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Total number of protein in "GO:0051223" GO term:  394

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AACS AACS Q86V21 Acetoacetyl-CoA synthetase chr12 GO:0051223 Not Cancer Driver No 92 0.137 16 0 0.0 0
ABAT_ENST00000268251 ABAT P80404 4-aminobutyrate aminotransferase, mitochondrial chr16 GO:0051223 Not Cancer Driver No 84 0.168 28 5 0.179 1
ABCA12 ABCA12 Q86UK0 Glucosylceramide transporter ABCA12 chr2 GO:0051223 Not Cancer Driver No 511 0.197 136 23 0.169 14
ABCC8_ENST00000389817 ABCC8 Q09428 ATP-binding cassette sub-family C member 8 chr11 GO:0051223 Not Cancer Driver No 255 0.161 138 23 0.167 97
ABLIM3_ENST00000309868 ABLIM3 O94929 Actin-binding LIM protein 3 chr5 GO:0051223 Not Cancer Driver No 125 0.183 282 62 0.22 0
ACSL3 ACSL3 O95573 Fatty acid CoA ligase Acsl3 chr2 GO:0051223 Census, Compendium Yes 89 0.124 47 7 0.149 0
ACSL4_ENST00000469796 ACSL4 O60488 Long-chain-fatty-acid--CoA ligase 4 chrX GO:0051223 Not Cancer Driver No 97 0.136 77 12 0.156 1
ACVR1C ACVR1C Q8NER5 Activin receptor type-1C chr2 GO:0051223 Not Cancer Driver No 90 0.183 3 1 0.333 0
ADCY5 ADCY5 O95622 Adenylate cyclase type 5 chr3 GO:0051223 Not Cancer Driver No 234 0.186 268 23 0.086 2
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0051223 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0051223 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADRA2A ADRA2A P08913 Alpha-2A adrenergic receptor chr10 GO:0051223 Not Cancer Driver No 67 0.144 161 10 0.062 0
ADTRP_ENST00000414691 ADTRP Q96IZ2 Androgen-dependent TFPI-regulating protein chr6 GO:0051223 Not Cancer Driver No 41 0.178 2 0 0.0 0
AKAP5_ENST00000320636 AKAP5 P24588 A-kinase anchor protein 5 chr14 GO:0051223 Not Cancer Driver No 37 0.087 405 34 0.084 0
AKT2 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 GO:0051223 Census Yes 77 0.16 84 9 0.107 2
AL132671.2 AL132671.2 A0A0J9YVX5 Uncharacterized protein (Fragment) chr6 GO:0051223 Not Cancer Driver No 54 0.174 128 26 0.203 0
ANGPT1 ANGPT1 Q15389 Angiopoietin-1 chr8 GO:0051223 Not Cancer Driver No 130 0.261 131 24 0.183 1
ANK3 ANK3 Q12955 Ankyrin-3 chr10 GO:0051223 Not Cancer Driver No 860 0.196 3054 579 0.19 0
ANO1 ANO1 Q5XXA6 Anoctamin-1 chr11 GO:0051223 Not Cancer Driver No 155 0.157 168 14 0.083 0
ANP32B ANP32B Q92688 Acidic leucine-rich nuclear phosphoprotein 32 family member B chr9 GO:0051223 Not Cancer Driver No 22 0.088 117 12 0.103 0
APOD APOD P05090 Apolipoprotein D chr3 GO:0051223 Not Cancer Driver No 34 0.18 13 2 0.154 0
APOE APOE P02649 Apolipoprotein E chr19 GO:0051223 Not Cancer Driver No 25 0.079 124 6 0.048 12
ARHGAP44 ARHGAP44 Q17R89 Rho GTPase-activating protein 44 chr17 GO:0051223 Not Cancer Driver No 126 0.154 424 67 0.158 0
ARHGEF5 ARHGEF5 Q12774 Rho guanine nucleotide exchange factor 5 chr7 GO:0051223 Not Cancer Driver No 170 0.106 1141 127 0.111 0
ARIH2 ARIH2 O95376 E3 ubiquitin-protein ligase ARIH2 chr3 GO:0051223 Not Cancer Driver No 64 0.13 85 11 0.129 0
ATG13_ENST00000359513 ATG13 O75143 Autophagy-related protein 13 chr11 GO:0051223 Not Cancer Driver No 55 0.106 205 27 0.132 0
ATP13A2 ATP13A2 Q9NQ11 Polyamine-transporting ATPase 13A2 chr1 GO:0051223 Not Cancer Driver No 152 0.129 121 10 0.083 9
ATP2C1_ENST00000508532 ATP2C1 P98194 Calcium-transporting ATPase type 2C member 1 chr3 GO:0051223 Not Cancer Driver No 125 0.136 44 5 0.114 20
ATP5IF1 ATP5IF1 Q9UII2 ATPase inhibitor, mitochondrial chr1 GO:0051223 Not Cancer Driver No 8 0.075 85 7 0.082 0
B3GAT3 B3GAT3 O94766 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 chr11 GO:0051223 Not Cancer Driver No 42 0.125 139 17 0.122 2
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0051223 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 GO:0051223 Not Cancer Driver No 57 0.099 571 57 0.1 7
BAG4 BAG4 O95429 BAG family molecular chaperone regulator 4 chr8 GO:0051223 Not Cancer Driver No 55 0.12 402 49 0.122 0
BAIAP3 BAIAP3 O94812 BAI1-associated protein 3 chr16 GO:0051223 Not Cancer Driver No 170 0.143 230 35 0.152 0
BAP1 BAP1 Q92560 Ubiquitin carboxyl-terminal hydrolase BAP1 chr3 GO:0051223 Census, Compendium Yes 141 0.193 418 59 0.141 0
BARD1 BARD1 Q99728 BRCA1-associated RING domain protein 1 chr2 GO:0051223 Census Yes 96 0.124 384 49 0.128 0
BBC3 BBC3 Q96PG8 Bcl-2-binding component 3, isoforms 3/4 chr19 GO:0051223 Not Cancer Driver No 20 0.077 253 20 0.079 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX GO:0051223 Not Cancer Driver No 37 0.15 104 14 0.135 0
BCAS3_ENST00000390652 BCAS3 Q9H6U6 BCAS3 microtubule associated cell migration factor chr17 GO:0051223 Not Cancer Driver No 134 0.144 417 67 0.161 0
BLK BLK P51451 Tyrosine-protein kinase Blk chr8 GO:0051223 Not Cancer Driver No 94 0.186 75 21 0.28 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0051223 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMP8A BMP8A Q7Z5Y6 Bone morphogenetic protein 8A chr1 GO:0051223 Not Cancer Driver No 26 0.065 93 2 0.022 0
BNIP3L BNIP3L O60238 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like chr8 GO:0051223 Not Cancer Driver No 16 0.073 175 14 0.08 0
BRSK2_ENST00000528841 BRSK2 Q8IWQ3 Serine/threonine-protein kinase BRSK2 chr11 GO:0051223 Not Cancer Driver No 90 0.122 321 39 0.121 0
C11orf65 MFI Q8NCR3 Protein MFI chr11 GO:0051223 Not Cancer Driver No 42 0.134 66 7 0.106 0
C1QTNF12 C1QTNF12 Q5T7M4 Adipolin chr1 GO:0051223 Not Cancer Driver No 13 0.043 105 5 0.048 0
C1QTNF3_ENST00000231338 C1QTNF3 Q9BXJ4 Complement C1q tumor necrosis factor-related protein 3 chr5 GO:0051223 Not Cancer Driver No 42 0.171 73 14 0.192 0
C2CD2L C2CD2L O14523 Phospholipid transfer protein C2CD2L chr11 GO:0051223 Not Cancer Driver No 77 0.109 491 65 0.132 0
C2CD5_ENST00000333957 C2CD5 Q86YS7 C2 domain-containing protein 5 chr12 GO:0051223 Not Cancer Driver No 136 0.136 250 40 0.16 0
CABP1 CABP1 Q9NZU7 Calcium-binding protein 1 chr12 GO:0051223 Not Cancer Driver No 31 0.084 271 14 0.052 0
CAMK1 CAMK1 Q14012 Calcium/calmodulin-dependent protein kinase type 1 chr3 GO:0051223 Not Cancer Driver No 40 0.108 31 1 0.032 0
CAPN10 CAPN10 Q9HC96 Calpain-10 chr2 GO:0051223 Not Cancer Driver No 87 0.129 52 6 0.115 0
CASR_ENST00000638421 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0051223 Not Cancer Driver No 304 0.282 189 60 0.317 108
CCN3 CCN3 P48745 CCN family member 3 chr8 GO:0051223 Not Cancer Driver No 66 0.185 19 1 0.053 0
CD200_ENST00000315711 CD200 P41217 OX-2 membrane glycoprotein chr3 GO:0051223 Not Cancer Driver No 37 0.133 14 0 0.0 0
CD36_ENST00000309881 CD36 P16671 Platelet glycoprotein 4 chr7 GO:0051223 Not Cancer Driver No 75 0.159 12 3 0.25 3
CD38 CD38 P28907 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 chr4 GO:0051223 Not Cancer Driver No 54 0.18 3 1 0.333 0
CD81 CD81 P60033 CD81 antigen chr11 GO:0051223 Not Cancer Driver No 28 0.119 0 0 0.0 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0051223 Not Cancer Driver No 39 0.204 23 2 0.087 1
CDH1 CDH1 P12830 Cadherin-1 chr16 GO:0051223 Census, Compendium Yes 150 0.17 400 82 0.205 5
CDK1 CDK1 P06493 Cyclin-dependent kinase 1 chr10 GO:0051223 Not Cancer Driver No 40 0.135 1 0 0.0 0
CDK16_ENST00000357227 CDK16 Q00536 Cyclin-dependent kinase 16 chrX GO:0051223 Not Cancer Driver No 55 0.111 139 30 0.216 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0051223 Not Cancer Driver No 48 0.164 5 1 0.2 0
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:0051223 Not Cancer Driver No 35 0.114 103 16 0.155 0
CEMIP_ENST00000356249 CEMIP Q8WUJ3 Cell migration-inducing and hyaluronan-binding protein chr15 GO:0051223 Not Cancer Driver No 207 0.152 105 10 0.095 0
CEP131 CEP131 Q9UPN4 Centrosomal protein of 131 kDa chr17 GO:0051223 Not Cancer Driver No 126 0.116 948 113 0.119 0
CEP290 CEP290 O15078 Centrosomal protein of 290 kDa chr12 GO:0051223 Not Cancer Driver No 255 0.103 1421 152 0.107 3
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 GO:0051223 Not Cancer Driver No 287 0.194 145 18 0.124 151
CHGA CHGA P10645 Chromogranin-A chr14 GO:0051223 Not Cancer Driver No 46 0.101 421 44 0.105 0
CHP1 CHP1 Q99653 Calcineurin B homologous protein 1 chr15 GO:0051223 Not Cancer Driver No 27 0.138 70 12 0.171 0
CHP2 CHP2 O43745 Calcineurin B homologous protein 2 chr16 GO:0051223 Not Cancer Driver No 43 0.219 65 16 0.246 0
CHRM1 CHRM1 P11229 Muscarinic acetylcholine receptor M1 chr11 GO:0051223 Not Cancer Driver No 63 0.137 131 24 0.183 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0051223 Not Cancer Driver No 24 0.126 6 1 0.167 0
CLN3_ENST00000636147 CLN3 Q13286 Battenin chr16 GO:0051223 Not Cancer Driver No 58 0.132 69 10 0.145 9
CNST CNST Q6PJW8 Consortin chr1 GO:0051223 Not Cancer Driver No 113 0.156 499 82 0.164 0
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 GO:0051223 Not Cancer Driver No 41 0.091 18 1 0.056 0
CSNK2A2 CSNK2A2 P19784 Casein kinase II subunit alpha' chr16 GO:0051223 Not Cancer Driver No 43 0.123 13 1 0.077 0
CTDSPL2 CTDSPL2 Q05D32 CTD small phosphatase-like protein 2 chr15 GO:0051223 Not Cancer Driver No 47 0.101 256 27 0.105 0
CYP51A1 CYP51A1 Q16850 Lanosterol 14-alpha demethylase chr7 GO:0051223 Not Cancer Driver No 49 0.096 7 2 0.286 0
DERL2 DERL2 Q9GZP9 Derlin-2 chr17 GO:0051223 Not Cancer Driver No 19 0.079 15 1 0.067 0
DERL3_ENST00000318109 DERL3 Q96Q80 Derlin-3 chr22 GO:0051223 Not Cancer Driver No 18 0.077 18 1 0.056 0
DMAP1_ENST00000315913 DMAP1 Q9NPF5 DNA methyltransferase 1-associated protein 1 chr1 GO:0051223 Not Cancer Driver No 49 0.105 269 28 0.104 0
DMTN_ENST00000358242 DMTN Q08495 Dematin chr8 GO:0051223 Not Cancer Driver No 53 0.131 348 46 0.132 0
DNAJA1 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 GO:0051223 Not Cancer Driver No 37 0.093 153 16 0.105 0
DNAJC27 DNAJC27 Q9NZQ0 DnaJ homolog subfamily C member 27 chr2 GO:0051223 Not Cancer Driver No 33 0.121 36 4 0.111 0
DOC2B DOC2B Q14184 Double C2-like domain-containing protein beta chr17 GO:0051223 Not Cancer Driver No 10 0.024 197 3 0.015 0
DPH3 DPH3 Q96FX2 DPH3 homolog chr3 GO:0051223 Not Cancer Driver No 12 0.146 0 0 0.0 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0051223 Not Cancer Driver No 127 0.287 124 45 0.363 0
DRD3_ENST00000460779 DRD3 P35462 D(3) dopamine receptor chr3 GO:0051223 Not Cancer Driver No 88 0.22 45 17 0.378 0
DRD4 DRD4 P21917 D(4) dopamine receptor chr11 GO:0051223 Not Cancer Driver No 26 0.062 109 0 0.0 0
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 GO:0051223 Not Cancer Driver No 104 0.114 284 33 0.116 0
EDEM1 EDEM1 Q92611 ER degradation-enhancing alpha-mannosidase-like protein 1 chr3 GO:0051223 Not Cancer Driver No 54 0.082 141 5 0.035 0
EDEM2 EDEM2 Q9BV94 ER degradation-enhancing alpha-mannosidase-like protein 2 chr20 GO:0051223 Not Cancer Driver No 69 0.119 54 3 0.056 0
EFCAB7 EFCAB7 A8K855 EF-hand calcium-binding domain-containing protein 7 chr1 GO:0051223 Not Cancer Driver No 78 0.124 97 17 0.175 0
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0051223 Not Cancer Driver No 34 0.149 25 6 0.24 0
EMD EMD P50402 Emerin chrX GO:0051223 Not Cancer Driver No 42 0.165 160 28 0.175 4
EPHA5_ENST00000273854 EPHA5 P54756 Ephrin type-A receptor 5 chr4 GO:0051223 Not Cancer Driver No 341 0.329 83 39 0.47 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0051223 Census, Compendium Yes 275 0.219 314 41 0.131 1
ERGIC3_ENST00000348547 ERGIC3 Q9Y282 Endoplasmic reticulum-Golgi intermediate compartment protein 3 chr20 GO:0051223 Not Cancer Driver No 53 0.138 23 3 0.13 0
ERLEC1 ERLEC1 Q96DZ1 Endoplasmic reticulum lectin 1 chr2 GO:0051223 Not Cancer Driver No 54 0.112 134 17 0.127 0
ERP29 ERP29 P30040 Endoplasmic reticulum resident protein 29 chr12 GO:0051223 Not Cancer Driver No 29 0.111 34 5 0.147 0
F2R F2R P25116 Proteinase-activated receptor 1 chr5 GO:0051223 Not Cancer Driver No 73 0.172 19 2 0.105 0
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0051223 Not Cancer Driver No 55 0.139 7 2 0.286 0
FAM3D FAM3D Q96BQ1 Protein FAM3D chr3 GO:0051223 Not Cancer Driver No 43 0.192 16 4 0.25 0
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 GO:0051223 Census, Compendium Yes 322 0.455 230 38 0.165 0
FERMT1 FERMT1 Q9BQL6 Fermitin family homolog 1 chr20 GO:0051223 Not Cancer Driver No 100 0.148 65 8 0.123 2
FFAR1 FFAR1 O14842 Free fatty acid receptor 1 chr19 GO:0051223 Not Cancer Driver No 45 0.15 2 0 0.0 0
FIS1 FIS1 Q9Y3D6 Mitochondrial fission 1 protein chr7 GO:0051223 Not Cancer Driver No 25 0.164 6 0 0.0 0
FKBP1B FKBP1B P68106 Peptidyl-prolyl cis-trans isomerase FKBP1B chr2 GO:0051223 Not Cancer Driver No 10 0.093 58 4 0.069 0
FLNA FLNA P21333 Filamin-A chrX GO:0051223 Census Yes 416 0.157 1456 214 0.147 28
FOXA2_ENST00000377115 FOXA2 Q9Y261 Hepatocyte nuclear factor 3-beta chr20 GO:0051223 Compendium Yes 70 0.153 258 34 0.132 0
FRAT1 FRAT1 Q92837 Proto-oncogene FRAT1 chr10 GO:0051223 Not Cancer Driver No 6 0.022 266 6 0.023 0
FRMD4A FRMD4A Q9P2Q2 FERM domain-containing protein 4A chr10 GO:0051223 Not Cancer Driver No 122 0.117 666 72 0.108 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0051223 Not Cancer Driver No 92 0.171 70 13 0.186 0
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:0051223 Not Cancer Driver No 45 0.077 58 4 0.069 0
GAPVD1_ENST00000495955 GAPVD1 Q14C86 GTPase-activating protein and VPS9 domain-containing protein 1 chr9 GO:0051223 Not Cancer Driver No 188 0.127 705 93 0.132 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0051223 Not Cancer Driver No 82 0.121 42 6 0.143 0
GCC2 GCC2 Q8IWJ2 GRIP and coiled-coil domain-containing protein 2 chr2 GO:0051223 Not Cancer Driver No 178 0.106 999 113 0.113 0
GCG GCG P01275 Pro-glucagon chr2 GO:0051223 Not Cancer Driver No 49 0.272 82 22 0.268 0
GCK_ENST00000403799 GCK P35557 Hexokinase-4 chr7 GO:0051223 Not Cancer Driver No 88 0.189 73 14 0.192 107
GDI1 GDI1 P31150 Rab GDP dissociation inhibitor alpha chrX GO:0051223 Not Cancer Driver No 69 0.154 34 6 0.176 2
GHRL_ENST00000457360 GHRL Q9UBU3 Appetite-regulating hormone chr3 GO:0051223 Not Cancer Driver No 20 0.171 52 11 0.212 0
GHSR GHSR Q92847 Growth hormone secretagogue receptor type 1 chr3 GO:0051223 Not Cancer Driver No 85 0.232 4 0 0.0 2
GIP GIP P09681 Gastric inhibitory polypeptide chr17 GO:0051223 Not Cancer Driver No 35 0.229 68 16 0.235 0
GIPR GIPR P48546 Gastric inhibitory polypeptide receptor chr19 GO:0051223 Not Cancer Driver No 45 0.097 41 0 0.0 0
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0051223 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GLUD1 GLUD1 P00367 Glutamate dehydrogenase 1, mitochondrial chr10 GO:0051223 Not Cancer Driver No 50 0.09 107 14 0.131 13
GLUL_ENST00000331872 GLUL P15104 Glutamine synthetase chr1 GO:0051223 Not Cancer Driver No 66 0.177 104 21 0.202 2
GOPC GOPC Q9HD26 Golgi-associated PDZ and coiled-coil motif-containing protein chr6 GO:0051223 Census Yes 56 0.121 263 34 0.129 0
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0051223 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0051223 Not Cancer Driver No 153 0.182 36 9 0.25 0
GPR27 GPR27 Q9NS67 Probable G-protein coupled receptor 27 chr3 GO:0051223 Not Cancer Driver No 26 0.069 23 1 0.043 0
GPR68_ENST00000535815 GPR68 Q15743 Ovarian cancer G-protein coupled receptor 1 chr14 GO:0051223 Not Cancer Driver No 42 0.115 45 1 0.022 1
GRASP TAMALIN Q7Z6J2 Protein TAMALIN chr12 GO:0051223 Not Cancer Driver No 24 0.061 234 14 0.06 0
GRIPAP1 GRIPAP1 Q4V328 GRIP1-associated protein 1 chrX GO:0051223 Not Cancer Driver No 110 0.131 725 99 0.137 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0051223 Not Cancer Driver No 55 0.114 180 8 0.044 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0051223 Not Cancer Driver No 56 0.133 146 13 0.089 0
GZMB GZMB P10144 Granzyme B chr14 GO:0051223 Not Cancer Driver No 49 0.198 103 23 0.223 0
HADH_ENST00000309522 HADH Q16836 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial chr4 GO:0051223 Not Cancer Driver No 33 0.105 22 5 0.227 3
HAX1 HAX1 O00165 HCLS1-associated protein X-1 chr1 GO:0051223 Not Cancer Driver No 44 0.158 219 32 0.146 2
HCAR2 HCAR2 Q8TDS4 Hydroxycarboxylic acid receptor 2 chr12 GO:0051223 Not Cancer Driver No 78 0.215 43 8 0.186 0
HCLS1 HCLS1 P14317 Hematopoietic lineage cell-specific protein chr3 GO:0051223 Not Cancer Driver No 103 0.212 446 94 0.211 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 GO:0051223 Not Cancer Driver No 65 0.152 61 8 0.131 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0051223 Census Yes 118 0.143 435 51 0.117 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0051223 Not Cancer Driver No 48 0.18 12 1 0.083 0
HMGCR_ENST00000511206 HMGCR P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase chr5 GO:0051223 Not Cancer Driver No 84 0.095 112 12 0.107 0
HMGN3_ENST00000344726 HMGN3 Q15651 High mobility group nucleosome-binding domain-containing protein 3 chr6 GO:0051223 Not Cancer Driver No 14 0.141 99 14 0.141 0
HPCA HPCA P84074 Neuron-specific calcium-binding protein hippocalcin chr1 GO:0051223 Not Cancer Driver No 24 0.124 42 4 0.095 3
HPS4_ENST00000336873 HPS4 Q9NQG7 Hermansky-Pudlak syndrome 4 protein chr22 GO:0051223 Not Cancer Driver No 96 0.136 343 57 0.166 0
HRAS HRAS P01112 GTPase HRas chr11 GO:0051223 Census, Compendium Yes 107 0.566 16 4 0.25 18
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0051223 Census, Compendium Yes 100 0.138 254 43 0.169 0
HSPA1L HSPA1L P34931 Heat shock 70 kDa protein 1-like chr6 GO:0051223 Not Cancer Driver No 119 0.186 141 28 0.199 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 GO:0051223 Not Cancer Driver No 149 0.231 251 52 0.207 0
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 GO:0051223 Compendium Yes 44 0.096 127 9 0.071 2
HUWE1_ENST00000262854 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX GO:0051223 Not Cancer Driver No 669 0.153 2091 329 0.157 21
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:0051223 Not Cancer Driver No 52 0.11 8 1 0.125 0
ICE1 ICE1 Q9Y2F5 Little elongation complex subunit 1 chr5 GO:0051223 Not Cancer Driver No 360 0.159 1666 265 0.159 0
IFI27_ENST00000621160 IFI27 P40305 Interferon alpha-inducible protein 27, mitochondrial chr14 GO:0051223 Not Cancer Driver No 10 0.082 0 0 0.0 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0051223 Not Cancer Driver No 51 0.307 23 6 0.261 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0051223 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0051223 Not Cancer Driver No 39 0.145 16 3 0.188 0
INHBB INHBB P09529 Inhibin beta B chain chr2 GO:0051223 Not Cancer Driver No 61 0.15 98 5 0.051 0
INPP5K INPP5K Q9BT40 Inositol polyphosphate 5-phosphatase K chr17 GO:0051223 Not Cancer Driver No 42 0.094 34 2 0.059 7
INS INS P01308 Insulin chr11 GO:0051223 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSIG1 INSIG1 O15503 Insulin-induced gene 1 protein chr7 GO:0051223 Not Cancer Driver No 37 0.134 43 1 0.023 0
IPO5_ENST00000490680 IPO5 O00410 Importin-5 chr13 GO:0051223 Not Cancer Driver No 128 0.117 52 3 0.058 0
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 GO:0051223 Not Cancer Driver No 161 0.13 1072 133 0.124 2
IRS2 IRS2 Q9Y4H2 Insulin receptor substrate 2 chr13 GO:0051223 Not Cancer Driver No 69 0.052 1112 57 0.051 0
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0051223 Not Cancer Driver No 85 0.244 180 41 0.228 0
ITGAM_ENST00000287497 ITGAM P11215 Integrin alpha-M chr16 GO:0051223 Not Cancer Driver No 191 0.166 133 12 0.09 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0051223 Not Cancer Driver No 26 0.13 58 11 0.19 0
ITGB2_ENST00000355153 ITGB2 P05107 Integrin beta-2 chr21 GO:0051223 Not Cancer Driver No 147 0.191 59 9 0.153 15
JAGN1 JAGN1 Q8N5M9 Protein jagunal homolog 1 chr3 GO:0051223 Not Cancer Driver No 21 0.115 12 2 0.167 5
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0051223 Census, Compendium Yes 136 0.12 59 5 0.085 5
JUP JUP P14923 Junction plakoglobin chr17 GO:0051223 Not Cancer Driver No 112 0.15 241 37 0.154 0
KCNB1_ENST00000635465 KCNB1 Q14721 Potassium voltage-gated channel subfamily B member 1 chr20 GO:0051223 Not Cancer Driver No 192 0.224 417 100 0.24 6
KCNE1_ENST00000399284 KCNE1 P15382 Potassium voltage-gated channel subfamily E member 1 chr21 GO:0051223 Not Cancer Driver No 35 0.271 24 10 0.417 9
KCNJ11 KCNJ11 Q14654 ATP-sensitive inward rectifier potassium channel 11 chr11 GO:0051223 Not Cancer Driver No 48 0.123 19 3 0.158 46
KIF20B KIF20B Q96Q89 Kinesin-like protein KIF20B chr10 GO:0051223 Not Cancer Driver No 217 0.119 902 109 0.121 0
KLF7 KLF7 O75840 Krueppel-like factor 7 chr2 GO:0051223 Not Cancer Driver No 46 0.152 72 7 0.097 0
LCP1 LCP1 P13796 Plastin-2 chr13 GO:0051223 Census Yes 99 0.158 73 11 0.151 0
LEP LEP P41159 Leptin chr7 GO:0051223 Not Cancer Driver No 29 0.174 0 0 0.0 2
LEPROT_ENST00000371065 LEPROT O15243 Leptin receptor gene-related protein chr1 GO:0051223 Not Cancer Driver No 16 0.122 0 0 0.0 0
LMAN1 LMAN1 P49257 Protein ERGIC-53 chr18 GO:0051223 Not Cancer Driver No 63 0.124 222 25 0.113 1
LRP5 LRP5 O75197 Low-density lipoprotein receptor-related protein 5 chr11 GO:0051223 Not Cancer Driver No 253 0.157 188 28 0.149 55
LRP5L_ENST00000402785 LRP5L A4QPB2 Low-density lipoprotein receptor-related protein 5-like protein chr22 GO:0051223 Not Cancer Driver No 38 0.151 39 5 0.128 0
LRRC8A_ENST00000372599 LRRC8A Q8IWT6 Volume-regulated anion channel subunit LRRC8A chr9 GO:0051223 Not Cancer Driver No 105 0.13 32 3 0.094 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0051223 Not Cancer Driver No 519 0.205 90 17 0.189 23
LYPLA1 LYPLA1 O75608 Acyl-protein thioesterase 1 chr8 GO:0051223 Not Cancer Driver No 19 0.083 12 2 0.167 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0051223 Not Cancer Driver No 39 0.108 25 1 0.04 0
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 GO:0051223 Not Cancer Driver No 64 0.15 94 9 0.096 0
MAVS MAVS Q7Z434 Mitochondrial antiviral-signaling protein chr20 GO:0051223 Not Cancer Driver No 70 0.13 411 58 0.141 0
MCU MCU Q8NE86 Calcium uniporter protein, mitochondrial chr10 GO:0051223 Not Cancer Driver No 41 0.117 13 0 0.0 0
MDFIC_ENST00000393486 MDFIC Q9P1T7 MyoD family inhibitor domain-containing protein chr7 GO:0051223 Not Cancer Driver No 35 0.142 143 23 0.161 0
MFF MFF Q9GZY8 Mitochondrial fission factor chr2 GO:0051223 Not Cancer Driver No 59 0.173 264 47 0.178 0
MICALL2 MICALL2 Q8IY33 MICAL-like protein 2 chr7 GO:0051223 Not Cancer Driver No 110 0.122 675 88 0.13 0
MIDN MIDN Q504T8 Midnolin chr19 GO:0051223 Not Cancer Driver No 43 0.092 446 43 0.096 0
MIEF1_ENST00000404569 MIEF1 Q9NQG6 Mitochondrial dynamics protein MID51 chr22 GO:0051223 Not Cancer Driver No 65 0.14 94 9 0.096 0
MIEF2_ENST00000323019 MIEF2 Q96C03 Mitochondrial dynamics protein MID49 chr17 GO:0051223 Not Cancer Driver No 43 0.095 89 9 0.101 0
MPC2 MPC2 O95563 Mitochondrial pyruvate carrier 2 chr1 GO:0051223 Not Cancer Driver No 13 0.102 0 0 0.0 0
MTCL1_ENST00000306329 MTCL1 Q9Y4B5 Microtubule cross-linking factor 1 chr18 GO:0051223 Not Cancer Driver No 267 0.14 1681 232 0.138 0
MTNR1B MTNR1B P49286 Melatonin receptor type 1B chr11 GO:0051223 Not Cancer Driver No 104 0.287 8 1 0.125 0
MYO1C MYO1C O00159 Unconventional myosin-Ic chr17 GO:0051223 Not Cancer Driver No 110 0.103 66 11 0.167 0
MYRIP MYRIP Q8NFW9 Rab effector MyRIP chr3 GO:0051223 Not Cancer Driver No 133 0.155 599 95 0.159 0
NDEL1 NDEL1 Q9GZM8 Nuclear distribution protein nudE-like 1 chr17 GO:0051223 Not Cancer Driver No 32 0.093 202 16 0.079 0
NDFIP1 NDFIP1 Q9BT67 NEDD4 family-interacting protein 1 chr5 GO:0051223 Not Cancer Driver No 22 0.1 44 4 0.091 0
NDFIP2_ENST00000218652 NDFIP2 Q9NV92 NEDD4 family-interacting protein 2 chr13 GO:0051223 Not Cancer Driver No 27 0.08 198 13 0.066 0
NDUFAF2 NDUFAF2 Q8N183 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 chr5 GO:0051223 Not Cancer Driver No 21 0.124 116 13 0.112 0
NF1 NF1 P21359 Neurofibromin chr17 GO:0051223 Census, Compendium Yes 375 0.132 406 47 0.116 85
NKX6-1 NKX6-1 P78426 Homeobox protein Nkx-6.1 chr4 GO:0051223 Not Cancer Driver No 38 0.104 325 34 0.105 0
NLGN2 NLGN2 Q8NFZ4 Neuroligin-2 chr17 GO:0051223 Not Cancer Driver No 91 0.109 300 19 0.063 0
NMT1_ENST00000258960 NMT1 P30419 Glycylpeptide N-tetradecanoyltransferase 1 chr17 GO:0051223 Not Cancer Driver No 62 0.125 169 22 0.13 0
NNAT NNAT Q16517 Neuronatin chr20 GO:0051223 Not Cancer Driver No 9 0.111 8 0 0.0 0
NOLC1_ENST00000605788 NOLC1 Q14978 Nucleolar and coiled-body phosphoprotein 1 chr10 GO:0051223 Not Cancer Driver No 74 0.106 662 69 0.104 0
NPEPPS NPEPPS P55786 Puromycin-sensitive aminopeptidase chr17 GO:0051223 Compendium Yes 102 0.111 45 5 0.111 0
NR0B2 NR0B2 Q15466 Nuclear receptor subfamily 0 group B member 2 chr1 GO:0051223 Not Cancer Driver No 35 0.136 10 2 0.2 0
NR1D1 NR1D1 P20393 Nuclear receptor subfamily 1 group D member 1 chr17 GO:0051223 Not Cancer Driver No 81 0.132 348 49 0.141 0
NR1H2_ENST00000593926 NR1H2 P55055 Oxysterols receptor LXR-beta chr19 GO:0051223 Not Cancer Driver No 56 0.122 179 30 0.168 0
NR1H3_ENST00000467728 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 GO:0051223 Not Cancer Driver No 56 0.125 146 13 0.089 0
NR1H4 NR1H4 Q96RI1 Bile acid receptor chr12 GO:0051223 Not Cancer Driver No 111 0.228 78 18 0.231 0
NUP54 NUP54 Q7Z3B4 Nucleoporin p54 chr4 GO:0051223 Not Cancer Driver No 42 0.083 233 25 0.107 0
NUP58 NUP58 Q9BVL2 Nucleoporin p58/p45 chr13 GO:0051223 Not Cancer Driver No 76 0.127 377 49 0.13 0
OAZ1 OAZ1 P54368 Ornithine decarboxylase antizyme 1 chr19 GO:0051223 Not Cancer Driver No 30 0.132 109 12 0.11 0
OAZ2 OAZ2 O95190 Ornithine decarboxylase antizyme 2 chr15 GO:0051223 Not Cancer Driver No 15 0.079 11 0 0.0 0
OAZ3_ENST00000639906 OAZ3 Q9UMX2 Ornithine decarboxylase antizyme 3 chr1 GO:0051223 Not Cancer Driver No 37 0.157 33 2 0.061 0
OPRM1_ENST00000330432 OPRM1 P35372 Mu-type opioid receptor chr6 GO:0051223 Not Cancer Driver No 107 0.268 58 27 0.466 0
OR51E2_ENST00000641638 OR51E2 Q9H255 Olfactory receptor 51E2 chr11 GO:0051223 Not Cancer Driver No 108 0.338 0 0 0.0 0
OS9 OS9 Q13438 Protein OS-9 chr12 GO:0051223 Not Cancer Driver No 72 0.108 451 49 0.109 0
OSBP OSBP P22059 Oxysterol-binding protein 1 chr11 GO:0051223 Not Cancer Driver No 83 0.103 386 39 0.101 0
OXCT1 OXCT1 P55809 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial chr5 GO:0051223 Not Cancer Driver No 80 0.154 39 5 0.128 11
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0051223 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARL PARL Q9H300 Presenilins-associated rhomboid-like protein, mitochondrial chr3 GO:0051223 Not Cancer Driver No 49 0.129 28 5 0.179 0
PCK2 PCK2 Q16822 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial chr14 GO:0051223 Not Cancer Driver No 91 0.142 139 13 0.094 0
PCM1 PCM1 Q15154 Pericentriolar material 1 protein chr8 GO:0051223 Census Yes 152 0.075 1665 134 0.08 0
PCNT PCNT O95613 Pericentrin chr21 GO:0051223 Not Cancer Driver No 436 0.131 2474 337 0.136 0
PDCD10_ENST00000473645 PDCD10 Q9BUL8 Programmed cell death protein 10 chr3 GO:0051223 Not Cancer Driver No 32 0.151 25 4 0.16 0
PDCD5 PDCD5 O14737 Programmed cell death protein 5 chr19 GO:0051223 Not Cancer Driver No 15 0.12 91 7 0.077 0
PDX1 PDX1 P52945 Pancreas/duodenum homeobox protein 1 chr13 GO:0051223 Not Cancer Driver No 32 0.113 238 23 0.097 0
PDZK1_ENST00000344770 PDZK1 Q5T2W1 Na(+)/H(+) exchange regulatory cofactor NHE-RF3 chr1 GO:0051223 Not Cancer Driver No 39 0.075 248 14 0.056 0
PFKFB2 PFKFB2 O60825 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 chr1 GO:0051223 Not Cancer Driver No 68 0.135 97 18 0.186 0
PFKL PFKL P17858 ATP-dependent 6-phosphofructokinase, liver type chr21 GO:0051223 Not Cancer Driver No 91 0.117 29 4 0.138 0
PFKM_ENST00000550924 PFKM P08237 ATP-dependent 6-phosphofructokinase, muscle type chr12 GO:0051223 Not Cancer Driver No 80 0.103 70 8 0.114 9
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0051223 Census, Compendium Yes 154 0.213 268 61 0.228 2
PIK3R2_ENST00000617130 PIK3R2 O00459 Phosphatidylinositol 3-kinase regulatory subunit beta chr19 GO:0051223 Not Cancer Driver No 96 0.132 418 47 0.112 3
PIM3 PIM3 Q86V86 Serine/threonine-protein kinase pim-3 chr22 GO:0051223 Not Cancer Driver No 24 0.074 9 0 0.0 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0051223 Not Cancer Driver No 57 0.098 99 13 0.131 23
PKDCC PKDCC Q504Y2 Extracellular tyrosine-protein kinase PKDCC chr2 GO:0051223 Not Cancer Driver No 36 0.073 124 0 0.0 0
PKIA PKIA P61925 cAMP-dependent protein kinase inhibitor alpha chr8 GO:0051223 Not Cancer Driver No 18 0.237 76 18 0.237 0
PKIG_ENST00000372891 PKIG Q9Y2B9 cAMP-dependent protein kinase inhibitor gamma chr20 GO:0051223 Not Cancer Driver No 15 0.197 76 15 0.197 0
PLA2G6 PLA2G6 O60733 85/88 kDa calcium-independent phospholipase A2 chr22 GO:0051223 Not Cancer Driver No 108 0.134 148 23 0.155 11
PLK3 PLK3 Q9H4B4 Serine/threonine-protein kinase PLK3 chr1 GO:0051223 Not Cancer Driver No 75 0.116 202 15 0.074 0
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 GO:0051223 Not Cancer Driver No 72 0.163 69 7 0.101 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0051223 Census Yes 72 0.143 44 4 0.091 3
PPM1A_ENST00000395076 PPM1A P35813 Protein phosphatase 1A chr14 GO:0051223 Not Cancer Driver No 60 0.157 134 24 0.179 0
PPM1F PPM1F P49593 Protein phosphatase 1F chr22 GO:0051223 Not Cancer Driver No 53 0.117 242 24 0.099 0
PPP3CA PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 GO:0051223 Compendium Yes 85 0.163 140 27 0.193 7
PPP3CB_ENST00000360663 PPP3CB P16298 Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform chr10 GO:0051223 Not Cancer Driver No 67 0.128 139 18 0.129 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0051223 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 GO:0051223 Census Yes 53 0.151 24 0 0.0 2
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0051223 Compendium Yes 79 0.117 43 9 0.209 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 GO:0051223 Not Cancer Driver No 107 0.145 170 26 0.153 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0051223 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 GO:0051223 Census Yes 201 0.22 189 33 0.175 2
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0051223 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRNP PRNP P04156 Major prion protein chr20 GO:0051223 Not Cancer Driver No 36 0.142 115 7 0.061 18
PRR5L PRR5L Q6MZQ0 Proline-rich protein 5-like chr11 GO:0051223 Not Cancer Driver No 57 0.155 108 12 0.111 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0051223 Not Cancer Driver No 61 0.131 134 21 0.157 96
PSMD9 PSMD9 O00233 26S proteasome non-ATPase regulatory subunit 9 chr12 GO:0051223 Not Cancer Driver No 22 0.099 173 16 0.092 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0051223 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:0051223 Not Cancer Driver No 49 0.113 140 25 0.179 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0051223 Census, Compendium Yes 129 0.218 260 38 0.146 60
PTPN14 PTPN14 Q15678 Tyrosine-protein phosphatase non-receptor type 14 chr1 GO:0051223 Compendium Yes 173 0.146 582 99 0.17 0
PTPN23 PTPN23 Q9H3S7 Tyrosine-protein phosphatase non-receptor type 23 chr3 GO:0051223 Not Cancer Driver No 147 0.09 796 71 0.089 2
RAB11FIP1 RAB11FIP1 Q6WKZ4 Rab11 family-interacting protein 1 chr8 GO:0051223 Not Cancer Driver No 145 0.113 1118 133 0.119 0
RAB11FIP3 RAB11FIP3 O75154 Rab11 family-interacting protein 3 chr16 GO:0051223 Not Cancer Driver No 51 0.067 605 33 0.055 0
RAB11FIP5 RAB11FIP5 Q9BXF6 Rab11 family-interacting protein 5 chr2 GO:0051223 Not Cancer Driver No 83 0.127 533 70 0.131 0
RAB23_ENST00000317483 RAB23 Q9ULC3 Ras-related protein Rab-23 chr6 GO:0051223 Not Cancer Driver No 28 0.118 62 6 0.097 2
RAB29 RAB29 O14966 Ras-related protein Rab-7L1 chr1 GO:0051223 Not Cancer Driver No 28 0.138 18 3 0.167 0
RAB8A RAB8A P61006 Ras-related protein Rab-8A chr19 GO:0051223 Not Cancer Driver No 37 0.179 26 3 0.115 0
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 GO:0051223 Not Cancer Driver No 31 0.161 0 0 0.0 2
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:0051223 Not Cancer Driver No 34 0.107 13 0 0.0 0
RANGAP1_ENST00000356244 RANGAP1 P46060 Ran GTPase-activating protein 1 chr22 GO:0051223 Not Cancer Driver No 65 0.111 159 17 0.107 0
RAN_ENST00000392369 RAN P62826 GTP-binding nuclear protein Ran chr12 GO:0051223 Not Cancer Driver No 20 0.093 14 1 0.071 0
RAPGEF3 RAPGEF3 O95398 Rap guanine nucleotide exchange factor 3 chr12 GO:0051223 Not Cancer Driver No 97 0.105 197 19 0.096 0
RBM22 RBM22 Q9NW64 Pre-mRNA-splicing factor RBM22 chr5 GO:0051223 Not Cancer Driver No 51 0.121 214 29 0.136 0
RBP4 RBP4 P02753 Retinol-binding protein 4 chr10 GO:0051223 Not Cancer Driver No 30 0.149 8 1 0.125 4
REST REST Q13127 RE1-silencing transcription factor chr4 GO:0051223 Not Cancer Driver No 142 0.129 868 113 0.13 4
RFX6 RFX6 Q8HWS3 DNA-binding protein RFX6 chr6 GO:0051223 Not Cancer Driver No 239 0.258 422 94 0.223 3
RHBDF1 RHBDF1 Q96CC6 Inactive rhomboid protein 1 chr16 GO:0051223 Not Cancer Driver No 96 0.112 316 44 0.139 0
RHBDF2 RHBDF2 Q6PJF5 Inactive rhomboid protein 2 chr17 GO:0051223 Not Cancer Driver No 93 0.109 284 36 0.127 2
RHOU RHOU Q7L0Q8 Rho-related GTP-binding protein RhoU chr1 GO:0051223 Not Cancer Driver No 34 0.132 63 6 0.095 0
RIPOR1_ENST00000379312 RIPOR1 Q6ZS17 Rho family-interacting cell polarization regulator 1 chr16 GO:0051223 Not Cancer Driver No 125 0.102 687 71 0.103 0
RNF31 RNF31 Q96EP0 E3 ubiquitin-protein ligase RNF31 chr14 GO:0051223 Not Cancer Driver No 142 0.132 319 45 0.141 0
RPH3AL RPH3AL Q9UNE2 Rab effector Noc2 chr17 GO:0051223 Not Cancer Driver No 40 0.127 162 20 0.123 0
RSAD2 RSAD2 Q8WXG1 Radical S-adenosyl methionine domain-containing protein 2 chr2 GO:0051223 Not Cancer Driver No 68 0.188 22 1 0.045 0
RSC1A1 RSC1A1 Q92681 Regulatory solute carrier protein family 1 member 1 chr1 GO:0051223 Not Cancer Driver No 63 0.102 548 54 0.099 0
RUFY3_ENST00000226328 RUFY3 Q7L099 Protein RUFY3 chr4 GO:0051223 Not Cancer Driver No 75 0.16 204 29 0.142 0
SAE1 SAE1 Q9UBE0 SUMO-activating enzyme subunit 1 chr19 GO:0051223 Not Cancer Driver No 39 0.113 90 6 0.067 0
SAR1A_ENST00000373238 SAR1A Q9NR31 GTP-binding protein SAR1a chr10 GO:0051223 Not Cancer Driver No 23 0.116 4 0 0.0 0
SAR1B SAR1B Q9Y6B6 GTP-binding protein SAR1b chr5 GO:0051223 Not Cancer Driver No 17 0.086 4 0 0.0 5
SCFD1 SCFD1 Q8WVM8 Sec1 family domain-containing protein 1 chr14 GO:0051223 Not Cancer Driver No 66 0.103 117 12 0.103 0
SEC16B SEC16B Q96JE7 Protein transport protein Sec16B chr1 GO:0051223 Not Cancer Driver No 156 0.147 693 103 0.149 0
SELENOK SELENOK Q9Y6D0 Selenoprotein K chr3 GO:0051223 Not Cancer Driver No 10 0.106 47 6 0.128 0
SERGEF SERGEF Q9UGK8 Secretion-regulating guanine nucleotide exchange factor chr11 GO:0051223 Not Cancer Driver No 49 0.107 91 7 0.077 0
SERP1_ENST00000239944 SERP1 Q9Y6X1 Stress-associated endoplasmic reticulum protein 1 chr3 GO:0051223 Not Cancer Driver No 6 0.091 30 2 0.067 0
SFN SFN P31947 14-3-3 protein sigma chr1 GO:0051223 Not Cancer Driver No 27 0.109 75 9 0.12 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0051223 Not Cancer Driver No 40 0.127 39 7 0.179 0
SH3GLB1_ENST00000370558 SH3GLB1 Q9Y371 Endophilin-B1 chr1 GO:0051223 Not Cancer Driver No 41 0.112 82 10 0.122 0
SH3TC2 SH3TC2 Q8TF17 SH3 domain and tetratricopeptide repeat-containing protein 2 chr5 GO:0051223 Not Cancer Driver No 161 0.125 125 14 0.112 4
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0051223 Not Cancer Driver No 56 0.121 139 14 0.101 81
SIAH3 SIAH3 Q8IW03 Seven in absentia homolog 3 chr13 GO:0051223 Not Cancer Driver No 60 0.223 51 9 0.176 0
SIDT2_ENST00000620360 SIDT2 Q8NBJ9 SID1 transmembrane family member 2 chr11 GO:0051223 Not Cancer Driver No 113 0.136 23 6 0.261 0
SIRT4 SIRT4 Q9Y6E7 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial chr12 GO:0051223 Not Cancer Driver No 46 0.146 4 0 0.0 0
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 GO:0051223 Not Cancer Driver No 48 0.12 163 15 0.092 0
SLC12A2 SLC12A2 P55011 Solute carrier family 12 member 2 chr5 GO:0051223 Not Cancer Driver No 141 0.116 297 18 0.061 8
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0051223 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC30A8 SLC30A8 Q8IWU4 Zinc transporter 8 chr8 GO:0051223 Not Cancer Driver No 115 0.312 25 9 0.36 0
SLC35D3 SLC35D3 Q5M8T2 Solute carrier family 35 member D3 chr6 GO:0051223 Not Cancer Driver No 56 0.135 89 19 0.213 0
SLC51B SLC51B Q86UW2 Organic solute transporter subunit beta chr15 GO:0051223 Not Cancer Driver No 9 0.07 58 5 0.086 0
SLC7A11 SLC7A11 Q9UPY5 Cystine/glutamate transporter chr4 GO:0051223 Not Cancer Driver No 70 0.14 15 2 0.133 0
SLC9B2 SLC9B2 Q86UD5 Sodium/hydrogen exchanger 9B2 chr4 GO:0051223 Not Cancer Driver No 68 0.127 80 16 0.2 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0051223 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMO SMO Q99835 Smoothened homolog chr7 GO:0051223 Census, Compendium Yes 112 0.142 241 27 0.112 1
SNX12 SNX12 Q9UMY4 Sorting nexin-12 chrX GO:0051223 Not Cancer Driver No 22 0.136 28 4 0.143 0
SNX3 SNX3 O60493 Sorting nexin-3 chr6 GO:0051223 Not Cancer Driver No 21 0.13 37 4 0.108 0
SORL1 SORL1 Q92673 Sortilin-related receptor chr11 GO:0051223 Not Cancer Driver No 374 0.169 87 10 0.115 0
SOX4 SOX4 Q06945 Transcription factor SOX-4 chr6 GO:0051223 Not Cancer Driver No 28 0.059 400 24 0.06 4
SP100_ENST00000264052 SP100 P23497 Nuclear autoantigen Sp-100 chr2 GO:0051223 Not Cancer Driver No 136 0.155 680 101 0.149 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0051223 Census Yes 53 0.099 130 11 0.085 1
SREBF1_ENST00000261646 SREBF1 P36956 Sterol regulatory element-binding protein 1 chr17 GO:0051223 Not Cancer Driver No 127 0.111 528 64 0.121 4
SREBF2 SREBF2 Q12772 Sterol regulatory element-binding protein 2 chr22 GO:0051223 Not Cancer Driver No 124 0.109 357 43 0.12 0
SRI SRI P30626 Sorcin chr7 GO:0051223 Not Cancer Driver No 15 0.076 32 2 0.062 0
STOM STOM P27105 Stomatin chr9 GO:0051223 Not Cancer Driver No 23 0.08 44 3 0.068 0
STX4 STX4 Q12846 Syntaxin-4 chr16 GO:0051223 Not Cancer Driver No 50 0.168 152 20 0.132 0
STXBP4 STXBP4 Q6ZWJ1 Syntaxin-binding protein 4 chr17 GO:0051223 Not Cancer Driver No 78 0.141 211 24 0.114 0
SUFU SUFU Q9UMX1 Suppressor of fused homolog chr10 GO:0051223 Census Yes 55 0.114 199 19 0.095 2
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 GO:0051223 Not Cancer Driver No 10 0.099 76 7 0.092 0
SVIP SVIP Q8NHG7 Small VCP/p97-interacting protein chr11 GO:0051223 Not Cancer Driver No 16 0.208 77 16 0.208 0
SYT4 SYT4 Q9H2B2 Synaptotagmin-4 chr18 GO:0051223 Not Cancer Driver No 111 0.261 107 41 0.383 0
SYTL4 SYTL4 Q96C24 Synaptotagmin-like protein 4 chrX GO:0051223 Not Cancer Driver No 116 0.173 267 34 0.127 0
TARDBP TARDBP Q13148 TAR DNA-binding protein 43 chr1 GO:0051223 Not Cancer Driver No 51 0.123 202 15 0.074 27
TCAF1 TCAF1 Q9Y4C2 TRPM8 channel-associated factor 1 chr7 GO:0051223 Not Cancer Driver No 43 0.047 18 3 0.167 0
TCAF2_ENST00000441159 TCAF2 A6NFQ2 TRPM8 channel-associated factor 2 chr7 GO:0051223 Not Cancer Driver No 61 0.066 38 12 0.316 0
TCF7L2_ENST00000355995 TCF7L2 Q9NQB0 Transcription factor 7-like 2 chr10 GO:0051223 Census, Compendium Yes 122 0.197 516 93 0.18 0
TENM1_ENST00000371130 TENM1 Q9UKZ4 Teneurin-1 chrX GO:0051223 Not Cancer Driver No 728 0.267 482 164 0.34 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0051223 Not Cancer Driver No 41 0.105 41 4 0.098 10
TLR2 TLR2 O60603 Toll-like receptor 2 chr4 GO:0051223 Not Cancer Driver No 108 0.138 0 0 0.0 0
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0051223 Not Cancer Driver No 292 0.348 0 0 0.0 0
TM7SF3 TM7SF3 Q9NS93 Transmembrane 7 superfamily member 3 chr12 GO:0051223 Not Cancer Driver No 83 0.146 18 4 0.222 0
TM9SF4 TM9SF4 Q92544 Transmembrane 9 superfamily member 4 chr20 GO:0051223 Not Cancer Driver No 76 0.118 39 4 0.103 0
TMEM30A TMEM30A Q9NV96 Cell cycle control protein 50A chr6 GO:0051223 Not Cancer Driver No 50 0.139 76 8 0.105 0
TMEM30B TMEM30B Q3MIR4 Cell cycle control protein 50B chr14 GO:0051223 Not Cancer Driver No 18 0.051 17 0 0.0 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0051223 Not Cancer Driver No 24 0.103 45 3 0.067 0
TOMM7 TOMM7 Q9P0U1 Mitochondrial import receptor subunit TOM7 homolog chr7 GO:0051223 Not Cancer Driver No 7 0.127 0 0 0.0 0
TOMM70 TOMM70 O94826 Mitochondrial import receptor subunit TOM70 chr3 GO:0051223 Not Cancer Driver No 59 0.097 140 8 0.057 0
TPR TPR P12270 Nucleoprotein TPR chr1 GO:0051223 Census Yes 311 0.132 1990 266 0.134 0
TRH TRH P20396 Pro-thyrotropin-releasing hormone chr3 GO:0051223 Not Cancer Driver No 45 0.186 217 41 0.189 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 GO:0051223 Not Cancer Driver No 87 0.104 430 41 0.095 0
TRPM2_ENST00000397928 TRPM2 O94759 Transient receptor potential cation channel subfamily M member 2 chr21 GO:0051223 Not Cancer Driver No 286 0.19 266 44 0.165 0
TRPM4 TRPM4 Q8TD43 Transient receptor potential cation channel subfamily M member 4 chr19 GO:0051223 Not Cancer Driver No 152 0.125 149 18 0.121 12
TSG101 TSG101 Q99816 Tumor susceptibility gene 101 protein chr11 GO:0051223 Not Cancer Driver No 46 0.118 159 23 0.145 0
TXN TXN P10599 Thioredoxin chr9 GO:0051223 Not Cancer Driver No 6 0.057 0 0 0.0 0
UBAC2 UBAC2 Q8NBM4 Ubiquitin-associated domain-containing protein 2 chr13 GO:0051223 Not Cancer Driver No 33 0.096 57 9 0.158 0
UBE2D3_ENST00000394801 UBE2D3 P61077 Ubiquitin-conjugating enzyme E2 D3 chr4 GO:0051223 Not Cancer Driver No 21 0.143 13 4 0.308 0
UBE2G2 UBE2G2 P60604 Ubiquitin-conjugating enzyme E2 G2 chr21 GO:0051223 Not Cancer Driver No 24 0.145 22 3 0.136 0
UBE2J1 UBE2J1 Q9Y385 Ubiquitin-conjugating enzyme E2 J1 chr6 GO:0051223 Not Cancer Driver No 33 0.104 158 20 0.127 0
UBE2J2_ENST00000349431 UBE2J2 Q8N2K1 Ubiquitin-conjugating enzyme E2 J2 chr1 GO:0051223 Not Cancer Driver No 42 0.162 51 7 0.137 0
UBE2L3_ENST00000342192 UBE2L3 P68036 Ubiquitin-conjugating enzyme E2 L3 chr22 GO:0051223 Not Cancer Driver No 19 0.123 32 4 0.125 0
UBL4B UBL4B Q8N7F7 Ubiquitin-like protein 4B chr1 GO:0051223 Not Cancer Driver No 15 0.086 64 6 0.094 0
UBL5 UBL5 Q9BZL1 Ubiquitin-like protein 5 chr19 GO:0051223 Not Cancer Driver No 5 0.068 0 0 0.0 0
UBR5 UBR5 O95071 E3 ubiquitin-protein ligase UBR5 chr8 GO:0051223 Census, Compendium Yes 340 0.121 1296 162 0.125 0
UCN3 UCN3 Q969E3 Urocortin-3 chr10 GO:0051223 Not Cancer Driver No 22 0.137 74 11 0.149 0
UCP2 UCP2 P55851 Mitochondrial uncoupling protein 2 chr11 GO:0051223 Not Cancer Driver No 31 0.1 11 3 0.273 0
UFM1_ENST00000239878 UFM1 P61960 Ubiquitin-fold modifier 1 chr13 GO:0051223 Not Cancer Driver No 10 0.118 0 0 0.0 1
UHMK1 UHMK1 Q8TAS1 Serine/threonine-protein kinase Kist chr1 GO:0051223 Not Cancer Driver No 42 0.1 14 2 0.143 0
USP17L2 USP17L2 Q6R6M4 Ubiquitin carboxyl-terminal hydrolase 17 chr8 GO:0051223 Not Cancer Driver No 105 0.198 201 54 0.269 0
USP36_ENST00000312010 USP36 Q9P275 Ubiquitin carboxyl-terminal hydrolase 36 chr17 GO:0051223 Not Cancer Driver No 151 0.134 718 91 0.127 0
VAMP2_ENST00000316509 VAMP2 P63027 Vesicle-associated membrane protein 2 chr17 GO:0051223 Not Cancer Driver No 7 0.06 47 4 0.085 3
VPS11 VPS11 Q9H270 Vacuolar protein sorting-associated protein 11 homolog chr11 GO:0051223 Not Cancer Driver No 96 0.102 118 6 0.051 1
VPS28_ENST00000292510 VPS28 Q9UK41 Vacuolar protein sorting-associated protein 28 homolog chr8 GO:0051223 Not Cancer Driver No 28 0.127 31 5 0.161 0
VPS35 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 GO:0051223 Not Cancer Driver No 68 0.085 99 9 0.091 1
VSNL1_ENST00000404666 VSNL1 P62760 Visinin-like protein 1 chr2 GO:0051223 Not Cancer Driver No 28 0.147 15 3 0.2 0
WLS_ENST00000262348 WLS Q5T9L3 Protein wntless homolog chr1 GO:0051223 Not Cancer Driver No 71 0.131 14 3 0.214 0
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 GO:0051223 Not Cancer Driver No 112 0.129 422 57 0.135 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 GO:0051223 Census, Compendium Yes 140 0.131 33 9 0.273 0
XPO4 XPO4 Q9C0E2 Exportin-4 chr13 GO:0051223 Not Cancer Driver No 124 0.108 66 5 0.076 0
YOD1 YOD1 Q5VVQ6 Ubiquitin thioesterase OTU1 chr1 GO:0051223 Not Cancer Driver No 30 0.086 120 6 0.05 0
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 GO:0051223 Census Yes 32 0.125 41 3 0.073 0
ZBED6 ZBED6 P86452 Zinc finger BED domain-containing protein 6 chr1 GO:0051223 Not Cancer Driver No 3 0.003 278 2 0.007 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0051223 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZDHHC2 ZDHHC2 Q9UIJ5 Palmitoyltransferase ZDHHC2 chr8 GO:0051223 Not Cancer Driver No 47 0.128 73 6 0.082 0
ZFAND1 ZFAND1 Q8TCF1 AN1-type zinc finger protein 1 chr8 GO:0051223 Not Cancer Driver No 34 0.127 30 7 0.233 0
ZIC1 ZIC1 Q15915 Zinc finger protein ZIC 1 chr3 GO:0051223 Not Cancer Driver No 187 0.418 246 113 0.459 1
ZPR1 ZPR1 O75312 Zinc finger protein ZPR1 chr11 GO:0051223 Not Cancer Driver No 38 0.083 291 27 0.093 0