT8A | Q9H1J5 | Protein Wnt-8a | chr5 | GO:0060070 | Not Cancer Driver | No | 50 | 0.142 | 3 | 0 | 0.0 | 0 |
| WNT8B | WNT8B | Q93098 | Protein Wnt-8b | chr10 | GO:0060070 | Not Cancer Driver | No | 50 | 0.142 | 27 | 5 | 0.185 | 0 |
| WNT9A | WNT9A | O14904 | Protein Wnt-9a | chr1 | GO:0060070 | Not Cancer Driver | No | 74 | 0.203 | 44 | 11 | 0.25 | 0 |
| WNT9B | WNT9B | O14905 | Protein Wnt-9b | chr17 | GO:0060070 | Not Cancer Driver | No | 47 | 0.132 | 11 | 4 | 0.364 | 0 |