Total number of protein in "GO:0051603" GO term: 102
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADAMTS12 | ADAMTS12 | P58397 | A disintegrin and metalloproteinase with thrombospondin motifs 12 | chr5 | GO:0051603 | Not Cancer Driver | No | 504 | 0.316 | 374 | 128 | 0.342 | 0 |
| ADAMTS7 | ADAMTS7 | Q9UKP4 | A disintegrin and metalloproteinase with thrombospondin motifs 7 | chr15 | GO:0051603 | Not Cancer Driver | No | 244 | 0.145 | 640 | 100 | 0.156 | 0 |
| ANAPC1 | ANAPC1 | Q9H1A4 | Anaphase-promoting complex subunit 1 | chr2 | GO:0051603 | Not Cancer Driver | No | 206 | 0.106 | 263 | 33 | 0.125 | 0 |
| ANAPC4_ENST00000315368 | ANAPC4 | Q9UJX5 | Anaphase-promoting complex subunit 4 | chr4 | GO:0051603 | Not Cancer Driver | No | 70 | 0.087 | 54 | 1 | 0.019 | 0 |
| ANAPC5 | ANAPC5 | Q9UJX4 | Anaphase-promoting complex subunit 5 | chr12 | GO:0051603 | Not Cancer Driver | No | 94 | 0.125 | 41 | 4 | 0.098 | 0 |
| ASCC2 | ASCC2 | Q9H1I8 | Activating signal cointegrator 1 complex subunit 2 | chr22 | GO:0051603 | Not Cancer Driver | No | 87 | 0.115 | 326 | 34 | 0.104 | 0 |
| ASCC3 | ASCC3 | Q8N3C0 | Activating signal cointegrator 1 complex subunit 3 | chr6 | GO:0051603 | Not Cancer Driver | No | 279 | 0.127 | 87 | 8 | 0.092 | 0 |
| AUP1 | AUP1 | Q9Y679 | Lipid droplet-regulating VLDL assembly factor AUP1 | chr2 | GO:0051603 | Not Cancer Driver | No | 41 | 0.1 | 122 | 13 | 0.107 | 0 |
| BAG6 | BAG6 | P46379 | Large proline-rich protein BAG6 | chr6 | GO:0051603 | Not Cancer Driver | No | 98 | 0.087 | 861 | 79 | 0.092 | 0 |
| C2orf40 | ECRG4 | Q9H1Z8 | Augurin | chr2 | GO:0051603 | Not Cancer Driver | No | 37 | 0.25 | 23 | 11 | 0.478 | 0 |
| CAPN2 | CAPN2 | P17655 | Calpain-2 catalytic subunit | chr1 | GO:0051603 | Not Cancer Driver | No | 81 | 0.116 | 46 | 11 | 0.239 | 0 |
| CASP8_ENST00000432109 | CASP8 | Q14790 | Caspase-8 | chr2 | GO:0051603 | Census, Compendium | Yes | 142 | 0.296 | 106 | 12 | 0.113 | 1 |
| CDC16_ENST00000356221 | CDC16 | Q13042 | Cell division cycle protein 16 homolog | chr13 | GO:0051603 | Not Cancer Driver | No | 68 | 0.11 | 54 | 7 | 0.13 | 0 |
| CDC20 | CDC20 | Q12834 | Cell division cycle protein 20 homolog | chr1 | GO:0051603 | Not Cancer Driver | No | 44 | 0.088 | 198 | 15 | 0.076 | 0 |
| CDC20B | CDC20B | Q86Y33 | Cell division cycle protein 20 homolog B | chr5 | GO:0051603 | Not Cancer Driver | No | 99 | 0.191 | 152 | 24 | 0.158 | 0 |
| CDC23 | CDC23 | Q9UJX2 | Cell division cycle protein 23 homolog | chr5 | GO:0051603 | Not Cancer Driver | No | 57 | 0.095 | 45 | 6 | 0.133 | 0 |
| CDC27_ENST00000066544 | CDC27 | P30260 | Cell division cycle protein 27 homolog | chr17 | GO:0051603 | Not Cancer Driver | No | 179 | 0.217 | 289 | 75 | 0.26 | 0 |
| CHMP4B | CHMP4B | Q9H444 | Charged multivesicular body protein 4b | chr20 | GO:0051603 | Not Cancer Driver | No | 25 | 0.112 | 201 | 22 | 0.109 | 2 |
| CHMP4C | CHMP4C | Q96CF2 | Charged multivesicular body protein 4c | chr8 | GO:0051603 | Not Cancer Driver | No | 33 | 0.142 | 224 | 31 | 0.138 | 0 |
| CLPP | CLPP | Q16740 | ATP-dependent Clp protease proteolytic subunit, mitochondrial | chr19 | GO:0051603 | Not Cancer Driver | No | 22 | 0.079 | 83 | 9 | 0.108 | 3 |
| CLPX | CLPX | O76031 | ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial | chr15 | GO:0051603 | Not Cancer Driver | No | 66 | 0.104 | 195 | 22 | 0.113 | 1 |
| CTSB | CTSB | P07858 | Cathepsin B | chr8 | GO:0051603 | Not Cancer Driver | No | 41 | 0.121 | 7 | 2 | 0.286 | 0 |
| CTSC | CTSC | P53634 | Dipeptidyl peptidase 1 | chr11 | GO:0051603 | Not Cancer Driver | No | 64 | 0.138 | 19 | 5 | 0.263 | 29 |
| CTSF | CTSF | Q9UBX1 | Cathepsin F | chr11 | GO:0051603 | Not Cancer Driver | No | 63 | 0.13 | 78 | 7 | 0.09 | 4 |
| CTSH | CTSH | P09668 | Pro-cathepsin H | chr15 | GO:0051603 | Not Cancer Driver | No | 45 | 0.134 | 4 | 0 | 0.0 | 0 |
| CTSK | CTSK | P43235 | Cathepsin K | chr1 | GO:0051603 | Not Cancer Driver | No | 36 | 0.109 | 24 | 4 | 0.167 | 6 |
| CTSL | CTSL | P07711 | Procathepsin L | chr9 | GO:0051603 | Not Cancer Driver | No | 47 | 0.141 | 34 | 4 | 0.118 | 0 |
| CTSO | CTSO | P43234 | Cathepsin O | chr4 | GO:0051603 | Not Cancer Driver | No | 39 | 0.121 | 8 | 0 | 0.0 | 0 |
| CTSS | CTSS | P25774 | Cathepsin S | chr1 | GO:0051603 | Not Cancer Driver | No | 54 | 0.163 | 0 | 0 | 0.0 | 0 |
| CTSV | CTSV | O60911 | Cathepsin L2 | chr9 | GO:0051603 | Not Cancer Driver | No | 55 | 0.165 | 7 | 1 | 0.143 | 0 |
| CTSW | CTSW | P56202 | Cathepsin W | chr11 | GO:0051603 | Not Cancer Driver | No | 58 | 0.154 | 59 | 10 | 0.169 | 0 |
| CTSZ | CTSZ | Q9UBR2 | Cathepsin Z | chr20 | GO:0051603 | Not Cancer Driver | No | 30 | 0.099 | 10 | 0 | 0.0 | 0 |
| CUL3 | CUL3 | Q13618 | Cullin-3 | chr2 | GO:0051603 | Census, Compendium | Yes | 123 | 0.16 | 167 | 23 | 0.138 | 3 |
| DCAF12 | DCAF12 | Q5T6F0 | DDB1- and CUL4-associated factor 12 | chr9 | GO:0051603 | Not Cancer Driver | No | 59 | 0.13 | 70 | 7 | 0.1 | 0 |
| DERL1 | DERL1 | Q9BUN8 | Derlin-1 | chr8 | GO:0051603 | Not Cancer Driver | No | 28 | 0.112 | 11 | 1 | 0.091 | 0 |
| DNAJC3 | DNAJC3 | Q13217 | DnaJ homolog subfamily C member 3 | chr13 | GO:0051603 | Not Cancer Driver | No | 60 | 0.119 | 131 | 17 | 0.13 | 0 |
| EDEM1 | EDEM1 | Q92611 | ER degradation-enhancing alpha-mannosidase-like protein 1 | chr3 | GO:0051603 | Not Cancer Driver | No | 54 | 0.082 | 141 | 5 | 0.035 | 0 |
| EDEM2 | EDEM2 | Q9BV94 | ER degradation-enhancing alpha-mannosidase-like protein 2 | chr20 | GO:0051603 | Not Cancer Driver | No | 69 | 0.119 | 54 | 3 | 0.056 | 0 |
| ENC1_ENST00000302351 | ENC1 | O14682 | Ectoderm-neural cortex protein 1 | chr5 | GO:0051603 | Not Cancer Driver | No | 85 | 0.144 | 8 | 0 | 0.0 | 0 |
| FAP | FAP | Q12884 | Prolyl endopeptidase FAP | chr2 | GO:0051603 | Not Cancer Driver | No | 158 | 0.208 | 6 | 2 | 0.333 | 0 |
| FBXO31 | FBXO31 | Q5XUX0 | F-box only protein 31 | chr16 | GO:0051603 | Not Cancer Driver | No | 72 | 0.134 | 231 | 30 | 0.13 | 0 |
| FEM1A | FEM1A | Q9BSK4 | Protein fem-1 homolog A | chr19 | GO:0051603 | Not Cancer Driver | No | 68 | 0.102 | 162 | 22 | 0.136 | 0 |
| FEM1B | FEM1B | Q9UK73 | Protein fem-1 homolog B | chr15 | GO:0051603 | Not Cancer Driver | No | 69 | 0.11 | 33 | 3 | 0.091 | 0 |
| FEM1C | FEM1C | Q96JP0 | Protein fem-1 homolog C | chr5 | GO:0051603 | Not Cancer Driver | No | 55 | 0.089 | 27 | 1 | 0.037 | 0 |
| FZR1 | FZR1 | Q9UM11 | Fizzy-related protein homolog | chr19 | GO:0051603 | Not Cancer Driver | No | 74 | 0.149 | 184 | 30 | 0.163 | 0 |
| GZMA | GZMA | P12544 | Granzyme A | chr5 | GO:0051603 | Not Cancer Driver | No | 70 | 0.267 | 5 | 1 | 0.2 | 0 |
| GZMB | GZMB | P10144 | Granzyme B | chr14 | GO:0051603 | Not Cancer Driver | No | 49 | 0.198 | 103 | 23 | 0.223 | 0 |
| HM13_ENST00000340852 | HM13 | Q8TCT9 | Minor histocompatibility antigen H13 | chr20 | GO:0051603 | Not Cancer Driver | No | 42 | 0.111 | 61 | 6 | 0.098 | 0 |
| IDE | IDE | P14735 | Insulin-degrading enzyme | chr10 | GO:0051603 | Not Cancer Driver | No | 90 | 0.088 | 96 | 8 | 0.083 | 0 |
| KLHDC1 | KLHDC1 | Q8N7A1 | Kelch domain-containing protein 1 | chr14 | GO:0051603 | Not Cancer Driver | No | 36 | 0.089 | 37 | 7 | 0.189 | 0 |
| KLHDC10 | KLHDC10 | Q6PID8 | Kelch domain-containing protein 10 | chr7 | GO:0051603 | Not Cancer Driver | No | 40 | 0.09 | 93 | 3 | 0.032 | 0 |
| KLHDC2 | KLHDC2 | Q9Y2U9 | Kelch domain-containing protein 2 | chr14 | GO:0051603 | Not Cancer Driver | No | 39 | 0.096 | 42 | 2 | 0.048 | 0 |
| KLHDC3 | KLHDC3 | Q9BQ90 | Kelch domain-containing protein 3 | chr6 | GO:0051603 | Not Cancer Driver | No | 43 | 0.113 | 12 | 1 | 0.083 | 0 |
| KLHL15 | KLHL15 | Q96M94 | Kelch-like protein 15 | chrX | GO:0051603 | Not Cancer Driver | No | 74 | 0.123 | 25 | 4 | 0.16 | 0 |
| LGMN_ENST00000334869 | LGMN | Q99538 | Legumain | chr14 | GO:0051603 | Not Cancer Driver | No | 57 | 0.132 | 112 | 19 | 0.17 | 0 |
| LONP1 | LONP1 | P36776 | Lon protease homolog, mitochondrial | chr19 | GO:0051603 | Not Cancer Driver | No | 99 | 0.103 | 175 | 15 | 0.086 | 10 |
| LTN1_ENST00000361371 | LTN1 | O94822 | E3 ubiquitin-protein ligase listerin | chr21 | GO:0051603 | Not Cancer Driver | No | 192 | 0.109 | 124 | 23 | 0.185 | 0 |
| MALT1 | MALT1 | Q9UDY8 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | chr18 | GO:0051603 | Census, Compendium | Yes | 75 | 0.091 | 139 | 12 | 0.086 | 1 |
| MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | GO:0051603 | Census, Compendium | Yes | 56 | 0.114 | 297 | 37 | 0.125 | 0 |
| NEMF | NEMF | O60524 | Ribosome quality control complex subunit NEMF | chr14 | GO:0051603 | Not Cancer Driver | No | 109 | 0.101 | 517 | 61 | 0.118 | 0 |
| NFE2L2 | NFE2L2 | Q16236 | Nuclear factor erythroid 2-related factor 2 | chr2 | GO:0051603 | Census, Compendium | Yes | 228 | 0.377 | 402 | 62 | 0.154 | 4 |
| NGLY1 | NGLY1 | Q96IV0 | Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase | chr3 | GO:0051603 | Not Cancer Driver | No | 79 | 0.121 | 98 | 13 | 0.133 | 0 |
| OMA1 | OMA1 | Q96E52 | Metalloendopeptidase OMA1, mitochondrial | chr1 | GO:0051603 | Not Cancer Driver | No | 52 | 0.099 | 34 | 4 | 0.118 | 0 |
| OTUD7A | OTUD7A | Q8TE49 | OTU domain-containing protein 7A | chr15 | GO:0051603 | Not Cancer Driver | No | 121 | 0.131 | 591 | 65 | 0.11 | 0 |
| OTUD7B | OTUD7B | Q6GQQ9 | OTU domain-containing protein 7B | chr1 | GO:0051603 | Not Cancer Driver | No | 124 | 0.147 | 537 | 87 | 0.162 | 0 |
| PCYOX1 | PCYOX1 | Q9UHG3 | Prenylcysteine oxidase 1 | chr2 | GO:0051603 | Not Cancer Driver | No | 60 | 0.119 | 9 | 1 | 0.111 | 0 |
| PCYOX1L | PCYOX1L | Q8NBM8 | Prenylcysteine oxidase-like | chr5 | GO:0051603 | Not Cancer Driver | No | 61 | 0.123 | 0 | 0 | 0.0 | 0 |
| PDCD6IP_ENST00000307296 | PDCD6IP | Q8WUM4 | Programmed cell death 6-interacting protein | chr3 | GO:0051603 | Not Cancer Driver | No | 85 | 0.098 | 272 | 22 | 0.081 | 0 |
| PSMA6 | PSMA6 | P60900 | Proteasome subunit alpha type-6 | chr14 | GO:0051603 | Not Cancer Driver | No | 37 | 0.15 | 2 | 1 | 0.5 | 0 |
| PSME4 | PSME4 | Q14997 | Proteasome activator complex subunit 4 | chr2 | GO:0051603 | Not Cancer Driver | No | 214 | 0.116 | 134 | 12 | 0.09 | 0 |
| RHBDD1 | RHBDD1 | Q8TEB9 | Rhomboid-related protein 4 | chr2 | GO:0051603 | Not Cancer Driver | No | 38 | 0.121 | 69 | 9 | 0.13 | 0 |
| RNF111_ENST00000557998 | RNF111 | Q6ZNA4 | E3 ubiquitin-protein ligase Arkadia | chr15 | GO:0051603 | Not Cancer Driver | No | 111 | 0.112 | 855 | 96 | 0.112 | 0 |
| RNF123 | RNF123 | Q5XPI4 | E3 ubiquitin-protein ligase RNF123 | chr3 | GO:0051603 | Not Cancer Driver | No | 167 | 0.127 | 220 | 28 | 0.127 | 0 |
| RNF126 | RNF126 | Q9BV68 | E3 ubiquitin-protein ligase RNF126 | chr19 | GO:0051603 | Not Cancer Driver | No | 33 | 0.106 | 182 | 22 | 0.121 | 0 |
| RNF185 | RNF185 | Q96GF1 | E3 ubiquitin-protein ligase RNF185 | chr22 | GO:0051603 | Not Cancer Driver | No | 25 | 0.13 | 82 | 15 | 0.183 | 0 |
| RNF5 | RNF5 | Q99942 | E3 ubiquitin-protein ligase RNF5 | chr6 | GO:0051603 | Not Cancer Driver | No | 17 | 0.094 | 69 | 3 | 0.043 | 0 |
| RSPRY1_ENST00000394420 | RSPRY1 | Q96DX4 | RING finger and SPRY domain-containing protein 1 | chr16 | GO:0051603 | Not Cancer Driver | No | 64 | 0.111 | 98 | 18 | 0.184 | 1 |
| SDF2L1 | SDF2L1 | Q9HCN8 | Stromal cell-derived factor 2-like protein 1 | chr22 | GO:0051603 | Not Cancer Driver | No | 16 | 0.072 | 130 | 9 | 0.069 | 0 |
| SMURF1 | SMURF1 | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 | chr7 | GO:0051603 | Not Cancer Driver | No | 89 | 0.118 | 256 | 31 | 0.121 | 0 |
| SMURF2 | SMURF2 | Q9HAU4 | E3 ubiquitin-protein ligase SMURF2 | chr17 | GO:0051603 | Not Cancer Driver | No | 87 | 0.116 | 242 | 28 | 0.116 | 0 |
| STUB1 | STUB1 | Q9UNE7 | E3 ubiquitin-protein ligase CHIP | chr16 | GO:0051603 | Not Cancer Driver | No | 35 | 0.116 | 112 | 14 | 0.125 | 12 |
| TAF1_ENST00000373790 | TAF1 | P21675 | Transcription initiation factor TFIID subunit 1 | chrX | GO:0051603 | Not Cancer Driver | No | 379 | 0.202 | 1152 | 219 | 0.19 | 5 |
| TGFB1I1 | TGFB1I1 | O43294 | Transforming growth factor beta-1-induced transcript 1 protein | chr16 | GO:0051603 | Not Cancer Driver | No | 61 | 0.132 | 219 | 34 | 0.155 | 0 |
| TNFAIP3 | TNFAIP3 | P21580 | Tumor necrosis factor alpha-induced protein 3 | chr6 | GO:0051603 | Census, Compendium | Yes | 98 | 0.124 | 231 | 33 | 0.143 | 1 |
| TOR1A | TOR1A | O14656 | Torsin-1A | chr9 | GO:0051603 | Not Cancer Driver | No | 33 | 0.099 | 0 | 0 | 0.0 | 3 |
| TRIP4 | TRIP4 | Q15650 | Activating signal cointegrator 1 | chr15 | GO:0051603 | Not Cancer Driver | No | 71 | 0.122 | 176 | 27 | 0.153 | 0 |
| TRPC4AP | TRPC4AP | Q8TEL6 | Short transient receptor potential channel 4-associated protein | chr20 | GO:0051603 | Not Cancer Driver | No | 84 | 0.105 | 70 | 7 | 0.1 | 0 |
| UBE2C | UBE2C | O00762 | Ubiquitin-conjugating enzyme E2 C | chr20 | GO:0051603 | Not Cancer Driver | No | 13 | 0.073 | 40 | 0 | 0.0 | 0 |
| UBE2S | UBE2S | Q16763 | Ubiquitin-conjugating enzyme E2 S | chr19 | GO:0051603 | Not Cancer Driver | No | 25 | 0.113 | 102 | 12 | 0.118 | 0 |
| UBR1 | UBR1 | Q8IWV7 | E3 ubiquitin-protein ligase UBR1 | chr15 | GO:0051603 | Not Cancer Driver | No | 170 | 0.097 | 165 | 15 | 0.091 | 18 |
| UBR2 | UBR2 | Q8IWV8 | E3 ubiquitin-protein ligase UBR2 | chr6 | GO:0051603 | Not Cancer Driver | No | 172 | 0.098 | 228 | 30 | 0.132 | 0 |
| UBR3 | UBR3 | Q6ZT12 | E3 ubiquitin-protein ligase UBR3 | chr2 | GO:0051603 | Not Cancer Driver | No | 154 | 0.082 | 339 | 28 | 0.083 | 0 |
| UFD1 | UFD1 | Q92890 | Ubiquitin recognition factor in ER-associated degradation protein 1 | chr22 | GO:0051603 | Not Cancer Driver | No | 26 | 0.085 | 100 | 7 | 0.07 | 0 |
| UGGT1 | UGGT1 | Q9NYU2 | UDP-glucose:glycoprotein glucosyltransferase 1 | chr2 | GO:0051603 | Not Cancer Driver | No | 169 | 0.109 | 161 | 20 | 0.124 | 0 |
| UGGT2 | UGGT2 | Q9NYU1 | UDP-glucose:glycoprotein glucosyltransferase 2 | chr13 | GO:0051603 | Not Cancer Driver | No | 190 | 0.125 | 64 | 6 | 0.094 | 0 |
| USP9X_ENST00000378308 | USP9X | Q93008 | Probable ubiquitin carboxyl-terminal hydrolase FAF-X | chrX | GO:0051603 | Census, Compendium | Yes | 339 | 0.133 | 405 | 51 | 0.126 | 1 |
| VCP | VCP | P55072 | Transitional endoplasmic reticulum ATPase | chr9 | GO:0051603 | Not Cancer Driver | No | 88 | 0.109 | 186 | 16 | 0.086 | 16 |
| VPS4A | VPS4A | Q9UN37 | Vacuolar protein sorting-associated protein 4A | chr16 | GO:0051603 | Not Cancer Driver | No | 48 | 0.11 | 167 | 17 | 0.102 | 4 |
| VPS4B | VPS4B | O75351 | Vacuolar protein sorting-associated protein 4B | chr18 | GO:0051603 | Not Cancer Driver | No | 52 | 0.117 | 195 | 22 | 0.113 | 0 |
| WNT1 | WNT1 | P04628 | Proto-oncogene Wnt-1 | chr12 | GO:0051603 | Not Cancer Driver | No | 29 | 0.078 | 25 | 0 | 0.0 | 8 |
| ZMPSTE24 | ZMPSTE24 | O75844 | CAAX prenyl protease 1 homolog | chr1 | GO:0051603 | Not Cancer Driver | No | 67 | 0.141 | 23 | 0 | 0.0 | 3 |
| ZRANB1 | ZRANB1 | Q9UGI0 | Ubiquitin thioesterase ZRANB1 | chr10 | GO:0051603 | Not Cancer Driver | No | 87 | 0.123 | 158 | 25 | 0.158 | 0 |