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Total number of protein in "GO:0048585" GO term:  1103

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
A2M A2M P01023 Alpha-2-macroglobulin chr12 GO:0048585 Not Cancer Driver No 260 0.176 144 22 0.153 0
ABAT_ENST00000268251 ABAT P80404 4-aminobutyrate aminotransferase, mitochondrial chr16 GO:0048585 Not Cancer Driver No 84 0.168 28 5 0.179 1
ABCA7 ABCA7 Q8IZY2 Phospholipid-transporting ATPase ABCA7 chr19 GO:0048585 Not Cancer Driver No 260 0.121 402 35 0.087 1
ABCC8_ENST00000389817 ABCC8 Q09428 ATP-binding cassette sub-family C member 8 chr11 GO:0048585 Not Cancer Driver No 255 0.161 138 23 0.167 97
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0048585 Census, Compendium Yes 139 0.123 604 73 0.121 2
ABL2 ABL2 P42684 Tyrosine-protein kinase ABL2 chr1 GO:0048585 Census, Compendium Yes 171 0.145 641 70 0.109 0
ACAA2 ACAA2 P42765 3-ketoacyl-CoA thiolase, mitochondrial chr18 GO:0048585 Not Cancer Driver No 42 0.106 51 2 0.039 0
ACE2 ACE2 Q9BYF1 Angiotensin-converting enzyme 2 chrX GO:0048585 Not Cancer Driver No 104 0.129 68 5 0.074 0
ACKR3 ACKR3 P25106 Atypical chemokine receptor 3 chr2 GO:0048585 Census, Compendium Yes 78 0.215 0 0 0.0 1
ACOD1 ACOD1 A6NK06 Cis-aconitate decarboxylase chr13 GO:0048585 Not Cancer Driver No 5 0.01 36 0 0.0 0
ACP4 ACP4 Q9BZG2 Testicular acid phosphatase chr19 GO:0048585 Not Cancer Driver No 66 0.155 28 7 0.25 3
ACTN3_ENST00000513398 ACTN3 Q08043 Alpha-actinin-3 chr11 GO:0048585 Not Cancer Driver No 123 0.137 135 13 0.096 0
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0048585 Census, Compendium Yes 78 0.153 21 8 0.381 8
ADA ADA P00813 Adenosine deaminase chr20 GO:0048585 Not Cancer Driver No 50 0.138 44 9 0.205 27
ADAMTS12 ADAMTS12 P58397 A disintegrin and metalloproteinase with thrombospondin motifs 12 chr5 GO:0048585 Not Cancer Driver No 504 0.316 374 128 0.342 0
ADAMTS18 ADAMTS18 Q8TE60 A disintegrin and metalloproteinase with thrombospondin motifs 18 chr16 GO:0048585 Not Cancer Driver No 382 0.313 142 63 0.444 2
ADAR ADAR P55265 Double-stranded RNA-specific adenosine deaminase chr1 GO:0048585 Not Cancer Driver No 149 0.122 675 83 0.123 12
ADGRA2 ADGRA2 Q96PE1 Adhesion G protein-coupled receptor A2 chr8 GO:0048585 Not Cancer Driver No 140 0.105 417 32 0.077 0
ADGRG3 ADGRG3 Q86Y34 Adhesion G protein-coupled receptor G3 chr16 GO:0048585 Not Cancer Driver No 87 0.158 42 5 0.119 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0048585 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADIPOR1 ADIPOR1 Q96A54 Adiponectin receptor protein 1 chr1 GO:0048585 Not Cancer Driver No 63 0.168 69 10 0.145 0
ADORA1 ADORA1 P30542 Adenosine receptor A1 chr1 GO:0048585 Not Cancer Driver No 64 0.196 12 4 0.333 0
ADORA2A ADORA2A P29274 Adenosine receptor A2a chr22 GO:0048585 Not Cancer Driver No 61 0.148 93 11 0.118 0
ADRA1A_ENST00000380573 ADRA1A P35348 Alpha-1A adrenergic receptor chr8 GO:0048585 Not Cancer Driver No 130 0.279 40 8 0.2 0
ADRA2A ADRA2A P08913 Alpha-2A adrenergic receptor chr10 GO:0048585 Not Cancer Driver No 67 0.144 161 10 0.062 0
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 GO:0048585 Not Cancer Driver No 52 0.126 35 4 0.114 0
ADRB3 ADRB3 P13945 Beta-3 adrenergic receptor chr8 GO:0048585 Not Cancer Driver No 40 0.098 44 6 0.136 0
AES_ENST00000327141 TLE5 Q08117 TLE family member 5 chr19 GO:0048585 Not Cancer Driver No 16 0.081 77 7 0.091 0
AGT AGT P01019 Angiotensinogen chr1 GO:0048585 Not Cancer Driver No 85 0.179 33 10 0.303 1
AGTR2 AGTR2 P50052 Type-2 angiotensin II receptor chrX GO:0048585 Not Cancer Driver No 98 0.27 0 0 0.0 0
AHR AHR P35869 Aryl hydrocarbon receptor chr7 GO:0048585 Not Cancer Driver No 129 0.152 351 75 0.214 0
AHSG AHSG P02765 Alpha-2-HS-glycoprotein chr3 GO:0048585 Not Cancer Driver No 74 0.202 131 41 0.313 0
AIDA AIDA Q96BJ3 Axin interactor, dorsalization-associated protein chr1 GO:0048585 Not Cancer Driver No 36 0.118 87 9 0.103 0
AIF1 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0048585 Not Cancer Driver No 14 0.095 61 6 0.098 0
AJAP1 AJAP1 Q9UKB5 Adherens junction-associated protein 1 chr1 GO:0048585 Not Cancer Driver No 103 0.251 271 64 0.236 0
AJUBA AJUBA Q96IF1 LIM domain-containing protein ajuba chr14 GO:0048585 Compendium Yes 45 0.084 307 13 0.042 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0048585 Census, Compendium Yes 108 0.225 158 24 0.152 4
AKT3_ENST00000366539 AKT3 Q9Y243 RAC-gamma serine/threonine-protein kinase chr1 GO:0048585 Census, Compendium Yes 92 0.192 131 24 0.183 3
ALOX12 ALOX12 P18054 Polyunsaturated fatty acid lipoxygenase ALOX12 chr17 GO:0048585 Not Cancer Driver No 73 0.11 73 12 0.164 0
ALOX15_ENST00000293761 ALOX15 P16050 Polyunsaturated fatty acid lipoxygenase ALOX15 chr17 GO:0048585 Not Cancer Driver No 84 0.127 46 7 0.152 0
ALOX5 ALOX5 P09917 Polyunsaturated fatty acid 5-lipoxygenase chr10 GO:0048585 Not Cancer Driver No 129 0.191 16 2 0.125 0
ALPK2 ALPK2 Q86TB3 Alpha-protein kinase 2 chr18 GO:0048585 Not Cancer Driver No 406 0.187 1553 306 0.197 0
AMBP AMBP P02760 Protein AMBP chr9 GO:0048585 Not Cancer Driver No 57 0.162 61 15 0.246 0
ANGPT2 ANGPT2 O15123 Angiopoietin-2 chr8 GO:0048585 Not Cancer Driver No 63 0.127 96 10 0.104 1
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0048585 Not Cancer Driver No 59 0.171 61 12 0.197 0
APCS APCS P02743 Serum amyloid P-component chr1 GO:0048585 Not Cancer Driver No 73 0.327 0 0 0.0 0
APLN APLN Q9ULZ1 Apelin chrX GO:0048585 Not Cancer Driver No 8 0.104 51 6 0.118 0
APLP1 APLP1 P51693 Amyloid beta precursor like protein 1 chr19 GO:0048585 Not Cancer Driver No 146 0.225 455 98 0.215 0
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 GO:0048585 Not Cancer Driver No 28 0.105 131 8 0.061 3
APOD APOD P05090 Apolipoprotein D chr3 GO:0048585 Not Cancer Driver No 34 0.18 13 2 0.154 0
APOE APOE P02649 Apolipoprotein E chr19 GO:0048585 Not Cancer Driver No 25 0.079 124 6 0.048 12
APPL1 APPL1 Q9UKG1 DCC-interacting protein 13-alpha chr3 GO:0048585 Not Cancer Driver No 67 0.094 292 31 0.106 1
APPL2_ENST00000258530 APPL2 Q8NEU8 DCC-interacting protein 13-beta chr12 GO:0048585 Not Cancer Driver No 70 0.105 149 14 0.094 0
AQP11 AQP11 Q8NBQ7 Aquaporin-11 chr11 GO:0048585 Not Cancer Driver No 23 0.085 0 0 0.0 0
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:0048585 Not Cancer Driver No 41 0.127 83 12 0.145 9
ARG2 ARG2 P78540 Arginase-2, mitochondrial chr14 GO:0048585 Not Cancer Driver No 25 0.071 58 3 0.052 0
ARHGAP24 ARHGAP24 Q8N264 Rho GTPase-activating protein 24 chr4 GO:0048585 Not Cancer Driver No 103 0.138 482 67 0.139 0
ARHGAP35_ENST00000614079 ARHGAP35 Q9NRY4 Rho GTPase-activating protein 35 chr19 GO:0048585 Census, Compendium Yes 255 0.17 409 58 0.142 0
ARHGAP42 ARHGAP42 A6NI28 Rho GTPase-activating protein 42 chr11 GO:0048585 Not Cancer Driver No 63 0.072 311 17 0.055 0
ARHGAP44 ARHGAP44 Q17R89 Rho GTPase-activating protein 44 chr17 GO:0048585 Not Cancer Driver No 126 0.154 424 67 0.158 0
ARHGEF2 ARHGEF2 Q92974 Rho guanine nucleotide exchange factor 2 chr1 GO:0048585 Not Cancer Driver No 146 0.148 450 70 0.156 0
ARMC10 ARMC10 Q8N2F6 Armadillo repeat-containing protein 10 chr7 GO:0048585 Not Cancer Driver No 39 0.114 58 4 0.069 0
ARNTL ARNTL O00327 Aryl hydrocarbon receptor nuclear translocator-like protein 1 chr11 GO:0048585 Not Cancer Driver No 71 0.113 332 40 0.12 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0048585 Not Cancer Driver No 46 0.112 122 22 0.18 0
ARRDC3 ARRDC3 Q96B67 Arrestin domain-containing protein 3 chr5 GO:0048585 Not Cancer Driver No 52 0.126 95 12 0.126 0
ASH1L_ENST00000368346 ASH1L Q9NR48 Histone-lysine N-methyltransferase ASH1L chr1 GO:0048585 Not Cancer Driver No 415 0.14 1858 256 0.138 1
ASXL1_ENST00000613218 ASXL1 Q8IXJ9 Polycomb group protein ASXL1 chr20 GO:0048585 Census, Compendium Yes 205 0.133 1300 174 0.134 0
ATAD5 ATAD5 Q96QE3 ATPase family AAA domain-containing protein 5 chr17 GO:0048585 Not Cancer Driver No 200 0.108 1075 112 0.104 0
ATF3_ENST00000366987 ATF3 P18847 Cyclic AMP-dependent transcription factor ATF-3 chr1 GO:0048585 Not Cancer Driver No 23 0.127 118 14 0.119 0
ATF6B ATF6B Q99941 Cyclic AMP-dependent transcription factor ATF-6 beta chr6 GO:0048585 Not Cancer Driver No 70 0.1 557 59 0.106 0
ATG12 ATG12 O94817 Ubiquitin-like protein ATG12 chr5 GO:0048585 Not Cancer Driver No 15 0.107 60 8 0.133 0
ATG5_ENST00000343245 ATG5 Q9H1Y0 Autophagy protein 5 chr6 GO:0048585 Not Cancer Driver No 40 0.145 25 6 0.24 1
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0048585 Census, Compendium Yes 469 0.153 225 39 0.173 41
AUNIP_ENST00000374298 AUNIP Q9H7T9 Aurora kinase A and ninein-interacting protein chr1 GO:0048585 Not Cancer Driver No 23 0.064 341 21 0.062 0
AVP AVP P01185 Vasopressin-neurophysin 2-copeptin chr20 GO:0048585 Not Cancer Driver No 14 0.085 26 0 0.0 39
AXIN2 AXIN2 Q9Y2T1 Axin-2 chr17 GO:0048585 Census, Compendium Yes 114 0.135 547 77 0.141 0
BACE1 BACE1 P56817 Beta-secretase 1 chr11 GO:0048585 Not Cancer Driver No 55 0.11 53 5 0.094 0
BAG5_ENST00000299204 BAG5 Q9UL15 BAG family molecular chaperone regulator 5 chr14 GO:0048585 Not Cancer Driver No 37 0.083 63 7 0.111 0
BANF1_ENST00000445560 BANF1 O75531 Barrier-to-autointegration factor chr11 GO:0048585 Not Cancer Driver No 10 0.112 11 2 0.182 1
BANK1 BANK1 Q8NDB2 B-cell scaffold protein with ankyrin repeats chr4 GO:0048585 Not Cancer Driver No 150 0.191 394 73 0.185 0
BBS2 BBS2 Q9BXC9 Bardet-Biedl syndrome 2 protein chr16 GO:0048585 Not Cancer Driver No 90 0.125 76 16 0.211 20
BBS4 BBS4 Q96RK4 Bardet-Biedl syndrome 4 protein chr15 GO:0048585 Not Cancer Driver No 58 0.112 110 16 0.145 9
BCL2L1 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 GO:0048585 Not Cancer Driver No 29 0.124 55 3 0.055 0
BCL2L2 BCL2L2 Q92843 Bcl-2-like protein 2 chr14 GO:0048585 Not Cancer Driver No 22 0.114 34 6 0.176 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0048585 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCL3 BCL3 P20749 B-cell lymphoma 3 protein chr19 GO:0048585 Census Yes 44 0.097 259 23 0.089 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0048585 Census, Compendium Yes 134 0.19 328 67 0.204 0
BCR BCR P11274 Breakpoint cluster region protein chr22 GO:0048585 Census, Compendium Yes 146 0.115 603 69 0.114 0
BDKRB2 BDKRB2 P30411 B2 bradykinin receptor chr14 GO:0048585 Not Cancer Driver No 81 0.207 0 0 0.0 0
BFAR BFAR Q9NZS9 Bifunctional apoptosis regulator chr16 GO:0048585 Not Cancer Driver No 56 0.124 30 1 0.033 0
BICD1 BICD1 Q96G01 Protein bicaudal D homolog 1 chr12 GO:0048585 Not Cancer Driver No 124 0.127 656 86 0.131 0
BID_ENST00000551952 BID P55957 BH3-interacting domain death agonist chr22 GO:0048585 Not Cancer Driver No 23 0.118 74 9 0.122 0
BIRC7 BIRC7 Q96CA5 Baculoviral IAP repeat-containing protein 7 chr20 GO:0048585 Not Cancer Driver No 52 0.174 136 22 0.162 0
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0048585 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP5 BMP5 P22003 Bone morphogenetic protein 5 chr6 GO:0048585 Census Yes 163 0.359 112 62 0.554 0
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0048585 Not Cancer Driver No 91 0.211 69 18 0.261 0
BMT2 BMT2 Q1RMZ1 S-adenosylmethionine sensor upstream of mTORC1 chr7 GO:0048585 Not Cancer Driver No 65 0.16 81 10 0.123 0
BOK BOK Q9UMX3 Bcl-2-related ovarian killer protein chr2 GO:0048585 Not Cancer Driver No 7 0.033 0 0 0.0 0
BPIFB1 BPIFB1 Q8TDL5 BPI fold-containing family B member 1 chr20 GO:0048585 Not Cancer Driver No 93 0.192 7 0 0.0 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 GO:0048585 Census, Compendium Yes 224 0.12 1458 174 0.119 35
BTN2A2 BTN2A2 Q8WVV5 Butyrophilin subfamily 2 member A2 chr6 GO:0048585 Not Cancer Driver No 92 0.176 24 2 0.083 0
BTRC BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 GO:0048585 Not Cancer Driver No 80 0.132 45 4 0.089 0
C12orf66_ENST00000398055 KICS2 Q96MD2 KICSTOR subunit 2 chr12 GO:0048585 Not Cancer Driver No 61 0.137 35 6 0.171 0
C16orf72 TAPR1 Q14CZ0 Telomere attrition and p53 response 1 protein chr16 GO:0048585 Not Cancer Driver No 33 0.12 201 21 0.104 0
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 GO:0048585 Not Cancer Driver No 14 0.05 103 6 0.058 2
C1QL4 C1QL4 Q86Z23 Complement C1q-like protein 4 chr12 GO:0048585 Not Cancer Driver No 19 0.08 101 5 0.05 0
C1QTNF1_ENST00000581774 C1QTNF1 Q9BXJ1 Complement C1q tumor necrosis factor-related protein 1 chr17 GO:0048585 Not Cancer Driver No 61 0.217 96 17 0.177 0
C1QTNF3_ENST00000231338 C1QTNF3 Q9BXJ4 Complement C1q tumor necrosis factor-related protein 3 chr5 GO:0048585 Not Cancer Driver No 42 0.171 73 14 0.192 0
C3orf33 C3orf33 Q6P1S2 Protein C3orf33 chr3 GO:0048585 Not Cancer Driver No 30 0.102 23 0 0.0 0
C4BPA C4BPA P04003 C4b-binding protein alpha chain chr1 GO:0048585 Not Cancer Driver No 109 0.183 40 10 0.25 0
C4BPB C4BPB P20851 C4b-binding protein beta chain chr1 GO:0048585 Not Cancer Driver No 40 0.159 0 0 0.0 0
C5 C5 P01031 Complement C5 chr9 GO:0048585 Not Cancer Driver No 192 0.115 84 9 0.107 0
C5AR2_ENST00000600626 C5AR2 Q9P296 C5a anaphylatoxin chemotactic receptor 2 chr19 GO:0048585 Not Cancer Driver No 60 0.178 11 3 0.273 0
C6orf106 ILRUN Q9H6K1 Protein ILRUN chr6 GO:0048585 Not Cancer Driver No 23 0.077 113 6 0.053 0
CAAP1 CAAP1 Q9H8G2 Caspase activity and apoptosis inhibitor 1 chr9 GO:0048585 Not Cancer Driver No 28 0.078 234 18 0.077 0
CACTIN CACTIN Q8WUQ7 Cactin chr19 GO:0048585 Not Cancer Driver No 94 0.124 503 54 0.107 0
CADM4 CADM4 Q8NFZ8 Cell adhesion molecule 4 chr19 GO:0048585 Not Cancer Driver No 48 0.124 94 9 0.096 0
CALR CALR P27797 Calreticulin chr19 GO:0048585 Census Yes 45 0.108 245 31 0.127 0
CARD16 CARD16 Q5EG05 Caspase recruitment domain-containing protein 16 chr11 GO:0048585 Not Cancer Driver No 36 0.183 23 7 0.304 0
CARD8_ENST00000519940 CARD8 Q9Y2G2 Caspase recruitment domain-containing protein 8 chr19 GO:0048585 Not Cancer Driver No 53 0.099 126 7 0.056 1
CARTPT CARTPT Q16568 Cocaine- and amphetamine-regulated transcript protein chr5 GO:0048585 Not Cancer Driver No 18 0.155 0 0 0.0 0
CASK_ENST00000378163 CASK O14936 Peripheral plasma membrane protein CASK chrX GO:0048585 Not Cancer Driver No 118 0.127 285 45 0.158 4
CASTOR1 CASTOR1 Q8WTX7 Cytosolic arginine sensor for mTORC1 subunit 1 chr22 GO:0048585 Not Cancer Driver No 27 0.082 39 5 0.128 0
CASTOR3 CASTOR3 Q8NAP1 Putative protein CASTOR 3 chr7 GO:0048585 Not Cancer Driver No 18 0.11 1 0 0.0 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0048585 Not Cancer Driver No 30 0.169 2 0 0.0 0
CAVIN3 CAVIN3 Q969G5 Caveolae-associated protein 3 chr11 GO:0048585 Not Cancer Driver No 22 0.084 234 19 0.081 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0048585 Census, Compendium Yes 115 0.127 512 56 0.109 4
CBLB CBLB Q13191 E3 ubiquitin-protein ligase CBL-B chr3 GO:0048585 Census Yes 160 0.163 562 104 0.185 0
CBLC_ENST00000647358 CBLC Q9ULV8 E3 ubiquitin-protein ligase CBL-C chr19 GO:0048585 Census Yes 60 0.127 128 21 0.164 0
CBLN1 CBLN1 P23435 Cerebellin-1 chr16 GO:0048585 Not Cancer Driver No 46 0.238 14 2 0.143 0
CCAR2 CCAR2 Q8N163 Cell cycle and apoptosis regulator protein 2 chr8 GO:0048585 Not Cancer Driver No 102 0.111 528 62 0.117 0
CCDC125_ENST00000396499 CCDC125 Q86Z20 Coiled-coil domain-containing protein 125 chr5 GO:0048585 Not Cancer Driver No 58 0.114 261 23 0.088 0
CCDC3 CCDC3 Q9BQI4 Coiled-coil domain-containing protein 3 chr10 GO:0048585 Not Cancer Driver No 40 0.148 68 18 0.265 0
CCL2 CCL2 P13500 C-C motif chemokine 2 chr17 GO:0048585 Not Cancer Driver No 20 0.202 15 5 0.333 0
CCN3 CCN3 P48745 CCN family member 3 chr8 GO:0048585 Not Cancer Driver No 66 0.185 19 1 0.053 0
CCR2_ENST00000400888 CCR2 P41597 C-C chemokine receptor type 2 chr3 GO:0048585 Not Cancer Driver No 81 0.217 23 1 0.043 0
CD109 CD109 Q6YHK3 CD109 antigen chr6 GO:0048585 Not Cancer Driver No 204 0.141 54 11 0.204 0
CD160_ENST00000369288 CD160 O95971 CD160 antigen chr1 GO:0048585 Not Cancer Driver No 20 0.11 2 0 0.0 0
CD200R1_ENST00000471858 CD200R1 Q8TD46 Cell surface glycoprotein CD200 receptor 1 chr3 GO:0048585 Not Cancer Driver No 87 0.268 56 12 0.214 0
CD200_ENST00000315711 CD200 P41217 OX-2 membrane glycoprotein chr3 GO:0048585 Not Cancer Driver No 37 0.133 14 0 0.0 0
CD22 CD22 P20273 B-cell receptor CD22 chr19 GO:0048585 Not Cancer Driver No 173 0.204 290 66 0.228 0
CD300A CD300A Q9UGN4 CMRF35-like molecule 8 chr17 GO:0048585 Not Cancer Driver No 53 0.177 70 10 0.143 0
CD300LF_ENST00000326165 CD300LF Q8TDQ1 CMRF35-like molecule 1 chr17 GO:0048585 Not Cancer Driver No 36 0.124 88 11 0.125 0
CD34 CD34 P28906 Hematopoietic progenitor cell antigen CD34 chr1 GO:0048585 Not Cancer Driver No 65 0.169 221 34 0.154 0
CD3E CD3E P07766 T-cell surface glycoprotein CD3 epsilon chain chr11 GO:0048585 Not Cancer Driver No 28 0.135 72 12 0.167 0
CD44 CD44 P16070 CD44 antigen chr11 GO:0048585 Not Cancer Driver No 75 0.101 542 60 0.111 0
CD46_ENST00000358170 CD46 P15529 Membrane cofactor protein chr1 GO:0048585 Not Cancer Driver No 53 0.135 52 4 0.077 5
CD47 CD47 Q08722 Leukocyte surface antigen CD47 chr3 GO:0048585 Not Cancer Driver No 37 0.115 0 0 0.0 0
CD55_ENST00000367064 CD55 P08174 Complement decay-accelerating factor chr1 GO:0048585 Not Cancer Driver No 45 0.118 128 13 0.102 1
CD59_ENST00000395850 CD59 P13987 CD59 glycoprotein chr11 GO:0048585 Not Cancer Driver No 18 0.141 0 0 0.0 1
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0048585 Census Yes 31 0.105 185 20 0.108 0
CD84 CD84 Q9UIB8 SLAM family member 5 chr1 GO:0048585 Not Cancer Driver No 82 0.238 52 11 0.212 0
CD9 CD9 P21926 CD9 antigen chr12 GO:0048585 Not Cancer Driver No 22 0.096 0 0 0.0 0
CD96 CD96 P40200 T-cell surface protein tactile chr3 GO:0048585 Not Cancer Driver No 132 0.226 165 34 0.206 1
CDK20 CDK20 Q8IZL9 Cyclin-dependent kinase 20 chr9 GO:0048585 Not Cancer Driver No 36 0.104 32 1 0.031 0
CDK6 CDK6 Q00534 Cyclin-dependent kinase 6 chr7 GO:0048585 Census Yes 40 0.123 24 3 0.125 1
CDKN2D_ENST00000335766 CDKN2D P55273 Cyclin-dependent kinase 4 inhibitor D chr19 GO:0048585 Not Cancer Driver No 17 0.102 44 3 0.068 0
CDT1 CDT1 Q9H211 DNA replication factor Cdt1 chr16 GO:0048585 Not Cancer Driver No 60 0.11 377 35 0.093 5
CEACAM1 CEACAM1 P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 chr19 GO:0048585 Not Cancer Driver No 64 0.122 241 25 0.104 0
CELF4 CELF4 Q9BZC1 CUGBP Elav-like family member 4 chr18 GO:0048585 Not Cancer Driver No 107 0.22 253 74 0.292 0
CER1 CER1 O95813 Cerberus chr9 GO:0048585 Not Cancer Driver No 70 0.262 119 27 0.227 0
CERS2_ENST00000368954 CERS2 Q96G23 Ceramide synthase 2 chr1 GO:0048585 Not Cancer Driver No 38 0.1 36 4 0.111 0
CFLAR CFLAR O15519 CASP8 and FADD-like apoptosis regulator chr2 GO:0048585 Not Cancer Driver No 40 0.083 44 2 0.045 0
CHD8_ENST00000643469 CHD8 Q9HCK8 Chromodomain-helicase-DNA-binding protein 8 chr14 GO:0048585 Not Cancer Driver No 328 0.127 1411 148 0.105 0
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 GO:0048585 Census, Compendium Yes 335 0.617 157 130 0.828 13
CHMP6 CHMP6 Q96FZ7 Charged multivesicular body protein 6 chr17 GO:0048585 Not Cancer Driver No 26 0.129 88 16 0.182 0
CHP1 CHP1 Q99653 Calcineurin B homologous protein 1 chr15 GO:0048585 Not Cancer Driver No 27 0.138 70 12 0.171 0
CHRNA10 CHRNA10 Q9GZZ6 Neuronal acetylcholine receptor subunit alpha-10 chr11 GO:0048585 Not Cancer Driver No 65 0.144 34 5 0.147 0
CHRNA9 CHRNA9 Q9UGM1 Neuronal acetylcholine receptor subunit alpha-9 chr4 GO:0048585 Not Cancer Driver No 76 0.159 23 6 0.261 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0048585 Not Cancer Driver No 24 0.126 6 1 0.167 0
CILP CILP O75339 Cartilage intermediate layer protein 1 chr15 GO:0048585 Not Cancer Driver No 206 0.174 278 44 0.158 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 GO:0048585 Not Cancer Driver No 284 0.14 1017 160 0.157 3
CLASP1_ENST00000646274 CLASP1 Q7Z460 CLIP-associating protein 1 chr2 GO:0048585 Not Cancer Driver No 163 0.106 642 70 0.109 0
CLASP2 CLASP2 O75122 CLIP-associating protein 2 chr3 GO:0048585 Not Cancer Driver No 158 0.122 676 94 0.139 0
CLDN19 CLDN19 Q8N6F1 Claudin-19 chr1 GO:0048585 Not Cancer Driver No 27 0.121 20 2 0.1 3
CLDN3 CLDN3 O15551 Claudin-3 chr7 GO:0048585 Not Cancer Driver No 12 0.055 0 0 0.0 0
CLEC12B CLEC12B Q2HXU8 C-type lectin domain family 12 member B chr12 GO:0048585 Not Cancer Driver No 34 0.123 57 8 0.14 0
CLEC4G CLEC4G Q6UXB4 C-type lectin domain family 4 member G chr19 GO:0048585 Not Cancer Driver No 40 0.137 35 4 0.114 0
CLOCK CLOCK O15516 Circadian locomoter output cycles protein kaput chr4 GO:0048585 Not Cancer Driver No 83 0.098 458 38 0.083 0
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0048585 Not Cancer Driver No 69 0.154 156 27 0.173 0
CNKSR3 CNKSR3 Q6P9H4 Connector enhancer of kinase suppressor of ras 3 chr6 GO:0048585 Not Cancer Driver No 72 0.13 269 43 0.16 0
CNOT1 CNOT1 A5YKK6 CCR4-NOT transcription complex subunit 1 chr16 GO:0048585 Not Cancer Driver No 346 0.146 464 56 0.121 12
CNOT2 CNOT2 Q9NZN8 CCR4-NOT transcription complex subunit 2 chr12 GO:0048585 Not Cancer Driver No 84 0.156 354 66 0.186 0
CNOT7 CNOT7 Q9UIV1 CCR4-NOT transcription complex subunit 7 chr8 GO:0048585 Not Cancer Driver No 31 0.109 21 1 0.048 0
CNOT9_ENST00000273064 CNOT9 Q92600 CCR4-NOT transcription complex subunit 9 chr2 GO:0048585 Compendium Yes 42 0.14 30 0 0.0 0
COL2A1 COL2A1 P02458 Collagen alpha-1(II) chain chr12 GO:0048585 Census Yes 258 0.174 1215 207 0.17 64
COL3A1 COL3A1 P02461 Collagen alpha-1(III) chain chr2 GO:0048585 Census Yes 402 0.274 1182 337 0.285 103
CORO1B CORO1B Q9BR76 Coronin-1B chr11 GO:0048585 Not Cancer Driver No 41 0.084 138 10 0.072 0
CPB2_ENST00000645658 CPB2 Q96IY4 Carboxypeptidase B2 chr13 GO:0048585 Not Cancer Driver No 59 0.139 2 0 0.0 0
CPNE1_ENST00000352393 CPNE1 Q99829 Copine-1 chr20 GO:0048585 Not Cancer Driver No 74 0.138 80 7 0.087 0
CR1L CR1L Q2VPA4 Complement component receptor 1-like protein chr1 GO:0048585 Not Cancer Driver No 121 0.213 55 14 0.255 0
CR1_ENST00000367053 CR1 P17927 Complement receptor type 1 chr1 GO:0048585 Compendium Yes 383 0.188 151 42 0.278 0
CR2_ENST00000367058 CR2 P20023 Complement receptor type 2 chr1 GO:0048585 Not Cancer Driver No 273 0.264 85 28 0.329 0
CREB3 CREB3 O43889 Cyclic AMP-responsive element-binding protein 3 chr9 GO:0048585 Not Cancer Driver No 33 0.089 168 11 0.065 0
CREB3L1 CREB3L1 Q96BA8 Cyclic AMP-responsive element-binding protein 3-like protein 1 chr11 GO:0048585 Census Yes 68 0.131 372 50 0.134 0
CRHBP CRHBP P24387 Corticotropin-releasing factor-binding protein chr5 GO:0048585 Not Cancer Driver No 61 0.189 0 0 0.0 0
CRK CRK P46108 Adapter molecule crk chr17 GO:0048585 Not Cancer Driver No 30 0.099 197 23 0.117 0
CRTC3 CRTC3 Q6UUV7 CREB-regulated transcription coactivator 3 chr15 GO:0048585 Census Yes 70 0.113 608 68 0.112 0
CRY1 CRY1 Q16526 Cryptochrome-1 chr12 GO:0048585 Not Cancer Driver No 76 0.13 91 5 0.055 0
CRY2_ENST00000616080 CRY2 Q49AN0 Cryptochrome-2 chr11 GO:0048585 Not Cancer Driver No 72 0.121 100 12 0.12 0
CRYBA1 CRYBA1 P05813 Beta-crystallin A3 chr17 GO:0048585 Not Cancer Driver No 29 0.135 52 11 0.212 0
CSF2 CSF2 P04141 Granulocyte-macrophage colony-stimulating factor chr5 GO:0048585 Not Cancer Driver No 11 0.076 34 3 0.088 0
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 GO:0048585 Not Cancer Driver No 41 0.091 18 1 0.056 0
CST7 CST7 O76096 Cystatin-F chr20 GO:0048585 Not Cancer Driver No 12 0.083 15 2 0.133 0
CTLA4 CTLA4 P16410 Cytotoxic T-lymphocyte protein 4 chr2 GO:0048585 Not Cancer Driver No 37 0.166 3 0 0.0 1
CTNNA1 CTNNA1 P35221 Catenin alpha-1 chr5 GO:0048585 Census Yes 126 0.139 268 35 0.131 4
CTNNA2 CTNNA2 P26232 Catenin alpha-2 chr2 GO:0048585 Census Yes 387 0.406 307 130 0.423 0
CUL3 CUL3 Q13618 Cullin-3 chr2 GO:0048585 Census, Compendium Yes 123 0.16 167 23 0.138 3
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0048585 Not Cancer Driver No 66 0.166 259 44 0.17 0
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:0048585 Not Cancer Driver No 16 0.172 0 0 0.0 0
CXCL13 CXCL13 O43927 C-X-C motif chemokine 13 chr4 GO:0048585 Not Cancer Driver No 11 0.101 0 0 0.0 0
CXCL8 CXCL8 P10145 Interleukin-8 chr4 GO:0048585 Not Cancer Driver No 17 0.172 0 0 0.0 0
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 GO:0048585 Census, Compendium Yes 116 0.121 213 31 0.146 3
CYP19A1_ENST00000396404 CYP19A1 P11511 Aromatase chr15 GO:0048585 Not Cancer Driver No 91 0.181 2 1 0.5 5
CYP26A1 CYP26A1 O43174 Cytochrome P450 26A1 chr10 GO:0048585 Not Cancer Driver No 84 0.169 9 1 0.111 0
CYP26B1 CYP26B1 Q9NR63 Cytochrome P450 26B1 chr2 GO:0048585 Not Cancer Driver No 113 0.221 10 3 0.3 2
CYP26C1 CYP26C1 Q6V0L0 Cytochrome P450 26C1 chr10 GO:0048585 Not Cancer Driver No 32 0.061 56 6 0.107 0
CYP7B1 CYP7B1 O75881 Cytochrome P450 7B1 chr8 GO:0048585 Not Cancer Driver No 133 0.263 0 0 0.0 11
CYREN CYREN Q9BWK5 Cell cycle regulator of non-homologous end joining chr7 GO:0048585 Not Cancer Driver No 24 0.153 128 19 0.148 0
DAB1_ENST00000371231 DAB1 O75553 Disabled homolog 1 chr1 GO:0048585 Not Cancer Driver No 200 0.34 393 143 0.364 0
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0048585 Not Cancer Driver No 144 0.187 680 125 0.184 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0048585 Not Cancer Driver No 131 0.11 681 68 0.1 0
DACT1 DACT1 Q9NYF0 Dapper homolog 1 chr14 GO:0048585 Not Cancer Driver No 163 0.195 598 127 0.212 1
DACT2 DACT2 Q5SW24 Dapper homolog 2 chr6 GO:0048585 Not Cancer Driver No 35 0.045 655 30 0.046 0
DAG1_ENST00000515359 DAG1 Q14118 Dystroglycan 1 chr3 GO:0048585 Not Cancer Driver No 102 0.114 485 61 0.126 4
DAND5 DAND5 Q8N907 DAN domain family member 5 chr19 GO:0048585 Not Cancer Driver No 32 0.169 26 3 0.115 0
DCN DCN P07585 Decorin chr12 GO:0048585 Not Cancer Driver No 96 0.267 81 26 0.321 0
DCST1 DCST1 Q5T197 E3 ubiquitin-protein ligase DCST1 chr1 GO:0048585 Not Cancer Driver No 108 0.153 51 9 0.176 0
DDAH1 DDAH1 O94760 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 chr1 GO:0048585 Not Cancer Driver No 28 0.098 44 3 0.068 0
DDIAS DDIAS Q8IXT1 DNA damage-induced apoptosis suppressor protein chr11 GO:0048585 Not Cancer Driver No 125 0.125 370 59 0.159 0
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 GO:0048585 Census Yes 29 0.172 160 27 0.169 0
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 GO:0048585 Not Cancer Driver No 34 0.108 181 23 0.127 0
DDT_ENST00000350608 DDT P30046 D-dopachrome decarboxylase chr22 GO:0048585 Not Cancer Driver No 4 0.034 0 0 0.0 0
DDX39B_ENST00000458640 DDX39B Q13838 Spliceosome RNA helicase DDX39B chr6 GO:0048585 Not Cancer Driver No 49 0.114 34 8 0.235 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:0048585 Census, Compendium Yes 133 0.201 301 47 0.156 18
DEFB114 DEFB114 Q30KQ6 Beta-defensin 114 chr6 GO:0048585 Not Cancer Driver No 31 0.449 0 0 0.0 0
DEPDC5_ENST00000382112 DEPDC5 O75140 GATOR complex protein DEPDC5 chr22 GO:0048585 Not Cancer Driver No 226 0.141 575 91 0.158 7
DEPTOR DEPTOR Q8TB45 DEP domain-containing mTOR-interacting protein chr8 GO:0048585 Not Cancer Driver No 57 0.139 125 12 0.096 0
DGKD DGKD Q16760 Diacylglycerol kinase delta chr2 GO:0048585 Not Cancer Driver No 160 0.132 441 60 0.136 0
DGKG DGKG P49619 Diacylglycerol kinase gamma chr3 GO:0048585 Not Cancer Driver No 160 0.202 182 43 0.236 0
DGKZ_ENST00000456247 DGKZ Q13574 Diacylglycerol kinase zeta chr11 GO:0048585 Not Cancer Driver No 87 0.094 410 42 0.102 0
DHRS3 DHRS3 O75911 Short-chain dehydrogenase/reductase 3 chr1 GO:0048585 Not Cancer Driver No 33 0.109 0 0 0.0 0
DHX58 DHX58 Q96C10 ATP-dependent RNA helicase DHX58 chr17 GO:0048585 Not Cancer Driver No 62 0.091 84 8 0.095 0
DKK1 DKK1 O94907 Dickkopf-related protein 1 chr10 GO:0048585 Not Cancer Driver No 58 0.218 47 8 0.17 0
DKK3_ENST00000326932 DKK3 Q9UBP4 Dickkopf-related protein 3 chr11 GO:0048585 Not Cancer Driver No 44 0.126 161 22 0.137 0
DLC1 DLC1 Q96QB1 Rho GTPase-activating protein 7 chr8 GO:0048585 Not Cancer Driver No 331 0.217 922 237 0.257 0
DLG1_ENST00000419354 DLG1 Q12959 Disks large homolog 1 chr3 GO:0048585 Not Cancer Driver No 120 0.133 460 67 0.146 0
DLG5 DLG5 Q8TDM6 Disks large homolog 5 chr10 GO:0048585 Not Cancer Driver No 230 0.12 1119 135 0.121 0
DLX1 DLX1 P56177 Homeobox protein DLX-1 chr2 GO:0048585 Not Cancer Driver No 25 0.098 183 21 0.115 0
DNAJA1 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 GO:0048585 Not Cancer Driver No 37 0.093 153 16 0.105 0
DNAJB9 DNAJB9 Q9UBS3 DnaJ homolog subfamily B member 9 chr7 GO:0048585 Not Cancer Driver No 30 0.135 107 15 0.14 0
DPP4 DPP4 P27487 Dipeptidyl peptidase 4 chr2 GO:0048585 Not Cancer Driver No 151 0.197 8 1 0.125 0
DRD1 DRD1 P21728 D(1A) dopamine receptor chr5 GO:0048585 Not Cancer Driver No 73 0.164 30 4 0.133 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0048585 Not Cancer Driver No 127 0.287 124 45 0.363 0
DRD3_ENST00000460779 DRD3 P35462 D(3) dopamine receptor chr3 GO:0048585 Not Cancer Driver No 88 0.22 45 17 0.378 0
DUPD1 DUSP29 Q68J44 Dual specificity phosphatase 29 chr10 GO:0048585 Not Cancer Driver No 47 0.214 55 7 0.127 0
DUSP1 DUSP1 P28562 Dual specificity protein phosphatase 1 chr5 GO:0048585 Not Cancer Driver No 31 0.084 7 0 0.0 0
DUSP10 DUSP10 Q9Y6W6 Dual specificity protein phosphatase 10 chr1 GO:0048585 Not Cancer Driver No 81 0.168 135 24 0.178 0
DUSP16 DUSP16 Q9BY84 Dual specificity protein phosphatase 16 chr12 GO:0048585 Compendium Yes 70 0.105 273 34 0.125 0
DUSP19 DUSP19 Q8WTR2 Dual specificity protein phosphatase 19 chr2 GO:0048585 Not Cancer Driver No 34 0.157 15 5 0.333 0
DUSP22_ENST00000344450 DUSP22 Q9NRW4 Dual specificity protein phosphatase 22 chr6 GO:0048585 Not Cancer Driver No 84 0.457 0 0 0.0 0
DUSP26 DUSP26 Q9BV47 Dual specificity protein phosphatase 26 chr8 GO:0048585 Not Cancer Driver No 56 0.265 14 6 0.429 0
DUSP3 DUSP3 P51452 Dual specificity protein phosphatase 3 chr17 GO:0048585 Not Cancer Driver No 21 0.114 4 1 0.25 0
DUSP4 DUSP4 Q13115 Dual specificity protein phosphatase 4 chr8 GO:0048585 Not Cancer Driver No 43 0.109 63 9 0.143 0
DUSP6 DUSP6 Q16828 Dual specificity protein phosphatase 6 chr12 GO:0048585 Not Cancer Driver No 43 0.113 39 3 0.077 4
DUSP9 DUSP9 Q99956 Dual specificity protein phosphatase 9 chrX GO:0048585 Not Cancer Driver No 40 0.104 109 12 0.11 0
DVL1 DVL1 O14640 Segment polarity protein dishevelled homolog DVL-1 chr1 GO:0048585 Not Cancer Driver No 73 0.105 434 38 0.088 0
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 GO:0048585 Not Cancer Driver No 135 0.177 447 73 0.163 0
DYRK2 DYRK2 Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 chr12 GO:0048585 Not Cancer Driver No 77 0.128 294 39 0.133 0
DYRK3 DYRK3 O43781 Dual specificity tyrosine-phosphorylation-regulated kinase 3 chr1 GO:0048585 Not Cancer Driver No 87 0.148 193 20 0.104 0
ECM1_ENST00000369047 ECM1 Q16610 Extracellular matrix protein 1 chr1 GO:0048585 Not Cancer Driver No 91 0.169 219 28 0.128 1
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0048585 Census, Compendium Yes 444 0.367 223 35 0.157 1
EIF3A EIF3A Q14152 Eukaryotic translation initiation factor 3 subunit A chr10 GO:0048585 Not Cancer Driver No 181 0.131 835 130 0.156 0
EIF4A3 EIF4A3 P38919 Eukaryotic initiation factor 4A-III chr17 GO:0048585 Not Cancer Driver No 50 0.122 57 6 0.105 1
ELANE_ENST00000263621 ELANE P08246 Neutrophil elastase chr19 GO:0048585 Not Cancer Driver No 39 0.146 18 3 0.167 89
ELF1 ELF1 P32519 ETS-related transcription factor Elf-1 chr13 GO:0048585 Not Cancer Driver No 78 0.126 469 62 0.132 0
ELL3 ELL3 Q9HB65 RNA polymerase II elongation factor ELL3 chr15 GO:0048585 Not Cancer Driver No 50 0.126 186 13 0.07 0
EMILIN1 EMILIN1 Q9Y6C2 EMILIN-1 chr2 GO:0048585 Not Cancer Driver No 125 0.123 669 69 0.103 0
ENO1 ENO1 P06733 Alpha-enolase chr1 GO:0048585 Not Cancer Driver No 51 0.118 21 2 0.095 0
ENPP1 ENPP1 P22413 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 chr6 GO:0048585 Not Cancer Driver No 148 0.16 101 5 0.05 33
ENPP3_ENST00000357639 ENPP3 O14638 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 chr6 GO:0048585 Not Cancer Driver No 146 0.167 57 12 0.211 0
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 GO:0048585 Compendium Yes 171 0.175 187 39 0.209 3
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0048585 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0048585 Not Cancer Driver No 186 0.176 119 17 0.143 7
EPN2 EPN2 O95208 Epsin-2 chr17 GO:0048585 Not Cancer Driver No 73 0.114 543 61 0.112 0
EPO EPO P01588 Erythropoietin chr7 GO:0048585 Not Cancer Driver No 27 0.14 9 1 0.111 1
EPPK1 EPPK1 P58107 Epiplakin chr8 GO:0048585 Not Cancer Driver No 417 0.082 1336 67 0.05 0
ERBIN_ENST00000284037 ERBIN Q96RT1 Erbin chr5 GO:0048585 Not Cancer Driver No 167 0.118 967 118 0.122 0
ERCC1_ENST00000589165 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0048585 Not Cancer Driver No 42 0.141 105 14 0.133 1
ERCC4 ERCC4 Q92889 DNA repair endonuclease XPF chr16 GO:0048585 Census Yes 120 0.131 225 27 0.12 15
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0048585 Not Cancer Driver No 211 0.141 829 117 0.141 9
ERRFI1 ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 chr1 GO:0048585 Not Cancer Driver No 55 0.119 297 37 0.125 0
EYA1_ENST00000647540 EYA1 Q99502 Eyes absent homolog 1 chr8 GO:0048585 Not Cancer Driver No 168 0.284 341 99 0.29 15
EYA2 EYA2 O00167 Eyes absent homolog 2 chr20 GO:0048585 Not Cancer Driver No 107 0.199 204 50 0.245 0
EYA3 EYA3 Q99504 Eyes absent homolog 3 chr1 GO:0048585 Not Cancer Driver No 58 0.101 310 40 0.129 0
EYA4_ENST00000367895 EYA4 O95677 Eyes absent homolog 4 chr6 GO:0048585 Not Cancer Driver No 183 0.286 337 108 0.32 2
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:0048585 Census, Compendium Yes 120 0.161 284 44 0.155 11
EZR EZR P15311 Ezrin chr6 GO:0048585 Census Yes 66 0.113 295 35 0.119 0
F11 F11 P03951 Coagulation factor XI chr4 GO:0048585 Not Cancer Driver No 108 0.173 1 0 0.0 58
F12 F12 P00748 Coagulation factor XII chr5 GO:0048585 Not Cancer Driver No 53 0.086 104 9 0.087 13
F2 F2 P00734 Prothrombin chr11 GO:0048585 Not Cancer Driver No 115 0.185 97 25 0.258 10
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0048585 Not Cancer Driver No 55 0.139 7 2 0.286 0
FAIM2 FAIM2 Q9BWQ8 Protein lifeguard 2 chr12 GO:0048585 Not Cancer Driver No 37 0.117 54 11 0.204 0
FAIM_ENST00000393035 FAIM Q9NVQ4 Fas apoptotic inhibitory molecule 1 chr3 GO:0048585 Not Cancer Driver No 20 0.112 1 0 0.0 0
FAM129B NIBAN2 Q96TA1 Protein Niban 2 chr9 GO:0048585 Not Cancer Driver No 99 0.133 206 20 0.097 0
FAM19A3_ENST00000361886 TAFA3 Q7Z5A8 Chemokine-like protein TAFA-3 chr1 GO:0048585 Not Cancer Driver No 17 0.128 6 0 0.0 0
FAM19A5 TAFA5 Q7Z5A7 Chemokine-like protein TAFA-5 chr22 GO:0048585 Not Cancer Driver No 31 0.235 27 6 0.222 0
FAM3A_ENST00000447601 FAM3A P98173 Protein FAM3A chrX GO:0048585 Not Cancer Driver No 27 0.117 48 9 0.188 0
FAM89B FAM89B Q8N5H3 Leucine repeat adapter protein 25 chr11 GO:0048585 Not Cancer Driver No 14 0.074 108 11 0.102 0
FBLN1 FBLN1 P23142 Fibulin-1 chr22 GO:0048585 Compendium Yes 122 0.174 22 3 0.136 0
FBN1 FBN1 P35555 Fibrillin-1 chr15 GO:0048585 Not Cancer Driver No 466 0.162 110 16 0.145 360
FBN2_ENST00000262464 FBN2 P35556 Fibrillin-2 chr5 GO:0048585 Compendium Yes 607 0.208 135 24 0.178 30
FBXO5 FBXO5 Q9UKT4 F-box only protein 5 chr6 GO:0048585 Not Cancer Driver No 48 0.107 113 13 0.115 0
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 GO:0048585 Census, Compendium Yes 322 0.455 230 38 0.165 0
FCGR2B FCGR2B P31994 Low affinity immunoglobulin gamma Fc region receptor II-b chr1 GO:0048585 Census Yes 51 0.165 99 30 0.303 0
FCRL3_ENST00000368184 FCRL3 Q96P31 Fc receptor-like protein 3 chr1 GO:0048585 Not Cancer Driver No 193 0.263 217 44 0.203 0
FCRLB FCRLB Q6BAA4 Fc receptor-like B chr1 GO:0048585 Not Cancer Driver No 51 0.12 147 14 0.095 0
FER FER P16591 Tyrosine-protein kinase Fer chr5 GO:0048585 Not Cancer Driver No 114 0.139 145 21 0.145 0
FGA FGA P02671 Fibrinogen alpha chain chr4 GO:0048585 Not Cancer Driver No 245 0.283 522 149 0.285 7
FGB FGB P02675 Fibrinogen beta chain chr4 GO:0048585 Not Cancer Driver No 89 0.181 143 29 0.203 7
FGF10 FGF10 O15520 Fibroblast growth factor 10 chr5 GO:0048585 Not Cancer Driver No 56 0.269 34 11 0.324 2
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0048585 Not Cancer Driver No 18 0.062 183 5 0.027 0
FGG FGG P02679 Fibrinogen gamma chain chr4 GO:0048585 Not Cancer Driver No 81 0.179 53 8 0.151 8
FGL2 FGL2 Q14314 Fibroleukin chr7 GO:0048585 Not Cancer Driver No 71 0.162 70 12 0.171 0
FGR_ENST00000374004 FGR P09769 Tyrosine-protein kinase Fgr chr1 GO:0048585 Not Cancer Driver No 85 0.161 52 8 0.154 0
FHL2_ENST00000408995 FHL2 Q14192 Four and a half LIM domains protein 2 chr2 GO:0048585 Not Cancer Driver No 30 0.108 0 0 0.0 0
FKBP1B FKBP1B P68106 Peptidyl-prolyl cis-trans isomerase FKBP1B chr2 GO:0048585 Not Cancer Driver No 10 0.093 58 4 0.069 0
FKTN_ENST00000602661 FKTN O75072 Ribitol-5-phosphate transferase FKTN chr9 GO:0048585 Not Cancer Driver No 51 0.111 0 0 0.0 10
FLCN FLCN Q8NFG4 Folliculin chr17 GO:0048585 Census, Compendium Yes 59 0.102 157 19 0.121 5
FOXA2_ENST00000377115 FOXA2 Q9Y261 Hepatocyte nuclear factor 3-beta chr20 GO:0048585 Compendium Yes 70 0.153 258 34 0.132 0
FOXF1 FOXF1 Q12946 Forkhead box protein F1 chr16 GO:0048585 Not Cancer Driver No 56 0.148 194 20 0.103 20
FOXH1 FOXH1 O75593 Forkhead box protein H1 chr8 GO:0048585 Not Cancer Driver No 47 0.129 215 25 0.116 0
FOXJ1 FOXJ1 Q92949 Forkhead box protein J1 chr17 GO:0048585 Not Cancer Driver No 25 0.059 279 18 0.065 0
FOXM1_ENST00000359843 FOXM1 Q08050 Forkhead box protein M1 chr12 GO:0048585 Not Cancer Driver No 97 0.127 601 73 0.121 0
FOXO1 FOXO1 Q12778 Forkhead box protein O1 chr13 GO:0048585 Census, Compendium Yes 81 0.124 584 75 0.128 0
FOXP1_ENST00000318789 FOXP1 Q9H334 Forkhead box protein P1 chr3 GO:0048585 Census, Compendium Yes 109 0.161 448 71 0.158 3
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0048585 Not Cancer Driver No 38 0.088 186 16 0.086 10
FST FST P19883 Follistatin chr5 GO:0048585 Not Cancer Driver No 50 0.145 20 7 0.35 0
FSTL3 FSTL3 O95633 Follistatin-related protein 3 chr19 GO:0048585 Census Yes 17 0.065 28 2 0.071 0
FSTL4 FSTL4 Q6MZW2 Follistatin-related protein 4 chr5 GO:0048585 Not Cancer Driver No 134 0.159 96 12 0.125 0
FURIN_ENST00000610579 FURIN P09958 Furin chr15 GO:0048585 Not Cancer Driver No 93 0.117 283 35 0.124 0
FUZ FUZ Q9BT04 Protein fuzzy homolog chr19 GO:0048585 Not Cancer Driver No 38 0.091 43 4 0.093 0
FXN FXN Q16595 Frataxin, mitochondrial chr9 GO:0048585 Not Cancer Driver No 16 0.076 73 0 0.0 8
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0048585 Not Cancer Driver No 92 0.171 70 13 0.186 0
FZD9 FZD9 O00144 Frizzled-9 chr7 GO:0048585 Not Cancer Driver No 55 0.093 61 0 0.0 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0048585 Not Cancer Driver No 82 0.121 42 6 0.143 0
GATA1 GATA1 P15976 Erythroid transcription factor chrX GO:0048585 Census, Compendium Yes 68 0.165 242 41 0.169 5
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0048585 Census, Compendium Yes 111 0.251 364 87 0.239 2
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0048585 Not Cancer Driver No 74 0.138 38 5 0.132 171
GBP1 GBP1 P32455 Guanylate-binding protein 1 chr1 GO:0048585 Not Cancer Driver No 92 0.155 166 27 0.163 0
GBP7 GBP7 Q8N8V2 Guanylate-binding protein 7 chr1 GO:0048585 Not Cancer Driver No 88 0.138 93 8 0.086 0
GCLC GCLC P48506 Glutamate--cysteine ligase catalytic subunit chr6 GO:0048585 Not Cancer Driver No 73 0.115 167 18 0.108 3
GDF15 GDF15 Q99988 Growth/differentiation factor 15 chr19 GO:0048585 Not Cancer Driver No 39 0.127 143 20 0.14 0
GDNF_ENST00000326524 GDNF P39905 Glial cell line-derived neurotrophic factor chr5 GO:0048585 Not Cancer Driver No 47 0.223 83 18 0.217 2
GFER GFER P55789 FAD-linked sulfhydryl oxidase ALR chr16 GO:0048585 Not Cancer Driver No 10 0.049 97 4 0.041 1
GFRAL GFRAL Q6UXV0 GDNF family receptor alpha-like chr6 GO:0048585 Not Cancer Driver No 176 0.447 5 2 0.4 0
GGT7 GGT7 Q9UJ14 Glutathione hydrolase 7 chr20 GO:0048585 Not Cancer Driver No 77 0.116 170 14 0.082 0
GHITM GHITM Q9H3K2 Growth hormone-inducible transmembrane protein chr10 GO:0048585 Not Cancer Driver No 50 0.145 8 0 0.0 0
GHSR GHSR Q92847 Growth hormone secretagogue receptor type 1 chr3 GO:0048585 Not Cancer Driver No 85 0.232 4 0 0.0 2
GIPR GIPR P48546 Gastric inhibitory polypeptide receptor chr19 GO:0048585 Not Cancer Driver No 45 0.097 41 0 0.0 0
GIT1_ENST00000225394 GIT1 Q9Y2X7 ARF GTPase-activating protein GIT1 chr17 GO:0048585 Not Cancer Driver No 67 0.088 434 42 0.097 0
GLI1 GLI1 P08151 Zinc finger protein GLI1 chr12 GO:0048585 Census, Compendium Yes 206 0.186 1015 184 0.181 0
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0048585 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GLIS2 GLIS2 Q9BZE0 Zinc finger protein GLIS2 chr16 GO:0048585 Not Cancer Driver No 42 0.08 300 25 0.083 0
GNAI2 GNAI2 P04899 Guanine nucleotide-binding protein G(i) subunit alpha-2 chr3 GO:0048585 Compendium Yes 50 0.141 24 0 0.0 0
GP1BA GP1BA P07359 Platelet glycoprotein Ib alpha chain chr17 GO:0048585 Not Cancer Driver No 65 0.1 247 18 0.073 9
GPATCH3 GPATCH3 Q96I76 G patch domain-containing protein 3 chr1 GO:0048585 Not Cancer Driver No 64 0.122 354 48 0.136 0
GPC1 GPC1 P35052 Glypican-1 chr2 GO:0048585 Not Cancer Driver No 58 0.104 166 14 0.084 0
GPC3_ENST00000370818 GPC3 P51654 Glypican-3 chrX GO:0048585 Census Yes 89 0.153 86 11 0.128 1
GPD1L GPD1L Q8N335 Glycerol-3-phosphate dehydrogenase 1-like protein chr3 GO:0048585 Not Cancer Driver No 40 0.114 13 1 0.077 0
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0048585 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPR108 GPR108 Q9NPR9 Protein GPR108 chr19 GO:0048585 Not Cancer Driver No 64 0.118 56 12 0.214 0
GPR161_ENST00000367835 GPR161 Q8N6U8 G-protein coupled receptor 161 chr1 GO:0048585 Not Cancer Driver No 84 0.159 108 16 0.148 0
GPR18_ENST00000397470 GPR18 Q14330 N-arachidonyl glycine receptor chr13 GO:0048585 Not Cancer Driver No 36 0.109 0 0 0.0 0
GPR21 GPR21 Q99679 Probable G-protein coupled receptor 21 chr9 GO:0048585 Not Cancer Driver No 39 0.112 2 0 0.0 0
GPR37 GPR37 O15354 Prosaposin receptor GPR37 chr7 GO:0048585 Not Cancer Driver No 124 0.202 200 42 0.21 0
GPR37L1 GPR37L1 O60883 G-protein coupled receptor 37-like 1 chr1 GO:0048585 Not Cancer Driver No 62 0.129 81 8 0.099 0
GPRASP1_ENST00000415986 GPRASP1 Q5JY77 G-protein coupled receptor-associated sorting protein 1 chrX GO:0048585 Not Cancer Driver No 217 0.156 918 133 0.145 0
GPRC5A GPRC5A Q8NFJ5 Retinoic acid-induced protein 3 chr12 GO:0048585 Not Cancer Driver No 43 0.12 19 4 0.211 0
GPS2 GPS2 Q13227 G protein pathway suppressor 2 chr17 GO:0048585 Not Cancer Driver No 29 0.089 319 26 0.082 0
GPX1_ENST00000620890 GPX1 P07203 Glutathione peroxidase 1 chr3 GO:0048585 Not Cancer Driver No 38 0.187 12 1 0.083 0
GRAMD4_ENST00000361034 GRAMD4 Q6IC98 GRAM domain-containing protein 4 chr22 GO:0048585 Not Cancer Driver No 79 0.137 165 27 0.164 0
GRB10_ENST00000401949 GRB10 Q13322 Growth factor receptor-bound protein 10 chr7 GO:0048585 Not Cancer Driver No 94 0.158 220 38 0.173 0
GRB14 GRB14 Q14449 Growth factor receptor-bound protein 14 chr2 GO:0048585 Not Cancer Driver No 83 0.154 117 11 0.094 0
GRB7_ENST00000394209 GRB7 Q14451 Growth factor receptor-bound protein 7 chr17 GO:0048585 Not Cancer Driver No 84 0.158 134 27 0.201 0
GREM1 GREM1 O60565 Gremlin-1 chr15 GO:0048585 Not Cancer Driver No 25 0.136 77 12 0.156 0
GREM2 GREM2 Q9H772 Gremlin-2 chr1 GO:0048585 Not Cancer Driver No 54 0.321 22 9 0.409 3
GRID2 GRID2 O43424 Glutamate receptor ionotropic, delta-2 chr4 GO:0048585 Not Cancer Driver No 350 0.348 155 35 0.226 3
GRIN3A GRIN3A Q8TCU5 Glutamate receptor ionotropic, NMDA 3A chr9 GO:0048585 Not Cancer Driver No 308 0.276 179 22 0.123 0
GRINA_ENST00000395068 GRINA Q7Z429 Protein lifeguard 1 chr8 GO:0048585 Not Cancer Driver No 39 0.105 150 15 0.1 0
GRK2 GRK2 P25098 Beta-adrenergic receptor kinase 1 chr11 GO:0048585 Not Cancer Driver No 77 0.112 87 8 0.092 0
GRK3 GRK3 P35626 Beta-adrenergic receptor kinase 2 chr22 GO:0048585 Not Cancer Driver No 87 0.126 78 8 0.103 0
GRM5 GRM5 P41594 Metabotropic glutamate receptor 5 chr11 GO:0048585 Not Cancer Driver No 312 0.257 323 51 0.158 0
GRN GRN P28799 Progranulin chr17 GO:0048585 Not Cancer Driver No 76 0.128 29 6 0.207 1
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0048585 Not Cancer Driver No 55 0.114 180 8 0.044 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0048585 Not Cancer Driver No 56 0.133 146 13 0.089 0
GSTP1_ENST00000642444 GSTP1 P09211 Glutathione S-transferase P chr11 GO:0048585 Not Cancer Driver No 32 0.152 0 0 0.0 0
HAVCR2 HAVCR2 Q8TDQ0 Hepatitis A virus cellular receptor 2 chr5 GO:0048585 Not Cancer Driver No 69 0.229 17 2 0.118 3
HCK_ENST00000534862 HCK P08631 Tyrosine-protein kinase HCK chr20 GO:0048585 Not Cancer Driver No 112 0.213 124 25 0.202 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 GO:0048585 Not Cancer Driver No 47 0.098 135 10 0.074 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 GO:0048585 Not Cancer Driver No 65 0.152 61 8 0.131 0
HDAC7_ENST00000427332 HDAC7 Q8WUI4 Histone deacetylase 7 chr12 GO:0048585 Not Cancer Driver No 91 0.096 570 50 0.088 0
HEG1 HEG1 Q9ULI3 Protein HEG homolog 1 chr3 GO:0048585 Not Cancer Driver No 173 0.125 974 135 0.139 0
HERC4 HERC4 Q5GLZ8 Probable E3 ubiquitin-protein ligase HERC4 chr10 GO:0048585 Not Cancer Driver No 111 0.105 40 2 0.05 0
HERPUD1 HERPUD1 Q15011 Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein chr16 GO:0048585 Census Yes 38 0.097 248 17 0.069 0
HEYL HEYL Q9NQ87 Hairy/enhancer-of-split related with YRPW motif-like protein chr1 GO:0048585 Not Cancer Driver No 44 0.134 198 19 0.096 0
HFE HFE Q30201 Hereditary hemochromatosis protein chr6 GO:0048585 Not Cancer Driver No 55 0.158 27 2 0.074 11
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0048585 Compendium Yes 233 0.32 43 16 0.372 0
HGS HGS O14964 Hepatocyte growth factor-regulated tyrosine kinase substrate chr17 GO:0048585 Not Cancer Driver No 109 0.14 528 74 0.14 0
HHEX HHEX Q03014 Hematopoietically-expressed homeobox protein HHEX chr10 GO:0048585 Not Cancer Driver No 23 0.085 193 21 0.109 0
HHIP HHIP Q96QV1 Hedgehog-interacting protein chr4 GO:0048585 Not Cancer Driver No 150 0.214 73 34 0.466 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0048585 Census Yes 118 0.143 435 51 0.117 0
HIPK3 HIPK3 Q9H422 Homeodomain-interacting protein kinase 3 chr11 GO:0048585 Not Cancer Driver No 128 0.105 559 51 0.091 0
HIST1H2BJ_ENST00000339812 H2BC11 P06899 Histone H2B type 1-J chr6 GO:0048585 Not Cancer Driver No 22 0.175 75 13 0.173 0
HLA-A_ENST00000376809 HLA-A P04439 HLA class I histocompatibility antigen, A alpha chain chr6 GO:0048585 Census, Compendium Yes 128 0.351 125 60 0.48 0
HLA-B HLA-B P01889 HLA class I histocompatibility antigen, B alpha chain chr6 GO:0048585 Compendium Yes 78 0.215 169 34 0.201 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0048585 Not Cancer Driver No 48 0.18 12 1 0.083 0
HLA-E HLA-E P13747 HLA class I histocompatibility antigen, alpha chain E chr6 GO:0048585 Not Cancer Driver No 63 0.176 138 39 0.283 0
HLA-F_ENST00000376861 HLA-F P30511 HLA class I histocompatibility antigen, alpha chain F chr6 GO:0048585 Not Cancer Driver No 43 0.124 115 22 0.191 0
HLA-G_ENST00000360323 HLA-G P17693 HLA class I histocompatibility antigen, alpha chain G chr6 GO:0048585 Not Cancer Driver No 94 0.278 85 22 0.259 0
HLX HLX Q14774 H2.0-like homeobox protein chr1 GO:0048585 Not Cancer Driver No 107 0.219 412 98 0.238 0
HMGA2_ENST00000403681 HMGA2 P52926 High mobility group protein HMGI-C chr12 GO:0048585 Census Yes 12 0.11 109 12 0.11 0
HMGB2 HMGB2 P26583 High mobility group protein B2 chr4 GO:0048585 Not Cancer Driver No 38 0.182 207 38 0.184 0
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0048585 Not Cancer Driver No 46 0.16 81 13 0.16 0
HOMER2 HOMER2 Q9NSB8 Homer protein homolog 2 chr15 GO:0048585 Not Cancer Driver No 53 0.15 233 32 0.137 1
HOMER3_ENST00000542541 HOMER3 Q9NSC5 Homer protein homolog 3 chr19 GO:0048585 Not Cancer Driver No 31 0.086 251 15 0.06 0
HRG HRG P04196 Histidine-rich glycoprotein chr3 GO:0048585 Not Cancer Driver No 121 0.23 277 75 0.271 2
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0048585 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0048585 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPA1B HSPA1B P0DMV9 Heat shock 70 kDa protein 1B chr6 GO:0048585 Not Cancer Driver No 15 0.023 200 5 0.025 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 GO:0048585 Not Cancer Driver No 73 0.112 282 35 0.124 0
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 GO:0048585 Not Cancer Driver No 10 0.049 118 8 0.068 20
HTRA1 HTRA1 Q92743 Serine protease HTRA1 chr10 GO:0048585 Not Cancer Driver No 77 0.16 40 9 0.225 11
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 GO:0048585 Compendium Yes 44 0.096 127 9 0.071 2
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:0048585 Not Cancer Driver No 52 0.11 8 1 0.125 0
HYOU1 HYOU1 Q9Y4L1 Hypoxia up-regulated protein 1 chr11 GO:0048585 Not Cancer Driver No 132 0.132 373 47 0.126 0
ICAM1 ICAM1 P05362 Intercellular adhesion molecule 1 chr19 GO:0048585 Not Cancer Driver No 61 0.115 251 28 0.112 0
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 GO:0048585 Not Cancer Driver No 155 0.197 419 90 0.215 0
IFI35_ENST00000415816 IFI35 P80217 Interferon-induced 35 kDa protein chr17 GO:0048585 Not Cancer Driver No 33 0.115 63 10 0.159 0
IFI6_ENST00000361157 IFI6 P09912 Interferon alpha-inducible protein 6 chr1 GO:0048585 Not Cancer Driver No 12 0.092 7 0 0.0 0
IFNA2 IFNA2 P01563 Interferon alpha-2 chr9 GO:0048585 Not Cancer Driver No 38 0.202 2 0 0.0 0
IFNB1 IFNB1 P01574 Interferon beta chr9 GO:0048585 Not Cancer Driver No 46 0.246 0 0 0.0 0
IFNL1 IFNL1 Q8IU54 Interferon lambda-1 chr19 GO:0048585 Not Cancer Driver No 24 0.12 49 8 0.163 0
IFT122_ENST00000348417 IFT122 Q9HBG6 Intraflagellar transport protein 122 homolog chr3 GO:0048585 Not Cancer Driver No 157 0.127 54 5 0.093 5
IFT172 IFT172 Q9UG01 Intraflagellar transport protein 172 homolog chr2 GO:0048585 Not Cancer Driver No 219 0.125 96 10 0.104 8
IFT80 IFT80 Q9P2H3 Intraflagellar transport protein 80 homolog chr3 GO:0048585 Not Cancer Driver No 117 0.151 21 2 0.095 2
IGBP1_ENST00000356413 IGBP1 P78318 Immunoglobulin-binding protein 1 chrX GO:0048585 Not Cancer Driver No 51 0.15 193 28 0.145 0
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0048585 Not Cancer Driver No 45 0.231 87 23 0.264 0
IGFBP5 IGFBP5 P24593 Insulin-like growth factor-binding protein 5 chr2 GO:0048585 Not Cancer Driver No 27 0.099 112 17 0.152 0
IGSF1_ENST00000361420 IGSF1 Q8N6C5 Immunoglobulin superfamily member 1 chrX GO:0048585 Not Cancer Driver No 336 0.251 186 48 0.258 3
IL10 IL10 P22301 Interleukin-10 chr1 GO:0048585 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0048585 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL13RA2_ENST00000243213 IL13RA2 Q14627 Interleukin-13 receptor subunit alpha-2 chrX GO:0048585 Not Cancer Driver No 69 0.182 0 0 0.0 0
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0048585 Not Cancer Driver No 30 0.111 35 6 0.171 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0048585 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL1R2_ENST00000393414 IL1R2 P27930 Interleukin-1 receptor type 2 chr2 GO:0048585 Not Cancer Driver No 75 0.188 32 10 0.312 0
IL1RL1 IL1RL1 Q01638 Interleukin-1 receptor-like 1 chr2 GO:0048585 Not Cancer Driver No 119 0.214 24 8 0.333 0
IL1RN_ENST00000409930 IL1RN P18510 Interleukin-1 receptor antagonist protein chr2 GO:0048585 Not Cancer Driver No 34 0.192 17 7 0.412 0
IL2 IL2 P60568 Interleukin-2 chr4 GO:0048585 Census Yes 24 0.157 6 1 0.167 0
IL20RB IL20RB Q6UXL0 Interleukin-20 receptor subunit beta chr3 GO:0048585 Not Cancer Driver No 40 0.129 0 0 0.0 0
IL27RA IL27RA Q6UWB1 Interleukin-27 receptor subunit alpha chr19 GO:0048585 Not Cancer Driver No 91 0.143 167 23 0.138 0
IL36RN_ENST00000346807 IL36RN Q9UBH0 Interleukin-36 receptor antagonist protein chr2 GO:0048585 Not Cancer Driver No 34 0.219 7 4 0.571 4
IL4 IL4 P05112 Interleukin-4 chr5 GO:0048585 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL4I1_ENST00000391826 IL4I1 Q96RQ9 L-amino-acid oxidase chr19 GO:0048585 Not Cancer Driver No 65 0.115 136 14 0.103 0
IL4R_ENST00000543915 IL4R P24394 Interleukin-4 receptor subunit alpha chr16 GO:0048585 Not Cancer Driver No 133 0.161 420 64 0.152 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0048585 Not Cancer Driver No 35 0.165 58 7 0.121 0
IL7 IL7 P13232 Interleukin-7 chr8 GO:0048585 Not Cancer Driver No 29 0.164 19 4 0.211 0
IL7R IL7R P16871 Interleukin-7 receptor subunit alpha chr5 GO:0048585 Census, Compendium Yes 177 0.386 88 48 0.545 1
IL9 IL9 P15248 Interleukin-9 chr5 GO:0048585 Not Cancer Driver No 12 0.083 4 0 0.0 0
ING2 ING2 Q9H160 Inhibitor of growth protein 2 chr4 GO:0048585 Not Cancer Driver No 33 0.118 169 26 0.154 0
INPP5D INPP5D Q92835 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 chr2 GO:0048585 Not Cancer Driver No 176 0.148 578 90 0.156 0
INPP5E INPP5E Q9NRR6 Phosphatidylinositol polyphosphate 5-phosphatase type IV chr9 GO:0048585 Not Cancer Driver No 43 0.067 272 16 0.059 15
INPP5F INPP5F Q9Y2H2 Phosphatidylinositide phosphatase SAC2 chr10 GO:0048585 Not Cancer Driver No 138 0.122 394 45 0.114 0
INPP5K INPP5K Q9BT40 Inositol polyphosphate 5-phosphatase K chr17 GO:0048585 Not Cancer Driver No 42 0.094 34 2 0.059 7
INS INS P01308 Insulin chr11 GO:0048585 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSIG1 INSIG1 O15503 Insulin-induced gene 1 protein chr7 GO:0048585 Not Cancer Driver No 37 0.134 43 1 0.023 0
INSIG2 INSIG2 Q9Y5U4 Insulin-induced gene 2 protein chr2 GO:0048585 Not Cancer Driver No 47 0.209 11 3 0.273 0
IRAK3 IRAK3 Q9Y616 Interleukin-1 receptor-associated kinase 3 chr12 GO:0048585 Not Cancer Driver No 103 0.173 79 14 0.177 0
IRF4 IRF4 Q15306 Interferon regulatory factor 4 chr6 GO:0048585 Census, Compendium Yes 99 0.22 155 45 0.29 0
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 GO:0048585 Not Cancer Driver No 161 0.13 1072 133 0.124 2
ISG15 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 GO:0048585 Not Cancer Driver No 12 0.073 24 2 0.083 0
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0048585 Not Cancer Driver No 85 0.244 180 41 0.228 0
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 GO:0048585 Not Cancer Driver No 95 0.105 335 42 0.125 0
ITFG2 ITFG2 Q969R8 KICSTOR complex protein ITFG2 chr12 GO:0048585 Not Cancer Driver No 59 0.132 61 9 0.148 0
ITGA1 ITGA1 P56199 Integrin alpha-1 chr5 GO:0048585 Not Cancer Driver No 156 0.132 107 13 0.121 0
ITGA3 ITGA3 P26006 Integrin alpha-3 chr17 GO:0048585 Not Cancer Driver No 106 0.101 129 18 0.14 3
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0048585 Not Cancer Driver No 26 0.13 58 11 0.19 0
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 GO:0048585 Not Cancer Driver No 103 0.129 84 10 0.119 0
ITPR1_ENST00000354582 ITPR1 Q14643 Inositol 1,4,5-trisphosphate receptor type 1 chr3 GO:0048585 Not Cancer Driver No 390 0.141 581 76 0.131 6
ITPRIP_ENST00000358187 ITPRIP Q8IWB1 Inositol 1,4,5-trisphosphate receptor-interacting protein chr10 GO:0048585 Not Cancer Driver No 62 0.113 66 10 0.152 0
JAGN1 JAGN1 Q8N5M9 Protein jagunal homolog 1 chr3 GO:0048585 Not Cancer Driver No 21 0.115 12 2 0.167 5
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 GO:0048585 Census, Compendium Yes 167 0.149 63 10 0.159 7
KANK1_ENST00000382303 KANK1 Q14678 KN motif and ankyrin repeat domain-containing protein 1 chr9 GO:0048585 Not Cancer Driver No 183 0.135 804 100 0.124 0
KANK2_ENST00000586659 KANK2 Q63ZY3 KN motif and ankyrin repeat domain-containing protein 2 chr19 GO:0048585 Not Cancer Driver No 107 0.126 531 71 0.134 3
KCTD10 KCTD10 Q9H3F6 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 chr12 GO:0048585 Not Cancer Driver No 68 0.217 73 19 0.26 0
KCTD13 KCTD13 Q8WZ19 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 chr16 GO:0048585 Not Cancer Driver No 33 0.1 95 10 0.105 0
KCTD21 KCTD21 Q4G0X4 BTB/POZ domain-containing protein KCTD21 chr11 GO:0048585 Not Cancer Driver No 40 0.154 11 0 0.0 0
KCTD6_ENST00000490264 KCTD6 Q8NC69 BTB/POZ domain-containing protein KCTD6 chr3 GO:0048585 Not Cancer Driver No 27 0.114 12 1 0.083 0
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 GO:0048585 Not Cancer Driver No 67 0.079 291 28 0.096 3
KIAA0319_ENST00000543707 KIAA0319 Q5VV43 Dyslexia-associated protein KIAA0319 chr6 GO:0048585 Not Cancer Driver No 204 0.19 492 85 0.173 0
KIF7 KIF7 Q2M1P5 Kinesin-like protein KIF7 chr15 GO:0048585 Not Cancer Driver No 150 0.112 844 104 0.123 5
KLF7 KLF7 O75840 Krueppel-like factor 7 chr2 GO:0048585 Not Cancer Driver No 46 0.152 72 7 0.097 0
KLHL31 KLHL31 Q9H511 Kelch-like protein 31 chr6 GO:0048585 Not Cancer Driver No 69 0.109 32 1 0.031 0
KLK14_ENST00000156499 KLK14 Q9P0G3 Kallikrein-14 chr19 GO:0048585 Not Cancer Driver No 41 0.154 29 6 0.207 0
KLK8_ENST00000600767 KLK8 O60259 Kallikrein-8 chr19 GO:0048585 Not Cancer Driver No 65 0.25 76 15 0.197 0
KLKB1 KLKB1 P03952 Plasma kallikrein chr4 GO:0048585 Not Cancer Driver No 117 0.183 24 1 0.042 3
KLRC1 KLRC1 P26715 NKG2-A/NKG2-B type II integral membrane protein chr12 GO:0048585 Not Cancer Driver No 49 0.21 49 10 0.204 0
KLRD1 KLRD1 Q13241 Natural killer cells antigen CD94 chr12 GO:0048585 Not Cancer Driver No 37 0.207 0 0 0.0 0
KLRK1 KLRK1 P26718 NKG2-D type II integral membrane protein chr12 GO:0048585 Not Cancer Driver No 38 0.176 0 0 0.0 0
KPTN KPTN Q9Y664 KICSTOR complex protein kaptin chr19 GO:0048585 Not Cancer Driver No 44 0.101 21 2 0.095 0
KREMEN1_ENST00000407188 KREMEN1 Q96MU8 Kremen protein 1 chr22 GO:0048585 Not Cancer Driver No 68 0.144 73 7 0.096 1
KRT1 KRT1 P04264 Keratin, type II cytoskeletal 1 chr12 GO:0048585 Not Cancer Driver No 133 0.207 426 98 0.23 20
LACRT LACRT Q9GZZ8 Extracellular glycoprotein lacritin chr12 GO:0048585 Not Cancer Driver No 38 0.275 90 27 0.3 0
LAPTM5 LAPTM5 Q13571 Lysosomal-associated transmembrane protein 5 chr1 GO:0048585 Not Cancer Driver No 46 0.176 16 6 0.375 0
LBH LBH Q53QV2 Protein LBH chr2 GO:0048585 Not Cancer Driver No 15 0.143 72 10 0.139 0
LDLR LDLR P01130 Low-density lipoprotein receptor chr19 GO:0048585 Not Cancer Driver No 119 0.138 63 3 0.048 104
LDLRAD4 LDLRAD4 O15165 Low-density lipoprotein receptor class A domain-containing protein 4 chr18 GO:0048585 Not Cancer Driver No 66 0.216 191 39 0.204 0
LEMD2_ENST00000614475 LEMD2 Q8NC56 LEM domain-containing protein 2 chr6 GO:0048585 Not Cancer Driver No 44 0.087 211 4 0.019 2
LEMD3 LEMD3 Q9Y2U8 Inner nuclear membrane protein Man1 chr12 GO:0048585 Not Cancer Driver No 78 0.086 509 33 0.065 0
LEP LEP P41159 Leptin chr7 GO:0048585 Not Cancer Driver No 29 0.174 0 0 0.0 2
LEPROTL1_ENST00000321250 LEPROTL1 O95214 Leptin receptor overlapping transcript-like 1 chr8 GO:0048585 Census Yes 8 0.061 0 0 0.0 0
LEPROT_ENST00000371065 LEPROT O15243 Leptin receptor gene-related protein chr1 GO:0048585 Not Cancer Driver No 16 0.122 0 0 0.0 0
LFNG LFNG Q8NES3 Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe chr7 GO:0048585 Not Cancer Driver No 37 0.098 65 1 0.015 1
LGALS3 LGALS3 P17931 Galectin-3 chr14 GO:0048585 Not Cancer Driver No 15 0.06 133 6 0.045 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0048585 Not Cancer Driver No 54 0.152 65 16 0.246 0
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 GO:0048585 Not Cancer Driver No 57 0.132 112 19 0.17 0
LGR4 LGR4 Q9BXB1 Leucine-rich repeat-containing G-protein coupled receptor 4 chr11 GO:0048585 Not Cancer Driver No 108 0.114 16 3 0.188 0
LIF LIF P15018 Leukemia inhibitory factor chr22 GO:0048585 Not Cancer Driver No 25 0.124 0 0 0.0 0
LILRA2 LILRA2 Q8N149 Leukocyte immunoglobulin-like receptor subfamily A member 2 chr19 GO:0048585 Not Cancer Driver No 163 0.337 137 44 0.321 0
LILRA4 LILRA4 P59901 Leukocyte immunoglobulin-like receptor subfamily A member 4 chr19 GO:0048585 Not Cancer Driver No 124 0.248 109 26 0.239 0
LILRB1_ENST00000396331 LILRB1 Q8NHL6 Leukocyte immunoglobulin-like receptor subfamily B member 1 chr19 GO:0048585 Not Cancer Driver No 203 0.312 291 97 0.333 0
LILRB4 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 GO:0048585 Not Cancer Driver No 162 0.362 277 115 0.415 0
LIMD1 LIMD1 Q9UGP4 LIM domain-containing protein 1 chr3 GO:0048585 Not Cancer Driver No 58 0.086 428 36 0.084 0
LITAF_ENST00000570904 LITAF Q99732 Lipopolysaccharide-induced tumor necrosis factor-alpha factor chr16 GO:0048585 Not Cancer Driver No 21 0.13 67 6 0.09 5
LMNA LMNA P02545 Prelamin-A/C chr1 GO:0048585 Census Yes 68 0.102 544 49 0.09 131
LMO3_ENST00000534946 LMO3 Q8TAP4 LIM domain only protein 3 chr12 GO:0048585 Not Cancer Driver No 30 0.207 1 0 0.0 0
LOXL3 LOXL3 P58215 Lysyl oxidase homolog 3 chr2 GO:0048585 Not Cancer Driver No 91 0.121 86 17 0.198 0
LPCAT3 LPCAT3 Q6P1A2 Lysophospholipid acyltransferase 5 chr12 GO:0048585 Not Cancer Driver No 54 0.111 1 0 0.0 0
LPL LPL P06858 Lipoprotein lipase chr8 GO:0048585 Not Cancer Driver No 94 0.198 23 3 0.13 70
LPXN_ENST00000395074 LPXN O60711 Leupaxin chr11 GO:0048585 Not Cancer Driver No 43 0.111 134 16 0.119 0
LRIG2 LRIG2 O94898 Leucine-rich repeats and immunoglobulin-like domains protein 2 chr1 GO:0048585 Not Cancer Driver No 131 0.123 231 30 0.13 0
LRP1 LRP1 Q07954 Prolow-density lipoprotein receptor-related protein 1 chr12 GO:0048585 Not Cancer Driver No 664 0.146 317 52 0.164 1
LRPAP1 LRPAP1 P30533 Alpha-2-macroglobulin receptor-associated protein chr4 GO:0048585 Not Cancer Driver No 41 0.115 188 20 0.106 0
LRRC14 LRRC14 Q15048 Leucine-rich repeat-containing protein 14 chr8 GO:0048585 Not Cancer Driver No 63 0.128 25 2 0.08 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0048585 Not Cancer Driver No 519 0.205 90 17 0.189 23
LTBP1 LTBP1 Q14766 Latent-transforming growth factor beta-binding protein 1 chr2 GO:0048585 Not Cancer Driver No 300 0.174 518 78 0.151 0
LTF LTF P02788 Lactotransferrin chr3 GO:0048585 Not Cancer Driver No 131 0.185 21 4 0.19 0
LY6G6E LY6G6E A0A0B4J1T7 Lymphocyte antigen 6 family member G6E chr6 GO:0048585 Not Cancer Driver No 4 0.032 0 0 0.0 0
LYAR_ENST00000452476 LYAR Q9NX58 Cell growth-regulating nucleolar protein chr4 GO:0048585 Not Cancer Driver No 50 0.132 249 31 0.124 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0048585 Census Yes 95 0.186 84 12 0.143 0
MAD2L1BP_ENST00000372171 MAD2L1BP Q15013 MAD2L1-binding protein chr6 GO:0048585 Not Cancer Driver No 26 0.095 55 7 0.127 0
MAGEA3 MAGEA3 P43357 Melanoma-associated antigen 3 chrX GO:0048585 Not Cancer Driver No 79 0.252 103 18 0.175 0
MAGI2 MAGI2 Q86UL8 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 chr7 GO:0048585 Not Cancer Driver No 305 0.21 1086 201 0.185 0
MAP2K3 MAP2K3 P46734 Dual specificity mitogen-activated protein kinase kinase 3 chr17 GO:0048585 Not Cancer Driver No 104 0.3 75 27 0.36 0
MAP2K5 MAP2K5 Q13163 Dual specificity mitogen-activated protein kinase kinase 5 chr15 GO:0048585 Not Cancer Driver No 40 0.089 85 10 0.118 0
MAP3K3_ENST00000361733 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 GO:0048585 Not Cancer Driver No 74 0.118 355 44 0.124 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0048585 Not Cancer Driver No 39 0.108 25 1 0.04 0
MAPK7 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 GO:0048585 Not Cancer Driver No 92 0.113 490 50 0.102 0
MAPK8IP1 MAPK8IP1 Q9UQF2 C-Jun-amino-terminal kinase-interacting protein 1 chr11 GO:0048585 Not Cancer Driver No 79 0.111 444 40 0.09 1
MAPKBP1 MAPKBP1 O60336 Mitogen-activated protein kinase-binding protein 1 chr15 GO:0048585 Not Cancer Driver No 166 0.11 786 67 0.085 0
MARCH7 MARCHF7 Q9H992 E3 ubiquitin-protein ligase MARCHF7 chr2 GO:0048585 Not Cancer Driver No 85 0.121 550 68 0.124 0
MARK3 MARK3 P27448 MAP/microtubule affinity-regulating kinase 3 chr14 GO:0048585 Not Cancer Driver No 92 0.122 376 49 0.13 1
MARVELD3_ENST00000268485 MARVELD3 Q96A59 MARVEL domain-containing protein 3 chr16 GO:0048585 Not Cancer Driver No 40 0.1 179 10 0.056 0
MCL1 MCL1 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 chr1 GO:0048585 Not Cancer Driver No 30 0.086 203 21 0.103 0
MCTP1 MCTP1 Q6DN14 Multiple C2 and transmembrane domain-containing protein 1 chr5 GO:0048585 Not Cancer Driver No 162 0.162 323 29 0.09 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0048585 Not Cancer Driver No 15 0.105 20 2 0.1 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 GO:0048585 Census, Compendium Yes 56 0.114 297 37 0.125 0
MECOM_ENST00000494292 MECOM Q03112 Histone-lysine N-methyltransferase MECOM chr3 GO:0048585 Census, Compendium Yes 287 0.233 749 159 0.212 3
MEGF8 MEGF8 Q7Z7M0 Multiple epidermal growth factor-like domains protein 8 chr19 GO:0048585 Not Cancer Driver No 363 0.128 476 59 0.124 3
MEN1 MEN1 O00255 Menin chr11 GO:0048585 Census, Compendium Yes 73 0.119 228 15 0.066 90
MESP1 MESP1 Q9BRJ9 Mesoderm posterior protein 1 chr15 GO:0048585 Not Cancer Driver No 8 0.03 247 7 0.028 0
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 GO:0048585 Not Cancer Driver No 74 0.128 274 29 0.106 0
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 GO:0048585 Census, Compendium Yes 226 0.163 62 15 0.242 19
MFHAS1 MFHAS1 Q9Y4C4 Malignant fibrous histiocytoma-amplified sequence 1 chr8 GO:0048585 Not Cancer Driver No 95 0.09 98 9 0.092 0
MGRN1_ENST00000399577 MGRN1 O60291 E3 ubiquitin-protein ligase MGRN1 chr16 GO:0048585 Not Cancer Driver No 76 0.138 228 37 0.162 0
MICB MICB Q29980 MHC class I polypeptide-related sequence B chr6 GO:0048585 Not Cancer Driver No 56 0.146 175 22 0.126 0
MIF MIF P14174 Macrophage migration inhibitory factor chr22 GO:0048585 Not Cancer Driver No 4 0.035 0 0 0.0 0
MKKS MKKS Q9NPJ1 McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin chr20 GO:0048585 Not Cancer Driver No 56 0.098 6 1 0.167 22
MKRN2 MKRN2 Q9H000 E3 ubiquitin-protein ligase makorin-2 chr3 GO:0048585 Not Cancer Driver No 45 0.108 145 16 0.11 0
MLIP_ENST00000274897 MLIP Q5VWP3 Muscular LMNA-interacting protein chr6 GO:0048585 Not Cancer Driver No 99 0.216 406 87 0.214 0
MMP12 MMP12 P39900 Macrophage metalloelastase chr11 GO:0048585 Not Cancer Driver No 100 0.213 29 5 0.172 0
MMP9 MMP9 P14780 Matrix metalloproteinase-9 chr20 GO:0048585 Not Cancer Driver No 129 0.182 124 26 0.21 0
MMRN1 MMRN1 Q13201 Multimerin-1 chr4 GO:0048585 Not Cancer Driver No 241 0.196 373 75 0.201 0
MMRN2 MMRN2 Q9H8L6 Multimerin-2 chr10 GO:0048585 Not Cancer Driver No 98 0.103 420 49 0.117 0
MOSMO MOSMO Q8NHV5 Modulator of smoothened protein chr16 GO:0048585 Not Cancer Driver No 3 0.018 0 0 0.0 0
MPV17L MPV17L Q2QL34 Mpv17-like protein chr16 GO:0048585 Not Cancer Driver No 16 0.082 3 0 0.0 0
MRAP MRAP Q8TCY5 Melanocortin-2 receptor accessory protein chr21 GO:0048585 Not Cancer Driver No 29 0.169 63 7 0.111 0
MRAP2 MRAP2 Q96G30 Melanocortin-2 receptor accessory protein 2 chr6 GO:0048585 Not Cancer Driver No 55 0.268 75 17 0.227 0
MSTN MSTN O14793 Growth/differentiation factor 8 chr2 GO:0048585 Not Cancer Driver No 68 0.181 64 11 0.172 0
MTM1 MTM1 Q13496 Myotubularin chrX GO:0048585 Not Cancer Driver No 112 0.186 79 9 0.114 57
MTMR2 MTMR2 Q13614 Myotubularin-related protein 2 chr11 GO:0048585 Not Cancer Driver No 70 0.109 140 16 0.114 1
MTNR1B MTNR1B P49286 Melatonin receptor type 1B chr11 GO:0048585 Not Cancer Driver No 104 0.287 8 1 0.125 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0048585 Census, Compendium Yes 379 0.149 296 37 0.125 18
MUC1_ENST00000611571 MUC1 P15941 Mucin-1 chr1 GO:0048585 Census Yes 40 0.032 1050 19 0.018 0
MUL1 MUL1 Q969V5 Mitochondrial ubiquitin ligase activator of NFKB 1 chr1 GO:0048585 Not Cancer Driver No 48 0.136 16 2 0.125 0
MVP MVP Q14764 Major vault protein chr16 GO:0048585 Not Cancer Driver No 141 0.158 285 31 0.109 0
MYADM MYADM Q96S97 Myeloid-associated differentiation marker chr19 GO:0048585 Not Cancer Driver No 73 0.227 0 0 0.0 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0048585 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYOC MYOC Q99972 Myocilin chr1 GO:0048585 Not Cancer Driver No 92 0.183 196 43 0.219 58
MYOCD_ENST00000343344 MYOCD Q8IZQ8 Myocardin chr17 GO:0048585 Not Cancer Driver No 284 0.303 853 263 0.308 0
MYOZ1 MYOZ1 Q9NP98 Myozenin-1 chr10 GO:0048585 Not Cancer Driver No 49 0.164 223 39 0.175 0
MYOZ2 MYOZ2 Q9NPC6 Myozenin-2 chr4 GO:0048585 Not Cancer Driver No 50 0.189 197 38 0.193 2
NAIP_ENST00000194097 NAIP Q13075 Baculoviral IAP repeat-containing protein 1 chr5 GO:0048585 Not Cancer Driver No 39 0.028 67 4 0.06 0
NBL1_ENST00000602662 NBL1 P41271 Neuroblastoma suppressor of tumorigenicity 1 chr1 GO:0048585 Not Cancer Driver No 18 0.099 64 4 0.062 0
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 GO:0048585 Not Cancer Driver No 48 0.127 111 17 0.153 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 GO:0048585 Not Cancer Driver No 89 0.234 88 19 0.216 0
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:0048585 Not Cancer Driver No 247 0.219 51 10 0.196 4
NCOA5 NCOA5 Q9HCD5 Nuclear receptor coactivator 5 chr20 GO:0048585 Not Cancer Driver No 84 0.145 478 70 0.146 0
NCOA7_ENST00000368357 NCOA7 Q8NI08 Nuclear receptor coactivator 7 chr6 GO:0048585 Not Cancer Driver No 110 0.117 538 63 0.117 0
NCOR1 NCOR1 O75376 Nuclear receptor corepressor 1 chr17 GO:0048585 Census, Compendium Yes 352 0.144 2347 340 0.145 0
NCOR2 NCOR2 Q9Y618 Nuclear receptor corepressor 2 chr12 GO:0048585 Census, Compendium Yes 373 0.148 2355 356 0.151 0
NDFIP1 NDFIP1 Q9BT67 NEDD4 family-interacting protein 1 chr5 GO:0048585 Not Cancer Driver No 22 0.1 44 4 0.091 0
NDRG2 NDRG2 Q9UN36 Protein NDRG2 chr14 GO:0048585 Not Cancer Driver No 45 0.121 111 8 0.072 0
NDRG4_ENST00000570248 NDRG4 Q9ULP0 Protein NDRG4 chr16 GO:0048585 Not Cancer Driver No 44 0.125 90 11 0.122 0
NDUFAF2 NDUFAF2 Q8N183 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 chr5 GO:0048585 Not Cancer Driver No 21 0.124 116 13 0.112 0
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 GO:0048585 Not Cancer Driver No 150 0.114 711 79 0.111 0
NENF NENF Q9UMX5 Neudesin chr1 GO:0048585 Not Cancer Driver No 15 0.087 98 7 0.071 0
NEUROD1 NEUROD1 Q13562 Neurogenic differentiation factor 1 chr2 GO:0048585 Not Cancer Driver No 84 0.236 202 52 0.257 2
NF1 NF1 P21359 Neurofibromin chr17 GO:0048585 Census, Compendium Yes 375 0.132 406 47 0.116 85
NF2 NF2 P35240 Merlin chr22 GO:0048585 Census, Compendium Yes 69 0.116 252 26 0.103 16
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0048585 Census, Compendium Yes 228 0.377 402 62 0.154 4
NFKBIL1 NFKBIL1 Q9UBC1 NF-kappa-B inhibitor-like protein 1 chr6 GO:0048585 Not Cancer Driver No 37 0.097 316 33 0.104 0
NGFR NGFR P08138 Tumor necrosis factor receptor superfamily member 16 chr17 GO:0048585 Not Cancer Driver No 57 0.133 172 25 0.145 0
NKX3-1 NKX3-1 Q99801 Homeobox protein Nkx-3.1 chr8 GO:0048585 Not Cancer Driver No 35 0.15 171 16 0.094 0
NLE1 NLE1 Q9NVX2 Notchless protein homolog 1 chr17 GO:0048585 Not Cancer Driver No 60 0.124 21 3 0.143 0
NLGN4X_ENST00000381093 NLGN4X Q8N0W4 Neuroligin-4, X-linked chrX GO:0048585 Not Cancer Driver No 279 0.342 211 81 0.384 0
NLRC3 NLRC3 Q7RTR2 NLR family CARD domain-containing protein 3 chr16 GO:0048585 Not Cancer Driver No 176 0.165 147 33 0.224 0
NLRC5_ENST00000436936 NLRC5 Q86WI3 Protein NLRC5 chr16 GO:0048585 Not Cancer Driver No 262 0.14 114 19 0.167 0
NLRP12_ENST00000324134 NLRP12 P59046 NACHT, LRR and PYD domains-containing protein 12 chr19 GO:0048585 Not Cancer Driver No 310 0.292 116 43 0.371 0
NLRP3_ENST00000391828 NLRP3 Q96P20 NACHT, LRR and PYD domains-containing protein 3 chr1 GO:0048585 Not Cancer Driver No 339 0.327 64 33 0.516 37
NLRP6 NLRP6 P59044 NACHT, LRR and PYD domains-containing protein 6 chr11 GO:0048585 Not Cancer Driver No 106 0.119 203 28 0.138 0
NLRX1_ENST00000409265 NLRX1 Q86UT6 NLR family member X1 chr11 GO:0048585 Not Cancer Driver No 158 0.162 94 13 0.138 0
NME5 NME5 P56597 Nucleoside diphosphate kinase homolog 5 chr5 GO:0048585 Not Cancer Driver No 17 0.08 6 0 0.0 0
NMI NMI Q13287 N-myc-interactor chr2 GO:0048585 Not Cancer Driver No 34 0.111 104 12 0.115 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0048585 Not Cancer Driver No 169 0.163 40 4 0.1 15
NODAL NODAL Q96S42 Nodal homolog chr10 GO:0048585 Not Cancer Driver No 40 0.115 34 8 0.235 4
NOG NOG Q13253 Noggin chr17 GO:0048585 Not Cancer Driver No 22 0.095 86 9 0.105 20
NOL3_ENST00000268605 NOL3 O60936 Nucleolar protein 3 chr16 GO:0048585 Not Cancer Driver No 20 0.096 179 17 0.095 2
NOMO3 NOMO3 P69849 Nodal modulator 3 chr16 GO:0048585 Not Cancer Driver No 44 0.036 129 3 0.023 0
NONO NONO Q15233 Non-POU domain-containing octamer-binding protein chrX GO:0048585 Census, Compendium Yes 101 0.214 349 64 0.183 0
NOP53 NOP53 Q9NZM5 Ribosome biogenesis protein NOP53 chr19 GO:0048585 Not Cancer Driver No 59 0.123 391 41 0.105 0
NOS3 NOS3 P29474 Nitric oxide synthase, endothelial chr7 GO:0048585 Not Cancer Driver No 168 0.14 347 38 0.11 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0048585 Census, Compendium Yes 363 0.142 686 87 0.127 3
NPLOC4 NPLOC4 Q8TAT6 Nuclear protein localization protein 4 homolog chr17 GO:0048585 Not Cancer Driver No 78 0.128 47 8 0.17 0
NPPA NPPA P01160 Natriuretic peptides A chr1 GO:0048585 Not Cancer Driver No 32 0.212 71 14 0.197 1
NPRL2 NPRL2 Q8WTW4 GATOR complex protein NPRL2 chr3 GO:0048585 Compendium Yes 37 0.097 10 3 0.3 1
NPRL3_ENST00000611875 NPRL3 Q12980 GATOR complex protein NPRL3 chr16 GO:0048585 Not Cancer Driver No 45 0.079 158 22 0.139 0
NPY5R_ENST00000506953 NPY5R Q15761 Neuropeptide Y receptor type 5 chr4 GO:0048585 Not Cancer Driver No 144 0.324 44 16 0.364 0
NPY_ENST00000405982 NPY P01303 Pro-neuropeptide Y chr7 GO:0048585 Not Cancer Driver No 29 0.299 43 19 0.442 0
NR0B1 NR0B1 P51843 Nuclear receptor subfamily 0 group B member 1 chrX GO:0048585 Not Cancer Driver No 106 0.226 97 18 0.186 18
NR1D1 NR1D1 P20393 Nuclear receptor subfamily 1 group D member 1 chr17 GO:0048585 Not Cancer Driver No 81 0.132 348 49 0.141 0
NR1H2_ENST00000593926 NR1H2 P55055 Oxysterols receptor LXR-beta chr19 GO:0048585 Not Cancer Driver No 56 0.122 179 30 0.168 0
NR1H3_ENST00000467728 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 GO:0048585 Not Cancer Driver No 56 0.125 146 13 0.089 0
NR1H4 NR1H4 Q96RI1 Bile acid receptor chr12 GO:0048585 Not Cancer Driver No 111 0.228 78 18 0.231 0
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:0048585 Census Yes 83 0.133 298 37 0.124 0
NRARP NRARP Q7Z6K4 Notch-regulated ankyrin repeat-containing protein chr9 GO:0048585 Not Cancer Driver No 9 0.079 11 1 0.091 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0048585 Compendium Yes 146 0.158 211 31 0.147 0
NRROS NRROS Q86YC3 Transforming growth factor beta activator LRRC33 chr3 GO:0048585 Not Cancer Driver No 109 0.158 8 1 0.125 0
NUCB2_ENST00000622082 NUCB2 P80303 Nucleobindin-2 chr11 GO:0048585 Not Cancer Driver No 49 0.117 265 40 0.151 0
NUDT16L1 NUDT16L1 Q9BRJ7 Tudor-interacting repair regulator protein chr16 GO:0048585 Not Cancer Driver No 16 0.076 6 0 0.0 0
NUP62 NUP62 P37198 Nuclear pore glycoprotein p62 chr19 GO:0048585 Not Cancer Driver No 76 0.146 377 56 0.149 1
OAS1_ENST00000202917 OAS1 P00973 2'-5'-oligoadenylate synthase 1 chr12 GO:0048585 Not Cancer Driver No 67 0.168 71 12 0.169 0
OAS3 OAS3 Q9Y6K5 2'-5'-oligoadenylate synthase 3 chr12 GO:0048585 Not Cancer Driver No 139 0.128 147 17 0.116 0
OGG1_ENST00000344629 OGG1 O15527 N-glycosylase/DNA lyase chr3 GO:0048585 Not Cancer Driver No 37 0.107 71 12 0.169 0
OPA1_ENST00000392438 OPA1 O60313 Dynamin-like 120 kDa protein, mitochondrial chr3 GO:0048585 Not Cancer Driver No 114 0.119 131 17 0.13 60
OPRL1_ENST00000336866 OPRL1 P41146 Nociceptin receptor chr20 GO:0048585 Not Cancer Driver No 81 0.219 0 0 0.0 0
OPRM1_ENST00000330432 OPRM1 P35372 Mu-type opioid receptor chr6 GO:0048585 Not Cancer Driver No 107 0.268 58 27 0.466 0
OTOP1 OTOP1 Q7RTM1 Proton channel OTOP1 chr4 GO:0048585 Not Cancer Driver No 104 0.17 89 11 0.124 0
OTUD3 OTUD3 Q5T2D3 OTU domain-containing protein 3 chr1 GO:0048585 Not Cancer Driver No 43 0.108 280 25 0.089 0
OTUD4_ENST00000447906 OTUD4 Q01804 OTU domain-containing protein 4 chr4 GO:0048585 Not Cancer Driver No 148 0.133 788 120 0.152 0
OXR1 OXR1 Q8N573 Oxidation resistance protein 1 chr8 GO:0048585 Not Cancer Driver No 126 0.144 544 76 0.14 0
PADI2 PADI2 Q9Y2J8 Protein-arginine deiminase type-2 chr1 GO:0048585 Not Cancer Driver No 121 0.182 60 18 0.3 0
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:0048585 Not Cancer Driver No 42 0.102 82 11 0.134 7
PALM PALM O75781 Paralemmin-1 chr19 GO:0048585 Not Cancer Driver No 50 0.129 381 50 0.131 0
PALM3 PALM3 A6NDB9 Paralemmin-3 chr19 GO:0048585 Not Cancer Driver No 26 0.039 635 23 0.036 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0048585 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARL PARL Q9H300 Presenilins-associated rhomboid-like protein, mitochondrial chr3 GO:0048585 Not Cancer Driver No 49 0.129 28 5 0.179 0
PARP14 PARP14 Q460N5 Protein mono-ADP-ribosyltransferase PARP14 chr3 GO:0048585 Not Cancer Driver No 221 0.123 301 57 0.189 0
PARP3_ENST00000431474 PARP3 Q9Y6F1 Protein mono-ADP-ribosyltransferase PARP3 chr3 GO:0048585 Not Cancer Driver No 70 0.131 269 38 0.141 0
PAWR PAWR Q96IZ0 PRKC apoptosis WT1 regulator protein chr12 GO:0048585 Not Cancer Driver No 35 0.103 327 33 0.101 0
PBK_ENST00000301905 PBK Q96KB5 Lymphokine-activated killer T-cell-originated protein kinase chr8 GO:0048585 Not Cancer Driver No 23 0.071 92 6 0.065 0
PBLD PBLD P30039 Phenazine biosynthesis-like domain-containing protein chr10 GO:0048585 Not Cancer Driver No 41 0.142 5 1 0.2 0
PCBP2_ENST00000439930 PCBP2 Q15366 Poly(rC)-binding protein 2 chr12 GO:0048585 Not Cancer Driver No 40 0.11 200 24 0.12 0
PDCD1 PDCD1 Q15116 Programmed cell death protein 1 chr2 GO:0048585 Not Cancer Driver No 56 0.194 141 37 0.262 0
PDCD4 PDCD4 Q53EL6 Programmed cell death protein 4 chr10 GO:0048585 Not Cancer Driver No 57 0.122 187 32 0.171 0
PDCD6 PDCD6 O75340 Programmed cell death protein 6 chr5 GO:0048585 Not Cancer Driver No 21 0.11 24 1 0.042 0
PDE10A_ENST00000366882 PDE10A Q9Y233 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A chr6 GO:0048585 Not Cancer Driver No 198 0.254 79 21 0.266 4
PDE2A PDE2A O00408 cGMP-dependent 3',5'-cyclic phosphodiesterase chr11 GO:0048585 Not Cancer Driver No 137 0.146 99 7 0.071 0
PDE4B PDE4B Q07343 cAMP-specific 3',5'-cyclic phosphodiesterase 4B chr1 GO:0048585 Not Cancer Driver No 119 0.162 363 42 0.116 0
PDE8A_ENST00000394553 PDE8A O60658 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A chr15 GO:0048585 Not Cancer Driver No 78 0.094 187 17 0.091 0
PDGFA PDGFA P04085 Platelet-derived growth factor subunit A chr7 GO:0048585 Not Cancer Driver No 31 0.147 75 10 0.133 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0048585 Census Yes 37 0.154 99 22 0.222 2
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 GO:0048585 Census, Compendium Yes 290 0.266 173 45 0.26 2
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0048585 Not Cancer Driver No 33 0.059 121 12 0.099 0
PDX1 PDX1 P52945 Pancreas/duodenum homeobox protein 1 chr13 GO:0048585 Not Cancer Driver No 32 0.113 238 23 0.097 0
PDZD3_ENST00000531114 PDZD3 Q86UT5 Na(+)/H(+) exchange regulatory cofactor NHE-RF4 chr11 GO:0048585 Not Cancer Driver No 58 0.102 199 19 0.095 0
PEA15_ENST00000360472 PEA15 Q15121 Astrocytic phosphoprotein PEA-15 chr1 GO:0048585 Not Cancer Driver No 12 0.092 35 5 0.143 0
PELI3 PELI3 Q8N2H9 E3 ubiquitin-protein ligase pellino homolog 3 chr11 GO:0048585 Not Cancer Driver No 48 0.102 216 25 0.116 0
PER1 PER1 O15534 Period circadian protein homolog 1 chr17 GO:0048585 Census Yes 160 0.124 948 116 0.122 0
PF4 PF4 P02776 Platelet factor 4 chr4 GO:0048585 Not Cancer Driver No 13 0.129 0 0 0.0 0
PGLYRP1 PGLYRP1 O75594 Peptidoglycan recognition protein 1 chr19 GO:0048585 Not Cancer Driver No 34 0.173 4 0 0.0 0
PGLYRP2 PGLYRP2 Q96PD5 N-acetylmuramoyl-L-alanine amidase chr19 GO:0048585 Not Cancer Driver No 111 0.193 160 28 0.175 0
PHACTR4_ENST00000373839 PHACTR4 Q8IZ21 Phosphatase and actin regulator 4 chr1 GO:0048585 Not Cancer Driver No 80 0.114 679 76 0.112 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 GO:0048585 Not Cancer Driver No 31 0.104 26 4 0.154 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:0048585 Not Cancer Driver No 37 0.136 4 1 0.25 0
PHLDA3 PHLDA3 Q9Y5J5 Pleckstrin homology-like domain family A member 3 chr1 GO:0048585 Not Cancer Driver No 20 0.157 0 0 0.0 0
PHLDB2 PHLDB2 Q86SQ0 Pleckstrin homology-like domain family B member 2 chr3 GO:0048585 Not Cancer Driver No 235 0.188 1030 190 0.184 0
PHLPP1 PHLPP1 O60346 PH domain leucine-rich repeat-containing protein phosphatase 1 chr18 GO:0048585 Not Cancer Driver No 134 0.078 744 29 0.039 0
PHPT1 PHPT1 Q9NRX4 14 kDa phosphohistidine phosphatase chr9 GO:0048585 Not Cancer Driver No 13 0.104 6 0 0.0 0
PIAS2 PIAS2 O75928 E3 SUMO-protein ligase PIAS2 chr18 GO:0048585 Not Cancer Driver No 78 0.126 209 28 0.134 0
PIAS4 PIAS4 Q8N2W9 E3 SUMO-protein ligase PIAS4 chr19 GO:0048585 Not Cancer Driver No 58 0.114 142 23 0.162 0
PIBF1 PIBF1 Q8WXW3 Progesterone-induced-blocking factor 1 chr13 GO:0048585 Not Cancer Driver No 83 0.11 419 45 0.107 2
PID1 PID1 Q7Z2X4 PTB-containing, cubilin and LRP1-interacting protein chr2 GO:0048585 Not Cancer Driver No 70 0.28 24 10 0.417 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 GO:0048585 Not Cancer Driver No 30 0.103 157 13 0.083 0
PIK3CB_ENST00000477593 PIK3CB P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 GO:0048585 Census, Compendium Yes 150 0.14 42 4 0.095 0
PIK3IP1 PIK3IP1 Q96FE7 Phosphoinositide-3-kinase-interacting protein 1 chr22 GO:0048585 Not Cancer Driver No 27 0.103 128 13 0.102 0
PIM3 PIM3 Q86V86 Serine/threonine-protein kinase pim-3 chr22 GO:0048585 Not Cancer Driver No 24 0.074 9 0 0.0 0
PIN1 PIN1 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 chr19 GO:0048585 Not Cancer Driver No 17 0.104 115 12 0.104 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0048585 Not Cancer Driver No 57 0.098 99 13 0.131 23
PIP4K2A PIP4K2A P48426 Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha chr10 GO:0048585 Not Cancer Driver No 56 0.138 123 15 0.122 0
PIP4K2C_ENST00000540759 PIP4K2C Q8TBX8 Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma chr12 GO:0048585 Not Cancer Driver No 62 0.147 111 23 0.207 0
PKHD1 PKHD1 P08F94 Fibrocystin chr6 GO:0048585 Not Cancer Driver No 778 0.191 413 81 0.196 93
PLAT PLAT P00750 Tissue-type plasminogen activator chr8 GO:0048585 Not Cancer Driver No 89 0.158 15 2 0.133 0
PLAU PLAU P00749 Urokinase-type plasminogen activator chr10 GO:0048585 Not Cancer Driver No 59 0.137 10 0 0.0 0
PLAUR PLAUR Q03405 Urokinase plasminogen activator surface receptor chr19 GO:0048585 Not Cancer Driver No 49 0.146 18 5 0.278 0
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 GO:0048585 Census, Compendium Yes 158 0.122 186 21 0.113 0
PLCL2 PLCL2 Q9UPR0 Inactive phospholipase C-like protein 2 chr3 GO:0048585 Not Cancer Driver No 185 0.164 274 31 0.113 0
PLEK PLEK P08567 Pleckstrin chr2 GO:0048585 Not Cancer Driver No 81 0.231 39 9 0.231 0
PLEKHA1 PLEKHA1 Q9HB21 Pleckstrin homology domain-containing family A member 1 chr10 GO:0048585 Not Cancer Driver No 61 0.151 191 32 0.168 0
PLG PLG P00747 Plasminogen chr6 GO:0048585 Not Cancer Driver No 242 0.299 230 64 0.278 9
PLGLB2 PLGLB2 Q02325 Plasminogen-like protein B chr2 GO:0048585 Not Cancer Driver No 2 0.021 0 0 0.0 0
PLIN5 PLIN5 Q00G26 Perilipin-5 chr19 GO:0048585 Not Cancer Driver No 49 0.106 192 21 0.109 0
PLK2 PLK2 Q9NYY3 Serine/threonine-protein kinase PLK2 chr5 GO:0048585 Not Cancer Driver No 92 0.134 178 21 0.118 0
PLXNA3 PLXNA3 P51805 Plexin-A3 chrX GO:0048585 Not Cancer Driver No 243 0.13 199 34 0.171 0
PMEPA1 PMEPA1 Q969W9 Protein TMEPAI chr20 GO:0048585 Not Cancer Driver No 45 0.157 196 34 0.173 0
PPARA_ENST00000402126 PPARA Q07869 Peroxisome proliferator-activated receptor alpha chr22 GO:0048585 Not Cancer Driver No 63 0.135 68 9 0.132 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0048585 Census Yes 72 0.143 44 4 0.091 3
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 GO:0048585 Not Cancer Driver No 11 0.067 24 3 0.125 0
PPIF PPIF P30405 Peptidyl-prolyl cis-trans isomerase F, mitochondrial chr10 GO:0048585 Not Cancer Driver No 19 0.092 43 4 0.093 0
PPM1A_ENST00000395076 PPM1A P35813 Protein phosphatase 1A chr14 GO:0048585 Not Cancer Driver No 60 0.157 134 24 0.179 0
PPM1B PPM1B O75688 Protein phosphatase 1B chr2 GO:0048585 Not Cancer Driver No 65 0.136 243 31 0.128 0
PPP1R10 PPP1R10 Q96QC0 Serine/threonine-protein phosphatase 1 regulatory subunit 10 chr6 GO:0048585 Not Cancer Driver No 114 0.121 798 100 0.125 0
PPP1R15A PPP1R15A O75807 Protein phosphatase 1 regulatory subunit 15A chr19 GO:0048585 Not Cancer Driver No 83 0.123 628 72 0.115 0
PPP1R15B PPP1R15B Q5SWA1 Protein phosphatase 1 regulatory subunit 15B chr1 GO:0048585 Not Cancer Driver No 72 0.101 415 45 0.108 1
PPP2CA PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 GO:0048585 Not Cancer Driver No 41 0.133 12 1 0.083 8
PPP2CB PPP2CB P62714 Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform chr8 GO:0048585 Not Cancer Driver No 37 0.12 12 0 0.0 0
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 GO:0048585 Census, Compendium Yes 179 0.304 0 0 0.0 4
PPP3CB_ENST00000360663 PPP3CB P16298 Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform chr10 GO:0048585 Not Cancer Driver No 67 0.128 139 18 0.129 0
PRAME_ENST00000402697 PRAME P78395 Melanoma antigen preferentially expressed in tumors chr22 GO:0048585 Not Cancer Driver No 95 0.187 10 1 0.1 0
PRAP1 PRAP1 Q96NZ9 Proline-rich acidic protein 1 chr10 GO:0048585 Not Cancer Driver No 14 0.093 124 13 0.105 0
PRDM14 PRDM14 Q9GZV8 PR domain zinc finger protein 14 chr8 GO:0048585 Not Cancer Driver No 122 0.214 179 37 0.207 0
PRDX2 PRDX2 P32119 Peroxiredoxin-2 chr19 GO:0048585 Not Cancer Driver No 24 0.121 30 4 0.133 0
PRELID1 PRELID1 Q9Y255 PRELI domain-containing protein 1, mitochondrial chr5 GO:0048585 Not Cancer Driver No 21 0.096 44 2 0.045 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0048585 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 GO:0048585 Census Yes 53 0.151 24 0 0.0 2
PRKACB_ENST00000370689 PRKACB P22694 cAMP-dependent protein kinase catalytic subunit beta chr1 GO:0048585 Not Cancer Driver No 50 0.142 26 6 0.231 4
PRKCB_ENST00000321728 PRKCB P05771 Protein kinase C beta type chr16 GO:0048585 Census, Compendium Yes 205 0.306 148 40 0.27 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0048585 Compendium Yes 79 0.117 43 9 0.209 0
PRKCQ PRKCQ Q04759 Protein kinase C theta type chr10 GO:0048585 Not Cancer Driver No 147 0.208 28 9 0.321 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0048585 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRKG1_ENST00000401604 PRKG1 Q13976 cGMP-dependent protein kinase 1 chr10 GO:0048585 Not Cancer Driver No 167 0.249 93 22 0.237 1
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0048585 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRNP PRNP P04156 Major prion protein chr20 GO:0048585 Not Cancer Driver No 36 0.142 115 7 0.061 18
PROS1 PROS1 P07225 Vitamin K-dependent protein S chr3 GO:0048585 Not Cancer Driver No 178 0.263 11 3 0.273 89
PSCA PSCA O43653 Prostate stem cell antigen chr8 GO:0048585 Not Cancer Driver No 9 0.079 0 0 0.0 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0048585 Not Cancer Driver No 61 0.131 134 21 0.157 96
PSMA1_ENST00000396394 PSMA1 P25786 Proteasome subunit alpha type-1 chr11 GO:0048585 Not Cancer Driver No 48 0.183 51 9 0.176 0
PSMB4 PSMB4 P28070 Proteasome subunit beta type-4 chr1 GO:0048585 Not Cancer Driver No 23 0.087 18 2 0.111 0
PSMD10 PSMD10 O75832 26S proteasome non-ATPase regulatory subunit 10 chrX GO:0048585 Not Cancer Driver No 20 0.088 53 5 0.094 0
PTCH1 PTCH1 Q13635 Protein patched homolog 1 chr9 GO:0048585 Census, Compendium Yes 243 0.168 382 67 0.175 18
PTCH2 PTCH2 Q9Y6C5 Protein patched homolog 2 chr1 GO:0048585 Not Cancer Driver No 159 0.132 130 15 0.115 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0048585 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTGIR PTGIR P43119 Prostacyclin receptor chr19 GO:0048585 Not Cancer Driver No 40 0.104 47 4 0.085 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0048585 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:0048585 Not Cancer Driver No 49 0.113 140 25 0.179 0
PTPN12 PTPN12 Q05209 Tyrosine-protein phosphatase non-receptor type 12 chr7 GO:0048585 Not Cancer Driver No 102 0.131 516 60 0.116 0
PTPN18 PTPN18 Q99952 Tyrosine-protein phosphatase non-receptor type 18 chr2 GO:0048585 Not Cancer Driver No 51 0.111 138 8 0.058 0
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:0048585 Not Cancer Driver No 57 0.137 120 14 0.117 0
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0048585 Not Cancer Driver No 141 0.175 364 62 0.17 4
PTPN3 PTPN3 P26045 Tyrosine-protein phosphatase non-receptor type 3 chr9 GO:0048585 Not Cancer Driver No 139 0.152 214 28 0.131 0
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:0048585 Census, Compendium Yes 73 0.123 192 25 0.13 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0048585 Census, Compendium Yes 315 0.241 462 107 0.232 0
PTPRD PTPRD P23468 Receptor-type tyrosine-protein phosphatase delta chr9 GO:0048585 Census, Compendium Yes 577 0.302 747 219 0.293 0
PTPRE PTPRE P23469 Receptor-type tyrosine-protein phosphatase epsilon chr10 GO:0048585 Not Cancer Driver No 122 0.174 97 13 0.134 0
PTPRJ PTPRJ Q12913 Receptor-type tyrosine-protein phosphatase eta chr11 GO:0048585 Not Cancer Driver No 184 0.138 401 61 0.152 0
PTPRO PTPRO Q16827 Receptor-type tyrosine-protein phosphatase O chr12 GO:0048585 Not Cancer Driver No 204 0.168 137 34 0.248 0
PTPRR PTPRR Q15256 Receptor-type tyrosine-protein phosphatase R chr12 GO:0048585 Not Cancer Driver No 172 0.262 73 28 0.384 0
PTPRS PTPRS Q13332 Receptor-type tyrosine-protein phosphatase S chr19 GO:0048585 Not Cancer Driver No 250 0.128 829 111 0.134 0
PTPRT_ENST00000373187 PTPRT O14522 Receptor-type tyrosine-protein phosphatase T chr20 GO:0048585 Census, Compendium Yes 535 0.371 299 125 0.418 0
PTTG1IP PTTG1IP P53801 Pituitary tumor-transforming gene 1 protein-interacting protein chr21 GO:0048585 Not Cancer Driver No 23 0.128 30 9 0.3 0
PVRIG PVRIG Q6DKI7 Transmembrane protein PVRIG chr7 GO:0048585 Not Cancer Driver No 41 0.126 173 28 0.162 0
PXDN PXDN Q92626 Peroxidasin homolog chr2 GO:0048585 Not Cancer Driver No 332 0.224 307 77 0.251 1
PYCR1_ENST00000329875 PYCR1 P32322 Pyrroline-5-carboxylate reductase 1, mitochondrial chr17 GO:0048585 Not Cancer Driver No 31 0.097 67 10 0.149 9
PYDC1 PYDC1 Q8WXC3 Pyrin domain-containing protein 1 chr16 GO:0048585 Not Cancer Driver No 28 0.315 0 0 0.0 0
PYDC2 PYDC2 Q56P42 Pyrin domain-containing protein 2 chr3 GO:0048585 Not Cancer Driver No 20 0.206 26 5 0.192 0
QARS QARS1 P47897 Glutamine--tRNA ligase chr3 GO:0048585 Not Cancer Driver No 101 0.13 106 16 0.151 4
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 GO:0048585 Not Cancer Driver No 27 0.13 11 0 0.0 4
RABGEF1_ENST00000284957 RABGEF1 Q9UJ41 Rab5 GDP/GTP exchange factor chr7 GO:0048585 Not Cancer Driver No 73 0.149 175 35 0.2 0
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:0048585 Not Cancer Driver No 34 0.107 13 0 0.0 0
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 GO:0048585 Census, Compendium Yes 89 0.137 169 38 0.225 22
RANBP9 RANBP9 Q96S59 Ran-binding protein 9 chr6 GO:0048585 Not Cancer Driver No 73 0.1 413 30 0.073 0
RASIP1 RASIP1 Q5U651 Ras-interacting protein 1 chr19 GO:0048585 Not Cancer Driver No 73 0.076 505 48 0.095 0
RASSF2 RASSF2 P50749 Ras association domain-containing protein 2 chr20 GO:0048585 Not Cancer Driver No 90 0.276 126 44 0.349 0
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 GO:0048585 Census, Compendium Yes 140 0.151 282 32 0.113 22
RBL1 RBL1 P28749 Retinoblastoma-like protein 1 chr20 GO:0048585 Not Cancer Driver No 140 0.131 335 41 0.122 0
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 GO:0048585 Not Cancer Driver No 158 0.139 796 115 0.144 0
RC3H2_ENST00000357244 RC3H2 Q9HBD1 Roquin-2 chr9 GO:0048585 Not Cancer Driver No 128 0.107 703 81 0.115 0
RCAN1_ENST00000313806 RCAN1 P53805 Calcipressin-1 chr21 GO:0048585 Not Cancer Driver No 26 0.103 104 7 0.067 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:0048585 Compendium Yes 75 0.136 400 48 0.12 0
RFFL_ENST00000394597 RFFL Q8WZ73 E3 ubiquitin-protein ligase rififylin chr17 GO:0048585 Not Cancer Driver No 50 0.138 150 21 0.14 0
RFX4_ENST00000392842 RFX4 Q33E94 Transcription factor RFX4 chr12 GO:0048585 Not Cancer Driver No 124 0.169 308 47 0.153 0
RGMA_ENST00000329082 RGMA Q96B86 Repulsive guidance molecule A chr15 GO:0048585 Not Cancer Driver No 63 0.14 105 13 0.124 0
RGS13_ENST00000391995 RGS13 O14921 Regulator of G-protein signaling 13 chr1 GO:0048585 Not Cancer Driver No 32 0.201 17 6 0.353 0
RGS14 RGS14 O43566 Regulator of G-protein signaling 14 chr5 GO:0048585 Not Cancer Driver No 57 0.101 309 37 0.12 0
RGS2 RGS2 P41220 Regulator of G-protein signaling 2 chr1 GO:0048585 Not Cancer Driver No 30 0.142 50 4 0.08 0
RGS4_ENST00000367909 RGS4 P49798 Regulator of G-protein signaling 4 chr1 GO:0048585 Not Cancer Driver No 68 0.332 5 4 0.8 0
RHBDF2 RHBDF2 Q6PJF5 Inactive rhomboid protein 2 chr17 GO:0048585 Not Cancer Driver No 93 0.109 284 36 0.127 2
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0048585 Census, Compendium Yes 99 0.513 46 13 0.283 2
RIN3 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 GO:0048585 Not Cancer Driver No 137 0.139 417 61 0.146 0
RIOK3 RIOK3 O14730 Serine/threonine-protein kinase RIO3 chr18 GO:0048585 Not Cancer Driver No 58 0.112 225 21 0.093 0
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:0048585 Compendium Yes 82 0.122 277 39 0.141 4
RIPOR2_ENST00000259698 RIPOR2 Q9Y4F9 Rho family-interacting cell polarization regulator 2 chr6 GO:0048585 Not Cancer Driver No 131 0.123 421 76 0.181 0
RNF113A RNF113A O15541 E3 ubiquitin-protein ligase RNF113A chrX GO:0048585 Not Cancer Driver No 61 0.178 226 51 0.226 0
RNF115 RNF115 Q9Y4L5 E3 ubiquitin-protein ligase RNF115 chr1 GO:0048585 Not Cancer Driver No 30 0.099 136 14 0.103 0
RNF125 RNF125 Q96EQ8 E3 ubiquitin-protein ligase RNF125 chr18 GO:0048585 Not Cancer Driver No 35 0.151 26 1 0.038 3
RNF126 RNF126 Q9BV68 E3 ubiquitin-protein ligase RNF126 chr19 GO:0048585 Not Cancer Driver No 33 0.106 182 22 0.121 0
RNF152 RNF152 Q8N8N0 E3 ubiquitin-protein ligase RNF152 chr18 GO:0048585 Not Cancer Driver No 61 0.3 34 11 0.324 0
RNF157 RNF157 Q96PX1 E3 ubiquitin ligase RNF157 chr17 GO:0048585 Not Cancer Driver No 76 0.112 375 39 0.104 0
RNF213 RNF213 Q63HN8 E3 ubiquitin-protein ligase RNF213 chr17 GO:0048585 Census, Compendium Yes 560 0.108 623 75 0.12 3
RNF26 RNF26 Q9BY78 E3 ubiquitin-protein ligase RNF26 chr11 GO:0048585 Not Cancer Driver No 44 0.102 71 7 0.099 0
RNF34_ENST00000361234 RNF34 Q969K3 E3 ubiquitin-protein ligase RNF34 chr12 GO:0048585 Not Cancer Driver No 30 0.081 112 7 0.062 0
ROBO1 ROBO1 Q9Y6N7 Roundabout homolog 1 chr3 GO:0048585 Not Cancer Driver No 353 0.214 1122 234 0.209 0
ROBO2_ENST00000461745 ROBO2 Q9HCK4 Roundabout homolog 2 chr3 GO:0048585 Census Yes 407 0.295 874 259 0.296 2
RPGRIP1L_ENST00000379925 RPGRIP1L Q68CZ1 Protein fantom chr16 GO:0048585 Not Cancer Driver No 177 0.135 586 94 0.16 8
RPH3AL RPH3AL Q9UNE2 Rab effector Noc2 chr17 GO:0048585 Not Cancer Driver No 40 0.127 162 20 0.123 0
RPS19_ENST00000600467 RPS19 P39019 40S ribosomal protein S19 chr19 GO:0048585 Not Cancer Driver No 15 0.103 61 3 0.049 23
RPS6KA6_ENST00000262752 RPS6KA6 Q9UK32 Ribosomal protein S6 kinase alpha-6 chrX GO:0048585 Not Cancer Driver No 180 0.242 136 36 0.265 0
RPS6KB1 RPS6KB1 P23443 Ribosomal protein S6 kinase beta-1 chr17 GO:0048585 Not Cancer Driver No 45 0.086 226 26 0.115 0
RRM2B RRM2B Q7LG56 Ribonucleoside-diphosphate reductase subunit M2 B chr8 GO:0048585 Not Cancer Driver No 46 0.131 32 5 0.156 9
RRN3 RRN3 Q9NYV6 RNA polymerase I-specific transcription initiation factor RRN3 chr16 GO:0048585 Not Cancer Driver No 66 0.101 115 15 0.13 0
RTEL1_ENST00000370018 RTEL1 Q9NZ71 Regulator of telomere elongation helicase 1 chr20 GO:0048585 Not Cancer Driver No 144 0.118 474 64 0.135 14
RTN4R RTN4R Q9BZR6 Reticulon-4 receptor chr22 GO:0048585 Not Cancer Driver No 38 0.08 148 17 0.115 5
RTN4RL1 RTN4RL1 Q86UN2 Reticulon-4 receptor-like 1 chr17 GO:0048585 Not Cancer Driver No 56 0.127 142 12 0.085 0
RUNX2_ENST00000647337 RUNX2 Q13950 Runt-related transcription factor 2 chr6 GO:0048585 Not Cancer Driver No 83 0.159 447 73 0.163 47
RYK_ENST00000623711 RYK P34925 Tyrosine-protein kinase RYK chr3 GO:0048585 Not Cancer Driver No 55 0.091 85 4 0.047 0
S1PR2 S1PR2 O95136 Sphingosine 1-phosphate receptor 2 chr19 GO:0048585 Not Cancer Driver No 38 0.108 16 3 0.188 2
SAMHD1 SAMHD1 Q9Y3Z3 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 chr20 GO:0048585 Not Cancer Driver No 104 0.166 91 14 0.154 13
SAMSN1_ENST00000400566 SAMSN1 Q9NSI8 SAM domain-containing protein SAMSN-1 chr21 GO:0048585 Not Cancer Driver No 112 0.3 291 85 0.292 0
SARM1 SARM1 Q6SZW1 NAD(+) hydrolase SARM1 chr17 GO:0048585 Not Cancer Driver No 36 0.05 80 4 0.05 0
SCAI_ENST00000336505 SCAI Q8N9R8 Protein SCAI chr9 GO:0048585 Not Cancer Driver No 95 0.157 117 13 0.111 0
SCRT2 SCRT2 Q9NQ03 Transcriptional repressor scratch 2 chr20 GO:0048585 Not Cancer Driver No 19 0.062 168 4 0.024 0
SEC14L1_ENST00000436233 SEC14L1 Q92503 SEC14-like protein 1 chr17 GO:0048585 Not Cancer Driver No 104 0.145 82 16 0.195 0
SELENOS SELENOS Q9BQE4 Selenoprotein S chr15 GO:0048585 Not Cancer Driver No 7 0.037 122 6 0.049 0
SEMA3A SEMA3A Q14563 Semaphorin-3A chr7 GO:0048585 Not Cancer Driver No 195 0.253 164 46 0.28 10
SEMA3B_ENST00000616701 SEMA3B Q13214 Semaphorin-3B chr3 GO:0048585 Not Cancer Driver No 46 0.061 145 8 0.055 0
SEMA3C SEMA3C Q99985 Semaphorin-3C chr7 GO:0048585 Not Cancer Driver No 136 0.181 111 23 0.207 0
SEMA3D SEMA3D O95025 Semaphorin-3D chr7 GO:0048585 Not Cancer Driver No 191 0.246 101 44 0.436 0
SEMA3E SEMA3E O15041 Semaphorin-3E chr7 GO:0048585 Not Cancer Driver No 195 0.252 86 27 0.314 0
SEMA3F SEMA3F Q13275 Semaphorin-3F chr3 GO:0048585 Not Cancer Driver No 114 0.145 194 27 0.139 0
SEMA3G SEMA3G Q9NS98 Semaphorin-3G chr3 GO:0048585 Not Cancer Driver No 104 0.133 206 28 0.136 0
SEMA4A_ENST00000355014 SEMA4A Q9H3S1 Semaphorin-4A chr1 GO:0048585 Not Cancer Driver No 123 0.162 122 26 0.213 4
SEMA4B SEMA4B Q9NPR2 Semaphorin-4B chr15 GO:0048585 Not Cancer Driver No 94 0.112 107 17 0.159 0
SEMA4C SEMA4C Q9C0C4 Semaphorin-4C chr2 GO:0048585 Not Cancer Driver No 111 0.133 149 27 0.181 0
SEMA4D SEMA4D Q92854 Semaphorin-4D chr9 GO:0048585 Not Cancer Driver No 117 0.136 132 15 0.114 0
SEMA4F SEMA4F O95754 Semaphorin-4F chr2 GO:0048585 Not Cancer Driver No 113 0.147 140 16 0.114 0
SEMA4G_ENST00000370250 SEMA4G Q9NTN9 Semaphorin-4G chr10 GO:0048585 Not Cancer Driver No 95 0.113 285 30 0.105 0
SEMA5A SEMA5A Q13591 Semaphorin-5A chr5 GO:0048585 Not Cancer Driver No 266 0.248 23 4 0.174 0
SEMA5B_ENST00000616742 SEMA5B Q9P283 Semaphorin-5B chr3 GO:0048585 Not Cancer Driver No 229 0.199 162 16 0.099 0
SEMA6A_ENST00000510263 SEMA6A Q9H2E6 Semaphorin-6A chr5 GO:0048585 Not Cancer Driver No 136 0.132 456 72 0.158 0
SEMA6B SEMA6B Q9H3T3 Semaphorin-6B chr19 GO:0048585 Not Cancer Driver No 77 0.087 340 26 0.076 0
SEMA6C SEMA6C Q9H3T2 Semaphorin-6C chr1 GO:0048585 Not Cancer Driver No 116 0.125 411 27 0.066 0
SEMA6D_ENST00000536845 SEMA6D Q8NFY4 Semaphorin-6D chr15 GO:0048585 Not Cancer Driver No 212 0.198 475 99 0.208 0
SEMA7A SEMA7A O75326 Semaphorin-7A chr15 GO:0048585 Not Cancer Driver No 81 0.122 150 21 0.14 0
SERPINB2_ENST00000299502 SERPINB2 P05120 Plasminogen activator inhibitor 2 chr18 GO:0048585 Not Cancer Driver No 100 0.241 29 7 0.241 0
SERPINB3 SERPINB3 P29508 Serpin B3 chr18 GO:0048585 Not Cancer Driver No 142 0.364 47 28 0.596 0
SERPINB4 SERPINB4 P48594 Serpin B4 chr18 GO:0048585 Not Cancer Driver No 120 0.308 48 18 0.375 0
SERPINB9 SERPINB9 P50453 Serpin B9 chr6 GO:0048585 Not Cancer Driver No 64 0.17 22 2 0.091 0
SERPINE1 SERPINE1 P05121 Plasminogen activator inhibitor 1 chr7 GO:0048585 Not Cancer Driver No 78 0.194 7 2 0.286 0
SERPINE2_ENST00000258405 SERPINE2 P07093 Glia-derived nexin chr2 GO:0048585 Not Cancer Driver No 62 0.156 0 0 0.0 0
SERPINF2_ENST00000382061 SERPINF2 P08697 Alpha-2-antiplasmin chr17 GO:0048585 Not Cancer Driver No 62 0.126 112 21 0.188 1
SERPING1 SERPING1 P05155 Plasma protease C1 inhibitor chr11 GO:0048585 Not Cancer Driver No 74 0.148 113 13 0.115 40
SESN1_ENST00000356644 SESN1 Q9Y6P5 Sestrin-1 chr6 GO:0048585 Not Cancer Driver No 45 0.091 48 4 0.083 0
SESN2 SESN2 P58004 Sestrin-2 chr1 GO:0048585 Not Cancer Driver No 74 0.154 147 26 0.177 0
SESN3 SESN3 P58005 Sestrin-3 chr11 GO:0048585 Not Cancer Driver No 84 0.171 44 4 0.091 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0048585 Not Cancer Driver No 40 0.127 39 7 0.179 0
SFRP2 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:0048585 Not Cancer Driver No 47 0.159 1 0 0.0 0
SFRP4 SFRP4 Q6FHJ7 Secreted frizzled-related protein 4 chr7 GO:0048585 Census Yes 81 0.234 68 22 0.324 0
SFRP5 SFRP5 Q5T4F7 Secreted frizzled-related protein 5 chr10 GO:0048585 Not Cancer Driver No 26 0.082 7 3 0.429 0
SGTA SGTA O43765 Small glutamine-rich tetratricopeptide repeat-containing protein alpha chr19 GO:0048585 Not Cancer Driver No 38 0.121 159 23 0.145 0
SH2B3 SH2B3 Q9UQQ2 SH2B adapter protein 3 chr12 GO:0048585 Census, Compendium Yes 48 0.083 333 19 0.057 0
SH2D1A SH2D1A O60880 SH2 domain-containing protein 1A chrX GO:0048585 Not Cancer Driver No 40 0.312 24 8 0.333 19
SH3RF2 SH3RF2 Q8TEC5 E3 ubiquitin-protein ligase SH3RF2 chr5 GO:0048585 Not Cancer Driver No 151 0.207 455 101 0.222 0
SHANK2_ENST00000601538 SHANK2 Q9UPX8 SH3 and multiple ankyrin repeat domains protein 2 chr11 GO:0048585 Not Cancer Driver No 303 0.164 1379 262 0.19 0
SHISA2 SHISA2 Q6UWI4 Protein shisa-2 homolog chr13 GO:0048585 Not Cancer Driver No 44 0.149 143 29 0.203 0
SIGIRR_ENST00000397632 SIGIRR Q6IA17 Single Ig IL-1-related receptor chr11 GO:0048585 Not Cancer Driver No 27 0.066 85 4 0.047 0
SIGLEC10 SIGLEC10 Q96LC7 Sialic acid-binding Ig-like lectin 10 chr19 GO:0048585 Not Cancer Driver No 172 0.247 310 82 0.265 0
SIRPA_ENST00000400068 SIRPA P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 GO:0048585 Census, Compendium Yes 96 0.19 281 51 0.181 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0048585 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0048585 Not Cancer Driver No 56 0.144 85 17 0.2 0
SKI SKI P12755 Ski oncogene chr1 GO:0048585 Census Yes 44 0.06 432 26 0.06 14
SLA2 SLA2 Q9H6Q3 Src-like-adapter 2 chr20 GO:0048585 Not Cancer Driver No 32 0.123 43 9 0.209 0
SLAMF1_ENST00000302035 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 GO:0048585 Not Cancer Driver No 82 0.245 64 10 0.156 0
SLAMF8 SLAMF8 Q9P0V8 SLAM family member 8 chr1 GO:0048585 Not Cancer Driver No 63 0.221 20 2 0.1 0
SLC12A2 SLC12A2 P55011 Solute carrier family 12 member 2 chr5 GO:0048585 Not Cancer Driver No 141 0.116 297 18 0.061 8
SLC24A4 SLC24A4 Q8NFF2 Sodium/potassium/calcium exchanger 4 chr14 GO:0048585 Not Cancer Driver No 121 0.195 85 14 0.165 2
SLC25A31 SLC25A31 Q9H0C2 ADP/ATP translocase 4 chr4 GO:0048585 Not Cancer Driver No 68 0.216 8 0 0.0 0
SLC25A4 SLC25A4 P12235 ADP/ATP translocase 1 chr4 GO:0048585 Not Cancer Driver No 24 0.081 0 0 0.0 9
SLC25A5 SLC25A5 P05141 ADP/ATP translocase 2 chrX GO:0048585 Not Cancer Driver No 41 0.138 0 0 0.0 0
SLC25A6 SLC25A6 P12236 ADP/ATP translocase 3 chrX GO:0048585 Not Cancer Driver No 41 0.138 0 0 0.0 0
SLC27A4 SLC27A4 Q6P1M0 Long-chain fatty acid transport protein 4 chr9 GO:0048585 Not Cancer Driver No 83 0.129 27 3 0.111 5
SLC2A10 SLC2A10 O95528 Solute carrier family 2, facilitated glucose transporter member 10 chr20 GO:0048585 Not Cancer Driver No 98 0.181 72 15 0.208 8
SLC30A10 SLC30A10 Q6XR72 Zinc transporter 10 chr1 GO:0048585 Not Cancer Driver No 68 0.14 61 10 0.164 2
SLC35F6 SLC35F6 Q8N357 Solute carrier family 35 member F6 chr2 GO:0048585 Not Cancer Driver No 33 0.089 13 0 0.0 0
SLC6A3 SLC6A3 Q01959 Sodium-dependent dopamine transporter chr5 GO:0048585 Not Cancer Driver No 150 0.242 31 8 0.258 2
SLC9A3R1 SLC9A3R1 O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 chr17 GO:0048585 Not Cancer Driver No 19 0.053 318 16 0.05 4
SLIT1 SLIT1 O75093 Slit homolog 1 protein chr10 GO:0048585 Not Cancer Driver No 221 0.144 36 1 0.028 0
SLIT2 SLIT2 O94813 Slit homolog 2 protein chr4 GO:0048585 Not Cancer Driver No 428 0.28 31 13 0.419 0
SLIT3_ENST00000519560 SLIT3 O75094 Slit homolog 3 protein chr5 GO:0048585 Not Cancer Driver No 351 0.23 40 9 0.225 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0048585 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0048585 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMAD6 SMAD6 O43541 Mothers against decapentaplegic homolog 6 chr15 GO:0048585 Not Cancer Driver No 38 0.077 248 7 0.028 7
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0048585 Not Cancer Driver No 40 0.094 139 0 0.0 0
SMARCA4 SMARCA4 P51532 Transcription activator BRG1 chr19 GO:0048585 Census, Compendium Yes 349 0.212 1072 195 0.182 5
SMPD1 SMPD1 P17405 Sphingomyelin phosphodiesterase chr11 GO:0048585 Not Cancer Driver No 93 0.147 51 4 0.078 111
SMPDL3B SMPDL3B Q92485 Acid sphingomyelinase-like phosphodiesterase 3b chr1 GO:0048585 Not Cancer Driver No 61 0.134 22 7 0.318 0
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 GO:0048585 Not Cancer Driver No 52 0.197 97 11 0.113 0
SNAI2_ENST00000020945 SNAI2 O43623 Zinc finger protein SNAI2 chr8 GO:0048585 Not Cancer Driver No 52 0.194 52 9 0.173 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0048585 Not Cancer Driver No 21 0.15 107 13 0.121 5
SNX25 SNX25 Q9H3E2 Sorting nexin-25 chr4 GO:0048585 Not Cancer Driver No 101 0.12 114 10 0.088 0
SNX5_ENST00000377759 SNX5 Q9Y5X3 Sorting nexin-5 chr20 GO:0048585 Not Cancer Driver No 33 0.082 91 13 0.143 0
SNX6 SNX6 Q9UNH7 Sorting nexin-6 chr14 GO:0048585 Not Cancer Driver No 33 0.081 85 7 0.082 0
SOCS1 SOCS1 O15524 Suppressor of cytokine signaling 1 chr16 GO:0048585 Census, Compendium Yes 22 0.104 66 3 0.045 2
SOCS2_ENST00000536696 SOCS2 O14508 Suppressor of cytokine signaling 2 chr12 GO:0048585 Not Cancer Driver No 32 0.162 61 2 0.033 0
SOCS3 SOCS3 O14543 Suppressor of cytokine signaling 3 chr17 GO:0048585 Not Cancer Driver No 27 0.12 111 14 0.126 0
SOCS4_ENST00000555846 SOCS4 Q8WXH5 Suppressor of cytokine signaling 4 chr14 GO:0048585 Not Cancer Driver No 43 0.098 136 13 0.096 0
SOCS5 SOCS5 O75159 Suppressor of cytokine signaling 5 chr2 GO:0048585 Not Cancer Driver No 84 0.157 297 46 0.155 0
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0048585 Not Cancer Driver No 32 0.144 25 5 0.2 0
SOX17 SOX17 Q9H6I2 Transcription factor SOX-17 chr8 GO:0048585 Compendium Yes 81 0.196 378 59 0.156 2
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0048585 Not Cancer Driver No 46 0.17 187 34 0.182 0
SPINK1 SPINK1 P00995 Serine protease inhibitor Kazal-type 1 chr5 GO:0048585 Not Cancer Driver No 14 0.177 0 0 0.0 3
SPINK5_ENST00000256084 SPINK5 Q9NQ38 Serine protease inhibitor Kazal-type 5 chr5 GO:0048585 Not Cancer Driver No 168 0.158 590 102 0.173 0
SPP1 SPP1 P10451 Osteopontin chr4 GO:0048585 Not Cancer Driver No 56 0.178 296 54 0.182 0
SPRED1 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 GO:0048585 Not Cancer Driver No 71 0.16 194 35 0.18 2
SPRED2 SPRED2 Q7Z698 Sprouty-related, EVH1 domain-containing protein 2 chr2 GO:0048585 Not Cancer Driver No 73 0.175 228 43 0.189 0
SPRED3_ENST00000586301 SPRED3 Q2MJR0 Sprouty-related, EVH1 domain-containing protein 3 chr19 GO:0048585 Not Cancer Driver No 31 0.076 207 15 0.072 0
SPRY1 SPRY1 O43609 Protein sprouty homolog 1 chr4 GO:0048585 Not Cancer Driver No 46 0.144 168 26 0.155 0
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 GO:0048585 Not Cancer Driver No 46 0.146 169 29 0.172 1
SPRY3 SPRY3 O43610 Protein sprouty homolog 3 chrX GO:0048585 Not Cancer Driver No 96 0.333 135 40 0.296 0
SPRY4_ENST00000434127 SPRY4 Q9C004 Protein sprouty homolog 4 chr5 GO:0048585 Not Cancer Driver No 34 0.114 134 20 0.149 7
SPX SPX Q9BT56 Spexin chr12 GO:0048585 Not Cancer Driver No 22 0.19 40 8 0.2 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0048585 Census Yes 53 0.099 130 11 0.085 1
SSTR4 SSTR4 P31391 Somatostatin receptor type 4 chr20 GO:0048585 Not Cancer Driver No 129 0.332 39 12 0.308 0
ST6GAL1 ST6GAL1 P15907 Beta-galactoside alpha-2,6-sialyltransferase 1 chr3 GO:0048585 Not Cancer Driver No 55 0.135 34 8 0.235 0
STAMBP_ENST00000339566 STAMBP O95630 STAM-binding protein chr2 GO:0048585 Not Cancer Driver No 51 0.12 139 16 0.115 6
STAP1_ENST00000396225 STAP1 Q9ULZ2 Signal-transducing adaptor protein 1 chr4 GO:0048585 Not Cancer Driver No 66 0.224 103 18 0.175 0
STAT2 STAT2 P52630 Signal transducer and activator of transcription 2 chr12 GO:0048585 Not Cancer Driver No 90 0.106 178 22 0.124 2
STAT6_ENST00000543873 STAT6 P42226 Signal transducer and activator of transcription 6 chr12 GO:0048585 Census, Compendium Yes 106 0.125 325 44 0.135 0
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:0048585 Census, Compendium Yes 75 0.173 135 14 0.104 9
STMN1_ENST00000357865 STMN1 P16949 Stathmin chr1 GO:0048585 Not Cancer Driver No 15 0.101 149 15 0.101 0
STMN3 STMN3 Q9NZ72 Stathmin-3 chr20 GO:0048585 Not Cancer Driver No 26 0.144 152 25 0.164 0
STRADB STRADB Q9C0K7 STE20-related kinase adapter protein beta chr2 GO:0048585 Not Cancer Driver No 53 0.127 84 7 0.083 0
STRN3 STRN3 Q13033 Striatin-3 chr14 GO:0048585 Not Cancer Driver No 93 0.117 366 42 0.115 0
SUFU SUFU Q9UMX1 Suppressor of fused homolog chr10 GO:0048585 Census Yes 55 0.114 199 19 0.095 2
SULF1_ENST00000458141 SULF1 Q8IWU6 Extracellular sulfatase Sulf-1 chr8 GO:0048585 Not Cancer Driver No 246 0.282 269 71 0.264 0
SULF2_ENST00000484875 SULF2 Q8IWU5 Extracellular sulfatase Sulf-2 chr20 GO:0048585 Not Cancer Driver No 145 0.167 142 18 0.127 0
SUSD4 SUSD4 Q5VX71 Sushi domain-containing protein 4 chr1 GO:0048585 Not Cancer Driver No 85 0.173 134 27 0.201 0
SVIP SVIP Q8NHG7 Small VCP/p97-interacting protein chr11 GO:0048585 Not Cancer Driver No 16 0.208 77 16 0.208 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0048585 Census Yes 96 0.151 131 27 0.206 5
SYNJ2BP SYNJ2BP P57105 Synaptojanin-2-binding protein chr14 GO:0048585 Not Cancer Driver No 27 0.186 12 4 0.333 0
SYT11 SYT11 Q9BT88 Synaptotagmin-11 chr1 GO:0048585 Not Cancer Driver No 64 0.148 105 23 0.219 0
SYVN1 SYVN1 Q86TM6 E3 ubiquitin-protein ligase synoviolin chr11 GO:0048585 Not Cancer Driver No 63 0.102 284 32 0.113 0
SZT2_ENST00000634258 SZT2 Q5T011 KICSTOR complex protein SZT2 chr1 GO:0048585 Not Cancer Driver No 381 0.111 1292 161 0.125 1
TAF9 TAF9 Q16594 Transcription initiation factor TFIID subunit 9 chr5 GO:0048585 Not Cancer Driver No 25 0.095 203 19 0.094 0
TAF9B TAF9B Q9HBM6 Transcription initiation factor TFIID subunit 9B chrX GO:0048585 Not Cancer Driver No 48 0.191 189 34 0.18 0
TAOK3 TAOK3 Q9H2K8 Serine/threonine-protein kinase TAO3 chr12 GO:0048585 Not Cancer Driver No 123 0.137 494 64 0.13 0
TARBP2 TARBP2 Q15633 RISC-loading complex subunit TARBP2 chr12 GO:0048585 Not Cancer Driver No 45 0.123 203 22 0.108 0
TBC1D10C TBC1D10C Q8IV04 Carabin chr11 GO:0048585 Not Cancer Driver No 58 0.13 192 32 0.167 0
TBX18 TBX18 O95935 T-box transcription factor TBX18 chr6 GO:0048585 Not Cancer Driver No 156 0.257 356 94 0.264 2
TBX2 TBX2 Q13207 T-box transcription factor TBX2 chr17 GO:0048585 Not Cancer Driver No 74 0.104 401 36 0.09 1
TBX20 TBX20 Q9UMR3 T-box transcription factor TBX20 chr7 GO:0048585 Not Cancer Driver No 117 0.262 201 54 0.269 2
TBX21 TBX21 Q9UL17 T-box transcription factor TBX21 chr17 GO:0048585 Not Cancer Driver No 70 0.131 348 50 0.144 0
TCF21 TCF21 O43680 Transcription factor 21 chr6 GO:0048585 Not Cancer Driver No 55 0.307 120 40 0.333 0
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 GO:0048585 Not Cancer Driver No 33 0.061 361 20 0.055 0
TERT TERT O14746 Telomerase reverse transcriptase chr5 GO:0048585 Census Yes 110 0.097 212 16 0.075 31
TFIP11_ENST00000407148 TFIP11 Q9UBB9 Tuftelin-interacting protein 11 chr22 GO:0048585 Not Cancer Driver No 87 0.104 331 39 0.118 0
THBD THBD P07204 Thrombomodulin chr20 GO:0048585 Not Cancer Driver No 39 0.068 51 3 0.059 9
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0048585 Not Cancer Driver No 188 0.161 320 58 0.181 0
THOC1 THOC1 Q96FV9 THO complex subunit 1 chr18 GO:0048585 Not Cancer Driver No 55 0.084 280 26 0.093 0
THOC5_ENST00000397872 THOC5 Q13769 THO complex subunit 5 homolog chr22 GO:0048585 Not Cancer Driver No 88 0.129 173 25 0.145 0
THY1 THY1 P04216 Thy-1 membrane glycoprotein chr11 GO:0048585 Not Cancer Driver No 24 0.149 5 0 0.0 0
TIMP3 TIMP3 P35625 Metalloproteinase inhibitor 3 chr22 GO:0048585 Not Cancer Driver No 43 0.204 3 1 0.333 5
TKFC TKFC Q3LXA3 Triokinase/FMN cyclase chr11 GO:0048585 Not Cancer Driver No 66 0.115 91 14 0.154 2
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0048585 Not Cancer Driver No 292 0.348 0 0 0.0 0
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:0048585 Not Cancer Driver No 99 0.124 1 0 0.0 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:0048585 Not Cancer Driver No 141 0.137 35 3 0.086 0
TMBIM1_ENST00000396809 TMBIM1 Q969X1 Protein lifeguard 3 chr2 GO:0048585 Not Cancer Driver No 30 0.096 83 8 0.096 0
TMBIM6_ENST00000549385 TMBIM6 P55061 Bax inhibitor 1 chr12 GO:0048585 Not Cancer Driver No 16 0.068 3 0 0.0 0
TMEM14A TMEM14A Q9Y6G1 Transmembrane protein 14A chr6 GO:0048585 Not Cancer Driver No 10 0.101 0 0 0.0 0
TMEM161A TMEM161A Q9NX61 Transmembrane protein 161A chr19 GO:0048585 Not Cancer Driver No 49 0.102 22 8 0.364 0
TMEM25_ENST00000313236 TMEM25 Q86YD3 Transmembrane protein 25 chr11 GO:0048585 Not Cancer Driver No 50 0.137 128 11 0.086 0
TMSB4X_ENST00000380633 TMSB4X P62328 Thymosin beta-4 chrX GO:0048585 Census Yes 7 0.159 44 7 0.159 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0048585 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFAIP1 TNFAIP1 Q13829 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 chr17 GO:0048585 Not Cancer Driver No 35 0.111 39 5 0.128 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:0048585 Census, Compendium Yes 98 0.124 231 33 0.143 1
TNFAIP6 TNFAIP6 P98066 Tumor necrosis factor-inducible gene 6 protein chr2 GO:0048585 Not Cancer Driver No 62 0.224 13 5 0.385 0
TNFRSF14 TNFRSF14 Q92956 Tumor necrosis factor receptor superfamily member 14 chr1 GO:0048585 Census, Compendium Yes 33 0.117 54 8 0.148 0
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 GO:0048585 Not Cancer Driver No 48 0.104 229 28 0.122 0
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 GO:0048585 Not Cancer Driver No 28 0.153 1 0 0.0 0
TNIP1_ENST00000522226 TNIP1 Q15025 TNFAIP3-interacting protein 1 chr5 GO:0048585 Not Cancer Driver No 85 0.134 625 83 0.133 0
TNN TNN Q9UQP3 Tenascin-N chr1 GO:0048585 Not Cancer Driver No 426 0.328 637 231 0.363 0
TNR TNR Q92752 Tenascin-R chr1 GO:0048585 Not Cancer Driver No 496 0.365 358 128 0.358 0
TNS2_ENST00000314250 TNS2 Q63HR2 Tensin-2 chr12 GO:0048585 Not Cancer Driver No 132 0.094 799 63 0.079 0
TP63 TP63 Q9H3D4 Tumor protein 63 chr3 GO:0048585 Census, Compendium Yes 229 0.337 398 143 0.359 28
TPT1_ENST00000530705 TPT1 P13693 Translationally-controlled tumor protein chr13 GO:0048585 Not Cancer Driver No 17 0.099 43 6 0.14 0
TRAF3IP1 TRAF3IP1 Q8TDR0 TRAF3-interacting protein 1 chr2 GO:0048585 Not Cancer Driver No 75 0.109 507 60 0.118 4
TRAFD1_ENST00000412615 TRAFD1 O14545 TRAF-type zinc finger domain-containing protein 1 chr12 GO:0048585 Not Cancer Driver No 55 0.095 374 32 0.086 0
TRAIP TRAIP Q9BWF2 E3 ubiquitin-protein ligase TRAIP chr3 GO:0048585 Not Cancer Driver No 63 0.134 240 33 0.138 1
TRAP1 TRAP1 Q12931 Heat shock protein 75 kDa, mitochondrial chr16 GO:0048585 Not Cancer Driver No 74 0.105 110 11 0.1 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0048585 Not Cancer Driver No 43 0.187 27 2 0.074 1
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0048585 Not Cancer Driver No 26 0.083 98 10 0.102 18
TRIAP1 TRIAP1 O43715 TP53-regulated inhibitor of apoptosis 1 chr12 GO:0048585 Not Cancer Driver No 9 0.118 20 1 0.05 0
TRIB1 TRIB1 Q96RU8 Tribbles homolog 1 chr8 GO:0048585 Not Cancer Driver No 47 0.126 91 5 0.055 0
TRIM21 TRIM21 P19474 E3 ubiquitin-protein ligase TRIM21 chr11 GO:0048585 Not Cancer Driver No 85 0.179 49 7 0.143 0
TRIM27 TRIM27 P14373 Zinc finger protein RFP chr6 GO:0048585 Census Yes 59 0.115 87 11 0.126 0
TRIM32 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 GO:0048585 Not Cancer Driver No 82 0.126 87 10 0.115 3
TRIM38 TRIM38 O00635 E3 ubiquitin-protein ligase TRIM38 chr6 GO:0048585 Not Cancer Driver No 62 0.133 47 8 0.17 0
TRIM40_ENST00000376724 TRIM40 Q6P9F5 E3 ubiquitin ligase TRIM40 chr6 GO:0048585 Not Cancer Driver No 44 0.171 84 12 0.143 0
TRIM72 TRIM72 Q6ZMU5 Tripartite motif-containing protein 72 chr16 GO:0048585 Not Cancer Driver No 54 0.113 69 14 0.203 0
TSC2 TSC2 P49815 Tuberin chr16 GO:0048585 Census, Compendium Yes 192 0.106 563 50 0.089 53
TSG101 TSG101 Q99816 Tumor susceptibility gene 101 protein chr11 GO:0048585 Not Cancer Driver No 46 0.118 159 23 0.145 0
TSPAN6 TSPAN6 O43657 Tetraspanin-6 chrX GO:0048585 Not Cancer Driver No 34 0.139 0 0 0.0 0
TTLL12 TTLL12 Q14166 Tubulin--tyrosine ligase-like protein 12 chr22 GO:0048585 Not Cancer Driver No 69 0.107 100 6 0.06 0
TULP3_ENST00000448120 TULP3 O75386 Tubby-related protein 3 chr12 GO:0048585 Not Cancer Driver No 66 0.149 218 29 0.133 0
TWIST1 TWIST1 Q15672 Twist-related protein 1 chr7 GO:0048585 Not Cancer Driver No 23 0.114 132 11 0.083 7
TXN TXN P10599 Thioredoxin chr9 GO:0048585 Not Cancer Driver No 6 0.057 0 0 0.0 0
TXNDC12 TXNDC12 O95881 Thioredoxin domain-containing protein 12 chr1 GO:0048585 Not Cancer Driver No 21 0.122 44 6 0.136 0
TYRO3 TYRO3 Q06418 Tyrosine-protein kinase receptor TYRO3 chr15 GO:0048585 Not Cancer Driver No 119 0.134 197 17 0.086 0
UACA UACA Q9BZF9 Uveal autoantigen with coiled-coil domains and ankyrin repeats chr15 GO:0048585 Not Cancer Driver No 177 0.125 863 101 0.117 0
UBASH3A UBASH3A P57075 Ubiquitin-associated and SH3 domain-containing protein A chr21 GO:0048585 Not Cancer Driver No 101 0.153 27 8 0.296 0
UBASH3B UBASH3B Q8TF42 Ubiquitin-associated and SH3 domain-containing protein B chr11 GO:0048585 Not Cancer Driver No 86 0.133 73 6 0.082 0
UBQLN1 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 GO:0048585 Not Cancer Driver No 64 0.109 543 58 0.107 0
UBXN1_ENST00000301935 UBXN1 Q04323 UBX domain-containing protein 1 chr11 GO:0048585 Not Cancer Driver No 35 0.118 271 33 0.122 0
UCMA UCMA Q8WVF2 Unique cartilage matrix-associated protein chr10 GO:0048585 Not Cancer Driver No 33 0.239 96 22 0.229 0
UCN UCN P55089 Urocortin chr2 GO:0048585 Not Cancer Driver No 7 0.056 61 4 0.066 0
UCP2 UCP2 P55851 Mitochondrial uncoupling protein 2 chr11 GO:0048585 Not Cancer Driver No 31 0.1 11 3 0.273 0
UFD1 UFD1 Q92890 Ubiquitin recognition factor in ER-associated degradation protein 1 chr22 GO:0048585 Not Cancer Driver No 26 0.085 100 7 0.07 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 GO:0048585 Not Cancer Driver No 109 0.137 141 24 0.17 0
ULK3 ULK3 Q6PHR2 Serine/threonine-protein kinase ULK3 chr15 GO:0048585 Not Cancer Driver No 37 0.078 55 2 0.036 0
UNC5B UNC5B Q8IZJ1 Netrin receptor UNC5B chr10 GO:0048585 Not Cancer Driver No 155 0.164 117 20 0.171 0
USP14 USP14 P54578 Ubiquitin carboxyl-terminal hydrolase 14 chr18 GO:0048585 Not Cancer Driver No 59 0.119 86 6 0.07 0
USP15 USP15 Q9Y4E8 Ubiquitin carboxyl-terminal hydrolase 15 chr12 GO:0048585 Not Cancer Driver No 136 0.139 259 39 0.151 0
USP18 USP18 Q9UMW8 Ubl carboxyl-terminal hydrolase 18 chr22 GO:0048585 Not Cancer Driver No 34 0.091 29 8 0.276 0
USP25_ENST00000285679 USP25 Q9UHP3 Ubiquitin carboxyl-terminal hydrolase 25 chr21 GO:0048585 Not Cancer Driver No 135 0.128 354 55 0.155 0
USP47 USP47 Q96K76 Ubiquitin carboxyl-terminal hydrolase 47 chr11 GO:0048585 Not Cancer Driver No 137 0.1 425 39 0.092 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:0048585 Not Cancer Driver No 88 0.109 186 16 0.086 16
VEPH1 VEPH1 Q14D04 Ventricular zone-expressed PH domain-containing protein homolog 1 chr3 GO:0048585 Not Cancer Driver No 136 0.163 186 34 0.183 0
VGLL4_ENST00000273038 VGLL4 Q14135 Transcription cofactor vestigial-like protein 4 chr3 GO:0048585 Not Cancer Driver No 40 0.138 276 38 0.138 0
VHL VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 GO:0048585 Census, Compendium Yes 142 0.667 117 36 0.308 133
VNN1 VNN1 O95497 Pantetheinase chr6 GO:0048585 Not Cancer Driver No 88 0.172 20 5 0.25 0
VPS11 VPS11 Q9H270 Vacuolar protein sorting-associated protein 11 homolog chr11 GO:0048585 Not Cancer Driver No 96 0.102 118 6 0.051 1
VPS13C_ENST00000261517 VPS13C Q709C8 Intermembrane lipid transfer protein VPS13C chr15 GO:0048585 Not Cancer Driver No 446 0.119 433 51 0.118 1
VPS18 VPS18 Q9P253 Vacuolar protein sorting-associated protein 18 homolog chr15 GO:0048585 Not Cancer Driver No 96 0.099 86 7 0.081 0
VPS25 VPS25 Q9BRG1 Vacuolar protein-sorting-associated protein 25 chr17 GO:0048585 Not Cancer Driver No 16 0.091 10 0 0.0 0
VRK3_ENST00000594948 VRK3 Q8IV63 Inactive serine/threonine-protein kinase VRK3 chr19 GO:0048585 Not Cancer Driver No 65 0.137 180 18 0.1 0
VSIG4 VSIG4 Q9Y279 V-set and immunoglobulin domain-containing protein 4 chrX GO:0048585 Not Cancer Driver No 73 0.183 70 13 0.186 0
WFDC1_ENST00000568638 WFDC1 Q9HC57 WAP four-disulfide core domain protein 1 chr16 GO:0048585 Not Cancer Driver No 17 0.077 92 6 0.065 0
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 GO:0048585 Not Cancer Driver No 105 0.118 203 10 0.049 39
WNK2 WNK2 Q9Y3S1 Serine/threonine-protein kinase WNK2 chr9 GO:0048585 Census, Compendium Yes 223 0.097 1868 167 0.089 0
WNT11 WNT11 O96014 Protein Wnt-11 chr11 GO:0048585 Not Cancer Driver No 55 0.155 59 4 0.068 0
WNT3 WNT3 P56703 Proto-oncogene Wnt-3 chr17 GO:0048585 Not Cancer Driver No 56 0.158 34 7 0.206 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0048585 Not Cancer Driver No 77 0.219 37 5 0.135 0
WNT4 WNT4 P56705 Protein Wnt-4 chr1 GO:0048585 Not Cancer Driver No 30 0.085 39 4 0.103 4
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0048585 Not Cancer Driver No 66 0.174 0 0 0.0 2
WTIP WTIP A6NIX2 Wilms tumor protein 1-interacting protein chr19 GO:0048585 Not Cancer Driver No 32 0.074 217 2 0.009 0
WWC1_ENST00000265293 WWC1 Q8IX03 Protein KIBRA chr5 GO:0048585 Not Cancer Driver No 147 0.132 550 81 0.147 0
WWC2 WWC2 Q6AWC2 Protein WWC2 chr4 GO:0048585 Not Cancer Driver No 120 0.101 654 79 0.121 0
WWC3 WWC3 Q9ULE0 Protein WWC3 chrX GO:0048585 Not Cancer Driver No 214 0.196 638 114 0.179 0
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0048585 Not Cancer Driver No 19 0.073 169 9 0.053 0
XCL1 XCL1 P47992 Lymphotactin chr1 GO:0048585 Not Cancer Driver No 28 0.246 35 11 0.314 0
XDH XDH P47989 Xanthine dehydrogenase/oxidase chr2 GO:0048585 Not Cancer Driver No 279 0.209 134 24 0.179 1
XIAP_ENST00000434753 XIAP P98170 E3 ubiquitin-protein ligase XIAP chrX GO:0048585 Not Cancer Driver No 89 0.179 55 6 0.109 0
XRCC1 XRCC1 P18887 DNA repair protein XRCC1 chr19 GO:0048585 Not Cancer Driver No 85 0.134 426 53 0.124 1
YBX1 YBX1 P67809 Y-box-binding protein 1 chr1 GO:0048585 Not Cancer Driver No 41 0.127 312 41 0.131 0
YBX3 YBX3 P16989 Y-box-binding protein 3 chr12 GO:0048585 Not Cancer Driver No 49 0.132 359 47 0.131 0
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 GO:0048585 Not Cancer Driver No 65 0.12 62 10 0.161 0
YJU2 YJU2 Q9BW85 Splicing factor YJU2 chr19 GO:0048585 Not Cancer Driver No 29 0.09 233 13 0.056 0
YTHDF2_ENST00000542507 YTHDF2 Q9Y5A9 YTH domain-containing family protein 2 chr1 GO:0048585 Not Cancer Driver No 67 0.116 376 44 0.117 0
YTHDF3_ENST00000539294 YTHDF3 Q7Z739 YTH domain-containing family protein 3 chr8 GO:0048585 Not Cancer Driver No 74 0.126 409 51 0.125 0
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 GO:0048585 Not Cancer Driver No 22 0.089 109 4 0.037 0
ZBTB7A_ENST00000601588 ZBTB7A O95365 Zinc finger and BTB domain-containing protein 7A chr19 GO:0048585 Not Cancer Driver No 60 0.103 285 30 0.105 0
ZBTB7B_ENST00000368426 ZBTB7B O15156 Zinc finger and BTB domain-containing protein 7B chr1 GO:0048585 Compendium Yes 103 0.191 353 70 0.198 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0048585 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZC3HC1 ZC3HC1 Q86WB0 Zinc finger C3HC-type protein 1 chr7 GO:0048585 Not Cancer Driver No 70 0.139 250 34 0.136 0
ZFYVE28 ZFYVE28 Q9HCC9 Lateral signaling target protein 2 homolog chr4 GO:0048585 Not Cancer Driver No 132 0.149 420 67 0.16 0
ZGPAT ZGPAT Q8N5A5 Zinc finger CCCH-type with G patch domain-containing protein chr20 GO:0048585 Not Cancer Driver No 75 0.141 346 49 0.142 0
ZKSCAN3_ENST00000252211 ZKSCAN3 Q9BRR0 Zinc finger protein with KRAB and SCAN domains 3 chr6 GO:0048585 Not Cancer Driver No 70 0.13 267 30 0.112 0
ZMYND11 ZMYND11 Q15326 Zinc finger MYND domain-containing protein 11 chr10 GO:0048585 Not Cancer Driver No 71 0.118 184 26 0.141 0
ZNF366 ZNF366 Q8N895 Zinc finger protein 366 chr5 GO:0048585 Not Cancer Driver No 158 0.212 382 85 0.223 0
ZNF385A ZNF385A Q96PM9 Zinc finger protein 385A chr12 GO:0048585 Not Cancer Driver No 43 0.111 312 34 0.109 0
ZNF536 ZNF536 O15090 Zinc finger protein 536 chr19 GO:0048585 Not Cancer Driver No 596 0.458 991 445 0.449 0
ZNF653 ZNF653 Q96CK0 Zinc finger protein 653 chr19 GO:0048585 Not Cancer Driver No 78 0.127 371 45 0.121 0
ZNF675 ZNF675 Q8TD23 Zinc finger protein 675 chr19 GO:0048585 Not Cancer Driver No 114 0.201 91 19 0.209 0
ZNRF3 ZNRF3 Q9ULT6 E3 ubiquitin-protein ligase ZNRF3 chr22 GO:0048585 Census, Compendium Yes 94 0.1 510 51 0.1 0