Total number of protein in "GO:0051087" GO term: 103
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AHSA1 | AHSA1 | O95433 | Activator of 90 kDa heat shock protein ATPase homolog 1 | chr14 | GO:0051087 | Not Cancer Driver | No | 46 | 0.136 | 146 | 17 | 0.116 | 0 |
| ALB | ALB | P02768 | Albumin | chr4 | GO:0051087 | Compendium | Yes | 162 | 0.266 | 6 | 0 | 0.0 | 3 |
| AMFR | AMFR | Q9UKV5 | E3 ubiquitin-protein ligase AMFR | chr16 | GO:0051087 | Not Cancer Driver | No | 73 | 0.114 | 229 | 30 | 0.131 | 0 |
| ATP1A1_ENST00000295598 | ATP1A1 | P05023 | Sodium/potassium-transporting ATPase subunit alpha-1 | chr1 | GO:0051087 | Census | Yes | 115 | 0.112 | 115 | 16 | 0.139 | 6 |
| ATP1A2 | ATP1A2 | P50993 | Sodium/potassium-transporting ATPase subunit alpha-2 | chr1 | GO:0051087 | Not Cancer Driver | No | 230 | 0.225 | 161 | 34 | 0.211 | 8 |
| ATP1A3_ENST00000302102 | ATP1A3 | P13637 | Sodium/potassium-transporting ATPase subunit alpha-3 | chr19 | GO:0051087 | Not Cancer Driver | No | 200 | 0.197 | 115 | 29 | 0.252 | 31 |
| ATP7A | ATP7A | Q04656 | Copper-transporting ATPase 1 | chrX | GO:0051087 | Not Cancer Driver | No | 228 | 0.152 | 171 | 46 | 0.269 | 52 |
| BAG1 | BAG1 | Q99933 | BAG family molecular chaperone regulator 1 | chr9 | GO:0051087 | Not Cancer Driver | No | 29 | 0.084 | 195 | 9 | 0.046 | 0 |
| BAG2 | BAG2 | O95816 | BAG family molecular chaperone regulator 2 | chr6 | GO:0051087 | Not Cancer Driver | No | 17 | 0.081 | 112 | 9 | 0.08 | 0 |
| BAG3 | BAG3 | O95817 | BAG family molecular chaperone regulator 3 | chr10 | GO:0051087 | Not Cancer Driver | No | 57 | 0.099 | 571 | 57 | 0.1 | 7 |
| BAG4 | BAG4 | O95429 | BAG family molecular chaperone regulator 4 | chr8 | GO:0051087 | Not Cancer Driver | No | 55 | 0.12 | 402 | 49 | 0.122 | 0 |
| BAG5_ENST00000299204 | BAG5 | Q9UL15 | BAG family molecular chaperone regulator 5 | chr14 | GO:0051087 | Not Cancer Driver | No | 37 | 0.083 | 63 | 7 | 0.111 | 0 |
| BAK1 | BAK1 | Q16611 | Bcl-2 homologous antagonist/killer | chr6 | GO:0051087 | Not Cancer Driver | No | 38 | 0.18 | 58 | 9 | 0.155 | 0 |
| BAX_ENST00000345358 | BAX | Q07812 | Apoptosis regulator BAX | chr19 | GO:0051087 | Census | Yes | 30 | 0.156 | 39 | 2 | 0.051 | 0 |
| BIN1 | BIN1 | O00499 | Myc box-dependent-interacting protein 1 | chr2 | GO:0051087 | Not Cancer Driver | No | 65 | 0.11 | 456 | 42 | 0.092 | 5 |
| BIRC2 | BIRC2 | Q13490 | Baculoviral IAP repeat-containing protein 2 | chr11 | GO:0051087 | Not Cancer Driver | No | 69 | 0.112 | 83 | 9 | 0.108 | 0 |
| BIRC5_ENST00000350051 | BIRC5 | O15392 | Baculoviral IAP repeat-containing protein 5 | chr17 | GO:0051087 | Not Cancer Driver | No | 20 | 0.141 | 49 | 6 | 0.122 | 0 |
| CALR | CALR | P27797 | Calreticulin | chr19 | GO:0051087 | Census | Yes | 45 | 0.108 | 245 | 31 | 0.127 | 0 |
| CDC25A | CDC25A | P30304 | M-phase inducer phosphatase 1 | chr3 | GO:0051087 | Not Cancer Driver | No | 63 | 0.12 | 313 | 35 | 0.112 | 0 |
| CDC37 | CDC37 | Q16543 | Hsp90 co-chaperone Cdc37 | chr19 | GO:0051087 | Not Cancer Driver | No | 52 | 0.138 | 214 | 31 | 0.145 | 0 |
| CDC37L1 | CDC37L1 | Q7L3B6 | Hsp90 co-chaperone Cdc37-like 1 | chr9 | GO:0051087 | Not Cancer Driver | No | 36 | 0.107 | 122 | 10 | 0.082 | 0 |
| CDKN1B | CDKN1B | P46527 | Cyclin-dependent kinase inhibitor 1B | chr12 | GO:0051087 | Census, Compendium | Yes | 19 | 0.096 | 198 | 19 | 0.096 | 0 |
| CFTR | CFTR | P13569 | Cystic fibrosis transmembrane conductance regulator | chr7 | GO:0051087 | Not Cancer Driver | No | 287 | 0.194 | 145 | 18 | 0.124 | 151 |
| CLU_ENST00000523500 | CLU | P10909 | Clusterin | chr8 | GO:0051087 | Not Cancer Driver | No | 69 | 0.154 | 156 | 27 | 0.173 | 0 |
| CP | CP | P00450 | Ceruloplasmin | chr3 | GO:0051087 | Not Cancer Driver | No | 145 | 0.136 | 197 | 30 | 0.152 | 0 |
| CTSC | CTSC | P53634 | Dipeptidyl peptidase 1 | chr11 | GO:0051087 | Not Cancer Driver | No | 64 | 0.138 | 19 | 5 | 0.263 | 29 |
| DNAJA1 | DNAJA1 | P31689 | DnaJ homolog subfamily A member 1 | chr9 | GO:0051087 | Not Cancer Driver | No | 37 | 0.093 | 153 | 16 | 0.105 | 0 |
| DNAJA2 | DNAJA2 | O60884 | DnaJ homolog subfamily A member 2 | chr16 | GO:0051087 | Not Cancer Driver | No | 50 | 0.121 | 174 | 27 | 0.155 | 0 |
| DNAJA4_ENST00000394852 | DNAJA4 | Q8WW22 | DnaJ homolog subfamily A member 4 | chr15 | GO:0051087 | Not Cancer Driver | No | 43 | 0.108 | 110 | 6 | 0.055 | 0 |
| DNAJB1 | DNAJB1 | P25685 | DnaJ homolog subfamily B member 1 | chr19 | GO:0051087 | Census, Compendium | Yes | 35 | 0.103 | 196 | 26 | 0.133 | 0 |
| DNAJB13 | DNAJB13 | P59910 | DnaJ homolog subfamily B member 13 | chr11 | GO:0051087 | Not Cancer Driver | No | 57 | 0.18 | 42 | 14 | 0.333 | 1 |
| DNAJB2 | DNAJB2 | P25686 | DnaJ homolog subfamily B member 2 | chr2 | GO:0051087 | Not Cancer Driver | No | 51 | 0.157 | 239 | 40 | 0.167 | 1 |
| DNAJB4 | DNAJB4 | Q9UDY4 | DnaJ homolog subfamily B member 4 | chr1 | GO:0051087 | Not Cancer Driver | No | 41 | 0.122 | 160 | 20 | 0.125 | 0 |
| DNAJB5_ENST00000312316 | DNAJB5 | O75953 | DnaJ homolog subfamily B member 5 | chr9 | GO:0051087 | Not Cancer Driver | No | 49 | 0.141 | 147 | 18 | 0.122 | 0 |
| DNAJB6 | DNAJB6 | O75190 | DnaJ homolog subfamily B member 6 | chr7 | GO:0051087 | Not Cancer Driver | No | 33 | 0.101 | 198 | 17 | 0.086 | 3 |
| DNAJB7 | DNAJB7 | Q7Z6W7 | DnaJ homolog subfamily B member 7 | chr22 | GO:0051087 | Not Cancer Driver | No | 43 | 0.139 | 138 | 21 | 0.152 | 0 |
| DNAJB8_ENST00000319153 | DNAJB8 | Q8NHS0 | DnaJ homolog subfamily B member 8 | chr3 | GO:0051087 | Not Cancer Driver | No | 64 | 0.276 | 92 | 30 | 0.326 | 0 |
| DNAJB9 | DNAJB9 | Q9UBS3 | DnaJ homolog subfamily B member 9 | chr7 | GO:0051087 | Not Cancer Driver | No | 30 | 0.135 | 107 | 15 | 0.14 | 0 |
| DNAJC1 | DNAJC1 | Q96KC8 | DnaJ homolog subfamily C member 1 | chr10 | GO:0051087 | Not Cancer Driver | No | 60 | 0.108 | 315 | 44 | 0.14 | 0 |
| DNAJC10 | DNAJC10 | Q8IXB1 | DnaJ homolog subfamily C member 10 | chr2 | GO:0051087 | Not Cancer Driver | No | 110 | 0.139 | 36 | 3 | 0.083 | 0 |
| DNAJC3 | DNAJC3 | Q13217 | DnaJ homolog subfamily C member 3 | chr13 | GO:0051087 | Not Cancer Driver | No | 60 | 0.119 | 131 | 17 | 0.13 | 0 |
| DNAJC9 | DNAJC9 | Q8WXX5 | DnaJ homolog subfamily C member 9 | chr10 | GO:0051087 | Not Cancer Driver | No | 28 | 0.108 | 126 | 15 | 0.119 | 0 |
| DNLZ | DNLZ | Q5SXM8 | DNL-type zinc finger protein | chr9 | GO:0051087 | Not Cancer Driver | No | 15 | 0.084 | 72 | 9 | 0.125 | 0 |
| ERP29 | ERP29 | P30040 | Endoplasmic reticulum resident protein 29 | chr12 | GO:0051087 | Not Cancer Driver | No | 29 | 0.111 | 34 | 5 | 0.147 | 0 |
| FGB | FGB | P02675 | Fibrinogen beta chain | chr4 | GO:0051087 | Not Cancer Driver | No | 89 | 0.181 | 143 | 29 | 0.203 | 7 |
| FICD | FICD | Q9BVA6 | Protein adenylyltransferase FICD | chr12 | GO:0051087 | Not Cancer Driver | No | 46 | 0.1 | 42 | 3 | 0.071 | 0 |
| FN1 | FN1 | P02751 | Fibronectin | chr2 | GO:0051087 | Compendium | Yes | 394 | 0.159 | 1243 | 185 | 0.149 | 8 |
| FNIP1 | FNIP1 | Q8TF40 | Folliculin-interacting protein 1 | chr5 | GO:0051087 | Not Cancer Driver | No | 143 | 0.123 | 384 | 44 | 0.115 | 0 |
| FNIP2 | FNIP2 | Q9P278 | Folliculin-interacting protein 2 | chr4 | GO:0051087 | Not Cancer Driver | No | 119 | 0.107 | 555 | 71 | 0.128 | 0 |
| GAK | GAK | O14976 | Cyclin-G-associated kinase | chr4 | GO:0051087 | Not Cancer Driver | No | 146 | 0.111 | 589 | 79 | 0.134 | 0 |
| GET4 | GET4 | Q7L5D6 | Golgi to ER traffic protein 4 homolog | chr7 | GO:0051087 | Not Cancer Driver | No | 34 | 0.104 | 51 | 3 | 0.059 | 0 |
| GNB5 | GNB5 | O14775 | Guanine nucleotide-binding protein subunit beta-5 | chr15 | GO:0051087 | Not Cancer Driver | No | 60 | 0.152 | 16 | 1 | 0.062 | 1 |
| GRN | GRN | P28799 | Progranulin | chr17 | GO:0051087 | Not Cancer Driver | No | 76 | 0.128 | 29 | 6 | 0.207 | 1 |
| GRPEL1 | GRPEL1 | Q9HAV7 | GrpE protein homolog 1, mitochondrial | chr4 | GO:0051087 | Not Cancer Driver | No | 22 | 0.101 | 88 | 7 | 0.08 | 0 |
| GRPEL2 | GRPEL2 | Q8TAA5 | GrpE protein homolog 2, mitochondrial | chr5 | GO:0051087 | Not Cancer Driver | No | 17 | 0.076 | 45 | 3 | 0.067 | 0 |
| HES1 | HES1 | Q14469 | Transcription factor HES-1 | chr3 | GO:0051087 | Not Cancer Driver | No | 37 | 0.132 | 226 | 32 | 0.142 | 0 |
| HLA-B | HLA-B | P01889 | HLA class I histocompatibility antigen, B alpha chain | chr6 | GO:0051087 | Compendium | Yes | 78 | 0.215 | 169 | 34 | 0.201 | 0 |
| HSCB | HSCB | Q8IWL3 | Iron-sulfur cluster co-chaperone protein HscB | chr22 | GO:0051087 | Not Cancer Driver | No | 36 | 0.153 | 25 | 6 | 0.24 | 0 |
| HSPA2_ENST00000247207 | HSPA2 | P54652 | Heat shock-related 70 kDa protein 2 | chr14 | GO:0051087 | Not Cancer Driver | No | 93 | 0.146 | 286 | 38 | 0.133 | 0 |
| HSPA5 | HSPA5 | P11021 | Endoplasmic reticulum chaperone BiP | chr9 | GO:0051087 | Not Cancer Driver | No | 73 | 0.112 | 282 | 35 | 0.124 | 0 |
| HSPA8_ENST00000532636 | HSPA8 | P11142 | Heat shock cognate 71 kDa protein | chr11 | GO:0051087 | Not Cancer Driver | No | 149 | 0.231 | 251 | 52 | 0.207 | 0 |
| HSPB6 | HSPB6 | O14558 | Heat shock protein beta-6 | chr19 | GO:0051087 | Not Cancer Driver | No | 5 | 0.031 | 56 | 0 | 0.0 | 0 |
| HSPD1 | HSPD1 | P10809 | 60 kDa heat shock protein, mitochondrial | chr2 | GO:0051087 | Not Cancer Driver | No | 61 | 0.106 | 82 | 6 | 0.073 | 2 |
| HSPE1 | HSPE1 | P61604 | 10 kDa heat shock protein, mitochondrial | chr2 | GO:0051087 | Not Cancer Driver | No | 8 | 0.078 | 3 | 0 | 0.0 | 0 |
| HYOU1 | HYOU1 | Q9Y4L1 | Hypoxia up-regulated protein 1 | chr11 | GO:0051087 | Not Cancer Driver | No | 132 | 0.132 | 373 | 47 | 0.126 | 0 |
| LRP2 | LRP2 | P98164 | Low-density lipoprotein receptor-related protein 2 | chr2 | GO:0051087 | Not Cancer Driver | No | 998 | 0.214 | 209 | 40 | 0.191 | 1 |
| MAPT_ENST00000262410 | MAPT | P10636 | Microtubule-associated protein tau | chr17 | GO:0051087 | Not Cancer Driver | No | 128 | 0.169 | 750 | 126 | 0.168 | 18 |
| OGDH | OGDH | Q02218 | 2-oxoglutarate dehydrogenase complex component E1 | chr7 | GO:0051087 | Not Cancer Driver | No | 150 | 0.147 | 106 | 19 | 0.179 | 0 |
| PACRG | PACRG | Q96M98 | Parkin coregulated gene protein | chr6 | GO:0051087 | Not Cancer Driver | No | 66 | 0.223 | 45 | 6 | 0.133 | 0 |
| PDPN_ENST00000621990 | PDPN | Q86YL7 | Podoplanin | chr1 | GO:0051087 | Not Cancer Driver | No | 37 | 0.228 | 96 | 24 | 0.25 | 0 |
| PFDN4 | PFDN4 | Q9NQP4 | Prefoldin subunit 4 | chr20 | GO:0051087 | Not Cancer Driver | No | 22 | 0.164 | 40 | 6 | 0.15 | 0 |
| PFDN6_ENST00000374610 | PFDN6 | O15212 | Prefoldin subunit 6 | chr6 | GO:0051087 | Not Cancer Driver | No | 14 | 0.109 | 57 | 8 | 0.14 | 0 |
| PIH1D3_ENST00000372453 | DNAAF6 | Q9NQM4 | Dynein axonemal assembly factor 6 | chrX | GO:0051087 | Not Cancer Driver | No | 23 | 0.107 | 114 | 12 | 0.105 | 1 |
| PLG | PLG | P00747 | Plasminogen | chr6 | GO:0051087 | Not Cancer Driver | No | 242 | 0.299 | 230 | 64 | 0.278 | 9 |
| PRKN | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | GO:0051087 | Not Cancer Driver | No | 110 | 0.237 | 78 | 15 | 0.192 | 31 |
| PRNP | PRNP | P04156 | Major prion protein | chr20 | GO:0051087 | Not Cancer Driver | No | 36 | 0.142 | 115 | 7 | 0.061 | 18 |
| PTGES3_ENST00000262033 | PTGES3 | Q15185 | Prostaglandin E synthase 3 | chr12 | GO:0051087 | Not Cancer Driver | No | 11 | 0.069 | 52 | 3 | 0.058 | 0 |
| RNF207 | RNF207 | Q6ZRF8 | RING finger protein 207 | chr1 | GO:0051087 | Not Cancer Driver | No | 48 | 0.076 | 198 | 13 | 0.066 | 0 |
| SACS | SACS | Q9NZJ4 | Sacsin | chr13 | GO:0051087 | Not Cancer Driver | No | 683 | 0.149 | 272 | 41 | 0.151 | 24 |
| SCARB2 | SCARB2 | Q14108 | Lysosome membrane protein 2 | chr4 | GO:0051087 | Not Cancer Driver | No | 61 | 0.128 | 13 | 3 | 0.231 | 1 |
| SDF2L1 | SDF2L1 | Q9HCN8 | Stromal cell-derived factor 2-like protein 1 | chr22 | GO:0051087 | Not Cancer Driver | No | 16 | 0.072 | 130 | 9 | 0.069 | 0 |
| SLC12A2 | SLC12A2 | P55011 | Solute carrier family 12 member 2 | chr5 | GO:0051087 | Not Cancer Driver | No | 141 | 0.116 | 297 | 18 | 0.061 | 8 |
| SLC25A17 | SLC25A17 | O43808 | Peroxisomal membrane protein PMP34 | chr22 | GO:0051087 | Not Cancer Driver | No | 32 | 0.104 | 0 | 0 | 0.0 | 0 |
| SOD1 | SOD1 | P00441 | Superoxide dismutase [Cu-Zn] | chr21 | GO:0051087 | Not Cancer Driver | No | 16 | 0.104 | 93 | 9 | 0.097 | 79 |
| STUB1 | STUB1 | Q9UNE7 | E3 ubiquitin-protein ligase CHIP | chr16 | GO:0051087 | Not Cancer Driver | No | 35 | 0.116 | 112 | 14 | 0.125 | 12 |
| SUGT1 | SUGT1 | Q9Y2Z0 | Protein SGT1 homolog | chr13 | GO:0051087 | Not Cancer Driver | No | 31 | 0.085 | 119 | 5 | 0.042 | 0 |
| SYVN1 | SYVN1 | Q86TM6 | E3 ubiquitin-protein ligase synoviolin | chr11 | GO:0051087 | Not Cancer Driver | No | 63 | 0.102 | 284 | 32 | 0.113 | 0 |
| TBCA_ENST00000380377 | TBCA | O75347 | Tubulin-specific chaperone A | chr5 | GO:0051087 | Not Cancer Driver | No | 8 | 0.074 | 30 | 1 | 0.033 | 0 |
| TBCC | TBCC | Q15814 | Tubulin-specific chaperone C | chr6 | GO:0051087 | Not Cancer Driver | No | 29 | 0.084 | 107 | 12 | 0.112 | 0 |
| TBCD | TBCD | Q9BTW9 | Tubulin-specific chaperone D | chr17 | GO:0051087 | Not Cancer Driver | No | 156 | 0.131 | 60 | 9 | 0.15 | 11 |
| TBCE_ENST00000645351 | TBCE | Q15813 | Tubulin-specific chaperone E | chr1 | GO:0051087 | Not Cancer Driver | No | 70 | 0.133 | 87 | 7 | 0.08 | 1 |
| TERT | TERT | O14746 | Telomerase reverse transcriptase | chr5 | GO:0051087 | Census | Yes | 110 | 0.097 | 212 | 16 | 0.075 | 31 |
| TFRC_ENST00000392396 | TFRC | P02786 | Transferrin receptor protein 1 | chr3 | GO:0051087 | Census | Yes | 89 | 0.117 | 80 | 6 | 0.075 | 1 |
| TIMM10_ENST00000525587 | TIMM10 | P62072 | Mitochondrial import inner membrane translocase subunit Tim10 | chr11 | GO:0051087 | Not Cancer Driver | No | 6 | 0.067 | 43 | 6 | 0.14 | 0 |
| TIMM44 | TIMM44 | O43615 | Mitochondrial import inner membrane translocase subunit TIM44 | chr19 | GO:0051087 | Not Cancer Driver | No | 56 | 0.124 | 175 | 22 | 0.126 | 0 |
| TIMM9_ENST00000555593 | TIMM9 | Q9Y5J7 | Mitochondrial import inner membrane translocase subunit Tim9 | chr14 | GO:0051087 | Not Cancer Driver | No | 9 | 0.101 | 8 | 1 | 0.125 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0051087 | Census, Compendium | Yes | 2891 | 7.356 | 282 | 1466 | 5.199 | 83 |
| TSACC_ENST00000368254 | TSACC | Q96A04 | TSSK6-activating co-chaperone protein | chr1 | GO:0051087 | Not Cancer Driver | No | 18 | 0.144 | 102 | 13 | 0.127 | 0 |
| TSC1 | TSC1 | Q92574 | Hamartin | chr9 | GO:0051087 | Census, Compendium | Yes | 135 | 0.116 | 732 | 78 | 0.107 | 11 |
| UBL4A | UBL4A | P11441 | Ubiquitin-like protein 4A | chrX | GO:0051087 | Not Cancer Driver | No | 22 | 0.14 | 16 | 5 | 0.312 | 0 |
| USP13 | USP13 | Q92995 | Ubiquitin carboxyl-terminal hydrolase 13 | chr3 | GO:0051087 | Not Cancer Driver | No | 121 | 0.14 | 224 | 42 | 0.188 | 0 |
| VWF | VWF | P04275 | von Willebrand factor | chr12 | GO:0051087 | Not Cancer Driver | No | 456 | 0.162 | 91 | 16 | 0.176 | 43 |
| WRAP53 | WRAP53 | Q9BUR4 | Telomerase Cajal body protein 1 | chr17 | GO:0051087 | Not Cancer Driver | No | 66 | 0.12 | 232 | 29 | 0.125 | 4 |