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Total number of protein in "GO:0048589" GO term:  240

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0048589 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACVR2B ACVR2B Q13705 Activin receptor type-2B chr3 GO:0048589 Not Cancer Driver No 83 0.162 70 14 0.2 2
ADAM15 ADAM15 Q13444 Disintegrin and metalloproteinase domain-containing protein 15 chr1 GO:0048589 Not Cancer Driver No 104 0.121 213 29 0.136 0
ADARB1 ADARB1 P78563 Double-stranded RNA-specific editase 1 chr21 GO:0048589 Not Cancer Driver No 102 0.138 348 34 0.098 1
ADM ADM P35318 Pro-adrenomedullin chr11 GO:0048589 Not Cancer Driver No 20 0.108 113 13 0.115 0
ADPRHL1 ADPRHL1 Q8NDY3 Inactive ADP-ribosyltransferase ARH2 chr13 GO:0048589 Not Cancer Driver No 52 0.147 32 7 0.219 0
ADRA1A_ENST00000380573 ADRA1A P35348 Alpha-1A adrenergic receptor chr8 GO:0048589 Not Cancer Driver No 130 0.279 40 8 0.2 0
AGT AGT P01019 Angiotensinogen chr1 GO:0048589 Not Cancer Driver No 85 0.179 33 10 0.303 1
AKAP13_ENST00000394518 AKAP13 Q12802 A-kinase anchor protein 13 chr15 GO:0048589 Not Cancer Driver No 359 0.128 2091 258 0.123 0
ALCAM ALCAM Q13740 CD166 antigen chr3 GO:0048589 Not Cancer Driver No 89 0.153 96 19 0.198 0
ALKBH1 ALKBH1 Q13686 Nucleic acid dioxygenase ALKBH1 chr14 GO:0048589 Not Cancer Driver No 55 0.141 77 11 0.143 0
APBA1 APBA1 Q02410 Amyloid-beta A4 precursor protein-binding family A member 1 chr9 GO:0048589 Not Cancer Driver No 149 0.178 556 103 0.185 0
APOA5 APOA5 Q6Q788 Apolipoprotein A-V chr11 GO:0048589 Not Cancer Driver No 51 0.139 178 26 0.146 0
APOD APOD P05090 Apolipoprotein D chr3 GO:0048589 Not Cancer Driver No 34 0.18 13 2 0.154 0
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0048589 Not Cancer Driver No 128 0.166 418 71 0.17 17
AR AR P10275 Androgen receptor chrX GO:0048589 Census, Compendium Yes 196 0.213 443 88 0.199 169
ARID5B ARID5B Q14865 AT-rich interactive domain-containing protein 5B chr10 GO:0048589 Not Cancer Driver No 162 0.136 769 95 0.124 0
ASPM ASPM Q8IZT6 Abnormal spindle-like microcephaly-associated protein chr1 GO:0048589 Not Cancer Driver No 554 0.159 424 67 0.158 0
ATF5_ENST00000595125 ATF5 Q9Y2D1 Cyclic AMP-dependent transcription factor ATF-5 chr19 GO:0048589 Not Cancer Driver No 47 0.167 239 40 0.167 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0048589 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATRX ATRX P46100 Transcriptional regulator ATRX chrX GO:0048589 Census, Compendium Yes 487 0.195 1672 301 0.18 33
AUTS2 AUTS2 Q8WXX7 Autism susceptibility gene 2 protein chr7 GO:0048589 Not Cancer Driver No 219 0.174 1218 213 0.175 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0048589 Census, Compendium Yes 24 0.1 72 5 0.069 0
BDNF_ENST00000439476 BDNF P23560 Brain-derived neurotrophic factor chr11 GO:0048589 Not Cancer Driver No 47 0.19 79 19 0.241 1
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0048589 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0048589 Census, Compendium Yes 66 0.124 21 0 0.0 8
BNC2 BNC2 Q6ZN30 Zinc finger protein basonuclin-2 chr9 GO:0048589 Not Cancer Driver No 242 0.22 682 150 0.22 1
CCL11 CCL11 P51671 Eotaxin chr17 GO:0048589 Not Cancer Driver No 18 0.186 14 3 0.214 0
CCM2_ENST00000258781 CCM2 Q9BSQ5 Cerebral cavernous malformations 2 protein chr7 GO:0048589 Not Cancer Driver No 58 0.131 132 8 0.061 3
CCN3 CCN3 P48745 CCN family member 3 chr8 GO:0048589 Not Cancer Driver No 66 0.185 19 1 0.053 0
CDKL3 CDKL3 Q8IVW4 Cyclin-dependent kinase-like 3 chr5 GO:0048589 Not Cancer Driver No 68 0.115 278 40 0.144 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 GO:0048589 Census, Compendium Yes 48 0.293 121 30 0.248 0
CDKN1C CDKN1C P49918 Cyclin-dependent kinase inhibitor 1C chr11 GO:0048589 Not Cancer Driver No 2 0.006 256 1 0.004 7
CELA1 CELA1 Q9UNI1 Chymotrypsin-like elastase family member 1 chr12 GO:0048589 Not Cancer Driver No 48 0.186 20 0 0.0 0
CFLAR CFLAR O15519 CASP8 and FADD-like apoptosis regulator chr2 GO:0048589 Not Cancer Driver No 40 0.083 44 2 0.045 0
CGA_ENST00000627148 CGA P01215 Glycoprotein hormones alpha chain chr6 GO:0048589 Not Cancer Driver No 28 0.241 0 0 0.0 0
CHRNA1_ENST00000348749 CHRNA1 P02708 Acetylcholine receptor subunit alpha chr2 GO:0048589 Not Cancer Driver No 86 0.188 9 1 0.111 12
CHRND CHRND Q07001 Acetylcholine receptor subunit delta chr2 GO:0048589 Not Cancer Driver No 110 0.213 71 19 0.268 7
CHST11 CHST11 Q9NPF2 Carbohydrate sulfotransferase 11 chr12 GO:0048589 Census Yes 69 0.196 45 11 0.244 0
CLIC4 CLIC4 Q9Y696 Chloride intracellular channel protein 4 chr1 GO:0048589 Not Cancer Driver No 24 0.095 49 4 0.082 0
COBL_ENST00000265136 COBL O75128 Protein cordon-bleu chr7 GO:0048589 Not Cancer Driver No 233 0.185 1149 216 0.188 0
COL3A1 COL3A1 P02461 Collagen alpha-1(III) chain chr2 GO:0048589 Census Yes 402 0.274 1182 337 0.285 103
COMP COMP P49747 Cartilage oligomeric matrix protein chr19 GO:0048589 Not Cancer Driver No 97 0.128 306 52 0.17 61
CPQ CPQ Q9Y646 Carboxypeptidase Q chr8 GO:0048589 Not Cancer Driver No 110 0.233 3 0 0.0 0
CSF1_ENST00000369802 CSF1 P09603 Macrophage colony-stimulating factor 1 chr1 GO:0048589 Not Cancer Driver No 69 0.125 339 46 0.136 0
CTC1 CTC1 Q2NKJ3 CST complex subunit CTC1 chr17 GO:0048589 Not Cancer Driver No 142 0.117 103 8 0.078 9
CTR9 CTR9 Q6PD62 RNA polymerase-associated protein CTR9 homolog chr11 GO:0048589 Not Cancer Driver No 164 0.14 385 48 0.125 0
CYFIP1_ENST00000610365 CYFIP1 Q7L576 Cytoplasmic FMR1-interacting protein 1 chr15 GO:0048589 Not Cancer Driver No 46 0.037 96 0 0.0 0
CYFIP2 CYFIP2 Q96F07 Cytoplasmic FMR1-interacting protein 2 chr5 GO:0048589 Not Cancer Driver No 211 0.165 86 11 0.128 3
CYP19A1_ENST00000396404 CYP19A1 P11511 Aromatase chr15 GO:0048589 Not Cancer Driver No 91 0.181 2 1 0.5 5
DAG1_ENST00000515359 DAG1 Q14118 Dystroglycan 1 chr3 GO:0048589 Not Cancer Driver No 102 0.114 485 61 0.126 4
DDR2 DDR2 Q16832 Discoidin domain-containing receptor 2 chr1 GO:0048589 Census Yes 192 0.225 118 34 0.288 7
DLL1 DLL1 O00548 Delta-like protein 1 chr6 GO:0048589 Not Cancer Driver No 115 0.159 145 24 0.166 1
DMBX1_ENST00000371956 DMBX1 Q8NFW5 Diencephalon/mesencephalon homeobox protein 1 chr1 GO:0048589 Not Cancer Driver No 93 0.243 272 69 0.254 0
DVL1 DVL1 O14640 Segment polarity protein dishevelled homolog DVL-1 chr1 GO:0048589 Not Cancer Driver No 73 0.105 434 38 0.088 0
ECM1_ENST00000369047 ECM1 Q16610 Extracellular matrix protein 1 chr1 GO:0048589 Not Cancer Driver No 91 0.169 219 28 0.128 1
EDN2 EDN2 P20800 Endothelin-2 chr1 GO:0048589 Not Cancer Driver No 21 0.118 87 13 0.149 0
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0048589 Not Cancer Driver No 34 0.149 25 6 0.24 0
EHMT2_ENST00000375537 EHMT2 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 chr6 GO:0048589 Not Cancer Driver No 142 0.117 585 71 0.121 0
EIF4H EIF4H Q15056 Eukaryotic translation initiation factor 4H chr7 GO:0048589 Not Cancer Driver No 30 0.121 175 17 0.097 0
EN1 EN1 Q05925 Homeobox protein engrailed-1 chr2 GO:0048589 Not Cancer Driver No 42 0.107 357 30 0.084 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0048589 Census, Compendium Yes 334 0.138 1790 196 0.109 1
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 GO:0048589 Census, Compendium Yes 428 0.327 323 116 0.359 2
ERCC1_ENST00000589165 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0048589 Not Cancer Driver No 42 0.141 105 14 0.133 1
ERCC2 ERCC2 P18074 General transcription and DNA repair factor IIH helicase subunit XPD chr19 GO:0048589 Census, Compendium Yes 150 0.197 5 0 0.0 35
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0048589 Not Cancer Driver No 211 0.141 829 117 0.141 9
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 GO:0048589 Census, Compendium Yes 121 0.203 195 27 0.138 2
ETNK2_ENST00000367202 ETNK2 Q9NVF9 Ethanolamine kinase 2 chr1 GO:0048589 Not Cancer Driver No 46 0.119 38 34 0.895 0
EVC EVC P57679 Ellis-van Creveld syndrome protein chr4 GO:0048589 Not Cancer Driver No 143 0.144 373 60 0.161 4
EXT1 EXT1 Q16394 Exostosin-1 chr8 GO:0048589 Census Yes 107 0.143 58 7 0.121 12
EYS EYS Q5T1H1 Protein eyes shut homolog chr6 GO:0048589 Not Cancer Driver No 447 0.141 109 9 0.083 16
FGF10 FGF10 O15520 Fibroblast growth factor 10 chr5 GO:0048589 Not Cancer Driver No 56 0.269 34 11 0.324 2
FGF1_ENST00000612258 FGF1 P05230 Fibroblast growth factor 1 chr5 GO:0048589 Not Cancer Driver No 30 0.194 29 2 0.069 0
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 GO:0048589 Census, Compendium Yes 238 0.29 228 44 0.193 72
FGFR3_ENST00000440486 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 GO:0048589 Census, Compendium Yes 173 0.215 241 26 0.108 37
FKBP8_ENST00000222308 FKBP8 Q14318 Peptidyl-prolyl cis-trans isomerase FKBP8 chr19 GO:0048589 Not Cancer Driver No 71 0.172 160 25 0.156 0
FLVCR1 FLVCR1 Q9Y5Y0 Feline leukemia virus subgroup C receptor-related protein 1 chr1 GO:0048589 Not Cancer Driver No 58 0.105 117 14 0.12 4
FMN1 FMN1 Q68DA7 Formin-1 chr15 GO:0048589 Not Cancer Driver No 117 0.082 983 67 0.068 0
FOXL2 FOXL2 P58012 Forkhead box protein L2 chr3 GO:0048589 Census, Compendium Yes 39 0.104 257 20 0.078 26
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0048589 Census, Compendium Yes 70 0.104 595 68 0.114 0
FZD9 FZD9 O00144 Frizzled-9 chr7 GO:0048589 Not Cancer Driver No 55 0.093 61 0 0.0 0
G6PC G6PC1 P35575 Glucose-6-phosphatase catalytic subunit 1 chr17 GO:0048589 Not Cancer Driver No 67 0.188 0 0 0.0 54
GAP43_ENST00000305124 GAP43 P17677 Neuromodulin chr3 GO:0048589 Not Cancer Driver No 79 0.332 238 79 0.332 0
GAS1 GAS1 P54826 Growth arrest-specific protein 1 chr9 GO:0048589 Not Cancer Driver No 13 0.038 82 4 0.049 0
GAS2 GAS2 O43903 Growth arrest-specific protein 2 chr11 GO:0048589 Not Cancer Driver No 73 0.233 92 16 0.174 0
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0048589 Census, Compendium Yes 111 0.251 364 87 0.239 2
GATA4_ENST00000335135 GATA4 P43694 Transcription factor GATA-4 chr8 GO:0048589 Not Cancer Driver No 48 0.109 301 34 0.113 18
GIGYF2_ENST00000409547 GIGYF2 Q6Y7W6 GRB10-interacting GYF protein 2 chr2 GO:0048589 Not Cancer Driver No 176 0.135 1096 158 0.144 6
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 GO:0048589 Not Cancer Driver No 86 0.225 110 26 0.236 50
GLI2_ENST00000361492 GLI2 P10070 Zinc finger protein GLI2 chr2 GO:0048589 Not Cancer Driver No 287 0.181 1403 244 0.174 2
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0048589 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GPR149 GPR149 Q86SP6 Probable G-protein coupled receptor 149 chr3 GO:0048589 Not Cancer Driver No 180 0.246 286 74 0.259 0
GPX1_ENST00000620890 GPX1 P07203 Glutathione peroxidase 1 chr3 GO:0048589 Not Cancer Driver No 38 0.187 12 1 0.083 0
GRHL2 GRHL2 Q6ISB3 Grainyhead-like protein 2 homolog chr8 GO:0048589 Not Cancer Driver No 95 0.152 258 43 0.167 2
H3F3A_ENST00000366816 H3-3B P84243 Histone H3.3 chr1 GO:0048589 Not Cancer Driver No 32 0.235 51 22 0.431 3
H3F3B_ENST00000589599 H3-3B P84243 Histone H3.3 chr17 GO:0048589 Not Cancer Driver No 28 0.206 51 14 0.275 3
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX GO:0048589 Not Cancer Driver No 178 0.147 409 59 0.144 0
HDGFL2 HDGFL2 Q7Z4V5 Hepatoma-derived growth factor-related protein 2 chr19 GO:0048589 Not Cancer Driver No 59 0.088 622 57 0.092 0
HEG1 HEG1 Q9ULI3 Protein HEG homolog 1 chr3 GO:0048589 Not Cancer Driver No 173 0.125 974 135 0.139 0
HELT HELT A6NFD8 Hairy and enhancer of split-related protein HELT chr4 GO:0048589 Not Cancer Driver No 39 0.161 131 21 0.16 0
HESX1 HESX1 Q9UBX0 Homeobox expressed in ES cells 1 chr3 GO:0048589 Not Cancer Driver No 32 0.173 59 9 0.153 6
HOXA11 HOXA11 P31270 Homeobox protein Hox-A11 chr7 GO:0048589 Census, Compendium Yes 37 0.118 205 26 0.127 0
HOXA5 HOXA5 P20719 Homeobox protein Hox-A5 chr7 GO:0048589 Not Cancer Driver No 43 0.159 209 37 0.177 0
HOXD13 HOXD13 P35453 Homeobox protein Hox-D13 chr2 GO:0048589 Census, Compendium Yes 43 0.125 113 12 0.106 9
IER3IP1 IER3IP1 Q9Y5U9 Immediate early response 3-interacting protein 1 chr18 GO:0048589 Not Cancer Driver No 3 0.037 0 0 0.0 2
IGFBP1 IGFBP1 P08833 Insulin-like growth factor-binding protein 1 chr7 GO:0048589 Not Cancer Driver No 47 0.181 42 7 0.167 0
IHH IHH Q14623 Indian hedgehog protein chr2 GO:0048589 Not Cancer Driver No 58 0.141 111 15 0.135 6
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 GO:0048589 Not Cancer Driver No 88 0.105 251 17 0.068 0
KDF1 KDF1 Q8NAX2 Keratinocyte differentiation factor 1 chr1 GO:0048589 Not Cancer Driver No 61 0.153 277 50 0.181 0
KDM5B_ENST00000367265 KDM5B Q9UGL1 Lysine-specific demethylase 5B chr1 GO:0048589 Not Cancer Driver No 219 0.142 388 58 0.149 0
KIF26B KIF26B Q2KJY2 Kinesin-like protein KIF26B chr1 GO:0048589 Not Cancer Driver No 369 0.175 1412 198 0.14 0
KLF2 KLF2 Q9Y5W3 Krueppel-like factor 2 chr19 GO:0048589 Not Cancer Driver No 13 0.037 280 4 0.014 0
KLK6 KLK6 Q92876 Kallikrein-6 chr19 GO:0048589 Not Cancer Driver No 62 0.254 28 12 0.429 0
KMT2D KMT2D O14686 Histone-lysine N-methyltransferase 2D chr12 GO:0048589 Census, Compendium Yes 773 0.14 4386 552 0.126 13
LAMB2 LAMB2 P55268 Laminin subunit beta-2 chr3 GO:0048589 Not Cancer Driver No 234 0.13 463 67 0.145 9
LARGE1 LARGE1 O95461 Xylosyl- and glucuronyltransferase LARGE1 chr22 GO:0048589 Not Cancer Driver No 131 0.173 92 16 0.174 4
LEP LEP P41159 Leptin chr7 GO:0048589 Not Cancer Driver No 29 0.174 0 0 0.0 2
LEPR LEPR P48357 Leptin receptor chr1 GO:0048589 Not Cancer Driver No 243 0.209 57 11 0.193 0
LGR6 LGR6 Q9HBX8 Leucine-rich repeat-containing G-protein coupled receptor 6 chr1 GO:0048589 Not Cancer Driver No 163 0.169 101 16 0.158 0
LLPH_ENST00000446587 LLPH Q9BRT6 Protein LLP homolog chr12 GO:0048589 Not Cancer Driver No 15 0.116 113 14 0.124 0
LRP4 LRP4 O75096 Low-density lipoprotein receptor-related protein 4 chr11 GO:0048589 Not Cancer Driver No 233 0.122 265 28 0.106 11
LY6E_ENST00000522024 LY6E Q16553 Lymphocyte antigen 6E chr8 GO:0048589 Not Cancer Driver No 13 0.099 0 0 0.0 0
LZTS2 LZTS2 Q9BRK4 Leucine zipper putative tumor suppressor 2 chr10 GO:0048589 Not Cancer Driver No 78 0.117 508 66 0.13 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0048589 Not Cancer Driver No 15 0.105 20 2 0.1 0
MED12 MED12 Q93074 Mediator of RNA polymerase II transcription subunit 12 chrX GO:0048589 Census, Compendium Yes 409 0.188 974 175 0.18 5
MESP1 MESP1 Q9BRJ9 Mesoderm posterior protein 1 chr15 GO:0048589 Not Cancer Driver No 8 0.03 247 7 0.028 0
MEX3C MEX3C Q5U5Q3 RNA-binding E3 ubiquitin-protein ligase MEX3C chr18 GO:0048589 Not Cancer Driver No 54 0.082 475 32 0.067 0
MSX2 MSX2 P35548 Homeobox protein MSX-2 chr5 GO:0048589 Not Cancer Driver No 27 0.101 168 14 0.083 4
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0048589 Census, Compendium Yes 379 0.149 296 37 0.125 18
MTPN MTPN P58546 Myotrophin chr7 GO:0048589 Not Cancer Driver No 11 0.093 11 3 0.273 0
MUSTN1 MUSTN1 Q8IVN3 Musculoskeletal embryonic nuclear protein 1 chr3 GO:0048589 Not Cancer Driver No 11 0.134 82 11 0.134 0
NBN NBN O60934 Nibrin chr8 GO:0048589 Census Yes 90 0.119 417 54 0.129 1
NIN NIN Q8N4C6 Ninein chr14 GO:0048589 Census, Compendium Yes 239 0.114 1392 164 0.118 2
NINJ1 NINJ1 Q92982 Ninjurin-1 chr9 GO:0048589 Not Cancer Driver No 17 0.112 29 0 0.0 0
NIPBL NIPBL Q6KC79 Nipped-B-like protein chr5 GO:0048589 Compendium Yes 353 0.126 1528 184 0.12 37
NLGN4X_ENST00000381093 NLGN4X Q8N0W4 Neuroligin-4, X-linked chrX GO:0048589 Not Cancer Driver No 279 0.342 211 81 0.384 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0048589 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0048589 Census, Compendium Yes 282 0.114 630 77 0.122 1
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0048589 Compendium Yes 146 0.158 211 31 0.147 0
NRP2 NRP2 O60462 Neuropilin-2 chr2 GO:0048589 Not Cancer Driver No 161 0.173 207 45 0.217 0
OSTN OSTN P61366 Osteocrin chr3 GO:0048589 Not Cancer Driver No 30 0.226 54 13 0.241 0
PALB2 PALB2 Q86YC2 Partner and localizer of BRCA2 chr16 GO:0048589 Census Yes 124 0.105 769 77 0.1 1
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0048589 Census, Compendium Yes 164 0.148 231 44 0.19 7
PDLIM5_ENST00000317968 PDLIM5 Q96HC4 PDZ and LIM domain protein 5 chr4 GO:0048589 Not Cancer Driver No 89 0.149 372 57 0.153 0
PKDCC PKDCC Q504Y2 Extracellular tyrosine-protein kinase PKDCC chr2 GO:0048589 Not Cancer Driver No 36 0.073 124 0 0.0 0
PLAG1_ENST00000429357 PLAG1 Q6DJT9 Zinc finger protein PLAG1 chr8 GO:0048589 Census, Compendium Yes 108 0.216 209 48 0.23 0
PLEC PLEC Q15149 Plectin chr8 GO:0048589 Not Cancer Driver No 677 0.145 2130 272 0.128 2
PLEKHA1 PLEKHA1 Q9HB21 Pleckstrin homology domain-containing family A member 1 chr10 GO:0048589 Not Cancer Driver No 61 0.151 191 32 0.168 0
PLG PLG P00747 Plasminogen chr6 GO:0048589 Not Cancer Driver No 242 0.299 230 64 0.278 9
PPP1R13L_ENST00000360957 PPP1R13L Q8WUF5 RelA-associated inhibitor chr19 GO:0048589 Not Cancer Driver No 117 0.141 657 90 0.137 0
PPP3CA PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 GO:0048589 Compendium Yes 85 0.163 140 27 0.193 7
PRLR PRLR P16471 Prolactin receptor chr5 GO:0048589 Not Cancer Driver No 154 0.248 282 70 0.248 2
PSAP PSAP P07602 Prosaposin chr10 GO:0048589 Not Cancer Driver No 59 0.113 28 2 0.071 8
PSAPL1 PSAPL1 Q6NUJ1 Proactivator polypeptide-like 1 chr4 GO:0048589 Not Cancer Driver No 62 0.119 7 1 0.143 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0048589 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTK7_ENST00000230419 PTK7 Q13308 Inactive tyrosine-protein kinase 7 chr6 GO:0048589 Not Cancer Driver No 153 0.143 359 58 0.162 0
PTN PTN P21246 Pleiotrophin chr7 GO:0048589 Not Cancer Driver No 43 0.256 51 11 0.216 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0048589 Census, Compendium Yes 129 0.218 260 38 0.146 60
PTPN12 PTPN12 Q05209 Tyrosine-protein phosphatase non-receptor type 12 chr7 GO:0048589 Not Cancer Driver No 102 0.131 516 60 0.116 0
PYGO2 PYGO2 Q9BRQ0 Pygopus homolog 2 chr1 GO:0048589 Not Cancer Driver No 51 0.126 340 43 0.126 0
RAD51B_ENST00000487270 RAD51B O15315 DNA repair protein RAD51 homolog 2 chr14 GO:0048589 Census Yes 45 0.117 13 0 0.0 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0048589 Census, Compendium Yes 70 0.152 167 14 0.084 0
RARG RARG P13631 Retinoic acid receptor gamma chr12 GO:0048589 Not Cancer Driver No 82 0.181 164 24 0.146 0
RBBP6 RBBP6 Q7Z6E9 E3 ubiquitin-protein ligase RBBP6 chr16 GO:0048589 Not Cancer Driver No 229 0.128 1626 212 0.13 0
RC3H2_ENST00000357244 RC3H2 Q9HBD1 Roquin-2 chr9 GO:0048589 Not Cancer Driver No 128 0.107 703 81 0.115 0
RDH10 RDH10 Q8IZV5 Retinol dehydrogenase 10 chr8 GO:0048589 Not Cancer Driver No 33 0.097 8 0 0.0 0
RMI1 RMI1 Q9H9A7 RecQ-mediated genome instability protein 1 chr9 GO:0048589 Not Cancer Driver No 67 0.107 243 26 0.107 0
RSPO2 RSPO2 Q6UXX9 R-spondin-2 chr8 GO:0048589 Census Yes 96 0.395 41 10 0.244 1
RTF1 RTF1 Q92541 RNA polymerase-associated protein RTF1 homolog chr15 GO:0048589 Not Cancer Driver No 83 0.117 568 67 0.118 0
RUNX1_ENST00000344691 RUNX1 Q01196 Runt-related transcription factor 1 chr21 GO:0048589 Census, Compendium Yes 81 0.179 360 58 0.161 2
S1PR1 S1PR1 P21453 Sphingosine 1-phosphate receptor 1 chr1 GO:0048589 Not Cancer Driver No 86 0.225 29 6 0.207 0
SALL1 SALL1 Q9NSC2 Sal-like protein 1 chr16 GO:0048589 Not Cancer Driver No 454 0.343 949 334 0.352 0
SCNN1B SCNN1B P51168 Amiloride-sensitive sodium channel subunit beta chr16 GO:0048589 Not Cancer Driver No 90 0.141 62 4 0.065 13
SELENOM_ENST00000611680 SELENOM Q8WWX9 Selenoprotein M chr22 GO:0048589 Not Cancer Driver No 10 0.069 21 2 0.095 0
SEMA3A SEMA3A Q14563 Semaphorin-3A chr7 GO:0048589 Not Cancer Driver No 195 0.253 164 46 0.28 10
SEMA3F SEMA3F Q13275 Semaphorin-3F chr3 GO:0048589 Not Cancer Driver No 114 0.145 194 27 0.139 0
SGCA SGCA Q16586 Alpha-sarcoglycan chr17 GO:0048589 Not Cancer Driver No 58 0.15 82 9 0.11 29
SH3GL2 SH3GL2 Q99962 Endophilin-A1 chr9 GO:0048589 Not Cancer Driver No 76 0.216 214 50 0.234 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0048589 Not Cancer Driver No 56 0.121 139 14 0.101 81
SLC12A5 SLC12A5 Q9H2X9 Solute carrier family 12 member 5 chr20 GO:0048589 Not Cancer Driver No 263 0.231 290 59 0.203 5
SLC1A2 SLC1A2 P43004 Excitatory amino acid transporter 2 chr11 GO:0048589 Not Cancer Driver No 77 0.134 81 7 0.086 3
SLC25A25_ENST00000373064 SLC25A25 Q6KCM7 Calcium-binding mitochondrial carrier protein SCaMC-2 chr9 GO:0048589 Not Cancer Driver No 45 0.096 5 1 0.2 0
SLC4A10 SLC4A10 Q6U841 Sodium-driven chloride bicarbonate exchanger chr2 GO:0048589 Not Cancer Driver No 221 0.198 340 68 0.2 0
SLC9A6_ENST00000370698 SLC9A6 Q92581 Sodium/hydrogen exchanger 6 chrX GO:0048589 Not Cancer Driver No 98 0.146 109 19 0.174 1
SLIT1 SLIT1 O75093 Slit homolog 1 protein chr10 GO:0048589 Not Cancer Driver No 221 0.144 36 1 0.028 0
SLIT2 SLIT2 O94813 Slit homolog 2 protein chr4 GO:0048589 Not Cancer Driver No 428 0.28 31 13 0.419 0
SLIT3_ENST00000519560 SLIT3 O75094 Slit homolog 3 protein chr5 GO:0048589 Not Cancer Driver No 351 0.23 40 9 0.225 0
SLITRK1 SLITRK1 Q96PX8 SLIT and NTRK-like protein 1 chr13 GO:0048589 Not Cancer Driver No 299 0.43 126 64 0.508 0
SLITRK6_ENST00000643778 SLITRK6 Q9H5Y7 SLIT and NTRK-like protein 6 chr13 GO:0048589 Not Cancer Driver No 244 0.29 225 53 0.236 0
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 GO:0048589 Census, Compendium Yes 79 0.169 137 12 0.088 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0048589 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0048589 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMO SMO Q99835 Smoothened homolog chr7 GO:0048589 Census, Compendium Yes 112 0.142 241 27 0.112 1
SMPD3 SMPD3 Q9NY59 Sphingomyelin phosphodiesterase 3 chr16 GO:0048589 Not Cancer Driver No 92 0.14 224 29 0.129 0
SORBS2_ENST00000284776 SORBS2 O94875 Sorbin and SH3 domain-containing protein 2 chr4 GO:0048589 Not Cancer Driver No 172 0.156 854 137 0.16 0
SOS1_ENST00000402219 SOS1 Q07889 Son of sevenless homolog 1 chr2 GO:0048589 Compendium Yes 197 0.148 458 62 0.135 38
SOX10_ENST00000360880 SOX10 P56693 Transcription factor SOX-10 chr22 GO:0048589 Not Cancer Driver No 66 0.142 421 62 0.147 14
SOX15_ENST00000538513 SOX15 O60248 Protein SOX-15 chr17 GO:0048589 Not Cancer Driver No 18 0.077 227 18 0.079 0
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 GO:0048589 Census Yes 39 0.123 312 39 0.125 0
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0048589 Compendium Yes 86 0.169 495 82 0.166 18
SP2 SP2 Q02086 Transcription factor Sp2 chr17 GO:0048589 Not Cancer Driver No 59 0.096 503 55 0.109 0
SPRY1 SPRY1 O43609 Protein sprouty homolog 1 chr4 GO:0048589 Not Cancer Driver No 46 0.144 168 26 0.155 0
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 GO:0048589 Not Cancer Driver No 46 0.146 169 29 0.172 1
SPTBN2 SPTBN2 O15020 Spectrin beta chain, non-erythrocytic 2 chr11 GO:0048589 Not Cancer Driver No 317 0.133 877 126 0.144 2
SRF SRF P11831 Serum response factor chr6 GO:0048589 Not Cancer Driver No 44 0.087 443 42 0.095 0
STIL_ENST00000360380 STIL Q15468 SCL-interrupting locus protein chr1 GO:0048589 Census, Compendium Yes 147 0.114 735 85 0.116 1
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:0048589 Census, Compendium Yes 75 0.173 135 14 0.104 9
STK40_ENST00000373132 STK40 Q8N2I9 Serine/threonine-protein kinase 40 chr1 GO:0048589 Not Cancer Driver No 50 0.115 103 9 0.087 0
STRA6_ENST00000323940 STRA6 Q9BX79 Receptor for retinol uptake STRA6 chr15 GO:0048589 Not Cancer Driver No 77 0.115 84 14 0.167 6
TAF10 TAF10 Q12962 Transcription initiation factor TFIID subunit 10 chr11 GO:0048589 Not Cancer Driver No 17 0.078 131 4 0.031 0
TAL2 TAL2 Q16559 T-cell acute lymphocytic leukemia protein 2 chr9 GO:0048589 Census Yes 18 0.167 81 14 0.173 0
TARBP2 TARBP2 Q15633 RISC-loading complex subunit TARBP2 chr12 GO:0048589 Not Cancer Driver No 45 0.123 203 22 0.108 0
TBL1XR1 TBL1XR1 Q9BZK7 F-box-like/WD repeat-containing protein TBL1XR1 chr3 GO:0048589 Census, Compendium Yes 82 0.16 136 19 0.14 4
TEC TEC P42680 Tyrosine-protein kinase Tec chr4 GO:0048589 Census, Compendium Yes 91 0.144 57 15 0.263 0
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0048589 Census, Compendium Yes 106 0.187 60 16 0.267 25
TM4SF4 TM4SF4 P48230 Transmembrane 4 L6 family member 4 chr3 GO:0048589 Not Cancer Driver No 36 0.178 0 0 0.0 0
TMED2 TMED2 Q15363 Transmembrane emp24 domain-containing protein 2 chr12 GO:0048589 Not Cancer Driver No 24 0.119 25 4 0.16 0
TMEM108 TMEM108 Q6UXF1 Transmembrane protein 108 chr3 GO:0048589 Not Cancer Driver No 101 0.176 458 89 0.194 0
TNKS2 TNKS2 Q9H2K2 Poly [ADP-ribose] polymerase tankyrase-2 chr10 GO:0048589 Not Cancer Driver No 117 0.1 255 24 0.094 0
TNS2_ENST00000314250 TNS2 Q63HR2 Tensin-2 chr12 GO:0048589 Not Cancer Driver No 132 0.094 799 63 0.079 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0048589 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TSKU_ENST00000333090 TSKU Q8WUA8 Tsukushi chr11 GO:0048589 Not Cancer Driver No 53 0.15 44 6 0.136 0
TTC8_ENST00000338104 TTC8 Q8TAM2 Tetratricopeptide repeat protein 8 chr14 GO:0048589 Not Cancer Driver No 74 0.137 98 12 0.122 0
TXK TXK P42681 Tyrosine-protein kinase TXK chr4 GO:0048589 Not Cancer Driver No 87 0.165 61 9 0.148 0
TYMS TYMS P04818 Thymidylate synthase chr18 GO:0048589 Not Cancer Driver No 22 0.07 41 0 0.0 0
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 GO:0048589 Not Cancer Driver No 141 0.161 136 22 0.162 0
UBTFL1 UBTFL1 P0CB47 Upstream-binding factor 1-like protein 1 chr11 GO:0048589 Not Cancer Driver No 13 0.033 257 9 0.035 0
WASF1_ENST00000392586 WASF1 Q92558 Wiskott-Aldrich syndrome protein family member 1 chr6 GO:0048589 Not Cancer Driver No 63 0.113 445 49 0.11 0
WDR11 WDR11 Q9BZH6 WD repeat-containing protein 11 chr10 GO:0048589 Not Cancer Driver No 122 0.1 94 6 0.064 6
WDR48 WDR48 Q8TAF3 WD repeat-containing protein 48 chr3 GO:0048589 Not Cancer Driver No 61 0.09 125 19 0.152 0
WDTC1 WDTC1 Q8N5D0 WD and tetratricopeptide repeats protein 1 chr1 GO:0048589 Not Cancer Driver No 81 0.12 154 21 0.136 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0048589 Not Cancer Driver No 77 0.219 37 5 0.135 0
WWTR1_ENST00000360632 WWTR1 Q9GZV5 WW domain-containing transcription regulator protein 1 chr3 GO:0048589 Census Yes 41 0.102 387 41 0.106 0
XRCC2 XRCC2 O43543 DNA repair protein XRCC2 chr7 GO:0048589 Not Cancer Driver No 36 0.129 9 1 0.111 2
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 GO:0048589 Not Cancer Driver No 51 0.101 489 49 0.1 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0048589 Compendium Yes 57 0.169 212 30 0.142 0
ZFY_ENST00000155093 ZFY P08048 Zinc finger Y-chromosomal protein chrY GO:0048589 Not Cancer Driver No 29 0.036 357 8 0.022 0
ZMIZ1 ZMIZ1 Q9ULJ6 Zinc finger MIZ domain-containing protein 1 chr10 GO:0048589 Not Cancer Driver No 148 0.139 762 111 0.146 5
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 GO:0048589 Not Cancer Driver No 67 0.141 23 0 0.0 3
ZNF830 ZNF830 Q96NB3 Zinc finger protein 830 chr17 GO:0048589 Not Cancer Driver No 39 0.105 312 37 0.119 0