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Total number of protein in "GO:0050714" GO term:  127

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AACS AACS Q86V21 Acetoacetyl-CoA synthetase chr12 GO:0050714 Not Cancer Driver No 92 0.137 16 0 0.0 0
ABAT_ENST00000268251 ABAT P80404 4-aminobutyrate aminotransferase, mitochondrial chr16 GO:0050714 Not Cancer Driver No 84 0.168 28 5 0.179 1
ABCG1 ABCG1 P45844 ATP-binding cassette sub-family G member 1 chr21 GO:0050714 Not Cancer Driver No 104 0.153 32 5 0.156 0
ACHE_ENST00000241069 ACHE P22303 Acetylcholinesterase chr7 GO:0050714 Not Cancer Driver No 81 0.132 64 8 0.125 0
ACSL4_ENST00000469796 ACSL4 O60488 Long-chain-fatty-acid--CoA ligase 4 chrX GO:0050714 Not Cancer Driver No 97 0.136 77 12 0.156 1
ADAM8 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:0050714 Not Cancer Driver No 82 0.1 230 13 0.057 0
ADAM9 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 GO:0050714 Not Cancer Driver No 86 0.105 129 13 0.101 0
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0050714 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADORA2A ADORA2A P29274 Adenosine receptor A2a chr22 GO:0050714 Not Cancer Driver No 61 0.148 93 11 0.118 0
ANG ANG P03950 Angiogenin chr14 GO:0050714 Not Cancer Driver No 19 0.129 36 2 0.056 14
ANKRD1 ANKRD1 Q15327 Ankyrin repeat domain-containing protein 1 chr10 GO:0050714 Not Cancer Driver No 52 0.163 83 13 0.157 0
ANO1 ANO1 Q5XXA6 Anoctamin-1 chr11 GO:0050714 Not Cancer Driver No 155 0.157 168 14 0.083 0
APBB1 APBB1 O00213 Amyloid beta precursor protein binding family B member 1 chr11 GO:0050714 Not Cancer Driver No 105 0.148 399 58 0.145 0
APBB3_ENST00000357560 APBB3 O95704 Amyloid-beta A4 precursor protein-binding family B member 3 chr5 GO:0050714 Not Cancer Driver No 64 0.132 102 13 0.127 0
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 GO:0050714 Not Cancer Driver No 18 0.103 5 0 0.0 0
ATP13A2 ATP13A2 Q9NQ11 Polyamine-transporting ATPase 13A2 chr1 GO:0050714 Not Cancer Driver No 152 0.129 121 10 0.083 9
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0050714 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAIAP3 BAIAP3 O94812 BAI1-associated protein 3 chr16 GO:0050714 Not Cancer Driver No 170 0.143 230 35 0.152 0
BLK BLK P51451 Tyrosine-protein kinase Blk chr8 GO:0050714 Not Cancer Driver No 94 0.186 75 21 0.28 0
BMP6 BMP6 P22004 Bone morphogenetic protein 6 chr6 GO:0050714 Not Cancer Driver No 95 0.185 226 51 0.226 0
C1QTNF12 C1QTNF12 Q5T7M4 Adipolin chr1 GO:0050714 Not Cancer Driver No 13 0.043 105 5 0.048 0
C1QTNF3_ENST00000231338 C1QTNF3 Q9BXJ4 Complement C1q tumor necrosis factor-related protein 3 chr5 GO:0050714 Not Cancer Driver No 42 0.171 73 14 0.192 0
C2CD2L C2CD2L O14523 Phospholipid transfer protein C2CD2L chr11 GO:0050714 Not Cancer Driver No 77 0.109 491 65 0.132 0
CAPN10 CAPN10 Q9HC96 Calpain-10 chr2 GO:0050714 Not Cancer Driver No 87 0.129 52 6 0.115 0
CASR_ENST00000638421 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0050714 Not Cancer Driver No 304 0.282 189 60 0.317 108
CD2AP CD2AP Q9Y5K6 CD2-associated protein chr6 GO:0050714 Not Cancer Driver No 80 0.125 456 60 0.132 0
CD33 CD33 P20138 Myeloid cell surface antigen CD33 chr19 GO:0050714 Not Cancer Driver No 119 0.327 177 50 0.282 0
CD38 CD38 P28907 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 chr4 GO:0050714 Not Cancer Driver No 54 0.18 3 1 0.333 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 GO:0050714 Not Cancer Driver No 287 0.194 145 18 0.124 151
DNM1L_ENST00000549701 DNM1L O00429 Dynamin-1-like protein chr12 GO:0050714 Not Cancer Driver No 67 0.091 212 23 0.108 7
DOC2B DOC2B Q14184 Double C2-like domain-containing protein beta chr17 GO:0050714 Not Cancer Driver No 10 0.024 197 3 0.015 0
EXOC1 EXOC1 Q9NV70 Exocyst complex component 1 chr4 GO:0050714 Not Cancer Driver No 128 0.143 154 22 0.143 0
EXPH5 EXPH5 Q8NEV8 Exophilin-5 chr11 GO:0050714 Not Cancer Driver No 290 0.146 1739 256 0.147 0
EZR EZR P15311 Ezrin chr6 GO:0050714 Census Yes 66 0.113 295 35 0.119 0
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0050714 Not Cancer Driver No 55 0.139 7 2 0.286 0
FFAR1 FFAR1 O14842 Free fatty acid receptor 1 chr19 GO:0050714 Not Cancer Driver No 45 0.15 2 0 0.0 0
FGA FGA P02671 Fibrinogen alpha chain chr4 GO:0050714 Not Cancer Driver No 245 0.283 522 149 0.285 7
FGB FGB P02675 Fibrinogen beta chain chr4 GO:0050714 Not Cancer Driver No 89 0.181 143 29 0.203 7
FGG FGG P02679 Fibrinogen gamma chain chr4 GO:0050714 Not Cancer Driver No 81 0.179 53 8 0.151 8
FRMD4A FRMD4A Q9P2Q2 FERM domain-containing protein 4A chr10 GO:0050714 Not Cancer Driver No 122 0.117 666 72 0.108 0
GCG GCG P01275 Pro-glucagon chr2 GO:0050714 Not Cancer Driver No 49 0.272 82 22 0.268 0
GCK_ENST00000403799 GCK P35557 Hexokinase-4 chr7 GO:0050714 Not Cancer Driver No 88 0.189 73 14 0.192 107
GHRL_ENST00000457360 GHRL Q9UBU3 Appetite-regulating hormone chr3 GO:0050714 Not Cancer Driver No 20 0.171 52 11 0.212 0
GIP GIP P09681 Gastric inhibitory polypeptide chr17 GO:0050714 Not Cancer Driver No 35 0.229 68 16 0.235 0
GIPR GIPR P48546 Gastric inhibitory polypeptide receptor chr19 GO:0050714 Not Cancer Driver No 45 0.097 41 0 0.0 0
GLUD1 GLUD1 P00367 Glutamate dehydrogenase 1, mitochondrial chr10 GO:0050714 Not Cancer Driver No 50 0.09 107 14 0.131 13
GLUL_ENST00000331872 GLUL P15104 Glutamine synthetase chr1 GO:0050714 Not Cancer Driver No 66 0.177 104 21 0.202 2
GOLPH3 GOLPH3 Q9H4A6 Golgi phosphoprotein 3 chr5 GO:0050714 Not Cancer Driver No 41 0.138 72 1 0.014 0
GOLPH3L GOLPH3L Q9H4A5 Golgi phosphoprotein 3-like chr1 GO:0050714 Not Cancer Driver No 24 0.084 81 12 0.148 0
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0050714 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0050714 Not Cancer Driver No 153 0.182 36 9 0.25 0
GPR27 GPR27 Q9NS67 Probable G-protein coupled receptor 27 chr3 GO:0050714 Not Cancer Driver No 26 0.069 23 1 0.043 0
GPR68_ENST00000535815 GPR68 Q15743 Ovarian cancer G-protein coupled receptor 1 chr14 GO:0050714 Not Cancer Driver No 42 0.115 45 1 0.022 1
HCAR2 HCAR2 Q8TDS4 Hydroxycarboxylic acid receptor 2 chr12 GO:0050714 Not Cancer Driver No 78 0.215 43 8 0.186 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0050714 Census Yes 118 0.143 435 51 0.117 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0050714 Not Cancer Driver No 48 0.18 12 1 0.083 0
IER3IP1 IER3IP1 Q9Y5U9 Immediate early response 3-interacting protein 1 chr18 GO:0050714 Not Cancer Driver No 3 0.037 0 0 0.0 2
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0050714 Not Cancer Driver No 45 0.231 87 23 0.264 0
IL13 IL13 P35225 Interleukin-13 chr5 GO:0050714 Not Cancer Driver No 20 0.137 0 0 0.0 0
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0050714 Not Cancer Driver No 30 0.111 35 6 0.171 0
INS INS P01308 Insulin chr11 GO:0050714 Not Cancer Driver No 15 0.136 5 1 0.2 22
IRS2 IRS2 Q9Y4H2 Insulin receptor substrate 2 chr13 GO:0050714 Not Cancer Driver No 69 0.052 1112 57 0.051 0
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0050714 Not Cancer Driver No 85 0.244 180 41 0.228 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0050714 Census, Compendium Yes 136 0.12 59 5 0.085 5
KCNN4 KCNN4 O15554 Intermediate conductance calcium-activated potassium channel protein 4 chr19 GO:0050714 Not Cancer Driver No 60 0.141 31 6 0.194 3
LRRC8A_ENST00000372599 LRRC8A Q8IWT6 Volume-regulated anion channel subunit LRRC8A chr9 GO:0050714 Not Cancer Driver No 105 0.13 32 3 0.094 0
MCU MCU Q8NE86 Calcium uniporter protein, mitochondrial chr10 GO:0050714 Not Cancer Driver No 41 0.117 13 0 0.0 0
MPC2 MPC2 O95563 Mitochondrial pyruvate carrier 2 chr1 GO:0050714 Not Cancer Driver No 13 0.102 0 0 0.0 0
MYH10_ENST00000269243 MYH10 P35580 Myosin-10 chr17 GO:0050714 Not Cancer Driver No 258 0.131 1134 136 0.12 0
MYO18A MYO18A Q92614 Unconventional myosin-XVIIIa chr17 GO:0050714 Not Cancer Driver No 268 0.13 1237 176 0.142 0
MYOM1 MYOM1 P52179 Myomesin-1 chr18 GO:0050714 Not Cancer Driver No 280 0.166 598 122 0.204 0
MYRIP MYRIP Q8NFW9 Rab effector MyRIP chr3 GO:0050714 Not Cancer Driver No 133 0.155 599 95 0.159 0
NKX6-1 NKX6-1 P78426 Homeobox protein Nkx-6.1 chr4 GO:0050714 Not Cancer Driver No 38 0.104 325 34 0.105 0
NLGN2 NLGN2 Q8NFZ4 Neuroligin-2 chr17 GO:0050714 Not Cancer Driver No 91 0.109 300 19 0.063 0
NNAT NNAT Q16517 Neuronatin chr20 GO:0050714 Not Cancer Driver No 9 0.111 8 0 0.0 0
NR0B2 NR0B2 Q15466 Nuclear receptor subfamily 0 group B member 2 chr1 GO:0050714 Not Cancer Driver No 35 0.136 10 2 0.2 0
NR1H2_ENST00000593926 NR1H2 P55055 Oxysterols receptor LXR-beta chr19 GO:0050714 Not Cancer Driver No 56 0.122 179 30 0.168 0
NR1H4 NR1H4 Q96RI1 Bile acid receptor chr12 GO:0050714 Not Cancer Driver No 111 0.228 78 18 0.231 0
OR51E2_ENST00000641638 OR51E2 Q9H255 Olfactory receptor 51E2 chr11 GO:0050714 Not Cancer Driver No 108 0.338 0 0 0.0 0
OSBP OSBP P22059 Oxysterol-binding protein 1 chr11 GO:0050714 Not Cancer Driver No 83 0.103 386 39 0.101 0
OXCT1 OXCT1 P55809 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial chr5 GO:0050714 Not Cancer Driver No 80 0.154 39 5 0.128 11
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0050714 Not Cancer Driver No 51 0.086 14 2 0.143 0
PARD6A PARD6A Q9NPB6 Partitioning defective 6 homolog alpha chr16 GO:0050714 Not Cancer Driver No 25 0.072 177 13 0.073 0
PCK2 PCK2 Q16822 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial chr14 GO:0050714 Not Cancer Driver No 91 0.142 139 13 0.094 0
PCSK1 PCSK1 P29120 Neuroendocrine convertase 1 chr5 GO:0050714 Not Cancer Driver No 139 0.185 336 61 0.182 2
PDX1 PDX1 P52945 Pancreas/duodenum homeobox protein 1 chr13 GO:0050714 Not Cancer Driver No 32 0.113 238 23 0.097 0
PFKFB2 PFKFB2 O60825 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 chr1 GO:0050714 Not Cancer Driver No 68 0.135 97 18 0.186 0
PFKM_ENST00000550924 PFKM P08237 ATP-dependent 6-phosphofructokinase, muscle type chr12 GO:0050714 Not Cancer Driver No 80 0.103 70 8 0.114 9
PLA2G1B PLA2G1B P04054 Phospholipase A2 chr12 GO:0050714 Not Cancer Driver No 17 0.115 0 0 0.0 0
PLA2G6 PLA2G6 O60733 85/88 kDa calcium-independent phospholipase A2 chr22 GO:0050714 Not Cancer Driver No 108 0.134 148 23 0.155 11
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 GO:0050714 Not Cancer Driver No 72 0.163 69 7 0.101 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0050714 Census Yes 72 0.143 44 4 0.091 3
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 GO:0050714 Not Cancer Driver No 11 0.067 24 3 0.125 0
PPID PPID Q08752 Peptidyl-prolyl cis-trans isomerase D chr4 GO:0050714 Not Cancer Driver No 36 0.097 94 9 0.096 0
PPP3CB_ENST00000360663 PPP3CB P16298 Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform chr10 GO:0050714 Not Cancer Driver No 67 0.128 139 18 0.129 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 GO:0050714 Not Cancer Driver No 107 0.145 170 26 0.153 0
PSMD9 PSMD9 O00233 26S proteasome non-ATPase regulatory subunit 9 chr12 GO:0050714 Not Cancer Driver No 22 0.099 173 16 0.092 0
PTPN23 PTPN23 Q9H3S7 Tyrosine-protein phosphatase non-receptor type 23 chr3 GO:0050714 Not Cancer Driver No 147 0.09 796 71 0.089 2
RBP4 RBP4 P02753 Retinol-binding protein 4 chr10 GO:0050714 Not Cancer Driver No 30 0.149 8 1 0.125 4
RFX6 RFX6 Q8HWS3 DNA-binding protein RFX6 chr6 GO:0050714 Not Cancer Driver No 239 0.258 422 94 0.223 3
RPH3AL RPH3AL Q9UNE2 Rab effector Noc2 chr17 GO:0050714 Not Cancer Driver No 40 0.127 162 20 0.123 0
SEC24A SEC24A O95486 Protein transport protein Sec24A chr5 GO:0050714 Not Cancer Driver No 113 0.103 407 49 0.12 0
SERP1_ENST00000239944 SERP1 Q9Y6X1 Stress-associated endoplasmic reticulum protein 1 chr3 GO:0050714 Not Cancer Driver No 6 0.091 30 2 0.067 0
SLC30A8 SLC30A8 Q8IWU4 Zinc transporter 8 chr8 GO:0050714 Not Cancer Driver No 115 0.312 25 9 0.36 0
SOX4 SOX4 Q06945 Transcription factor SOX-4 chr6 GO:0050714 Not Cancer Driver No 28 0.059 400 24 0.06 4
SRI SRI P30626 Sorcin chr7 GO:0050714 Not Cancer Driver No 15 0.076 32 2 0.062 0
STX4 STX4 Q12846 Syntaxin-4 chr16 GO:0050714 Not Cancer Driver No 50 0.168 152 20 0.132 0
SYTL4 SYTL4 Q96C24 Synaptotagmin-like protein 4 chrX GO:0050714 Not Cancer Driver No 116 0.173 267 34 0.127 0
TCF7L2_ENST00000355995 TCF7L2 Q9NQB0 Transcription factor 7-like 2 chr10 GO:0050714 Census, Compendium Yes 122 0.197 516 93 0.18 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0050714 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0050714 Not Cancer Driver No 63 0.152 47 8 0.17 3
TGFB3 TGFB3 P10600 Transforming growth factor beta-3 proprotein chr14 GO:0050714 Not Cancer Driver No 45 0.109 96 14 0.146 1
TLR2 TLR2 O60603 Toll-like receptor 2 chr4 GO:0050714 Not Cancer Driver No 108 0.138 0 0 0.0 0
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0050714 Not Cancer Driver No 292 0.348 0 0 0.0 0
TM7SF3 TM7SF3 Q9NS93 Transmembrane 7 superfamily member 3 chr12 GO:0050714 Not Cancer Driver No 83 0.146 18 4 0.222 0
TMED10 TMED10 P49755 Transmembrane emp24 domain-containing protein 10 chr14 GO:0050714 Not Cancer Driver No 24 0.11 15 3 0.2 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0050714 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRH TRH P20396 Pro-thyrotropin-releasing hormone chr3 GO:0050714 Not Cancer Driver No 45 0.186 217 41 0.189 0
TRPM2_ENST00000397928 TRPM2 O94759 Transient receptor potential cation channel subfamily M member 2 chr21 GO:0050714 Not Cancer Driver No 286 0.19 266 44 0.165 0
TRPM4 TRPM4 Q8TD43 Transient receptor potential cation channel subfamily M member 4 chr19 GO:0050714 Not Cancer Driver No 152 0.125 149 18 0.121 12
TTN_ENST00000615779 TTN Q8WZ42 Titin chr2 GO:0050714 Not Cancer Driver No 7917 0.23 12926 2861 0.221 10
UCN3 UCN3 Q969E3 Urocortin-3 chr10 GO:0050714 Not Cancer Driver No 22 0.137 74 11 0.149 0
UNC13B_ENST00000378495 UNC13B O14795 Protein unc-13 homolog B chr9 GO:0050714 Not Cancer Driver No 214 0.135 448 77 0.172 0
VEGFC VEGFC P49767 Vascular endothelial growth factor C chr4 GO:0050714 Not Cancer Driver No 128 0.305 37 12 0.324 0
VPS35 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 GO:0050714 Not Cancer Driver No 68 0.085 99 9 0.091 1
VSNL1_ENST00000404666 VSNL1 P62760 Visinin-like protein 1 chr2 GO:0050714 Not Cancer Driver No 28 0.147 15 3 0.2 0
WLS_ENST00000262348 WLS Q5T9L3 Protein wntless homolog chr1 GO:0050714 Not Cancer Driver No 71 0.131 14 3 0.214 0