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Total number of protein in "GO:0050776" GO term:  643

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
A2M A2M P01023 Alpha-2-macroglobulin chr12 GO:0050776 Not Cancer Driver No 260 0.176 144 22 0.153 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0050776 Census, Compendium Yes 139 0.123 604 73 0.121 2
AC136428.1 IGHV3OR16-17 S4R3C0 Immunoglobulin heavy variable 3/OR16-17 (non-functional) (Fragment) chr16 GO:0050776 Not Cancer Driver No 42 0.362 0 0 0.0 0
ACOD1 ACOD1 A6NK06 Cis-aconitate decarboxylase chr13 GO:0050776 Not Cancer Driver No 5 0.01 36 0 0.0 0
ADA ADA P00813 Adenosine deaminase chr20 GO:0050776 Not Cancer Driver No 50 0.138 44 9 0.205 27
ADAR ADAR P55265 Double-stranded RNA-specific adenosine deaminase chr1 GO:0050776 Not Cancer Driver No 149 0.122 675 83 0.123 12
ADGRE2 ADGRE2 Q9UHX3 Adhesion G protein-coupled receptor E2 chr19 GO:0050776 Not Cancer Driver No 134 0.163 104 22 0.212 1
ADORA2B ADORA2B P29275 Adenosine receptor A2b chr17 GO:0050776 Not Cancer Driver No 23 0.069 0 0 0.0 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0050776 Not Cancer Driver No 31 0.077 297 21 0.071 0
AHR AHR P35869 Aryl hydrocarbon receptor chr7 GO:0050776 Not Cancer Driver No 129 0.152 351 75 0.214 0
ALOX15_ENST00000293761 ALOX15 P16050 Polyunsaturated fatty acid lipoxygenase ALOX15 chr17 GO:0050776 Not Cancer Driver No 84 0.127 46 7 0.152 0
ALPK1_ENST00000177648 ALPK1 Q96QP1 Alpha-protein kinase 1 chr4 GO:0050776 Not Cancer Driver No 183 0.147 480 64 0.133 1
AMBP AMBP P02760 Protein AMBP chr9 GO:0050776 Not Cancer Driver No 57 0.162 61 15 0.246 0
ANKRD17 ANKRD17 O75179 Ankyrin repeat domain-containing protein 17 chr4 GO:0050776 Not Cancer Driver No 312 0.12 1790 221 0.123 9
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0050776 Not Cancer Driver No 59 0.171 61 12 0.197 0
AP1G1_ENST00000569748 AP1G1 O43747 AP-1 complex subunit gamma-1 chr16 GO:0050776 Not Cancer Driver No 111 0.135 144 22 0.153 0
APCS APCS P02743 Serum amyloid P-component chr1 GO:0050776 Not Cancer Driver No 73 0.327 0 0 0.0 0
APLF APLF Q8IW19 Aprataxin and PNK-like factor chr2 GO:0050776 Not Cancer Driver No 64 0.125 407 57 0.14 0
APPL1 APPL1 Q9UKG1 DCC-interacting protein 13-alpha chr3 GO:0050776 Not Cancer Driver No 67 0.094 292 31 0.106 1
APPL2_ENST00000258530 APPL2 Q8NEU8 DCC-interacting protein 13-beta chr12 GO:0050776 Not Cancer Driver No 70 0.105 149 14 0.094 0
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:0050776 Not Cancer Driver No 41 0.127 83 12 0.145 9
ARG2 ARG2 P78540 Arginase-2, mitochondrial chr14 GO:0050776 Not Cancer Driver No 25 0.071 58 3 0.052 0
ARID5A ARID5A Q03989 AT-rich interactive domain-containing protein 5A chr2 GO:0050776 Not Cancer Driver No 64 0.108 373 42 0.113 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0050776 Not Cancer Driver No 46 0.112 122 22 0.18 0
ATAD5 ATAD5 Q96QE3 ATPase family AAA domain-containing protein 5 chr17 GO:0050776 Not Cancer Driver No 200 0.108 1075 112 0.104 0
AZGP1 AZGP1 P25311 Zinc-alpha-2-glycoprotein chr7 GO:0050776 Not Cancer Driver No 59 0.198 41 10 0.244 0
B2M B2M P61769 Beta-2-microglobulin chr15 GO:0050776 Census, Compendium Yes 34 0.286 5 1 0.2 2
BANF1_ENST00000445560 BANF1 O75531 Barrier-to-autointegration factor chr11 GO:0050776 Not Cancer Driver No 10 0.112 11 2 0.182 1
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0050776 Census Yes 30 0.156 39 2 0.051 0
BCL10 BCL10 O95999 B-cell lymphoma/leukemia 10 chr1 GO:0050776 Census, Compendium Yes 36 0.155 151 25 0.166 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0050776 Census, Compendium Yes 134 0.19 328 67 0.204 0
BCR BCR P11274 Breakpoint cluster region protein chr22 GO:0050776 Census, Compendium Yes 146 0.115 603 69 0.114 0
BIRC2 BIRC2 Q13490 Baculoviral IAP repeat-containing protein 2 chr11 GO:0050776 Not Cancer Driver No 69 0.112 83 9 0.108 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 GO:0050776 Census, Compendium Yes 77 0.127 98 16 0.163 0
BLK BLK P51451 Tyrosine-protein kinase Blk chr8 GO:0050776 Not Cancer Driver No 94 0.186 75 21 0.28 0
BPIFB1 BPIFB1 Q8TDL5 BPI fold-containing family B member 1 chr20 GO:0050776 Not Cancer Driver No 93 0.192 7 0 0.0 0
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX GO:0050776 Census, Compendium Yes 147 0.223 114 27 0.237 110
BTN2A2 BTN2A2 Q8WVV5 Butyrophilin subfamily 2 member A2 chr6 GO:0050776 Not Cancer Driver No 92 0.176 24 2 0.083 0
C12orf4 C12orf4 Q9NQ89 Protein C12orf4 chr12 GO:0050776 Not Cancer Driver No 70 0.127 111 8 0.072 1
C17orf99 C17orf99 Q6UX52 Protein IL-40 chr17 GO:0050776 Not Cancer Driver No 16 0.06 84 3 0.036 0
C1QA C1QA P02745 Complement C1q subcomponent subunit A chr1 GO:0050776 Not Cancer Driver No 41 0.167 124 16 0.129 0
C1QB C1QB P02746 Complement C1q subcomponent subunit B chr1 GO:0050776 Not Cancer Driver No 46 0.182 133 31 0.233 1
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 GO:0050776 Not Cancer Driver No 14 0.05 103 6 0.058 2
C1QC C1QC P02747 Complement C1q subcomponent subunit C chr1 GO:0050776 Not Cancer Driver No 46 0.188 134 26 0.194 1
C1R C1R P00736 Complement C1r subcomponent chr12 GO:0050776 Not Cancer Driver No 88 0.125 51 6 0.118 6
C1RL C1RL Q9NZP8 Complement C1r subcomponent-like protein chr12 GO:0050776 Not Cancer Driver No 60 0.123 146 22 0.151 0
C1S C1S P09871 Complement C1s subcomponent chr12 GO:0050776 Not Cancer Driver No 128 0.186 97 21 0.216 1
C2 C2 P06681 Complement C2 chr6 GO:0050776 Not Cancer Driver No 120 0.16 120 17 0.142 3
C3 C3 P01024 Complement C3 chr19 GO:0050776 Not Cancer Driver No 337 0.203 287 50 0.174 12
C3AR1 C3AR1 Q16581 C3a anaphylatoxin chemotactic receptor chr12 GO:0050776 Not Cancer Driver No 88 0.183 72 16 0.222 0
C4A C4A P0C0L4 Complement C4-A chr6 GO:0050776 Not Cancer Driver No 43 0.025 309 6 0.019 0
C4BPA C4BPA P04003 C4b-binding protein alpha chain chr1 GO:0050776 Not Cancer Driver No 109 0.183 40 10 0.25 0
C4BPB C4BPB P20851 C4b-binding protein beta chain chr1 GO:0050776 Not Cancer Driver No 40 0.159 0 0 0.0 0
C5 C5 P01031 Complement C5 chr9 GO:0050776 Not Cancer Driver No 192 0.115 84 9 0.107 0
C5AR1 C5AR1 P21730 C5a anaphylatoxin chemotactic receptor 1 chr19 GO:0050776 Not Cancer Driver No 71 0.203 0 0 0.0 0
C5AR2_ENST00000600626 C5AR2 Q9P296 C5a anaphylatoxin chemotactic receptor 2 chr19 GO:0050776 Not Cancer Driver No 60 0.178 11 3 0.273 0
C6 C6 P13671 Complement component C6 chr5 GO:0050776 Not Cancer Driver No 346 0.37 121 47 0.388 0
C7 C7 P10643 Complement component C7 chr5 GO:0050776 Not Cancer Driver No 291 0.345 89 37 0.416 5
C8A C8A P07357 Complement component C8 alpha chain chr1 GO:0050776 Not Cancer Driver No 176 0.301 25 9 0.36 0
C8B C8B P07358 Complement component C8 beta chain chr1 GO:0050776 Not Cancer Driver No 186 0.315 29 11 0.379 0
C8G C8G P07360 Complement component C8 gamma chain chr9 GO:0050776 Not Cancer Driver No 10 0.05 26 2 0.077 0
C9 C9 P02748 Complement component C9 chr5 GO:0050776 Not Cancer Driver No 156 0.279 40 8 0.2 2
CACTIN CACTIN Q8WUQ7 Cactin chr19 GO:0050776 Not Cancer Driver No 94 0.124 503 54 0.107 0
CADM1_ENST00000452722 CADM1 Q9BY67 Cell adhesion molecule 1 chr11 GO:0050776 Not Cancer Driver No 106 0.24 103 28 0.272 0
CARD11 CARD11 Q9BXL7 Caspase recruitment domain-containing protein 11 chr7 GO:0050776 Census, Compendium Yes 303 0.263 530 140 0.264 5
CARD9 CARD9 Q9H257 Caspase recruitment domain-containing protein 9 chr9 GO:0050776 Not Cancer Driver No 72 0.134 225 35 0.156 11
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0050776 Not Cancer Driver No 30 0.169 2 0 0.0 0
CBLB CBLB Q13191 E3 ubiquitin-protein ligase CBL-B chr3 GO:0050776 Census Yes 160 0.163 562 104 0.185 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0050776 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCR2_ENST00000400888 CCR2 P41597 C-C chemokine receptor type 2 chr3 GO:0050776 Not Cancer Driver No 81 0.217 23 1 0.043 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0050776 Census, Compendium Yes 50 0.132 0 0 0.0 0
CD160_ENST00000369288 CD160 O95971 CD160 antigen chr1 GO:0050776 Not Cancer Driver No 20 0.11 2 0 0.0 0
CD177 CD177 Q8N6Q3 CD177 antigen chr19 GO:0050776 Not Cancer Driver No 71 0.162 79 26 0.329 0
CD19_ENST00000324662 CD19 P15391 B-lymphocyte antigen CD19 chr16 GO:0050776 Not Cancer Driver No 80 0.144 312 46 0.147 0
CD1A CD1A P06126 T-cell surface glycoprotein CD1a chr1 GO:0050776 Not Cancer Driver No 105 0.321 18 6 0.333 0
CD1B CD1B P29016 T-cell surface glycoprotein CD1b chr1 GO:0050776 Not Cancer Driver No 97 0.291 7 0 0.0 0
CD1C CD1C P29017 T-cell surface glycoprotein CD1c chr1 GO:0050776 Not Cancer Driver No 127 0.381 1 0 0.0 0
CD1D CD1D P15813 Antigen-presenting glycoprotein CD1d chr1 GO:0050776 Not Cancer Driver No 93 0.278 19 7 0.368 0
CD1E CD1E P15812 T-cell surface glycoprotein CD1e, membrane-associated chr1 GO:0050776 Not Cancer Driver No 158 0.407 21 11 0.524 0
CD200R1_ENST00000471858 CD200R1 Q8TD46 Cell surface glycoprotein CD200 receptor 1 chr3 GO:0050776 Not Cancer Driver No 87 0.268 56 12 0.214 0
CD200_ENST00000315711 CD200 P41217 OX-2 membrane glycoprotein chr3 GO:0050776 Not Cancer Driver No 37 0.133 14 0 0.0 0
CD22 CD22 P20273 B-cell receptor CD22 chr19 GO:0050776 Not Cancer Driver No 173 0.204 290 66 0.228 0
CD226_ENST00000582621 CD226 Q15762 CD226 antigen chr18 GO:0050776 Not Cancer Driver No 79 0.235 47 11 0.234 0
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 GO:0050776 Census Yes 29 0.1 54 9 0.167 0
CD276 CD276 Q5ZPR3 CD276 antigen chr15 GO:0050776 Not Cancer Driver No 62 0.116 139 10 0.072 0
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:0050776 Census Yes 42 0.191 18 10 0.556 0
CD300A CD300A Q9UGN4 CMRF35-like molecule 8 chr17 GO:0050776 Not Cancer Driver No 53 0.177 70 10 0.143 0
CD300LF_ENST00000326165 CD300LF Q8TDQ1 CMRF35-like molecule 1 chr17 GO:0050776 Not Cancer Driver No 36 0.124 88 11 0.125 0
CD33 CD33 P20138 Myeloid cell surface antigen CD33 chr19 GO:0050776 Not Cancer Driver No 119 0.327 177 50 0.282 0
CD36_ENST00000309881 CD36 P16671 Platelet glycoprotein 4 chr7 GO:0050776 Not Cancer Driver No 75 0.159 12 3 0.25 3
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 GO:0050776 Not Cancer Driver No 69 0.151 56 11 0.196 0
CD40 CD40 P25942 Tumor necrosis factor receptor superfamily member 5 chr20 GO:0050776 Not Cancer Driver No 39 0.141 56 6 0.107 2
CD46_ENST00000358170 CD46 P15529 Membrane cofactor protein chr1 GO:0050776 Not Cancer Driver No 53 0.135 52 4 0.077 5
CD47 CD47 Q08722 Leukocyte surface antigen CD47 chr3 GO:0050776 Not Cancer Driver No 37 0.115 0 0 0.0 0
CD55_ENST00000367064 CD55 P08174 Complement decay-accelerating factor chr1 GO:0050776 Not Cancer Driver No 45 0.118 128 13 0.102 1
CD59_ENST00000395850 CD59 P13987 CD59 glycoprotein chr11 GO:0050776 Not Cancer Driver No 18 0.141 0 0 0.0 1
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0050776 Census Yes 31 0.105 185 20 0.108 0
CD80_ENST00000478182 CD80 P33681 T-lymphocyte activation antigen CD80 chr3 GO:0050776 Not Cancer Driver No 50 0.174 26 5 0.192 0
CD81 CD81 P60033 CD81 antigen chr11 GO:0050776 Not Cancer Driver No 28 0.119 0 0 0.0 0
CD84 CD84 Q9UIB8 SLAM family member 5 chr1 GO:0050776 Not Cancer Driver No 82 0.238 52 11 0.212 0
CD86 CD86 P42081 T-lymphocyte activation antigen CD86 chr3 GO:0050776 Not Cancer Driver No 90 0.274 56 18 0.321 0
CD8B2 CD8B2 A6NJW9 T-cell surface glycoprotein CD8 beta-2 chain chr2 GO:0050776 Not Cancer Driver No 1 0.005 10 0 0.0 0
CD96 CD96 P40200 T-cell surface protein tactile chr3 GO:0050776 Not Cancer Driver No 132 0.226 165 34 0.206 1
CDC37 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 GO:0050776 Not Cancer Driver No 52 0.138 214 31 0.145 0
CEACAM1 CEACAM1 P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 chr19 GO:0050776 Not Cancer Driver No 64 0.122 241 25 0.104 0
CFB CFB P00751 Complement factor B chr6 GO:0050776 Not Cancer Driver No 75 0.098 112 20 0.179 7
CFD_ENST00000327726 CFD P00746 Complement factor D chr19 GO:0050776 Not Cancer Driver No 6 0.024 69 3 0.043 2
CFH CFH P08603 Complement factor H chr1 GO:0050776 Not Cancer Driver No 355 0.288 89 28 0.315 42
CFHR5 CFHR5 Q9BXR6 Complement factor H-related protein 5 chr1 GO:0050776 Not Cancer Driver No 162 0.285 40 9 0.225 0
CFI_ENST00000394634 CFI P05156 Complement factor I chr4 GO:0050776 Not Cancer Driver No 97 0.166 4 0 0.0 13
CFP CFP P27918 Properdin chrX GO:0050776 Not Cancer Driver No 60 0.128 48 7 0.146 6
CLC CLC Q05315 Galectin-10 chr19 GO:0050776 Not Cancer Driver No 29 0.204 0 0 0.0 0
CLCF1 CLCF1 Q9UBD9 Cardiotrophin-like cytokine factor 1 chr11 GO:0050776 Not Cancer Driver No 22 0.098 42 4 0.095 1
CLEC12B CLEC12B Q2HXU8 C-type lectin domain family 12 member B chr12 GO:0050776 Not Cancer Driver No 34 0.123 57 8 0.14 0
CLEC4D CLEC4D Q8WXI8 C-type lectin domain family 4 member D chr12 GO:0050776 Not Cancer Driver No 59 0.274 17 3 0.176 0
CLEC4E CLEC4E Q9ULY5 C-type lectin domain family 4 member E chr12 GO:0050776 Not Cancer Driver No 56 0.256 5 2 0.4 0
CLEC4G CLEC4G Q6UXB4 C-type lectin domain family 4 member G chr19 GO:0050776 Not Cancer Driver No 40 0.137 35 4 0.114 0
CLEC6A CLEC6A Q6EIG7 C-type lectin domain family 6 member A chr12 GO:0050776 Not Cancer Driver No 41 0.196 7 0 0.0 0
CLEC7A CLEC7A Q9BXN2 C-type lectin domain family 7 member A chr12 GO:0050776 Not Cancer Driver No 43 0.174 46 2 0.043 0
CLNK CLNK Q7Z7G1 Cytokine-dependent hematopoietic cell linker chr4 GO:0050776 Not Cancer Driver No 85 0.199 320 73 0.228 0
CLPB CLPB Q9H078 Caseinolytic peptidase B protein homolog chr11 GO:0050776 Not Cancer Driver No 69 0.098 224 25 0.112 11
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0050776 Not Cancer Driver No 69 0.154 156 27 0.173 0
CMKLR1 CMKLR1 Q99788 Chemerin-like receptor 1 chr12 GO:0050776 Not Cancer Driver No 107 0.287 24 13 0.542 0
CMTM3_ENST00000567572 CMTM3 Q96MX0 CKLF-like MARVEL transmembrane domain-containing protein 3 chr16 GO:0050776 Not Cancer Driver No 16 0.088 39 1 0.026 0
CNOT7 CNOT7 Q9UIV1 CCR4-NOT transcription complex subunit 7 chr8 GO:0050776 Not Cancer Driver No 31 0.109 21 1 0.048 0
CNR1_ENST00000549890 CNR1 P21554 Cannabinoid receptor 1 chr6 GO:0050776 Not Cancer Driver No 129 0.273 9 1 0.111 0
COL3A1 COL3A1 P02461 Collagen alpha-1(III) chain chr2 GO:0050776 Census Yes 402 0.274 1182 337 0.285 103
COLEC10 COLEC10 Q9Y6Z7 Collectin-10 chr8 GO:0050776 Not Cancer Driver No 58 0.209 95 23 0.242 1
COLEC11_ENST00000349077 COLEC11 Q9BWP8 Collectin-11 chr2 GO:0050776 Not Cancer Driver No 72 0.266 158 40 0.253 2
COLEC12 COLEC12 Q5KU26 Collectin-12 chr18 GO:0050776 Not Cancer Driver No 147 0.198 450 90 0.2 0
CR1L CR1L Q2VPA4 Complement component receptor 1-like protein chr1 GO:0050776 Not Cancer Driver No 121 0.213 55 14 0.255 0
CR1_ENST00000367053 CR1 P17927 Complement receptor type 1 chr1 GO:0050776 Compendium Yes 383 0.188 151 42 0.278 0
CR2_ENST00000367058 CR2 P20023 Complement receptor type 2 chr1 GO:0050776 Not Cancer Driver No 273 0.264 85 28 0.329 0
CREBBP CREBBP Q92793 CREB-binding protein chr16 GO:0050776 Census, Compendium Yes 412 0.169 1796 247 0.138 33
CRK CRK P46108 Adapter molecule crk chr17 GO:0050776 Not Cancer Driver No 30 0.099 197 23 0.117 0
CRP CRP P02741 C-reactive protein chr1 GO:0050776 Not Cancer Driver No 59 0.263 0 0 0.0 0
CRTAM CRTAM O95727 Cytotoxic and regulatory T-cell molecule chr11 GO:0050776 Not Cancer Driver No 64 0.163 135 14 0.104 0
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 GO:0050776 Not Cancer Driver No 41 0.091 18 1 0.056 0
CTLA4 CTLA4 P16410 Cytotoxic T-lymphocyte protein 4 chr2 GO:0050776 Not Cancer Driver No 37 0.166 3 0 0.0 1
CXCL13 CXCL13 O43927 C-X-C motif chemokine 13 chr4 GO:0050776 Not Cancer Driver No 11 0.101 0 0 0.0 0
CXorf21 TASL Q9HAI6 TLR adapter interacting with SLC15A4 on the lysosome chrX GO:0050776 Not Cancer Driver No 73 0.243 66 21 0.318 0
CYBA CYBA P13498 Cytochrome b-245 light chain chr16 GO:0050776 Not Cancer Driver No 26 0.133 66 2 0.03 12
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 GO:0050776 Census, Compendium Yes 116 0.121 213 31 0.146 3
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0050776 Not Cancer Driver No 131 0.11 681 68 0.1 0
DCST1 DCST1 Q5T197 E3 ubiquitin-protein ligase DCST1 chr1 GO:0050776 Not Cancer Driver No 108 0.153 51 9 0.176 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:0050776 Census, Compendium Yes 133 0.201 301 47 0.156 18
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 GO:0050776 Not Cancer Driver No 118 0.128 61 10 0.164 2
DDX60 DDX60 Q8IY21 Probable ATP-dependent RNA helicase DDX60 chr4 GO:0050776 Not Cancer Driver No 224 0.131 131 12 0.092 0
DENND1B DENND1B Q6P3S1 DENN domain-containing protein 1B chr1 GO:0050776 Not Cancer Driver No 69 0.089 299 19 0.064 0
DGKZ_ENST00000456247 DGKZ Q13574 Diacylglycerol kinase zeta chr11 GO:0050776 Not Cancer Driver No 87 0.094 410 42 0.102 0
DHX58 DHX58 Q96C10 ATP-dependent RNA helicase DHX58 chr17 GO:0050776 Not Cancer Driver No 62 0.091 84 8 0.095 0
DNASE2 DNASE2 O00115 Deoxyribonuclease-2-alpha chr19 GO:0050776 Not Cancer Driver No 46 0.128 48 7 0.146 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0050776 Not Cancer Driver No 127 0.287 124 45 0.363 0
DUSP10 DUSP10 Q9Y6W6 Dual specificity protein phosphatase 10 chr1 GO:0050776 Not Cancer Driver No 81 0.168 135 24 0.178 0
DUSP22_ENST00000344450 DUSP22 Q9NRW4 Dual specificity protein phosphatase 22 chr6 GO:0050776 Not Cancer Driver No 84 0.457 0 0 0.0 0
DUSP3 DUSP3 P51452 Dual specificity protein phosphatase 3 chr17 GO:0050776 Not Cancer Driver No 21 0.114 4 1 0.25 0
ECM1_ENST00000369047 ECM1 Q16610 Extracellular matrix protein 1 chr1 GO:0050776 Not Cancer Driver No 91 0.169 219 28 0.128 1
ELF1 ELF1 P32519 ETS-related transcription factor Elf-1 chr13 GO:0050776 Not Cancer Driver No 78 0.126 469 62 0.132 0
ENPP3_ENST00000357639 ENPP3 O14638 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 chr6 GO:0050776 Not Cancer Driver No 146 0.167 57 12 0.211 0
ENTPD7 ENTPD7 Q9NQZ7 Ectonucleoside triphosphate diphosphohydrolase 7 chr10 GO:0050776 Not Cancer Driver No 90 0.149 26 3 0.115 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0050776 Census, Compendium Yes 334 0.138 1790 196 0.109 1
EPG5 EPG5 Q9HCE0 Ectopic P granules protein 5 homolog chr18 GO:0050776 Not Cancer Driver No 305 0.118 347 46 0.133 2
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0050776 Not Cancer Driver No 186 0.176 119 17 0.143 7
ERBIN_ENST00000284037 ERBIN Q96RT1 Erbin chr5 GO:0050776 Not Cancer Driver No 167 0.118 967 118 0.122 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 GO:0050776 Census, Compendium Yes 121 0.203 195 27 0.138 2
EXOSC3 EXOSC3 Q9NQT5 Exosome complex component RRP40 chr9 GO:0050776 Not Cancer Driver No 18 0.065 54 2 0.037 4
EXOSC6 EXOSC6 Q5RKV6 Exosome complex component MTR3 chr16 GO:0050776 Not Cancer Driver No 3 0.011 102 0 0.0 0
EZR EZR P15311 Ezrin chr6 GO:0050776 Census Yes 66 0.113 295 35 0.119 0
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0050776 Not Cancer Driver No 55 0.139 7 2 0.286 0
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0050776 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAM3A_ENST00000447601 FAM3A P98173 Protein FAM3A chrX GO:0050776 Not Cancer Driver No 27 0.117 48 9 0.188 0
FAM49B_ENST00000519540 CYRIB Q9NUQ9 CYFIP-related Rac1 interactor B chr8 GO:0050776 Not Cancer Driver No 53 0.164 78 11 0.141 0
FBXO38_ENST00000340253 FBXO38 Q6PIJ6 F-box only protein 38 chr5 GO:0050776 Not Cancer Driver No 133 0.112 440 48 0.109 1
FCER1A FCER1A P12319 High affinity immunoglobulin epsilon receptor subunit alpha chr1 GO:0050776 Not Cancer Driver No 83 0.323 13 4 0.308 0
FCER1G FCER1G P30273 High affinity immunoglobulin epsilon receptor subunit gamma chr1 GO:0050776 Not Cancer Driver No 10 0.116 13 2 0.154 0
FCER2 FCER2 P06734 Low affinity immunoglobulin epsilon Fc receptor chr19 GO:0050776 Not Cancer Driver No 41 0.128 130 22 0.169 0
FCGR1A FCGR1A P12314 High affinity immunoglobulin gamma Fc receptor I chr1 GO:0050776 Not Cancer Driver No 62 0.166 37 5 0.135 0
FCGR1B FCGR1BP Q92637 Putative high affinity immunoglobulin gamma Fc receptor IB chr1 GO:0050776 Not Cancer Driver No 31 0.111 37 6 0.162 0
FCGR2A FCGR2A P12318 Low affinity immunoglobulin gamma Fc region receptor II-a chr1 GO:0050776 Not Cancer Driver No 64 0.202 133 28 0.211 0
FCGR2B FCGR2B P31994 Low affinity immunoglobulin gamma Fc region receptor II-b chr1 GO:0050776 Census Yes 51 0.165 99 30 0.303 0
FCGR2C FCGR2C P31995 Low affinity immunoglobulin gamma Fc region receptor II-c chr1 GO:0050776 Not Cancer Driver No 40 0.124 121 24 0.198 0
FCGR3A_ENST00000443193 FCGR3A P08637 Low affinity immunoglobulin gamma Fc region receptor III-A chr1 GO:0050776 Not Cancer Driver No 69 0.272 0 0 0.0 1
FCGR3B_ENST00000367964 FCGR3B O75015 Low affinity immunoglobulin gamma Fc region receptor III-B chr1 GO:0050776 Not Cancer Driver No 58 0.249 0 0 0.0 0
FCN1 FCN1 O00602 Ficolin-1 chr9 GO:0050776 Not Cancer Driver No 107 0.328 88 15 0.17 0
FCN2 FCN2 Q15485 Ficolin-2 chr9 GO:0050776 Not Cancer Driver No 73 0.233 80 19 0.237 0
FCN3 FCN3 O75636 Ficolin-3 chr1 GO:0050776 Not Cancer Driver No 46 0.154 65 19 0.292 0
FCRL3_ENST00000368184 FCRL3 Q96P31 Fc receptor-like protein 3 chr1 GO:0050776 Not Cancer Driver No 193 0.263 217 44 0.203 0
FCRLB FCRLB Q6BAA4 Fc receptor-like B chr1 GO:0050776 Not Cancer Driver No 51 0.12 147 14 0.095 0
FER FER P16591 Tyrosine-protein kinase Fer chr5 GO:0050776 Not Cancer Driver No 114 0.139 145 21 0.145 0
FES FES P07332 Tyrosine-protein kinase Fes/Fps chr15 GO:0050776 Census Yes 103 0.125 245 34 0.139 0
FFAR2 FFAR2 O15552 Free fatty acid receptor 2 chr19 GO:0050776 Not Cancer Driver No 49 0.148 32 7 0.219 0
FGL1_ENST00000381840 FGL1 Q08830 Fibrinogen-like protein 1 chr8 GO:0050776 Not Cancer Driver No 42 0.135 10 2 0.2 0
FGL2 FGL2 Q14314 Fibroleukin chr7 GO:0050776 Not Cancer Driver No 71 0.162 70 12 0.171 0
FGR_ENST00000374004 FGR P09769 Tyrosine-protein kinase Fgr chr1 GO:0050776 Not Cancer Driver No 85 0.161 52 8 0.154 0
FKBP1A FKBP1A P62942 Peptidyl-prolyl cis-trans isomerase FKBP1A chr20 GO:0050776 Not Cancer Driver No 15 0.139 39 7 0.179 0
FLOT1 FLOT1 O75955 Flotillin-1 chr6 GO:0050776 Not Cancer Driver No 43 0.101 122 15 0.123 0
FLOT2 FLOT2 Q14254 Flotillin-2 chr17 GO:0050776 Not Cancer Driver No 56 0.131 20 3 0.15 0
FOXF1 FOXF1 Q12946 Forkhead box protein F1 chr16 GO:0050776 Not Cancer Driver No 56 0.148 194 20 0.103 20
FOXJ1 FOXJ1 Q92949 Forkhead box protein J1 chr17 GO:0050776 Not Cancer Driver No 25 0.059 279 18 0.065 0
FOXP1_ENST00000318789 FOXP1 Q9H334 Forkhead box protein P1 chr3 GO:0050776 Census, Compendium Yes 109 0.161 448 71 0.158 3
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0050776 Not Cancer Driver No 38 0.088 186 16 0.086 10
FPR1_ENST00000304748 FPR1 P21462 fMet-Leu-Phe receptor chr19 GO:0050776 Not Cancer Driver No 99 0.283 18 3 0.167 0
FPR2 FPR2 P25090 N-formyl peptide receptor 2 chr19 GO:0050776 Not Cancer Driver No 96 0.274 26 5 0.192 0
FPR3 FPR3 P25089 N-formyl peptide receptor 3 chr19 GO:0050776 Not Cancer Driver No 82 0.232 28 2 0.071 0
FURIN_ENST00000610579 FURIN P09958 Furin chr15 GO:0050776 Not Cancer Driver No 93 0.117 283 35 0.124 0
FUT7 FUT7 Q11130 Alpha-(1,3)-fucosyltransferase 7 chr9 GO:0050776 Not Cancer Driver No 28 0.082 25 3 0.12 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0050776 Not Cancer Driver No 92 0.171 70 13 0.186 0
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:0050776 Not Cancer Driver No 45 0.077 58 4 0.069 0
GAB2 GAB2 Q9UQC2 GRB2-associated-binding protein 2 chr11 GO:0050776 Not Cancer Driver No 85 0.126 537 73 0.136 0
GATA1 GATA1 P15976 Erythroid transcription factor chrX GO:0050776 Census, Compendium Yes 68 0.165 242 41 0.169 5
GATA2_ENST00000487848 GATA2 P23769 Endothelial transcription factor GATA-2 chr3 GO:0050776 Census, Compendium Yes 72 0.15 370 49 0.132 6
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0050776 Census, Compendium Yes 111 0.251 364 87 0.239 2
GATA6 GATA6 Q92908 Transcription factor GATA-6 chr18 GO:0050776 Not Cancer Driver No 57 0.096 476 51 0.107 10
GBP1 GBP1 P32455 Guanylate-binding protein 1 chr1 GO:0050776 Not Cancer Driver No 92 0.155 166 27 0.163 0
GCSAML_ENST00000366488 GCSAML Q5JQS6 Germinal center-associated signaling and motility-like protein chr1 GO:0050776 Not Cancer Driver No 66 0.489 130 59 0.454 0
GCSAM_ENST00000308910 GCSAM Q8N6F7 Germinal center-associated signaling and motility protein chr3 GO:0050776 Not Cancer Driver No 31 0.174 136 22 0.162 0
GFER GFER P55789 FAD-linked sulfhydryl oxidase ALR chr16 GO:0050776 Not Cancer Driver No 10 0.049 97 4 0.041 1
GFI1 GFI1 Q99684 Zinc finger protein Gfi-1 chr1 GO:0050776 Not Cancer Driver No 57 0.135 199 29 0.146 2
GPATCH3 GPATCH3 Q96I76 G patch domain-containing protein 3 chr1 GO:0050776 Not Cancer Driver No 64 0.122 354 48 0.136 0
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0050776 Not Cancer Driver No 153 0.182 36 9 0.25 0
GPR108 GPR108 Q9NPR9 Protein GPR108 chr19 GO:0050776 Not Cancer Driver No 64 0.118 56 12 0.214 0
GPR32 GPR32 O75388 Probable G-protein coupled receptor 32 chr19 GO:0050776 Not Cancer Driver No 85 0.239 18 6 0.333 0
GPS2 GPS2 Q13227 G protein pathway suppressor 2 chr17 GO:0050776 Not Cancer Driver No 29 0.089 319 26 0.082 0
GPX1_ENST00000620890 GPX1 P07203 Glutathione peroxidase 1 chr3 GO:0050776 Not Cancer Driver No 38 0.187 12 1 0.083 0
GRAMD4_ENST00000361034 GRAMD4 Q6IC98 GRAM domain-containing protein 4 chr22 GO:0050776 Not Cancer Driver No 79 0.137 165 27 0.164 0
GRN GRN P28799 Progranulin chr17 GO:0050776 Not Cancer Driver No 76 0.128 29 6 0.207 1
HAVCR2 HAVCR2 Q8TDQ0 Hepatitis A virus cellular receptor 2 chr5 GO:0050776 Not Cancer Driver No 69 0.229 17 2 0.118 3
HCK_ENST00000534862 HCK P08631 Tyrosine-protein kinase HCK chr20 GO:0050776 Not Cancer Driver No 112 0.213 124 25 0.202 0
HCST HCST Q9UBK5 Hematopoietic cell signal transducer chr19 GO:0050776 Not Cancer Driver No 6 0.065 12 0 0.0 0
HFE HFE Q30201 Hereditary hemochromatosis protein chr6 GO:0050776 Not Cancer Driver No 55 0.158 27 2 0.074 11
HLA-A_ENST00000376809 HLA-A P04439 HLA class I histocompatibility antigen, A alpha chain chr6 GO:0050776 Census, Compendium Yes 128 0.351 125 60 0.48 0
HLA-B HLA-B P01889 HLA class I histocompatibility antigen, B alpha chain chr6 GO:0050776 Compendium Yes 78 0.215 169 34 0.201 0
HLA-DMB HLA-DMB P28068 HLA class II histocompatibility antigen, DM beta chain chr6 GO:0050776 Not Cancer Driver No 41 0.156 41 9 0.22 0
HLA-DRA HLA-DRA P01903 HLA class II histocompatibility antigen, DR alpha chain chr6 GO:0050776 Not Cancer Driver No 52 0.205 12 1 0.083 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0050776 Not Cancer Driver No 48 0.18 12 1 0.083 0
HLA-E HLA-E P13747 HLA class I histocompatibility antigen, alpha chain E chr6 GO:0050776 Not Cancer Driver No 63 0.176 138 39 0.283 0
HLA-F_ENST00000376861 HLA-F P30511 HLA class I histocompatibility antigen, alpha chain F chr6 GO:0050776 Not Cancer Driver No 43 0.124 115 22 0.191 0
HLA-G_ENST00000360323 HLA-G P17693 HLA class I histocompatibility antigen, alpha chain G chr6 GO:0050776 Not Cancer Driver No 94 0.278 85 22 0.259 0
HLX HLX Q14774 H2.0-like homeobox protein chr1 GO:0050776 Not Cancer Driver No 107 0.219 412 98 0.238 0
HMCES_ENST00000502878 HMCES Q96FZ2 Abasic site processing protein HMCES chr3 GO:0050776 Not Cancer Driver No 37 0.105 131 16 0.122 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0050776 Not Cancer Driver No 25 0.116 203 20 0.099 0
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0050776 Not Cancer Driver No 46 0.16 81 13 0.16 0
HPX HPX P02790 Hemopexin chr11 GO:0050776 Not Cancer Driver No 60 0.13 53 8 0.151 0
HRG HRG P04196 Histidine-rich glycoprotein chr3 GO:0050776 Not Cancer Driver No 121 0.23 277 75 0.271 2
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0050776 Census, Compendium Yes 100 0.138 254 43 0.169 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0050776 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPA1B HSPA1B P0DMV9 Heat shock 70 kDa protein 1B chr6 GO:0050776 Not Cancer Driver No 15 0.023 200 5 0.025 0
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 GO:0050776 Not Cancer Driver No 61 0.106 82 6 0.073 2
IDO1_ENST00000522495 IDO1 P14902 Indoleamine 2,3-dioxygenase 1 chr8 GO:0050776 Not Cancer Driver No 82 0.203 41 8 0.195 0
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 GO:0050776 Not Cancer Driver No 155 0.197 419 90 0.215 0
IFI35_ENST00000415816 IFI35 P80217 Interferon-induced 35 kDa protein chr17 GO:0050776 Not Cancer Driver No 33 0.115 63 10 0.159 0
IFIH1 IFIH1 Q9BYX4 Interferon-induced helicase C domain-containing protein 1 chr2 GO:0050776 Not Cancer Driver No 109 0.106 287 36 0.125 9
IFNA2 IFNA2 P01563 Interferon alpha-2 chr9 GO:0050776 Not Cancer Driver No 38 0.202 2 0 0.0 0
IFNB1 IFNB1 P01574 Interferon beta chr9 GO:0050776 Not Cancer Driver No 46 0.246 0 0 0.0 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0050776 Not Cancer Driver No 51 0.307 23 6 0.261 0
IFNL1 IFNL1 Q8IU54 Interferon lambda-1 chr19 GO:0050776 Not Cancer Driver No 24 0.12 49 8 0.163 0
IGHD IGHD P01880 Immunoglobulin heavy constant delta chr14 GO:0050776 Not Cancer Driver No 61 0.159 245 40 0.163 0
IGLL1 IGLL1 P15814 Immunoglobulin lambda-like polypeptide 1 chr22 GO:0050776 Not Cancer Driver No 25 0.117 144 18 0.125 1
IGLL5 IGLL5 B9A064 Immunoglobulin lambda-like polypeptide 5 chr22 GO:0050776 Not Cancer Driver No 59 0.276 127 35 0.276 0
IKBKB IKBKB O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta chr8 GO:0050776 Census, Compendium Yes 106 0.14 211 31 0.147 1
IKBKE IKBKE Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon chr1 GO:0050776 Not Cancer Driver No 108 0.151 76 13 0.171 0
IKBKG_ENST00000611071 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX GO:0050776 Not Cancer Driver No 6 0.014 301 6 0.02 22
IL10 IL10 P22301 Interleukin-10 chr1 GO:0050776 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0050776 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL12RB1_ENST00000593993 IL12RB1 P42701 Interleukin-12 receptor subunit beta-1 chr19 GO:0050776 Not Cancer Driver No 108 0.163 207 38 0.184 1
IL13 IL13 P35225 Interleukin-13 chr5 GO:0050776 Not Cancer Driver No 20 0.137 0 0 0.0 0
IL13RA2_ENST00000243213 IL13RA2 Q14627 Interleukin-13 receptor subunit alpha-2 chrX GO:0050776 Not Cancer Driver No 69 0.182 0 0 0.0 0
IL17A IL17A Q16552 Interleukin-17A chr6 GO:0050776 Not Cancer Driver No 52 0.335 56 21 0.375 0
IL17F IL17F Q96PD4 Interleukin-17F chr6 GO:0050776 Not Cancer Driver No 42 0.258 34 11 0.324 1
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0050776 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL18R1_ENST00000233957 IL18R1 Q13478 Interleukin-18 receptor 1 chr2 GO:0050776 Not Cancer Driver No 104 0.192 18 3 0.167 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0050776 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL1R1 IL1R1 P14778 Interleukin-1 receptor type 1 chr2 GO:0050776 Not Cancer Driver No 77 0.135 59 8 0.136 0
IL1RL1 IL1RL1 Q01638 Interleukin-1 receptor-like 1 chr2 GO:0050776 Not Cancer Driver No 119 0.214 24 8 0.333 0
IL2 IL2 P60568 Interleukin-2 chr4 GO:0050776 Census Yes 24 0.157 6 1 0.167 0
IL20RB IL20RB Q6UXL0 Interleukin-20 receptor subunit beta chr3 GO:0050776 Not Cancer Driver No 40 0.129 0 0 0.0 0
IL23A IL23A Q9NPF7 Interleukin-23 subunit alpha chr12 GO:0050776 Not Cancer Driver No 15 0.079 42 3 0.071 0
IL23R IL23R Q5VWK5 Interleukin-23 receptor chr1 GO:0050776 Not Cancer Driver No 70 0.111 117 19 0.162 0
IL27 IL27 Q8NEV9 Interleukin-27 subunit alpha chr16 GO:0050776 Not Cancer Driver No 37 0.152 27 1 0.037 0
IL27RA IL27RA Q6UWB1 Interleukin-27 receptor subunit alpha chr19 GO:0050776 Not Cancer Driver No 91 0.143 167 23 0.138 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:0050776 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL4I1_ENST00000391826 IL4I1 Q96RQ9 L-amino-acid oxidase chr19 GO:0050776 Not Cancer Driver No 65 0.115 136 14 0.103 0
IL4R_ENST00000543915 IL4R P24394 Interleukin-4 receptor subunit alpha chr16 GO:0050776 Not Cancer Driver No 133 0.161 420 64 0.152 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0050776 Not Cancer Driver No 35 0.165 58 7 0.121 0
IL7R IL7R P16871 Interleukin-7 receptor subunit alpha chr5 GO:0050776 Census, Compendium Yes 177 0.386 88 48 0.545 1
INAVA_ENST00000367342 INAVA Q3KP66 Innate immunity activator protein chr1 GO:0050776 Not Cancer Driver No 112 0.169 553 98 0.177 1
INPP5D INPP5D Q92835 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 chr2 GO:0050776 Not Cancer Driver No 176 0.148 578 90 0.156 0
INS INS P01308 Insulin chr11 GO:0050776 Not Cancer Driver No 15 0.136 5 1 0.2 22
IRAK1 IRAK1 P51617 Interleukin-1 receptor-associated kinase 1 chrX GO:0050776 Compendium Yes 71 0.1 337 39 0.116 0
IRAK2 IRAK2 O43187 Interleukin-1 receptor-associated kinase-like 2 chr3 GO:0050776 Not Cancer Driver No 84 0.134 202 32 0.158 0
IRAK3 IRAK3 Q9Y616 Interleukin-1 receptor-associated kinase 3 chr12 GO:0050776 Not Cancer Driver No 103 0.173 79 14 0.177 0
IRAK4_ENST00000551736 IRAK4 Q9NWZ3 Interleukin-1 receptor-associated kinase 4 chr12 GO:0050776 Not Cancer Driver No 68 0.148 116 20 0.172 2
IRF1 IRF1 P10914 Interferon regulatory factor 1 chr5 GO:0050776 Compendium Yes 49 0.151 228 31 0.136 2
IRF3_ENST00000597198 IRF3 Q14653 Interferon regulatory factor 3 chr19 GO:0050776 Not Cancer Driver No 36 0.084 204 21 0.103 1
IRF4 IRF4 Q15306 Interferon regulatory factor 4 chr6 GO:0050776 Census, Compendium Yes 99 0.22 155 45 0.29 0
IRF7_ENST00000397574 IRF7 Q92985 Interferon regulatory factor 7 chr11 GO:0050776 Not Cancer Driver No 43 0.085 253 19 0.075 1
IRGM IRGM A1A4Y4 Immunity-related GTPase family M protein chr5 GO:0050776 Not Cancer Driver No 9 0.05 45 1 0.022 0
ISG15 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 GO:0050776 Not Cancer Driver No 12 0.073 24 2 0.083 0
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 GO:0050776 Not Cancer Driver No 95 0.105 335 42 0.125 0
ITGAM_ENST00000287497 ITGAM P11215 Integrin alpha-M chr16 GO:0050776 Not Cancer Driver No 191 0.166 133 12 0.09 0
ITGB2_ENST00000355153 ITGB2 P05107 Integrin beta-2 chr21 GO:0050776 Not Cancer Driver No 147 0.191 59 9 0.153 15
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 GO:0050776 Census, Compendium Yes 167 0.149 63 10 0.159 7
KARS_ENST00000302445 KARS1 Q15046 Lysine--tRNA ligase chr16 GO:0050776 Not Cancer Driver No 88 0.147 160 15 0.094 12
KCNN4 KCNN4 O15554 Intermediate conductance calcium-activated potassium channel protein 4 chr19 GO:0050776 Not Cancer Driver No 60 0.141 31 6 0.194 3
KIR2DL1 KIR2DL1 P43626 Killer cell immunoglobulin-like receptor 2DL1 chr19 GO:0050776 Not Cancer Driver No 112 0.322 135 44 0.326 0
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0050776 Census, Compendium Yes 226 0.232 83 33 0.398 21
KLK3 KLK3 P07288 Prostate-specific antigen chr19 GO:0050776 Not Cancer Driver No 68 0.261 6 1 0.167 0
KLK5_ENST00000593428 KLK5 Q9Y337 Kallikrein-5 chr19 GO:0050776 Not Cancer Driver No 69 0.235 75 16 0.213 0
KLK7 KLK7 P49862 Kallikrein-7 chr19 GO:0050776 Not Cancer Driver No 43 0.17 38 8 0.211 0
KLRC1 KLRC1 P26715 NKG2-A/NKG2-B type II integral membrane protein chr12 GO:0050776 Not Cancer Driver No 49 0.21 49 10 0.204 0
KLRC2 KLRC2 P26717 NKG2-C type II integral membrane protein chr12 GO:0050776 Not Cancer Driver No 55 0.238 45 17 0.378 0
KLRC3_ENST00000396439 KLRC3 Q07444 NKG2-E type II integral membrane protein chr12 GO:0050776 Not Cancer Driver No 37 0.154 43 4 0.093 0
KLRC4 KLRC4 O43908 NKG2-F type II integral membrane protein chr12 GO:0050776 Not Cancer Driver No 36 0.228 45 7 0.156 0
KLRD1 KLRD1 Q13241 Natural killer cells antigen CD94 chr12 GO:0050776 Not Cancer Driver No 37 0.207 0 0 0.0 0
KLRK1 KLRK1 P26718 NKG2-D type II integral membrane protein chr12 GO:0050776 Not Cancer Driver No 38 0.176 0 0 0.0 0
KMT5B_ENST00000615954 KMT5B Q4FZB7 Histone-lysine N-methyltransferase KMT5B chr11 GO:0050776 Not Cancer Driver No 147 0.166 659 113 0.171 0
KMT5C KMT5C Q86Y97 Histone-lysine N-methyltransferase KMT5C chr19 GO:0050776 Not Cancer Driver No 37 0.08 142 9 0.063 0
KRT1 KRT1 P04264 Keratin, type II cytoskeletal 1 chr12 GO:0050776 Not Cancer Driver No 133 0.207 426 98 0.23 20
LACC1 LACC1 Q8IV20 Purine nucleoside phosphorylase LACC1 chr13 GO:0050776 Not Cancer Driver No 50 0.116 4 0 0.0 1
LAG3 LAG3 P18627 Lymphocyte activation gene 3 protein chr12 GO:0050776 Not Cancer Driver No 47 0.09 208 11 0.053 0
LAMP1 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 GO:0050776 Not Cancer Driver No 47 0.113 93 10 0.108 0
LAPTM5 LAPTM5 Q13571 Lysosomal-associated transmembrane protein 5 chr1 GO:0050776 Not Cancer Driver No 46 0.176 16 6 0.375 0
LBP LBP P18428 Lipopolysaccharide-binding protein chr20 GO:0050776 Not Cancer Driver No 84 0.175 6 0 0.0 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 GO:0050776 Census Yes 86 0.169 94 13 0.138 1
LEP LEP P41159 Leptin chr7 GO:0050776 Not Cancer Driver No 29 0.174 0 0 0.0 2
LGALS3 LGALS3 P17931 Galectin-3 chr14 GO:0050776 Not Cancer Driver No 15 0.06 133 6 0.045 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0050776 Not Cancer Driver No 54 0.152 65 16 0.246 0
LGR4 LGR4 Q9BXB1 Leucine-rich repeat-containing G-protein coupled receptor 4 chr11 GO:0050776 Not Cancer Driver No 108 0.114 16 3 0.188 0
LILRA2 LILRA2 Q8N149 Leukocyte immunoglobulin-like receptor subfamily A member 2 chr19 GO:0050776 Not Cancer Driver No 163 0.337 137 44 0.321 0
LILRA4 LILRA4 P59901 Leukocyte immunoglobulin-like receptor subfamily A member 4 chr19 GO:0050776 Not Cancer Driver No 124 0.248 109 26 0.239 0
LILRB1_ENST00000396331 LILRB1 Q8NHL6 Leukocyte immunoglobulin-like receptor subfamily B member 1 chr19 GO:0050776 Not Cancer Driver No 203 0.312 291 97 0.333 0
LILRB2_ENST00000314446 LILRB2 Q8N423 Leukocyte immunoglobulin-like receptor subfamily B member 2 chr19 GO:0050776 Not Cancer Driver No 148 0.248 235 50 0.213 0
LILRB4 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 GO:0050776 Not Cancer Driver No 162 0.362 277 115 0.415 0
LIMK1 LIMK1 P53667 LIM domain kinase 1 chr7 GO:0050776 Not Cancer Driver No 110 0.17 170 30 0.176 0
LOXL3 LOXL3 P58215 Lysyl oxidase homolog 3 chr2 GO:0050776 Not Cancer Driver No 91 0.121 86 17 0.198 0
LPXN_ENST00000395074 LPXN O60711 Leupaxin chr11 GO:0050776 Not Cancer Driver No 43 0.111 134 16 0.119 0
LRRC14 LRRC14 Q15048 Leucine-rich repeat-containing protein 14 chr8 GO:0050776 Not Cancer Driver No 63 0.128 25 2 0.08 0
LSM14A_ENST00000433627 LSM14A Q8ND56 Protein LSM14 homolog A chr19 GO:0050776 Census Yes 67 0.145 408 63 0.154 0
LTA LTA P01374 Lymphotoxin-alpha chr6 GO:0050776 Not Cancer Driver No 37 0.18 20 5 0.25 0
LTF LTF P02788 Lactotransferrin chr3 GO:0050776 Not Cancer Driver No 131 0.185 21 4 0.19 0
LYAR_ENST00000452476 LYAR Q9NX58 Cell growth-regulating nucleolar protein chr4 GO:0050776 Not Cancer Driver No 50 0.132 249 31 0.124 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0050776 Census Yes 95 0.186 84 12 0.143 0
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 GO:0050776 Not Cancer Driver No 22 0.104 0 0 0.0 1
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:0050776 Census, Compendium Yes 75 0.091 139 12 0.086 1
MAP2K4_ENST00000353533 MAP2K4 P45985 Dual specificity mitogen-activated protein kinase kinase 4 chr17 GO:0050776 Census, Compendium Yes 89 0.223 137 28 0.204 0
MAP2K6 MAP2K6 P52564 Dual specificity mitogen-activated protein kinase kinase 6 chr17 GO:0050776 Not Cancer Driver No 48 0.144 55 11 0.2 0
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0050776 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K1 MAP3K1 Q13233 Mitogen-activated protein kinase kinase kinase 1 chr5 GO:0050776 Census, Compendium Yes 184 0.122 820 62 0.076 3
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0050776 Not Cancer Driver No 104 0.172 333 66 0.198 6
MAPK10_ENST00000515650 MAPK10 P53779 Mitogen-activated protein kinase 10 chr4 GO:0050776 Not Cancer Driver No 88 0.19 107 16 0.15 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0050776 Not Cancer Driver No 39 0.108 25 1 0.04 0
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 GO:0050776 Not Cancer Driver No 64 0.15 94 9 0.096 0
MAPK9 MAPK9 P45984 Mitogen-activated protein kinase 9 chr5 GO:0050776 Not Cancer Driver No 59 0.139 90 8 0.089 0
MASP1_ENST00000337774 MASP1 P48740 Mannan-binding lectin serine protease 1 chr3 GO:0050776 Not Cancer Driver No 142 0.203 72 14 0.194 0
MASP2 MASP2 O00187 Mannan-binding lectin serine protease 2 chr1 GO:0050776 Not Cancer Driver No 99 0.144 58 11 0.19 2
MAVS MAVS Q7Z434 Mitochondrial antiviral-signaling protein chr20 GO:0050776 Not Cancer Driver No 70 0.13 411 58 0.141 0
MBL2 MBL2 P11226 Mannose-binding protein C chr10 GO:0050776 Not Cancer Driver No 63 0.254 122 32 0.262 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0050776 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0050776 Not Cancer Driver No 92 0.195 408 81 0.199 0
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 GO:0050776 Not Cancer Driver No 74 0.128 274 29 0.106 0
MFAP4_ENST00000299610 MFAP4 P55083 Microfibril-associated glycoprotein 4 chr17 GO:0050776 Not Cancer Driver No 35 0.137 0 0 0.0 0
MFHAS1 MFHAS1 Q9Y4C4 Malignant fibrous histiocytoma-amplified sequence 1 chr8 GO:0050776 Not Cancer Driver No 95 0.09 98 9 0.092 0
MKRN2 MKRN2 Q9H000 E3 ubiquitin-protein ligase makorin-2 chr3 GO:0050776 Not Cancer Driver No 45 0.108 145 16 0.11 0
MLH1 MLH1 P40692 DNA mismatch repair protein Mlh1 chr3 GO:0050776 Census Yes 92 0.122 208 22 0.106 85
MMP12 MMP12 P39900 Macrophage metalloelastase chr11 GO:0050776 Not Cancer Driver No 100 0.213 29 5 0.172 0
MR1 MR1 Q95460 Major histocompatibility complex class I-related gene protein chr1 GO:0050776 Not Cancer Driver No 60 0.176 33 7 0.212 0
MS4A2 MS4A2 Q01362 High affinity immunoglobulin epsilon receptor subunit beta chr11 GO:0050776 Not Cancer Driver No 64 0.262 19 8 0.421 0
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:0050776 Census Yes 92 0.099 37 4 0.108 70
MUL1 MUL1 Q969V5 Mitochondrial ubiquitin ligase activator of NFKB 1 chr1 GO:0050776 Not Cancer Driver No 48 0.136 16 2 0.125 0
MYB_ENST00000367814 MYB P10242 Transcriptional activator Myb chr6 GO:0050776 Census Yes 82 0.128 528 69 0.131 0
MYD88_ENST00000396334 MYD88 Q99836 Myeloid differentiation primary response protein MyD88 chr3 GO:0050776 Census, Compendium Yes 37 0.125 47 1 0.021 2
MYO1G MYO1G B0I1T2 Unconventional myosin-Ig chr7 GO:0050776 Not Cancer Driver No 125 0.123 117 12 0.103 0
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 GO:0050776 Not Cancer Driver No 37 0.095 181 12 0.066 1
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:0050776 Not Cancer Driver No 247 0.219 51 10 0.196 4
NCR1 NCR1 O76036 Natural cytotoxicity triggering receptor 1 chr19 GO:0050776 Not Cancer Driver No 81 0.266 27 8 0.296 0
NCR3LG1 NCR3LG1 Q68D85 Natural cytotoxicity triggering receptor 3 ligand 1 chr11 GO:0050776 Not Cancer Driver No 8 0.018 70 3 0.043 0
NDFIP1 NDFIP1 Q9BT67 NEDD4 family-interacting protein 1 chr5 GO:0050776 Not Cancer Driver No 22 0.1 44 4 0.091 0
NECTIN2 NECTIN2 Q92692 Nectin-2 chr19 GO:0050776 Not Cancer Driver No 63 0.117 296 29 0.098 0
NFAM1 NFAM1 Q8NET5 NFAT activation molecule 1 chr22 GO:0050776 Not Cancer Driver No 30 0.111 116 18 0.155 0
NFKBIA NFKBIA P25963 NF-kappa-B inhibitor alpha chr14 GO:0050776 Compendium Yes 37 0.117 102 9 0.088 1
NFKBID NFKBID Q8NI38 NF-kappa-B inhibitor delta chr19 GO:0050776 Not Cancer Driver No 47 0.15 124 20 0.161 0
NFKBIL1 NFKBIL1 Q9UBC1 NF-kappa-B inhibitor-like protein 1 chr6 GO:0050776 Not Cancer Driver No 37 0.097 316 33 0.104 0
NFKBIZ NFKBIZ Q9BYH8 NF-kappa-B inhibitor zeta chr3 GO:0050776 Not Cancer Driver No 96 0.134 443 53 0.12 0
NINJ1 NINJ1 Q92982 Ninjurin-1 chr9 GO:0050776 Not Cancer Driver No 17 0.112 29 0 0.0 0
NLRC3 NLRC3 Q7RTR2 NLR family CARD domain-containing protein 3 chr16 GO:0050776 Not Cancer Driver No 176 0.165 147 33 0.224 0
NLRC5_ENST00000436936 NLRC5 Q86WI3 Protein NLRC5 chr16 GO:0050776 Not Cancer Driver No 262 0.14 114 19 0.167 0
NLRP10 NLRP10 Q86W26 NACHT, LRR and PYD domains-containing protein 10 chr11 GO:0050776 Not Cancer Driver No 201 0.307 96 34 0.354 0
NLRP3_ENST00000391828 NLRP3 Q96P20 NACHT, LRR and PYD domains-containing protein 3 chr1 GO:0050776 Not Cancer Driver No 339 0.327 64 33 0.516 37
NLRP6 NLRP6 P59044 NACHT, LRR and PYD domains-containing protein 6 chr11 GO:0050776 Not Cancer Driver No 106 0.119 203 28 0.138 0
NLRX1_ENST00000409265 NLRX1 Q86UT6 NLR family member X1 chr11 GO:0050776 Not Cancer Driver No 158 0.162 94 13 0.138 0
NMI NMI Q13287 N-myc-interactor chr2 GO:0050776 Not Cancer Driver No 34 0.111 104 12 0.115 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0050776 Not Cancer Driver No 169 0.163 40 4 0.1 15
NOP53 NOP53 Q9NZM5 Ribosome biogenesis protein NOP53 chr19 GO:0050776 Not Cancer Driver No 59 0.123 391 41 0.105 0
NPLOC4 NPLOC4 Q8TAT6 Nuclear protein localization protein 4 homolog chr17 GO:0050776 Not Cancer Driver No 78 0.128 47 8 0.17 0
NPY5R_ENST00000506953 NPY5R Q15761 Neuropeptide Y receptor type 5 chr4 GO:0050776 Not Cancer Driver No 144 0.324 44 16 0.364 0
NPY_ENST00000405982 NPY P01303 Pro-neuropeptide Y chr7 GO:0050776 Not Cancer Driver No 29 0.299 43 19 0.442 0
NR1D1 NR1D1 P20393 Nuclear receptor subfamily 1 group D member 1 chr17 GO:0050776 Not Cancer Driver No 81 0.132 348 49 0.141 0
NR1H2_ENST00000593926 NR1H2 P55055 Oxysterols receptor LXR-beta chr19 GO:0050776 Not Cancer Driver No 56 0.122 179 30 0.168 0
NR1H3_ENST00000467728 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 GO:0050776 Not Cancer Driver No 56 0.125 146 13 0.089 0
NR1H4 NR1H4 Q96RI1 Bile acid receptor chr12 GO:0050776 Not Cancer Driver No 111 0.228 78 18 0.231 0
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:0050776 Census Yes 83 0.133 298 37 0.124 0
NSD2_ENST00000382892 NSD2 O96028 Histone-lysine N-methyltransferase NSD2 chr4 GO:0050776 Census, Compendium Yes 191 0.14 552 76 0.138 0
OAS1_ENST00000202917 OAS1 P00973 2'-5'-oligoadenylate synthase 1 chr12 GO:0050776 Not Cancer Driver No 67 0.168 71 12 0.169 0
OAS3 OAS3 Q9Y6K5 2'-5'-oligoadenylate synthase 3 chr12 GO:0050776 Not Cancer Driver No 139 0.128 147 17 0.116 0
OASL OASL Q15646 2'-5'-oligoadenylate synthase-like protein chr12 GO:0050776 Not Cancer Driver No 76 0.148 8 4 0.5 0
OTOP1 OTOP1 Q7RTM1 Proton channel OTOP1 chr4 GO:0050776 Not Cancer Driver No 104 0.17 89 11 0.124 0
OTUD4_ENST00000447906 OTUD4 Q01804 OTU domain-containing protein 4 chr4 GO:0050776 Not Cancer Driver No 148 0.133 788 120 0.152 0
OTULIN OTULIN Q96BN8 Ubiquitin thioesterase otulin chr5 GO:0050776 Not Cancer Driver No 47 0.134 97 5 0.052 2
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0050776 Not Cancer Driver No 51 0.086 14 2 0.143 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0050776 Not Cancer Driver No 57 0.105 299 30 0.1 2
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 GO:0050776 Compendium Yes 89 0.17 242 49 0.202 0
PAK3_ENST00000262836 PAK3 O75914 Serine/threonine-protein kinase PAK 3 chrX GO:0050776 Not Cancer Driver No 127 0.227 286 64 0.224 2
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0050776 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARP14 PARP14 Q460N5 Protein mono-ADP-ribosyltransferase PARP14 chr3 GO:0050776 Not Cancer Driver No 221 0.123 301 57 0.189 0
PARP3_ENST00000431474 PARP3 Q9Y6F1 Protein mono-ADP-ribosyltransferase PARP3 chr3 GO:0050776 Not Cancer Driver No 70 0.131 269 38 0.141 0
PARP9 PARP9 Q8IXQ6 Protein mono-ADP-ribosyltransferase PARP9 chr3 GO:0050776 Not Cancer Driver No 110 0.129 45 3 0.067 0
PAWR PAWR Q96IZ0 PRKC apoptosis WT1 regulator protein chr12 GO:0050776 Not Cancer Driver No 35 0.103 327 33 0.101 0
PAXIP1 PAXIP1 Q6ZW49 PAX-interacting protein 1 chr7 GO:0050776 Not Cancer Driver No 120 0.112 461 39 0.085 0
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0050776 Not Cancer Driver No 142 0.228 110 28 0.255 1
PDCD1 PDCD1 Q15116 Programmed cell death protein 1 chr2 GO:0050776 Not Cancer Driver No 56 0.194 141 37 0.262 0
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0050776 Not Cancer Driver No 33 0.059 121 12 0.099 0
PELI1 PELI1 Q96FA3 E3 ubiquitin-protein ligase pellino homolog 1 chr2 GO:0050776 Not Cancer Driver No 47 0.112 167 17 0.102 0
PGC PGC P20142 Gastricsin chr6 GO:0050776 Not Cancer Driver No 60 0.155 20 1 0.05 0
PGLYRP1 PGLYRP1 O75594 Peptidoglycan recognition protein 1 chr19 GO:0050776 Not Cancer Driver No 34 0.173 4 0 0.0 0
PGLYRP2 PGLYRP2 Q96PD5 N-acetylmuramoyl-L-alanine amidase chr19 GO:0050776 Not Cancer Driver No 111 0.193 160 28 0.175 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 GO:0050776 Not Cancer Driver No 31 0.104 26 4 0.154 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:0050776 Not Cancer Driver No 37 0.136 4 1 0.25 0
PHPT1 PHPT1 Q9NRX4 14 kDa phosphohistidine phosphatase chr9 GO:0050776 Not Cancer Driver No 13 0.104 6 0 0.0 0
PIANP PIANP Q8IYJ0 PILR alpha-associated neural protein chr12 GO:0050776 Not Cancer Driver No 45 0.16 217 38 0.175 0
PIGR PIGR P01833 Polymeric immunoglobulin receptor chr1 GO:0050776 Not Cancer Driver No 126 0.165 177 37 0.209 0
PIK3AP1 PIK3AP1 Q6ZUJ8 Phosphoinositide 3-kinase adapter protein 1 chr10 GO:0050776 Not Cancer Driver No 141 0.175 406 81 0.2 0
PIK3R6_ENST00000614407 PIK3R6 Q5UE93 Phosphoinositide 3-kinase regulatory subunit 6 chr17 GO:0050776 Not Cancer Driver No 100 0.133 156 26 0.167 0
PJA2 PJA2 O43164 E3 ubiquitin-protein ligase Praja-2 chr5 GO:0050776 Not Cancer Driver No 80 0.113 598 66 0.11 0
PKN1_ENST00000242783 PKN1 Q16512 Serine/threonine-protein kinase N1 chr19 GO:0050776 Not Cancer Driver No 120 0.127 459 54 0.118 0
PLA2G2D PLA2G2D Q9UNK4 Group IID secretory phospholipase A2 chr1 GO:0050776 Not Cancer Driver No 27 0.186 0 0 0.0 0
PLA2G3 PLA2G3 Q9NZ20 Group 3 secretory phospholipase A2 chr22 GO:0050776 Not Cancer Driver No 115 0.226 175 39 0.223 0
PLA2G4A PLA2G4A P47712 Cytosolic phospholipase A2 chr1 GO:0050776 Not Cancer Driver No 149 0.199 129 28 0.217 1
PLA2G5 PLA2G5 P39877 Phospholipase A2 group V chr1 GO:0050776 Not Cancer Driver No 24 0.174 0 0 0.0 2
PLA2G6 PLA2G6 O60733 85/88 kDa calcium-independent phospholipase A2 chr22 GO:0050776 Not Cancer Driver No 108 0.134 148 23 0.155 11
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 GO:0050776 Census, Compendium Yes 158 0.122 186 21 0.113 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0050776 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLCL2 PLCL2 Q9UPR0 Inactive phospholipase C-like protein 2 chr3 GO:0050776 Not Cancer Driver No 185 0.164 274 31 0.113 0
PLD2 PLD2 O14939 Phospholipase D2 chr17 GO:0050776 Not Cancer Driver No 107 0.115 97 8 0.082 0
PLK2 PLK2 Q9NYY3 Serine/threonine-protein kinase PLK2 chr5 GO:0050776 Not Cancer Driver No 92 0.134 178 21 0.118 0
PLPP4 PLPP4 Q5VZY2 Phospholipid phosphatase 4 chr10 GO:0050776 Not Cancer Driver No 59 0.218 14 1 0.071 0
PLSCR1 PLSCR1 O15162 Phospholipid scramblase 1 chr3 GO:0050776 Not Cancer Driver No 43 0.135 92 13 0.141 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0050776 Census Yes 72 0.143 44 4 0.091 3
PPP2R3C PPP2R3C Q969Q6 Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma chr14 GO:0050776 Not Cancer Driver No 44 0.097 30 3 0.1 0
PPP3CB_ENST00000360663 PPP3CB P16298 Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform chr10 GO:0050776 Not Cancer Driver No 67 0.128 139 18 0.129 0
PRAM1 PRAM1 Q96QH2 PML-RARA-regulated adapter molecule 1 chr19 GO:0050776 Not Cancer Driver No 118 0.176 628 117 0.186 0
PRKCB_ENST00000321728 PRKCB P05771 Protein kinase C beta type chr16 GO:0050776 Census, Compendium Yes 205 0.306 148 40 0.27 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0050776 Compendium Yes 79 0.117 43 9 0.209 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 GO:0050776 Not Cancer Driver No 107 0.145 170 26 0.153 0
PRKCH PRKCH P24723 Protein kinase C eta type chr14 GO:0050776 Not Cancer Driver No 89 0.13 92 13 0.141 0
PRKCQ PRKCQ Q04759 Protein kinase C theta type chr10 GO:0050776 Not Cancer Driver No 147 0.208 28 9 0.321 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0050776 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0050776 Compendium Yes 118 0.134 246 34 0.138 0
PRNP PRNP P04156 Major prion protein chr20 GO:0050776 Not Cancer Driver No 36 0.142 115 7 0.061 18
PSG9 PSG9 Q00887 Pregnancy-specific beta-1-glycoprotein 9 chr19 GO:0050776 Not Cancer Driver No 125 0.293 40 8 0.2 0
PSMA1_ENST00000396394 PSMA1 P25786 Proteasome subunit alpha type-1 chr11 GO:0050776 Not Cancer Driver No 48 0.183 51 9 0.176 0
PSMB4 PSMB4 P28070 Proteasome subunit beta type-4 chr1 GO:0050776 Not Cancer Driver No 23 0.087 18 2 0.111 0
PTAFR_ENST00000305392 PTAFR P25105 Platelet-activating factor receptor chr1 GO:0050776 Not Cancer Driver No 42 0.123 0 0 0.0 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:0050776 Not Cancer Driver No 134 0.127 425 55 0.129 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:0050776 Not Cancer Driver No 49 0.113 140 25 0.179 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0050776 Census, Compendium Yes 129 0.218 260 38 0.146 60
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:0050776 Not Cancer Driver No 57 0.137 120 14 0.117 0
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0050776 Not Cancer Driver No 141 0.175 364 62 0.17 4
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:0050776 Census, Compendium Yes 73 0.123 192 25 0.13 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0050776 Census, Compendium Yes 315 0.241 462 107 0.232 0
PTPRD PTPRD P23468 Receptor-type tyrosine-protein phosphatase delta chr9 GO:0050776 Census, Compendium Yes 577 0.302 747 219 0.293 0
PTPRJ PTPRJ Q12913 Receptor-type tyrosine-protein phosphatase eta chr11 GO:0050776 Not Cancer Driver No 184 0.138 401 61 0.152 0
PTPRS PTPRS Q13332 Receptor-type tyrosine-protein phosphatase S chr19 GO:0050776 Not Cancer Driver No 250 0.128 829 111 0.134 0
PUM1_ENST00000257075 PUM1 Q14671 Pumilio homolog 1 chr1 GO:0050776 Not Cancer Driver No 150 0.126 640 77 0.12 3
PUM2_ENST00000403432 PUM2 Q8TB72 Pumilio homolog 2 chr2 GO:0050776 Not Cancer Driver No 132 0.124 575 83 0.144 0
PVR PVR P15151 Poliovirus receptor chr19 GO:0050776 Not Cancer Driver No 39 0.094 120 19 0.158 0
PVRIG PVRIG Q6DKI7 Transmembrane protein PVRIG chr7 GO:0050776 Not Cancer Driver No 41 0.126 173 28 0.162 0
RAB11FIP2_ENST00000355624 RAB11FIP2 Q7L804 Rab11 family-interacting protein 2 chr10 GO:0050776 Not Cancer Driver No 66 0.129 356 43 0.121 0
RAB29 RAB29 O14966 Ras-related protein Rab-7L1 chr1 GO:0050776 Not Cancer Driver No 28 0.138 18 3 0.167 0
RABGEF1_ENST00000284957 RABGEF1 Q9UJ41 Rab5 GDP/GTP exchange factor chr7 GO:0050776 Not Cancer Driver No 73 0.149 175 35 0.2 0
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 GO:0050776 Not Cancer Driver No 31 0.161 0 0 0.0 2
RAET1G RAET1G Q6H3X3 UL-16 binding protein 5 chr6 GO:0050776 Not Cancer Driver No 41 0.123 62 10 0.161 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0050776 Census, Compendium Yes 70 0.152 167 14 0.084 0
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 GO:0050776 Not Cancer Driver No 158 0.139 796 115 0.144 0
RC3H2_ENST00000357244 RC3H2 Q9HBD1 Roquin-2 chr9 GO:0050776 Not Cancer Driver No 128 0.107 703 81 0.115 0
REG3G REG3G Q6UW15 Regenerating islet-derived protein 3-gamma chr2 GO:0050776 Not Cancer Driver No 81 0.463 17 4 0.235 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:0050776 Compendium Yes 75 0.136 400 48 0.12 0
RFTN1 RFTN1 Q14699 Raftlin chr3 GO:0050776 Not Cancer Driver No 87 0.151 319 44 0.138 0
RHBDF2 RHBDF2 Q6PJF5 Inactive rhomboid protein 2 chr17 GO:0050776 Not Cancer Driver No 93 0.109 284 36 0.127 2
RIF1 RIF1 Q5UIP0 Telomere-associated protein RIF1 chr2 GO:0050776 Not Cancer Driver No 287 0.116 1355 164 0.121 0
RIOK3 RIOK3 O14730 Serine/threonine-protein kinase RIO3 chr18 GO:0050776 Not Cancer Driver No 58 0.112 225 21 0.093 0
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0050776 Not Cancer Driver No 63 0.117 143 20 0.14 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:0050776 Not Cancer Driver No 66 0.127 295 39 0.132 0
RNF125 RNF125 Q96EQ8 E3 ubiquitin-protein ligase RNF125 chr18 GO:0050776 Not Cancer Driver No 35 0.151 26 1 0.038 3
RNF135 RNF135 Q8IUD6 E3 ubiquitin-protein ligase RNF135 chr17 GO:0050776 Not Cancer Driver No 40 0.093 139 11 0.079 0
RNF185 RNF185 Q96GF1 E3 ubiquitin-protein ligase RNF185 chr22 GO:0050776 Not Cancer Driver No 25 0.13 82 15 0.183 0
RPS19_ENST00000600467 RPS19 P39019 40S ribosomal protein S19 chr19 GO:0050776 Not Cancer Driver No 15 0.103 61 3 0.049 23
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0050776 Not Cancer Driver No 22 0.091 48 4 0.083 0
RSAD2 RSAD2 Q8WXG1 Radical S-adenosyl methionine domain-containing protein 2 chr2 GO:0050776 Not Cancer Driver No 68 0.188 22 1 0.045 0
RTN4 RTN4 Q9NQC3 Reticulon-4 chr2 GO:0050776 Not Cancer Driver No 121 0.102 866 82 0.095 0
SAMHD1 SAMHD1 Q9Y3Z3 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 chr20 GO:0050776 Not Cancer Driver No 104 0.166 91 14 0.154 13
SAMSN1_ENST00000400566 SAMSN1 Q9NSI8 SAM domain-containing protein SAMSN-1 chr21 GO:0050776 Not Cancer Driver No 112 0.3 291 85 0.292 0
SARM1 SARM1 Q6SZW1 NAD(+) hydrolase SARM1 chr17 GO:0050776 Not Cancer Driver No 36 0.05 80 4 0.05 0
SASH3 SASH3 O75995 SAM and SH3 domain-containing protein 3 chrX GO:0050776 Not Cancer Driver No 59 0.155 327 49 0.15 0
SCARA3 SCARA3 Q6AZY7 Scavenger receptor class A member 3 chr8 GO:0050776 Not Cancer Driver No 80 0.132 230 29 0.126 0
SCIMP SCIMP Q6UWF3 SLP adapter and CSK-interacting membrane protein chr17 GO:0050776 Not Cancer Driver No 10 0.069 73 9 0.123 0
SEC14L1_ENST00000436233 SEC14L1 Q92503 SEC14-like protein 1 chr17 GO:0050776 Not Cancer Driver No 104 0.145 82 16 0.195 0
SELENOS SELENOS Q9BQE4 Selenoprotein S chr15 GO:0050776 Not Cancer Driver No 7 0.037 122 6 0.049 0
SERPINB4 SERPINB4 P48594 Serpin B4 chr18 GO:0050776 Not Cancer Driver No 120 0.308 48 18 0.375 0
SERPINB9 SERPINB9 P50453 Serpin B9 chr6 GO:0050776 Not Cancer Driver No 64 0.17 22 2 0.091 0
SERPING1 SERPING1 P05155 Plasma protease C1 inhibitor chr11 GO:0050776 Not Cancer Driver No 74 0.148 113 13 0.115 40
SH2D1A SH2D1A O60880 SH2 domain-containing protein 1A chrX GO:0050776 Not Cancer Driver No 40 0.312 24 8 0.333 19
SH2D1B SH2D1B O14796 SH2 domain-containing protein 1B chr1 GO:0050776 Not Cancer Driver No 34 0.258 0 0 0.0 0
SHLD1 SHLD1 Q8IYI0 Shieldin complex subunit 1 chr20 GO:0050776 Not Cancer Driver No 30 0.146 116 20 0.172 0
SHLD2_ENST00000298784 SHLD2 Q86V20 Shieldin complex subunit 2 chr10 GO:0050776 Not Cancer Driver No 84 0.101 157 14 0.089 0
SHLD3 SHLD3 Q6ZNX1 Shieldin complex subunit 3 chr5 GO:0050776 Not Cancer Driver No 3 0.012 81 1 0.012 0
SLA2 SLA2 Q9H6Q3 Src-like-adapter 2 chr20 GO:0050776 Not Cancer Driver No 32 0.123 43 9 0.209 0
SLAMF1_ENST00000302035 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 GO:0050776 Not Cancer Driver No 82 0.245 64 10 0.156 0
SLAMF8 SLAMF8 Q9P0V8 SLAM family member 8 chr1 GO:0050776 Not Cancer Driver No 63 0.221 20 2 0.1 0
SLC11A1 SLC11A1 P49279 Natural resistance-associated macrophage protein 1 chr2 GO:0050776 Not Cancer Driver No 79 0.144 47 5 0.106 0
SLC15A2 SLC15A2 Q16348 Solute carrier family 15 member 2 chr3 GO:0050776 Not Cancer Driver No 153 0.21 37 7 0.189 0
SLC15A3 SLC15A3 Q8IY34 Solute carrier family 15 member 3 chr11 GO:0050776 Not Cancer Driver No 63 0.108 43 1 0.023 0
SLC15A4 SLC15A4 Q8N697 Solute carrier family 15 member 4 chr12 GO:0050776 Not Cancer Driver No 66 0.114 23 4 0.174 0
SLC22A13 SLC22A13 Q9Y226 Solute carrier family 22 member 13 chr3 GO:0050776 Not Cancer Driver No 55 0.1 32 3 0.094 0
SLC39A10_ENST00000359634 SLC39A10 Q9ULF5 Zinc transporter ZIP10 chr2 GO:0050776 Not Cancer Driver No 111 0.134 417 63 0.151 0
SLC46A2 SLC46A2 Q9BY10 Thymic stromal cotransporter homolog chr9 GO:0050776 Not Cancer Driver No 45 0.095 36 3 0.083 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0050776 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0050776 Not Cancer Driver No 40 0.094 139 0 0.0 0
SMPDL3B SMPDL3B Q92485 Acid sphingomyelinase-like phosphodiesterase 3b chr1 GO:0050776 Not Cancer Driver No 61 0.134 22 7 0.318 0
SNX4 SNX4 O95219 Sorting nexin-4 chr3 GO:0050776 Not Cancer Driver No 31 0.069 101 5 0.05 0
SOCS1 SOCS1 O15524 Suppressor of cytokine signaling 1 chr16 GO:0050776 Census, Compendium Yes 22 0.104 66 3 0.045 2
SOCS5 SOCS5 O75159 Suppressor of cytokine signaling 5 chr2 GO:0050776 Not Cancer Driver No 84 0.157 297 46 0.155 0
SOS1_ENST00000402219 SOS1 Q07889 Son of sevenless homolog 1 chr2 GO:0050776 Compendium Yes 197 0.148 458 62 0.135 38
SPHK2 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 GO:0050776 Not Cancer Driver No 82 0.125 293 39 0.133 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0050776 Not Cancer Driver No 46 0.17 187 34 0.182 0
SPINK5_ENST00000256084 SPINK5 Q9NQ38 Serine protease inhibitor Kazal-type 5 chr5 GO:0050776 Not Cancer Driver No 168 0.158 590 102 0.173 0
SPNS2 SPNS2 Q8IVW8 Sphingosine-1-phosphate transporter SPNS2 chr17 GO:0050776 Not Cancer Driver No 54 0.098 82 0 0.0 0
SPN_ENST00000395389 SPN P16150 Leukosialin chr16 GO:0050776 Not Cancer Driver No 46 0.115 357 35 0.098 0
SPPL2A SPPL2A Q8TCT8 Signal peptide peptidase-like 2A chr15 GO:0050776 Not Cancer Driver No 55 0.106 3 0 0.0 0
SPPL2B SPPL2B Q8TCT7 Signal peptide peptidase-like 2B chr19 GO:0050776 Not Cancer Driver No 68 0.115 99 17 0.172 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0050776 Census Yes 53 0.099 130 11 0.085 1
STAP1_ENST00000396225 STAP1 Q9ULZ2 Signal-transducing adaptor protein 1 chr4 GO:0050776 Not Cancer Driver No 66 0.224 103 18 0.175 0
STAT2 STAT2 P52630 Signal transducer and activator of transcription 2 chr12 GO:0050776 Not Cancer Driver No 90 0.106 178 22 0.124 2
STAT6_ENST00000543873 STAT6 P42226 Signal transducer and activator of transcription 6 chr12 GO:0050776 Census, Compendium Yes 106 0.125 325 44 0.135 0
STX4 STX4 Q12846 Syntaxin-4 chr16 GO:0050776 Not Cancer Driver No 50 0.168 152 20 0.132 0
STX7 STX7 O15400 Syntaxin-7 chr6 GO:0050776 Not Cancer Driver No 29 0.111 164 14 0.085 0
STXBP1_ENST00000373299 STXBP1 P61764 Syntaxin-binding protein 1 chr9 GO:0050776 Not Cancer Driver No 97 0.163 111 23 0.207 18
STXBP2_ENST00000221283 STXBP2 Q15833 Syntaxin-binding protein 2 chr19 GO:0050776 Not Cancer Driver No 77 0.13 80 13 0.163 5
SUPT6H SUPT6H Q7KZ85 Transcription elongation factor SPT6 chr17 GO:0050776 Not Cancer Driver No 222 0.129 761 107 0.141 0
SUSD4 SUSD4 Q5VX71 Sushi domain-containing protein 4 chr1 GO:0050776 Not Cancer Driver No 85 0.173 134 27 0.201 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0050776 Census Yes 96 0.151 131 27 0.206 5
TAPBPL TAPBPL Q9BX59 Tapasin-related protein chr12 GO:0050776 Not Cancer Driver No 53 0.113 67 8 0.119 0
TAPBP_ENST00000434618 TAPBP O15533 Tapasin chr6 GO:0050776 Not Cancer Driver No 58 0.129 168 26 0.155 0
TBK1 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 GO:0050776 Not Cancer Driver No 101 0.139 42 5 0.119 12
TBX21 TBX21 Q9UL17 T-box transcription factor TBX21 chr17 GO:0050776 Not Cancer Driver No 70 0.131 348 50 0.144 0
TESPA1 TESPA1 A2RU30 Protein TESPA1 chr12 GO:0050776 Not Cancer Driver No 127 0.244 284 84 0.296 0
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 GO:0050776 Census Yes 89 0.117 80 6 0.075 1
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0050776 Not Cancer Driver No 41 0.105 41 4 0.098 10
THOC1 THOC1 Q96FV9 THO complex subunit 1 chr18 GO:0050776 Not Cancer Driver No 55 0.084 280 26 0.093 0
THY1 THY1 P04216 Thy-1 membrane glycoprotein chr11 GO:0050776 Not Cancer Driver No 24 0.149 5 0 0.0 0
TICAM1 TICAM1 Q8IUC6 TIR domain-containing adapter molecule 1 chr19 GO:0050776 Not Cancer Driver No 92 0.129 443 66 0.149 1
TICAM2 TICAM2 Q86XR7 TIR domain-containing adapter molecule 2 chr5 GO:0050776 Not Cancer Driver No 35 0.149 88 10 0.114 0
TIFA_ENST00000500655 TIFA Q96CG3 TRAF-interacting protein with FHA domain-containing protein A chr4 GO:0050776 Not Cancer Driver No 17 0.092 32 5 0.156 0
TIRAP_ENST00000392680 TIRAP P58753 Toll/interleukin-1 receptor domain-containing adapter protein chr11 GO:0050776 Not Cancer Driver No 28 0.127 80 6 0.075 0
TKFC TKFC Q3LXA3 Triokinase/FMN cyclase chr11 GO:0050776 Not Cancer Driver No 66 0.115 91 14 0.154 2
TLR10_ENST00000508334 TLR10 Q9BXR5 Toll-like receptor 10 chr4 GO:0050776 Not Cancer Driver No 122 0.15 9 1 0.111 0
TLR1_ENST00000502213 TLR1 Q15399 Toll-like receptor 1 chr4 GO:0050776 Not Cancer Driver No 107 0.136 1 0 0.0 0
TLR2 TLR2 O60603 Toll-like receptor 2 chr4 GO:0050776 Not Cancer Driver No 108 0.138 0 0 0.0 0
TLR3 TLR3 O15455 Toll-like receptor 3 chr4 GO:0050776 Not Cancer Driver No 123 0.136 0 0 0.0 1
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0050776 Not Cancer Driver No 292 0.348 0 0 0.0 0
TLR5_ENST00000366881 TLR5 O60602 Toll-like receptor 5 chr1 GO:0050776 Not Cancer Driver No 148 0.172 16 3 0.188 0
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:0050776 Not Cancer Driver No 99 0.124 1 0 0.0 0
TLR7 TLR7 Q9NYK1 Toll-like receptor 7 chrX GO:0050776 Not Cancer Driver No 182 0.173 14 1 0.071 1
TLR8_ENST00000218032 TLR8 Q9NR97 Toll-like receptor 8 chrX GO:0050776 Not Cancer Driver No 180 0.173 30 7 0.233 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:0050776 Not Cancer Driver No 141 0.137 35 3 0.086 0
TMEM173 STING1 Q86WV6 Stimulator of interferon genes protein chr5 GO:0050776 Not Cancer Driver No 46 0.121 66 13 0.197 3
TNF TNF P01375 Tumor necrosis factor chr6 GO:0050776 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:0050776 Census, Compendium Yes 98 0.124 231 33 0.143 1
TNFRSF14 TNFRSF14 Q92956 Tumor necrosis factor receptor superfamily member 14 chr1 GO:0050776 Census, Compendium Yes 33 0.117 54 8 0.148 0
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 GO:0050776 Not Cancer Driver No 48 0.104 229 28 0.122 0
TNFSF13 TNFSF13 O75888 Tumor necrosis factor ligand superfamily member 13 chr17 GO:0050776 Not Cancer Driver No 14 0.056 109 6 0.055 0
TNFSF13B TNFSF13B Q9Y275 Tumor necrosis factor ligand superfamily member 13B chr13 GO:0050776 Not Cancer Driver No 41 0.144 91 15 0.165 0
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 GO:0050776 Not Cancer Driver No 28 0.153 1 0 0.0 0
TNIP1_ENST00000522226 TNIP1 Q15025 TNFAIP3-interacting protein 1 chr5 GO:0050776 Not Cancer Driver No 85 0.134 625 83 0.133 0
TNIP2 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 GO:0050776 Not Cancer Driver No 43 0.1 316 36 0.114 0
TNIP3_ENST00000057513 TNIP3 Q96KP6 TNFAIP3-interacting protein 3 chr4 GO:0050776 Not Cancer Driver No 97 0.298 249 72 0.289 0
TP53BP1_ENST00000263801 TP53BP1 Q12888 TP53-binding protein 1 chr15 GO:0050776 Not Cancer Driver No 227 0.115 1632 190 0.116 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0050776 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAF3_ENST00000392745 TRAF3 Q13114 TNF receptor-associated factor 3 chr14 GO:0050776 Compendium Yes 61 0.107 101 9 0.089 1
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0050776 Not Cancer Driver No 67 0.128 62 7 0.113 0
TRAFD1_ENST00000412615 TRAFD1 O14545 TRAF-type zinc finger domain-containing protein 1 chr12 GO:0050776 Not Cancer Driver No 55 0.095 374 32 0.086 0
TRAT1 TRAT1 Q6PIZ9 T-cell receptor-associated transmembrane adapter 1 chr3 GO:0050776 Not Cancer Driver No 86 0.462 129 67 0.519 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0050776 Not Cancer Driver No 43 0.187 27 2 0.074 1
TREML4_ENST00000448827 TREML4 Q6UXN2 Trem-like transcript 4 protein chr6 GO:0050776 Not Cancer Driver No 43 0.215 22 6 0.273 0
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0050776 Not Cancer Driver No 26 0.083 98 10 0.102 18
TRIM15 TRIM15 Q9C019 Tripartite motif-containing protein 15 chr6 GO:0050776 Not Cancer Driver No 69 0.148 79 11 0.139 0
TRIM21 TRIM21 P19474 E3 ubiquitin-protein ligase TRIM21 chr11 GO:0050776 Not Cancer Driver No 85 0.179 49 7 0.143 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 GO:0050776 Not Cancer Driver No 59 0.094 225 20 0.089 0
TRIM27 TRIM27 P14373 Zinc finger protein RFP chr6 GO:0050776 Census Yes 59 0.115 87 11 0.126 0
TRIM41 TRIM41 Q8WV44 E3 ubiquitin-protein ligase TRIM41 chr5 GO:0050776 Not Cancer Driver No 69 0.11 385 38 0.099 0
TRIM56 TRIM56 Q9BRZ2 E3 ubiquitin-protein ligase TRIM56 chr7 GO:0050776 Not Cancer Driver No 110 0.146 217 36 0.166 0
TRIM62 TRIM62 Q9BVG3 E3 ubiquitin-protein ligase TRIM62 chr1 GO:0050776 Not Cancer Driver No 58 0.122 80 14 0.175 0
TRIM6_ENST00000278302 TRIM6 Q9C030 Tripartite motif-containing protein 6 chr11 GO:0050776 Not Cancer Driver No 86 0.176 47 15 0.319 0
TRPM4 TRPM4 Q8TD43 Transient receptor potential cation channel subfamily M member 4 chr19 GO:0050776 Not Cancer Driver No 152 0.125 149 18 0.121 12
TSPAN6 TSPAN6 O43657 Tetraspanin-6 chrX GO:0050776 Not Cancer Driver No 34 0.139 0 0 0.0 0
TTLL12 TTLL12 Q14166 Tubulin--tyrosine ligase-like protein 12 chr22 GO:0050776 Not Cancer Driver No 69 0.107 100 6 0.06 0
TXK TXK P42681 Tyrosine-protein kinase TXK chr4 GO:0050776 Not Cancer Driver No 87 0.165 61 9 0.148 0
TYRO3 TYRO3 Q06418 Tyrosine-protein kinase receptor TYRO3 chr15 GO:0050776 Not Cancer Driver No 119 0.134 197 17 0.086 0
TYROBP TYROBP O43914 TYRO protein tyrosine kinase-binding protein chr19 GO:0050776 Not Cancer Driver No 24 0.212 28 8 0.286 0
UBASH3A UBASH3A P57075 Ubiquitin-associated and SH3 domain-containing protein A chr21 GO:0050776 Not Cancer Driver No 101 0.153 27 8 0.296 0
UBE2K UBE2K P61086 Ubiquitin-conjugating enzyme E2 K chr4 GO:0050776 Not Cancer Driver No 24 0.12 33 3 0.091 0
UBQLN1 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 GO:0050776 Not Cancer Driver No 64 0.109 543 58 0.107 0
UFD1 UFD1 Q92890 Ubiquitin recognition factor in ER-associated degradation protein 1 chr22 GO:0050776 Not Cancer Driver No 26 0.085 100 7 0.07 0
UNC13D UNC13D Q70J99 Protein unc-13 homolog D chr17 GO:0050776 Not Cancer Driver No 120 0.11 248 30 0.121 0
UNC93B1 UNC93B1 Q9H1C4 Protein unc-93 homolog B1 chr11 GO:0050776 Not Cancer Driver No 57 0.095 127 5 0.039 0
USP15 USP15 Q9Y4E8 Ubiquitin carboxyl-terminal hydrolase 15 chr12 GO:0050776 Not Cancer Driver No 136 0.139 259 39 0.151 0
USP17L2 USP17L2 Q6R6M4 Ubiquitin carboxyl-terminal hydrolase 17 chr8 GO:0050776 Not Cancer Driver No 105 0.198 201 54 0.269 0
USP18 USP18 Q9UMW8 Ubl carboxyl-terminal hydrolase 18 chr22 GO:0050776 Not Cancer Driver No 34 0.091 29 8 0.276 0
USP27X USP27X A6NNY8 Ubiquitin carboxyl-terminal hydrolase 27 chrX GO:0050776 Not Cancer Driver No 31 0.071 69 3 0.043 1
USP29_ENST00000598197 USP29 Q9HBJ7 Ubiquitin carboxyl-terminal hydrolase 29 chr19 GO:0050776 Not Cancer Driver No 291 0.316 432 132 0.306 0
VAMP7_ENST00000286448 VAMP7 P51809 Vesicle-associated membrane protein 7 chrX GO:0050776 Not Cancer Driver No 38 0.173 4 1 0.25 0
VAMP8 VAMP8 Q9BV40 Vesicle-associated membrane protein 8 chr2 GO:0050776 Not Cancer Driver No 9 0.09 27 0 0.0 0
VAV1 VAV1 P15498 Proto-oncogene vav chr19 GO:0050776 Census, Compendium Yes 165 0.195 113 19 0.168 0
VAV2 VAV2 P52735 Guanine nucleotide exchange factor VAV2 chr9 GO:0050776 Not Cancer Driver No 127 0.145 135 17 0.126 0
VAV3 VAV3 Q9UKW4 Guanine nucleotide exchange factor VAV3 chr1 GO:0050776 Not Cancer Driver No 153 0.181 102 18 0.176 0
VSIG4 VSIG4 Q9Y279 V-set and immunoglobulin domain-containing protein 4 chrX GO:0050776 Not Cancer Driver No 73 0.183 70 13 0.186 0
VSIR VSIR Q9H7M9 V-type immunoglobulin domain-containing suppressor of T-cell activation chr10 GO:0050776 Not Cancer Driver No 52 0.167 135 19 0.141 0
WAS WAS P42768 Wiskott-Aldrich syndrome protein chrX GO:0050776 Census, Compendium Yes 75 0.149 400 55 0.138 30
WDFY1 WDFY1 Q8IWB7 WD repeat and FYVE domain-containing protein 1 chr2 GO:0050776 Not Cancer Driver No 51 0.124 24 2 0.083 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0050776 Not Cancer Driver No 66 0.174 0 0 0.0 2
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0050776 Not Cancer Driver No 19 0.073 169 9 0.053 0
XCL1 XCL1 P47992 Lymphotactin chr1 GO:0050776 Not Cancer Driver No 28 0.246 35 11 0.314 0
XIAP_ENST00000434753 XIAP P98170 E3 ubiquitin-protein ligase XIAP chrX GO:0050776 Not Cancer Driver No 89 0.179 55 6 0.109 0
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 GO:0050776 Not Cancer Driver No 65 0.12 62 10 0.161 0
YTHDF2_ENST00000542507 YTHDF2 Q9Y5A9 YTH domain-containing family protein 2 chr1 GO:0050776 Not Cancer Driver No 67 0.116 376 44 0.117 0
YTHDF3_ENST00000539294 YTHDF3 Q7Z739 YTH domain-containing family protein 3 chr8 GO:0050776 Not Cancer Driver No 74 0.126 409 51 0.125 0
ZBP1 ZBP1 Q9H171 Z-DNA-binding protein 1 chr20 GO:0050776 Not Cancer Driver No 97 0.226 385 80 0.208 0
ZBTB1 ZBTB1 Q9Y2K1 Zinc finger and BTB domain-containing protein 1 chr14 GO:0050776 Not Cancer Driver No 70 0.098 271 27 0.1 0
ZBTB7B_ENST00000368426 ZBTB7B O15156 Zinc finger and BTB domain-containing protein 7B chr1 GO:0050776 Compendium Yes 103 0.191 353 70 0.198 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0050776 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZCCHC3 ZCCHC3 Q9NUD5 Zinc finger CCHC domain-containing protein 3 chr20 GO:0050776 Not Cancer Driver No 28 0.069 160 1 0.006 0
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 GO:0050776 Not Cancer Driver No 89 0.124 462 63 0.136 0
ZP3 ZP3 P21754 Zona pellucida sperm-binding protein 3 chr7 GO:0050776 Not Cancer Driver No 55 0.13 56 11 0.196 1
ZP4 ZP4 Q12836 Zona pellucida sperm-binding protein 4 chr1 GO:0050776 Not Cancer Driver No 189 0.35 46 15 0.326 0