Total number of protein in "GO:0055088" GO term: 82
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABCA1 | ABCA1 | O95477 | Phospholipid-transporting ATPase ABCA1 | chr9 | GO:0055088 | Not Cancer Driver | No | 284 | 0.126 | 245 | 40 | 0.163 | 31 |
| ABCA12 | ABCA12 | Q86UK0 | Glucosylceramide transporter ABCA12 | chr2 | GO:0055088 | Not Cancer Driver | No | 511 | 0.197 | 136 | 23 | 0.169 | 14 |
| ABCA2_ENST00000371605 | ABCA2 | Q9BZC7 | ATP-binding cassette sub-family A member 2 | chr9 | GO:0055088 | Not Cancer Driver | No | 240 | 0.099 | 497 | 44 | 0.089 | 0 |
| ABCA3 | ABCA3 | Q99758 | Phospholipid-transporting ATPase ABCA3 | chr16 | GO:0055088 | Not Cancer Driver | No | 224 | 0.131 | 77 | 4 | 0.052 | 13 |
| ABCB11 | ABCB11 | O95342 | Bile salt export pump | chr2 | GO:0055088 | Not Cancer Driver | No | 233 | 0.176 | 124 | 24 | 0.194 | 21 |
| ABCB4 | ABCB4 | P21439 | Phosphatidylcholine translocator ABCB4 | chr7 | GO:0055088 | Not Cancer Driver | No | 243 | 0.189 | 74 | 14 | 0.189 | 72 |
| ABCD1 | ABCD1 | P33897 | ATP-binding cassette sub-family D member 1 | chrX | GO:0055088 | Not Cancer Driver | No | 106 | 0.142 | 75 | 5 | 0.067 | 138 |
| ABCG1 | ABCG1 | P45844 | ATP-binding cassette sub-family G member 1 | chr21 | GO:0055088 | Not Cancer Driver | No | 104 | 0.153 | 32 | 5 | 0.156 | 0 |
| ABHD4 | ABHD4 | Q8TB40 | (Lyso)-N-acylphosphatidylethanolamine lipase | chr14 | GO:0055088 | Not Cancer Driver | No | 46 | 0.135 | 39 | 5 | 0.128 | 0 |
| ABHD5 | ABHD5 | Q8WTS1 | 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 | chr3 | GO:0055088 | Not Cancer Driver | No | 34 | 0.097 | 18 | 1 | 0.056 | 4 |
| ABHD8 | ABHD8 | Q96I13 | Protein ABHD8 | chr19 | GO:0055088 | Not Cancer Driver | No | 58 | 0.132 | 134 | 19 | 0.142 | 0 |
| ACOX1_ENST00000301608 | ACOX1 | Q15067 | Peroxisomal acyl-coenzyme A oxidase 1 | chr17 | GO:0055088 | Not Cancer Driver | No | 71 | 0.108 | 63 | 11 | 0.175 | 7 |
| ACOX2 | ACOX2 | Q99424 | Peroxisomal acyl-coenzyme A oxidase 2 | chr3 | GO:0055088 | Not Cancer Driver | No | 79 | 0.116 | 35 | 9 | 0.257 | 1 |
| ACOX3 | ACOX3 | O15254 | Peroxisomal acyl-coenzyme A oxidase 3 | chr4 | GO:0055088 | Not Cancer Driver | No | 107 | 0.153 | 26 | 6 | 0.231 | 0 |
| ACOXL_ENST00000389811 | ACOXL | Q9NUZ1 | Acyl-coenzyme A oxidase-like protein | chr2 | GO:0055088 | Not Cancer Driver | No | 96 | 0.176 | 21 | 4 | 0.19 | 0 |
| ADCK1 | ADCK1 | Q86TW2 | AarF domain-containing protein kinase 1 | chr14 | GO:0055088 | Not Cancer Driver | No | 82 | 0.155 | 6 | 3 | 0.5 | 0 |
| ADORA1 | ADORA1 | P30542 | Adenosine receptor A1 | chr1 | GO:0055088 | Not Cancer Driver | No | 64 | 0.196 | 12 | 4 | 0.333 | 0 |
| ANGPTL3 | ANGPTL3 | Q9Y5C1 | Angiopoietin-related protein 3 | chr1 | GO:0055088 | Not Cancer Driver | No | 52 | 0.113 | 154 | 26 | 0.169 | 0 |
| APOA1_ENST00000375320 | APOA1 | P02647 | Apolipoprotein A-I | chr11 | GO:0055088 | Not Cancer Driver | No | 28 | 0.105 | 131 | 8 | 0.061 | 3 |
| APOA4 | APOA4 | P06727 | Apolipoprotein A-IV | chr11 | GO:0055088 | Not Cancer Driver | No | 77 | 0.194 | 298 | 65 | 0.218 | 0 |
| APOA5 | APOA5 | Q6Q788 | Apolipoprotein A-V | chr11 | GO:0055088 | Not Cancer Driver | No | 51 | 0.139 | 178 | 26 | 0.146 | 0 |
| APOE | APOE | P02649 | Apolipoprotein E | chr19 | GO:0055088 | Not Cancer Driver | No | 25 | 0.079 | 124 | 6 | 0.048 | 12 |
| ATP13A2 | ATP13A2 | Q9NQ11 | Polyamine-transporting ATPase 13A2 | chr1 | GO:0055088 | Not Cancer Driver | No | 152 | 0.129 | 121 | 10 | 0.083 | 9 |
| BLOC1S6_ENST00000220531 | BLOC1S6 | Q9UL45 | Biogenesis of lysosome-related organelles complex 1 subunit 6 | chr15 | GO:0055088 | Not Cancer Driver | No | 12 | 0.07 | 111 | 11 | 0.099 | 0 |
| C1QTNF3_ENST00000231338 | C1QTNF3 | Q9BXJ4 | Complement C1q tumor necrosis factor-related protein 3 | chr5 | GO:0055088 | Not Cancer Driver | No | 42 | 0.171 | 73 | 14 | 0.192 | 0 |
| CEBPA | CEBPA | P49715 | CCAAT/enhancer-binding protein alpha | chr19 | GO:0055088 | Census, Compendium | Yes | 12 | 0.034 | 342 | 12 | 0.035 | 1 |
| CETP | CETP | P11597 | Cholesteryl ester transfer protein | chr16 | GO:0055088 | Not Cancer Driver | No | 58 | 0.118 | 0 | 0 | 0.0 | 3 |
| CLN8 | CLN8 | Q9UBY8 | Protein CLN8 | chr8 | GO:0055088 | Not Cancer Driver | No | 45 | 0.157 | 16 | 2 | 0.125 | 16 |
| COL4A3BP_ENST00000261415 | CERT1 | Q9Y5P4 | Ceramide transfer protein | chr5 | GO:0055088 | Not Cancer Driver | No | 73 | 0.117 | 215 | 23 | 0.107 | 2 |
| DDX3X_ENST00000629496 | DDX3X | O00571 | ATP-dependent RNA helicase DDX3X | chrX | GO:0055088 | Census, Compendium | Yes | 133 | 0.201 | 301 | 47 | 0.156 | 18 |
| DGAT1 | DGAT1 | O75907 | Diacylglycerol O-acyltransferase 1 | chr8 | GO:0055088 | Not Cancer Driver | No | 52 | 0.107 | 62 | 0 | 0.0 | 0 |
| DGAT2 | DGAT2 | Q96PD7 | Diacylglycerol O-acyltransferase 2 | chr11 | GO:0055088 | Not Cancer Driver | No | 56 | 0.144 | 17 | 2 | 0.118 | 0 |
| ENPP7 | ENPP7 | Q6UWV6 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 | chr17 | GO:0055088 | Not Cancer Driver | No | 102 | 0.223 | 65 | 19 | 0.292 | 0 |
| FABP3 | FABP3 | P05413 | Fatty acid-binding protein, heart | chr1 | GO:0055088 | Not Cancer Driver | No | 22 | 0.165 | 3 | 0 | 0.0 | 0 |
| FAM57A | TLCD3A | Q8TBR7 | TLC domain-containing protein 3A | chr17 | GO:0055088 | Not Cancer Driver | No | 21 | 0.082 | 0 | 0 | 0.0 | 0 |
| FAM57B | TLCD3B | Q71RH2 | Ceramide synthase | chr16 | GO:0055088 | Not Cancer Driver | No | 40 | 0.146 | 6 | 3 | 0.5 | 0 |
| FBXW7_ENST00000603841 | FBXW7 | Q969H0 | F-box/WD repeat-containing protein 7 | chr4 | GO:0055088 | Census, Compendium | Yes | 322 | 0.455 | 230 | 38 | 0.165 | 0 |
| FITM2 | FITM2 | Q8N6M3 | Acyl-coenzyme A diphosphatase FITM2 | chr20 | GO:0055088 | Not Cancer Driver | No | 28 | 0.107 | 0 | 0 | 0.0 | 1 |
| FUNDC2 | FUNDC2 | Q9BWH2 | FUN14 domain-containing protein 2 | chrX | GO:0055088 | Not Cancer Driver | No | 28 | 0.148 | 34 | 3 | 0.088 | 0 |
| GOT1 | GOT1 | P17174 | Aspartate aminotransferase, cytoplasmic | chr10 | GO:0055088 | Not Cancer Driver | No | 56 | 0.136 | 35 | 5 | 0.143 | 0 |
| GPAM | GPAM | Q9HCL2 | Glycerol-3-phosphate acyltransferase 1, mitochondrial | chr10 | GO:0055088 | Not Cancer Driver | No | 108 | 0.13 | 83 | 7 | 0.084 | 0 |
| HNF4A | HNF4A | P41235 | Hepatocyte nuclear factor 4-alpha | chr20 | GO:0055088 | Not Cancer Driver | No | 135 | 0.285 | 127 | 48 | 0.378 | 5 |
| HPS6 | HPS6 | Q86YV9 | Hermansky-Pudlak syndrome 6 protein | chr10 | GO:0055088 | Not Cancer Driver | No | 77 | 0.099 | 145 | 20 | 0.138 | 0 |
| INS | INS | P01308 | Insulin | chr11 | GO:0055088 | Not Cancer Driver | No | 15 | 0.136 | 5 | 1 | 0.2 | 22 |
| IRS2 | IRS2 | Q9Y4H2 | Insulin receptor substrate 2 | chr13 | GO:0055088 | Not Cancer Driver | No | 69 | 0.052 | 1112 | 57 | 0.051 | 0 |
| ITGB6_ENST00000409872 | ITGB6 | P18564 | Integrin beta-6 | chr2 | GO:0055088 | Not Cancer Driver | No | 120 | 0.152 | 26 | 4 | 0.154 | 3 |
| LIPG | LIPG | Q9Y5X9 | Endothelial lipase | chr18 | GO:0055088 | Not Cancer Driver | No | 90 | 0.18 | 59 | 7 | 0.119 | 0 |
| MLXIPL | MLXIPL | Q9NP71 | Carbohydrate-responsive element-binding protein | chr7 | GO:0055088 | Not Cancer Driver | No | 106 | 0.124 | 554 | 66 | 0.119 | 0 |
| MTCH2 | MTCH2 | Q9Y6C9 | Mitochondrial carrier homolog 2 | chr11 | GO:0055088 | Not Cancer Driver | No | 45 | 0.149 | 11 | 0 | 0.0 | 0 |
| NR1D2 | NR1D2 | Q14995 | Nuclear receptor subfamily 1 group D member 2 | chr3 | GO:0055088 | Not Cancer Driver | No | 76 | 0.131 | 223 | 25 | 0.112 | 0 |
| NR1H3_ENST00000467728 | NR1H3 | Q13133 | Oxysterols receptor LXR-alpha | chr11 | GO:0055088 | Not Cancer Driver | No | 56 | 0.125 | 146 | 13 | 0.089 | 0 |
| NR1H4 | NR1H4 | Q96RI1 | Bile acid receptor | chr12 | GO:0055088 | Not Cancer Driver | No | 111 | 0.228 | 78 | 18 | 0.231 | 0 |
| OR10J5 | OR10J5 | Q8NHC4 | Olfactory receptor 10J5 | chr1 | GO:0055088 | Not Cancer Driver | No | 95 | 0.307 | 0 | 0 | 0.0 | 0 |
| ORMDL1_ENST00000392350 | ORMDL1 | Q9P0S3 | ORM1-like protein 1 | chr2 | GO:0055088 | Not Cancer Driver | No | 12 | 0.078 | 0 | 0 | 0.0 | 0 |
| ORMDL2_ENST00000548974 | ORMDL2 | Q53FV1 | ORM1-like protein 2 | chr12 | GO:0055088 | Not Cancer Driver | No | 10 | 0.065 | 0 | 0 | 0.0 | 0 |
| ORMDL3_ENST00000304046 | ORMDL3 | Q8N138 | ORM1-like protein 3 | chr17 | GO:0055088 | Not Cancer Driver | No | 22 | 0.144 | 9 | 1 | 0.111 | 0 |
| PNPLA1 | PNPLA1 | Q8N8W4 | Omega-hydroxyceramide transacylase | chr6 | GO:0055088 | Not Cancer Driver | No | 89 | 0.167 | 253 | 48 | 0.19 | 2 |
| PNPLA2 | PNPLA2 | Q96AD5 | Patatin-like phospholipase domain-containing protein 2 | chr11 | GO:0055088 | Not Cancer Driver | No | 35 | 0.069 | 101 | 4 | 0.04 | 1 |
| PNPLA3 | PNPLA3 | Q9NST1 | 1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 | chr22 | GO:0055088 | Not Cancer Driver | No | 54 | 0.112 | 33 | 7 | 0.212 | 0 |
| PNPLA4_ENST00000444736 | PNPLA4 | P41247 | Patatin-like phospholipase domain-containing protein 4 | chrX | GO:0055088 | Not Cancer Driver | No | 41 | 0.162 | 3 | 0 | 0.0 | 0 |
| PNPLA5 | PNPLA5 | Q7Z6Z6 | Patatin-like phospholipase domain-containing protein 5 | chr22 | GO:0055088 | Not Cancer Driver | No | 78 | 0.182 | 33 | 8 | 0.242 | 0 |
| PNPLA8 | PNPLA8 | Q9NP80 | Calcium-independent phospholipase A2-gamma | chr7 | GO:0055088 | Not Cancer Driver | No | 94 | 0.12 | 140 | 18 | 0.129 | 0 |
| POLD1_ENST00000440232 | POLD1 | P28340 | DNA polymerase delta catalytic subunit | chr19 | GO:0055088 | Census, Compendium | Yes | 179 | 0.162 | 214 | 31 | 0.145 | 2 |
| PPARG | PPARG | P37231 | Peroxisome proliferator-activated receptor gamma | chr3 | GO:0055088 | Census | Yes | 72 | 0.143 | 44 | 4 | 0.091 | 3 |
| PRKAA1_ENST00000397128 | PRKAA1 | Q13131 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | chr5 | GO:0055088 | Not Cancer Driver | No | 72 | 0.129 | 124 | 17 | 0.137 | 0 |
| PRKAA2 | PRKAA2 | P54646 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | chr1 | GO:0055088 | Not Cancer Driver | No | 128 | 0.232 | 98 | 26 | 0.265 | 0 |
| RBP1_ENST00000619087 | RBP1 | P09455 | Retinol-binding protein 1 | chr3 | GO:0055088 | Not Cancer Driver | No | 24 | 0.178 | 0 | 0 | 0.0 | 0 |
| RCN3 | RCN3 | Q96D15 | Reticulocalbin-3 | chr19 | GO:0055088 | Not Cancer Driver | No | 44 | 0.134 | 243 | 39 | 0.16 | 0 |
| RTN4 | RTN4 | Q9NQC3 | Reticulon-4 | chr2 | GO:0055088 | Not Cancer Driver | No | 121 | 0.102 | 866 | 82 | 0.095 | 0 |
| SAR1B | SAR1B | Q9Y6B6 | GTP-binding protein SAR1b | chr5 | GO:0055088 | Not Cancer Driver | No | 17 | 0.086 | 4 | 0 | 0.0 | 5 |
| SIRT1 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | GO:0055088 | Not Cancer Driver | No | 70 | 0.094 | 435 | 31 | 0.071 | 0 |
| SURF4 | SURF4 | O15260 | Surfeit locus protein 4 | chr9 | GO:0055088 | Not Cancer Driver | No | 29 | 0.108 | 0 | 0 | 0.0 | 0 |
| THADA_ENST00000405975 | THADA | Q6YHU6 | Thyroid adenoma-associated protein | chr2 | GO:0055088 | Not Cancer Driver | No | 204 | 0.104 | 63 | 6 | 0.095 | 0 |
| TLCD1 | TLCD1 | Q96CP7 | TLC domain-containing protein 1 | chr17 | GO:0055088 | Not Cancer Driver | No | 30 | 0.121 | 0 | 0 | 0.0 | 0 |
| TLCD2 | TLCD2 | A6NGC4 | TLC domain-containing protein 2 | chr17 | GO:0055088 | Not Cancer Driver | No | 1 | 0.004 | 35 | 1 | 0.029 | 0 |
| TM6SF2 | TM6SF2 | Q9BZW4 | Transmembrane 6 superfamily member 2 | chr19 | GO:0055088 | Not Cancer Driver | No | 53 | 0.141 | 3 | 0 | 0.0 | 0 |
| TMEM56 | TLCD4 | Q96MV1 | TLC domain-containing protein 4 | chr1 | GO:0055088 | Not Cancer Driver | No | 32 | 0.122 | 0 | 0 | 0.0 | 0 |
| TREM2 | TREM2 | Q9NZC2 | Triggering receptor expressed on myeloid cells 2 | chr6 | GO:0055088 | Not Cancer Driver | No | 43 | 0.187 | 27 | 2 | 0.074 | 1 |
| USF1 | USF1 | P22415 | Upstream stimulatory factor 1 | chr1 | GO:0055088 | Not Cancer Driver | No | 52 | 0.168 | 271 | 44 | 0.162 | 0 |
| USF2 | USF2 | Q15853 | Upstream stimulatory factor 2 | chr19 | GO:0055088 | Not Cancer Driver | No | 30 | 0.087 | 326 | 29 | 0.089 | 0 |
| XBP1 | XBP1 | P17861 | X-box-binding protein 1 | chr22 | GO:0055088 | Not Cancer Driver | No | 19 | 0.073 | 169 | 9 | 0.053 | 0 |
| ZBTB20 | ZBTB20 | Q9HC78 | Zinc finger and BTB domain-containing protein 20 | chr3 | GO:0055088 | Compendium | Yes | 151 | 0.204 | 433 | 80 | 0.185 | 4 |