Total number of protein in "GO:0051402" GO term: 50
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADARB1 | ADARB1 | P78563 | Double-stranded RNA-specific editase 1 | chr21 | GO:0051402 | Not Cancer Driver | No | 102 | 0.138 | 348 | 34 | 0.098 | 1 |
| AIFM1 | AIFM1 | O95831 | Apoptosis-inducing factor 1, mitochondrial | chrX | GO:0051402 | Not Cancer Driver | No | 88 | 0.144 | 166 | 22 | 0.133 | 11 |
| AKT2 | AKT2 | P31751 | RAC-beta serine/threonine-protein kinase | chr19 | GO:0051402 | Census | Yes | 77 | 0.16 | 84 | 9 | 0.107 | 2 |
| APAF1 | APAF1 | O14727 | Apoptotic protease-activating factor 1 | chr12 | GO:0051402 | Not Cancer Driver | No | 127 | 0.102 | 17 | 1 | 0.059 | 0 |
| APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | GO:0051402 | Not Cancer Driver | No | 128 | 0.166 | 418 | 71 | 0.17 | 17 |
| ATF2 | ATF2 | P15336 | Cyclic AMP-dependent transcription factor ATF-2 | chr2 | GO:0051402 | Not Cancer Driver | No | 65 | 0.129 | 451 | 58 | 0.129 | 0 |
| ATM_ENST00000452508 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:0051402 | Census, Compendium | Yes | 469 | 0.153 | 225 | 39 | 0.173 | 41 |
| ATN1_ENST00000396684 | ATN1 | P54259 | Atrophin-1 | chr12 | GO:0051402 | Not Cancer Driver | No | 141 | 0.118 | 1176 | 139 | 0.118 | 6 |
| BAX_ENST00000345358 | BAX | Q07812 | Apoptosis regulator BAX | chr19 | GO:0051402 | Census | Yes | 30 | 0.156 | 39 | 2 | 0.051 | 0 |
| BCL2L1 | BCL2L1 | Q07817 | Bcl-2-like protein 1 | chr20 | GO:0051402 | Not Cancer Driver | No | 29 | 0.124 | 55 | 3 | 0.055 | 0 |
| BCL2_ENST00000333681 | BCL2 | P10415 | Apoptosis regulator Bcl-2 | chr18 | GO:0051402 | Census, Compendium | Yes | 24 | 0.1 | 72 | 5 | 0.069 | 0 |
| BID_ENST00000551952 | BID | P55957 | BH3-interacting domain death agonist | chr22 | GO:0051402 | Not Cancer Driver | No | 23 | 0.118 | 74 | 9 | 0.122 | 0 |
| BOK | BOK | Q9UMX3 | Bcl-2-related ovarian killer protein | chr2 | GO:0051402 | Not Cancer Driver | No | 7 | 0.033 | 0 | 0 | 0.0 | 0 |
| CASP3 | CASP3 | P42574 | Caspase-3 | chr4 | GO:0051402 | Census | Yes | 32 | 0.116 | 62 | 5 | 0.081 | 0 |
| CASP7_ENST00000345633 | CASP7 | P55210 | Caspase-7 | chr10 | GO:0051402 | Not Cancer Driver | No | 38 | 0.125 | 73 | 10 | 0.137 | 0 |
| CDK5 | CDK5 | Q00535 | Cyclin-dependent kinase 5 | chr7 | GO:0051402 | Not Cancer Driver | No | 48 | 0.164 | 5 | 1 | 0.2 | 0 |
| CIT_ENST00000261833 | CIT | O14578 | Citron Rho-interacting kinase | chr12 | GO:0051402 | Not Cancer Driver | No | 284 | 0.14 | 1017 | 160 | 0.157 | 3 |
| DIABLO | DIABLO | Q9NR28 | Diablo IAP-binding mitochondrial protein | chr12 | GO:0051402 | Not Cancer Driver | No | 62 | 0.259 | 54 | 8 | 0.148 | 1 |
| DIO3 | DIO3 | P55073 | Thyroxine 5-deiodinase | chr14 | GO:0051402 | Not Cancer Driver | No | 88 | 0.289 | 71 | 18 | 0.254 | 0 |
| ERBB3 | ERBB3 | P21860 | Receptor tyrosine-protein kinase erbB-3 | chr12 | GO:0051402 | Census, Compendium | Yes | 298 | 0.222 | 396 | 70 | 0.177 | 3 |
| FADD | FADD | Q13158 | FAS-associated death domain protein | chr11 | GO:0051402 | Not Cancer Driver | No | 26 | 0.125 | 45 | 10 | 0.222 | 1 |
| FAM162A | FAM162A | Q96A26 | Protein FAM162A | chr3 | GO:0051402 | Not Cancer Driver | No | 18 | 0.117 | 53 | 8 | 0.151 | 0 |
| FAS | FAS | P25445 | Tumor necrosis factor receptor superfamily member 6 | chr10 | GO:0051402 | Census, Compendium | Yes | 55 | 0.164 | 62 | 18 | 0.29 | 22 |
| GAPDH | GAPDH | P04406 | Glyceraldehyde-3-phosphate dehydrogenase | chr12 | GO:0051402 | Not Cancer Driver | No | 39 | 0.116 | 24 | 3 | 0.125 | 0 |
| GBA_ENST00000368373 | GBA | P04062 | Lysosomal acid glucosylceramidase | chr1 | GO:0051402 | Not Cancer Driver | No | 74 | 0.138 | 38 | 5 | 0.132 | 171 |
| GPX1_ENST00000620890 | GPX1 | P07203 | Glutathione peroxidase 1 | chr3 | GO:0051402 | Not Cancer Driver | No | 38 | 0.187 | 12 | 1 | 0.083 | 0 |
| GRIK2 | GRIK2 | Q13002 | Glutamate receptor ionotropic, kainate 2 | chr6 | GO:0051402 | Not Cancer Driver | No | 284 | 0.313 | 57 | 19 | 0.333 | 0 |
| HSPA5 | HSPA5 | P11021 | Endoplasmic reticulum chaperone BiP | chr9 | GO:0051402 | Not Cancer Driver | No | 73 | 0.112 | 282 | 35 | 0.124 | 0 |
| LIG4 | LIG4 | P49917 | DNA ligase 4 | chr13 | GO:0051402 | Not Cancer Driver | No | 134 | 0.147 | 63 | 10 | 0.159 | 2 |
| MAX | MAX | P61244 | Protein max | chr14 | GO:0051402 | Census, Compendium | Yes | 45 | 0.281 | 160 | 45 | 0.281 | 9 |
| NAE1_ENST00000290810 | NAE1 | Q13564 | NEDD8-activating enzyme E1 regulatory subunit | chr16 | GO:0051402 | Not Cancer Driver | No | 39 | 0.073 | 69 | 3 | 0.043 | 0 |
| NCSTN | NCSTN | Q92542 | Nicastrin | chr1 | GO:0051402 | Not Cancer Driver | No | 94 | 0.133 | 72 | 11 | 0.153 | 1 |
| NGFR | NGFR | P08138 | Tumor necrosis factor receptor superfamily member 16 | chr17 | GO:0051402 | Not Cancer Driver | No | 57 | 0.133 | 172 | 25 | 0.145 | 0 |
| NLRP1_ENST00000572272 | NLRP1 | Q9C000 | NACHT, LRR and PYD domains-containing protein 1 | chr17 | GO:0051402 | Not Cancer Driver | No | 222 | 0.151 | 340 | 65 | 0.191 | 6 |
| OXR1 | OXR1 | Q8N573 | Oxidation resistance protein 1 | chr8 | GO:0051402 | Not Cancer Driver | No | 126 | 0.144 | 544 | 76 | 0.14 | 0 |
| PIGT | PIGT | Q969N2 | GPI transamidase component PIG-T | chr20 | GO:0051402 | Not Cancer Driver | No | 51 | 0.088 | 36 | 6 | 0.167 | 1 |
| POLB | POLB | P06746 | DNA polymerase beta | chr8 | GO:0051402 | Not Cancer Driver | No | 43 | 0.128 | 87 | 11 | 0.126 | 0 |
| POU4F3 | POU4F3 | Q15319 | POU domain, class 4, transcription factor 3 | chr5 | GO:0051402 | Not Cancer Driver | No | 62 | 0.183 | 198 | 39 | 0.197 | 10 |
| PSEN1 | PSEN1 | P49768 | Presenilin-1 | chr14 | GO:0051402 | Not Cancer Driver | No | 61 | 0.131 | 134 | 21 | 0.157 | 96 |
| RB1 | RB1 | P06400 | Retinoblastoma-associated protein | chr13 | GO:0051402 | Census, Compendium | Yes | 140 | 0.151 | 282 | 32 | 0.113 | 22 |
| SCN2A_ENST00000637266 | SCN2A | Q99250 | Sodium channel protein type 2 subunit alpha | chr2 | GO:0051402 | Not Cancer Driver | No | 502 | 0.25 | 435 | 133 | 0.306 | 65 |
| SIAH1_ENST00000394725 | SIAH1 | Q8IUQ4 | E3 ubiquitin-protein ligase SIAH1 | chr16 | GO:0051402 | Not Cancer Driver | No | 35 | 0.124 | 28 | 2 | 0.071 | 5 |
| SLC1A1 | SLC1A1 | P43005 | Excitatory amino acid transporter 3 | chr9 | GO:0051402 | Not Cancer Driver | No | 69 | 0.132 | 17 | 4 | 0.235 | 1 |
| THRB_ENST00000415021 | THRB | P10828 | Thyroid hormone receptor beta | chr3 | GO:0051402 | Not Cancer Driver | No | 87 | 0.189 | 113 | 28 | 0.248 | 33 |
| TMTC4_ENST00000376234 | TMTC4 | Q5T4D3 | Protein O-mannosyl-transferase TMTC4 | chr13 | GO:0051402 | Not Cancer Driver | No | 105 | 0.142 | 0 | 0 | 0.0 | 0 |
| TNFRSF21 | TNFRSF21 | O75509 | Tumor necrosis factor receptor superfamily member 21 | chr6 | GO:0051402 | Not Cancer Driver | No | 98 | 0.15 | 280 | 46 | 0.164 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0051402 | Census, Compendium | Yes | 2891 | 7.356 | 282 | 1466 | 5.199 | 83 |
| TP63 | TP63 | Q9H3D4 | Tumor protein 63 | chr3 | GO:0051402 | Census, Compendium | Yes | 229 | 0.337 | 398 | 143 | 0.359 | 28 |
| TRPC5 | TRPC5 | Q9UL62 | Short transient receptor potential channel 5 | chrX | GO:0051402 | Not Cancer Driver | No | 255 | 0.262 | 148 | 32 | 0.216 | 0 |
| XIAP_ENST00000434753 | XIAP | P98170 | E3 ubiquitin-protein ligase XIAP | chrX | GO:0051402 | Not Cancer Driver | No | 89 | 0.179 | 55 | 6 | 0.109 | 0 |