Filter in search result
Please select a valid state.

Total number of protein in "GO:0048812" GO term:  124

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADARB1 ADARB1 P78563 Double-stranded RNA-specific editase 1 chr21 GO:0048812 Not Cancer Driver No 102 0.138 348 34 0.098 1
ADORA2A ADORA2A P29274 Adenosine receptor A2a chr22 GO:0048812 Not Cancer Driver No 61 0.148 93 11 0.118 0
ALS2 ALS2 Q96Q42 Alsin chr2 GO:0048812 Not Cancer Driver No 194 0.117 353 36 0.102 0
ANKRD27 ANKRD27 Q96NW4 Ankyrin repeat domain-containing protein 27 chr19 GO:0048812 Not Cancer Driver No 145 0.138 239 33 0.138 0
ARC ARC Q7LC44 Activity-regulated cytoskeleton-associated protein chr8 GO:0048812 Not Cancer Driver No 64 0.162 194 29 0.149 0
ARHGAP35_ENST00000614079 ARHGAP35 Q9NRY4 Rho GTPase-activating protein 35 chr19 GO:0048812 Census, Compendium Yes 255 0.17 409 58 0.142 0
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX GO:0048812 Not Cancer Driver No 228 0.152 171 46 0.269 52
B4GALT5 B4GALT5 O43286 Beta-1,4-galactosyltransferase 5 chr20 GO:0048812 Not Cancer Driver No 53 0.137 20 1 0.05 0
B4GALT6 B4GALT6 Q9UBX8 Beta-1,4-galactosyltransferase 6 chr18 GO:0048812 Not Cancer Driver No 47 0.123 13 2 0.154 0
BDNF_ENST00000439476 BDNF P23560 Brain-derived neurotrophic factor chr11 GO:0048812 Not Cancer Driver No 47 0.19 79 19 0.241 1
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0048812 Not Cancer Driver No 91 0.211 69 18 0.261 0
C12orf57 C12orf57 Q99622 Protein C10 chr12 GO:0048812 Not Cancer Driver No 13 0.103 29 1 0.034 1
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0048812 Not Cancer Driver No 39 0.204 23 2 0.087 1
CDH11 CDH11 P55287 Cadherin-11 chr16 GO:0048812 Census, Compendium Yes 264 0.332 399 127 0.318 0
CHRNA7_ENST00000306901 CHRNA7 P36544 Neuronal acetylcholine receptor subunit alpha-7 chr15 GO:0048812 Not Cancer Driver No 71 0.141 18 4 0.222 0
CHRNB2 CHRNB2 P17787 Neuronal acetylcholine receptor subunit beta-2 chr1 GO:0048812 Not Cancer Driver No 92 0.183 23 2 0.087 2
CNTNAP1 CNTNAP1 P78357 Contactin-associated protein 1 chr17 GO:0048812 Not Cancer Driver No 173 0.125 141 15 0.106 6
CNTNAP2 CNTNAP2 Q9UHC6 Contactin-associated protein-like 2 chr7 GO:0048812 Census Yes 570 0.428 161 82 0.509 0
CTNND2 CTNND2 Q9UQB3 Catenin delta-2 chr5 GO:0048812 Census Yes 386 0.315 837 254 0.303 0
CTTN_ENST00000301843 CTTN Q14247 Src substrate cortactin chr11 GO:0048812 Not Cancer Driver No 78 0.142 465 56 0.12 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0048812 Not Cancer Driver No 131 0.11 681 68 0.1 0
DBN1_ENST00000309007 DBN1 Q16643 Drebrin chr5 GO:0048812 Not Cancer Driver No 84 0.129 510 73 0.143 0
DBNL_ENST00000448521 DBNL Q9UJU6 Drebrin-like protein chr7 GO:0048812 Not Cancer Driver No 46 0.107 304 31 0.102 0
DCC DCC P43146 Netrin receptor DCC chr18 GO:0048812 Census, Compendium Yes 530 0.366 631 215 0.341 2
DCLK1 DCLK1 O15075 Serine/threonine-protein kinase DCLK1 chr13 GO:0048812 Not Cancer Driver No 209 0.282 252 77 0.306 0
DICER1 DICER1 Q9UPY3 Endoribonuclease Dicer chr14 GO:0048812 Census, Compendium Yes 264 0.137 362 45 0.124 4
DIP2A DIP2A Q14689 Disco-interacting protein 2 homolog A chr21 GO:0048812 Not Cancer Driver No 204 0.13 396 53 0.134 0
DLG4_ENST00000399506 DLG4 P78352 Disks large homolog 4 chr17 GO:0048812 Not Cancer Driver No 116 0.16 232 55 0.237 0
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 GO:0048812 Census Yes 138 0.159 270 43 0.159 22
DOCK10 DOCK10 Q96BY6 Dedicator of cytokinesis protein 10 chr2 GO:0048812 Not Cancer Driver No 368 0.168 409 58 0.142 0
DRAXIN DRAXIN Q8NBI3 Draxin chr1 GO:0048812 Not Cancer Driver No 61 0.175 249 48 0.193 0
DTNBP1 DTNBP1 Q96EV8 Dysbindin chr6 GO:0048812 Not Cancer Driver No 49 0.14 210 25 0.119 0
DVL1 DVL1 O14640 Segment polarity protein dishevelled homolog DVL-1 chr1 GO:0048812 Not Cancer Driver No 73 0.105 434 38 0.088 0
ECE1 ECE1 P42892 Endothelin-converting enzyme 1 chr1 GO:0048812 Not Cancer Driver No 118 0.153 99 26 0.263 1
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0048812 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDNRA EDNRA P25101 Endothelin-1 receptor chr4 GO:0048812 Not Cancer Driver No 62 0.145 21 6 0.286 2
EPB41L3 EPB41L3 Q9Y2J2 Band 4.1-like protein 3 chr18 GO:0048812 Not Cancer Driver No 298 0.274 695 207 0.298 0
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0048812 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHB1 EPHB1 P54762 Ephrin type-B receptor 1 chr3 GO:0048812 Not Cancer Driver No 316 0.321 67 17 0.254 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0048812 Not Cancer Driver No 186 0.176 119 17 0.143 7
EPHB3 EPHB3 P54753 Ephrin type-B receptor 3 chr3 GO:0048812 Not Cancer Driver No 155 0.155 137 16 0.117 0
EPHB6_ENST00000422643 EPHB6 O15197 Ephrin type-B receptor 6 chr7 GO:0048812 Not Cancer Driver No 227 0.222 246 45 0.183 0
FBXO45 FBXO45 P0C2W1 F-box/SPRY domain-containing protein 1 chr3 GO:0048812 Not Cancer Driver No 28 0.098 10 0 0.0 0
GAS7 GAS7 O60861 Growth arrest-specific protein 7 chr17 GO:0048812 Census Yes 78 0.164 318 57 0.179 0
GLI2_ENST00000361492 GLI2 P10070 Zinc finger protein GLI2 chr2 GO:0048812 Not Cancer Driver No 287 0.181 1403 244 0.174 2
GPM6A_ENST00000393658 GPM6A P51674 Neuronal membrane glycoprotein M6-a chr4 GO:0048812 Not Cancer Driver No 83 0.299 15 5 0.333 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX GO:0048812 Not Cancer Driver No 178 0.147 409 59 0.144 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 GO:0048812 Census, Compendium Yes 106 0.145 257 37 0.144 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0048812 Census, Compendium Yes 100 0.138 254 43 0.169 0
IGF2BP1 IGF2BP1 Q9NZI8 Insulin-like growth factor 2 mRNA-binding protein 1 chr17 GO:0048812 Not Cancer Driver No 141 0.244 298 80 0.268 0
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0048812 Not Cancer Driver No 85 0.244 180 41 0.228 0
ITGA1 ITGA1 P56199 Integrin alpha-1 chr5 GO:0048812 Not Cancer Driver No 156 0.132 107 13 0.121 0
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 GO:0048812 Not Cancer Driver No 254 0.246 97 27 0.278 0
KIF20B KIF20B Q96Q89 Kinesin-like protein KIF20B chr10 GO:0048812 Not Cancer Driver No 217 0.119 902 109 0.121 0
KIRREL3 KIRREL3 Q8IZU9 Kin of IRRE-like protein 3 chr11 GO:0048812 Not Cancer Driver No 111 0.143 223 32 0.143 0
KLK8_ENST00000600767 KLK8 O60259 Kallikrein-8 chr19 GO:0048812 Not Cancer Driver No 65 0.25 76 15 0.197 0
LRP2 LRP2 P98164 Low-density lipoprotein receptor-related protein 2 chr2 GO:0048812 Not Cancer Driver No 998 0.214 209 40 0.191 1
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0048812 Not Cancer Driver No 519 0.205 90 17 0.189 23
MAP1S MAP1S Q66K74 Microtubule-associated protein 1S chr19 GO:0048812 Not Cancer Driver No 118 0.111 527 48 0.091 0
MAP4K4_ENST00000347699 MAP4K4 O95819 Mitogen-activated protein kinase kinase kinase kinase 4 chr2 GO:0048812 Not Cancer Driver No 143 0.115 649 55 0.085 0
MINK1 MINK1 Q8N4C8 Misshapen-like kinase 1 chr17 GO:0048812 Not Cancer Driver No 113 0.085 740 56 0.076 0
MNX1 MNX1 P50219 Motor neuron and pancreas homeobox protein 1 chr7 GO:0048812 Census Yes 34 0.085 297 30 0.101 11
MYCBP2_ENST00000357337 MYCBP2 O75592 E3 ubiquitin-protein ligase MYCBP2 chr13 GO:0048812 Not Cancer Driver No 608 0.13 1398 189 0.135 0
MYO16_ENST00000357550 MYO16 Q9Y6X6 Unconventional myosin-XVI chr13 GO:0048812 Not Cancer Driver No 412 0.222 681 112 0.164 0
NBL1_ENST00000602662 NBL1 P41271 Neuroblastoma suppressor of tumorigenicity 1 chr1 GO:0048812 Not Cancer Driver No 18 0.099 64 4 0.062 0
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:0048812 Not Cancer Driver No 247 0.219 51 10 0.196 4
NCKAP1_ENST00000361354 NCKAP1 Q9Y2A7 Nck-associated protein 1 chr2 GO:0048812 Not Cancer Driver No 129 0.114 44 3 0.068 0
NDEL1 NDEL1 Q9GZM8 Nuclear distribution protein nudE-like 1 chr17 GO:0048812 Not Cancer Driver No 32 0.093 202 16 0.079 0
NEFH NEFH P12036 Neurofilament heavy polypeptide chr22 GO:0048812 Compendium Yes 114 0.111 871 106 0.122 0
NEFL NEFL P07196 Neurofilament light polypeptide chr8 GO:0048812 Not Cancer Driver No 92 0.169 285 39 0.137 12
NEK3 NEK3 P51956 Serine/threonine-protein kinase Nek3 chr13 GO:0048812 Not Cancer Driver No 44 0.087 203 17 0.084 0
NFIB_ENST00000380959 NFIB O00712 Nuclear factor 1 B-type chr9 GO:0048812 Census Yes 63 0.15 254 36 0.142 3
NGF NGF P01138 Beta-nerve growth factor chr1 GO:0048812 Not Cancer Driver No 66 0.274 93 25 0.269 1
NIN NIN Q8N4C6 Ninein chr14 GO:0048812 Census, Compendium Yes 239 0.114 1392 164 0.118 2
NLGN1_ENST00000361589 NLGN1 Q8N2Q7 Neuroligin-1 chr3 GO:0048812 Not Cancer Driver No 214 0.248 248 61 0.246 4
NPTX1 NPTX1 Q15818 Neuronal pentraxin-1 chr17 GO:0048812 Not Cancer Driver No 63 0.146 185 24 0.13 0
NR2E1_ENST00000368986 NR2E1 Q9Y466 Nuclear receptor subfamily 2 group E member 1 chr6 GO:0048812 Not Cancer Driver No 75 0.195 57 6 0.105 0
NR4A2_ENST00000409572 NR4A2 P43354 Nuclear receptor subfamily 4 group A member 2 chr2 GO:0048812 Not Cancer Driver No 110 0.184 261 38 0.146 0
NRK NRK Q7Z2Y5 Nik-related protein kinase chrX GO:0048812 Compendium Yes 315 0.199 812 159 0.196 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0048812 Compendium Yes 146 0.158 211 31 0.147 0
NTF3_ENST00000331010 NTF3 P20783 Neurotrophin-3 chr12 GO:0048812 Not Cancer Driver No 52 0.202 99 21 0.212 0
NTF4 NTF4 P34130 Neurotrophin-4 chr19 GO:0048812 Not Cancer Driver No 21 0.1 56 4 0.071 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0048812 Census, Compendium Yes 168 0.211 57 8 0.14 25
NYAP1 NYAP1 Q6ZVC0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1 chr7 GO:0048812 Not Cancer Driver No 128 0.152 792 126 0.159 0
NYAP2 NYAP2 Q9P242 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2 chr2 GO:0048812 Not Cancer Driver No 237 0.363 618 223 0.361 0
PACSIN1_ENST00000244458 PACSIN1 Q9BY11 Protein kinase C and casein kinase substrate in neurons protein 1 chr6 GO:0048812 Not Cancer Driver No 56 0.126 318 47 0.148 0
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:0048812 Not Cancer Driver No 42 0.102 82 11 0.134 7
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0048812 Not Cancer Driver No 57 0.105 299 30 0.1 2
PAK3_ENST00000262836 PAK3 O75914 Serine/threonine-protein kinase PAK 3 chrX GO:0048812 Not Cancer Driver No 127 0.227 286 64 0.224 2
PAK6_ENST00000260404 PAK6 Q9NQU5 Serine/threonine-protein kinase PAK 6 chr15 GO:0048812 Not Cancer Driver No 82 0.12 398 52 0.131 0
PHACTR1 PHACTR1 Q9C0D0 Phosphatase and actin regulator 1 chr6 GO:0048812 Not Cancer Driver No 81 0.14 447 59 0.132 3
PHOX2B PHOX2B Q99453 Paired mesoderm homeobox protein 2B chr4 GO:0048812 Census Yes 59 0.188 219 44 0.201 2
PLXNA4 PLXNA4 Q9HCM2 Plexin-A4 chr7 GO:0048812 Not Cancer Driver No 591 0.312 198 63 0.318 0
PLXNB1_ENST00000296440 PLXNB1 O43157 Plexin-B1 chr3 GO:0048812 Not Cancer Driver No 228 0.107 684 67 0.098 0
PRMT3 PRMT3 O60678 Protein arginine N-methyltransferase 3 chr11 GO:0048812 Not Cancer Driver No 68 0.128 52 9 0.173 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0048812 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTN PTN P21246 Pleiotrophin chr7 GO:0048812 Not Cancer Driver No 43 0.256 51 11 0.216 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0048812 Census, Compendium Yes 99 0.513 46 13 0.283 2
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0048812 Not Cancer Driver No 184 0.136 780 103 0.132 0
SEMA3A SEMA3A Q14563 Semaphorin-3A chr7 GO:0048812 Not Cancer Driver No 195 0.253 164 46 0.28 10
SGK1_ENST00000237305 SGK1 O00141 Serine/threonine-protein kinase Sgk1 chr6 GO:0048812 Census, Compendium Yes 58 0.135 86 16 0.186 0
SHANK1 SHANK1 Q9Y566 SH3 and multiple ankyrin repeat domains protein 1 chr19 GO:0048812 Not Cancer Driver No 288 0.133 1659 186 0.112 0
SHTN1 SHTN1 A0MZ66 Shootin-1 chr10 GO:0048812 Census Yes 68 0.108 470 52 0.111 0
SLC25A46 SLC25A46 Q96AG3 Mitochondrial outer membrane protein SLC25A46 chr5 GO:0048812 Not Cancer Driver No 37 0.089 96 2 0.021 4
SLC9A6_ENST00000370698 SLC9A6 Q92581 Sodium/hydrogen exchanger 6 chrX GO:0048812 Not Cancer Driver No 98 0.146 109 19 0.174 1
SPTBN4_ENST00000598249 SPTBN4 Q9H254 Spectrin beta chain, non-erythrocytic 4 chr19 GO:0048812 Not Cancer Driver No 312 0.122 866 103 0.119 0
SRGAP2 SRGAP2 O75044 SLIT-ROBO Rho GTPase-activating protein 2 chr1 GO:0048812 Not Cancer Driver No 122 0.114 541 71 0.131 0
SULT4A1 SULT4A1 Q9BR01 Sulfotransferase 4A1 chr22 GO:0048812 Not Cancer Driver No 46 0.162 17 2 0.118 0
SZT2_ENST00000634258 SZT2 Q5T011 KICSTOR complex protein SZT2 chr1 GO:0048812 Not Cancer Driver No 381 0.111 1292 161 0.125 1
TAOK1 TAOK1 Q7L7X3 Serine/threonine-protein kinase TAO1 chr17 GO:0048812 Not Cancer Driver No 116 0.116 601 59 0.098 0
TAOK2 TAOK2 Q9UL54 Serine/threonine-protein kinase TAO2 chr16 GO:0048812 Not Cancer Driver No 191 0.155 666 102 0.153 0
TAOK3 TAOK3 Q9H2K8 Serine/threonine-protein kinase TAO3 chr12 GO:0048812 Not Cancer Driver No 123 0.137 494 64 0.13 0
TCTN1_ENST00000551590 TCTN1 Q2MV58 Tectonic-1 chr12 GO:0048812 Not Cancer Driver No 63 0.107 47 6 0.128 0
TNIK TNIK Q9UKE5 TRAF2 and NCK-interacting protein kinase chr3 GO:0048812 Not Cancer Driver No 254 0.187 781 156 0.2 0
TPBG_ENST00000543496 TPBG Q13641 Trophoblast glycoprotein chr6 GO:0048812 Not Cancer Driver No 58 0.138 13 1 0.077 0
TRIO TRIO O75962 Triple functional domain protein chr5 GO:0048812 Not Cancer Driver No 400 0.129 1052 118 0.112 10
TSKU_ENST00000333090 TSKU Q8WUA8 Tsukushi chr11 GO:0048812 Not Cancer Driver No 53 0.15 44 6 0.136 0
UBB_ENST00000614404 UBB P0CG47 Polyubiquitin-B chr17 GO:0048812 Not Cancer Driver No 20 0.087 102 8 0.078 0
UGT8 UGT8 Q16880 2-hydroxyacylsphingosine 1-beta-galactosyltransferase chr4 GO:0048812 Not Cancer Driver No 107 0.198 18 2 0.111 0
WASL WASL O00401 Neural Wiskott-Aldrich syndrome protein chr7 GO:0048812 Not Cancer Driver No 72 0.143 394 57 0.145 0
WEE1 WEE1 P30291 Wee1-like protein kinase chr11 GO:0048812 Not Cancer Driver No 60 0.093 399 27 0.068 0
WNT7A WNT7A O00755 Protein Wnt-7a chr3 GO:0048812 Not Cancer Driver No 93 0.266 18 9 0.5 4
WNT7B WNT7B P56706 Protein Wnt-7b chr22 GO:0048812 Not Cancer Driver No 55 0.158 11 1 0.091 0
ZNF335 ZNF335 Q9H4Z2 Zinc finger protein 335 chr20 GO:0048812 Not Cancer Driver No 185 0.138 942 133 0.141 1