Total number of protein in "GO:0051897" GO term: 107
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADAM8 | ADAM8 | P78325 | Disintegrin and metalloproteinase domain-containing protein 8 | chr10 | GO:0051897 | Not Cancer Driver | No | 82 | 0.1 | 230 | 13 | 0.057 | 0 |
| AKR1C2 | AKR1C2 | P52895 | Aldo-keto reductase family 1 member C2 | chr10 | GO:0051897 | Not Cancer Driver | No | 32 | 0.099 | 1 | 0 | 0.0 | 4 |
| AKR1C3 | AKR1C3 | P42330 | Aldo-keto reductase family 1 member C3 | chr10 | GO:0051897 | Not Cancer Driver | No | 49 | 0.152 | 11 | 1 | 0.091 | 0 |
| ANGPT1 | ANGPT1 | Q15389 | Angiopoietin-1 | chr8 | GO:0051897 | Not Cancer Driver | No | 130 | 0.261 | 131 | 24 | 0.183 | 1 |
| ARRB2_ENST00000269260 | ARRB2 | P32121 | Beta-arrestin-2 | chr17 | GO:0051897 | Not Cancer Driver | No | 46 | 0.112 | 122 | 22 | 0.18 | 0 |
| AXL | AXL | P30530 | Tyrosine-protein kinase receptor UFO | chr19 | GO:0051897 | Not Cancer Driver | No | 168 | 0.188 | 341 | 64 | 0.188 | 0 |
| BAG4 | BAG4 | O95429 | BAG family molecular chaperone regulator 4 | chr8 | GO:0051897 | Not Cancer Driver | No | 55 | 0.12 | 402 | 49 | 0.122 | 0 |
| C1QBP | C1QBP | Q07021 | Complement component 1 Q subcomponent-binding protein, mitochondrial | chr17 | GO:0051897 | Not Cancer Driver | No | 14 | 0.05 | 103 | 6 | 0.058 | 2 |
| C1QTNF12 | C1QTNF12 | Q5T7M4 | Adipolin | chr1 | GO:0051897 | Not Cancer Driver | No | 13 | 0.043 | 105 | 5 | 0.048 | 0 |
| C1QTNF1_ENST00000581774 | C1QTNF1 | Q9BXJ1 | Complement C1q tumor necrosis factor-related protein 1 | chr17 | GO:0051897 | Not Cancer Driver | No | 61 | 0.217 | 96 | 17 | 0.177 | 0 |
| CALCR_ENST00000394441 | CALCR | P30988 | Calcitonin receptor | chr7 | GO:0051897 | Not Cancer Driver | No | 162 | 0.342 | 29 | 9 | 0.31 | 0 |
| CASS4 | CASS4 | Q9NQ75 | Cas scaffolding protein family member 4 | chr20 | GO:0051897 | Not Cancer Driver | No | 204 | 0.26 | 496 | 137 | 0.276 | 0 |
| CCL19 | CCL19 | Q99731 | C-C motif chemokine 19 | chr9 | GO:0051897 | Not Cancer Driver | No | 10 | 0.102 | 7 | 0 | 0.0 | 0 |
| CCL21 | CCL21 | O00585 | C-C motif chemokine 21 | chr9 | GO:0051897 | Not Cancer Driver | No | 14 | 0.104 | 59 | 6 | 0.102 | 0 |
| CCR7 | CCR7 | P32248 | C-C chemokine receptor type 7 | chr17 | GO:0051897 | Census, Compendium | Yes | 50 | 0.132 | 0 | 0 | 0.0 | 0 |
| CD28 | CD28 | P10747 | T-cell-specific surface glycoprotein CD28 | chr2 | GO:0051897 | Census | Yes | 42 | 0.191 | 18 | 10 | 0.556 | 0 |
| CHI3L1 | CHI3L1 | P36222 | Chitinase-3-like protein 1 | chr1 | GO:0051897 | Not Cancer Driver | No | 66 | 0.172 | 24 | 5 | 0.208 | 0 |
| CPNE1_ENST00000352393 | CPNE1 | Q99829 | Copine-1 | chr20 | GO:0051897 | Not Cancer Driver | No | 74 | 0.138 | 80 | 7 | 0.087 | 0 |
| CSF3 | CSF3 | P09919 | Granulocyte colony-stimulating factor | chr17 | GO:0051897 | Not Cancer Driver | No | 20 | 0.097 | 7 | 0 | 0.0 | 0 |
| CX3CL1 | CX3CL1 | P78423 | Fractalkine | chr16 | GO:0051897 | Not Cancer Driver | No | 66 | 0.166 | 259 | 44 | 0.17 | 0 |
| CX3CR1_ENST00000542107 | CX3CR1 | P49238 | CX3C chemokine receptor 1 | chr3 | GO:0051897 | Not Cancer Driver | No | 80 | 0.225 | 0 | 0 | 0.0 | 0 |
| EGF | EGF | P01133 | Pro-epidermal growth factor | chr4 | GO:0051897 | Not Cancer Driver | No | 184 | 0.152 | 191 | 25 | 0.131 | 1 |
| EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | GO:0051897 | Census, Compendium | Yes | 444 | 0.367 | 223 | 35 | 0.157 | 1 |
| ENG | ENG | P17813 | Endoglin | chr9 | GO:0051897 | Not Cancer Driver | No | 60 | 0.091 | 114 | 15 | 0.132 | 32 |
| F10 | F10 | P00742 | Coagulation factor X | chr13 | GO:0051897 | Not Cancer Driver | No | 98 | 0.201 | 120 | 24 | 0.2 | 26 |
| F3 | F3 | P13726 | Tissue factor | chr1 | GO:0051897 | Not Cancer Driver | No | 28 | 0.095 | 61 | 7 | 0.115 | 0 |
| F7 | F7 | P08709 | Coagulation factor VII | chr13 | GO:0051897 | Not Cancer Driver | No | 74 | 0.159 | 50 | 7 | 0.14 | 108 |
| FAM110C | FAM110C | Q1W6H9 | Protein FAM110C | chr2 | GO:0051897 | Not Cancer Driver | No | 33 | 0.103 | 286 | 32 | 0.112 | 0 |
| FERMT2_ENST00000395631 | FERMT2 | Q96AC1 | Fermitin family homolog 2 | chr14 | GO:0051897 | Not Cancer Driver | No | 71 | 0.104 | 101 | 10 | 0.099 | 0 |
| FGF2_ENST00000614010 | FGF2 | P09038 | Fibroblast growth factor 2 | chr4 | GO:0051897 | Not Cancer Driver | No | 18 | 0.062 | 183 | 5 | 0.027 | 0 |
| FGFR1_ENST00000447712 | FGFR1 | P11362 | Fibroblast growth factor receptor 1 | chr8 | GO:0051897 | Census, Compendium | Yes | 152 | 0.185 | 230 | 43 | 0.187 | 74 |
| GAS6 | GAS6 | Q14393 | Growth arrest-specific protein 6 | chr13 | GO:0051897 | Not Cancer Driver | No | 82 | 0.121 | 42 | 6 | 0.143 | 0 |
| GATA3_ENST00000346208 | GATA3 | P23771 | Trans-acting T-cell-specific transcription factor GATA-3 | chr10 | GO:0051897 | Census, Compendium | Yes | 111 | 0.251 | 364 | 87 | 0.239 | 2 |
| GCNT2_ENST00000379597 | GCNT2 | Q8N0V5 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase | chr6 | GO:0051897 | Not Cancer Driver | No | 40 | 0.1 | 3 | 0 | 0.0 | 0 |
| GDF15 | GDF15 | Q99988 | Growth/differentiation factor 15 | chr19 | GO:0051897 | Not Cancer Driver | No | 39 | 0.127 | 143 | 20 | 0.14 | 0 |
| GFRAL | GFRAL | Q6UXV0 | GDNF family receptor alpha-like | chr6 | GO:0051897 | Not Cancer Driver | No | 176 | 0.447 | 5 | 2 | 0.4 | 0 |
| GPX1_ENST00000620890 | GPX1 | P07203 | Glutathione peroxidase 1 | chr3 | GO:0051897 | Not Cancer Driver | No | 38 | 0.187 | 12 | 1 | 0.083 | 0 |
| HAX1 | HAX1 | O00165 | HCLS1-associated protein X-1 | chr1 | GO:0051897 | Not Cancer Driver | No | 44 | 0.158 | 219 | 32 | 0.146 | 2 |
| HBEGF | HBEGF | Q99075 | Proheparin-binding EGF-like growth factor | chr5 | GO:0051897 | Not Cancer Driver | No | 16 | 0.077 | 63 | 3 | 0.048 | 0 |
| HCLS1 | HCLS1 | P14317 | Hematopoietic lineage cell-specific protein | chr3 | GO:0051897 | Not Cancer Driver | No | 103 | 0.212 | 446 | 94 | 0.211 | 0 |
| HIP1 | HIP1 | O00291 | Huntingtin-interacting protein 1 | chr7 | GO:0051897 | Census, Compendium | Yes | 137 | 0.132 | 510 | 70 | 0.137 | 0 |
| HPSE | HPSE | Q9Y251 | Heparanase | chr4 | GO:0051897 | Not Cancer Driver | No | 90 | 0.166 | 16 | 2 | 0.125 | 0 |
| HSP90AA1_ENST00000216281 | HSP90AA1 | P07900 | Heat shock protein HSP 90-alpha | chr14 | GO:0051897 | Census, Compendium | Yes | 106 | 0.145 | 257 | 37 | 0.144 | 0 |
| HSP90AB1 | HSP90AB1 | P08238 | Heat shock protein HSP 90-beta | chr6 | GO:0051897 | Census, Compendium | Yes | 100 | 0.138 | 254 | 43 | 0.169 | 0 |
| IAPP_ENST00000539393 | IAPP | P10997 | Islet amyloid polypeptide | chr12 | GO:0051897 | Not Cancer Driver | No | 22 | 0.247 | 10 | 2 | 0.2 | 0 |
| IGF1R | IGF1R | P08069 | Insulin-like growth factor 1 receptor | chr15 | GO:0051897 | Not Cancer Driver | No | 183 | 0.134 | 265 | 37 | 0.14 | 6 |
| IGF2_ENST00000641326 | IGF2 | P01344 | Insulin-like growth factor II | chr11 | GO:0051897 | Not Cancer Driver | No | 39 | 0.217 | 44 | 12 | 0.273 | 0 |
| IGFBP5 | IGFBP5 | P24593 | Insulin-like growth factor-binding protein 5 | chr2 | GO:0051897 | Not Cancer Driver | No | 27 | 0.099 | 112 | 17 | 0.152 | 0 |
| IL18 | IL18 | Q14116 | Interleukin-18 | chr11 | GO:0051897 | Not Cancer Driver | No | 19 | 0.098 | 16 | 3 | 0.188 | 0 |
| IL26 | IL26 | Q9NPH9 | Interleukin-26 | chr12 | GO:0051897 | Not Cancer Driver | No | 38 | 0.222 | 0 | 0 | 0.0 | 0 |
| INS | INS | P01308 | Insulin | chr11 | GO:0051897 | Not Cancer Driver | No | 15 | 0.136 | 5 | 1 | 0.2 | 22 |
| INSR | INSR | P06213 | Insulin receptor | chr19 | GO:0051897 | Not Cancer Driver | No | 190 | 0.137 | 280 | 57 | 0.204 | 64 |
| ITGB1BP1_ENST00000355346 | ITGB1BP1 | O14713 | Integrin beta-1-binding protein 1 | chr2 | GO:0051897 | Not Cancer Driver | No | 26 | 0.13 | 58 | 11 | 0.19 | 0 |
| ITGB1_ENST00000302278 | ITGB1 | P05556 | Integrin beta-1 | chr10 | GO:0051897 | Not Cancer Driver | No | 103 | 0.129 | 84 | 10 | 0.119 | 0 |
| LEP | LEP | P41159 | Leptin | chr7 | GO:0051897 | Not Cancer Driver | No | 29 | 0.174 | 0 | 0 | 0.0 | 2 |
| LIN28A_ENST00000254231 | LIN28A | Q9H9Z2 | Protein lin-28 homolog A | chr1 | GO:0051897 | Not Cancer Driver | No | 37 | 0.177 | 86 | 12 | 0.14 | 0 |
| LRP2 | LRP2 | P98164 | Low-density lipoprotein receptor-related protein 2 | chr2 | GO:0051897 | Not Cancer Driver | No | 998 | 0.214 | 209 | 40 | 0.191 | 1 |
| MAZ_ENST00000322945 | MAZ | P56270 | Myc-associated zinc finger protein | chr16 | GO:0051897 | Not Cancer Driver | No | 46 | 0.096 | 249 | 22 | 0.088 | 0 |
| MC1R_ENST00000639847 | MC1R | Q01726 | Melanocyte-stimulating hormone receptor | chr16 | GO:0051897 | Not Cancer Driver | No | 39 | 0.123 | 0 | 0 | 0.0 | 5 |
| MEIS3_ENST00000558555 | MEIS3 | Q99687 | Homeobox protein Meis3 | chr19 | GO:0051897 | Not Cancer Driver | No | 54 | 0.144 | 247 | 43 | 0.174 | 0 |
| MET_ENST00000397752 | MET | P08581 | Hepatocyte growth factor receptor | chr7 | GO:0051897 | Census, Compendium | Yes | 226 | 0.163 | 62 | 15 | 0.242 | 19 |
| MFHAS1 | MFHAS1 | Q9Y4C4 | Malignant fibrous histiocytoma-amplified sequence 1 | chr8 | GO:0051897 | Not Cancer Driver | No | 95 | 0.09 | 98 | 9 | 0.092 | 0 |
| MST1R | MST1R | Q04912 | Macrophage-stimulating protein receptor | chr3 | GO:0051897 | Not Cancer Driver | No | 178 | 0.127 | 182 | 27 | 0.148 | 1 |
| MTDH | MTDH | Q86UE4 | Protein LYRIC | chr8 | GO:0051897 | Not Cancer Driver | No | 83 | 0.143 | 516 | 81 | 0.157 | 0 |
| MYDGF | MYDGF | Q969H8 | Myeloid-derived growth factor | chr19 | GO:0051897 | Not Cancer Driver | No | 23 | 0.133 | 26 | 4 | 0.154 | 0 |
| MYOC | MYOC | Q99972 | Myocilin | chr1 | GO:0051897 | Not Cancer Driver | No | 92 | 0.183 | 196 | 43 | 0.219 | 58 |
| MYORG | MYORG | Q6NSJ0 | Myogenesis-regulating glycosidase | chr9 | GO:0051897 | Not Cancer Driver | No | 88 | 0.123 | 60 | 3 | 0.05 | 2 |
| NOX4 | NOX4 | Q9NPH5 | NADPH oxidase 4 | chr11 | GO:0051897 | Not Cancer Driver | No | 123 | 0.213 | 0 | 0 | 0.0 | 0 |
| NRG1_ENST00000405005 | NRG1 | Q02297 | Pro-neuregulin-1, membrane-bound isoform | chr8 | GO:0051897 | Census, Compendium | Yes | 159 | 0.248 | 528 | 132 | 0.25 | 0 |
| NTS | NTS | P30990 | Neurotensin/neuromedin N | chr12 | GO:0051897 | Not Cancer Driver | No | 26 | 0.153 | 23 | 2 | 0.087 | 0 |
| OSBPL8 | OSBPL8 | Q9BZF1 | Oxysterol-binding protein-related protein 8 | chr12 | GO:0051897 | Not Cancer Driver | No | 105 | 0.118 | 401 | 37 | 0.092 | 0 |
| OSM | OSM | P13725 | Oncostatin-M | chr22 | GO:0051897 | Not Cancer Driver | No | 43 | 0.171 | 114 | 24 | 0.211 | 0 |
| P2RX4_ENST00000337233 | P2RX4 | Q99571 | P2X purinoceptor 4 | chr12 | GO:0051897 | Not Cancer Driver | No | 36 | 0.093 | 0 | 0 | 0.0 | 0 |
| P2RY12 | P2RY12 | Q9H244 | P2Y purinoceptor 12 | chr3 | GO:0051897 | Not Cancer Driver | No | 57 | 0.167 | 21 | 2 | 0.095 | 3 |
| PARK7_ENST00000377488 | PARK7 | Q99497 | Parkinson disease protein 7 | chr1 | GO:0051897 | Not Cancer Driver | No | 11 | 0.058 | 30 | 0 | 0.0 | 5 |
| PDGFA | PDGFA | P04085 | Platelet-derived growth factor subunit A | chr7 | GO:0051897 | Not Cancer Driver | No | 31 | 0.147 | 75 | 10 | 0.133 | 0 |
| PHB_ENST00000300408 | PHB1 | P35232 | Prohibitin 1 | chr17 | GO:0051897 | Not Cancer Driver | No | 37 | 0.136 | 4 | 1 | 0.25 | 0 |
| PIK3CA | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | GO:0051897 | Census, Compendium | Yes | 1669 | 1.563 | 38 | 11 | 0.289 | 30 |
| PIK3CB_ENST00000477593 | PIK3CB | P42338 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | chr3 | GO:0051897 | Census, Compendium | Yes | 150 | 0.14 | 42 | 4 | 0.095 | 0 |
| PIK3CD | PIK3CD | O00329 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | chr1 | GO:0051897 | Not Cancer Driver | No | 140 | 0.134 | 60 | 13 | 0.217 | 1 |
| PIK3CG | PIK3CG | P48736 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | chr7 | GO:0051897 | Not Cancer Driver | No | 318 | 0.289 | 121 | 39 | 0.322 | 0 |
| PIK3R5 | PIK3R5 | Q8WYR1 | Phosphoinositide 3-kinase regulatory subunit 5 | chr17 | GO:0051897 | Not Cancer Driver | No | 143 | 0.163 | 316 | 55 | 0.174 | 1 |
| PINK1 | PINK1 | Q9BXM7 | Serine/threonine-protein kinase PINK1, mitochondrial | chr1 | GO:0051897 | Not Cancer Driver | No | 57 | 0.098 | 99 | 13 | 0.131 | 23 |
| PTK2_ENST00000522684 | PTK2 | Q05397 | Focal adhesion kinase 1 | chr8 | GO:0051897 | Not Cancer Driver | No | 134 | 0.127 | 425 | 55 | 0.129 | 0 |
| PTPRJ | PTPRJ | Q12913 | Receptor-type tyrosine-protein phosphatase eta | chr11 | GO:0051897 | Not Cancer Driver | No | 184 | 0.138 | 401 | 61 | 0.152 | 0 |
| RAMP3 | RAMP3 | O60896 | Receptor activity-modifying protein 3 | chr7 | GO:0051897 | Not Cancer Driver | No | 30 | 0.203 | 0 | 0 | 0.0 | 0 |
| RASD2 | RASD2 | Q96D21 | GTP-binding protein Rhes | chr22 | GO:0051897 | Not Cancer Driver | No | 59 | 0.222 | 14 | 2 | 0.143 | 0 |
| RET | RET | P07949 | Proto-oncogene tyrosine-protein kinase receptor Ret | chr10 | GO:0051897 | Census, Compendium | Yes | 208 | 0.187 | 105 | 12 | 0.114 | 139 |
| RICTOR_ENST00000357387 | RICTOR | Q6R327 | Rapamycin-insensitive companion of mTOR | chr5 | GO:0051897 | Not Cancer Driver | No | 212 | 0.124 | 366 | 50 | 0.137 | 0 |
| RTN4 | RTN4 | Q9NQC3 | Reticulon-4 | chr2 | GO:0051897 | Not Cancer Driver | No | 121 | 0.102 | 866 | 82 | 0.095 | 0 |
| SEMA5A | SEMA5A | Q13591 | Semaphorin-5A | chr5 | GO:0051897 | Not Cancer Driver | No | 266 | 0.248 | 23 | 4 | 0.174 | 0 |
| SPRY2 | SPRY2 | O43597 | Protein sprouty homolog 2 | chr13 | GO:0051897 | Not Cancer Driver | No | 46 | 0.146 | 169 | 29 | 0.172 | 1 |
| SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0051897 | Census | Yes | 53 | 0.099 | 130 | 11 | 0.085 | 1 |
| STK3_ENST00000419617 | STK3 | Q13188 | Serine/threonine-protein kinase 3 | chr8 | GO:0051897 | Not Cancer Driver | No | 70 | 0.143 | 241 | 32 | 0.133 | 0 |
| STOX1_ENST00000399169 | STOX1 | Q6ZVD7 | Storkhead-box protein 1 | chr10 | GO:0051897 | Not Cancer Driver | No | 121 | 0.122 | 659 | 83 | 0.126 | 2 |
| TCF7L2_ENST00000355995 | TCF7L2 | Q9NQB0 | Transcription factor 7-like 2 | chr10 | GO:0051897 | Census, Compendium | Yes | 122 | 0.197 | 516 | 93 | 0.18 | 0 |
| TEK | TEK | Q02763 | Angiopoietin-1 receptor | chr9 | GO:0051897 | Not Cancer Driver | No | 219 | 0.195 | 126 | 22 | 0.175 | 10 |
| TGFB1 | TGFB1 | P01137 | Transforming growth factor beta-1 proprotein | chr19 | GO:0051897 | Not Cancer Driver | No | 41 | 0.105 | 41 | 4 | 0.098 | 10 |
| TGFBR1_ENST00000374994 | TGFBR1 | P36897 | TGF-beta receptor type-1 | chr9 | GO:0051897 | Not Cancer Driver | No | 86 | 0.171 | 23 | 3 | 0.13 | 15 |
| THBS1 | THBS1 | P07996 | Thrombospondin-1 | chr15 | GO:0051897 | Not Cancer Driver | No | 188 | 0.161 | 320 | 58 | 0.181 | 0 |
| THPO | THPO | P40225 | Thrombopoietin | chr3 | GO:0051897 | Not Cancer Driver | No | 63 | 0.178 | 163 | 25 | 0.153 | 0 |
| TNF | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0051897 | Not Cancer Driver | No | 24 | 0.103 | 45 | 3 | 0.067 | 0 |
| TNFAIP8L3 | TNFAIP8L3 | Q5GJ75 | Tumor necrosis factor alpha-induced protein 8-like protein 3 | chr15 | GO:0051897 | Not Cancer Driver | No | 40 | 0.137 | 111 | 12 | 0.108 | 0 |
| TNFSF11 | TNFSF11 | O14788 | Tumor necrosis factor ligand superfamily member 11 | chr13 | GO:0051897 | Not Cancer Driver | No | 52 | 0.164 | 56 | 1 | 0.018 | 1 |
| TPBG_ENST00000543496 | TPBG | Q13641 | Trophoblast glycoprotein | chr6 | GO:0051897 | Not Cancer Driver | No | 58 | 0.138 | 13 | 1 | 0.077 | 0 |
| TSPYL5 | TSPYL5 | Q86VY4 | Testis-specific Y-encoded-like protein 5 | chr8 | GO:0051897 | Not Cancer Driver | No | 92 | 0.221 | 257 | 61 | 0.237 | 0 |
| TXN | TXN | P10599 | Thioredoxin | chr9 | GO:0051897 | Not Cancer Driver | No | 6 | 0.057 | 0 | 0 | 0.0 | 0 |