Total number of protein in "GO:0050829" GO term: 76
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADGRB1_ENST00000323289 | ADGRB1 | O14514 | Adhesion G protein-coupled receptor B1 | chr8 | GO:0050829 | Compendium | Yes | 213 | 0.134 | 485 | 47 | 0.097 | 0 |
| AQP1 | AQP1 | P29972 | Aquaporin-1 | chr7 | GO:0050829 | Not Cancer Driver | No | 39 | 0.145 | 4 | 1 | 0.25 | 0 |
| AZU1 | AZU1 | P20160 | Azurocidin | chr19 | GO:0050829 | Not Cancer Driver | No | 42 | 0.167 | 53 | 13 | 0.245 | 0 |
| BPI | BPI | P17213 | Bactericidal permeability-increasing protein | chr20 | GO:0050829 | Not Cancer Driver | No | 90 | 0.185 | 49 | 7 | 0.143 | 0 |
| CAMP | CAMP | P49913 | Cathelicidin antimicrobial peptide | chr3 | GO:0050829 | Not Cancer Driver | No | 25 | 0.147 | 48 | 4 | 0.083 | 0 |
| CD160_ENST00000369288 | CD160 | O95971 | CD160 antigen | chr1 | GO:0050829 | Not Cancer Driver | No | 20 | 0.11 | 2 | 0 | 0.0 | 0 |
| CD4 | CD4 | P01730 | T-cell surface glycoprotein CD4 | chr12 | GO:0050829 | Not Cancer Driver | No | 69 | 0.151 | 56 | 11 | 0.196 | 0 |
| CHGA | CHGA | P10645 | Chromogranin-A | chr14 | GO:0050829 | Not Cancer Driver | No | 46 | 0.101 | 421 | 44 | 0.105 | 0 |
| CST11 | CST11 | Q9H112 | Cystatin-11 | chr20 | GO:0050829 | Not Cancer Driver | No | 38 | 0.275 | 6 | 0 | 0.0 | 0 |
| CTSG | CTSG | P08311 | Cathepsin G | chr14 | GO:0050829 | Not Cancer Driver | No | 65 | 0.255 | 80 | 29 | 0.362 | 0 |
| DEFA3 | DEFA3 | P59666 | Neutrophil defensin 3 | chr8 | GO:0050829 | Not Cancer Driver | No | 15 | 0.16 | 0 | 0 | 0.0 | 0 |
| DEFA4 | DEFA4 | P12838 | Defensin alpha 4 | chr8 | GO:0050829 | Not Cancer Driver | No | 35 | 0.361 | 17 | 5 | 0.294 | 0 |
| DEFA5 | DEFA5 | Q01523 | Defensin-5 | chr8 | GO:0050829 | Not Cancer Driver | No | 16 | 0.17 | 17 | 3 | 0.176 | 0 |
| DEFA6 | DEFA6 | Q01524 | Defensin-6 | chr8 | GO:0050829 | Not Cancer Driver | No | 19 | 0.19 | 15 | 2 | 0.133 | 0 |
| DEFB1 | DEFB1 | P60022 | Beta-defensin 1 | chr8 | GO:0050829 | Not Cancer Driver | No | 8 | 0.118 | 0 | 0 | 0.0 | 0 |
| DEFB104B | DEFB104B | Q8WTQ1 | Beta-defensin 104 | chr8 | GO:0050829 | Not Cancer Driver | No | 1 | 0.014 | 0 | 0 | 0.0 | 0 |
| DEFB106B | DEFB106B | Q8N104 | Beta-defensin 106 | chr8 | GO:0050829 | Not Cancer Driver | No | 15 | 0.231 | 0 | 0 | 0.0 | 0 |
| DEFB107B | DEFB107B | Q8IZN7 | Beta-defensin 107 | chr8 | GO:0050829 | Not Cancer Driver | No | 1 | 0.014 | 0 | 0 | 0.0 | 0 |
| DEFB114 | DEFB114 | Q30KQ6 | Beta-defensin 114 | chr6 | GO:0050829 | Not Cancer Driver | No | 31 | 0.449 | 0 | 0 | 0.0 | 0 |
| DEFB118 | DEFB118 | Q96PH6 | Defensin beta 118 | chr20 | GO:0050829 | Not Cancer Driver | No | 40 | 0.325 | 45 | 16 | 0.356 | 0 |
| DEFB119_ENST00000376321 | DEFB119 | Q8N690 | Beta-defensin 119 | chr20 | GO:0050829 | Not Cancer Driver | No | 25 | 0.298 | 0 | 0 | 0.0 | 0 |
| DEFB126 | DEFB126 | Q9BYW3 | Beta-defensin 126 | chr20 | GO:0050829 | Not Cancer Driver | No | 24 | 0.216 | 16 | 7 | 0.438 | 0 |
| DEFB127 | DEFB127 | Q9H1M4 | Beta-defensin 127 | chr20 | GO:0050829 | Not Cancer Driver | No | 27 | 0.273 | 1 | 0 | 0.0 | 0 |
| DEFB128 | DEFB128 | Q7Z7B8 | Beta-defensin 128 | chr20 | GO:0050829 | Not Cancer Driver | No | 11 | 0.118 | 4 | 0 | 0.0 | 0 |
| DEFB132 | DEFB132 | Q7Z7B7 | Beta-defensin 132 | chr20 | GO:0050829 | Not Cancer Driver | No | 6 | 0.063 | 24 | 1 | 0.042 | 0 |
| DEFB4B | DEFB4B | O15263 | Beta-defensin 4A | chr8 | GO:0050829 | Not Cancer Driver | No | 1 | 0.016 | 0 | 0 | 0.0 | 0 |
| DMBT1_ENST00000619379 | DMBT1 | Q9UGM3 | Deleted in malignant brain tumors 1 protein | chr10 | GO:0050829 | Not Cancer Driver | No | 506 | 0.21 | 404 | 64 | 0.158 | 0 |
| DROSHA_ENST00000344624 | DROSHA | Q9NRR4 | Ribonuclease 3 | chr5 | GO:0050829 | Census, Compendium | Yes | 175 | 0.127 | 682 | 100 | 0.147 | 0 |
| FCN2 | FCN2 | Q15485 | Ficolin-2 | chr9 | GO:0050829 | Not Cancer Driver | No | 73 | 0.233 | 80 | 19 | 0.237 | 0 |
| GALP | GALP | Q9UBC7 | Galanin-like peptide | chr19 | GO:0050829 | Not Cancer Driver | No | 35 | 0.302 | 41 | 15 | 0.366 | 0 |
| GSDMD_ENST00000262580 | GSDMD | P57764 | Gasdermin-D | chr8 | GO:0050829 | Not Cancer Driver | No | 47 | 0.097 | 156 | 16 | 0.103 | 0 |
| HIST1H2BJ_ENST00000339812 | H2BC11 | P06899 | Histone H2B type 1-J | chr6 | GO:0050829 | Not Cancer Driver | No | 22 | 0.175 | 75 | 13 | 0.173 | 0 |
| HIST1H2BK | H2BC12 | O60814 | Histone H2B type 1-K | chr6 | GO:0050829 | Not Cancer Driver | No | 42 | 0.333 | 78 | 29 | 0.372 | 0 |
| HMGB2 | HMGB2 | P26583 | High mobility group protein B2 | chr4 | GO:0050829 | Not Cancer Driver | No | 38 | 0.182 | 207 | 38 | 0.184 | 0 |
| IL12B | IL12B | P29460 | Interleukin-12 subunit beta | chr5 | GO:0050829 | Not Cancer Driver | No | 48 | 0.146 | 42 | 2 | 0.048 | 0 |
| IL17A | IL17A | Q16552 | Interleukin-17A | chr6 | GO:0050829 | Not Cancer Driver | No | 52 | 0.335 | 56 | 21 | 0.375 | 0 |
| IL17F | IL17F | Q96PD4 | Interleukin-17F | chr6 | GO:0050829 | Not Cancer Driver | No | 42 | 0.258 | 34 | 11 | 0.324 | 1 |
| IL22RA1 | IL22RA1 | Q8N6P7 | Interleukin-22 receptor subunit alpha-1 | chr1 | GO:0050829 | Not Cancer Driver | No | 66 | 0.115 | 297 | 37 | 0.125 | 0 |
| IL23A | IL23A | Q9NPF7 | Interleukin-23 subunit alpha | chr12 | GO:0050829 | Not Cancer Driver | No | 15 | 0.079 | 42 | 3 | 0.071 | 0 |
| IL23R | IL23R | Q5VWK5 | Interleukin-23 receptor | chr1 | GO:0050829 | Not Cancer Driver | No | 70 | 0.111 | 117 | 19 | 0.162 | 0 |
| IL6 | IL6 | P05231 | Interleukin-6 | chr7 | GO:0050829 | Not Cancer Driver | No | 35 | 0.165 | 58 | 7 | 0.121 | 0 |
| IL6R | IL6R | P08887 | Interleukin-6 receptor subunit alpha | chr1 | GO:0050829 | Not Cancer Driver | No | 55 | 0.118 | 165 | 23 | 0.139 | 1 |
| IRGM | IRGM | A1A4Y4 | Immunity-related GTPase family M protein | chr5 | GO:0050829 | Not Cancer Driver | No | 9 | 0.05 | 45 | 1 | 0.022 | 0 |
| LBP | LBP | P18428 | Lipopolysaccharide-binding protein | chr20 | GO:0050829 | Not Cancer Driver | No | 84 | 0.175 | 6 | 0 | 0.0 | 0 |
| LCE3A | LCE3A | Q5TA76 | Late cornified envelope protein 3A | chr1 | GO:0050829 | Not Cancer Driver | No | 23 | 0.258 | 0 | 0 | 0.0 | 0 |
| LCE3B | LCE3B | Q5TA77 | Late cornified envelope protein 3B | chr1 | GO:0050829 | Not Cancer Driver | No | 10 | 0.105 | 0 | 0 | 0.0 | 0 |
| LCE3C | LCE3C | Q5T5A8 | Late cornified envelope protein 3C | chr1 | GO:0050829 | Not Cancer Driver | No | 9 | 0.096 | 0 | 0 | 0.0 | 0 |
| LTF | LTF | P02788 | Lactotransferrin | chr3 | GO:0050829 | Not Cancer Driver | No | 131 | 0.185 | 21 | 4 | 0.19 | 0 |
| LYPD8 | LYPD8 | Q6UX82 | Ly6/PLAUR domain-containing protein 8 | chr1 | GO:0050829 | Not Cancer Driver | No | 2 | 0.008 | 7 | 0 | 0.0 | 0 |
| LYZ | LYZ | P61626 | Lysozyme C | chr12 | GO:0050829 | Not Cancer Driver | No | 26 | 0.176 | 0 | 0 | 0.0 | 2 |
| MPEG1 | MPEG1 | Q2M385 | Macrophage-expressed gene 1 protein | chr11 | GO:0050829 | Not Cancer Driver | No | 134 | 0.187 | 101 | 21 | 0.208 | 0 |
| MR1 | MR1 | Q95460 | Major histocompatibility complex class I-related gene protein | chr1 | GO:0050829 | Not Cancer Driver | No | 60 | 0.176 | 33 | 7 | 0.212 | 0 |
| NLRP10 | NLRP10 | Q86W26 | NACHT, LRR and PYD domains-containing protein 10 | chr11 | GO:0050829 | Not Cancer Driver | No | 201 | 0.307 | 96 | 34 | 0.354 | 0 |
| NOS2 | NOS2 | P35228 | Nitric oxide synthase, inducible | chr17 | GO:0050829 | Not Cancer Driver | No | 207 | 0.18 | 201 | 33 | 0.164 | 0 |
| OPTN_ENST00000263036 | OPTN | Q96CV9 | Optineurin | chr10 | GO:0050829 | Not Cancer Driver | No | 58 | 0.101 | 470 | 51 | 0.109 | 6 |
| PRB3_ENST00000381842 | PRB3 | Q04118 | Basic salivary proline-rich protein 3 | chr12 | GO:0050829 | Not Cancer Driver | No | 108 | 0.35 | 309 | 108 | 0.35 | 0 |
| PRKD1_ENST00000616995 | PRKD1 | Q15139 | Serine/threonine-protein kinase D1 | chr14 | GO:0050829 | Census | Yes | 201 | 0.22 | 189 | 33 | 0.175 | 2 |
| PYCARD | PYCARD | Q9ULZ3 | Apoptosis-associated speck-like protein containing a CARD | chr16 | GO:0050829 | Not Cancer Driver | No | 16 | 0.082 | 39 | 4 | 0.103 | 0 |
| RARRES2 | RARRES2 | Q99969 | Retinoic acid receptor responder protein 2 | chr7 | GO:0050829 | Not Cancer Driver | No | 16 | 0.098 | 14 | 2 | 0.143 | 0 |
| RNASE2 | RNASE2 | P10153 | Non-secretory ribonuclease | chr14 | GO:0050829 | Not Cancer Driver | No | 30 | 0.186 | 20 | 4 | 0.2 | 0 |
| RNASE3 | RNASE3 | P12724 | Eosinophil cationic protein | chr14 | GO:0050829 | Not Cancer Driver | No | 37 | 0.231 | 8 | 0 | 0.0 | 0 |
| RNASE6 | RNASE6 | Q93091 | Ribonuclease K6 | chr14 | GO:0050829 | Not Cancer Driver | No | 26 | 0.173 | 0 | 0 | 0.0 | 0 |
| RNASE7 | RNASE7 | Q9H1E1 | Ribonuclease 7 | chr14 | GO:0050829 | Not Cancer Driver | No | 27 | 0.173 | 42 | 4 | 0.095 | 0 |
| RNASE8 | RNASE8 | Q8TDE3 | Ribonuclease 8 | chr14 | GO:0050829 | Not Cancer Driver | No | 18 | 0.117 | 17 | 2 | 0.118 | 0 |
| ROMO1_ENST00000397416 | ROMO1 | P60602 | Reactive oxygen species modulator 1 | chr20 | GO:0050829 | Not Cancer Driver | No | 9 | 0.114 | 0 | 0 | 0.0 | 0 |
| RPL30 | RPL30 | P62888 | 60S ribosomal protein L30 | chr8 | GO:0050829 | Not Cancer Driver | No | 4 | 0.035 | 11 | 0 | 0.0 | 0 |
| RPS19_ENST00000600467 | RPS19 | P39019 | 40S ribosomal protein S19 | chr19 | GO:0050829 | Not Cancer Driver | No | 15 | 0.103 | 61 | 3 | 0.049 | 23 |
| S100A7_ENST00000368722 | S100A7 | P31151 | Protein S100-A7 | chr1 | GO:0050829 | Census | Yes | 39 | 0.386 | 28 | 14 | 0.5 | 0 |
| SELP | SELP | P16109 | P-selectin | chr1 | GO:0050829 | Not Cancer Driver | No | 226 | 0.272 | 14 | 2 | 0.143 | 0 |
| SERPINE1 | SERPINE1 | P05121 | Plasminogen activator inhibitor 1 | chr7 | GO:0050829 | Not Cancer Driver | No | 78 | 0.194 | 7 | 2 | 0.286 | 0 |
| SLC11A1 | SLC11A1 | P49279 | Natural resistance-associated macrophage protein 1 | chr2 | GO:0050829 | Not Cancer Driver | No | 79 | 0.144 | 47 | 5 | 0.106 | 0 |
| SSC5D | SSC5D | A1L4H1 | Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D | chr19 | GO:0050829 | Not Cancer Driver | No | 81 | 0.051 | 1194 | 70 | 0.059 | 0 |
| TLR4_ENST00000355622 | TLR4 | O00206 | Toll-like receptor 4 | chr9 | GO:0050829 | Not Cancer Driver | No | 292 | 0.348 | 0 | 0 | 0.0 | 0 |
| TLR9 | TLR9 | Q9NR96 | Toll-like receptor 9 | chr3 | GO:0050829 | Not Cancer Driver | No | 141 | 0.137 | 35 | 3 | 0.086 | 0 |
| TNFRSF14 | TNFRSF14 | Q92956 | Tumor necrosis factor receptor superfamily member 14 | chr1 | GO:0050829 | Census, Compendium | Yes | 33 | 0.117 | 54 | 8 | 0.148 | 0 |
| TREM2 | TREM2 | Q9NZC2 | Triggering receptor expressed on myeloid cells 2 | chr6 | GO:0050829 | Not Cancer Driver | No | 43 | 0.187 | 27 | 2 | 0.074 | 1 |