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Total number of protein in "GO:0051928" GO term:  114

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0051928 Census, Compendium Yes 139 0.123 604 73 0.121 2
ADCYAP1R1_ENST00000304166 ADCYAP1R1 P41586 Pituitary adenylate cyclase-activating polypeptide type I receptor chr7 GO:0051928 Not Cancer Driver No 127 0.271 0 0 0.0 0
AKAP6 AKAP6 Q13023 A-kinase anchor protein 6 chr14 GO:0051928 Not Cancer Driver No 383 0.165 1456 240 0.165 0
ANK2 ANK2 Q01484 Ankyrin-2 chr4 GO:0051928 Not Cancer Driver No 770 0.195 2844 566 0.199 4
APLNR APLNR P35414 Apelin receptor chr11 GO:0051928 Not Cancer Driver No 96 0.253 29 8 0.276 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0051928 Not Cancer Driver No 46 0.112 122 22 0.18 0
ATP1B1 ATP1B1 P05026 Sodium/potassium-transporting ATPase subunit beta-1 chr1 GO:0051928 Not Cancer Driver No 38 0.125 55 9 0.164 0
ATP2A1 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 GO:0051928 Not Cancer Driver No 157 0.157 80 11 0.138 1
ATP2B1_ENST00000261173 ATP2B1 P20020 Plasma membrane calcium-transporting ATPase 1 chr12 GO:0051928 Not Cancer Driver No 143 0.117 293 42 0.143 0
ATP2C2_ENST00000262429 ATP2C2 O75185 Calcium-transporting ATPase type 2C member 2 chr16 GO:0051928 Not Cancer Driver No 123 0.13 54 6 0.111 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0051928 Not Cancer Driver No 38 0.18 58 9 0.155 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0051928 Census Yes 30 0.156 39 2 0.051 0
BDKRB1_ENST00000611804 BDKRB1 P46663 B1 bradykinin receptor chr14 GO:0051928 Not Cancer Driver No 68 0.193 3 0 0.0 0
CACNA1D_ENST00000350061 CACNA1D Q01668 Voltage-dependent L-type calcium channel subunit alpha-1D chr3 GO:0051928 Census, Compendium Yes 342 0.158 736 126 0.171 2
CACNA2D1_ENST00000356253 CACNA2D1 P54289 Voltage-dependent calcium channel subunit alpha-2/delta-1 chr7 GO:0051928 Not Cancer Driver No 277 0.251 99 25 0.253 0
CACNB2 CACNB2 Q08289 Voltage-dependent L-type calcium channel subunit beta-2 chr10 GO:0051928 Not Cancer Driver No 155 0.235 478 106 0.222 0
CACNB3 CACNB3 P54284 Voltage-dependent L-type calcium channel subunit beta-3 chr12 GO:0051928 Not Cancer Driver No 58 0.12 258 30 0.116 0
CALCR_ENST00000394441 CALCR P30988 Calcitonin receptor chr7 GO:0051928 Not Cancer Driver No 162 0.342 29 9 0.31 0
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 GO:0051928 Not Cancer Driver No 19 0.128 115 15 0.13 7
CALM2 CALM2 P0DP24 Calmodulin-2 chr2 GO:0051928 Not Cancer Driver No 18 0.121 115 13 0.113 8
CALM3_ENST00000596362 CALM3 P0DP25 Calmodulin-3 chr19 GO:0051928 Not Cancer Driver No 17 0.114 115 10 0.087 3
CAMK2A_ENST00000348628 CAMK2A Q9UQM7 Calcium/calmodulin-dependent protein kinase type II subunit alpha chr5 GO:0051928 Not Cancer Driver No 83 0.174 62 10 0.161 7
CAPN3 CAPN3 P20807 Calpain-3 chr15 GO:0051928 Not Cancer Driver No 111 0.135 168 11 0.065 52
CASK_ENST00000378163 CASK O14936 Peripheral plasma membrane protein CASK chrX GO:0051928 Not Cancer Driver No 118 0.127 285 45 0.158 4
CASQ1 CASQ1 P31415 Calsequestrin-1 chr1 GO:0051928 Not Cancer Driver No 77 0.194 110 18 0.164 4
CASR_ENST00000638421 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0051928 Not Cancer Driver No 304 0.282 189 60 0.317 108
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0051928 Not Cancer Driver No 30 0.169 2 0 0.0 0
CCL2 CCL2 P13500 C-C motif chemokine 2 chr17 GO:0051928 Not Cancer Driver No 20 0.202 15 5 0.333 0
CCR1 CCR1 P32246 C-C chemokine receptor type 1 chr3 GO:0051928 Not Cancer Driver No 69 0.194 14 5 0.357 0
CD19_ENST00000324662 CD19 P15391 B-lymphocyte antigen CD19 chr16 GO:0051928 Not Cancer Driver No 80 0.144 312 46 0.147 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0051928 Not Cancer Driver No 48 0.164 5 1 0.2 0
CEMIP_ENST00000356249 CEMIP Q8WUJ3 Cell migration-inducing and hyaluronan-binding protein chr15 GO:0051928 Not Cancer Driver No 207 0.152 105 10 0.095 0
CRACR2A CRACR2A Q9BSW2 EF-hand calcium-binding domain-containing protein 4B chr12 GO:0051928 Not Cancer Driver No 88 0.12 436 60 0.138 0
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0051928 Not Cancer Driver No 66 0.166 259 44 0.17 0
CXCL10 CXCL10 P02778 C-X-C motif chemokine 10 chr4 GO:0051928 Not Cancer Driver No 19 0.194 12 4 0.333 0
CXCL11 CXCL11 O14625 C-X-C motif chemokine 11 chr4 GO:0051928 Not Cancer Driver No 13 0.138 0 0 0.0 0
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:0051928 Not Cancer Driver No 16 0.172 0 0 0.0 0
CXCL9 CXCL9 Q07325 C-X-C motif chemokine 9 chr4 GO:0051928 Not Cancer Driver No 32 0.256 38 16 0.421 0
DRD1 DRD1 P21728 D(1A) dopamine receptor chr5 GO:0051928 Not Cancer Driver No 73 0.164 30 4 0.133 0
EHD3 EHD3 Q9NZN3 EH domain-containing protein 3 chr2 GO:0051928 Not Cancer Driver No 104 0.194 77 18 0.234 0
F2 F2 P00734 Prothrombin chr11 GO:0051928 Not Cancer Driver No 115 0.185 97 25 0.258 10
F2R F2R P25116 Proteinase-activated receptor 1 chr5 GO:0051928 Not Cancer Driver No 73 0.172 19 2 0.105 0
F2RL3 F2RL3 Q96RI0 Proteinase-activated receptor 4 chr19 GO:0051928 Not Cancer Driver No 43 0.112 46 4 0.087 0
FFAR1 FFAR1 O14842 Free fatty acid receptor 1 chr19 GO:0051928 Not Cancer Driver No 45 0.15 2 0 0.0 0
G6PD_ENST00000621232 G6PD P11413 Glucose-6-phosphate 1-dehydrogenase chrX GO:0051928 Not Cancer Driver No 86 0.167 28 3 0.107 58
GCG GCG P01275 Pro-glucagon chr2 GO:0051928 Not Cancer Driver No 49 0.272 82 22 0.268 0
GJC2 GJC2 Q5T442 Gap junction gamma-2 protein chr1 GO:0051928 Not Cancer Driver No 33 0.075 225 10 0.044 6
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0051928 Not Cancer Driver No 65 0.173 13 5 0.385 0
GRIN1_ENST00000371561 GRIN1 Q05586 Glutamate receptor ionotropic, NMDA 1 chr9 GO:0051928 Not Cancer Driver No 88 0.094 190 15 0.079 13
GRM6_ENST00000517717 GRM6 O15303 Metabotropic glutamate receptor 6 chr5 GO:0051928 Not Cancer Driver No 200 0.228 113 23 0.204 6
GSTM2 GSTM2 P28161 Glutathione S-transferase Mu 2 chr1 GO:0051928 Not Cancer Driver No 26 0.119 5 0 0.0 0
GSTO1 GSTO1 P78417 Glutathione S-transferase omega-1 chr10 GO:0051928 Not Cancer Driver No 26 0.108 18 1 0.056 0
HAP1_ENST00000310778 HAP1 P54257 Huntingtin-associated protein 1 chr17 GO:0051928 Not Cancer Driver No 97 0.145 454 60 0.132 0
HCRT HCRT O43612 Orexin chr17 GO:0051928 Not Cancer Driver No 3 0.023 45 0 0.0 1
HOMER1 HOMER1 Q86YM7 Homer protein homolog 1 chr5 GO:0051928 Not Cancer Driver No 46 0.13 243 32 0.132 0
HSPA2_ENST00000247207 HSPA2 P54652 Heat shock-related 70 kDa protein 2 chr14 GO:0051928 Not Cancer Driver No 93 0.146 286 38 0.133 0
HTT HTT P42858 Huntingtin chr4 GO:0051928 Not Cancer Driver No 336 0.107 666 69 0.104 2
IL13 IL13 P35225 Interleukin-13 chr5 GO:0051928 Not Cancer Driver No 20 0.137 0 0 0.0 0
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 GO:0051928 Census, Compendium Yes 167 0.149 63 10 0.159 7
JPH2 JPH2 Q9BR39 Junctophilin-2 chr20 GO:0051928 Not Cancer Driver No 137 0.197 542 97 0.179 4
KCNE2 KCNE2 Q9Y6J6 Potassium voltage-gated channel subfamily E member 2 chr21 GO:0051928 Not Cancer Driver No 25 0.203 2 0 0.0 5
LACRT LACRT Q9GZZ8 Extracellular glycoprotein lacritin chr12 GO:0051928 Not Cancer Driver No 38 0.275 90 27 0.3 0
LGALS3 LGALS3 P17931 Galectin-3 chr14 GO:0051928 Not Cancer Driver No 15 0.06 133 6 0.045 0
LILRA2 LILRA2 Q8N149 Leukocyte immunoglobulin-like receptor subfamily A member 2 chr19 GO:0051928 Not Cancer Driver No 163 0.337 137 44 0.321 0
LILRA5 LILRA5 A6NI73 Leukocyte immunoglobulin-like receptor subfamily A member 5 chr19 GO:0051928 Not Cancer Driver No 79 0.264 98 19 0.194 0
MCHR1 MCHR1 Q99705 Melanin-concentrating hormone receptor 1 chr22 GO:0051928 Not Cancer Driver No 64 0.152 100 12 0.12 0
MYLK MYLK Q15746 Myosin light chain kinase, smooth muscle chr3 GO:0051928 Not Cancer Driver No 343 0.179 957 184 0.192 3
NIPSNAP2 NIPSNAP2 O75323 Protein NipSnap homolog 2 chr7 GO:0051928 Not Cancer Driver No 30 0.105 6 1 0.167 0
NPSR1_ENST00000360581 NPSR1 Q6W5P4 Neuropeptide S receptor chr7 GO:0051928 Not Cancer Driver No 111 0.299 9 7 0.778 0
NTSR1 NTSR1 P30989 Neurotensin receptor type 1 chr20 GO:0051928 Not Cancer Driver No 85 0.203 23 1 0.043 0
ORAI1 ORAI1 Q96D31 Calcium release-activated calcium channel protein 1 chr12 GO:0051928 Not Cancer Driver No 26 0.086 101 9 0.089 5
P2RX1 P2RX1 P51575 P2X purinoceptor 1 chr17 GO:0051928 Not Cancer Driver No 59 0.148 14 1 0.071 0
P2RX2_ENST00000643471 P2RX2 Q9UBL9 P2X purinoceptor 2 chr12 GO:0051928 Not Cancer Driver No 62 0.132 104 13 0.125 2
P2RX3 P2RX3 P56373 P2X purinoceptor 3 chr11 GO:0051928 Not Cancer Driver No 85 0.214 15 6 0.4 0
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 GO:0051928 Not Cancer Driver No 36 0.093 0 0 0.0 0
P2RX5 P2RX5 Q93086 P2X purinoceptor 5 chr17 GO:0051928 Not Cancer Driver No 58 0.137 73 14 0.192 0
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0051928 Not Cancer Driver No 51 0.086 14 2 0.143 0
P2RY6_ENST00000540342 P2RY6 Q15077 P2Y purinoceptor 6 chr11 GO:0051928 Not Cancer Driver No 50 0.152 10 5 0.5 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0051928 Census Yes 37 0.154 99 22 0.222 2
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0051928 Census, Compendium Yes 164 0.148 231 44 0.19 7
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0051928 Not Cancer Driver No 33 0.059 121 12 0.099 0
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0051928 Not Cancer Driver No 113 0.117 375 35 0.093 10
PLA2G1B PLA2G1B P04054 Phospholipase A2 chr12 GO:0051928 Not Cancer Driver No 17 0.115 0 0 0.0 0
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 GO:0051928 Census, Compendium Yes 158 0.122 186 21 0.113 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0051928 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLP1 PLP1 P60201 Myelin proteolipid protein chrX GO:0051928 Not Cancer Driver No 49 0.177 5 1 0.2 72
RAMP3 RAMP3 O60896 Receptor activity-modifying protein 3 chr7 GO:0051928 Not Cancer Driver No 30 0.203 0 0 0.0 0
RGN RGN Q15493 Regucalcin chrX GO:0051928 Not Cancer Driver No 38 0.127 14 3 0.214 0
RYR2 RYR2 Q92736 Ryanodine receptor 2 chr1 GO:0051928 Not Cancer Driver No 1703 0.343 782 281 0.359 51
SLC9A1 SLC9A1 P19634 Sodium/hydrogen exchanger 1 chr1 GO:0051928 Not Cancer Driver No 89 0.109 251 29 0.116 1
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0051928 Not Cancer Driver No 21 0.15 107 13 0.121 5
SPHK2 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 GO:0051928 Not Cancer Driver No 82 0.125 293 39 0.133 0
SRI SRI P30626 Sorcin chr7 GO:0051928 Not Cancer Driver No 15 0.076 32 2 0.062 0
STAC STAC Q99469 SH3 and cysteine-rich domain-containing protein chr3 GO:0051928 Not Cancer Driver No 107 0.266 196 55 0.281 0
STAC2 STAC2 Q6ZMT1 SH3 and cysteine-rich domain-containing protein 2 chr17 GO:0051928 Not Cancer Driver No 56 0.136 228 36 0.158 0
STAC3 STAC3 Q96MF2 SH3 and cysteine-rich domain-containing protein 3 chr12 GO:0051928 Not Cancer Driver No 50 0.137 192 30 0.156 1
STC1 STC1 P52823 Stanniocalcin-1 chr8 GO:0051928 Not Cancer Driver No 59 0.239 58 12 0.207 0
STIM1_ENST00000300737 STIM1 Q13586 Stromal interaction molecule 1 chr11 GO:0051928 Not Cancer Driver No 70 0.102 387 45 0.116 13
STIM2_ENST00000467087 STIM2 Q9P246 Stromal interaction molecule 2 chr4 GO:0051928 Not Cancer Driver No 82 0.11 387 45 0.116 0
STIMATE STIMATE Q86TL2 Store-operated calcium entry regulator STIMATE chr3 GO:0051928 Not Cancer Driver No 27 0.092 61 4 0.066 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 GO:0051928 Not Cancer Driver No 10 0.099 76 7 0.092 0
THY1 THY1 P04216 Thy-1 membrane glycoprotein chr11 GO:0051928 Not Cancer Driver No 24 0.149 5 0 0.0 0
TRDN TRDN Q13061 Triadin chr6 GO:0051928 Not Cancer Driver No 129 0.177 639 102 0.16 1
TRPC1 TRPC1 P48995 Short transient receptor potential channel 1 chr3 GO:0051928 Not Cancer Driver No 143 0.18 52 11 0.212 0
TRPC3_ENST00000264811 TRPC3 Q13507 Short transient receptor potential channel 3 chr4 GO:0051928 Not Cancer Driver No 200 0.239 23 2 0.087 1
TRPC6 TRPC6 Q9Y210 Short transient receptor potential channel 6 chr11 GO:0051928 Not Cancer Driver No 202 0.217 165 46 0.279 10
TRPV2 TRPV2 Q9Y5S1 Transient receptor potential cation channel subfamily V member 2 chr17 GO:0051928 Not Cancer Driver No 105 0.137 175 23 0.131 0
TRPV3_ENST00000576742 TRPV3 Q8NET8 Transient receptor potential cation channel subfamily V member 3 chr17 GO:0051928 Not Cancer Driver No 127 0.161 177 36 0.203 4
TSPO_ENST00000329563 TSPO P30536 Translocator protein chr22 GO:0051928 Not Cancer Driver No 5 0.03 1 0 0.0 0
UCN UCN P55089 Urocortin chr2 GO:0051928 Not Cancer Driver No 7 0.056 61 4 0.066 0
VMP1 VMP1 Q96GC9 Vacuole membrane protein 1 chr17 GO:0051928 Not Cancer Driver No 57 0.14 68 11 0.162 0
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 GO:0051928 Not Cancer Driver No 105 0.118 203 10 0.049 39
WNK3_ENST00000375159 WNK3 Q9BYP7 Serine/threonine-protein kinase WNK3 chrX GO:0051928 Not Cancer Driver No 281 0.156 1281 200 0.156 0
XCL1 XCL1 P47992 Lymphotactin chr1 GO:0051928 Not Cancer Driver No 28 0.246 35 11 0.314 0