Total number of protein in "GO:0050830" GO term: 96
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACP5_ENST00000433365 | ACP5 | P13686 | Tartrate-resistant acid phosphatase type 5 | chr19 | GO:0050830 | Not Cancer Driver | No | 51 | 0.157 | 31 | 6 | 0.194 | 8 |
| ADAM17 | ADAM17 | P78536 | Disintegrin and metalloproteinase domain-containing protein 17 | chr2 | GO:0050830 | Not Cancer Driver | No | 80 | 0.097 | 182 | 17 | 0.093 | 0 |
| ANG | ANG | P03950 | Angiogenin | chr14 | GO:0050830 | Not Cancer Driver | No | 19 | 0.129 | 36 | 2 | 0.056 | 14 |
| C10orf99 | GPR15L | Q6UWK7 | Protein GPR15L | chr10 | GO:0050830 | Not Cancer Driver | No | 11 | 0.136 | 0 | 0 | 0.0 | 0 |
| C5AR1 | C5AR1 | P21730 | C5a anaphylatoxin chemotactic receptor 1 | chr19 | GO:0050830 | Not Cancer Driver | No | 71 | 0.203 | 0 | 0 | 0.0 | 0 |
| CAMP | CAMP | P49913 | Cathelicidin antimicrobial peptide | chr3 | GO:0050830 | Not Cancer Driver | No | 25 | 0.147 | 48 | 4 | 0.083 | 0 |
| CARD9 | CARD9 | Q9H257 | Caspase recruitment domain-containing protein 9 | chr9 | GO:0050830 | Not Cancer Driver | No | 72 | 0.134 | 225 | 35 | 0.156 | 11 |
| CD36_ENST00000309881 | CD36 | P16671 | Platelet glycoprotein 4 | chr7 | GO:0050830 | Not Cancer Driver | No | 75 | 0.159 | 12 | 3 | 0.25 | 3 |
| CHGA | CHGA | P10645 | Chromogranin-A | chr14 | GO:0050830 | Not Cancer Driver | No | 46 | 0.101 | 421 | 44 | 0.105 | 0 |
| CRP | CRP | P02741 | C-reactive protein | chr1 | GO:0050830 | Not Cancer Driver | No | 59 | 0.263 | 0 | 0 | 0.0 | 0 |
| CTSG | CTSG | P08311 | Cathepsin G | chr14 | GO:0050830 | Not Cancer Driver | No | 65 | 0.255 | 80 | 29 | 0.362 | 0 |
| DEFA3 | DEFA3 | P59666 | Neutrophil defensin 3 | chr8 | GO:0050830 | Not Cancer Driver | No | 15 | 0.16 | 0 | 0 | 0.0 | 0 |
| DEFA4 | DEFA4 | P12838 | Defensin alpha 4 | chr8 | GO:0050830 | Not Cancer Driver | No | 35 | 0.361 | 17 | 5 | 0.294 | 0 |
| DEFA5 | DEFA5 | Q01523 | Defensin-5 | chr8 | GO:0050830 | Not Cancer Driver | No | 16 | 0.17 | 17 | 3 | 0.176 | 0 |
| DEFA6 | DEFA6 | Q01524 | Defensin-6 | chr8 | GO:0050830 | Not Cancer Driver | No | 19 | 0.19 | 15 | 2 | 0.133 | 0 |
| DEFB1 | DEFB1 | P60022 | Beta-defensin 1 | chr8 | GO:0050830 | Not Cancer Driver | No | 8 | 0.118 | 0 | 0 | 0.0 | 0 |
| DEFB104B | DEFB104B | Q8WTQ1 | Beta-defensin 104 | chr8 | GO:0050830 | Not Cancer Driver | No | 1 | 0.014 | 0 | 0 | 0.0 | 0 |
| DEFB106B | DEFB106B | Q8N104 | Beta-defensin 106 | chr8 | GO:0050830 | Not Cancer Driver | No | 15 | 0.231 | 0 | 0 | 0.0 | 0 |
| DEFB107B | DEFB107B | Q8IZN7 | Beta-defensin 107 | chr8 | GO:0050830 | Not Cancer Driver | No | 1 | 0.014 | 0 | 0 | 0.0 | 0 |
| DEFB114 | DEFB114 | Q30KQ6 | Beta-defensin 114 | chr6 | GO:0050830 | Not Cancer Driver | No | 31 | 0.449 | 0 | 0 | 0.0 | 0 |
| DEFB119_ENST00000376321 | DEFB119 | Q8N690 | Beta-defensin 119 | chr20 | GO:0050830 | Not Cancer Driver | No | 25 | 0.298 | 0 | 0 | 0.0 | 0 |
| DEFB128 | DEFB128 | Q7Z7B8 | Beta-defensin 128 | chr20 | GO:0050830 | Not Cancer Driver | No | 11 | 0.118 | 4 | 0 | 0.0 | 0 |
| DEFB4B | DEFB4B | O15263 | Beta-defensin 4A | chr8 | GO:0050830 | Not Cancer Driver | No | 1 | 0.016 | 0 | 0 | 0.0 | 0 |
| DMBT1_ENST00000619379 | DMBT1 | Q9UGM3 | Deleted in malignant brain tumors 1 protein | chr10 | GO:0050830 | Not Cancer Driver | No | 506 | 0.21 | 404 | 64 | 0.158 | 0 |
| DROSHA_ENST00000344624 | DROSHA | Q9NRR4 | Ribonuclease 3 | chr5 | GO:0050830 | Census, Compendium | Yes | 175 | 0.127 | 682 | 100 | 0.147 | 0 |
| EPHA2 | EPHA2 | P29317 | Ephrin type-A receptor 2 | chr1 | GO:0050830 | Compendium | Yes | 171 | 0.175 | 187 | 39 | 0.209 | 3 |
| FCN2 | FCN2 | Q15485 | Ficolin-2 | chr9 | GO:0050830 | Not Cancer Driver | No | 73 | 0.233 | 80 | 19 | 0.237 | 0 |
| FGR_ENST00000374004 | FGR | P09769 | Tyrosine-protein kinase Fgr | chr1 | GO:0050830 | Not Cancer Driver | No | 85 | 0.161 | 52 | 8 | 0.154 | 0 |
| GBP2 | GBP2 | P32456 | Guanylate-binding protein 2 | chr1 | GO:0050830 | Not Cancer Driver | No | 75 | 0.127 | 134 | 15 | 0.112 | 0 |
| GBP4 | GBP4 | Q96PP9 | Guanylate-binding protein 4 | chr1 | GO:0050830 | Not Cancer Driver | No | 114 | 0.178 | 165 | 31 | 0.188 | 0 |
| GBP6 | GBP6 | Q6ZN66 | Guanylate-binding protein 6 | chr1 | GO:0050830 | Not Cancer Driver | No | 112 | 0.177 | 157 | 21 | 0.134 | 0 |
| GBP7 | GBP7 | Q8N8V2 | Guanylate-binding protein 7 | chr1 | GO:0050830 | Not Cancer Driver | No | 88 | 0.138 | 93 | 8 | 0.086 | 0 |
| GSDMD_ENST00000262580 | GSDMD | P57764 | Gasdermin-D | chr8 | GO:0050830 | Not Cancer Driver | No | 47 | 0.097 | 156 | 16 | 0.103 | 0 |
| H2BFS | H2BC12L | P57053 | Histone H2B type F-S | chr21 | GO:0050830 | Not Cancer Driver | No | 1 | 0.008 | 86 | 1 | 0.012 | 0 |
| HAVCR2 | HAVCR2 | Q8TDQ0 | Hepatitis A virus cellular receptor 2 | chr5 | GO:0050830 | Not Cancer Driver | No | 69 | 0.229 | 17 | 2 | 0.118 | 3 |
| HIST1H2BC | H2BC10 | P62807 | Histone H2B type 1-C/E/F/G/I | chr6 | GO:0050830 | Not Cancer Driver | No | 53 | 0.421 | 79 | 27 | 0.342 | 0 |
| HIST1H2BE | H2BC10 | P62807 | Histone H2B type 1-C/E/F/G/I | chr6 | GO:0050830 | Not Cancer Driver | No | 26 | 0.206 | 79 | 16 | 0.203 | 0 |
| HIST1H2BF | H2BC10 | P62807 | Histone H2B type 1-C/E/F/G/I | chr6 | GO:0050830 | Not Cancer Driver | No | 30 | 0.238 | 79 | 20 | 0.253 | 0 |
| HIST1H2BG | H2BC10 | P62807 | Histone H2B type 1-C/E/F/G/I | chr6 | GO:0050830 | Not Cancer Driver | No | 45 | 0.357 | 79 | 25 | 0.316 | 0 |
| HIST1H2BI | H2BC10 | P62807 | Histone H2B type 1-C/E/F/G/I | chr6 | GO:0050830 | Not Cancer Driver | No | 30 | 0.238 | 79 | 18 | 0.228 | 0 |
| HIST1H2BJ_ENST00000339812 | H2BC11 | P06899 | Histone H2B type 1-J | chr6 | GO:0050830 | Not Cancer Driver | No | 22 | 0.175 | 75 | 13 | 0.173 | 0 |
| HIST1H2BK | H2BC12 | O60814 | Histone H2B type 1-K | chr6 | GO:0050830 | Not Cancer Driver | No | 42 | 0.333 | 78 | 29 | 0.372 | 0 |
| HIST2H2BE | H2BC21 | Q16778 | Histone H2B type 2-E | chr1 | GO:0050830 | Not Cancer Driver | No | 47 | 0.373 | 77 | 30 | 0.39 | 0 |
| HLA-A_ENST00000376809 | HLA-A | P04439 | HLA class I histocompatibility antigen, A alpha chain | chr6 | GO:0050830 | Census, Compendium | Yes | 128 | 0.351 | 125 | 60 | 0.48 | 0 |
| HLA-E | HLA-E | P13747 | HLA class I histocompatibility antigen, alpha chain E | chr6 | GO:0050830 | Not Cancer Driver | No | 63 | 0.176 | 138 | 39 | 0.283 | 0 |
| HMGB2 | HMGB2 | P26583 | High mobility group protein B2 | chr4 | GO:0050830 | Not Cancer Driver | No | 38 | 0.182 | 207 | 38 | 0.184 | 0 |
| IL17A | IL17A | Q16552 | Interleukin-17A | chr6 | GO:0050830 | Not Cancer Driver | No | 52 | 0.335 | 56 | 21 | 0.375 | 0 |
| IL17F | IL17F | Q96PD4 | Interleukin-17F | chr6 | GO:0050830 | Not Cancer Driver | No | 42 | 0.258 | 34 | 11 | 0.324 | 1 |
| IL27RA | IL27RA | Q6UWB1 | Interleukin-27 receptor subunit alpha | chr19 | GO:0050830 | Not Cancer Driver | No | 91 | 0.143 | 167 | 23 | 0.138 | 0 |
| IL6 | IL6 | P05231 | Interleukin-6 | chr7 | GO:0050830 | Not Cancer Driver | No | 35 | 0.165 | 58 | 7 | 0.121 | 0 |
| IL7R | IL7R | P16871 | Interleukin-7 receptor subunit alpha | chr5 | GO:0050830 | Census, Compendium | Yes | 177 | 0.386 | 88 | 48 | 0.545 | 1 |
| KLRK1 | KLRK1 | P26718 | NKG2-D type II integral membrane protein | chr12 | GO:0050830 | Not Cancer Driver | No | 38 | 0.176 | 0 | 0 | 0.0 | 0 |
| KRT6A | KRT6A | P02538 | Keratin, type II cytoskeletal 6A | chr12 | GO:0050830 | Not Cancer Driver | No | 127 | 0.225 | 138 | 35 | 0.254 | 24 |
| LBP | LBP | P18428 | Lipopolysaccharide-binding protein | chr20 | GO:0050830 | Not Cancer Driver | No | 84 | 0.175 | 6 | 0 | 0.0 | 0 |
| LCE3A | LCE3A | Q5TA76 | Late cornified envelope protein 3A | chr1 | GO:0050830 | Not Cancer Driver | No | 23 | 0.258 | 0 | 0 | 0.0 | 0 |
| LCE3B | LCE3B | Q5TA77 | Late cornified envelope protein 3B | chr1 | GO:0050830 | Not Cancer Driver | No | 10 | 0.105 | 0 | 0 | 0.0 | 0 |
| LCE3C | LCE3C | Q5T5A8 | Late cornified envelope protein 3C | chr1 | GO:0050830 | Not Cancer Driver | No | 9 | 0.096 | 0 | 0 | 0.0 | 0 |
| LTA | LTA | P01374 | Lymphotoxin-alpha | chr6 | GO:0050830 | Not Cancer Driver | No | 37 | 0.18 | 20 | 5 | 0.25 | 0 |
| LYG1 | LYG1 | Q8N1E2 | Lysozyme g-like protein 1 | chr2 | GO:0050830 | Not Cancer Driver | No | 18 | 0.093 | 36 | 4 | 0.111 | 0 |
| LYG2 | LYG2 | Q86SG7 | Lysozyme g-like protein 2 | chr2 | GO:0050830 | Not Cancer Driver | No | 38 | 0.179 | 1 | 1 | 1.0 | 0 |
| LYZ | LYZ | P61626 | Lysozyme C | chr12 | GO:0050830 | Not Cancer Driver | No | 26 | 0.176 | 0 | 0 | 0.0 | 2 |
| MBL2 | MBL2 | P11226 | Mannose-binding protein C | chr10 | GO:0050830 | Not Cancer Driver | No | 63 | 0.254 | 122 | 32 | 0.262 | 0 |
| MPEG1 | MPEG1 | Q2M385 | Macrophage-expressed gene 1 protein | chr11 | GO:0050830 | Not Cancer Driver | No | 134 | 0.187 | 101 | 21 | 0.208 | 0 |
| MR1 | MR1 | Q95460 | Major histocompatibility complex class I-related gene protein | chr1 | GO:0050830 | Not Cancer Driver | No | 60 | 0.176 | 33 | 7 | 0.212 | 0 |
| MYD88_ENST00000396334 | MYD88 | Q99836 | Myeloid differentiation primary response protein MyD88 | chr3 | GO:0050830 | Census, Compendium | Yes | 37 | 0.125 | 47 | 1 | 0.021 | 2 |
| NOD1 | NOD1 | Q9Y239 | Nucleotide-binding oligomerization domain-containing protein 1 | chr7 | GO:0050830 | Not Cancer Driver | No | 130 | 0.136 | 38 | 7 | 0.184 | 0 |
| NOD2 | NOD2 | Q9HC29 | Nucleotide-binding oligomerization domain-containing protein 2 | chr16 | GO:0050830 | Not Cancer Driver | No | 169 | 0.163 | 40 | 4 | 0.1 | 15 |
| P2RX7 | P2RX7 | Q99572 | P2X purinoceptor 7 | chr12 | GO:0050830 | Not Cancer Driver | No | 51 | 0.086 | 14 | 2 | 0.143 | 0 |
| PGLYRP1 | PGLYRP1 | O75594 | Peptidoglycan recognition protein 1 | chr19 | GO:0050830 | Not Cancer Driver | No | 34 | 0.173 | 4 | 0 | 0.0 | 0 |
| PGLYRP2 | PGLYRP2 | Q96PD5 | N-acetylmuramoyl-L-alanine amidase | chr19 | GO:0050830 | Not Cancer Driver | No | 111 | 0.193 | 160 | 28 | 0.175 | 0 |
| PGLYRP3 | PGLYRP3 | Q96LB9 | Peptidoglycan recognition protein 3 | chr1 | GO:0050830 | Not Cancer Driver | No | 81 | 0.238 | 0 | 0 | 0.0 | 0 |
| PGLYRP4 | PGLYRP4 | Q96LB8 | Peptidoglycan recognition protein 4 | chr1 | GO:0050830 | Not Cancer Driver | No | 81 | 0.217 | 4 | 1 | 0.25 | 0 |
| PLA2G1B | PLA2G1B | P04054 | Phospholipase A2 | chr12 | GO:0050830 | Not Cancer Driver | No | 17 | 0.115 | 0 | 0 | 0.0 | 0 |
| PLA2G2A_ENST00000375111 | PLA2G2A | P14555 | Phospholipase A2, membrane associated | chr1 | GO:0050830 | Not Cancer Driver | No | 25 | 0.174 | 0 | 0 | 0.0 | 0 |
| PPP1R11 | PPP1R11 | O60927 | E3 ubiquitin-protein ligase PPP1R11 | chr6 | GO:0050830 | Not Cancer Driver | No | 17 | 0.135 | 126 | 17 | 0.135 | 0 |
| PYCARD | PYCARD | Q9ULZ3 | Apoptosis-associated speck-like protein containing a CARD | chr16 | GO:0050830 | Not Cancer Driver | No | 16 | 0.082 | 39 | 4 | 0.103 | 0 |
| RARRES2 | RARRES2 | Q99969 | Retinoic acid receptor responder protein 2 | chr7 | GO:0050830 | Not Cancer Driver | No | 16 | 0.098 | 14 | 2 | 0.143 | 0 |
| REG3G | REG3G | Q6UW15 | Regenerating islet-derived protein 3-gamma | chr2 | GO:0050830 | Not Cancer Driver | No | 81 | 0.463 | 17 | 4 | 0.235 | 0 |
| RIPK2 | RIPK2 | O43353 | Receptor-interacting serine/threonine-protein kinase 2 | chr8 | GO:0050830 | Not Cancer Driver | No | 63 | 0.117 | 143 | 20 | 0.14 | 0 |
| RNASE2 | RNASE2 | P10153 | Non-secretory ribonuclease | chr14 | GO:0050830 | Not Cancer Driver | No | 30 | 0.186 | 20 | 4 | 0.2 | 0 |
| RNASE3 | RNASE3 | P12724 | Eosinophil cationic protein | chr14 | GO:0050830 | Not Cancer Driver | No | 37 | 0.231 | 8 | 0 | 0.0 | 0 |
| RNASE6 | RNASE6 | Q93091 | Ribonuclease K6 | chr14 | GO:0050830 | Not Cancer Driver | No | 26 | 0.173 | 0 | 0 | 0.0 | 0 |
| RNASE7 | RNASE7 | Q9H1E1 | Ribonuclease 7 | chr14 | GO:0050830 | Not Cancer Driver | No | 27 | 0.173 | 42 | 4 | 0.095 | 0 |
| RNASE8 | RNASE8 | Q8TDE3 | Ribonuclease 8 | chr14 | GO:0050830 | Not Cancer Driver | No | 18 | 0.117 | 17 | 2 | 0.118 | 0 |
| ROMO1_ENST00000397416 | ROMO1 | P60602 | Reactive oxygen species modulator 1 | chr20 | GO:0050830 | Not Cancer Driver | No | 9 | 0.114 | 0 | 0 | 0.0 | 0 |
| RPL39 | RPL39 | P62891 | 60S ribosomal protein L39 | chrX | GO:0050830 | Not Cancer Driver | No | 9 | 0.176 | 51 | 9 | 0.176 | 0 |
| SEH1L_ENST00000262124 | SEH1L | Q96EE3 | Nucleoporin SEH1 | chr18 | GO:0050830 | Not Cancer Driver | No | 40 | 0.111 | 71 | 11 | 0.155 | 0 |
| SSC5D | SSC5D | A1L4H1 | Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D | chr19 | GO:0050830 | Not Cancer Driver | No | 81 | 0.051 | 1194 | 70 | 0.059 | 0 |
| STAB2 | STAB2 | Q8WWQ8 | Stabilin-2 | chr12 | GO:0050830 | Not Cancer Driver | No | 482 | 0.189 | 101 | 16 | 0.158 | 0 |
| TBK1 | TBK1 | Q9UHD2 | Serine/threonine-protein kinase TBK1 | chr12 | GO:0050830 | Not Cancer Driver | No | 101 | 0.139 | 42 | 5 | 0.119 | 12 |
| TIRAP_ENST00000392680 | TIRAP | P58753 | Toll/interleukin-1 receptor domain-containing adapter protein | chr11 | GO:0050830 | Not Cancer Driver | No | 28 | 0.127 | 80 | 6 | 0.075 | 0 |
| TLR2 | TLR2 | O60603 | Toll-like receptor 2 | chr4 | GO:0050830 | Not Cancer Driver | No | 108 | 0.138 | 0 | 0 | 0.0 | 0 |
| TNF | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0050830 | Not Cancer Driver | No | 24 | 0.103 | 45 | 3 | 0.067 | 0 |
| TNFRSF14 | TNFRSF14 | Q92956 | Tumor necrosis factor receptor superfamily member 14 | chr1 | GO:0050830 | Census, Compendium | Yes | 33 | 0.117 | 54 | 8 | 0.148 | 0 |
| TNFSF8 | TNFSF8 | P32971 | Tumor necrosis factor ligand superfamily member 8 | chr9 | GO:0050830 | Not Cancer Driver | No | 34 | 0.145 | 30 | 2 | 0.067 | 0 |
| ZG16 | ZG16 | O60844 | Zymogen granule membrane protein 16 | chr16 | GO:0050830 | Not Cancer Driver | No | 5 | 0.03 | 7 | 1 | 0.143 | 0 |