Total number of protein in "GO:0050769" GO term: 184
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACE | ACE | P12821 | Angiotensin-converting enzyme | chr17 | GO:0050769 | Not Cancer Driver | No | 201 | 0.154 | 86 | 8 | 0.093 | 0 |
| ACTR2_ENST00000260641 | ACTR2 | P61160 | Actin-related protein 2 | chr2 | GO:0050769 | Not Cancer Driver | No | 51 | 0.129 | 6 | 2 | 0.333 | 0 |
| ADNP | ADNP | Q9H2P0 | Activity-dependent neuroprotector homeobox protein | chr20 | GO:0050769 | Not Cancer Driver | No | 130 | 0.118 | 615 | 66 | 0.107 | 0 |
| ANAPC2 | ANAPC2 | Q9UJX6 | Anaphase-promoting complex subunit 2 | chr9 | GO:0050769 | Not Cancer Driver | No | 104 | 0.127 | 146 | 26 | 0.178 | 0 |
| ANKRD27 | ANKRD27 | Q96NW4 | Ankyrin repeat domain-containing protein 27 | chr19 | GO:0050769 | Not Cancer Driver | No | 145 | 0.138 | 239 | 33 | 0.138 | 0 |
| ASCL1 | ASCL1 | P50553 | Achaete-scute homolog 1 | chr12 | GO:0050769 | Not Cancer Driver | No | 33 | 0.14 | 182 | 24 | 0.132 | 0 |
| ASPA | ASPA | P45381 | Aspartoacylase | chr17 | GO:0050769 | Not Cancer Driver | No | 58 | 0.185 | 3 | 0 | 0.0 | 42 |
| ASPM | ASPM | Q8IZT6 | Abnormal spindle-like microcephaly-associated protein | chr1 | GO:0050769 | Not Cancer Driver | No | 554 | 0.159 | 424 | 67 | 0.158 | 0 |
| BAIAP2 | BAIAP2 | Q9UQB8 | Brain-specific angiogenesis inhibitor 1-associated protein 2 | chr17 | GO:0050769 | Not Cancer Driver | No | 85 | 0.154 | 330 | 52 | 0.158 | 0 |
| BDNF_ENST00000439476 | BDNF | P23560 | Brain-derived neurotrophic factor | chr11 | GO:0050769 | Not Cancer Driver | No | 47 | 0.19 | 79 | 19 | 0.241 | 1 |
| BHLHB9 | BHLHB9 | Q6PI77 | Protein BHLHb9 | chrX | GO:0050769 | Not Cancer Driver | No | 88 | 0.161 | 267 | 38 | 0.142 | 0 |
| BIN1 | BIN1 | O00499 | Myc box-dependent-interacting protein 1 | chr2 | GO:0050769 | Not Cancer Driver | No | 65 | 0.11 | 456 | 42 | 0.092 | 5 |
| BMP2 | BMP2 | P12643 | Bone morphogenetic protein 2 | chr20 | GO:0050769 | Not Cancer Driver | No | 73 | 0.184 | 139 | 26 | 0.187 | 0 |
| BMPR2 | BMPR2 | Q13873 | Bone morphogenetic protein receptor type-2 | chr2 | GO:0050769 | Compendium | Yes | 141 | 0.136 | 601 | 70 | 0.116 | 19 |
| CAMK2B | CAMK2B | Q13554 | Calcium/calmodulin-dependent protein kinase type II subunit beta | chr7 | GO:0050769 | Not Cancer Driver | No | 86 | 0.129 | 273 | 28 | 0.103 | 6 |
| CAPRIN1_ENST00000532820 | CAPRIN1 | Q14444 | Caprin-1 | chr11 | GO:0050769 | Not Cancer Driver | No | 84 | 0.118 | 603 | 72 | 0.119 | 0 |
| CDH4 | CDH4 | P55283 | Cadherin-4 | chr20 | GO:0050769 | Not Cancer Driver | No | 266 | 0.29 | 441 | 152 | 0.345 | 0 |
| CDKL3 | CDKL3 | Q8IVW4 | Cyclin-dependent kinase-like 3 | chr5 | GO:0050769 | Not Cancer Driver | No | 68 | 0.115 | 278 | 40 | 0.144 | 0 |
| CDKL5_ENST00000623535 | CDKL5 | O76039 | Cyclin-dependent kinase-like 5 | chrX | GO:0050769 | Not Cancer Driver | No | 165 | 0.172 | 685 | 120 | 0.175 | 18 |
| CLCF1 | CLCF1 | Q9UBD9 | Cardiotrophin-like cytokine factor 1 | chr11 | GO:0050769 | Not Cancer Driver | No | 22 | 0.098 | 42 | 4 | 0.095 | 1 |
| CRABP2_ENST00000368221 | CRABP2 | P29373 | Cellular retinoic acid-binding protein 2 | chr1 | GO:0050769 | Not Cancer Driver | No | 27 | 0.196 | 23 | 6 | 0.261 | 0 |
| CTNNB1_ENST00000643977 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | GO:0050769 | Census, Compendium | Yes | 415 | 0.531 | 288 | 301 | 1.045 | 14 |
| CUL7_ENST00000265348 | CUL7 | Q14999 | Cullin-7 | chr6 | GO:0050769 | Not Cancer Driver | No | 188 | 0.111 | 372 | 41 | 0.11 | 3 |
| CUX2 | CUX2 | O14529 | Homeobox protein cut-like 2 | chr12 | GO:0050769 | Not Cancer Driver | No | 277 | 0.186 | 1201 | 212 | 0.177 | 1 |
| CX3CL1 | CX3CL1 | P78423 | Fractalkine | chr16 | GO:0050769 | Not Cancer Driver | No | 66 | 0.166 | 259 | 44 | 0.17 | 0 |
| CX3CR1_ENST00000542107 | CX3CR1 | P49238 | CX3C chemokine receptor 1 | chr3 | GO:0050769 | Not Cancer Driver | No | 80 | 0.225 | 0 | 0 | 0.0 | 0 |
| CXCL12_ENST00000374429 | CXCL12 | P48061 | Stromal cell-derived factor 1 | chr10 | GO:0050769 | Not Cancer Driver | No | 16 | 0.172 | 0 | 0 | 0.0 | 0 |
| CXCR4_ENST00000241393 | CXCR4 | P61073 | C-X-C chemokine receptor type 4 | chr2 | GO:0050769 | Census, Compendium | Yes | 62 | 0.176 | 5 | 1 | 0.2 | 0 |
| CYFIP1_ENST00000610365 | CYFIP1 | Q7L576 | Cytoplasmic FMR1-interacting protein 1 | chr15 | GO:0050769 | Not Cancer Driver | No | 46 | 0.037 | 96 | 0 | 0.0 | 0 |
| DAG1_ENST00000515359 | DAG1 | Q14118 | Dystroglycan 1 | chr3 | GO:0050769 | Not Cancer Driver | No | 102 | 0.114 | 485 | 61 | 0.126 | 4 |
| DBN1_ENST00000309007 | DBN1 | Q16643 | Drebrin | chr5 | GO:0050769 | Not Cancer Driver | No | 84 | 0.129 | 510 | 73 | 0.143 | 0 |
| DBNL_ENST00000448521 | DBNL | Q9UJU6 | Drebrin-like protein | chr7 | GO:0050769 | Not Cancer Driver | No | 46 | 0.107 | 304 | 31 | 0.102 | 0 |
| DCT_ENST00000377028 | DCT | P40126 | L-dopachrome tautomerase | chr13 | GO:0050769 | Not Cancer Driver | No | 113 | 0.218 | 19 | 4 | 0.211 | 2 |
| DHX36 | DHX36 | Q9H2U1 | ATP-dependent DNA/RNA helicase DHX36 | chr3 | GO:0050769 | Not Cancer Driver | No | 159 | 0.158 | 222 | 39 | 0.176 | 0 |
| DICER1 | DICER1 | Q9UPY3 | Endoribonuclease Dicer | chr14 | GO:0050769 | Census, Compendium | Yes | 264 | 0.137 | 362 | 45 | 0.124 | 4 |
| DISC1_ENST00000439617 | DISC1 | Q9NRI5 | Disrupted in schizophrenia 1 protein | chr1 | GO:0050769 | Not Cancer Driver | No | 132 | 0.155 | 514 | 82 | 0.16 | 0 |
| DMRTA2_ENST00000418121 | DMRTA2 | Q96SC8 | Doublesex- and mab-3-related transcription factor A2 | chr1 | GO:0050769 | Not Cancer Driver | No | 25 | 0.046 | 325 | 19 | 0.058 | 0 |
| DRD2_ENST00000542968 | DRD2 | P14416 | D(2) dopamine receptor | chr11 | GO:0050769 | Not Cancer Driver | No | 127 | 0.287 | 124 | 45 | 0.363 | 0 |
| DSCAM | DSCAM | O60469 | Down syndrome cell adhesion molecule | chr21 | GO:0050769 | Not Cancer Driver | No | 652 | 0.324 | 603 | 201 | 0.333 | 0 |
| E2F1 | E2F1 | Q01094 | Transcription factor E2F1 | chr20 | GO:0050769 | Not Cancer Driver | No | 49 | 0.112 | 272 | 23 | 0.085 | 0 |
| EEF2K | EEF2K | O00418 | Eukaryotic elongation factor 2 kinase | chr16 | GO:0050769 | Not Cancer Driver | No | 104 | 0.143 | 311 | 39 | 0.125 | 0 |
| EFNA5 | EFNA5 | P52803 | Ephrin-A5 | chr5 | GO:0050769 | Not Cancer Driver | No | 34 | 0.149 | 25 | 6 | 0.24 | 0 |
| EGR2 | EGR2 | P11161 | E3 SUMO-protein ligase EGR2 | chr10 | GO:0050769 | Compendium | Yes | 90 | 0.189 | 352 | 59 | 0.168 | 11 |
| EIF4G2_ENST00000640650 | EIF4G2 | P78344 | Eukaryotic translation initiation factor 4 gamma 2 | chr11 | GO:0050769 | Not Cancer Driver | No | 104 | 0.115 | 382 | 43 | 0.113 | 0 |
| ELL3 | ELL3 | Q9HB65 | RNA polymerase II elongation factor ELL3 | chr15 | GO:0050769 | Not Cancer Driver | No | 50 | 0.126 | 186 | 13 | 0.07 | 0 |
| EPHA4_ENST00000409938 | EPHA4 | P54764 | Ephrin type-A receptor 4 | chr2 | GO:0050769 | Not Cancer Driver | No | 182 | 0.185 | 140 | 24 | 0.171 | 0 |
| EPHB2 | EPHB2 | P29323 | Ephrin type-B receptor 2 | chr1 | GO:0050769 | Not Cancer Driver | No | 186 | 0.176 | 119 | 17 | 0.143 | 7 |
| FAIM_ENST00000393035 | FAIM | Q9NVQ4 | Fas apoptotic inhibitory molecule 1 | chr3 | GO:0050769 | Not Cancer Driver | No | 20 | 0.112 | 1 | 0 | 0.0 | 0 |
| FBXO31 | FBXO31 | Q5XUX0 | F-box only protein 31 | chr16 | GO:0050769 | Not Cancer Driver | No | 72 | 0.134 | 231 | 30 | 0.13 | 0 |
| FBXW8 | FBXW8 | Q8N3Y1 | F-box/WD repeat-containing protein 8 | chr12 | GO:0050769 | Not Cancer Driver | No | 68 | 0.114 | 120 | 4 | 0.033 | 0 |
| FN1 | FN1 | P02751 | Fibronectin | chr2 | GO:0050769 | Compendium | Yes | 394 | 0.159 | 1243 | 185 | 0.149 | 8 |
| FOXG1 | FOXG1 | P55316 | Forkhead box protein G1 | chr14 | GO:0050769 | Not Cancer Driver | No | 132 | 0.27 | 322 | 79 | 0.245 | 2 |
| FZD3_ENST00000240093 | FZD3 | Q9NPG1 | Frizzled-3 | chr8 | GO:0050769 | Not Cancer Driver | No | 64 | 0.096 | 141 | 13 | 0.092 | 0 |
| GDI1 | GDI1 | P31150 | Rab GDP dissociation inhibitor alpha | chrX | GO:0050769 | Not Cancer Driver | No | 69 | 0.154 | 34 | 6 | 0.176 | 2 |
| GFAP_ENST00000588735 | GFAP | P14136 | Glial fibrillary acidic protein | chr17 | GO:0050769 | Not Cancer Driver | No | 65 | 0.15 | 288 | 42 | 0.146 | 62 |
| GJC2 | GJC2 | Q5T442 | Gap junction gamma-2 protein | chr1 | GO:0050769 | Not Cancer Driver | No | 33 | 0.075 | 225 | 10 | 0.044 | 6 |
| GLI3 | GLI3 | P10071 | Transcriptional activator GLI3 | chr7 | GO:0050769 | Not Cancer Driver | No | 385 | 0.244 | 1352 | 327 | 0.242 | 7 |
| GOLGA4_ENST00000361924 | GOLGA4 | Q13439 | Golgin subfamily A member 4 | chr3 | GO:0050769 | Not Cancer Driver | No | 231 | 0.104 | 1658 | 162 | 0.098 | 0 |
| GPER1 | GPER1 | Q99527 | G-protein coupled estrogen receptor 1 | chr7 | GO:0050769 | Not Cancer Driver | No | 65 | 0.173 | 13 | 5 | 0.385 | 0 |
| GRM5 | GRM5 | P41594 | Metabotropic glutamate receptor 5 | chr11 | GO:0050769 | Not Cancer Driver | No | 312 | 0.257 | 323 | 51 | 0.158 | 0 |
| GSX2 | GSX2 | Q9BZM3 | GS homeobox 2 | chr4 | GO:0050769 | Not Cancer Driver | No | 44 | 0.145 | 210 | 26 | 0.124 | 1 |
| HAP1_ENST00000310778 | HAP1 | P54257 | Huntingtin-associated protein 1 | chr17 | GO:0050769 | Not Cancer Driver | No | 97 | 0.145 | 454 | 60 | 0.132 | 0 |
| HDAC1 | HDAC1 | Q13547 | Histone deacetylase 1 | chr1 | GO:0050769 | Not Cancer Driver | No | 47 | 0.098 | 135 | 10 | 0.074 | 0 |
| HDAC2 | HDAC2 | Q92769 | Histone deacetylase 2 | chr6 | GO:0050769 | Not Cancer Driver | No | 46 | 0.094 | 145 | 14 | 0.097 | 0 |
| HES1 | HES1 | Q14469 | Transcription factor HES-1 | chr3 | GO:0050769 | Not Cancer Driver | No | 37 | 0.132 | 226 | 32 | 0.142 | 0 |
| HIF1A_ENST00000337138 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | GO:0050769 | Census | Yes | 118 | 0.143 | 435 | 51 | 0.117 | 0 |
| ID2_ENST00000396290 | ID2 | Q02363 | DNA-binding protein inhibitor ID-2 | chr2 | GO:0050769 | Not Cancer Driver | No | 14 | 0.104 | 52 | 7 | 0.135 | 0 |
| IFNG | IFNG | P01579 | Interferon gamma | chr12 | GO:0050769 | Not Cancer Driver | No | 51 | 0.307 | 23 | 6 | 0.261 | 0 |
| IL1B | IL1B | P01584 | Interleukin-1 beta | chr2 | GO:0050769 | Not Cancer Driver | No | 39 | 0.145 | 16 | 3 | 0.188 | 0 |
| IL1RAPL1 | IL1RAPL1 | Q9NZN1 | Interleukin-1 receptor accessory protein-like 1 | chrX | GO:0050769 | Not Cancer Driver | No | 205 | 0.295 | 77 | 19 | 0.247 | 0 |
| IL34 | IL34 | Q6ZMJ4 | Interleukin-34 | chr16 | GO:0050769 | Not Cancer Driver | No | 22 | 0.091 | 42 | 6 | 0.143 | 0 |
| IL6 | IL6 | P05231 | Interleukin-6 | chr7 | GO:0050769 | Not Cancer Driver | No | 35 | 0.165 | 58 | 7 | 0.121 | 0 |
| IL6ST_ENST00000336909 | IL6ST | P40189 | Interleukin-6 receptor subunit beta | chr5 | GO:0050769 | Census, Compendium | Yes | 102 | 0.111 | 315 | 40 | 0.127 | 2 |
| ISLR2_ENST00000565159 | ISLR2 | Q6UXK2 | Immunoglobulin superfamily containing leucine-rich repeat protein 2 | chr15 | GO:0050769 | Not Cancer Driver | No | 128 | 0.172 | 344 | 49 | 0.142 | 0 |
| IST1_ENST00000541571 | IST1 | P53990 | IST1 homolog | chr16 | GO:0050769 | Not Cancer Driver | No | 31 | 0.085 | 185 | 17 | 0.092 | 0 |
| ITPKA | ITPKA | P23677 | Inositol-trisphosphate 3-kinase A | chr15 | GO:0050769 | Not Cancer Driver | No | 28 | 0.061 | 216 | 7 | 0.032 | 0 |
| KDM1A_ENST00000356634 | KDM1A | O60341 | Lysine-specific histone demethylase 1A | chr1 | GO:0050769 | Not Cancer Driver | No | 67 | 0.079 | 291 | 28 | 0.096 | 3 |
| KHDC3L | KHDC3L | Q587J8 | KH domain-containing protein 3 | chr6 | GO:0050769 | Not Cancer Driver | No | 68 | 0.313 | 121 | 43 | 0.355 | 0 |
| KIT | KIT | P10721 | Mast/stem cell growth factor receptor Kit | chr4 | GO:0050769 | Census, Compendium | Yes | 226 | 0.232 | 83 | 33 | 0.398 | 21 |
| L1CAM | L1CAM | P32004 | Neural cell adhesion molecule L1 | chrX | GO:0050769 | Not Cancer Driver | No | 228 | 0.181 | 442 | 75 | 0.17 | 54 |
| LIF | LIF | P15018 | Leukemia inhibitory factor | chr22 | GO:0050769 | Not Cancer Driver | No | 25 | 0.124 | 0 | 0 | 0.0 | 0 |
| LIG4 | LIG4 | P49917 | DNA ligase 4 | chr13 | GO:0050769 | Not Cancer Driver | No | 134 | 0.147 | 63 | 10 | 0.159 | 2 |
| LIMK1 | LIMK1 | P53667 | LIM domain kinase 1 | chr7 | GO:0050769 | Not Cancer Driver | No | 110 | 0.17 | 170 | 30 | 0.176 | 0 |
| LPAR3_ENST00000370611 | LPAR3 | Q9UBY5 | Lysophosphatidic acid receptor 3 | chr1 | GO:0050769 | Not Cancer Driver | No | 65 | 0.184 | 9 | 0 | 0.0 | 0 |
| LRP2 | LRP2 | P98164 | Low-density lipoprotein receptor-related protein 2 | chr2 | GO:0050769 | Not Cancer Driver | No | 998 | 0.214 | 209 | 40 | 0.191 | 1 |
| LRP8 | LRP8 | Q14114 | Low-density lipoprotein receptor-related protein 8 | chr1 | GO:0050769 | Not Cancer Driver | No | 94 | 0.098 | 190 | 24 | 0.126 | 0 |
| LTA | LTA | P01374 | Lymphotoxin-alpha | chr6 | GO:0050769 | Not Cancer Driver | No | 37 | 0.18 | 20 | 5 | 0.25 | 0 |
| LYN | LYN | P07948 | Tyrosine-protein kinase Lyn | chr8 | GO:0050769 | Census | Yes | 95 | 0.186 | 84 | 12 | 0.143 | 0 |
| MACF1_ENST00000372915 | MACF1 | Q9UPN3 | Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 | chr1 | GO:0050769 | Not Cancer Driver | No | 877 | 0.119 | 2826 | 334 | 0.118 | 4 |
| MAG_ENST00000537831 | MAG | P20916 | Myelin-associated glycoprotein | chr19 | GO:0050769 | Not Cancer Driver | No | 118 | 0.188 | 65 | 7 | 0.108 | 1 |
| MAN2A1 | MAN2A1 | Q16706 | Alpha-mannosidase 2 | chr5 | GO:0050769 | Not Cancer Driver | No | 165 | 0.144 | 83 | 9 | 0.108 | 0 |
| MAP1B | MAP1B | P46821 | Microtubule-associated protein 1B | chr5 | GO:0050769 | Not Cancer Driver | No | 332 | 0.135 | 1947 | 278 | 0.143 | 0 |
| MAP3K13_ENST00000424227 | MAP3K13 | O43283 | Mitogen-activated protein kinase kinase kinase 13 | chr3 | GO:0050769 | Census | Yes | 157 | 0.163 | 593 | 91 | 0.153 | 0 |
| MAPT_ENST00000262410 | MAPT | P10636 | Microtubule-associated protein tau | chr17 | GO:0050769 | Not Cancer Driver | No | 128 | 0.169 | 750 | 126 | 0.168 | 18 |
| MDK_ENST00000407067 | MDK | P21741 | Midkine | chr11 | GO:0050769 | Not Cancer Driver | No | 15 | 0.105 | 20 | 2 | 0.1 | 0 |
| MEGF8 | MEGF8 | Q7Z7M0 | Multiple epidermal growth factor-like domains protein 8 | chr19 | GO:0050769 | Not Cancer Driver | No | 363 | 0.128 | 476 | 59 | 0.124 | 3 |
| MME_ENST00000492661 | MME | P08473 | Neprilysin | chr3 | GO:0050769 | Not Cancer Driver | No | 189 | 0.252 | 40 | 17 | 0.425 | 4 |
| MTOR | MTOR | P42345 | Serine/threonine-protein kinase mTOR | chr1 | GO:0050769 | Census, Compendium | Yes | 379 | 0.149 | 296 | 37 | 0.125 | 18 |
| MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | GO:0050769 | Census, Compendium | Yes | 80 | 0.182 | 299 | 46 | 0.154 | 0 |
| NAP1L1 | NAP1L1 | P55209 | Nucleosome assembly protein 1-like 1 | chr12 | GO:0050769 | Not Cancer Driver | No | 47 | 0.12 | 207 | 31 | 0.15 | 0 |
| NDEL1 | NDEL1 | Q9GZM8 | Nuclear distribution protein nudE-like 1 | chr17 | GO:0050769 | Not Cancer Driver | No | 32 | 0.093 | 202 | 16 | 0.079 | 0 |
| NEURL1 | NEURL1 | O76050 | E3 ubiquitin-protein ligase NEURL1 | chr10 | GO:0050769 | Not Cancer Driver | No | 62 | 0.108 | 153 | 11 | 0.072 | 0 |
| NGF | NGF | P01138 | Beta-nerve growth factor | chr1 | GO:0050769 | Not Cancer Driver | No | 66 | 0.274 | 93 | 25 | 0.269 | 1 |
| NKX2-2 | NKX2-2 | O95096 | Homeobox protein Nkx-2.2 | chr20 | GO:0050769 | Not Cancer Driver | No | 84 | 0.308 | 206 | 65 | 0.316 | 0 |
| NKX6-1 | NKX6-1 | P78426 | Homeobox protein Nkx-6.1 | chr4 | GO:0050769 | Not Cancer Driver | No | 38 | 0.104 | 325 | 34 | 0.105 | 0 |
| NKX6-2 | NKX6-2 | Q9C056 | Homeobox protein Nkx-6.2 | chr10 | GO:0050769 | Not Cancer Driver | No | 27 | 0.097 | 137 | 23 | 0.168 | 0 |
| NOTCH1 | NOTCH1 | P46531 | Neurogenic locus notch homolog protein 1 | chr9 | GO:0050769 | Census, Compendium | Yes | 363 | 0.142 | 686 | 87 | 0.127 | 3 |
| NPTN | NPTN | Q9Y639 | Neuroplastin | chr15 | GO:0050769 | Not Cancer Driver | No | 47 | 0.118 | 118 | 9 | 0.076 | 0 |
| NRP1 | NRP1 | O14786 | Neuropilin-1 | chr10 | GO:0050769 | Compendium | Yes | 146 | 0.158 | 211 | 31 | 0.147 | 0 |
| NTN1 | NTN1 | O95631 | Netrin-1 | chr17 | GO:0050769 | Not Cancer Driver | No | 57 | 0.094 | 66 | 4 | 0.061 | 2 |
| NUMBL | NUMBL | Q9Y6R0 | Numb-like protein | chr19 | GO:0050769 | Not Cancer Driver | No | 42 | 0.069 | 467 | 23 | 0.049 | 0 |
| NUMB_ENST00000355058 | NUMB | P49757 | Protein numb homolog | chr14 | GO:0050769 | Not Cancer Driver | No | 70 | 0.108 | 490 | 58 | 0.118 | 0 |
| OBSL1 | OBSL1 | O75147 | Obscurin-like protein 1 | chr2 | GO:0050769 | Not Cancer Driver | No | 233 | 0.123 | 553 | 60 | 0.108 | 0 |
| OLIG2_ENST00000382357 | OLIG2 | Q13516 | Oligodendrocyte transcription factor 2 | chr21 | GO:0050769 | Census | Yes | 37 | 0.115 | 256 | 37 | 0.145 | 0 |
| OPRM1_ENST00000330432 | OPRM1 | P35372 | Mu-type opioid receptor | chr6 | GO:0050769 | Not Cancer Driver | No | 107 | 0.268 | 58 | 27 | 0.466 | 0 |
| OTP | OTP | Q5XKR4 | Homeobox protein orthopedia | chr5 | GO:0050769 | Not Cancer Driver | No | 36 | 0.111 | 278 | 29 | 0.104 | 0 |
| PAFAH1B1 | PAFAH1B1 | P43034 | Platelet-activating factor acetylhydrolase IB subunit beta | chr17 | GO:0050769 | Not Cancer Driver | No | 42 | 0.102 | 82 | 11 | 0.134 | 7 |
| PAK3_ENST00000262836 | PAK3 | O75914 | Serine/threonine-protein kinase PAK 3 | chrX | GO:0050769 | Not Cancer Driver | No | 127 | 0.227 | 286 | 64 | 0.224 | 2 |
| PARP6 | PARP6 | Q2NL67 | Protein mono-ADP-ribosyltransferase PARP6 | chr15 | GO:0050769 | Not Cancer Driver | No | 87 | 0.138 | 67 | 13 | 0.194 | 0 |
| PAX6_ENST00000241001 | PAX6 | P26367 | Paired box protein Pax-6 | chr11 | GO:0050769 | Not Cancer Driver | No | 72 | 0.171 | 337 | 56 | 0.166 | 38 |
| PLAG1_ENST00000429357 | PLAG1 | Q6DJT9 | Zinc finger protein PLAG1 | chr8 | GO:0050769 | Census, Compendium | Yes | 108 | 0.216 | 209 | 48 | 0.23 | 0 |
| POU4F2 | POU4F2 | Q12837 | POU domain, class 4, transcription factor 2 | chr4 | GO:0050769 | Not Cancer Driver | No | 130 | 0.318 | 308 | 87 | 0.282 | 0 |
| PPP1CC_ENST00000335007 | PPP1CC | P36873 | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit | chr12 | GO:0050769 | Not Cancer Driver | No | 26 | 0.08 | 23 | 4 | 0.174 | 0 |
| PRKCH | PRKCH | P24723 | Protein kinase C eta type | chr14 | GO:0050769 | Not Cancer Driver | No | 89 | 0.13 | 92 | 13 | 0.141 | 0 |
| PRKCI | PRKCI | P41743 | Protein kinase C iota type | chr3 | GO:0050769 | Not Cancer Driver | No | 110 | 0.185 | 120 | 16 | 0.133 | 0 |
| PRMT5 | PRMT5 | O14744 | Protein arginine N-methyltransferase 5 | chr14 | GO:0050769 | Not Cancer Driver | No | 83 | 0.13 | 72 | 6 | 0.083 | 0 |
| PRPF19 | PRPF19 | Q9UMS4 | Pre-mRNA-processing factor 19 | chr11 | GO:0050769 | Not Cancer Driver | No | 71 | 0.141 | 109 | 16 | 0.147 | 0 |
| PTN | PTN | P21246 | Pleiotrophin | chr7 | GO:0050769 | Not Cancer Driver | No | 43 | 0.256 | 51 | 11 | 0.216 | 0 |
| PTPRD | PTPRD | P23468 | Receptor-type tyrosine-protein phosphatase delta | chr9 | GO:0050769 | Census, Compendium | Yes | 577 | 0.302 | 747 | 219 | 0.293 | 0 |
| PTPRZ1 | PTPRZ1 | P23471 | Receptor-type tyrosine-protein phosphatase zeta | chr7 | GO:0050769 | Not Cancer Driver | No | 480 | 0.207 | 978 | 216 | 0.221 | 0 |
| RAB11A | RAB11A | P62491 | Ras-related protein Rab-11A | chr15 | GO:0050769 | Not Cancer Driver | No | 31 | 0.144 | 43 | 4 | 0.093 | 0 |
| RAB21 | RAB21 | Q9UL25 | Ras-related protein Rab-21 | chr12 | GO:0050769 | Not Cancer Driver | No | 23 | 0.102 | 59 | 4 | 0.068 | 0 |
| RASSF10 | RASSF10 | A6NK89 | Ras association domain-containing protein 10 | chr11 | GO:0050769 | Not Cancer Driver | No | 11 | 0.022 | 372 | 8 | 0.022 | 0 |
| RELN | RELN | P78509 | Reelin | chr7 | GO:0050769 | Not Cancer Driver | No | 761 | 0.22 | 107 | 19 | 0.178 | 7 |
| RGS14 | RGS14 | O43566 | Regulator of G-protein signaling 14 | chr5 | GO:0050769 | Not Cancer Driver | No | 57 | 0.101 | 309 | 37 | 0.12 | 0 |
| RHEB | RHEB | Q15382 | GTP-binding protein Rheb | chr7 | GO:0050769 | Not Cancer Driver | No | 30 | 0.163 | 0 | 0 | 0.0 | 0 |
| RND2 | RND2 | P52198 | Rho-related GTP-binding protein RhoN | chr17 | GO:0050769 | Not Cancer Driver | No | 19 | 0.084 | 54 | 4 | 0.074 | 0 |
| RNF112 | RNF112 | Q9ULX5 | RING finger protein 112 | chr17 | GO:0050769 | Not Cancer Driver | No | 86 | 0.136 | 168 | 26 | 0.155 | 0 |
| RUFY3_ENST00000226328 | RUFY3 | Q7L099 | Protein RUFY3 | chr4 | GO:0050769 | Not Cancer Driver | No | 75 | 0.16 | 204 | 29 | 0.142 | 0 |
| SEMA4D | SEMA4D | Q92854 | Semaphorin-4D | chr9 | GO:0050769 | Not Cancer Driver | No | 117 | 0.136 | 132 | 15 | 0.114 | 0 |
| SEMA5A | SEMA5A | Q13591 | Semaphorin-5A | chr5 | GO:0050769 | Not Cancer Driver | No | 266 | 0.248 | 23 | 4 | 0.174 | 0 |
| SEMA7A | SEMA7A | O75326 | Semaphorin-7A | chr15 | GO:0050769 | Not Cancer Driver | No | 81 | 0.122 | 150 | 21 | 0.14 | 0 |
| SERPINE2_ENST00000258405 | SERPINE2 | P07093 | Glia-derived nexin | chr2 | GO:0050769 | Not Cancer Driver | No | 62 | 0.156 | 0 | 0 | 0.0 | 0 |
| SERPINF1 | SERPINF1 | P36955 | Pigment epithelium-derived factor | chr17 | GO:0050769 | Not Cancer Driver | No | 51 | 0.122 | 57 | 5 | 0.088 | 0 |
| SHH | SHH | Q15465 | Sonic hedgehog protein | chr7 | GO:0050769 | Not Cancer Driver | No | 56 | 0.121 | 139 | 14 | 0.101 | 81 |
| SHTN1 | SHTN1 | A0MZ66 | Shootin-1 | chr10 | GO:0050769 | Census | Yes | 68 | 0.108 | 470 | 52 | 0.111 | 0 |
| SMARCD3 | SMARCD3 | Q6STE5 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 | chr7 | GO:0050769 | Not Cancer Driver | No | 64 | 0.133 | 213 | 18 | 0.085 | 0 |
| SMO | SMO | Q99835 | Smoothened homolog | chr7 | GO:0050769 | Census, Compendium | Yes | 112 | 0.142 | 241 | 27 | 0.112 | 1 |
| SNW1_ENST00000261531 | SNW1 | Q13573 | SNW domain-containing protein 1 | chr14 | GO:0050769 | Not Cancer Driver | No | 62 | 0.116 | 488 | 56 | 0.115 | 0 |
| SOX10_ENST00000360880 | SOX10 | P56693 | Transcription factor SOX-10 | chr22 | GO:0050769 | Not Cancer Driver | No | 66 | 0.142 | 421 | 62 | 0.147 | 14 |
| SOX11 | SOX11 | P35716 | Transcription factor SOX-11 | chr2 | GO:0050769 | Not Cancer Driver | No | 61 | 0.138 | 368 | 53 | 0.144 | 2 |
| SOX8 | SOX8 | P57073 | Transcription factor SOX-8 | chr16 | GO:0050769 | Not Cancer Driver | No | 43 | 0.096 | 403 | 39 | 0.097 | 0 |
| SPEN | SPEN | Q96T58 | Msx2-interacting protein | chr1 | GO:0050769 | Census, Compendium | Yes | 459 | 0.125 | 3061 | 393 | 0.128 | 0 |
| SPINT1 | SPINT1 | O43278 | Kunitz-type protease inhibitor 1 | chr15 | GO:0050769 | Not Cancer Driver | No | 63 | 0.119 | 75 | 12 | 0.16 | 0 |
| SRF | SRF | P11831 | Serum response factor | chr6 | GO:0050769 | Not Cancer Driver | No | 44 | 0.087 | 443 | 42 | 0.095 | 0 |
| SRRT | SRRT | Q9BXP5 | Serrate RNA effector molecule homolog | chr7 | GO:0050769 | Not Cancer Driver | No | 146 | 0.167 | 595 | 108 | 0.182 | 0 |
| SS18L1 | SS18L1 | O75177 | Calcium-responsive transactivator | chr20 | GO:0050769 | Census | Yes | 53 | 0.134 | 356 | 48 | 0.135 | 0 |
| SS18L2 | SS18L2 | Q9UHA2 | SS18-like protein 2 | chr3 | GO:0050769 | Not Cancer Driver | No | 4 | 0.052 | 7 | 1 | 0.143 | 0 |
| STAU2 | STAU2 | Q9NUL3 | Double-stranded RNA-binding protein Staufen homolog 2 | chr8 | GO:0050769 | Not Cancer Driver | No | 68 | 0.119 | 486 | 54 | 0.111 | 0 |
| SYNJ1 | SYNJ1 | O43426 | Synaptojanin-1 | chr21 | GO:0050769 | Not Cancer Driver | No | 208 | 0.132 | 584 | 76 | 0.13 | 3 |
| TENM4 | TENM4 | Q6N022 | Teneurin-4 | chr11 | GO:0050769 | Not Cancer Driver | No | 492 | 0.178 | 498 | 63 | 0.127 | 3 |
| TGFB1 | TGFB1 | P01137 | Transforming growth factor beta-1 proprotein | chr19 | GO:0050769 | Not Cancer Driver | No | 41 | 0.105 | 41 | 4 | 0.098 | 10 |
| TGM2 | TGM2 | P21980 | Protein-glutamine gamma-glutamyltransferase 2 | chr20 | GO:0050769 | Not Cancer Driver | No | 123 | 0.179 | 107 | 26 | 0.243 | 0 |
| TLR2 | TLR2 | O60603 | Toll-like receptor 2 | chr4 | GO:0050769 | Not Cancer Driver | No | 108 | 0.138 | 0 | 0 | 0.0 | 0 |
| TNF | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0050769 | Not Cancer Driver | No | 24 | 0.103 | 45 | 3 | 0.067 | 0 |
| TNFRSF1B | TNFRSF1B | P20333 | Tumor necrosis factor receptor superfamily member 1B | chr1 | GO:0050769 | Not Cancer Driver | No | 48 | 0.104 | 229 | 28 | 0.122 | 0 |
| TP73 | TP73 | O15350 | Tumor protein p73 | chr1 | GO:0050769 | Not Cancer Driver | No | 82 | 0.129 | 443 | 55 | 0.124 | 0 |
| TRIM32 | TRIM32 | Q13049 | E3 ubiquitin-protein ligase TRIM32 | chr9 | GO:0050769 | Not Cancer Driver | No | 82 | 0.126 | 87 | 10 | 0.115 | 3 |
| TRPC5 | TRPC5 | Q9UL62 | Short transient receptor potential channel 5 | chrX | GO:0050769 | Not Cancer Driver | No | 255 | 0.262 | 148 | 32 | 0.216 | 0 |
| TRPV2 | TRPV2 | Q9Y5S1 | Transient receptor potential cation channel subfamily V member 2 | chr17 | GO:0050769 | Not Cancer Driver | No | 105 | 0.137 | 175 | 23 | 0.131 | 0 |
| TSPO_ENST00000329563 | TSPO | P30536 | Translocator protein | chr22 | GO:0050769 | Not Cancer Driver | No | 5 | 0.03 | 1 | 0 | 0.0 | 0 |
| TTBK1 | TTBK1 | Q5TCY1 | Tau-tubulin kinase 1 | chr6 | GO:0050769 | Not Cancer Driver | No | 193 | 0.146 | 1045 | 154 | 0.147 | 0 |
| TWF2 | TWF2 | Q6IBS0 | Twinfilin-2 | chr3 | GO:0050769 | Not Cancer Driver | No | 34 | 0.097 | 59 | 8 | 0.136 | 0 |
| UFL1 | UFL1 | O94874 | E3 UFM1-protein ligase 1 | chr6 | GO:0050769 | Not Cancer Driver | No | 109 | 0.137 | 141 | 24 | 0.17 | 0 |
| VEGFA_ENST00000523873 | VEGFA | P15692 | Vascular endothelial growth factor A | chr6 | GO:0050769 | Not Cancer Driver | No | 27 | 0.116 | 41 | 7 | 0.171 | 0 |
| VEGFC | VEGFC | P49767 | Vascular endothelial growth factor C | chr4 | GO:0050769 | Not Cancer Driver | No | 128 | 0.305 | 37 | 12 | 0.324 | 0 |
| WDR62_ENST00000270301 | WDR62 | O43379 | WD repeat-containing protein 62 | chr19 | GO:0050769 | Not Cancer Driver | No | 181 | 0.119 | 792 | 100 | 0.126 | 5 |
| WNT2 | WNT2 | P09544 | Protein Wnt-2 | chr7 | GO:0050769 | Not Cancer Driver | No | 85 | 0.236 | 11 | 3 | 0.273 | 0 |
| WNT3 | WNT3 | P56703 | Proto-oncogene Wnt-3 | chr17 | GO:0050769 | Not Cancer Driver | No | 56 | 0.158 | 34 | 7 | 0.206 | 0 |
| WNT3A | WNT3A | P56704 | Protein Wnt-3a | chr1 | GO:0050769 | Not Cancer Driver | No | 77 | 0.219 | 37 | 5 | 0.135 | 0 |
| XRCC2 | XRCC2 | O43543 | DNA repair protein XRCC2 | chr7 | GO:0050769 | Not Cancer Driver | No | 36 | 0.129 | 9 | 1 | 0.111 | 2 |
| XRCC5_ENST00000392132 | XRCC5 | P13010 | X-ray repair cross-complementing protein 5 | chr2 | GO:0050769 | Not Cancer Driver | No | 87 | 0.119 | 118 | 11 | 0.093 | 0 |
| ZFYVE27_ENST00000393677 | ZFYVE27 | Q5T4F4 | Protrudin | chr10 | GO:0050769 | Not Cancer Driver | No | 45 | 0.109 | 140 | 22 | 0.157 | 1 |
| ZNF335 | ZNF335 | Q9H4Z2 | Zinc finger protein 335 | chr20 | GO:0050769 | Not Cancer Driver | No | 185 | 0.138 | 942 | 133 | 0.141 | 1 |