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Total number of protein in "GO:0050863" GO term:  237

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0050863 Census, Compendium Yes 139 0.123 604 73 0.121 2
ADA ADA P00813 Adenosine deaminase chr20 GO:0050863 Not Cancer Driver No 50 0.138 44 9 0.205 27
ADAM8 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:0050863 Not Cancer Driver No 82 0.1 230 13 0.057 0
ADORA2A ADORA2A P29274 Adenosine receptor A2a chr22 GO:0050863 Not Cancer Driver No 61 0.148 93 11 0.118 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0050863 Not Cancer Driver No 31 0.077 297 21 0.071 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0050863 Census, Compendium Yes 108 0.225 158 24 0.152 4
AMBRA1_ENST00000458649 AMBRA1 Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 chr11 GO:0050863 Not Cancer Driver No 173 0.133 788 103 0.131 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0050863 Not Cancer Driver No 59 0.171 61 12 0.197 0
AP3B1 AP3B1 O00203 AP-3 complex subunit beta-1 chr5 GO:0050863 Not Cancer Driver No 126 0.115 316 31 0.098 1
AP3D1_ENST00000345016 AP3D1 O14617 AP-3 complex subunit delta-1 chr19 GO:0050863 Not Cancer Driver No 138 0.12 404 59 0.146 0
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:0050863 Not Cancer Driver No 41 0.127 83 12 0.145 9
ARG2 ARG2 P78540 Arginase-2, mitochondrial chr14 GO:0050863 Not Cancer Driver No 25 0.071 58 3 0.052 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0050863 Census, Compendium Yes 134 0.19 328 67 0.204 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0050863 Not Cancer Driver No 86 0.211 142 26 0.183 5
BTN2A2 BTN2A2 Q8WVV5 Butyrophilin subfamily 2 member A2 chr6 GO:0050863 Not Cancer Driver No 92 0.176 24 2 0.083 0
CAMK4_ENST00000512453 CAMK4 Q16566 Calcium/calmodulin-dependent protein kinase type IV chr5 GO:0050863 Not Cancer Driver No 101 0.214 127 30 0.236 0
CARD11 CARD11 Q9BXL7 Caspase recruitment domain-containing protein 11 chr7 GO:0050863 Census, Compendium Yes 303 0.263 530 140 0.264 5
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0050863 Census Yes 32 0.116 62 5 0.081 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0050863 Not Cancer Driver No 30 0.169 2 0 0.0 0
CBFB_ENST00000290858 CBFB Q13951 Core-binding factor subunit beta chr16 GO:0050863 Census, Compendium Yes 39 0.214 94 17 0.181 0
CBLB CBLB Q13191 E3 ubiquitin-protein ligase CBL-B chr3 GO:0050863 Census Yes 160 0.163 562 104 0.185 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0050863 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0050863 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCR2_ENST00000400888 CCR2 P41597 C-C chemokine receptor type 2 chr3 GO:0050863 Not Cancer Driver No 81 0.217 23 1 0.043 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0050863 Census, Compendium Yes 50 0.132 0 0 0.0 0
CD160_ENST00000369288 CD160 O95971 CD160 antigen chr1 GO:0050863 Not Cancer Driver No 20 0.11 2 0 0.0 0
CD2 CD2 P06729 T-cell surface antigen CD2 chr1 GO:0050863 Not Cancer Driver No 75 0.214 126 35 0.278 0
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 GO:0050863 Census Yes 29 0.1 54 9 0.167 0
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:0050863 Census Yes 42 0.191 18 10 0.556 0
CD300A CD300A Q9UGN4 CMRF35-like molecule 8 chr17 GO:0050863 Not Cancer Driver No 53 0.177 70 10 0.143 0
CD3E CD3E P07766 T-cell surface glycoprotein CD3 epsilon chain chr11 GO:0050863 Not Cancer Driver No 28 0.135 72 12 0.167 0
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 GO:0050863 Not Cancer Driver No 69 0.151 56 11 0.196 0
CD40LG CD40LG P29965 CD40 ligand chrX GO:0050863 Not Cancer Driver No 56 0.215 24 7 0.292 32
CD46_ENST00000358170 CD46 P15529 Membrane cofactor protein chr1 GO:0050863 Not Cancer Driver No 53 0.135 52 4 0.077 5
CD5 CD5 P06127 T-cell surface glycoprotein CD5 chr11 GO:0050863 Not Cancer Driver No 67 0.135 146 19 0.13 0
CD55_ENST00000367064 CD55 P08174 Complement decay-accelerating factor chr1 GO:0050863 Not Cancer Driver No 45 0.118 128 13 0.102 1
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0050863 Census Yes 31 0.105 185 20 0.108 0
CD80_ENST00000478182 CD80 P33681 T-lymphocyte activation antigen CD80 chr3 GO:0050863 Not Cancer Driver No 50 0.174 26 5 0.192 0
CD81 CD81 P60033 CD81 antigen chr11 GO:0050863 Not Cancer Driver No 28 0.119 0 0 0.0 0
CD83 CD83 Q01151 CD83 antigen chr6 GO:0050863 Not Cancer Driver No 24 0.117 48 8 0.167 0
CD86 CD86 P42081 T-lymphocyte activation antigen CD86 chr3 GO:0050863 Not Cancer Driver No 90 0.274 56 18 0.321 0
CEACAM1 CEACAM1 P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 chr19 GO:0050863 Not Cancer Driver No 64 0.122 241 25 0.104 0
CGAS CGAS Q8N884 Cyclic GMP-AMP synthase chr6 GO:0050863 Not Cancer Driver No 50 0.096 173 7 0.04 0
CLC CLC Q05315 Galectin-10 chr19 GO:0050863 Not Cancer Driver No 29 0.204 0 0 0.0 0
CLPTM1 CLPTM1 O96005 Cleft lip and palate transmembrane protein 1 chr19 GO:0050863 Not Cancer Driver No 83 0.124 163 19 0.117 0
CR1_ENST00000367053 CR1 P17927 Complement receptor type 1 chr1 GO:0050863 Compendium Yes 383 0.188 151 42 0.278 0
CRTAM CRTAM O95727 Cytotoxic and regulatory T-cell molecule chr11 GO:0050863 Not Cancer Driver No 64 0.163 135 14 0.104 0
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 GO:0050863 Not Cancer Driver No 41 0.091 18 1 0.056 0
CTLA4 CTLA4 P16410 Cytotoxic T-lymphocyte protein 4 chr2 GO:0050863 Not Cancer Driver No 37 0.166 3 0 0.0 1
CYP26B1 CYP26B1 Q9NR63 Cytochrome P450 26B1 chr2 GO:0050863 Not Cancer Driver No 113 0.221 10 3 0.3 2
DOCK8 DOCK8 Q8NF50 Dedicator of cytokinesis protein 8 chr9 GO:0050863 Not Cancer Driver No 321 0.153 312 60 0.192 1
DPP4 DPP4 P27487 Dipeptidyl peptidase 4 chr2 GO:0050863 Not Cancer Driver No 151 0.197 8 1 0.125 0
DROSHA_ENST00000344624 DROSHA Q9NRR4 Ribonuclease 3 chr5 GO:0050863 Census, Compendium Yes 175 0.127 682 100 0.147 0
DUSP10 DUSP10 Q9Y6W6 Dual specificity protein phosphatase 10 chr1 GO:0050863 Not Cancer Driver No 81 0.168 135 24 0.178 0
EBI3 EBI3 Q14213 Interleukin-27 subunit beta chr19 GO:0050863 Not Cancer Driver No 32 0.14 10 1 0.1 0
EFNB1 EFNB1 P98172 Ephrin-B1 chrX GO:0050863 Not Cancer Driver No 46 0.133 126 14 0.111 19
EFNB2_ENST00000245323 EFNB2 P52799 Ephrin-B2 chr13 GO:0050863 Not Cancer Driver No 42 0.126 97 15 0.155 0
EFNB3 EFNB3 Q15768 Ephrin-B3 chr17 GO:0050863 Not Cancer Driver No 45 0.132 183 22 0.12 0
EGR3 EGR3 Q06889 Early growth response protein 3 chr8 GO:0050863 Not Cancer Driver No 60 0.155 252 46 0.183 0
EPO EPO P01588 Erythropoietin chr7 GO:0050863 Not Cancer Driver No 27 0.14 9 1 0.111 1
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0050863 Census, Compendium Yes 275 0.219 314 41 0.131 1
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0050863 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAM49B_ENST00000519540 CYRIB Q9NUQ9 CYFIP-related Rac1 interactor B chr8 GO:0050863 Not Cancer Driver No 53 0.164 78 11 0.141 0
FANCA FANCA O15360 Fanconi anemia group A protein chr16 GO:0050863 Census, Compendium Yes 160 0.11 154 15 0.097 27
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 GO:0050863 Census, Compendium Yes 176 0.121 181 14 0.077 3
FCGR2B FCGR2B P31994 Low affinity immunoglobulin gamma Fc region receptor II-b chr1 GO:0050863 Census Yes 51 0.165 99 30 0.303 0
FGL2 FGL2 Q14314 Fibroleukin chr7 GO:0050863 Not Cancer Driver No 71 0.162 70 12 0.171 0
FLOT2 FLOT2 Q14254 Flotillin-2 chr17 GO:0050863 Not Cancer Driver No 56 0.131 20 3 0.15 0
FOXJ1 FOXJ1 Q92949 Forkhead box protein J1 chr17 GO:0050863 Not Cancer Driver No 25 0.059 279 18 0.065 0
FOXN1 FOXN1 O15353 Forkhead box protein N1 chr17 GO:0050863 Not Cancer Driver No 90 0.139 483 65 0.135 2
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0050863 Census, Compendium Yes 70 0.104 595 68 0.114 0
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0050863 Not Cancer Driver No 38 0.088 186 16 0.086 10
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0050863 Not Cancer Driver No 92 0.171 70 13 0.186 0
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0050863 Census, Compendium Yes 111 0.251 364 87 0.239 2
GLI2_ENST00000361492 GLI2 P10070 Zinc finger protein GLI2 chr2 GO:0050863 Not Cancer Driver No 287 0.181 1403 244 0.174 2
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0050863 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GPAM GPAM Q9HCL2 Glycerol-3-phosphate acyltransferase 1, mitochondrial chr10 GO:0050863 Not Cancer Driver No 108 0.13 83 7 0.084 0
HAVCR2 HAVCR2 Q8TDQ0 Hepatitis A virus cellular receptor 2 chr5 GO:0050863 Not Cancer Driver No 69 0.229 17 2 0.118 3
HFE HFE Q30201 Hereditary hemochromatosis protein chr6 GO:0050863 Not Cancer Driver No 55 0.158 27 2 0.074 11
HHLA2_ENST00000489514 HHLA2 Q9UM44 HERV-H LTR-associating protein 2 chr3 GO:0050863 Not Cancer Driver No 85 0.205 57 10 0.175 0
HLA-A_ENST00000376809 HLA-A P04439 HLA class I histocompatibility antigen, A alpha chain chr6 GO:0050863 Census, Compendium Yes 128 0.351 125 60 0.48 0
HLA-DMB HLA-DMB P28068 HLA class II histocompatibility antigen, DM beta chain chr6 GO:0050863 Not Cancer Driver No 41 0.156 41 9 0.22 0
HLA-DOA HLA-DOA P06340 HLA class II histocompatibility antigen, DO alpha chain chr6 GO:0050863 Not Cancer Driver No 39 0.156 7 1 0.143 0
HLA-DRA HLA-DRA P01903 HLA class II histocompatibility antigen, DR alpha chain chr6 GO:0050863 Not Cancer Driver No 52 0.205 12 1 0.083 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0050863 Not Cancer Driver No 48 0.18 12 1 0.083 0
HLA-E HLA-E P13747 HLA class I histocompatibility antigen, alpha chain E chr6 GO:0050863 Not Cancer Driver No 63 0.176 138 39 0.283 0
HLA-G_ENST00000360323 HLA-G P17693 HLA class I histocompatibility antigen, alpha chain G chr6 GO:0050863 Not Cancer Driver No 94 0.278 85 22 0.259 0
HLX HLX Q14774 H2.0-like homeobox protein chr1 GO:0050863 Not Cancer Driver No 107 0.219 412 98 0.238 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0050863 Not Cancer Driver No 25 0.116 203 20 0.099 0
HSPH1_ENST00000320027 HSPH1 Q92598 Heat shock protein 105 kDa chr13 GO:0050863 Not Cancer Driver No 103 0.12 323 42 0.13 0
ICOS ICOS Q9Y6W8 Inducible T-cell costimulator chr2 GO:0050863 Not Cancer Driver No 36 0.181 0 0 0.0 0
ICOSLG_ENST00000407780 ICOSLG O75144 ICOS ligand chr21 GO:0050863 Not Cancer Driver No 25 0.083 30 2 0.067 0
IDO1_ENST00000522495 IDO1 P14902 Indoleamine 2,3-dioxygenase 1 chr8 GO:0050863 Not Cancer Driver No 82 0.203 41 8 0.195 0
IFNA2 IFNA2 P01563 Interferon alpha-2 chr9 GO:0050863 Not Cancer Driver No 38 0.202 2 0 0.0 0
IFNB1 IFNB1 P01574 Interferon beta chr9 GO:0050863 Not Cancer Driver No 46 0.246 0 0 0.0 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0050863 Not Cancer Driver No 51 0.307 23 6 0.261 0
IFNL1 IFNL1 Q8IU54 Interferon lambda-1 chr19 GO:0050863 Not Cancer Driver No 24 0.12 49 8 0.163 0
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0050863 Not Cancer Driver No 45 0.231 87 23 0.264 0
IGF2_ENST00000641326 IGF2 P01344 Insulin-like growth factor II chr11 GO:0050863 Not Cancer Driver No 39 0.217 44 12 0.273 0
IGFBP2 IGFBP2 P18065 Insulin-like growth factor-binding protein 2 chr2 GO:0050863 Not Cancer Driver No 32 0.098 171 24 0.14 0
IHH IHH Q14623 Indian hedgehog protein chr2 GO:0050863 Not Cancer Driver No 58 0.141 111 15 0.135 6
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0050863 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL12RB1_ENST00000593993 IL12RB1 P42701 Interleukin-12 receptor subunit beta-1 chr19 GO:0050863 Not Cancer Driver No 108 0.163 207 38 0.184 1
IL15_ENST00000320650 IL15 P40933 Interleukin-15 chr4 GO:0050863 Not Cancer Driver No 25 0.154 6 1 0.167 0
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0050863 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0050863 Not Cancer Driver No 30 0.111 35 6 0.171 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0050863 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL2 IL2 P60568 Interleukin-2 chr4 GO:0050863 Census Yes 24 0.157 6 1 0.167 0
IL23A IL23A Q9NPF7 Interleukin-23 subunit alpha chr12 GO:0050863 Not Cancer Driver No 15 0.079 42 3 0.071 0
IL23R IL23R Q5VWK5 Interleukin-23 receptor chr1 GO:0050863 Not Cancer Driver No 70 0.111 117 19 0.162 0
IL27 IL27 Q8NEV9 Interleukin-27 subunit alpha chr16 GO:0050863 Not Cancer Driver No 37 0.152 27 1 0.037 0
IL27RA IL27RA Q6UWB1 Interleukin-27 receptor subunit alpha chr19 GO:0050863 Not Cancer Driver No 91 0.143 167 23 0.138 0
IL2RA IL2RA P01589 Interleukin-2 receptor subunit alpha chr10 GO:0050863 Not Cancer Driver No 51 0.188 131 29 0.221 2
IL4 IL4 P05112 Interleukin-4 chr5 GO:0050863 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL4I1_ENST00000391826 IL4I1 Q96RQ9 L-amino-acid oxidase chr19 GO:0050863 Not Cancer Driver No 65 0.115 136 14 0.103 0
IL4R_ENST00000543915 IL4R P24394 Interleukin-4 receptor subunit alpha chr16 GO:0050863 Not Cancer Driver No 133 0.161 420 64 0.152 0
IL7R IL7R P16871 Interleukin-7 receptor subunit alpha chr5 GO:0050863 Census, Compendium Yes 177 0.386 88 48 0.545 1
IRF1 IRF1 P10914 Interferon regulatory factor 1 chr5 GO:0050863 Compendium Yes 49 0.151 228 31 0.136 2
IRF4 IRF4 Q15306 Interferon regulatory factor 4 chr6 GO:0050863 Census, Compendium Yes 99 0.22 155 45 0.29 0
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 GO:0050863 Not Cancer Driver No 95 0.105 335 42 0.125 0
ITPKB_ENST00000272117 ITPKB P27987 Inositol-trisphosphate 3-kinase B chr1 GO:0050863 Not Cancer Driver No 148 0.156 719 119 0.166 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0050863 Census, Compendium Yes 136 0.12 59 5 0.085 5
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 GO:0050863 Census, Compendium Yes 167 0.149 63 10 0.159 7
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 GO:0050863 Not Cancer Driver No 88 0.105 251 17 0.068 0
KLRK1 KLRK1 P26718 NKG2-D type II integral membrane protein chr12 GO:0050863 Not Cancer Driver No 38 0.176 0 0 0.0 0
LAG3 LAG3 P18627 Lymphocyte activation gene 3 protein chr12 GO:0050863 Not Cancer Driver No 47 0.09 208 11 0.053 0
LAT_ENST00000360872 LAT O43561 Linker for activation of T-cells family member 1 chr16 GO:0050863 Not Cancer Driver No 37 0.141 213 29 0.136 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 GO:0050863 Census Yes 86 0.169 94 13 0.138 1
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:0050863 Census Yes 64 0.16 370 57 0.154 0
LGALS1 LGALS1 P09382 Galectin-1 chr22 GO:0050863 Not Cancer Driver No 16 0.119 0 0 0.0 0
LGALS3 LGALS3 P17931 Galectin-3 chr14 GO:0050863 Not Cancer Driver No 15 0.06 133 6 0.045 0
LGALS7B LGALS7B P47929 Galectin-7 chr19 GO:0050863 Not Cancer Driver No 14 0.103 54 5 0.093 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0050863 Not Cancer Driver No 54 0.152 65 16 0.246 0
LGALS9B_ENST00000423676 LGALS9B Q3B8N2 Galectin-9B chr17 GO:0050863 Not Cancer Driver No 43 0.121 86 19 0.221 0
LGALS9C LGALS9C Q6DKI2 Galectin-9C chr17 GO:0050863 Not Cancer Driver No 32 0.09 80 6 0.075 0
LILRB1_ENST00000396331 LILRB1 Q8NHL6 Leukocyte immunoglobulin-like receptor subfamily B member 1 chr19 GO:0050863 Not Cancer Driver No 203 0.312 291 97 0.333 0
LILRB2_ENST00000314446 LILRB2 Q8N423 Leukocyte immunoglobulin-like receptor subfamily B member 2 chr19 GO:0050863 Not Cancer Driver No 148 0.248 235 50 0.213 0
LILRB4 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 GO:0050863 Not Cancer Driver No 162 0.362 277 115 0.415 0
LMO1 LMO1 P25800 Rhombotin-1 chr11 GO:0050863 Census Yes 23 0.147 0 0 0.0 0
LOXL3 LOXL3 P58215 Lysyl oxidase homolog 3 chr2 GO:0050863 Not Cancer Driver No 91 0.121 86 17 0.198 0
LRRC32_ENST00000404995 LRRC32 Q14392 Transforming growth factor beta activator LRRC32 chr11 GO:0050863 Not Cancer Driver No 130 0.196 28 4 0.143 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0050863 Census Yes 95 0.186 84 12 0.143 0
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:0050863 Census, Compendium Yes 75 0.091 139 12 0.086 1
MAP3K8_ENST00000542547 MAP3K8 P41279 Mitogen-activated protein kinase kinase kinase 8 chr10 GO:0050863 Not Cancer Driver No 58 0.124 109 10 0.092 0
MAPK8IP1 MAPK8IP1 Q9UQF2 C-Jun-amino-terminal kinase-interacting protein 1 chr11 GO:0050863 Not Cancer Driver No 79 0.111 444 40 0.09 1
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0050863 Not Cancer Driver No 15 0.105 20 2 0.1 0
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 GO:0050863 Not Cancer Driver No 74 0.128 274 29 0.106 0
MYB_ENST00000367814 MYB P10242 Transcriptional activator Myb chr6 GO:0050863 Census Yes 82 0.128 528 69 0.131 0
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:0050863 Not Cancer Driver No 247 0.219 51 10 0.196 4
NFKBID NFKBID Q8NI38 NF-kappa-B inhibitor delta chr19 GO:0050863 Not Cancer Driver No 47 0.15 124 20 0.161 0
NFKBIZ NFKBIZ Q9BYH8 NF-kappa-B inhibitor zeta chr3 GO:0050863 Not Cancer Driver No 96 0.134 443 53 0.12 0
NKAP NKAP Q8N5F7 NF-kappa-B-activating protein chrX GO:0050863 Not Cancer Driver No 80 0.193 409 77 0.188 3
NLRP3_ENST00000391828 NLRP3 Q96P20 NACHT, LRR and PYD domains-containing protein 3 chr1 GO:0050863 Not Cancer Driver No 339 0.327 64 33 0.516 37
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0050863 Not Cancer Driver No 169 0.163 40 4 0.1 15
NRARP NRARP Q7Z6K4 Notch-regulated ankyrin repeat-containing protein chr9 GO:0050863 Not Cancer Driver No 9 0.079 11 1 0.091 0
PAG1 PAG1 Q9NWQ8 Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 chr8 GO:0050863 Not Cancer Driver No 58 0.134 394 54 0.137 0
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0050863 Not Cancer Driver No 142 0.228 110 28 0.255 1
PDCD1LG2 PDCD1LG2 Q9BQ51 Programmed cell death 1 ligand 2 chr9 GO:0050863 Census, Compendium Yes 33 0.121 41 13 0.317 0
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0050863 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PNP PNP P00491 Purine nucleoside phosphorylase chr14 GO:0050863 Not Cancer Driver No 38 0.131 29 2 0.069 5
PRDM1 PRDM1 O75626 PR domain zinc finger protein 1 chr6 GO:0050863 Census, Compendium Yes 145 0.176 337 66 0.196 0
PRDX2 PRDX2 P32119 Peroxiredoxin-2 chr19 GO:0050863 Not Cancer Driver No 24 0.121 30 4 0.133 0
PRELID1 PRELID1 Q9Y255 PRELI domain-containing protein 1, mitochondrial chr5 GO:0050863 Not Cancer Driver No 21 0.096 44 2 0.045 0
PRKAR1A_ENST00000536854 PRKAR1A P10644 cAMP-dependent protein kinase type I-alpha regulatory subunit chr17 GO:0050863 Census, Compendium Yes 39 0.102 66 11 0.167 17
PRKCQ PRKCQ Q04759 Protein kinase C theta type chr10 GO:0050863 Not Cancer Driver No 147 0.208 28 9 0.321 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0050863 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRNP PRNP P04156 Major prion protein chr20 GO:0050863 Not Cancer Driver No 36 0.142 115 7 0.061 18
PSG9 PSG9 Q00887 Pregnancy-specific beta-1-glycoprotein 9 chr19 GO:0050863 Not Cancer Driver No 125 0.293 40 8 0.2 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0050863 Census, Compendium Yes 129 0.218 260 38 0.146 60
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:0050863 Not Cancer Driver No 57 0.137 120 14 0.117 0
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0050863 Not Cancer Driver No 141 0.175 364 62 0.17 4
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:0050863 Census, Compendium Yes 73 0.123 192 25 0.13 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0050863 Census, Compendium Yes 315 0.241 462 107 0.232 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0050863 Not Cancer Driver No 16 0.082 39 4 0.103 0
RAG2 RAG2 P55895 V(D)J recombination-activating protein 2 chr11 GO:0050863 Not Cancer Driver No 118 0.224 85 23 0.271 6
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0050863 Census, Compendium Yes 70 0.152 167 14 0.084 0
RASAL3 RASAL3 Q86YV0 RAS protein activator like-3 chr19 GO:0050863 Not Cancer Driver No 114 0.113 536 68 0.127 0
RASGRP1 RASGRP1 O95267 RAS guanyl-releasing protein 1 chr15 GO:0050863 Not Cancer Driver No 96 0.12 191 12 0.063 1
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 GO:0050863 Not Cancer Driver No 158 0.139 796 115 0.144 0
RC3H2_ENST00000357244 RC3H2 Q9HBD1 Roquin-2 chr9 GO:0050863 Not Cancer Driver No 128 0.107 703 81 0.115 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0050863 Census, Compendium Yes 99 0.513 46 13 0.283 2
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0050863 Not Cancer Driver No 63 0.117 143 20 0.14 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:0050863 Not Cancer Driver No 66 0.127 295 39 0.132 0
RIPOR2_ENST00000259698 RIPOR2 Q9Y4F9 Rho family-interacting cell polarization regulator 2 chr6 GO:0050863 Not Cancer Driver No 131 0.123 421 76 0.181 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0050863 Not Cancer Driver No 22 0.091 48 4 0.083 0
RUNX1_ENST00000344691 RUNX1 Q01196 Runt-related transcription factor 1 chr21 GO:0050863 Census, Compendium Yes 81 0.179 360 58 0.161 2
RUNX3_ENST00000308873 RUNX3 Q13761 Runt-related transcription factor 3 chr1 GO:0050863 Not Cancer Driver No 59 0.142 331 45 0.136 0
SART1 SART1 O43290 U4/U6.U5 tri-snRNP-associated protein 1 chr11 GO:0050863 Not Cancer Driver No 71 0.089 685 63 0.092 0
SASH3 SASH3 O75995 SAM and SH3 domain-containing protein 3 chrX GO:0050863 Not Cancer Driver No 59 0.155 327 49 0.15 0
SCRIB_ENST00000320476 SCRIB Q14160 Protein scribble homolog chr8 GO:0050863 Not Cancer Driver No 196 0.12 1064 135 0.127 2
SH3RF1 SH3RF1 Q7Z6J0 E3 ubiquitin-protein ligase SH3RF1 chr4 GO:0050863 Not Cancer Driver No 109 0.123 586 72 0.123 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0050863 Not Cancer Driver No 56 0.121 139 14 0.101 81
SIT1 SIT1 Q9Y3P8 Signaling threshold-regulating transmembrane adapter 1 chr9 GO:0050863 Not Cancer Driver No 21 0.107 122 9 0.074 0
SLAMF1_ENST00000302035 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 GO:0050863 Not Cancer Driver No 82 0.245 64 10 0.156 0
SLC46A2 SLC46A2 Q9BY10 Thymic stromal cotransporter homolog chr9 GO:0050863 Not Cancer Driver No 45 0.095 36 3 0.083 0
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0050863 Not Cancer Driver No 40 0.094 139 0 0.0 0
SOCS1 SOCS1 O15524 Suppressor of cytokine signaling 1 chr16 GO:0050863 Census, Compendium Yes 22 0.104 66 3 0.045 2
SOCS5 SOCS5 O75159 Suppressor of cytokine signaling 5 chr2 GO:0050863 Not Cancer Driver No 84 0.157 297 46 0.155 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0050863 Not Cancer Driver No 16 0.104 93 9 0.097 79
SOS1_ENST00000402219 SOS1 Q07889 Son of sevenless homolog 1 chr2 GO:0050863 Compendium Yes 197 0.148 458 62 0.135 38
SOS2 SOS2 Q07890 Son of sevenless homolog 2 chr14 GO:0050863 Not Cancer Driver No 173 0.13 362 54 0.149 2
SOX12 SOX12 O15370 Transcription factor SOX-12 chr20 GO:0050863 Not Cancer Driver No 20 0.063 307 19 0.062 0
SOX13 SOX13 Q9UN79 Transcription factor SOX-13 chr1 GO:0050863 Not Cancer Driver No 85 0.137 564 77 0.137 0
SOX4 SOX4 Q06945 Transcription factor SOX-4 chr6 GO:0050863 Not Cancer Driver No 28 0.059 400 24 0.06 4
SPINK5_ENST00000256084 SPINK5 Q9NQ38 Serine protease inhibitor Kazal-type 5 chr5 GO:0050863 Not Cancer Driver No 168 0.158 590 102 0.173 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0050863 Census Yes 53 0.099 130 11 0.085 1
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 GO:0050863 Census, Compendium Yes 93 0.118 144 19 0.132 5
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0050863 Census Yes 96 0.151 131 27 0.206 5
TARM1_ENST00000432826 TARM1 B6A8C7 T-cell-interacting, activating receptor on myeloid cells protein 1 chr19 GO:0050863 Not Cancer Driver No 13 0.048 21 1 0.048 0
TBX21 TBX21 Q9UL17 T-box transcription factor TBX21 chr17 GO:0050863 Not Cancer Driver No 70 0.131 348 50 0.144 0
TESPA1 TESPA1 A2RU30 Protein TESPA1 chr12 GO:0050863 Not Cancer Driver No 127 0.244 284 84 0.296 0
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0050863 Census, Compendium Yes 106 0.187 60 16 0.267 25
TMEM131L_ENST00000409663 TMEM131L A2VDJ0 Transmembrane protein 131-like chr4 GO:0050863 Not Cancer Driver No 188 0.117 448 47 0.105 0
TMIGD2 TMIGD2 Q96BF3 Transmembrane and immunoglobulin domain-containing protein 2 chr19 GO:0050863 Not Cancer Driver No 57 0.202 120 32 0.267 0
TNFRSF13C TNFRSF13C Q96RJ3 Tumor necrosis factor receptor superfamily member 13C chr22 GO:0050863 Not Cancer Driver No 17 0.092 128 15 0.117 0
TNFRSF14 TNFRSF14 Q92956 Tumor necrosis factor receptor superfamily member 14 chr1 GO:0050863 Census, Compendium Yes 33 0.117 54 8 0.148 0
TNFSF13B TNFSF13B Q9Y275 Tumor necrosis factor ligand superfamily member 13B chr13 GO:0050863 Not Cancer Driver No 41 0.144 91 15 0.165 0
TNFSF14 TNFSF14 O43557 Tumor necrosis factor ligand superfamily member 14 chr19 GO:0050863 Not Cancer Driver No 58 0.242 18 1 0.056 0
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 GO:0050863 Not Cancer Driver No 28 0.153 1 0 0.0 0
TNFSF9 TNFSF9 P41273 Tumor necrosis factor ligand superfamily member 9 chr19 GO:0050863 Not Cancer Driver No 32 0.126 39 4 0.103 0
TOX TOX O94900 Thymocyte selection-associated high mobility group box protein TOX chr8 GO:0050863 Not Cancer Driver No 112 0.213 494 108 0.219 0
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0050863 Not Cancer Driver No 26 0.083 98 10 0.102 18
TWSG1 TWSG1 Q9GZX9 Twisted gastrulation protein homolog 1 chr18 GO:0050863 Not Cancer Driver No 27 0.121 19 3 0.158 0
TYK2 TYK2 P29597 Non-receptor tyrosine-protein kinase TYK2 chr19 GO:0050863 Not Cancer Driver No 148 0.125 213 29 0.136 0
VAV1 VAV1 P15498 Proto-oncogene vav chr19 GO:0050863 Census, Compendium Yes 165 0.195 113 19 0.168 0
VNN1 VNN1 O95497 Pantetheinase chr6 GO:0050863 Not Cancer Driver No 88 0.172 20 5 0.25 0
VSIR VSIR Q9H7M9 V-type immunoglobulin domain-containing suppressor of T-cell activation chr10 GO:0050863 Not Cancer Driver No 52 0.167 135 19 0.141 0
XCL1 XCL1 P47992 Lymphotactin chr1 GO:0050863 Not Cancer Driver No 28 0.246 35 11 0.314 0
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 GO:0050863 Not Cancer Driver No 65 0.12 62 10 0.161 0
ZAP70 ZAP70 P43403 Tyrosine-protein kinase ZAP-70 chr2 GO:0050863 Not Cancer Driver No 126 0.204 117 17 0.145 8
ZBTB1 ZBTB1 Q9Y2K1 Zinc finger and BTB domain-containing protein 1 chr14 GO:0050863 Not Cancer Driver No 70 0.098 271 27 0.1 0
ZBTB16_ENST00000392996 ZBTB16 Q05516 Zinc finger and BTB domain-containing protein 16 chr11 GO:0050863 Census, Compendium Yes 131 0.195 268 50 0.187 1
ZBTB7B_ENST00000368426 ZBTB7B O15156 Zinc finger and BTB domain-containing protein 7B chr1 GO:0050863 Compendium Yes 103 0.191 353 70 0.198 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0050863 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZC3H8 ZC3H8 Q8N5P1 Zinc finger CCCH domain-containing protein 8 chr2 GO:0050863 Not Cancer Driver No 22 0.076 187 17 0.091 0
ZEB1_ENST00000320985 ZEB1 P37275 Zinc finger E-box-binding homeobox 1 chr10 GO:0050863 Census, Compendium Yes 246 0.219 831 200 0.241 8
ZNF683 ZNF683 Q8IZ20 Tissue-resident T-cell transcription regulator protein ZNF683 chr1 GO:0050863 Not Cancer Driver No 103 0.197 202 32 0.158 0