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Total number of protein in "GO:0051235" GO term:  119

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AKAP9 AKAP9 Q99996 A-kinase anchor protein 9 chr7 GO:0051235 Census Yes 474 0.121 2281 268 0.117 1
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0051235 Census, Compendium Yes 108 0.225 158 24 0.152 4
AL132671.2 AL132671.2 A0A0J9YVX5 Uncharacterized protein (Fragment) chr6 GO:0051235 Not Cancer Driver No 54 0.174 128 26 0.203 0
ALB ALB P02768 Albumin chr4 GO:0051235 Compendium Yes 162 0.266 6 0 0.0 3
ANK3 ANK3 Q12955 Ankyrin-3 chr10 GO:0051235 Not Cancer Driver No 860 0.196 3054 579 0.19 0
ANKRD13C ANKRD13C Q8N6S4 Ankyrin repeat domain-containing protein 13C chr1 GO:0051235 Not Cancer Driver No 71 0.131 193 24 0.124 0
ARHGAP21 ARHGAP21 Q5T5U3 Rho GTPase-activating protein 21 chr10 GO:0051235 Not Cancer Driver No 242 0.124 1612 204 0.127 0
ARL2 ARL2 P36404 ADP-ribosylation factor-like protein 2 chr11 GO:0051235 Not Cancer Driver No 19 0.103 0 0 0.0 1
ARL2BP ARL2BP Q9Y2Y0 ADP-ribosylation factor-like protein 2-binding protein chr16 GO:0051235 Not Cancer Driver No 16 0.098 5 0 0.0 1
ASPM ASPM Q8IZT6 Abnormal spindle-like microcephaly-associated protein chr1 GO:0051235 Not Cancer Driver No 554 0.159 424 67 0.158 0
ATP2A1 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 GO:0051235 Not Cancer Driver No 157 0.157 80 11 0.138 1
BARD1 BARD1 Q99728 BRCA1-associated RING domain protein 1 chr2 GO:0051235 Census Yes 96 0.124 384 49 0.128 0
BBS4 BBS4 Q96RK4 Bardet-Biedl syndrome 4 protein chr15 GO:0051235 Not Cancer Driver No 58 0.112 110 16 0.145 9
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0051235 Not Cancer Driver No 30 0.169 2 0 0.0 0
CCDC22 CCDC22 O60826 Coiled-coil domain-containing protein 22 chrX GO:0051235 Not Cancer Driver No 62 0.099 243 18 0.074 2
CCDC88A_ENST00000642200 CCDC88A Q3V6T2 Girdin chr2 GO:0051235 Not Cancer Driver No 226 0.121 1481 173 0.117 0
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 GO:0051235 Not Cancer Driver No 69 0.151 56 11 0.196 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0051235 Not Cancer Driver No 48 0.164 5 1 0.2 0
CER1 CER1 O95813 Cerberus chr9 GO:0051235 Not Cancer Driver No 70 0.262 119 27 0.227 0
CHCHD10_ENST00000484558 CHCHD10 Q8WYQ3 Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial chr22 GO:0051235 Not Cancer Driver No 8 0.056 97 4 0.041 4
CIZ1_ENST00000634901 CIZ1 Q9ULV3 Cip1-interacting zinc finger protein chr9 GO:0051235 Not Cancer Driver No 93 0.104 708 83 0.117 0
DAND5 DAND5 Q8N907 DAN domain family member 5 chr19 GO:0051235 Not Cancer Driver No 32 0.169 26 3 0.115 0
DBN1_ENST00000309007 DBN1 Q16643 Drebrin chr5 GO:0051235 Not Cancer Driver No 84 0.129 510 73 0.143 0
DZIP1_ENST00000376829 DZIP1 Q86YF9 Cilium assembly protein DZIP1 chr13 GO:0051235 Not Cancer Driver No 143 0.165 523 92 0.176 2
ENPP1 ENPP1 P22413 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 chr6 GO:0051235 Not Cancer Driver No 148 0.16 101 5 0.05 33
FAF1 FAF1 Q9UNN5 FAS-associated factor 1 chr1 GO:0051235 Not Cancer Driver No 83 0.128 241 34 0.141 0
FBN1 FBN1 P35555 Fibrillin-1 chr15 GO:0051235 Not Cancer Driver No 466 0.162 110 16 0.145 360
FBN2_ENST00000262464 FBN2 P35556 Fibrillin-2 chr5 GO:0051235 Compendium Yes 607 0.208 135 24 0.178 30
FITM2 FITM2 Q8N6M3 Acyl-coenzyme A diphosphatase FITM2 chr20 GO:0051235 Not Cancer Driver No 28 0.107 0 0 0.0 1
FLNA FLNA P21333 Filamin-A chrX GO:0051235 Census Yes 416 0.157 1456 214 0.147 28
FTH1_ENST00000620041 FTH1 P02794 Ferritin heavy chain chr11 GO:0051235 Not Cancer Driver No 20 0.109 57 7 0.123 0
FTHL17 FTHL17 Q9BXU8 Ferritin heavy polypeptide-like 17 chrX GO:0051235 Not Cancer Driver No 63 0.344 9 1 0.111 0
FTL FTL P02792 Ferritin light chain chr19 GO:0051235 Not Cancer Driver No 19 0.109 36 7 0.194 2
FTMT FTMT Q8N4E7 Ferritin, mitochondrial chr5 GO:0051235 Not Cancer Driver No 96 0.397 93 33 0.355 0
G3BP2_ENST00000395719 G3BP2 Q9UN86 Ras GTPase-activating protein-binding protein 2 chr4 GO:0051235 Not Cancer Driver No 64 0.133 384 53 0.138 0
GAA_ENST00000390015 GAA P10253 Lysosomal alpha-glucosidase chr17 GO:0051235 Not Cancer Driver No 101 0.106 147 18 0.122 131
GET4 GET4 Q7L5D6 Golgi to ER traffic protein 4 homolog chr7 GO:0051235 Not Cancer Driver No 34 0.104 51 3 0.059 0
GOLPH3 GOLPH3 Q9H4A6 Golgi phosphoprotein 3 chr5 GO:0051235 Not Cancer Driver No 41 0.138 72 1 0.014 0
GOPC GOPC Q9HD26 Golgi-associated PDZ and coiled-coil motif-containing protein chr6 GO:0051235 Census Yes 56 0.121 263 34 0.129 0
GPAA1 GPAA1 O43292 Glycosylphosphatidylinositol anchor attachment 1 protein chr8 GO:0051235 Not Cancer Driver No 55 0.089 20 3 0.15 5
GPSM2_ENST00000642355 GPSM2 P81274 G-protein-signaling modulator 2 chr1 GO:0051235 Not Cancer Driver No 79 0.115 240 21 0.087 0
GRIK5_ENST00000593562 GRIK5 Q16478 Glutamate receptor ionotropic, kainate 5 chr19 GO:0051235 Not Cancer Driver No 176 0.18 135 9 0.067 0
GSN GSN P06396 Gelsolin chr9 GO:0051235 Not Cancer Driver No 76 0.097 316 28 0.089 2
HK1_ENST00000359426 HK1 P19367 Hexokinase-1 chr10 GO:0051235 Not Cancer Driver No 127 0.138 75 16 0.213 6
HK2 HK2 P52789 Hexokinase-2 chr2 GO:0051235 Not Cancer Driver No 138 0.15 77 7 0.091 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0051235 Not Cancer Driver No 77 0.093 504 45 0.089 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 GO:0051235 Not Cancer Driver No 73 0.112 282 35 0.124 0
IGSF11 IGSF11 Q5DX21 Immunoglobulin superfamily member 11 chr3 GO:0051235 Not Cancer Driver No 98 0.227 159 28 0.176 0
IL10 IL10 P22301 Interleukin-10 chr1 GO:0051235 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0051235 Not Cancer Driver No 39 0.145 16 3 0.188 0
INSIG1 INSIG1 O15503 Insulin-induced gene 1 protein chr7 GO:0051235 Not Cancer Driver No 37 0.134 43 1 0.023 0
INSIG2 INSIG2 Q9Y5U4 Insulin-induced gene 2 protein chr2 GO:0051235 Not Cancer Driver No 47 0.209 11 3 0.273 0
KDELR1 KDELR1 P24390 ER lumen protein-retaining receptor 1 chr19 GO:0051235 Not Cancer Driver No 32 0.151 0 0 0.0 0
KDELR2 KDELR2 P33947 ER lumen protein-retaining receptor 2 chr7 GO:0051235 Not Cancer Driver No 23 0.108 0 0 0.0 1
KDELR3_ENST00000216014 KDELR3 O43731 ER lumen protein-retaining receptor 3 chr22 GO:0051235 Not Cancer Driver No 22 0.103 0 0 0.0 0
KEAP1_ENST00000393623 KEAP1 Q14145 Kelch-like ECH-associated protein 1 chr19 GO:0051235 Census, Compendium Yes 237 0.38 57 12 0.211 0
LATS1 LATS1 O95835 Serine/threonine-protein kinase LATS1 chr6 GO:0051235 Census, Compendium Yes 161 0.142 788 100 0.127 0
LCN2_ENST00000277480 LCN2 P80188 Neutrophil gelatinase-associated lipocalin chr9 GO:0051235 Not Cancer Driver No 29 0.146 4 3 0.75 0
LTBP1 LTBP1 Q14766 Latent-transforming growth factor beta-binding protein 1 chr2 GO:0051235 Not Cancer Driver No 300 0.174 518 78 0.151 0
MDFI MDFI Q99750 MyoD family inhibitor chr6 GO:0051235 Not Cancer Driver No 25 0.102 152 15 0.099 0
MORC3 MORC3 Q14149 MORC family CW-type zinc finger protein 3 chr21 GO:0051235 Not Cancer Driver No 113 0.12 394 45 0.114 0
NBL1_ENST00000602662 NBL1 P41271 Neuroblastoma suppressor of tumorigenicity 1 chr1 GO:0051235 Not Cancer Driver No 18 0.099 64 4 0.062 0
NFKBIA NFKBIA P25963 NF-kappa-B inhibitor alpha chr14 GO:0051235 Compendium Yes 37 0.117 102 9 0.088 1
NFKBIB NFKBIB Q15653 NF-kappa-B inhibitor beta chr19 GO:0051235 Not Cancer Driver No 42 0.118 223 29 0.13 0
NFKBIE NFKBIE O00221 NF-kappa-B inhibitor epsilon chr6 GO:0051235 Census, Compendium Yes 41 0.082 284 16 0.056 0
NR5A1 NR5A1 Q13285 Steroidogenic factor 1 chr9 GO:0051235 Not Cancer Driver No 60 0.13 133 29 0.218 24
NRROS NRROS Q86YC3 Transforming growth factor beta activator LRRC33 chr3 GO:0051235 Not Cancer Driver No 109 0.158 8 1 0.125 0
OS9 OS9 Q13438 Protein OS-9 chr12 GO:0051235 Not Cancer Driver No 72 0.108 451 49 0.109 0
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:0051235 Not Cancer Driver No 42 0.102 82 11 0.134 7
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0051235 Not Cancer Driver No 11 0.058 30 0 0.0 5
PDIA2 PDIA2 Q13087 Protein disulfide-isomerase A2 chr16 GO:0051235 Not Cancer Driver No 70 0.133 80 12 0.15 0
PFN4 PFN4 Q8NHR9 Profilin-4 chr2 GO:0051235 Not Cancer Driver No 17 0.132 0 0 0.0 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0051235 Not Cancer Driver No 57 0.098 99 13 0.131 23
PKD1 PKD1 P98161 Polycystin-1 chr16 GO:0051235 Not Cancer Driver No 393 0.091 690 66 0.096 92
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0051235 Not Cancer Driver No 113 0.117 375 35 0.093 10
PML PML P29590 Protein PML chr15 GO:0051235 Census, Compendium Yes 112 0.127 312 34 0.109 0
PSMD10 PSMD10 O75832 26S proteasome non-ATPase regulatory subunit 10 chrX GO:0051235 Not Cancer Driver No 20 0.088 53 5 0.094 0
RANGAP1_ENST00000356244 RANGAP1 P46060 Ran GTPase-activating protein 1 chr22 GO:0051235 Not Cancer Driver No 65 0.111 159 17 0.107 0
RER1 RER1 O15258 Protein RER1 chr1 GO:0051235 Not Cancer Driver No 18 0.092 15 3 0.2 0
RIT2 RIT2 Q99578 GTP-binding protein Rit2 chr18 GO:0051235 Not Cancer Driver No 74 0.341 29 11 0.379 0
S100A7_ENST00000368722 S100A7 P31151 Protein S100-A7 chr1 GO:0051235 Census Yes 39 0.386 28 14 0.5 0
S100A8 S100A8 P05109 Protein S100-A8 chr1 GO:0051235 Not Cancer Driver No 22 0.237 8 4 0.5 0
S100A9 S100A9 P06702 Protein S100-A9 chr1 GO:0051235 Not Cancer Driver No 18 0.158 76 7 0.092 0
SCIN SCIN Q9Y6U3 Scinderin chr7 GO:0051235 Not Cancer Driver No 100 0.14 170 35 0.206 0
SKP1_ENST00000517625 SKP1 P63208 S-phase kinase-associated protein 1 chr5 GO:0051235 Not Cancer Driver No 19 0.117 95 17 0.179 0
SLC18A2_ENST00000644641 SLC18A2 Q05940 Synaptic vesicular amine transporter chr10 GO:0051235 Not Cancer Driver No 105 0.204 23 7 0.304 1
SLC30A7_ENST00000357650 SLC30A7 Q8NEW0 Zinc transporter 7 chr1 GO:0051235 Not Cancer Driver No 32 0.085 46 2 0.043 0
SLC30A8 SLC30A8 Q8IWU4 Zinc transporter 8 chr8 GO:0051235 Not Cancer Driver No 115 0.312 25 9 0.36 0
SOAT1 SOAT1 P35610 Sterol O-acyltransferase 1 chr1 GO:0051235 Not Cancer Driver No 73 0.133 49 4 0.082 0
SORL1 SORL1 Q92673 Sortilin-related receptor chr11 GO:0051235 Not Cancer Driver No 374 0.169 87 10 0.115 0
SP100_ENST00000264052 SP100 P23497 Nuclear autoantigen Sp-100 chr2 GO:0051235 Not Cancer Driver No 136 0.155 680 101 0.149 0
SPOUT1 SPOUT1 Q5T280 Putative methyltransferase C9orf114 chr9 GO:0051235 Not Cancer Driver No 35 0.093 166 18 0.108 0
SRGN SRGN P10124 Serglycin chr10 GO:0051235 Not Cancer Driver No 25 0.158 87 13 0.149 0
SRI SRI P30626 Sorcin chr7 GO:0051235 Not Cancer Driver No 15 0.076 32 2 0.062 0
SUFU SUFU Q9UMX1 Suppressor of fused homolog chr10 GO:0051235 Census Yes 55 0.114 199 19 0.095 2
SUN1 SUN1 O94901 SUN domain-containing protein 1 chr7 GO:0051235 Not Cancer Driver No 109 0.139 246 26 0.106 0
SUN2_ENST00000405510 SUN2 Q9UH99 SUN domain-containing protein 2 chr22 GO:0051235 Not Cancer Driver No 74 0.103 214 18 0.084 0
SUPT7L SUPT7L O94864 STAGA complex 65 subunit gamma chr2 GO:0051235 Not Cancer Driver No 41 0.099 281 30 0.107 0
SYNE1 SYNE1 Q8NF91 Nesprin-1 chr6 GO:0051235 Not Cancer Driver No 1694 0.193 2530 530 0.209 2
TAF3 TAF3 Q5VWG9 Transcription initiation factor TFIID subunit 3 chr10 GO:0051235 Not Cancer Driver No 113 0.122 750 90 0.12 0
TAF8 TAF8 Q7Z7C8 Transcription initiation factor TFIID subunit 8 chr6 GO:0051235 Not Cancer Driver No 35 0.113 255 30 0.118 0
TAPT1 TAPT1 Q6NXT6 Transmembrane anterior posterior transformation protein 1 homolog chr4 GO:0051235 Not Cancer Driver No 47 0.083 131 12 0.092 1
TBCCD1 TBCCD1 Q9NVR7 TBCC domain-containing protein 1 chr3 GO:0051235 Not Cancer Driver No 68 0.122 42 8 0.19 0
TMSB10 TMSB10 P63313 Thymosin beta-10 chr2 GO:0051235 Not Cancer Driver No 2 0.045 44 2 0.045 0
TMSB15A TMSB15A P0CG34 Thymosin beta-15A chrX GO:0051235 Not Cancer Driver No 8 0.178 45 8 0.178 0
TMSB15B TMSB15B P0CG35 Thymosin beta-15B chrX GO:0051235 Not Cancer Driver No 7 0.156 45 7 0.156 0
TMSB4X_ENST00000380633 TMSB4X P62328 Thymosin beta-4 chrX GO:0051235 Census Yes 7 0.159 44 7 0.159 0
TMSB4Y TMSB4Y O14604 Thymosin beta-4, Y-chromosomal chrY GO:0051235 Not Cancer Driver No 1 0.023 44 1 0.023 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0051235 Not Cancer Driver No 24 0.103 45 3 0.067 0
TOPORS TOPORS Q9NS56 E3 ubiquitin-protein ligase Topors chr9 GO:0051235 Not Cancer Driver No 149 0.143 795 105 0.132 0
TSPO_ENST00000329563 TSPO P30536 Translocator protein chr22 GO:0051235 Not Cancer Driver No 5 0.03 1 0 0.0 0
TWF1_ENST00000395510 TWF1 Q12792 Twinfilin-1 chr12 GO:0051235 Not Cancer Driver No 50 0.143 52 3 0.058 0
TWF2 TWF2 Q6IBS0 Twinfilin-2 chr3 GO:0051235 Not Cancer Driver No 34 0.097 59 8 0.136 0
TXN TXN P10599 Thioredoxin chr9 GO:0051235 Not Cancer Driver No 6 0.057 0 0 0.0 0
UVRAG UVRAG Q9P2Y5 UV radiation resistance-associated gene protein chr11 GO:0051235 Not Cancer Driver No 89 0.127 243 28 0.115 0
VPS13A VPS13A Q96RL7 Intermembrane lipid transfer protein VPS13A chr9 GO:0051235 Not Cancer Driver No 375 0.118 208 18 0.087 6
VPS13C_ENST00000261517 VPS13C Q709C8 Intermembrane lipid transfer protein VPS13C chr15 GO:0051235 Not Cancer Driver No 446 0.119 433 51 0.118 1
VPS13D VPS13D Q5THJ4 Intermembrane lipid transfer protein VPS13D chr1 GO:0051235 Not Cancer Driver No 501 0.114 973 118 0.121 8
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 GO:0051235 Not Cancer Driver No 22 0.089 109 4 0.037 0