Total number of protein in "GO:0050773" GO term: 75
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0050773 | Census, Compendium | Yes | 139 | 0.123 | 604 | 73 | 0.121 | 2 |
| ACTR2_ENST00000260641 | ACTR2 | P61160 | Actin-related protein 2 | chr2 | GO:0050773 | Not Cancer Driver | No | 51 | 0.129 | 6 | 2 | 0.333 | 0 |
| ALK | ALK | Q9UM73 | ALK tyrosine kinase receptor | chr2 | GO:0050773 | Census, Compendium | Yes | 303 | 0.187 | 575 | 114 | 0.198 | 16 |
| ANAPC2 | ANAPC2 | Q9UJX6 | Anaphase-promoting complex subunit 2 | chr9 | GO:0050773 | Not Cancer Driver | No | 104 | 0.127 | 146 | 26 | 0.178 | 0 |
| ANKRD27 | ANKRD27 | Q96NW4 | Ankyrin repeat domain-containing protein 27 | chr19 | GO:0050773 | Not Cancer Driver | No | 145 | 0.138 | 239 | 33 | 0.138 | 0 |
| ARF6 | ARF6 | P62330 | ADP-ribosylation factor 6 | chr14 | GO:0050773 | Not Cancer Driver | No | 18 | 0.103 | 5 | 0 | 0.0 | 0 |
| BAIAP2 | BAIAP2 | Q9UQB8 | Brain-specific angiogenesis inhibitor 1-associated protein 2 | chr17 | GO:0050773 | Not Cancer Driver | No | 85 | 0.154 | 330 | 52 | 0.158 | 0 |
| BCL11A | BCL11A | Q9H165 | B-cell lymphoma/leukemia 11A | chr2 | GO:0050773 | Census, Compendium | Yes | 210 | 0.251 | 677 | 171 | 0.253 | 3 |
| BHLHB9 | BHLHB9 | Q6PI77 | Protein BHLHb9 | chrX | GO:0050773 | Not Cancer Driver | No | 88 | 0.161 | 267 | 38 | 0.142 | 0 |
| BMP5 | BMP5 | P22003 | Bone morphogenetic protein 5 | chr6 | GO:0050773 | Census | Yes | 163 | 0.359 | 112 | 62 | 0.554 | 0 |
| BMP7 | BMP7 | P18075 | Bone morphogenetic protein 7 | chr20 | GO:0050773 | Not Cancer Driver | No | 91 | 0.211 | 69 | 18 | 0.261 | 0 |
| CAMK1D | CAMK1D | Q8IU85 | Calcium/calmodulin-dependent protein kinase type 1D | chr10 | GO:0050773 | Not Cancer Driver | No | 90 | 0.234 | 42 | 14 | 0.333 | 0 |
| CAMK2B | CAMK2B | Q13554 | Calcium/calmodulin-dependent protein kinase type II subunit beta | chr7 | GO:0050773 | Not Cancer Driver | No | 86 | 0.129 | 273 | 28 | 0.103 | 6 |
| CAMSAP2 | CAMSAP2 | Q08AD1 | Calmodulin-regulated spectrin-associated protein 2 | chr1 | GO:0050773 | Not Cancer Driver | No | 176 | 0.118 | 1025 | 127 | 0.124 | 0 |
| CAPRIN1_ENST00000532820 | CAPRIN1 | Q14444 | Caprin-1 | chr11 | GO:0050773 | Not Cancer Driver | No | 84 | 0.118 | 603 | 72 | 0.119 | 0 |
| CARM1 | CARM1 | Q86X55 | Histone-arginine methyltransferase CARM1 | chr19 | GO:0050773 | Not Cancer Driver | No | 62 | 0.102 | 102 | 10 | 0.098 | 0 |
| CDC20 | CDC20 | Q12834 | Cell division cycle protein 20 homolog | chr1 | GO:0050773 | Not Cancer Driver | No | 44 | 0.088 | 198 | 15 | 0.076 | 0 |
| CDKL3 | CDKL3 | Q8IVW4 | Cyclin-dependent kinase-like 3 | chr5 | GO:0050773 | Not Cancer Driver | No | 68 | 0.115 | 278 | 40 | 0.144 | 0 |
| CDKL5_ENST00000623535 | CDKL5 | O76039 | Cyclin-dependent kinase-like 5 | chrX | GO:0050773 | Not Cancer Driver | No | 165 | 0.172 | 685 | 120 | 0.175 | 18 |
| COBL_ENST00000265136 | COBL | O75128 | Protein cordon-bleu | chr7 | GO:0050773 | Not Cancer Driver | No | 233 | 0.185 | 1149 | 216 | 0.188 | 0 |
| CRK | CRK | P46108 | Adapter molecule crk | chr17 | GO:0050773 | Not Cancer Driver | No | 30 | 0.099 | 197 | 23 | 0.117 | 0 |
| CRKL | CRKL | P46109 | Crk-like protein | chr22 | GO:0050773 | Not Cancer Driver | No | 38 | 0.125 | 160 | 25 | 0.156 | 0 |
| CRTC1_ENST00000321949 | CRTC1 | Q6UUV9 | CREB-regulated transcription coactivator 1 | chr19 | GO:0050773 | Census, Compendium | Yes | 63 | 0.099 | 606 | 62 | 0.102 | 0 |
| CSMD3 | CSMD3 | Q7Z407 | CUB and sushi domain-containing protein 3 | chr8 | GO:0050773 | Census | Yes | 1805 | 0.487 | 425 | 199 | 0.468 | 0 |
| CUL7_ENST00000265348 | CUL7 | Q14999 | Cullin-7 | chr6 | GO:0050773 | Not Cancer Driver | No | 188 | 0.111 | 372 | 41 | 0.11 | 3 |
| CUX2 | CUX2 | O14529 | Homeobox protein cut-like 2 | chr12 | GO:0050773 | Not Cancer Driver | No | 277 | 0.186 | 1201 | 212 | 0.177 | 1 |
| CYFIP1_ENST00000610365 | CYFIP1 | Q7L576 | Cytoplasmic FMR1-interacting protein 1 | chr15 | GO:0050773 | Not Cancer Driver | No | 46 | 0.037 | 96 | 0 | 0.0 | 0 |
| DAB2IP_ENST00000408936 | DAB2IP | Q5VWQ8 | Disabled homolog 2-interacting protein | chr9 | GO:0050773 | Not Cancer Driver | No | 131 | 0.11 | 681 | 68 | 0.1 | 0 |
| DBN1_ENST00000309007 | DBN1 | Q16643 | Drebrin | chr5 | GO:0050773 | Not Cancer Driver | No | 84 | 0.129 | 510 | 73 | 0.143 | 0 |
| DBNL_ENST00000448521 | DBNL | Q9UJU6 | Drebrin-like protein | chr7 | GO:0050773 | Not Cancer Driver | No | 46 | 0.107 | 304 | 31 | 0.102 | 0 |
| DCC | DCC | P43146 | Netrin receptor DCC | chr18 | GO:0050773 | Census, Compendium | Yes | 530 | 0.366 | 631 | 215 | 0.341 | 2 |
| DGKG | DGKG | P49619 | Diacylglycerol kinase gamma | chr3 | GO:0050773 | Not Cancer Driver | No | 160 | 0.202 | 182 | 43 | 0.236 | 0 |
| DHX36 | DHX36 | Q9H2U1 | ATP-dependent DNA/RNA helicase DHX36 | chr3 | GO:0050773 | Not Cancer Driver | No | 159 | 0.158 | 222 | 39 | 0.176 | 0 |
| EEF2K | EEF2K | O00418 | Eukaryotic elongation factor 2 kinase | chr16 | GO:0050773 | Not Cancer Driver | No | 104 | 0.143 | 311 | 39 | 0.125 | 0 |
| ELAVL4_ENST00000371821 | ELAVL4 | P26378 | ELAV-like protein 4 | chr1 | GO:0050773 | Not Cancer Driver | No | 118 | 0.306 | 117 | 34 | 0.291 | 0 |
| EPHA4_ENST00000409938 | EPHA4 | P54764 | Ephrin type-A receptor 4 | chr2 | GO:0050773 | Not Cancer Driver | No | 182 | 0.185 | 140 | 24 | 0.171 | 0 |
| EPHB2 | EPHB2 | P29323 | Ephrin type-B receptor 2 | chr1 | GO:0050773 | Not Cancer Driver | No | 186 | 0.176 | 119 | 17 | 0.143 | 7 |
| EZH2_ENST00000460911 | EZH2 | Q15910 | Histone-lysine N-methyltransferase EZH2 | chr7 | GO:0050773 | Census, Compendium | Yes | 120 | 0.161 | 284 | 44 | 0.155 | 11 |
| FBXO31 | FBXO31 | Q5XUX0 | F-box only protein 31 | chr16 | GO:0050773 | Not Cancer Driver | No | 72 | 0.134 | 231 | 30 | 0.13 | 0 |
| FBXW8 | FBXW8 | Q8N3Y1 | F-box/WD repeat-containing protein 8 | chr12 | GO:0050773 | Not Cancer Driver | No | 68 | 0.114 | 120 | 4 | 0.033 | 0 |
| GORASP1 | GORASP1 | Q9BQQ3 | Golgi reassembly-stacking protein 1 | chr3 | GO:0050773 | Not Cancer Driver | No | 49 | 0.111 | 293 | 32 | 0.109 | 0 |
| ID1 | ID1 | P41134 | DNA-binding protein inhibitor ID-1 | chr20 | GO:0050773 | Not Cancer Driver | No | 20 | 0.129 | 17 | 6 | 0.353 | 0 |
| IL1RAPL1 | IL1RAPL1 | Q9NZN1 | Interleukin-1 receptor accessory protein-like 1 | chrX | GO:0050773 | Not Cancer Driver | No | 205 | 0.295 | 77 | 19 | 0.247 | 0 |
| ITPKA | ITPKA | P23677 | Inositol-trisphosphate 3-kinase A | chr15 | GO:0050773 | Not Cancer Driver | No | 28 | 0.061 | 216 | 7 | 0.032 | 0 |
| KHDC3L | KHDC3L | Q587J8 | KH domain-containing protein 3 | chr6 | GO:0050773 | Not Cancer Driver | No | 68 | 0.313 | 121 | 43 | 0.355 | 0 |
| KIAA0319_ENST00000543707 | KIAA0319 | Q5VV43 | Dyslexia-associated protein KIAA0319 | chr6 | GO:0050773 | Not Cancer Driver | No | 204 | 0.19 | 492 | 85 | 0.173 | 0 |
| KNDC1 | KNDC1 | Q76NI1 | Kinase non-catalytic C-lobe domain-containing protein 1 | chr10 | GO:0050773 | Not Cancer Driver | No | 276 | 0.158 | 805 | 124 | 0.154 | 0 |
| LRP8 | LRP8 | Q14114 | Low-density lipoprotein receptor-related protein 8 | chr1 | GO:0050773 | Not Cancer Driver | No | 94 | 0.098 | 190 | 24 | 0.126 | 0 |
| MARK1_ENST00000366917 | MARK1 | Q9P0L2 | Serine/threonine-protein kinase MARK1 | chr1 | GO:0050773 | Not Cancer Driver | No | 161 | 0.203 | 454 | 108 | 0.238 | 0 |
| MFSD2A | MFSD2A | Q8NA29 | Sodium-dependent lysophosphatidylcholine symporter 1 | chr1 | GO:0050773 | Not Cancer Driver | No | 61 | 0.112 | 36 | 4 | 0.111 | 7 |
| NFATC4_ENST00000250373 | NFATC4 | Q14934 | Nuclear factor of activated T-cells, cytoplasmic 4 | chr14 | GO:0050773 | Not Cancer Driver | No | 155 | 0.172 | 685 | 120 | 0.175 | 0 |
| OBSL1 | OBSL1 | O75147 | Obscurin-like protein 1 | chr2 | GO:0050773 | Not Cancer Driver | No | 233 | 0.123 | 553 | 60 | 0.108 | 0 |
| PACSIN1_ENST00000244458 | PACSIN1 | Q9BY11 | Protein kinase C and casein kinase substrate in neurons protein 1 | chr6 | GO:0050773 | Not Cancer Driver | No | 56 | 0.126 | 318 | 47 | 0.148 | 0 |
| PAFAH1B1 | PAFAH1B1 | P43034 | Platelet-activating factor acetylhydrolase IB subunit beta | chr17 | GO:0050773 | Not Cancer Driver | No | 42 | 0.102 | 82 | 11 | 0.134 | 7 |
| PAK3_ENST00000262836 | PAK3 | O75914 | Serine/threonine-protein kinase PAK 3 | chrX | GO:0050773 | Not Cancer Driver | No | 127 | 0.227 | 286 | 64 | 0.224 | 2 |
| PARP6 | PARP6 | Q2NL67 | Protein mono-ADP-ribosyltransferase PARP6 | chr15 | GO:0050773 | Not Cancer Driver | No | 87 | 0.138 | 67 | 13 | 0.194 | 0 |
| PPP3CA | PPP3CA | Q08209 | Protein phosphatase 3 catalytic subunit alpha | chr4 | GO:0050773 | Compendium | Yes | 85 | 0.163 | 140 | 27 | 0.193 | 7 |
| PTN | PTN | P21246 | Pleiotrophin | chr7 | GO:0050773 | Not Cancer Driver | No | 43 | 0.256 | 51 | 11 | 0.216 | 0 |
| PTPRD | PTPRD | P23468 | Receptor-type tyrosine-protein phosphatase delta | chr9 | GO:0050773 | Census, Compendium | Yes | 577 | 0.302 | 747 | 219 | 0.293 | 0 |
| RAB17 | RAB17 | Q9H0T7 | Ras-related protein Rab-17 | chr2 | GO:0050773 | Not Cancer Driver | No | 29 | 0.137 | 43 | 4 | 0.093 | 0 |
| RAB21 | RAB21 | Q9UL25 | Ras-related protein Rab-21 | chr12 | GO:0050773 | Not Cancer Driver | No | 23 | 0.102 | 59 | 4 | 0.068 | 0 |
| RAPGEF2 | RAPGEF2 | Q9Y4G8 | Rap guanine nucleotide exchange factor 2 | chr4 | GO:0050773 | Not Cancer Driver | No | 216 | 0.144 | 803 | 116 | 0.144 | 0 |
| RELN | RELN | P78509 | Reelin | chr7 | GO:0050773 | Not Cancer Driver | No | 761 | 0.22 | 107 | 19 | 0.178 | 7 |
| RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | GO:0050773 | Census, Compendium | Yes | 99 | 0.513 | 46 | 13 | 0.283 | 2 |
| RTN4IP1 | RTN4IP1 | Q8WWV3 | Reticulon-4-interacting protein 1, mitochondrial | chr6 | GO:0050773 | Not Cancer Driver | No | 60 | 0.152 | 15 | 2 | 0.133 | 1 |
| SEZ6 | SEZ6 | Q53EL9 | Seizure protein 6 homolog | chr17 | GO:0050773 | Not Cancer Driver | No | 120 | 0.121 | 345 | 54 | 0.157 | 0 |
| SS18L1 | SS18L1 | O75177 | Calcium-responsive transactivator | chr20 | GO:0050773 | Census | Yes | 53 | 0.134 | 356 | 48 | 0.135 | 0 |
| SS18L2 | SS18L2 | Q9UHA2 | SS18-like protein 2 | chr3 | GO:0050773 | Not Cancer Driver | No | 4 | 0.052 | 7 | 1 | 0.143 | 0 |
| STAU2 | STAU2 | Q9NUL3 | Double-stranded RNA-binding protein Staufen homolog 2 | chr8 | GO:0050773 | Not Cancer Driver | No | 68 | 0.119 | 486 | 54 | 0.111 | 0 |
| TLX2 | TLX2 | O43763 | T-cell leukemia homeobox protein 2 | chr2 | GO:0050773 | Not Cancer Driver | No | 24 | 0.085 | 220 | 15 | 0.068 | 0 |
| TMEM106B | TMEM106B | Q9NUM4 | Transmembrane protein 106B | chr7 | GO:0050773 | Not Cancer Driver | No | 31 | 0.113 | 56 | 4 | 0.071 | 1 |
| TRPC5 | TRPC5 | Q9UL62 | Short transient receptor potential channel 5 | chrX | GO:0050773 | Not Cancer Driver | No | 255 | 0.262 | 148 | 32 | 0.216 | 0 |
| VLDLR | VLDLR | P98155 | Very low-density lipoprotein receptor | chr9 | GO:0050773 | Not Cancer Driver | No | 90 | 0.103 | 55 | 3 | 0.055 | 0 |
| YWHAH | YWHAH | Q04917 | 14-3-3 protein eta | chr22 | GO:0050773 | Not Cancer Driver | No | 15 | 0.061 | 55 | 3 | 0.055 | 0 |
| ZDHHC15 | ZDHHC15 | Q96MV8 | Palmitoyltransferase ZDHHC15 | chrX | GO:0050773 | Not Cancer Driver | No | 81 | 0.24 | 45 | 9 | 0.2 | 0 |