Total number of protein in "GO:0051090" GO term: 71
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADCY1 | ADCY1 | Q08828 | Adenylate cyclase type 1 | chr7 | GO:0051090 | Not Cancer Driver | No | 244 | 0.218 | 99 | 19 | 0.192 | 0 |
| ADCY8 | ADCY8 | P40145 | Adenylate cyclase type 8 | chr8 | GO:0051090 | Not Cancer Driver | No | 419 | 0.335 | 215 | 38 | 0.177 | 0 |
| ADGRF1 | ADGRF1 | Q5T601 | Adhesion G-protein coupled receptor F1 | chr6 | GO:0051090 | Not Cancer Driver | No | 159 | 0.175 | 8 | 0 | 0.0 | 0 |
| ADGRG3 | ADGRG3 | Q86Y34 | Adhesion G protein-coupled receptor G3 | chr16 | GO:0051090 | Not Cancer Driver | No | 87 | 0.158 | 42 | 5 | 0.119 | 0 |
| BUD31 | BUD31 | P41223 | Protein BUD31 homolog | chr7 | GO:0051090 | Not Cancer Driver | No | 20 | 0.139 | 32 | 4 | 0.125 | 0 |
| C14orf39 | SIX6OS1 | Q8N1H7 | Protein SIX6OS1 | chr14 | GO:0051090 | Not Cancer Driver | No | 128 | 0.218 | 326 | 76 | 0.233 | 0 |
| C3orf33 | C3orf33 | Q6P1S2 | Protein C3orf33 | chr3 | GO:0051090 | Not Cancer Driver | No | 30 | 0.102 | 23 | 0 | 0.0 | 0 |
| CAMK1D | CAMK1D | Q8IU85 | Calcium/calmodulin-dependent protein kinase type 1D | chr10 | GO:0051090 | Not Cancer Driver | No | 90 | 0.234 | 42 | 14 | 0.333 | 0 |
| CARF | CARF | Q8N187 | Calcium-responsive transcription factor | chr2 | GO:0051090 | Not Cancer Driver | No | 93 | 0.128 | 503 | 63 | 0.125 | 0 |
| CCDC22 | CCDC22 | O60826 | Coiled-coil domain-containing protein 22 | chrX | GO:0051090 | Not Cancer Driver | No | 62 | 0.099 | 243 | 18 | 0.074 | 2 |
| CD200_ENST00000315711 | CD200 | P41217 | OX-2 membrane glycoprotein | chr3 | GO:0051090 | Not Cancer Driver | No | 37 | 0.133 | 14 | 0 | 0.0 | 0 |
| CREBZF | CREBZF | Q9NS37 | CREB/ATF bZIP transcription factor | chr11 | GO:0051090 | Not Cancer Driver | No | 41 | 0.116 | 279 | 34 | 0.122 | 0 |
| CRTC1_ENST00000321949 | CRTC1 | Q6UUV9 | CREB-regulated transcription coactivator 1 | chr19 | GO:0051090 | Census, Compendium | Yes | 63 | 0.099 | 606 | 62 | 0.102 | 0 |
| CRTC2 | CRTC2 | Q53ET0 | CREB-regulated transcription coactivator 2 | chr1 | GO:0051090 | Not Cancer Driver | No | 92 | 0.133 | 674 | 88 | 0.131 | 0 |
| CRTC3 | CRTC3 | Q6UUV7 | CREB-regulated transcription coactivator 3 | chr15 | GO:0051090 | Census | Yes | 70 | 0.113 | 608 | 68 | 0.112 | 0 |
| DDIT3_ENST00000623876 | DDIT3 | P35638 | DNA damage-inducible transcript 3 protein | chr12 | GO:0051090 | Census | Yes | 29 | 0.172 | 160 | 27 | 0.169 | 0 |
| EIF2AK4 | EIF2AK4 | Q9P2K8 | eIF-2-alpha kinase GCN2 | chr15 | GO:0051090 | Not Cancer Driver | No | 156 | 0.095 | 494 | 44 | 0.089 | 2 |
| ENPP1 | ENPP1 | P22413 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 | chr6 | GO:0051090 | Not Cancer Driver | No | 148 | 0.16 | 101 | 5 | 0.05 | 33 |
| EPHA5_ENST00000273854 | EPHA5 | P54756 | Ephrin type-A receptor 5 | chr4 | GO:0051090 | Not Cancer Driver | No | 341 | 0.329 | 83 | 39 | 0.47 | 0 |
| FAF1 | FAF1 | Q9UNN5 | FAS-associated factor 1 | chr1 | GO:0051090 | Not Cancer Driver | No | 83 | 0.128 | 241 | 34 | 0.141 | 0 |
| FANCA | FANCA | O15360 | Fanconi anemia group A protein | chr16 | GO:0051090 | Census, Compendium | Yes | 160 | 0.11 | 154 | 15 | 0.097 | 27 |
| FANCD2_ENST00000383807 | FANCD2 | Q9BXW9 | Fanconi anemia group D2 protein | chr3 | GO:0051090 | Census, Compendium | Yes | 176 | 0.121 | 181 | 14 | 0.077 | 3 |
| FOXP3 | FOXP3 | Q9BZS1 | Forkhead box protein P3 | chrX | GO:0051090 | Not Cancer Driver | No | 38 | 0.088 | 186 | 16 | 0.086 | 10 |
| G3BP2_ENST00000395719 | G3BP2 | Q9UN86 | Ras GTPase-activating protein-binding protein 2 | chr4 | GO:0051090 | Not Cancer Driver | No | 64 | 0.133 | 384 | 53 | 0.138 | 0 |
| GLI1 | GLI1 | P08151 | Zinc finger protein GLI1 | chr12 | GO:0051090 | Census, Compendium | Yes | 206 | 0.186 | 1015 | 184 | 0.181 | 0 |
| GLI3 | GLI3 | P10071 | Transcriptional activator GLI3 | chr7 | GO:0051090 | Not Cancer Driver | No | 385 | 0.244 | 1352 | 327 | 0.242 | 7 |
| HCK_ENST00000534862 | HCK | P08631 | Tyrosine-protein kinase HCK | chr20 | GO:0051090 | Not Cancer Driver | No | 112 | 0.213 | 124 | 25 | 0.202 | 0 |
| HMOX1 | HMOX1 | P09601 | Heme oxygenase 1 | chr22 | GO:0051090 | Not Cancer Driver | No | 46 | 0.16 | 81 | 13 | 0.16 | 0 |
| IL10 | IL10 | P22301 | Interleukin-10 | chr1 | GO:0051090 | Not Cancer Driver | No | 19 | 0.107 | 23 | 1 | 0.043 | 0 |
| KDM5A | KDM5A | P29375 | Lysine-specific demethylase 5A | chr12 | GO:0051090 | Census, Compendium | Yes | 220 | 0.13 | 503 | 66 | 0.131 | 0 |
| KEAP1_ENST00000393623 | KEAP1 | Q14145 | Kelch-like ECH-associated protein 1 | chr19 | GO:0051090 | Census, Compendium | Yes | 237 | 0.38 | 57 | 12 | 0.211 | 0 |
| LPAR5 | LPAR5 | Q9H1C0 | Lysophosphatidic acid receptor 5 | chr12 | GO:0051090 | Not Cancer Driver | No | 40 | 0.108 | 57 | 7 | 0.123 | 0 |
| LRP8 | LRP8 | Q14114 | Low-density lipoprotein receptor-related protein 8 | chr1 | GO:0051090 | Not Cancer Driver | No | 94 | 0.098 | 190 | 24 | 0.126 | 0 |
| MAPK10_ENST00000515650 | MAPK10 | P53779 | Mitogen-activated protein kinase 10 | chr4 | GO:0051090 | Not Cancer Driver | No | 88 | 0.19 | 107 | 16 | 0.15 | 0 |
| MAPK3 | MAPK3 | P27361 | Mitogen-activated protein kinase 3 | chr16 | GO:0051090 | Not Cancer Driver | No | 38 | 0.1 | 49 | 5 | 0.102 | 0 |
| MAPK8_ENST00000374189 | MAPK8 | P45983 | Mitogen-activated protein kinase 8 | chr10 | GO:0051090 | Not Cancer Driver | No | 64 | 0.15 | 94 | 9 | 0.096 | 0 |
| MAPK9 | MAPK9 | P45984 | Mitogen-activated protein kinase 9 | chr5 | GO:0051090 | Not Cancer Driver | No | 59 | 0.139 | 90 | 8 | 0.089 | 0 |
| MDFI | MDFI | Q99750 | MyoD family inhibitor | chr6 | GO:0051090 | Not Cancer Driver | No | 25 | 0.102 | 152 | 15 | 0.099 | 0 |
| MSX2 | MSX2 | P35548 | Homeobox protein MSX-2 | chr5 | GO:0051090 | Not Cancer Driver | No | 27 | 0.101 | 168 | 14 | 0.083 | 4 |
| NFKBIA | NFKBIA | P25963 | NF-kappa-B inhibitor alpha | chr14 | GO:0051090 | Compendium | Yes | 37 | 0.117 | 102 | 9 | 0.088 | 1 |
| NFKBIB | NFKBIB | Q15653 | NF-kappa-B inhibitor beta | chr19 | GO:0051090 | Not Cancer Driver | No | 42 | 0.118 | 223 | 29 | 0.13 | 0 |
| NFKBIE | NFKBIE | O00221 | NF-kappa-B inhibitor epsilon | chr6 | GO:0051090 | Census, Compendium | Yes | 41 | 0.082 | 284 | 16 | 0.056 | 0 |
| OPRD1 | OPRD1 | P41143 | Delta-type opioid receptor | chr1 | GO:0051090 | Not Cancer Driver | No | 91 | 0.245 | 30 | 3 | 0.1 | 0 |
| PARK7_ENST00000377488 | PARK7 | Q99497 | Parkinson disease protein 7 | chr1 | GO:0051090 | Not Cancer Driver | No | 11 | 0.058 | 30 | 0 | 0.0 | 5 |
| PKD1 | PKD1 | P98161 | Polycystin-1 | chr16 | GO:0051090 | Not Cancer Driver | No | 393 | 0.091 | 690 | 66 | 0.096 | 92 |
| PKD2 | PKD2 | Q13563 | Polycystin-2 | chr4 | GO:0051090 | Not Cancer Driver | No | 113 | 0.117 | 375 | 35 | 0.093 | 10 |
| POU4F1 | POU4F1 | Q01851 | POU domain, class 4, transcription factor 1 | chr13 | GO:0051090 | Not Cancer Driver | No | 51 | 0.122 | 273 | 34 | 0.125 | 1 |
| POU4F2 | POU4F2 | Q12837 | POU domain, class 4, transcription factor 2 | chr4 | GO:0051090 | Not Cancer Driver | No | 130 | 0.318 | 308 | 87 | 0.282 | 0 |
| PRKD1_ENST00000616995 | PRKD1 | Q15139 | Serine/threonine-protein kinase D1 | chr14 | GO:0051090 | Census | Yes | 201 | 0.22 | 189 | 33 | 0.175 | 2 |
| PRKD2_ENST00000291281 | PRKD2 | Q9BZL6 | Serine/threonine-protein kinase D2 | chr19 | GO:0051090 | Compendium | Yes | 118 | 0.134 | 246 | 34 | 0.138 | 0 |
| PSMD10 | PSMD10 | O75832 | 26S proteasome non-ATPase regulatory subunit 10 | chrX | GO:0051090 | Not Cancer Driver | No | 20 | 0.088 | 53 | 5 | 0.094 | 0 |
| RELN | RELN | P78509 | Reelin | chr7 | GO:0051090 | Not Cancer Driver | No | 761 | 0.22 | 107 | 19 | 0.178 | 7 |
| RPS6KA4 | RPS6KA4 | O75676 | Ribosomal protein S6 kinase alpha-4 | chr11 | GO:0051090 | Not Cancer Driver | No | 72 | 0.093 | 220 | 11 | 0.05 | 0 |
| RPS6KA5 | RPS6KA5 | O75582 | Ribosomal protein S6 kinase alpha-5 | chr14 | GO:0051090 | Not Cancer Driver | No | 97 | 0.121 | 187 | 18 | 0.096 | 0 |
| RWDD1 | RWDD1 | Q9H446 | RWD domain-containing protein 1 | chr6 | GO:0051090 | Not Cancer Driver | No | 28 | 0.115 | 168 | 19 | 0.113 | 0 |
| SGK1_ENST00000237305 | SGK1 | O00141 | Serine/threonine-protein kinase Sgk1 | chr6 | GO:0051090 | Census, Compendium | Yes | 58 | 0.135 | 86 | 16 | 0.186 | 0 |
| SGK3_ENST00000521198 | SGK3 | Q96BR1 | Serine/threonine-protein kinase Sgk3 | chr8 | GO:0051090 | Not Cancer Driver | No | 54 | 0.109 | 70 | 10 | 0.143 | 0 |
| SHH | SHH | Q15465 | Sonic hedgehog protein | chr7 | GO:0051090 | Not Cancer Driver | No | 56 | 0.121 | 139 | 14 | 0.101 | 81 |
| SIK1 | SIK1 | P57059 | Serine/threonine-protein kinase SIK1 | chr21 | GO:0051090 | Not Cancer Driver | No | 80 | 0.102 | 330 | 30 | 0.091 | 3 |
| SMO | SMO | Q99835 | Smoothened homolog | chr7 | GO:0051090 | Census, Compendium | Yes | 112 | 0.142 | 241 | 27 | 0.112 | 1 |
| SPI1_ENST00000378538 | SPI1 | P17947 | Transcription factor PU.1 | chr11 | GO:0051090 | Not Cancer Driver | No | 46 | 0.17 | 187 | 34 | 0.182 | 0 |
| SRI | SRI | P30626 | Sorcin | chr7 | GO:0051090 | Not Cancer Driver | No | 15 | 0.076 | 32 | 2 | 0.062 | 0 |
| STK36_ENST00000440309 | STK36 | Q9NRP7 | Serine/threonine-protein kinase 36 | chr2 | GO:0051090 | Not Cancer Driver | No | 167 | 0.127 | 250 | 36 | 0.144 | 0 |
| SUFU | SUFU | Q9UMX1 | Suppressor of fused homolog | chr10 | GO:0051090 | Census | Yes | 55 | 0.114 | 199 | 19 | 0.095 | 2 |
| SYK_ENST00000375746 | SYK | P43405 | Tyrosine-protein kinase SYK | chr9 | GO:0051090 | Census | Yes | 96 | 0.151 | 131 | 27 | 0.206 | 5 |
| TAF1_ENST00000373790 | TAF1 | P21675 | Transcription initiation factor TFIID subunit 1 | chrX | GO:0051090 | Not Cancer Driver | No | 379 | 0.202 | 1152 | 219 | 0.19 | 5 |
| TMSB4X_ENST00000380633 | TMSB4X | P62328 | Thymosin beta-4 | chrX | GO:0051090 | Census | Yes | 7 | 0.159 | 44 | 7 | 0.159 | 0 |
| TSSK4_ENST00000287913 | TSSK4 | Q6SA08 | Testis-specific serine/threonine-protein kinase 4 | chr14 | GO:0051090 | Not Cancer Driver | No | 29 | 0.088 | 8 | 1 | 0.125 | 0 |
| USP7 | USP7 | Q93009 | Ubiquitin carboxyl-terminal hydrolase 7 | chr16 | GO:0051090 | Not Cancer Driver | No | 170 | 0.154 | 215 | 45 | 0.209 | 0 |
| VEGFA_ENST00000523873 | VEGFA | P15692 | Vascular endothelial growth factor A | chr6 | GO:0051090 | Not Cancer Driver | No | 27 | 0.116 | 41 | 7 | 0.171 | 0 |
| ZBTB7A_ENST00000601588 | ZBTB7A | O95365 | Zinc finger and BTB domain-containing protein 7A | chr19 | GO:0051090 | Not Cancer Driver | No | 60 | 0.103 | 285 | 30 | 0.105 | 0 |