Total number of protein in "GO:0055067" GO term: 94
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGT | AGT | P01019 | Angiotensinogen | chr1 | GO:0055067 | Not Cancer Driver | No | 85 | 0.179 | 33 | 10 | 0.303 | 1 |
| AQP11 | AQP11 | Q8NBQ7 | Aquaporin-11 | chr11 | GO:0055067 | Not Cancer Driver | No | 23 | 0.085 | 0 | 0 | 0.0 | 0 |
| ATP12A_ENST00000381946 | ATP12A | P54707 | Potassium-transporting ATPase alpha chain 2 | chr13 | GO:0055067 | Not Cancer Driver | No | 203 | 0.195 | 117 | 24 | 0.205 | 0 |
| ATP1A1_ENST00000295598 | ATP1A1 | P05023 | Sodium/potassium-transporting ATPase subunit alpha-1 | chr1 | GO:0055067 | Census | Yes | 115 | 0.112 | 115 | 16 | 0.139 | 6 |
| ATP1A2 | ATP1A2 | P50993 | Sodium/potassium-transporting ATPase subunit alpha-2 | chr1 | GO:0055067 | Not Cancer Driver | No | 230 | 0.225 | 161 | 34 | 0.211 | 8 |
| ATP1A3_ENST00000302102 | ATP1A3 | P13637 | Sodium/potassium-transporting ATPase subunit alpha-3 | chr19 | GO:0055067 | Not Cancer Driver | No | 200 | 0.197 | 115 | 29 | 0.252 | 31 |
| ATP1A4 | ATP1A4 | Q13733 | Sodium/potassium-transporting ATPase subunit alpha-4 | chr1 | GO:0055067 | Not Cancer Driver | No | 195 | 0.19 | 117 | 24 | 0.205 | 0 |
| ATP1B1 | ATP1B1 | P05026 | Sodium/potassium-transporting ATPase subunit beta-1 | chr1 | GO:0055067 | Not Cancer Driver | No | 38 | 0.125 | 55 | 9 | 0.164 | 0 |
| ATP1B2 | ATP1B2 | P14415 | Sodium/potassium-transporting ATPase subunit beta-2 | chr17 | GO:0055067 | Not Cancer Driver | No | 40 | 0.138 | 16 | 6 | 0.375 | 0 |
| ATP1B3 | ATP1B3 | P54709 | Sodium/potassium-transporting ATPase subunit beta-3 | chr3 | GO:0055067 | Not Cancer Driver | No | 36 | 0.129 | 6 | 1 | 0.167 | 0 |
| ATP4A | ATP4A | P20648 | Potassium-transporting ATPase alpha chain 1 | chr19 | GO:0055067 | Not Cancer Driver | No | 201 | 0.194 | 121 | 30 | 0.248 | 0 |
| ATP4B | ATP4B | P51164 | Potassium-transporting ATPase subunit beta | chr13 | GO:0055067 | Not Cancer Driver | No | 35 | 0.12 | 2 | 0 | 0.0 | 0 |
| ATP6AP2 | ATP6AP2 | O75787 | Renin receptor | chrX | GO:0055067 | Not Cancer Driver | No | 56 | 0.16 | 0 | 0 | 0.0 | 2 |
| ATP6V1B1 | ATP6V1B1 | P15313 | V-type proton ATPase subunit B, kidney isoform | chr2 | GO:0055067 | Not Cancer Driver | No | 77 | 0.15 | 66 | 14 | 0.212 | 9 |
| AVP | AVP | P01185 | Vasopressin-neurophysin 2-copeptin | chr20 | GO:0055067 | Not Cancer Driver | No | 14 | 0.085 | 26 | 0 | 0.0 | 39 |
| AVPR1A | AVPR1A | P37288 | Vasopressin V1a receptor | chr12 | GO:0055067 | Not Cancer Driver | No | 105 | 0.251 | 68 | 25 | 0.368 | 0 |
| AVPR1B | AVPR1B | P47901 | Vasopressin V1b receptor | chr1 | GO:0055067 | Not Cancer Driver | No | 83 | 0.196 | 51 | 5 | 0.098 | 0 |
| BCL2_ENST00000333681 | BCL2 | P10415 | Apoptosis regulator Bcl-2 | chr18 | GO:0055067 | Census, Compendium | Yes | 24 | 0.1 | 72 | 5 | 0.069 | 0 |
| CA2 | CA2 | P00918 | Carbonic anhydrase 2 | chr8 | GO:0055067 | Not Cancer Driver | No | 41 | 0.158 | 55 | 8 | 0.145 | 4 |
| CA7 | CA7 | P43166 | Carbonic anhydrase 7 | chr16 | GO:0055067 | Not Cancer Driver | No | 22 | 0.083 | 65 | 5 | 0.077 | 0 |
| CCDC115 | CCDC115 | Q96NT0 | Coiled-coil domain-containing protein 115 | chr2 | GO:0055067 | Not Cancer Driver | No | 21 | 0.117 | 89 | 8 | 0.09 | 2 |
| CFTR | CFTR | P13569 | Cystic fibrosis transmembrane conductance regulator | chr7 | GO:0055067 | Not Cancer Driver | No | 287 | 0.194 | 145 | 18 | 0.124 | 151 |
| CLCN3_ENST00000513761 | CLCN3 | P51790 | H(+)/Cl(-) exchange transporter 3 | chr4 | GO:0055067 | Not Cancer Driver | No | 105 | 0.128 | 88 | 7 | 0.08 | 0 |
| CLN3_ENST00000636147 | CLN3 | Q13286 | Battenin | chr16 | GO:0055067 | Not Cancer Driver | No | 58 | 0.132 | 69 | 10 | 0.145 | 9 |
| CLN5_ENST00000377453 | CLN5 | O75503 | Ceroid-lipofuscinosis neuronal protein 5 | chr13 | GO:0055067 | Not Cancer Driver | No | 39 | 0.109 | 16 | 1 | 0.062 | 12 |
| CLN6 | CLN6 | Q9NWW5 | Ceroid-lipofuscinosis neuronal protein 6 | chr15 | GO:0055067 | Not Cancer Driver | No | 28 | 0.09 | 13 | 0 | 0.0 | 24 |
| CXorf21 | TASL | Q9HAI6 | TLR adapter interacting with SLC15A4 on the lysosome | chrX | GO:0055067 | Not Cancer Driver | No | 73 | 0.243 | 66 | 21 | 0.318 | 0 |
| CYP11B2 | CYP11B2 | P19099 | Cytochrome P450 11B2, mitochondrial | chr8 | GO:0055067 | Not Cancer Driver | No | 148 | 0.294 | 6 | 0 | 0.0 | 6 |
| CYP4A11 | CYP4A11 | Q02928 | Cytochrome P450 4A11 | chr1 | GO:0055067 | Not Cancer Driver | No | 131 | 0.252 | 24 | 8 | 0.333 | 0 |
| CYP4F12_ENST00000324632 | CYP4F12 | Q9HCS2 | Cytochrome P450 4F12 | chr19 | GO:0055067 | Not Cancer Driver | No | 138 | 0.263 | 18 | 4 | 0.222 | 0 |
| CYP4F2 | CYP4F2 | P78329 | Cytochrome P450 4F2 | chr19 | GO:0055067 | Not Cancer Driver | No | 136 | 0.262 | 17 | 3 | 0.176 | 0 |
| EDNRA | EDNRA | P25101 | Endothelin-1 receptor | chr4 | GO:0055067 | Not Cancer Driver | No | 62 | 0.145 | 21 | 6 | 0.286 | 2 |
| EXT1 | EXT1 | Q16394 | Exostosin-1 | chr8 | GO:0055067 | Census | Yes | 107 | 0.143 | 58 | 7 | 0.121 | 12 |
| EXT2_ENST00000533608 | EXT2 | Q93063 | Exostosin-2 | chr11 | GO:0055067 | Census, Compendium | Yes | 93 | 0.13 | 12 | 1 | 0.083 | 9 |
| FASLG | FASLG | P48023 | Tumor necrosis factor ligand superfamily member 6 | chr1 | GO:0055067 | Not Cancer Driver | No | 65 | 0.231 | 94 | 18 | 0.191 | 1 |
| GRN | GRN | P28799 | Progranulin | chr17 | GO:0055067 | Not Cancer Driver | No | 76 | 0.128 | 29 | 6 | 0.207 | 1 |
| IL1A | IL1A | P01583 | Interleukin-1 alpha | chr2 | GO:0055067 | Not Cancer Driver | No | 30 | 0.111 | 35 | 6 | 0.171 | 0 |
| KCNA5 | KCNA5 | P22460 | Potassium voltage-gated channel subfamily A member 5 | chr12 | GO:0055067 | Not Cancer Driver | No | 213 | 0.347 | 218 | 53 | 0.243 | 0 |
| KCNH2 | KCNH2 | Q12809 | Potassium voltage-gated channel subfamily H member 2 | chr7 | GO:0055067 | Not Cancer Driver | No | 189 | 0.163 | 466 | 50 | 0.107 | 117 |
| KCNJ10 | KCNJ10 | P78508 | ATP-sensitive inward rectifier potassium channel 10 | chr1 | GO:0055067 | Not Cancer Driver | No | 78 | 0.206 | 28 | 10 | 0.357 | 8 |
| KCNJ2_ENST00000535240 | KCNJ2 | P63252 | Inward rectifier potassium channel 2 | chr17 | GO:0055067 | Not Cancer Driver | No | 103 | 0.241 | 49 | 11 | 0.224 | 12 |
| KCNMA1 | KCNMA1 | Q12791 | Calcium-activated potassium channel subunit alpha-1 | chr10 | GO:0055067 | Not Cancer Driver | No | 222 | 0.18 | 225 | 39 | 0.173 | 5 |
| KCNQ1 | KCNQ1 | P51787 | Potassium voltage-gated channel subfamily KQT member 1 | chr11 | GO:0055067 | Not Cancer Driver | No | 78 | 0.115 | 219 | 20 | 0.091 | 132 |
| KCTD7 | KCTD7 | Q96MP8 | BTB/POZ domain-containing protein KCTD7 | chr7 | GO:0055067 | Not Cancer Driver | No | 37 | 0.128 | 45 | 1 | 0.022 | 4 |
| LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | GO:0055067 | Not Cancer Driver | No | 519 | 0.205 | 90 | 17 | 0.189 | 23 |
| MC3R | MC3R | P41968 | Melanocortin receptor 3 | chr20 | GO:0055067 | Not Cancer Driver | No | 96 | 0.297 | 0 | 0 | 0.0 | 0 |
| NEDD4L | NEDD4L | Q96PU5 | E3 ubiquitin-protein ligase NEDD4-like | chr18 | GO:0055067 | Not Cancer Driver | No | 126 | 0.129 | 463 | 60 | 0.13 | 4 |
| NOX1 | NOX1 | Q9Y5S8 | NADPH oxidase 1 | chrX | GO:0055067 | Not Cancer Driver | No | 101 | 0.179 | 18 | 8 | 0.444 | 0 |
| OTC | OTC | P00480 | Ornithine transcarbamylase, mitochondrial | chrX | GO:0055067 | Not Cancer Driver | No | 89 | 0.251 | 24 | 4 | 0.167 | 111 |
| PPT1 | PPT1 | P50897 | Palmitoyl-protein thioesterase 1 | chr1 | GO:0055067 | Not Cancer Driver | No | 37 | 0.121 | 0 | 0 | 0.0 | 23 |
| RAB20 | RAB20 | Q9NX57 | Ras-related protein Rab-20 | chr13 | GO:0055067 | Not Cancer Driver | No | 33 | 0.141 | 57 | 8 | 0.14 | 0 |
| RAB38 | RAB38 | P57729 | Ras-related protein Rab-38 | chr11 | GO:0055067 | Not Cancer Driver | No | 27 | 0.128 | 0 | 0 | 0.0 | 0 |
| RAB39A | RAB39A | Q14964 | Ras-related protein Rab-39A | chr11 | GO:0055067 | Not Cancer Driver | No | 29 | 0.134 | 3 | 0 | 0.0 | 0 |
| RAB7A | RAB7A | P51149 | Ras-related protein Rab-7a | chr3 | GO:0055067 | Not Cancer Driver | No | 27 | 0.13 | 11 | 0 | 0.0 | 4 |
| RHAG | RHAG | Q02094 | Ammonium transporter Rh type A | chr6 | GO:0055067 | Not Cancer Driver | No | 102 | 0.249 | 0 | 0 | 0.0 | 6 |
| RHBG | RHBG | Q9H310 | Ammonium transporter Rh type B | chr1 | GO:0055067 | Not Cancer Driver | No | 66 | 0.144 | 32 | 7 | 0.219 | 0 |
| RHCE | RHCE | P18577 | Blood group Rh(CE) polypeptide | chr1 | GO:0055067 | Not Cancer Driver | No | 64 | 0.153 | 8 | 5 | 0.625 | 0 |
| RHCG | RHCG | Q9UBD6 | Ammonium transporter Rh type C | chr15 | GO:0055067 | Not Cancer Driver | No | 74 | 0.154 | 19 | 2 | 0.105 | 0 |
| RHD_ENST00000328664 | RHD | Q02161 | Blood group Rh(D) polypeptide | chr1 | GO:0055067 | Not Cancer Driver | No | 55 | 0.132 | 9 | 0 | 0.0 | 0 |
| SCN7A_ENST00000409855 | SCN7A | Q01118 | Sodium channel protein type 7 subunit alpha | chr2 | GO:0055067 | Not Cancer Driver | No | 395 | 0.235 | 171 | 43 | 0.251 | 0 |
| SCNN1A_ENST00000228916 | SCNN1A | P37088 | Amiloride-sensitive sodium channel subunit alpha | chr12 | GO:0055067 | Not Cancer Driver | No | 73 | 0.109 | 146 | 21 | 0.144 | 5 |
| SCNN1B | SCNN1B | P51168 | Amiloride-sensitive sodium channel subunit beta | chr16 | GO:0055067 | Not Cancer Driver | No | 90 | 0.141 | 62 | 4 | 0.065 | 13 |
| SCNN1D | SCNN1D | P51172 | Amiloride-sensitive sodium channel subunit delta | chr1 | GO:0055067 | Not Cancer Driver | No | 56 | 0.07 | 210 | 9 | 0.043 | 0 |
| SCNN1G | SCNN1G | P51170 | Amiloride-sensitive sodium channel subunit gamma | chr16 | GO:0055067 | Not Cancer Driver | No | 129 | 0.199 | 57 | 11 | 0.193 | 0 |
| SLAMF8 | SLAMF8 | Q9P0V8 | SLAM family member 8 | chr1 | GO:0055067 | Not Cancer Driver | No | 63 | 0.221 | 20 | 2 | 0.1 | 0 |
| SLC12A1_ENST00000380993 | SLC12A1 | Q13621 | Solute carrier family 12 member 1 | chr15 | GO:0055067 | Not Cancer Driver | No | 199 | 0.181 | 143 | 35 | 0.245 | 2 |
| SLC12A2 | SLC12A2 | P55011 | Solute carrier family 12 member 2 | chr5 | GO:0055067 | Not Cancer Driver | No | 141 | 0.116 | 297 | 18 | 0.061 | 8 |
| SLC12A3_ENST00000563236 | SLC12A3 | P55017 | Solute carrier family 12 member 3 | chr16 | GO:0055067 | Not Cancer Driver | No | 146 | 0.143 | 124 | 16 | 0.129 | 117 |
| SLC12A4_ENST00000316341 | SLC12A4 | Q9UP95 | Solute carrier family 12 member 4 | chr16 | GO:0055067 | Not Cancer Driver | No | 122 | 0.112 | 171 | 17 | 0.099 | 0 |
| SLC12A5 | SLC12A5 | Q9H2X9 | Solute carrier family 12 member 5 | chr20 | GO:0055067 | Not Cancer Driver | No | 263 | 0.231 | 290 | 59 | 0.203 | 5 |
| SLC12A6_ENST00000558667 | SLC12A6 | Q9UHW9 | Solute carrier family 12 member 6 | chr15 | GO:0055067 | Not Cancer Driver | No | 168 | 0.146 | 280 | 46 | 0.164 | 0 |
| SLC12A7 | SLC12A7 | Q9Y666 | Solute carrier family 12 member 7 | chr5 | GO:0055067 | Not Cancer Driver | No | 153 | 0.141 | 202 | 23 | 0.114 | 0 |
| SLC12A8 | SLC12A8 | A0AV02 | Solute carrier family 12 member 8 | chr3 | GO:0055067 | Not Cancer Driver | No | 98 | 0.137 | 93 | 10 | 0.108 | 0 |
| SLC12A9 | SLC12A9 | Q9BXP2 | Solute carrier family 12 member 9 | chr7 | GO:0055067 | Not Cancer Driver | No | 117 | 0.128 | 174 | 8 | 0.046 | 0 |
| SLC1A3 | SLC1A3 | P43003 | Excitatory amino acid transporter 1 | chr5 | GO:0055067 | Not Cancer Driver | No | 100 | 0.185 | 55 | 9 | 0.164 | 1 |
| SLC26A3 | SLC26A3 | P40879 | Chloride anion exchanger | chr7 | GO:0055067 | Not Cancer Driver | No | 159 | 0.208 | 3 | 1 | 0.333 | 26 |
| SLC26A6 | SLC26A6 | Q9BXS9 | Solute carrier family 26 member 6 | chr3 | GO:0055067 | Not Cancer Driver | No | 68 | 0.09 | 87 | 13 | 0.149 | 0 |
| SLC4A1 | SLC4A1 | P02730 | Band 3 anion transport protein | chr17 | GO:0055067 | Not Cancer Driver | No | 153 | 0.168 | 130 | 23 | 0.177 | 39 |
| SLC8A1_ENST00000332839 | SLC8A1 | P32418 | Sodium/calcium exchanger 1 | chr2 | GO:0055067 | Not Cancer Driver | No | 305 | 0.313 | 158 | 48 | 0.304 | 0 |
| SLC9A1 | SLC9A1 | P19634 | Sodium/hydrogen exchanger 1 | chr1 | GO:0055067 | Not Cancer Driver | No | 89 | 0.109 | 251 | 29 | 0.116 | 1 |
| SLC9A4 | SLC9A4 | Q6AI14 | Sodium/hydrogen exchanger 4 | chr2 | GO:0055067 | Not Cancer Driver | No | 197 | 0.247 | 197 | 77 | 0.391 | 0 |
| SLC9A7_ENST00000328306 | SLC9A7 | Q96T83 | Sodium/hydrogen exchanger 7 | chrX | GO:0055067 | Not Cancer Driver | No | 102 | 0.141 | 180 | 29 | 0.161 | 1 |
| SNAPIN | SNAPIN | O95295 | SNARE-associated protein Snapin | chr1 | GO:0055067 | Not Cancer Driver | No | 9 | 0.066 | 62 | 5 | 0.081 | 0 |
| TCIRG1 | TCIRG1 | Q13488 | V-type proton ATPase 116 kDa subunit a 3 | chr11 | GO:0055067 | Compendium | Yes | 68 | 0.082 | 102 | 6 | 0.059 | 5 |
| TFAP2B | TFAP2B | Q92481 | Transcription factor AP-2-beta | chr6 | GO:0055067 | Not Cancer Driver | No | 114 | 0.248 | 306 | 75 | 0.245 | 6 |
| TMEM106B | TMEM106B | Q9NUM4 | Transmembrane protein 106B | chr7 | GO:0055067 | Not Cancer Driver | No | 31 | 0.113 | 56 | 4 | 0.071 | 1 |
| TMEM165 | TMEM165 | Q9HC07 | Transmembrane protein 165 | chr4 | GO:0055067 | Not Cancer Driver | No | 29 | 0.09 | 75 | 5 | 0.067 | 3 |
| TMEM175 | TMEM175 | Q9BSA9 | Endosomal/lysosomal potassium channel TMEM175 | chr4 | GO:0055067 | Not Cancer Driver | No | 77 | 0.153 | 51 | 13 | 0.255 | 0 |
| TMEM199 | TMEM199 | Q8N511 | Transmembrane protein 199 | chr17 | GO:0055067 | Not Cancer Driver | No | 24 | 0.115 | 54 | 5 | 0.093 | 3 |
| TMEM9_ENST00000485839 | TMEM9 | Q9P0T7 | Proton-transporting V-type ATPase complex assembly regulator TMEM9 | chr1 | GO:0055067 | Not Cancer Driver | No | 22 | 0.12 | 23 | 3 | 0.13 | 0 |
| TMPRSS3_ENST00000433957 | TMPRSS3 | P57727 | Transmembrane protease serine 3 | chr21 | GO:0055067 | Not Cancer Driver | No | 78 | 0.172 | 8 | 3 | 0.375 | 8 |
| UBE3A | UBE3A | Q05086 | Ubiquitin-protein ligase E3A | chr15 | GO:0055067 | Not Cancer Driver | No | 141 | 0.161 | 136 | 22 | 0.162 | 0 |
| UPK3A | UPK3A | O75631 | Uroplakin-3a | chr22 | GO:0055067 | Not Cancer Driver | No | 39 | 0.136 | 66 | 11 | 0.167 | 0 |
| VPS33A | VPS33A | Q96AX1 | Vacuolar protein sorting-associated protein 33A | chr12 | GO:0055067 | Not Cancer Driver | No | 73 | 0.122 | 46 | 8 | 0.174 | 1 |