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Total number of protein in "GO:0051640" GO term:  278

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACTN4 ACTN4 O43707 Alpha-actinin-4 chr19 GO:0051640 Not Cancer Driver No 131 0.144 244 42 0.172 8
ACTR10 ACTR10 Q9NZ32 Actin-related protein 10 chr14 GO:0051640 Not Cancer Driver No 45 0.108 29 3 0.103 0
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 GO:0051640 Not Cancer Driver No 51 0.129 6 2 0.333 0
ACTR3 ACTR3 P61158 Actin-related protein 3 chr2 GO:0051640 Not Cancer Driver No 32 0.077 16 2 0.125 0
AGBL4 AGBL4 Q5VU57 Cytosolic carboxypeptidase 6 chr1 GO:0051640 Not Cancer Driver No 65 0.129 72 2 0.028 0
AGTPBP1_ENST00000357081 AGTPBP1 Q9UPW5 Cytosolic carboxypeptidase 1 chr9 GO:0051640 Not Cancer Driver No 158 0.129 321 42 0.131 4
AHCYL1 AHCYL1 O43865 S-adenosylhomocysteine hydrolase-like protein 1 chr1 GO:0051640 Not Cancer Driver No 58 0.109 108 10 0.093 0
ALB ALB P02768 Albumin chr4 GO:0051640 Compendium Yes 162 0.266 6 0 0.0 3
AP3B1 AP3B1 O00203 AP-3 complex subunit beta-1 chr5 GO:0051640 Not Cancer Driver No 126 0.115 316 31 0.098 1
AP3B2_ENST00000261722 AP3B2 Q13367 AP-3 complex subunit beta-2 chr15 GO:0051640 Not Cancer Driver No 145 0.134 381 51 0.134 0
AP3D1_ENST00000345016 AP3D1 O14617 AP-3 complex subunit delta-1 chr19 GO:0051640 Not Cancer Driver No 138 0.12 404 59 0.146 0
AP3M1 AP3M1 Q9Y2T2 AP-3 complex subunit mu-1 chr10 GO:0051640 Not Cancer Driver No 45 0.108 19 1 0.053 0
AP3M2_ENST00000174653 AP3M2 P53677 AP-3 complex subunit mu-2 chr8 GO:0051640 Not Cancer Driver No 56 0.134 55 3 0.055 0
AP3S1 AP3S1 Q92572 AP-3 complex subunit sigma-1 chr5 GO:0051640 Not Cancer Driver No 35 0.181 0 0 0.0 0
AP3S2 AP3S2 P59780 AP-3 complex subunit sigma-2 chr15 GO:0051640 Not Cancer Driver No 21 0.109 0 0 0.0 0
ARCN1 ARCN1 P48444 Coatomer subunit delta chr11 GO:0051640 Not Cancer Driver No 46 0.09 194 24 0.124 0
ARHGAP21 ARHGAP21 Q5T5U3 Rho GTPase-activating protein 21 chr10 GO:0051640 Not Cancer Driver No 242 0.124 1612 204 0.127 0
ARL6 ARL6 Q9H0F7 ADP-ribosylation factor-like protein 6 chr3 GO:0051640 Not Cancer Driver No 29 0.156 4 0 0.0 6
ARMC1 ARMC1 Q9NVT9 Armadillo repeat-containing protein 1 chr8 GO:0051640 Not Cancer Driver No 34 0.121 110 11 0.1 0
ARMCX3_ENST00000537169 ARMCX3 Q9UH62 Armadillo repeat-containing X-linked protein 3 chrX GO:0051640 Not Cancer Driver No 39 0.103 77 7 0.091 0
ASIP_ENST00000374954 ASIP P42127 Agouti-signaling protein chr20 GO:0051640 Not Cancer Driver No 16 0.121 36 9 0.25 0
ATG14 ATG14 Q6ZNE5 Beclin 1-associated autophagy-related key regulator chr14 GO:0051640 Not Cancer Driver No 48 0.098 209 24 0.115 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0051640 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATP2A1 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 GO:0051640 Not Cancer Driver No 157 0.157 80 11 0.138 1
ATP2A2 ATP2A2 P16615 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 chr12 GO:0051640 Not Cancer Driver No 136 0.131 78 14 0.179 41
BBS2 BBS2 Q9BXC9 Bardet-Biedl syndrome 2 protein chr16 GO:0051640 Not Cancer Driver No 90 0.125 76 16 0.211 20
BBS4 BBS4 Q96RK4 Bardet-Biedl syndrome 4 protein chr15 GO:0051640 Not Cancer Driver No 58 0.112 110 16 0.145 9
BBS5 BBS5 Q8N3I7 Bardet-Biedl syndrome 5 protein chr2 GO:0051640 Not Cancer Driver No 39 0.114 20 1 0.05 2
BBS7 BBS7 Q8IWZ6 Bardet-Biedl syndrome 7 protein chr4 GO:0051640 Not Cancer Driver No 99 0.138 56 8 0.143 4
BHLHA15 BHLHA15 Q7RTS1 Class A basic helix-loop-helix protein 15 chr7 GO:0051640 Not Cancer Driver No 12 0.063 183 12 0.066 0
BICD1 BICD1 Q96G01 Protein bicaudal D homolog 1 chr12 GO:0051640 Not Cancer Driver No 124 0.127 656 86 0.131 0
BICD2_ENST00000375512 BICD2 Q8TD16 Protein bicaudal D homolog 2 chr9 GO:0051640 Not Cancer Driver No 115 0.14 546 73 0.134 10
BLOC1S1 BLOC1S1 P78537 Biogenesis of lysosome-related organelles complex 1 subunit 1 chr12 GO:0051640 Not Cancer Driver No 12 0.078 76 2 0.026 0
BLOC1S2 BLOC1S2 Q6QNY1 Biogenesis of lysosome-related organelles complex 1 subunit 2 chr10 GO:0051640 Not Cancer Driver No 17 0.12 34 6 0.176 0
BLOC1S3 BLOC1S3 Q6QNY0 Biogenesis of lysosome-related organelles complex 1 subunit 3 chr19 GO:0051640 Not Cancer Driver No 3 0.015 148 2 0.014 0
BLOC1S4 BLOC1S4 Q9NUP1 Biogenesis of lysosome-related organelles complex 1 subunit 4 chr4 GO:0051640 Not Cancer Driver No 11 0.051 102 1 0.01 0
BLOC1S5 BLOC1S5 Q8TDH9 Biogenesis of lysosome-related organelles complex 1 subunit 5 chr6 GO:0051640 Not Cancer Driver No 15 0.08 153 13 0.085 0
BLOC1S6_ENST00000220531 BLOC1S6 Q9UL45 Biogenesis of lysosome-related organelles complex 1 subunit 6 chr15 GO:0051640 Not Cancer Driver No 12 0.07 111 11 0.099 0
BRAT1 BRAT1 Q6PJG6 BRCA1-associated ATM activator 1 chr7 GO:0051640 Not Cancer Driver No 112 0.136 101 13 0.129 0
BVES BVES Q8NE79 Blood vessel epicardial substance chr6 GO:0051640 Not Cancer Driver No 59 0.164 65 15 0.231 1
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 GO:0051640 Not Cancer Driver No 19 0.128 115 15 0.13 7
CAV2 CAV2 P51636 Caveolin-2 chr7 GO:0051640 Not Cancer Driver No 20 0.123 5 2 0.4 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0051640 Census, Compendium Yes 115 0.127 512 56 0.109 4
CCDC155 KASH5 Q8N6L0 Protein KASH5 chr19 GO:0051640 Not Cancer Driver No 88 0.157 401 70 0.175 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0051640 Not Cancer Driver No 39 0.204 23 2 0.087 1
CENPE CENPE Q02224 Centromere-associated protein E chr4 GO:0051640 Not Cancer Driver No 343 0.127 1620 228 0.141 2
CEP120 CEP120 Q8N960 Centrosomal protein of 120 kDa chr5 GO:0051640 Not Cancer Driver No 102 0.103 448 52 0.116 1
CEP290 CEP290 O15078 Centrosomal protein of 290 kDa chr12 GO:0051640 Not Cancer Driver No 255 0.103 1421 152 0.107 3
CEP83_ENST00000339839 CEP83 Q9Y592 Centrosomal protein of 83 kDa chr12 GO:0051640 Not Cancer Driver No 90 0.128 488 59 0.121 2
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 GO:0051640 Not Cancer Driver No 287 0.194 145 18 0.124 151
CHGA CHGA P10645 Chromogranin-A chr14 GO:0051640 Not Cancer Driver No 46 0.101 421 44 0.105 0
CLN3_ENST00000636147 CLN3 Q13286 Battenin chr16 GO:0051640 Not Cancer Driver No 58 0.132 69 10 0.145 9
CLNK CLNK Q7Z7G1 Cytokine-dependent hematopoietic cell linker chr4 GO:0051640 Not Cancer Driver No 85 0.199 320 73 0.228 0
CLUH_ENST00000435359 CLUH O75153 Clustered mitochondria protein homolog chr17 GO:0051640 Not Cancer Driver No 164 0.125 339 48 0.142 0
COPG1 COPG1 Q9Y678 Coatomer subunit gamma-1 chr3 GO:0051640 Not Cancer Driver No 108 0.124 107 13 0.121 0
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 GO:0051640 Not Cancer Driver No 36 0.108 32 7 0.219 0
CPLX2_ENST00000515094 CPLX2 Q6PUV4 Complexin-2 chr5 GO:0051640 Not Cancer Driver No 27 0.201 134 27 0.201 0
CTBP2_ENST00000494626 CTBP2 P56545 C-terminal-binding protein 2 chr10 GO:0051640 Not Cancer Driver No 48 0.108 94 4 0.043 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0051640 Census, Compendium Yes 415 0.531 288 301 1.045 14
DAB1_ENST00000371231 DAB1 O75553 Disabled homolog 1 chr1 GO:0051640 Not Cancer Driver No 200 0.34 393 143 0.364 0
DCTN2_ENST00000548249 DCTN2 Q13561 Dynactin subunit 2 chr12 GO:0051640 Not Cancer Driver No 46 0.115 253 32 0.126 0
DLG1_ENST00000419354 DLG1 Q12959 Disks large homolog 1 chr3 GO:0051640 Not Cancer Driver No 120 0.133 460 67 0.146 0
DLGAP5 DLGAP5 Q15398 Disks large-associated protein 5 chr14 GO:0051640 Not Cancer Driver No 84 0.099 676 70 0.104 0
DNM1L_ENST00000549701 DNM1L O00429 Dynamin-1-like protein chr12 GO:0051640 Not Cancer Driver No 67 0.091 212 23 0.108 7
DOCK7_ENST00000635253 DOCK7 Q96N67 Dedicator of cytokinesis protein 7 chr1 GO:0051640 Not Cancer Driver No 262 0.122 454 53 0.117 0
DTNBP1 DTNBP1 Q96EV8 Dysbindin chr6 GO:0051640 Not Cancer Driver No 49 0.14 210 25 0.119 0
DYNC1H1 DYNC1H1 Q14204 Cytoplasmic dynein 1 heavy chain 1 chr14 GO:0051640 Not Cancer Driver No 505 0.109 495 62 0.125 21
ESYT1_ENST00000394048 ESYT1 Q9BSJ8 Extended synaptotagmin-1 chr12 GO:0051640 Not Cancer Driver No 126 0.114 278 32 0.115 0
ESYT2_ENST00000613624 ESYT2 A0FGR8 Extended synaptotagmin-2 chr7 GO:0051640 Not Cancer Driver No 94 0.102 376 25 0.066 0
ESYT3 ESYT3 A0FGR9 Extended synaptotagmin-3 chr3 GO:0051640 Not Cancer Driver No 115 0.13 179 18 0.101 0
EZR EZR P15311 Ezrin chr6 GO:0051640 Census Yes 66 0.113 295 35 0.119 0
FEZ1 FEZ1 Q99689 Fasciculation and elongation protein zeta-1 chr11 GO:0051640 Not Cancer Driver No 66 0.168 277 49 0.177 0
FHOD1 FHOD1 Q9Y613 FH1/FH2 domain-containing protein 1 chr16 GO:0051640 Not Cancer Driver No 151 0.13 575 82 0.143 0
FMN2 FMN2 Q9NZ56 Formin-2 chr1 GO:0051640 Not Cancer Driver No 614 0.357 1322 475 0.359 0
FNBP1L FNBP1L Q5T0N5 Formin-binding protein 1-like chr1 GO:0051640 Not Cancer Driver No 56 0.093 371 30 0.081 0
FYCO1 FYCO1 Q9BQS8 FYVE and coiled-coil domain-containing protein 1 chr3 GO:0051640 Not Cancer Driver No 181 0.122 892 106 0.119 1
GPR143 GPR143 P51810 G-protein coupled receptor 143 chrX GO:0051640 Not Cancer Driver No 47 0.116 83 14 0.169 34
GRAMD2A GRAMD2A Q8IUY3 GRAM domain-containing protein 2A chr15 GO:0051640 Not Cancer Driver No 49 0.138 106 8 0.075 0
HAP1_ENST00000310778 HAP1 P54257 Huntingtin-associated protein 1 chr17 GO:0051640 Not Cancer Driver No 97 0.145 454 60 0.132 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX GO:0051640 Not Cancer Driver No 178 0.147 409 59 0.144 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0051640 Census Yes 118 0.143 435 51 0.117 0
HOOK3 HOOK3 Q86VS8 Protein Hook homolog 3 chr8 GO:0051640 Census Yes 79 0.11 493 55 0.112 0
HSBP1_ENST00000570259 HSBP1 O75506 Heat shock factor-binding protein 1 chr16 GO:0051640 Not Cancer Driver No 6 0.079 76 6 0.079 0
IFFO1_ENST00000396840 IFFO1 Q0D2I5 Non-homologous end joining factor IFFO1 chr12 GO:0051640 Not Cancer Driver No 59 0.106 363 33 0.091 0
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 GO:0051640 Not Cancer Driver No 254 0.246 97 27 0.278 0
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 GO:0051640 Not Cancer Driver No 88 0.105 251 17 0.068 0
KATNB1 KATNB1 Q9BVA0 Katanin p80 WD40 repeat-containing subunit B1 chr16 GO:0051640 Not Cancer Driver No 70 0.107 179 24 0.134 3
KCNB1_ENST00000635465 KCNB1 Q14721 Potassium voltage-gated channel subfamily B member 1 chr20 GO:0051640 Not Cancer Driver No 192 0.224 417 100 0.24 6
KIF13A KIF13A Q9H1H9 Kinesin-like protein KIF13A chr6 GO:0051640 Not Cancer Driver No 220 0.122 816 103 0.126 0
KIF1A_ENST00000320389 KIF1A Q12756 Kinesin-like protein KIF1A chr2 GO:0051640 Not Cancer Driver No 275 0.163 594 79 0.133 35
KIF1C KIF1C O43896 Kinesin-like protein KIF1C chr17 GO:0051640 Not Cancer Driver No 131 0.119 695 94 0.135 1
KIF3A_ENST00000378746 KIF3A Q9Y496 Kinesin-like protein KIF3A chr5 GO:0051640 Not Cancer Driver No 92 0.132 409 59 0.144 0
KIF3B KIF3B O15066 Kinesin-like protein KIF3B chr20 GO:0051640 Not Cancer Driver No 105 0.141 485 69 0.142 2
KIF5A KIF5A Q12840 Kinesin heavy chain isoform 5A chr12 GO:0051640 Not Cancer Driver No 194 0.188 569 103 0.181 14
KIF5B KIF5B P33176 Kinesin-1 heavy chain chr10 GO:0051640 Census, Compendium Yes 122 0.127 586 67 0.114 0
KIFAP3 KIFAP3 Q92845 Kinesin-associated protein 3 chr1 GO:0051640 Not Cancer Driver No 116 0.146 71 10 0.141 0
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0051640 Census, Compendium Yes 226 0.232 83 33 0.398 21
KPNB1 KPNB1 Q14974 Importin subunit beta-1 chr17 GO:0051640 Not Cancer Driver No 92 0.105 94 11 0.117 0
LAT2 LAT2 Q9GZY6 Linker for activation of T-cells family member 2 chr7 GO:0051640 Not Cancer Driver No 39 0.16 176 29 0.165 0
LAT_ENST00000360872 LAT O43561 Linker for activation of T-cells family member 1 chr16 GO:0051640 Not Cancer Driver No 37 0.141 213 29 0.136 0
LMNA LMNA P02545 Prelamin-A/C chr1 GO:0051640 Census Yes 68 0.102 544 49 0.09 131
LRPPRC LRPPRC P42704 Leucine-rich PPR motif-containing protein, mitochondrial chr2 GO:0051640 Not Cancer Driver No 131 0.094 18 2 0.111 1
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0051640 Not Cancer Driver No 519 0.205 90 17 0.189 23
LTV1 LTV1 Q96GA3 Protein LTV1 homolog chr6 GO:0051640 Not Cancer Driver No 45 0.095 388 30 0.077 0
MAD2L1 MAD2L1 Q13257 Mitotic spindle assembly checkpoint protein MAD2A chr4 GO:0051640 Not Cancer Driver No 26 0.127 12 1 0.083 0
MAJIN_ENST00000530444 MAJIN Q3KP22 Membrane-anchored junction protein chr11 GO:0051640 Not Cancer Driver No 17 0.097 143 15 0.105 0
MAP1B MAP1B P46821 Microtubule-associated protein 1B chr5 GO:0051640 Not Cancer Driver No 332 0.135 1947 278 0.143 0
MAP1S MAP1S Q66K74 Microtubule-associated protein 1S chr19 GO:0051640 Not Cancer Driver No 118 0.111 527 48 0.091 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0051640 Not Cancer Driver No 128 0.169 750 126 0.168 18
MARK1_ENST00000366917 MARK1 Q9P0L2 Serine/threonine-protein kinase MARK1 chr1 GO:0051640 Not Cancer Driver No 161 0.203 454 108 0.238 0
MARK2 MARK2 Q7KZI7 Serine/threonine-protein kinase MARK2 chr11 GO:0051640 Compendium Yes 124 0.157 445 70 0.157 0
MFN1 MFN1 Q8IWA4 Mitofusin-1 chr3 GO:0051640 Not Cancer Driver No 90 0.121 64 5 0.078 0
MFN2_ENST00000444836 MFN2 O95140 Mitofusin-2 chr1 GO:0051640 Not Cancer Driver No 80 0.106 81 9 0.111 20
MGARP MGARP Q8TDB4 Protein MGARP chr4 GO:0051640 Not Cancer Driver No 25 0.104 207 22 0.106 0
MILR1 MILR1 Q7Z6M3 Allergin-1 chr17 GO:0051640 Not Cancer Driver No 11 0.032 60 4 0.067 0
MISP MISP Q8IVT2 Mitotic interactor and substrate of PLK1 chr19 GO:0051640 Not Cancer Driver No 138 0.203 646 132 0.204 0
MKKS MKKS Q9NPJ1 McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin chr20 GO:0051640 Not Cancer Driver No 56 0.098 6 1 0.167 22
MLH1 MLH1 P40692 DNA mismatch repair protein Mlh1 chr3 GO:0051640 Census Yes 92 0.122 208 22 0.106 85
MLPH MLPH Q9BV36 Melanophilin chr2 GO:0051640 Not Cancer Driver No 78 0.13 463 57 0.123 1
MOS MOS P00540 Proto-oncogene serine/threonine-protein kinase mos chr8 GO:0051640 Not Cancer Driver No 94 0.272 16 4 0.25 0
MOSPD3_ENST00000223054 MOSPD3 O75425 Motile sperm domain-containing protein 3 chr7 GO:0051640 Not Cancer Driver No 30 0.128 77 9 0.117 0
MREG MREG Q8N565 Melanoregulin chr2 GO:0051640 Not Cancer Driver No 21 0.098 24 2 0.083 0
MRGPRX2 MRGPRX2 Q96LB1 Mas-related G-protein coupled receptor member X2 chr11 GO:0051640 Not Cancer Driver No 86 0.261 11 2 0.182 0
MUL1 MUL1 Q969V5 Mitochondrial ubiquitin ligase activator of NFKB 1 chr1 GO:0051640 Not Cancer Driver No 48 0.136 16 2 0.125 0
MYH9 MYH9 P35579 Myosin-9 chr22 GO:0051640 Census, Compendium Yes 310 0.158 1120 160 0.143 17
MYO15A_ENST00000647165 MYO15A Q9UKN7 Unconventional myosin-XV chr17 GO:0051640 Not Cancer Driver No 471 0.133 1386 172 0.124 4
MYO1A MYO1A Q9UBC5 Unconventional myosin-Ia chr12 GO:0051640 Not Cancer Driver No 170 0.163 57 5 0.088 0
MYO1B MYO1B O43795 Unconventional myosin-Ib chr2 GO:0051640 Not Cancer Driver No 144 0.127 34 4 0.118 0
MYO1C MYO1C O00159 Unconventional myosin-Ic chr17 GO:0051640 Not Cancer Driver No 110 0.103 66 11 0.167 0
MYO1D MYO1D O94832 Unconventional myosin-Id chr17 GO:0051640 Not Cancer Driver No 126 0.125 61 6 0.098 0
MYO1E MYO1E Q12965 Unconventional myosin-Ie chr15 GO:0051640 Not Cancer Driver No 137 0.124 229 14 0.061 1
MYO1F MYO1F O00160 Unconventional myosin-If chr19 GO:0051640 Not Cancer Driver No 209 0.19 246 48 0.195 0
MYO1G MYO1G B0I1T2 Unconventional myosin-Ig chr7 GO:0051640 Not Cancer Driver No 125 0.123 117 12 0.103 0
MYO1H MYO1H Q8N1T3 Unconventional myosin-Ih chr12 GO:0051640 Not Cancer Driver No 154 0.149 8 2 0.25 0
MYO5A MYO5A Q9Y4I1 Unconventional myosin-Va chr15 GO:0051640 Census, Compendium Yes 224 0.121 497 58 0.117 0
MYO5B MYO5B Q9ULV0 Unconventional myosin-Vb chr18 GO:0051640 Not Cancer Driver No 269 0.146 505 68 0.135 14
MYO5C MYO5C Q9NQX4 Unconventional myosin-Vc chr15 GO:0051640 Not Cancer Driver No 204 0.117 394 43 0.109 0
MYO6 MYO6 Q9UM54 Unconventional myosin-VI chr6 GO:0051640 Not Cancer Driver No 176 0.136 342 41 0.12 3
MYO7A MYO7A Q13402 Unconventional myosin-VIIa chr11 GO:0051640 Not Cancer Driver No 298 0.135 369 58 0.157 50
MYO7B_ENST00000409816 MYO7B Q6PIF6 Unconventional myosin-VIIb chr2 GO:0051640 Not Cancer Driver No 375 0.177 216 41 0.19 0
NDRG4_ENST00000570248 NDRG4 Q9ULP0 Protein NDRG4 chr16 GO:0051640 Not Cancer Driver No 44 0.125 90 11 0.122 0
NECTIN2 NECTIN2 Q92692 Nectin-2 chr19 GO:0051640 Not Cancer Driver No 63 0.117 296 29 0.098 0
NEFL NEFL P07196 Neurofilament light polypeptide chr8 GO:0051640 Not Cancer Driver No 92 0.169 285 39 0.137 12
NLGN1_ENST00000361589 NLGN1 Q8N2Q7 Neuroligin-1 chr3 GO:0051640 Not Cancer Driver No 214 0.248 248 61 0.246 4
NMD3_ENST00000351193 NMD3 Q96D46 60S ribosomal export protein NMD3 chr3 GO:0051640 Not Cancer Driver No 67 0.133 104 20 0.192 0
NOP9 NOP9 Q86U38 Nucleolar protein 9 chr14 GO:0051640 Not Cancer Driver No 53 0.083 166 14 0.084 0
NPM1 NPM1 P06748 Nucleophosmin chr5 GO:0051640 Census, Compendium Yes 29 0.099 249 22 0.088 0
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:0051640 Census Yes 83 0.133 298 37 0.124 0
NUP88 NUP88 Q99567 Nuclear pore complex protein Nup88 chr17 GO:0051640 Not Cancer Driver No 86 0.116 147 25 0.17 1
OPA1_ENST00000392438 OPA1 O60313 Dynamin-like 120 kDa protein, mitochondrial chr3 GO:0051640 Not Cancer Driver No 114 0.119 131 17 0.13 60
PACS2_ENST00000325438 PACS2 Q86VP3 Phosphofurin acidic cluster sorting protein 2 chr14 GO:0051640 Not Cancer Driver No 122 0.137 460 59 0.128 1
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:0051640 Not Cancer Driver No 42 0.102 82 11 0.134 7
PARD3 PARD3 Q8TEW0 Partitioning defective 3 homolog chr10 GO:0051640 Not Cancer Driver No 200 0.147 1144 170 0.149 2
PARD3B PARD3B Q8TEW8 Partitioning defective 3 homolog B chr2 GO:0051640 Not Cancer Driver No 241 0.2 977 203 0.208 0
PCLO PCLO Q9Y6V0 Protein piccolo chr7 GO:0051640 Not Cancer Driver No 1611 0.313 4237 1301 0.307 0
PCM1 PCM1 Q15154 Pericentriolar material 1 protein chr8 GO:0051640 Census Yes 152 0.075 1665 134 0.08 0
PDCD10_ENST00000473645 PDCD10 Q9BUL8 Programmed cell death protein 10 chr3 GO:0051640 Not Cancer Driver No 32 0.151 25 4 0.16 0
PDZD8 PDZD8 Q8NEN9 PDZ domain-containing protein 8 chr10 GO:0051640 Not Cancer Driver No 126 0.109 484 65 0.134 0
PEX1 PEX1 O43933 Peroxisome biogenesis factor 1 chr7 GO:0051640 Not Cancer Driver No 143 0.111 304 36 0.118 14
PEX13 PEX13 Q92968 Peroxisomal membrane protein PEX13 chr2 GO:0051640 Not Cancer Driver No 38 0.094 133 14 0.105 1
PEX14 PEX14 O75381 Peroxisomal membrane protein PEX14 chr1 GO:0051640 Not Cancer Driver No 38 0.101 266 28 0.105 0
PIK3CD PIK3CD O00329 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform chr1 GO:0051640 Not Cancer Driver No 140 0.134 60 13 0.217 1
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 GO:0051640 Not Cancer Driver No 318 0.289 121 39 0.322 0
PKHD1 PKHD1 P08F94 Fibrocystin chr6 GO:0051640 Not Cancer Driver No 778 0.191 413 81 0.196 93
PLA2G3 PLA2G3 Q9NZ20 Group 3 secretory phospholipase A2 chr22 GO:0051640 Not Cancer Driver No 115 0.226 175 39 0.223 0
PLEK PLEK P08567 Pleckstrin chr2 GO:0051640 Not Cancer Driver No 81 0.231 39 9 0.231 0
PLIN5 PLIN5 Q00G26 Perilipin-5 chr19 GO:0051640 Not Cancer Driver No 49 0.106 192 21 0.109 0
PPFIA2 PPFIA2 O75334 Liprin-alpha-2 chr12 GO:0051640 Not Cancer Driver No 342 0.272 936 263 0.281 0
PPFIA3 PPFIA3 O75145 Liprin-alpha-3 chr19 GO:0051640 Not Cancer Driver No 140 0.117 831 107 0.129 0
PSEN2 PSEN2 P49810 Presenilin-2 chr1 GO:0051640 Not Cancer Driver No 68 0.152 89 16 0.18 7
PTGDR PTGDR Q13258 Prostaglandin D2 receptor chr14 GO:0051640 Not Cancer Driver No 74 0.206 14 9 0.643 0
PTGDS PTGDS P41222 Prostaglandin-H2 D-isomerase chr9 GO:0051640 Not Cancer Driver No 31 0.163 13 3 0.231 0
RAB10 RAB10 P61026 Ras-related protein Rab-10 chr2 GO:0051640 Not Cancer Driver No 19 0.095 28 2 0.071 0
RAB11A RAB11A P62491 Ras-related protein Rab-11A chr15 GO:0051640 Not Cancer Driver No 31 0.144 43 4 0.093 0
RAB11B RAB11B Q15907 Ras-related protein Rab-11B chr19 GO:0051640 Not Cancer Driver No 26 0.119 39 3 0.077 2
RAB12 RAB12 Q6IQ22 Ras-related protein Rab-12 chr18 GO:0051640 Not Cancer Driver No 22 0.09 72 3 0.042 0
RAB13 RAB13 P51153 Ras-related protein Rab-13 chr1 GO:0051640 Not Cancer Driver No 19 0.094 40 0 0.0 0
RAB15 RAB15 P59190 Ras-related protein Rab-15 chr14 GO:0051640 Not Cancer Driver No 18 0.085 50 5 0.1 0
RAB17 RAB17 Q9H0T7 Ras-related protein Rab-17 chr2 GO:0051640 Not Cancer Driver No 29 0.137 43 4 0.093 0
RAB1A RAB1A P62820 Ras-related protein Rab-1A chr2 GO:0051640 Not Cancer Driver No 16 0.078 38 2 0.053 0
RAB27A_ENST00000336787 RAB27A P51159 Ras-related protein Rab-27A chr15 GO:0051640 Not Cancer Driver No 25 0.113 15 4 0.267 3
RAB27B RAB27B O00194 Ras-related protein Rab-27B chr18 GO:0051640 Not Cancer Driver No 42 0.193 43 9 0.209 0
RAB3A RAB3A P20336 Ras-related protein Rab-3A chr19 GO:0051640 Not Cancer Driver No 25 0.114 43 4 0.093 0
RAB3B RAB3B P20337 Ras-related protein Rab-3B chr1 GO:0051640 Not Cancer Driver No 36 0.164 25 6 0.24 0
RAB3C RAB3C Q96E17 Ras-related protein Rab-3C chr5 GO:0051640 Not Cancer Driver No 52 0.229 54 10 0.185 0
RAB3D_ENST00000589655 RAB3D O95716 Ras-related protein Rab-3D chr19 GO:0051640 Not Cancer Driver No 37 0.169 46 6 0.13 0
RAB3IP RAB3IP Q96QF0 Rab-3A-interacting protein chr12 GO:0051640 Not Cancer Driver No 85 0.179 227 33 0.145 0
RAB6A_ENST00000336083 RAB6A P20340 Ras-related protein Rab-6A chr11 GO:0051640 Not Cancer Driver No 22 0.106 45 6 0.133 0
RAB8A RAB8A P61006 Ras-related protein Rab-8A chr19 GO:0051640 Not Cancer Driver No 37 0.179 26 3 0.115 0
RAB8B RAB8B Q92930 Ras-related protein Rab-8B chr15 GO:0051640 Not Cancer Driver No 22 0.106 29 2 0.069 0
RABEPK RABEPK Q7Z6M1 Rab9 effector protein with kelch motifs chr9 GO:0051640 Not Cancer Driver No 54 0.145 161 24 0.149 0
RAN_ENST00000392369 RAN P62826 GTP-binding nuclear protein Ran chr12 GO:0051640 Not Cancer Driver No 20 0.093 14 1 0.071 0
RASGRP1 RASGRP1 O95267 RAS guanyl-releasing protein 1 chr15 GO:0051640 Not Cancer Driver No 96 0.12 191 12 0.063 1
RHOT1_ENST00000333942 RHOT1 Q8IXI2 Mitochondrial Rho GTPase 1 chr17 GO:0051640 Not Cancer Driver No 56 0.091 46 2 0.043 0
RHOT2 RHOT2 Q8IXI1 Mitochondrial Rho GTPase 2 chr16 GO:0051640 Not Cancer Driver No 52 0.084 79 5 0.063 0
RIPOR1_ENST00000379312 RIPOR1 Q6ZS17 Rho family-interacting cell polarization regulator 1 chr16 GO:0051640 Not Cancer Driver No 125 0.102 687 71 0.103 0
RPS15_ENST00000592588 RPS15 P62841 40S ribosomal protein S15 chr19 GO:0051640 Not Cancer Driver No 13 0.09 59 7 0.119 0
RRS1 RRS1 Q15050 Ribosome biogenesis regulatory protein homolog chr8 GO:0051640 Not Cancer Driver No 23 0.063 315 18 0.057 0
S100A13_ENST00000392622 S100A13 Q99584 Protein S100-A13 chr1 GO:0051640 Not Cancer Driver No 12 0.122 6 0 0.0 0
SCFD2 SCFD2 Q8WU76 Sec1 family domain-containing protein 2 chr4 GO:0051640 Not Cancer Driver No 96 0.14 24 4 0.167 0
SDAD1 SDAD1 Q9NVU7 Protein SDA1 homolog chr4 GO:0051640 Not Cancer Driver No 65 0.095 288 29 0.101 0
SHROOM2 SHROOM2 Q13796 Protein Shroom2 chrX GO:0051640 Not Cancer Driver No 215 0.133 1381 188 0.136 0
SLC9A3R1 SLC9A3R1 O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 chr17 GO:0051640 Not Cancer Driver No 19 0.053 318 16 0.05 4
SNAP25 SNAP25 P60880 Synaptosomal-associated protein 25 chr20 GO:0051640 Not Cancer Driver No 61 0.296 176 49 0.278 1
SNAP29 SNAP29 O95721 Synaptosomal-associated protein 29 chr22 GO:0051640 Not Cancer Driver No 21 0.081 246 20 0.081 0
SNAPIN SNAPIN O95295 SNARE-associated protein Snapin chr1 GO:0051640 Not Cancer Driver No 9 0.066 62 5 0.081 0
SNPH_ENST00000381873 SNPH O15079 Syntaphilin chr20 GO:0051640 Not Cancer Driver No 79 0.16 406 71 0.175 0
SPAST SPAST Q9UBP0 Spastin chr2 GO:0051640 Not Cancer Driver No 73 0.119 270 25 0.093 77
SPIRE1 SPIRE1 Q08AE8 Protein spire homolog 1 chr18 GO:0051640 Not Cancer Driver No 78 0.103 414 48 0.116 0
SPIRE2 SPIRE2 Q8WWL2 Protein spire homolog 2 chr16 GO:0051640 Not Cancer Driver No 79 0.111 344 43 0.125 0
SPO11 SPO11 Q9Y5K1 Meiotic recombination protein SPO11 chr20 GO:0051640 Not Cancer Driver No 59 0.149 26 5 0.192 0
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:0051640 Census, Compendium Yes 75 0.173 135 14 0.104 9
STK25 STK25 O00506 Serine/threonine-protein kinase 25 chr2 GO:0051640 Not Cancer Driver No 42 0.099 170 15 0.088 0
STX10 STX10 O60499 Syntaxin-10 chr19 GO:0051640 Not Cancer Driver No 29 0.116 77 7 0.091 0
STX11 STX11 O75558 Syntaxin-11 chr6 GO:0051640 Not Cancer Driver No 71 0.247 48 7 0.146 0
STX12 STX12 Q86Y82 Syntaxin-12 chr1 GO:0051640 Not Cancer Driver No 21 0.076 156 9 0.058 0
STX16 STX16 O14662 Syntaxin-16 chr20 GO:0051640 Not Cancer Driver No 45 0.138 120 12 0.1 0
STX17_ENST00000534052 STX17 P56962 Syntaxin-17 chr9 GO:0051640 Not Cancer Driver No 27 0.089 81 4 0.049 0
STX19 STX19 Q8N4C7 Syntaxin-19 chr3 GO:0051640 Not Cancer Driver No 39 0.133 67 4 0.06 0
STX1A STX1A Q16623 Syntaxin-1A chr7 GO:0051640 Not Cancer Driver No 35 0.122 136 11 0.081 0
STX1B STX1B P61266 Syntaxin-1B chr16 GO:0051640 Not Cancer Driver No 38 0.132 155 20 0.129 2
STX2 STX2 P32856 Syntaxin-2 chr12 GO:0051640 Not Cancer Driver No 43 0.149 140 25 0.179 0
STX3 STX3 Q13277 Syntaxin-3 chr11 GO:0051640 Not Cancer Driver No 51 0.176 129 30 0.233 0
STX4 STX4 Q12846 Syntaxin-4 chr16 GO:0051640 Not Cancer Driver No 50 0.168 152 20 0.132 0
STX5 STX5 Q13190 Syntaxin-5 chr11 GO:0051640 Not Cancer Driver No 36 0.101 147 14 0.095 0
STX6 STX6 O43752 Syntaxin-6 chr1 GO:0051640 Not Cancer Driver No 33 0.129 78 11 0.141 0
STX7 STX7 O15400 Syntaxin-7 chr6 GO:0051640 Not Cancer Driver No 29 0.111 164 14 0.085 0
STX8 STX8 Q9UNK0 Syntaxin-8 chr17 GO:0051640 Not Cancer Driver No 32 0.136 98 10 0.102 0
STXBP1_ENST00000373299 STXBP1 P61764 Syntaxin-binding protein 1 chr9 GO:0051640 Not Cancer Driver No 97 0.163 111 23 0.207 18
STXBP2_ENST00000221283 STXBP2 Q15833 Syntaxin-binding protein 2 chr19 GO:0051640 Not Cancer Driver No 77 0.13 80 13 0.163 5
STXBP3 STXBP3 O00186 Syntaxin-binding protein 3 chr1 GO:0051640 Not Cancer Driver No 59 0.1 64 9 0.141 0
SUN1 SUN1 O94901 SUN domain-containing protein 1 chr7 GO:0051640 Not Cancer Driver No 109 0.139 246 26 0.106 0
SUN2_ENST00000405510 SUN2 Q9UH99 SUN domain-containing protein 2 chr22 GO:0051640 Not Cancer Driver No 74 0.103 214 18 0.084 0
SYBU_ENST00000276646 SYBU Q9NX95 Syntabulin chr8 GO:0051640 Not Cancer Driver No 134 0.202 437 91 0.208 0
SYN1 SYN1 P17600 Synapsin-1 chrX GO:0051640 Not Cancer Driver No 75 0.106 445 27 0.061 0
SYN2 SYN2 Q92777 Synapsin-2 chr3 GO:0051640 Not Cancer Driver No 56 0.096 295 21 0.071 0
SYN3 SYN3 O14994 Synapsin-3 chr22 GO:0051640 Not Cancer Driver No 94 0.162 292 47 0.161 0
SYNDIG1 SYNDIG1 Q9H7V2 Synapse differentiation-inducing gene protein 1 chr20 GO:0051640 Not Cancer Driver No 90 0.349 110 40 0.364 0
SYNE2_ENST00000344113 SYNE2 Q8WXH0 Nesprin-2 chr14 GO:0051640 Not Cancer Driver No 779 0.113 1888 220 0.117 1
SYT1_ENST00000393240 SYT1 P21579 Synaptotagmin-1 chr12 GO:0051640 Not Cancer Driver No 104 0.246 103 36 0.35 5
SYT4 SYT4 Q9H2B2 Synaptotagmin-4 chr18 GO:0051640 Not Cancer Driver No 111 0.261 107 41 0.383 0
SYTL2_ENST00000528231 SYTL2 Q9HCH5 Synaptotagmin-like protein 2 chr11 GO:0051640 Not Cancer Driver No 137 0.147 635 104 0.164 0
TANC2 TANC2 Q9HCD6 Protein TANC2 chr17 GO:0051640 Not Cancer Driver No 278 0.14 999 127 0.127 1
TBCCD1 TBCCD1 Q9NVR7 TBCC domain-containing protein 1 chr3 GO:0051640 Not Cancer Driver No 68 0.122 42 8 0.19 0
TERB1_ENST00000558713 TERB1 Q8NA31 Telomere repeats-binding bouquet formation protein 1 chr16 GO:0051640 Not Cancer Driver No 33 0.045 201 14 0.07 0
TERB2 TERB2 Q8NHR7 Telomere repeats-binding bouquet formation protein 2 chr15 GO:0051640 Not Cancer Driver No 38 0.173 35 5 0.143 0
TERF1 TERF1 P54274 Telomeric repeat-binding factor 1 chr8 GO:0051640 Not Cancer Driver No 63 0.144 220 34 0.155 0
TLE6 TLE6 Q9H808 Transducin-like enhancer protein 6 chr19 GO:0051640 Not Cancer Driver No 89 0.156 227 31 0.137 1
TMEM201 TMEM201 Q5SNT2 Transmembrane protein 201 chr1 GO:0051640 Not Cancer Driver No 50 0.075 241 18 0.075 0
TRAK1 TRAK1 Q9UPV9 Trafficking kinesin-binding protein 1 chr3 GO:0051640 Not Cancer Driver No 118 0.124 619 74 0.12 0
TRAK2 TRAK2 O60296 Trafficking kinesin-binding protein 2 chr2 GO:0051640 Not Cancer Driver No 112 0.123 576 70 0.122 0
TRIM46 TRIM46 Q7Z4K8 Tripartite motif-containing protein 46 chr1 GO:0051640 Not Cancer Driver No 115 0.152 173 30 0.173 0
TSG101 TSG101 Q99816 Tumor susceptibility gene 101 protein chr11 GO:0051640 Not Cancer Driver No 46 0.118 159 23 0.145 0
TSNARE1 TSNARE1 Q96NA8 t-SNARE domain-containing protein 1 chr8 GO:0051640 Not Cancer Driver No 99 0.193 292 58 0.199 0
UBB_ENST00000614404 UBB P0CG47 Polyubiquitin-B chr17 GO:0051640 Not Cancer Driver No 20 0.087 102 8 0.078 0
UBE2B UBE2B P63146 Ubiquitin-conjugating enzyme E2 B chr5 GO:0051640 Not Cancer Driver No 13 0.086 68 6 0.088 0
UCHL1 UCHL1 P09936 Ubiquitin carboxyl-terminal hydrolase isozyme L1 chr4 GO:0051640 Not Cancer Driver No 33 0.148 34 7 0.206 4
UNC13A UNC13A Q9UPW8 Protein unc-13 homolog A chr19 GO:0051640 Not Cancer Driver No 300 0.176 454 78 0.172 0
UNC13B_ENST00000378495 UNC13B O14795 Protein unc-13 homolog B chr9 GO:0051640 Not Cancer Driver No 214 0.135 448 77 0.172 0
UNC13C UNC13C Q8NB66 Protein unc-13 homolog C chr15 GO:0051640 Not Cancer Driver No 681 0.308 886 268 0.302 0
USO1_ENST00000514213 USO1 O60763 General vesicular transport factor p115 chr4 GO:0051640 Not Cancer Driver No 78 0.081 368 28 0.076 0
UVRAG UVRAG Q9P2Y5 UV radiation resistance-associated gene protein chr11 GO:0051640 Not Cancer Driver No 89 0.127 243 28 0.115 0
UXT_ENST00000333119 UXT Q9UBK9 Protein UXT chrX GO:0051640 Not Cancer Driver No 21 0.134 17 1 0.059 0
VAMP3 VAMP3 Q15836 Vesicle-associated membrane protein 3 chr1 GO:0051640 Not Cancer Driver No 11 0.11 17 1 0.059 0
VAMP8 VAMP8 Q9BV40 Vesicle-associated membrane protein 8 chr2 GO:0051640 Not Cancer Driver No 9 0.09 27 0 0.0 0
VAPB VAPB O95292 Vesicle-associated membrane protein-associated protein B/C chr20 GO:0051640 Not Cancer Driver No 16 0.066 138 8 0.058 3
VMP1 VMP1 Q96GC9 Vacuole membrane protein 1 chr17 GO:0051640 Not Cancer Driver No 57 0.14 68 11 0.162 0
VPS11 VPS11 Q9H270 Vacuolar protein sorting-associated protein 11 homolog chr11 GO:0051640 Not Cancer Driver No 96 0.102 118 6 0.051 1
VPS18 VPS18 Q9P253 Vacuolar protein sorting-associated protein 18 homolog chr15 GO:0051640 Not Cancer Driver No 96 0.099 86 7 0.081 0
VPS33A VPS33A Q96AX1 Vacuolar protein sorting-associated protein 33A chr12 GO:0051640 Not Cancer Driver No 73 0.122 46 8 0.174 1
VPS33B VPS33B Q9H267 Vacuolar protein sorting-associated protein 33B chr15 GO:0051640 Not Cancer Driver No 54 0.088 17 0 0.0 2
VTI1B VTI1B Q9UEU0 Vesicle transport through interaction with t-SNAREs homolog 1B chr14 GO:0051640 Not Cancer Driver No 25 0.108 192 20 0.104 0
WASF1_ENST00000392586 WASF1 Q92558 Wiskott-Aldrich syndrome protein family member 1 chr6 GO:0051640 Not Cancer Driver No 63 0.113 445 49 0.11 0
WASL WASL O00401 Neural Wiskott-Aldrich syndrome protein chr7 GO:0051640 Not Cancer Driver No 72 0.143 394 57 0.145 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 GO:0051640 Census, Compendium Yes 140 0.131 33 9 0.273 0
YKT6 YKT6 O15498 Synaptobrevin homolog YKT6 chr7 GO:0051640 Not Cancer Driver No 19 0.096 21 2 0.095 0
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 GO:0051640 Not Cancer Driver No 30 0.122 81 10 0.123 0
ZBED3 ZBED3 Q96IU2 Zinc finger BED domain-containing protein 3 chr5 GO:0051640 Not Cancer Driver No 2 0.009 229 2 0.009 0