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Total number of protein in "GO:0050673" GO term:  74

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACVR2A_ENST00000404590 ACVR2A P27037 Activin receptor type-2A chr2 GO:0050673 Census, Compendium Yes 98 0.191 56 6 0.107 0
ACVRL1 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0050673 Not Cancer Driver No 93 0.185 60 11 0.183 82
ANGPTL8_ENST00000252453 ANGPTL8 Q6UXH0 Angiopoietin-like protein 8 chr19 GO:0050673 Not Cancer Driver No 17 0.086 26 6 0.231 0
AREG AREG P15514 Amphiregulin chr4 GO:0050673 Not Cancer Driver No 28 0.111 149 20 0.134 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0050673 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0050673 Census Yes 30 0.156 39 2 0.051 0
BCL2L2 BCL2L2 Q92843 Bcl-2-like protein 2 chr14 GO:0050673 Not Cancer Driver No 22 0.114 34 6 0.176 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0050673 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMPER BMPER Q8N8U9 BMP-binding endothelial regulator protein chr7 GO:0050673 Not Cancer Driver No 196 0.286 0 0 0.0 1
BTBD10_ENST00000278174 BTBD10 Q9BSF8 BTB/POZ domain-containing protein 10 chr11 GO:0050673 Not Cancer Driver No 59 0.124 252 31 0.123 0
BTRC BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 GO:0050673 Not Cancer Driver No 80 0.132 45 4 0.089 0
C6orf89_ENST00000480824 C6orf89 Q6UWU4 Bombesin receptor-activated protein C6orf89 chr6 GO:0050673 Not Cancer Driver No 38 0.11 29 2 0.069 0
CCN3 CCN3 P48745 CCN family member 3 chr8 GO:0050673 Not Cancer Driver No 66 0.185 19 1 0.053 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 GO:0050673 Census, Compendium Yes 55 0.186 31 25 0.806 0
CDH13_ENST00000567109 CDH13 P55290 Cadherin-13 chr16 GO:0050673 Not Cancer Driver No 168 0.236 235 59 0.251 0
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0050673 Not Cancer Driver No 3 0.009 276 2 0.007 0
CLEC12B CLEC12B Q2HXU8 C-type lectin domain family 12 member B chr12 GO:0050673 Not Cancer Driver No 34 0.123 57 8 0.14 0
COL8A1_ENST00000273342 COL8A1 P27658 Collagen alpha-1(VIII) chain chr3 GO:0050673 Not Cancer Driver No 156 0.21 586 133 0.227 0
COL8A2_ENST00000303143 COL8A2 P25067 Collagen alpha-2(VIII) chain chr1 GO:0050673 Not Cancer Driver No 75 0.107 559 58 0.104 4
EHF_ENST00000533754 EHF Q9NZC4 ETS homologous factor chr11 GO:0050673 Not Cancer Driver No 43 0.143 50 7 0.14 0
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 GO:0050673 Compendium Yes 171 0.175 187 39 0.209 3
EREG EREG O14944 Proepiregulin chr4 GO:0050673 Not Cancer Driver No 26 0.154 10 3 0.3 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 GO:0050673 Census, Compendium Yes 121 0.203 195 27 0.138 2
FABP7_ENST00000368444 FABP7 O15540 Fatty acid-binding protein, brain chr6 GO:0050673 Not Cancer Driver No 20 0.152 0 0 0.0 0
FAP FAP Q12884 Prolyl endopeptidase FAP chr2 GO:0050673 Not Cancer Driver No 158 0.208 6 2 0.333 0
FERMT1 FERMT1 Q9BQL6 Fermitin family homolog 1 chr20 GO:0050673 Not Cancer Driver No 100 0.148 65 8 0.123 2
FGF10 FGF10 O15520 Fibroblast growth factor 10 chr5 GO:0050673 Not Cancer Driver No 56 0.269 34 11 0.324 2
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 GO:0050673 Census, Compendium Yes 238 0.29 228 44 0.193 72
FGL1_ENST00000381840 FGL1 Q08830 Fibrinogen-like protein 1 chr8 GO:0050673 Not Cancer Driver No 42 0.135 10 2 0.2 0
FSHB_ENST00000254122 FSHB P01225 Follitropin subunit beta chr11 GO:0050673 Not Cancer Driver No 31 0.24 0 0 0.0 1
FST FST P19883 Follistatin chr5 GO:0050673 Not Cancer Driver No 50 0.145 20 7 0.35 0
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0050673 Compendium Yes 233 0.32 43 16 0.372 0
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 GO:0050673 Not Cancer Driver No 14 0.104 52 7 0.135 0
IGFBP4 IGFBP4 P22692 Insulin-like growth factor-binding protein 4 chr17 GO:0050673 Not Cancer Driver No 24 0.093 106 17 0.16 0
IGFBP5 IGFBP5 P24593 Insulin-like growth factor-binding protein 5 chr2 GO:0050673 Not Cancer Driver No 27 0.099 112 17 0.152 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0050673 Not Cancer Driver No 35 0.165 58 7 0.121 0
IRF6 IRF6 O14896 Interferon regulatory factor 6 chr1 GO:0050673 Not Cancer Driver No 97 0.208 173 36 0.208 45
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0050673 Not Cancer Driver No 26 0.13 58 11 0.19 0
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0050673 Census, Compendium Yes 226 0.232 83 33 0.398 21
KLK8_ENST00000600767 KLK8 O60259 Kallikrein-8 chr19 GO:0050673 Not Cancer Driver No 65 0.25 76 15 0.197 0
KRT2 KRT2 P35908 Keratin, type II cytoskeletal 2 epidermal chr12 GO:0050673 Not Cancer Driver No 122 0.191 335 59 0.176 15
LGR4 LGR4 Q9BXB1 Leucine-rich repeat-containing G-protein coupled receptor 4 chr11 GO:0050673 Not Cancer Driver No 108 0.114 16 3 0.188 0
LGR5 LGR5 O75473 Leucine-rich repeat-containing G-protein coupled receptor 5 chr12 GO:0050673 Not Cancer Driver No 124 0.137 13 2 0.154 0
MAP2K1 MAP2K1 Q02750 Dual specificity mitogen-activated protein kinase kinase 1 chr15 GO:0050673 Census, Compendium Yes 94 0.239 96 24 0.25 6
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0050673 Census, Compendium Yes 62 0.172 2 0 0.0 7
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0050673 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0050673 Not Cancer Driver No 92 0.195 408 81 0.199 0
MTSS1_ENST00000518547 MTSS1 O43312 Protein MTSS 1 chr8 GO:0050673 Not Cancer Driver No 107 0.142 584 86 0.147 0
NCSTN NCSTN Q92542 Nicastrin chr1 GO:0050673 Not Cancer Driver No 94 0.133 72 11 0.153 1
NKX3-1 NKX3-1 Q99801 Homeobox protein Nkx-3.1 chr8 GO:0050673 Not Cancer Driver No 35 0.15 171 16 0.094 0
NKX6-1 NKX6-1 P78426 Homeobox protein Nkx-6.1 chr4 GO:0050673 Not Cancer Driver No 38 0.104 325 34 0.105 0
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0050673 Census, Compendium Yes 282 0.114 630 77 0.122 1
NRARP NRARP Q7Z6K4 Notch-regulated ankyrin repeat-containing protein chr9 GO:0050673 Not Cancer Driver No 9 0.079 11 1 0.091 0
OR51E2_ENST00000641638 OR51E2 Q9H255 Olfactory receptor 51E2 chr11 GO:0050673 Not Cancer Driver No 108 0.338 0 0 0.0 0
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 GO:0050673 Not Cancer Driver No 72 0.163 69 7 0.101 0
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:0050673 Not Cancer Driver No 182 0.247 537 141 0.263 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0050673 Not Cancer Driver No 61 0.131 134 21 0.157 96
PTCH1 PTCH1 Q13635 Protein patched homolog 1 chr9 GO:0050673 Census, Compendium Yes 243 0.168 382 67 0.175 18
PURA PURA Q00577 Transcriptional activator protein Pur-alpha chr5 GO:0050673 Not Cancer Driver No 22 0.068 188 10 0.053 6
RETNLB RETNLB Q9BQ08 Resistin-like beta chr3 GO:0050673 Not Cancer Driver No 32 0.288 0 0 0.0 0
RPS6KA1_ENST00000374168 RPS6KA1 Q15418 Ribosomal protein S6 kinase alpha-1 chr1 GO:0050673 Not Cancer Driver No 94 0.128 178 32 0.18 0
SDR16C5_ENST00000303749 SDR16C5 Q8N3Y7 Epidermal retinol dehydrogenase 2 chr8 GO:0050673 Not Cancer Driver No 81 0.262 4 0 0.0 0
SEMA5A SEMA5A Q13591 Semaphorin-5A chr5 GO:0050673 Not Cancer Driver No 266 0.248 23 4 0.174 0
SERPINB1 SERPINB1 P30740 Leukocyte elastase inhibitor chr6 GO:0050673 Not Cancer Driver No 39 0.103 14 0 0.0 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0050673 Not Cancer Driver No 56 0.121 139 14 0.101 81
SIDT2_ENST00000620360 SIDT2 Q8NBJ9 SID1 transmembrane family member 2 chr11 GO:0050673 Not Cancer Driver No 113 0.136 23 6 0.261 0
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0050673 Compendium Yes 86 0.169 495 82 0.166 18
STAT6_ENST00000543873 STAT6 P42226 Signal transducer and activator of transcription 6 chr12 GO:0050673 Census, Compendium Yes 106 0.125 325 44 0.135 0
TBX2 TBX2 Q13207 T-box transcription factor TBX2 chr17 GO:0050673 Not Cancer Driver No 74 0.104 401 36 0.09 1
TGFA_ENST00000295400 TGFA P01135 Protransforming growth factor alpha chr2 GO:0050673 Not Cancer Driver No 20 0.125 0 0 0.0 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0050673 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFSF11 TNFSF11 O14788 Tumor necrosis factor ligand superfamily member 11 chr13 GO:0050673 Not Cancer Driver No 52 0.164 56 1 0.018 1
WNT16 WNT16 Q9UBV4 Protein Wnt-16 chr7 GO:0050673 Not Cancer Driver No 59 0.162 28 9 0.321 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0050673 Not Cancer Driver No 66 0.174 0 0 0.0 2