Total number of protein in "GO:0050679" GO term: 189
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACVRL1 | ACVRL1 | P37023 | Serine/threonine-protein kinase receptor R3 | chr12 | GO:0050679 | Not Cancer Driver | No | 93 | 0.185 | 60 | 11 | 0.183 | 82 |
| ADAM17 | ADAM17 | P78536 | Disintegrin and metalloproteinase domain-containing protein 17 | chr2 | GO:0050679 | Not Cancer Driver | No | 80 | 0.097 | 182 | 17 | 0.093 | 0 |
| AGGF1 | AGGF1 | Q8N302 | Angiogenic factor with G patch and FHA domains 1 | chr5 | GO:0050679 | Not Cancer Driver | No | 100 | 0.14 | 582 | 80 | 0.137 | 1 |
| AGTR1_ENST00000349243 | AGTR1 | P30556 | Type-1 angiotensin II receptor | chr3 | GO:0050679 | Not Cancer Driver | No | 95 | 0.265 | 0 | 0 | 0.0 | 1 |
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0050679 | Census, Compendium | Yes | 108 | 0.225 | 158 | 24 | 0.152 | 4 |
| AKT3_ENST00000366539 | AKT3 | Q9Y243 | RAC-gamma serine/threonine-protein kinase | chr1 | GO:0050679 | Census, Compendium | Yes | 92 | 0.192 | 131 | 24 | 0.183 | 3 |
| ANG | ANG | P03950 | Angiogenin | chr14 | GO:0050679 | Not Cancer Driver | No | 19 | 0.129 | 36 | 2 | 0.056 | 14 |
| APELA | APELA | P0DMC3 | Apelin receptor early endogenous ligand | chr4 | GO:0050679 | Not Cancer Driver | No | 1 | 0.019 | 0 | 0 | 0.0 | 0 |
| APLN | APLN | Q9ULZ1 | Apelin | chrX | GO:0050679 | Not Cancer Driver | No | 8 | 0.104 | 51 | 6 | 0.118 | 0 |
| APLNR | APLNR | P35414 | Apelin receptor | chr11 | GO:0050679 | Not Cancer Driver | No | 96 | 0.253 | 29 | 8 | 0.276 | 0 |
| AR | AR | P10275 | Androgen receptor | chrX | GO:0050679 | Census, Compendium | Yes | 196 | 0.213 | 443 | 88 | 0.199 | 169 |
| AREG | AREG | P15514 | Amphiregulin | chr4 | GO:0050679 | Not Cancer Driver | No | 28 | 0.111 | 149 | 20 | 0.134 | 0 |
| ARG1_ENST00000368087 | ARG1 | P05089 | Arginase-1 | chr6 | GO:0050679 | Not Cancer Driver | No | 41 | 0.127 | 83 | 12 | 0.145 | 9 |
| ARNT | ARNT | P27540 | Aryl hydrocarbon receptor nuclear translocator | chr1 | GO:0050679 | Census | Yes | 77 | 0.098 | 511 | 56 | 0.11 | 0 |
| ATP7A | ATP7A | Q04656 | Copper-transporting ATPase 1 | chrX | GO:0050679 | Not Cancer Driver | No | 228 | 0.152 | 171 | 46 | 0.269 | 52 |
| B4GALT1 | B4GALT1 | P15291 | Beta-1,4-galactosyltransferase 1 | chr9 | GO:0050679 | Not Cancer Driver | No | 38 | 0.095 | 129 | 13 | 0.101 | 0 |
| BAD_ENST00000309032 | BAD | Q92934 | Bcl2-associated agonist of cell death | chr11 | GO:0050679 | Not Cancer Driver | No | 14 | 0.083 | 163 | 14 | 0.086 | 0 |
| BMP2 | BMP2 | P12643 | Bone morphogenetic protein 2 | chr20 | GO:0050679 | Not Cancer Driver | No | 73 | 0.184 | 139 | 26 | 0.187 | 0 |
| BMP4 | BMP4 | P12644 | Bone morphogenetic protein 4 | chr14 | GO:0050679 | Not Cancer Driver | No | 86 | 0.211 | 142 | 26 | 0.183 | 5 |
| BMP5 | BMP5 | P22003 | Bone morphogenetic protein 5 | chr6 | GO:0050679 | Census | Yes | 163 | 0.359 | 112 | 62 | 0.554 | 0 |
| BMP6 | BMP6 | P22004 | Bone morphogenetic protein 6 | chr6 | GO:0050679 | Not Cancer Driver | No | 95 | 0.185 | 226 | 51 | 0.226 | 0 |
| BMPR1A | BMPR1A | P36894 | Bone morphogenetic protein receptor type-1A | chr10 | GO:0050679 | Census, Compendium | Yes | 66 | 0.124 | 21 | 0 | 0.0 | 8 |
| BMPR2 | BMPR2 | Q13873 | Bone morphogenetic protein receptor type-2 | chr2 | GO:0050679 | Compendium | Yes | 141 | 0.136 | 601 | 70 | 0.116 | 19 |
| C5AR1 | C5AR1 | P21730 | C5a anaphylatoxin chemotactic receptor 1 | chr19 | GO:0050679 | Not Cancer Driver | No | 71 | 0.203 | 0 | 0 | 0.0 | 0 |
| C5AR2_ENST00000600626 | C5AR2 | Q9P296 | C5a anaphylatoxin chemotactic receptor 2 | chr19 | GO:0050679 | Not Cancer Driver | No | 60 | 0.178 | 11 | 3 | 0.273 | 0 |
| CAV2 | CAV2 | P51636 | Caveolin-2 | chr7 | GO:0050679 | Not Cancer Driver | No | 20 | 0.123 | 5 | 2 | 0.4 | 0 |
| CCL11 | CCL11 | P51671 | Eotaxin | chr17 | GO:0050679 | Not Cancer Driver | No | 18 | 0.186 | 14 | 3 | 0.214 | 0 |
| CCL24_ENST00000222902 | CCL24 | O00175 | C-C motif chemokine 24 | chr7 | GO:0050679 | Not Cancer Driver | No | 25 | 0.21 | 23 | 3 | 0.13 | 0 |
| CCL26_ENST00000005180 | CCL26 | Q9Y258 | C-C motif chemokine 26 | chr7 | GO:0050679 | Not Cancer Driver | No | 9 | 0.096 | 0 | 0 | 0.0 | 0 |
| CCND1 | CCND1 | P24385 | G1/S-specific cyclin-D1 | chr11 | GO:0050679 | Census, Compendium | Yes | 55 | 0.186 | 31 | 25 | 0.806 | 0 |
| CCR3_ENST00000357422 | CCR3 | P51677 | C-C chemokine receptor type 3 | chr3 | GO:0050679 | Not Cancer Driver | No | 84 | 0.237 | 0 | 0 | 0.0 | 0 |
| CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | GO:0050679 | Not Cancer Driver | No | 39 | 0.204 | 23 | 2 | 0.087 | 1 |
| CDH13_ENST00000567109 | CDH13 | P55290 | Cadherin-13 | chr16 | GO:0050679 | Not Cancer Driver | No | 168 | 0.236 | 235 | 59 | 0.251 | 0 |
| CDH3 | CDH3 | P22223 | Cadherin-3 | chr16 | GO:0050679 | Not Cancer Driver | No | 87 | 0.105 | 488 | 52 | 0.107 | 2 |
| CFLAR | CFLAR | O15519 | CASP8 and FADD-like apoptosis regulator | chr2 | GO:0050679 | Not Cancer Driver | No | 40 | 0.083 | 44 | 2 | 0.045 | 0 |
| CLDN1 | CLDN1 | O95832 | Claudin-1 | chr3 | GO:0050679 | Not Cancer Driver | No | 31 | 0.147 | 16 | 3 | 0.188 | 0 |
| CRNN | CRNN | Q9UBG3 | Cornulin | chr1 | GO:0050679 | Not Cancer Driver | No | 109 | 0.22 | 421 | 95 | 0.226 | 1 |
| CTNNB1_ENST00000643977 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | GO:0050679 | Census, Compendium | Yes | 415 | 0.531 | 288 | 301 | 1.045 | 14 |
| CXCL12_ENST00000374429 | CXCL12 | P48061 | Stromal cell-derived factor 1 | chr10 | GO:0050679 | Not Cancer Driver | No | 16 | 0.172 | 0 | 0 | 0.0 | 0 |
| CYBA | CYBA | P13498 | Cytochrome b-245 light chain | chr16 | GO:0050679 | Not Cancer Driver | No | 26 | 0.133 | 66 | 2 | 0.03 | 12 |
| CYP7B1 | CYP7B1 | O75881 | Cytochrome P450 7B1 | chr8 | GO:0050679 | Not Cancer Driver | No | 133 | 0.263 | 0 | 0 | 0.0 | 11 |
| DLX5 | DLX5 | P56178 | Homeobox protein DLX-5 | chr7 | GO:0050679 | Not Cancer Driver | No | 71 | 0.246 | 223 | 57 | 0.256 | 1 |
| ECM1_ENST00000369047 | ECM1 | Q16610 | Extracellular matrix protein 1 | chr1 | GO:0050679 | Not Cancer Driver | No | 91 | 0.169 | 219 | 28 | 0.128 | 1 |
| EGF | EGF | P01133 | Pro-epidermal growth factor | chr4 | GO:0050679 | Not Cancer Driver | No | 184 | 0.152 | 191 | 25 | 0.131 | 1 |
| EGFL7_ENST00000308874 | EGFL7 | Q9UHF1 | Epidermal growth factor-like protein 7 | chr9 | GO:0050679 | Not Cancer Driver | No | 24 | 0.088 | 36 | 2 | 0.056 | 0 |
| EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | GO:0050679 | Census, Compendium | Yes | 444 | 0.367 | 223 | 35 | 0.157 | 1 |
| EGR3 | EGR3 | Q06889 | Early growth response protein 3 | chr8 | GO:0050679 | Not Cancer Driver | No | 60 | 0.155 | 252 | 46 | 0.183 | 0 |
| EMC10 | EMC10 | Q5UCC4 | ER membrane protein complex subunit 10 | chr19 | GO:0050679 | Not Cancer Driver | No | 25 | 0.095 | 109 | 15 | 0.138 | 0 |
| EPGN | EPGN | Q6UW88 | Epigen | chr4 | GO:0050679 | Not Cancer Driver | No | 16 | 0.104 | 0 | 0 | 0.0 | 0 |
| ERBB2 | ERBB2 | P04626 | Receptor tyrosine-protein kinase erbB-2 | chr17 | GO:0050679 | Census, Compendium | Yes | 275 | 0.219 | 314 | 41 | 0.131 | 1 |
| ESRP2_ENST00000565858 | ESRP2 | Q9H6T0 | Epithelial splicing regulatory protein 2 | chr16 | GO:0050679 | Not Cancer Driver | No | 79 | 0.109 | 145 | 12 | 0.083 | 0 |
| EYA1_ENST00000647540 | EYA1 | Q99502 | Eyes absent homolog 1 | chr8 | GO:0050679 | Not Cancer Driver | No | 168 | 0.284 | 341 | 99 | 0.29 | 15 |
| F3 | F3 | P13726 | Tissue factor | chr1 | GO:0050679 | Not Cancer Driver | No | 28 | 0.095 | 61 | 7 | 0.115 | 0 |
| FGF10 | FGF10 | O15520 | Fibroblast growth factor 10 | chr5 | GO:0050679 | Not Cancer Driver | No | 56 | 0.269 | 34 | 11 | 0.324 | 2 |
| FGF1_ENST00000612258 | FGF1 | P05230 | Fibroblast growth factor 1 | chr5 | GO:0050679 | Not Cancer Driver | No | 30 | 0.194 | 29 | 2 | 0.069 | 0 |
| FGF2_ENST00000614010 | FGF2 | P09038 | Fibroblast growth factor 2 | chr4 | GO:0050679 | Not Cancer Driver | No | 18 | 0.062 | 183 | 5 | 0.027 | 0 |
| FGF7 | FGF7 | P21781 | Fibroblast growth factor 7 | chr15 | GO:0050679 | Not Cancer Driver | No | 38 | 0.196 | 22 | 4 | 0.182 | 0 |
| FGF9 | FGF9 | P31371 | Fibroblast growth factor 9 | chr13 | GO:0050679 | Not Cancer Driver | No | 41 | 0.197 | 43 | 10 | 0.233 | 1 |
| FGFBP1 | FGFBP1 | Q14512 | Fibroblast growth factor-binding protein 1 | chr4 | GO:0050679 | Not Cancer Driver | No | 28 | 0.12 | 81 | 8 | 0.099 | 0 |
| FGFR1_ENST00000447712 | FGFR1 | P11362 | Fibroblast growth factor receptor 1 | chr8 | GO:0050679 | Census, Compendium | Yes | 152 | 0.185 | 230 | 43 | 0.187 | 74 |
| FGFR2_ENST00000358487 | FGFR2 | P21802 | Fibroblast growth factor receptor 2 | chr10 | GO:0050679 | Census, Compendium | Yes | 238 | 0.29 | 228 | 44 | 0.193 | 72 |
| FLT4 | FLT4 | P35916 | Vascular endothelial growth factor receptor 3 | chr5 | GO:0050679 | Census, Compendium | Yes | 253 | 0.186 | 259 | 41 | 0.158 | 13 |
| FOXE3 | FOXE3 | Q13461 | Forkhead box protein E3 | chr1 | GO:0050679 | Not Cancer Driver | No | 12 | 0.038 | 186 | 4 | 0.022 | 6 |
| FZD7 | FZD7 | O75084 | Frizzled-7 | chr2 | GO:0050679 | Not Cancer Driver | No | 90 | 0.157 | 22 | 2 | 0.091 | 0 |
| GATA2_ENST00000487848 | GATA2 | P23769 | Endothelial transcription factor GATA-2 | chr3 | GO:0050679 | Census, Compendium | Yes | 72 | 0.15 | 370 | 49 | 0.132 | 6 |
| GHRL_ENST00000457360 | GHRL | Q9UBU3 | Appetite-regulating hormone | chr3 | GO:0050679 | Not Cancer Driver | No | 20 | 0.171 | 52 | 11 | 0.212 | 0 |
| GHSR | GHSR | Q92847 | Growth hormone secretagogue receptor type 1 | chr3 | GO:0050679 | Not Cancer Driver | No | 85 | 0.232 | 4 | 0 | 0.0 | 2 |
| GLUL_ENST00000331872 | GLUL | P15104 | Glutamine synthetase | chr1 | GO:0050679 | Not Cancer Driver | No | 66 | 0.177 | 104 | 21 | 0.202 | 2 |
| GPBAR1_ENST00000521462 | GPBAR1 | Q8TDU6 | G-protein coupled bile acid receptor 1 | chr2 | GO:0050679 | Not Cancer Driver | No | 30 | 0.091 | 22 | 4 | 0.182 | 0 |
| GRN | GRN | P28799 | Progranulin | chr17 | GO:0050679 | Not Cancer Driver | No | 76 | 0.128 | 29 | 6 | 0.207 | 1 |
| HAS2 | HAS2 | Q92819 | Hyaluronan synthase 2 | chr8 | GO:0050679 | Not Cancer Driver | No | 100 | 0.181 | 17 | 7 | 0.412 | 0 |
| HIF1A_ENST00000337138 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | GO:0050679 | Census | Yes | 118 | 0.143 | 435 | 51 | 0.117 | 0 |
| HMGB1_ENST00000405805 | HMGB1 | P09429 | High mobility group protein B1 | chr13 | GO:0050679 | Not Cancer Driver | No | 25 | 0.116 | 203 | 20 | 0.099 | 0 |
| HMGB2 | HMGB2 | P26583 | High mobility group protein B2 | chr4 | GO:0050679 | Not Cancer Driver | No | 38 | 0.182 | 207 | 38 | 0.184 | 0 |
| HMOX1 | HMOX1 | P09601 | Heme oxygenase 1 | chr22 | GO:0050679 | Not Cancer Driver | No | 46 | 0.16 | 81 | 13 | 0.16 | 0 |
| HPN_ENST00000392226 | HPN | P05981 | Serine protease hepsin | chr19 | GO:0050679 | Not Cancer Driver | No | 60 | 0.144 | 12 | 0 | 0.0 | 0 |
| HRAS | HRAS | P01112 | GTPase HRas | chr11 | GO:0050679 | Census, Compendium | Yes | 107 | 0.566 | 16 | 4 | 0.25 | 18 |
| HTR2B | HTR2B | P41595 | 5-hydroxytryptamine receptor 2B | chr2 | GO:0050679 | Not Cancer Driver | No | 41 | 0.085 | 23 | 2 | 0.087 | 0 |
| HTRA1 | HTRA1 | Q92743 | Serine protease HTRA1 | chr10 | GO:0050679 | Not Cancer Driver | No | 77 | 0.16 | 40 | 9 | 0.225 | 11 |
| HYAL1_ENST00000395144 | HYAL1 | Q12794 | Hyaluronidase-1 | chr3 | GO:0050679 | Not Cancer Driver | No | 47 | 0.108 | 9 | 0 | 0.0 | 1 |
| ID1 | ID1 | P41134 | DNA-binding protein inhibitor ID-1 | chr20 | GO:0050679 | Not Cancer Driver | No | 20 | 0.129 | 17 | 6 | 0.353 | 0 |
| IGF1_ENST00000307046 | IGF1 | P05019 | Insulin-like growth factor I | chr12 | GO:0050679 | Not Cancer Driver | No | 45 | 0.231 | 87 | 23 | 0.264 | 0 |
| IGF2_ENST00000641326 | IGF2 | P01344 | Insulin-like growth factor II | chr11 | GO:0050679 | Not Cancer Driver | No | 39 | 0.217 | 44 | 12 | 0.273 | 0 |
| IHH | IHH | Q14623 | Indian hedgehog protein | chr2 | GO:0050679 | Not Cancer Driver | No | 58 | 0.141 | 111 | 15 | 0.135 | 6 |
| IL10 | IL10 | P22301 | Interleukin-10 | chr1 | GO:0050679 | Not Cancer Driver | No | 19 | 0.107 | 23 | 1 | 0.043 | 0 |
| IQGAP3 | IQGAP3 | Q86VI3 | Ras GTPase-activating-like protein IQGAP3 | chr1 | GO:0050679 | Not Cancer Driver | No | 233 | 0.143 | 257 | 36 | 0.14 | 0 |
| ITGA4 | ITGA4 | P13612 | Integrin alpha-4 | chr2 | GO:0050679 | Not Cancer Driver | No | 254 | 0.246 | 97 | 27 | 0.278 | 0 |
| ITGB3 | ITGB3 | P05106 | Integrin beta-3 | chr17 | GO:0050679 | Not Cancer Driver | No | 124 | 0.157 | 66 | 5 | 0.076 | 30 |
| JAML | JAML | Q86YT9 | Junctional adhesion molecule-like | chr11 | GO:0050679 | Not Cancer Driver | No | 72 | 0.183 | 68 | 11 | 0.162 | 0 |
| JCAD | JCAD | Q9P266 | Junctional protein associated with coronary artery disease | chr10 | GO:0050679 | Not Cancer Driver | No | 291 | 0.214 | 1337 | 290 | 0.217 | 0 |
| JUN | JUN | P05412 | Transcription factor Jun | chr1 | GO:0050679 | Census | Yes | 35 | 0.106 | 281 | 25 | 0.089 | 0 |
| KDM5B_ENST00000367265 | KDM5B | Q9UGL1 | Lysine-specific demethylase 5B | chr1 | GO:0050679 | Not Cancer Driver | No | 219 | 0.142 | 388 | 58 | 0.149 | 0 |
| KDR | KDR | P35968 | Vascular endothelial growth factor receptor 2 | chr4 | GO:0050679 | Census, Compendium | Yes | 357 | 0.263 | 275 | 55 | 0.2 | 2 |
| LACRT | LACRT | Q9GZZ8 | Extracellular glycoprotein lacritin | chr12 | GO:0050679 | Not Cancer Driver | No | 38 | 0.275 | 90 | 27 | 0.3 | 0 |
| LAMB1 | LAMB1 | P07942 | Laminin subunit beta-1 | chr7 | GO:0050679 | Not Cancer Driver | No | 240 | 0.134 | 418 | 50 | 0.12 | 0 |
| LAMC1 | LAMC1 | P11047 | Laminin subunit gamma-1 | chr1 | GO:0050679 | Not Cancer Driver | No | 232 | 0.144 | 562 | 94 | 0.167 | 0 |
| LRG1 | LRG1 | P02750 | Leucine-rich alpha-2-glycoprotein | chr19 | GO:0050679 | Not Cancer Driver | No | 63 | 0.182 | 29 | 8 | 0.276 | 0 |
| MAP2K5 | MAP2K5 | Q13163 | Dual specificity mitogen-activated protein kinase kinase 5 | chr15 | GO:0050679 | Not Cancer Driver | No | 40 | 0.089 | 85 | 10 | 0.118 | 0 |
| MDK_ENST00000407067 | MDK | P21741 | Midkine | chr11 | GO:0050679 | Not Cancer Driver | No | 15 | 0.105 | 20 | 2 | 0.1 | 0 |
| MED1 | MED1 | Q15648 | Mediator of RNA polymerase II transcription subunit 1 | chr17 | GO:0050679 | Not Cancer Driver | No | 162 | 0.102 | 1104 | 117 | 0.106 | 0 |
| MMP12 | MMP12 | P39900 | Macrophage metalloelastase | chr11 | GO:0050679 | Not Cancer Driver | No | 100 | 0.213 | 29 | 5 | 0.172 | 0 |
| MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | GO:0050679 | Census, Compendium | Yes | 80 | 0.182 | 299 | 46 | 0.154 | 0 |
| MYDGF | MYDGF | Q969H8 | Myeloid-derived growth factor | chr19 | GO:0050679 | Not Cancer Driver | No | 23 | 0.133 | 26 | 4 | 0.154 | 0 |
| NF1 | NF1 | P21359 | Neurofibromin | chr17 | GO:0050679 | Census, Compendium | Yes | 375 | 0.132 | 406 | 47 | 0.116 | 85 |
| NME1_ENST00000393196 | NME1 | P15531 | Nucleoside diphosphate kinase A | chr17 | GO:0050679 | Not Cancer Driver | No | 11 | 0.072 | 10 | 0 | 0.0 | 0 |
| NME2 | NME2 | P22392 | Nucleoside diphosphate kinase B | chr17 | GO:0050679 | Not Cancer Driver | No | 13 | 0.086 | 11 | 1 | 0.091 | 0 |
| NOD2 | NOD2 | Q9HC29 | Nucleotide-binding oligomerization domain-containing protein 2 | chr16 | GO:0050679 | Not Cancer Driver | No | 169 | 0.163 | 40 | 4 | 0.1 | 15 |
| NODAL | NODAL | Q96S42 | Nodal homolog | chr10 | GO:0050679 | Not Cancer Driver | No | 40 | 0.115 | 34 | 8 | 0.235 | 4 |
| NOG | NOG | Q13253 | Noggin | chr17 | GO:0050679 | Not Cancer Driver | No | 22 | 0.095 | 86 | 9 | 0.105 | 20 |
| NOTCH1 | NOTCH1 | P46531 | Neurogenic locus notch homolog protein 1 | chr9 | GO:0050679 | Census, Compendium | Yes | 363 | 0.142 | 686 | 87 | 0.127 | 3 |
| NOTCH2 | NOTCH2 | Q04721 | Neurogenic locus notch homolog protein 2 | chr1 | GO:0050679 | Census, Compendium | Yes | 282 | 0.114 | 630 | 77 | 0.122 | 1 |
| NR4A1_ENST00000394825 | NR4A1 | P22736 | Nuclear receptor subfamily 4 group A member 1 | chr12 | GO:0050679 | Not Cancer Driver | No | 62 | 0.104 | 252 | 24 | 0.095 | 0 |
| NR4A3_ENST00000395097 | NR4A3 | Q92570 | Nuclear receptor subfamily 4 group A member 3 | chr9 | GO:0050679 | Census | Yes | 83 | 0.133 | 298 | 37 | 0.124 | 0 |
| NRARP | NRARP | Q7Z6K4 | Notch-regulated ankyrin repeat-containing protein | chr9 | GO:0050679 | Not Cancer Driver | No | 9 | 0.079 | 11 | 1 | 0.091 | 0 |
| NRAS | NRAS | P01111 | GTPase NRas | chr1 | GO:0050679 | Census, Compendium | Yes | 284 | 1.503 | 10 | 0 | 0.0 | 14 |
| NRP1 | NRP1 | O14786 | Neuropilin-1 | chr10 | GO:0050679 | Compendium | Yes | 146 | 0.158 | 211 | 31 | 0.147 | 0 |
| NRP2 | NRP2 | O60462 | Neuropilin-2 | chr2 | GO:0050679 | Not Cancer Driver | No | 161 | 0.173 | 207 | 45 | 0.217 | 0 |
| ODAM | ODAM | A1E959 | Odontogenic ameloblast-associated protein | chr4 | GO:0050679 | Not Cancer Driver | No | 51 | 0.183 | 140 | 18 | 0.129 | 0 |
| OSR1 | OSR1 | Q8TAX0 | Protein odd-skipped-related 1 | chr2 | GO:0050679 | Not Cancer Driver | No | 57 | 0.214 | 67 | 17 | 0.254 | 0 |
| OSR2_ENST00000522510 | OSR2 | Q8N2R0 | Protein odd-skipped-related 2 | chr8 | GO:0050679 | Not Cancer Driver | No | 59 | 0.189 | 66 | 13 | 0.197 | 0 |
| PAX2_ENST00000428433 | PAX2 | Q02962 | Paired box protein Pax-2 | chr10 | GO:0050679 | Not Cancer Driver | No | 62 | 0.149 | 296 | 48 | 0.162 | 23 |
| PDCD6 | PDCD6 | O75340 | Programmed cell death protein 6 | chr5 | GO:0050679 | Not Cancer Driver | No | 21 | 0.11 | 24 | 1 | 0.042 | 0 |
| PDCL3 | PDCL3 | Q9H2J4 | Phosducin-like protein 3 | chr2 | GO:0050679 | Not Cancer Driver | No | 48 | 0.201 | 73 | 13 | 0.178 | 0 |
| PDGFB | PDGFB | P01127 | Platelet-derived growth factor subunit B | chr22 | GO:0050679 | Census | Yes | 37 | 0.154 | 99 | 22 | 0.222 | 2 |
| PDPK1 | PDPK1 | O15530 | 3-phosphoinositide-dependent protein kinase 1 | chr16 | GO:0050679 | Not Cancer Driver | No | 33 | 0.059 | 121 | 12 | 0.099 | 0 |
| PGF_ENST00000405431 | PGF | P49763 | Placenta growth factor | chr14 | GO:0050679 | Not Cancer Driver | No | 30 | 0.136 | 72 | 10 | 0.139 | 0 |
| PIK3CD | PIK3CD | O00329 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | chr1 | GO:0050679 | Not Cancer Driver | No | 140 | 0.134 | 60 | 13 | 0.217 | 1 |
| PKHD1 | PKHD1 | P08F94 | Fibrocystin | chr6 | GO:0050679 | Not Cancer Driver | No | 778 | 0.191 | 413 | 81 | 0.196 | 93 |
| PLCG1_ENST00000373271 | PLCG1 | P19174 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | chr20 | GO:0050679 | Census, Compendium | Yes | 158 | 0.122 | 186 | 21 | 0.113 | 0 |
| PLXNB3_ENST00000361971 | PLXNB3 | Q9ULL4 | Plexin-B3 | chrX | GO:0050679 | Not Cancer Driver | No | 217 | 0.114 | 358 | 37 | 0.103 | 0 |
| PPP1R16B | PPP1R16B | Q96T49 | Protein phosphatase 1 regulatory inhibitor subunit 16B | chr20 | GO:0050679 | Not Cancer Driver | No | 132 | 0.233 | 220 | 66 | 0.3 | 0 |
| PRKCA | PRKCA | P17252 | Protein kinase C alpha type | chr17 | GO:0050679 | Not Cancer Driver | No | 94 | 0.14 | 154 | 22 | 0.143 | 0 |
| PRKD1_ENST00000616995 | PRKD1 | Q15139 | Serine/threonine-protein kinase D1 | chr14 | GO:0050679 | Census | Yes | 201 | 0.22 | 189 | 33 | 0.175 | 2 |
| PRKD2_ENST00000291281 | PRKD2 | Q9BZL6 | Serine/threonine-protein kinase D2 | chr19 | GO:0050679 | Compendium | Yes | 118 | 0.134 | 246 | 34 | 0.138 | 0 |
| PROX1 | PROX1 | Q92786 | Prospero homeobox protein 1 | chr1 | GO:0050679 | Not Cancer Driver | No | 182 | 0.247 | 537 | 141 | 0.263 | 0 |
| PTN | PTN | P21246 | Pleiotrophin | chr7 | GO:0050679 | Not Cancer Driver | No | 43 | 0.256 | 51 | 11 | 0.216 | 0 |
| PTPRN | PTPRN | Q16849 | Receptor-type tyrosine-protein phosphatase-like N | chr2 | GO:0050679 | Not Cancer Driver | No | 142 | 0.145 | 498 | 73 | 0.147 | 0 |
| REG3A_ENST00000305165 | REG3A | Q06141 | Regenerating islet-derived protein 3-alpha | chr2 | GO:0050679 | Not Cancer Driver | No | 93 | 0.531 | 19 | 10 | 0.526 | 0 |
| REG3G | REG3G | Q6UW15 | Regenerating islet-derived protein 3-gamma | chr2 | GO:0050679 | Not Cancer Driver | No | 81 | 0.463 | 17 | 4 | 0.235 | 0 |
| RPTOR | RPTOR | Q8N122 | Regulatory-associated protein of mTOR | chr17 | GO:0050679 | Not Cancer Driver | No | 176 | 0.132 | 241 | 21 | 0.087 | 0 |
| RREB1_ENST00000349384 | RREB1 | Q92766 | Ras-responsive element-binding protein 1 | chr6 | GO:0050679 | Not Cancer Driver | No | 213 | 0.126 | 1152 | 144 | 0.125 | 0 |
| RTN4 | RTN4 | Q9NQC3 | Reticulon-4 | chr2 | GO:0050679 | Not Cancer Driver | No | 121 | 0.102 | 866 | 82 | 0.095 | 0 |
| SCG2 | SCG2 | P13521 | Secretogranin-2 | chr2 | GO:0050679 | Not Cancer Driver | No | 116 | 0.188 | 531 | 103 | 0.194 | 0 |
| SCN5A_ENST00000333535 | SCN5A | Q14524 | Sodium channel protein type 5 subunit alpha | chr3 | GO:0050679 | Not Cancer Driver | No | 491 | 0.244 | 550 | 144 | 0.262 | 190 |
| SEMA5A | SEMA5A | Q13591 | Semaphorin-5A | chr5 | GO:0050679 | Not Cancer Driver | No | 266 | 0.248 | 23 | 4 | 0.174 | 0 |
| SFRP1 | SFRP1 | Q8N474 | Secreted frizzled-related protein 1 | chr8 | GO:0050679 | Not Cancer Driver | No | 40 | 0.127 | 39 | 7 | 0.179 | 0 |
| SHH | SHH | Q15465 | Sonic hedgehog protein | chr7 | GO:0050679 | Not Cancer Driver | No | 56 | 0.121 | 139 | 14 | 0.101 | 81 |
| SIRT1 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | GO:0050679 | Not Cancer Driver | No | 70 | 0.094 | 435 | 31 | 0.071 | 0 |
| SIRT6 | SIRT6 | Q8N6T7 | NAD-dependent protein deacylase sirtuin-6 | chr19 | GO:0050679 | Not Cancer Driver | No | 33 | 0.093 | 164 | 12 | 0.073 | 0 |
| SMO | SMO | Q99835 | Smoothened homolog | chr7 | GO:0050679 | Census, Compendium | Yes | 112 | 0.142 | 241 | 27 | 0.112 | 1 |
| SOX11 | SOX11 | P35716 | Transcription factor SOX-11 | chr2 | GO:0050679 | Not Cancer Driver | No | 61 | 0.138 | 368 | 53 | 0.144 | 2 |
| SOX9 | SOX9 | P48436 | Transcription factor SOX-9 | chr17 | GO:0050679 | Compendium | Yes | 86 | 0.169 | 495 | 82 | 0.166 | 18 |
| SP1 | SP1 | P08047 | Transcription factor Sp1 | chr12 | GO:0050679 | Not Cancer Driver | No | 96 | 0.122 | 599 | 71 | 0.119 | 0 |
| SPINK1 | SPINK1 | P00995 | Serine protease inhibitor Kazal-type 1 | chr5 | GO:0050679 | Not Cancer Driver | No | 14 | 0.177 | 0 | 0 | 0.0 | 3 |
| SRSF6 | SRSF6 | Q13247 | Serine/arginine-rich splicing factor 6 | chr20 | GO:0050679 | Not Cancer Driver | No | 69 | 0.201 | 259 | 49 | 0.189 | 0 |
| STAT3 | STAT3 | P40763 | Signal transducer and activator of transcription 3 | chr17 | GO:0050679 | Census, Compendium | Yes | 110 | 0.143 | 152 | 15 | 0.099 | 19 |
| STAT5A_ENST00000590949 | STAT5A | P42229 | Signal transducer and activator of transcription 5A | chr17 | GO:0050679 | Not Cancer Driver | No | 89 | 0.112 | 125 | 14 | 0.112 | 0 |
| STOX1_ENST00000399169 | STOX1 | Q6ZVD7 | Storkhead-box protein 1 | chr10 | GO:0050679 | Not Cancer Driver | No | 121 | 0.122 | 659 | 83 | 0.126 | 2 |
| STXBP4 | STXBP4 | Q6ZWJ1 | Syntaxin-binding protein 4 | chr17 | GO:0050679 | Not Cancer Driver | No | 78 | 0.141 | 211 | 24 | 0.114 | 0 |
| TACR1 | TACR1 | P25103 | Substance-P receptor | chr2 | GO:0050679 | Not Cancer Driver | No | 69 | 0.17 | 28 | 2 | 0.071 | 0 |
| TBX1_ENST00000329705 | TBX1 | O43435 | T-box transcription factor TBX1 | chr22 | GO:0050679 | Not Cancer Driver | No | 35 | 0.088 | 197 | 12 | 0.061 | 4 |
| TCF7L2_ENST00000355995 | TCF7L2 | Q9NQB0 | Transcription factor 7-like 2 | chr10 | GO:0050679 | Census, Compendium | Yes | 122 | 0.197 | 516 | 93 | 0.18 | 0 |
| TEK | TEK | Q02763 | Angiopoietin-1 receptor | chr9 | GO:0050679 | Not Cancer Driver | No | 219 | 0.195 | 126 | 22 | 0.175 | 10 |
| TGFA_ENST00000295400 | TGFA | P01135 | Protransforming growth factor alpha | chr2 | GO:0050679 | Not Cancer Driver | No | 20 | 0.125 | 0 | 0 | 0.0 | 0 |
| TGFBR1_ENST00000374994 | TGFBR1 | P36897 | TGF-beta receptor type-1 | chr9 | GO:0050679 | Not Cancer Driver | No | 86 | 0.171 | 23 | 3 | 0.13 | 15 |
| TGM1 | TGM1 | P22735 | Protein-glutamine gamma-glutamyltransferase K | chr14 | GO:0050679 | Not Cancer Driver | No | 118 | 0.144 | 230 | 37 | 0.161 | 65 |
| THBS4 | THBS4 | P35443 | Thrombospondin-4 | chr5 | GO:0050679 | Not Cancer Driver | No | 137 | 0.143 | 281 | 40 | 0.142 | 0 |
| TNF | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0050679 | Not Cancer Driver | No | 24 | 0.103 | 45 | 3 | 0.067 | 0 |
| TNFAIP3 | TNFAIP3 | P21580 | Tumor necrosis factor alpha-induced protein 3 | chr6 | GO:0050679 | Census, Compendium | Yes | 98 | 0.124 | 231 | 33 | 0.143 | 1 |
| TNFSF12 | TNFSF12 | O43508 | Tumor necrosis factor ligand superfamily member 12 | chr17 | GO:0050679 | Not Cancer Driver | No | 28 | 0.112 | 109 | 8 | 0.073 | 0 |
| TP63 | TP63 | Q9H3D4 | Tumor protein 63 | chr3 | GO:0050679 | Census, Compendium | Yes | 229 | 0.337 | 398 | 143 | 0.359 | 28 |
| TWIST1 | TWIST1 | Q15672 | Twist-related protein 1 | chr7 | GO:0050679 | Not Cancer Driver | No | 23 | 0.114 | 132 | 11 | 0.083 | 7 |
| VASH2 | VASH2 | Q86V25 | Tubulinyl-Tyr carboxypeptidase 2 | chr1 | GO:0050679 | Not Cancer Driver | No | 32 | 0.09 | 106 | 9 | 0.085 | 0 |
| VEGFA_ENST00000523873 | VEGFA | P15692 | Vascular endothelial growth factor A | chr6 | GO:0050679 | Not Cancer Driver | No | 27 | 0.116 | 41 | 7 | 0.171 | 0 |
| VEGFB | VEGFB | P49765 | Vascular endothelial growth factor B | chr11 | GO:0050679 | Not Cancer Driver | No | 25 | 0.121 | 125 | 22 | 0.176 | 0 |
| VEGFC | VEGFC | P49767 | Vascular endothelial growth factor C | chr4 | GO:0050679 | Not Cancer Driver | No | 128 | 0.305 | 37 | 12 | 0.324 | 0 |
| VEGFD | VEGFD | O43915 | Vascular endothelial growth factor D | chrX | GO:0050679 | Not Cancer Driver | No | 59 | 0.167 | 33 | 6 | 0.182 | 0 |
| VIP | VIP | P01282 | VIP peptides | chr6 | GO:0050679 | Not Cancer Driver | No | 58 | 0.341 | 77 | 25 | 0.325 | 0 |
| WDR48 | WDR48 | Q8TAF3 | WD repeat-containing protein 48 | chr3 | GO:0050679 | Not Cancer Driver | No | 61 | 0.09 | 125 | 19 | 0.152 | 0 |
| WNT2 | WNT2 | P09544 | Protein Wnt-2 | chr7 | GO:0050679 | Not Cancer Driver | No | 85 | 0.236 | 11 | 3 | 0.273 | 0 |
| WNT3A | WNT3A | P56704 | Protein Wnt-3a | chr1 | GO:0050679 | Not Cancer Driver | No | 77 | 0.219 | 37 | 5 | 0.135 | 0 |
| WNT5A_ENST00000474267 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:0050679 | Not Cancer Driver | No | 66 | 0.174 | 0 | 0 | 0.0 | 2 |
| WNT7A | WNT7A | O00755 | Protein Wnt-7a | chr3 | GO:0050679 | Not Cancer Driver | No | 93 | 0.266 | 18 | 9 | 0.5 | 4 |
| XBP1 | XBP1 | P17861 | X-box-binding protein 1 | chr22 | GO:0050679 | Not Cancer Driver | No | 19 | 0.073 | 169 | 9 | 0.053 | 0 |
| YAP1_ENST00000282441 | YAP1 | P46937 | Transcriptional coactivator YAP1 | chr11 | GO:0050679 | Not Cancer Driver | No | 51 | 0.101 | 489 | 49 | 0.1 | 0 |
| ZBED9 | ZBED9 | Q6R2W3 | SCAN domain-containing protein 3 | chr6 | GO:0050679 | Not Cancer Driver | No | 333 | 0.251 | 317 | 84 | 0.265 | 0 |
| ZNF304_ENST00000391705 | ZNF304 | Q9HCX3 | Zinc finger protein 304 | chr19 | GO:0050679 | Not Cancer Driver | No | 126 | 0.191 | 54 | 12 | 0.222 | 0 |
| ZNF580_ENST00000545125 | ZNF580 | Q9UK33 | Zinc finger protein 580 | chr19 | GO:0050679 | Not Cancer Driver | No | 8 | 0.047 | 153 | 8 | 0.052 | 0 |
| ZNF703 | ZNF703 | Q9H7S9 | Zinc finger protein 703 | chr8 | GO:0050679 | Not Cancer Driver | No | 26 | 0.044 | 415 | 14 | 0.034 | 0 |