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Total number of protein in "GO:0048584" GO term:  1273

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AAK1 AAK1 Q2M2I8 AP2-associated protein kinase 1 chr2 GO:0048584 Not Cancer Driver No 109 0.113 654 70 0.107 0
ABI3 ABI3 Q9P2A4 ABI gene family member 3 chr17 GO:0048584 Not Cancer Driver No 46 0.126 248 31 0.125 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0048584 Census, Compendium Yes 139 0.123 604 73 0.121 2
ABRA ABRA Q8N0Z2 Actin-binding Rho-activating protein chr8 GO:0048584 Not Cancer Driver No 108 0.283 285 86 0.302 0
AC136428.1 IGHV3OR16-17 S4R3C0 Immunoglobulin heavy variable 3/OR16-17 (non-functional) (Fragment) chr16 GO:0048584 Not Cancer Driver No 42 0.362 0 0 0.0 0
ACOD1 ACOD1 A6NK06 Cis-aconitate decarboxylase chr13 GO:0048584 Not Cancer Driver No 5 0.01 36 0 0.0 0
ACOX2 ACOX2 Q99424 Peroxisomal acyl-coenzyme A oxidase 2 chr3 GO:0048584 Not Cancer Driver No 79 0.116 35 9 0.257 1
ACPP_ENST00000336375 ACP3 P15309 Prostatic acid phosphatase chr3 GO:0048584 Not Cancer Driver No 81 0.21 24 5 0.208 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 GO:0048584 Not Cancer Driver No 112 0.299 43 5 0.116 5
ACTL6A ACTL6A O96019 Actin-like protein 6A chr3 GO:0048584 Not Cancer Driver No 61 0.142 74 15 0.203 0
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 GO:0048584 Not Cancer Driver No 51 0.129 6 2 0.333 0
ACVR1B_ENST00000257963 ACVR1B P36896 Activin receptor type-1B chr12 GO:0048584 Census Yes 114 0.226 0 0 0.0 0
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0048584 Census, Compendium Yes 78 0.153 21 8 0.381 8
ACVR2A_ENST00000404590 ACVR2A P27037 Activin receptor type-2A chr2 GO:0048584 Census, Compendium Yes 98 0.191 56 6 0.107 0
ACVR2B ACVR2B Q13705 Activin receptor type-2B chr3 GO:0048584 Not Cancer Driver No 83 0.162 70 14 0.2 2
ACVRL1 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0048584 Not Cancer Driver No 93 0.185 60 11 0.183 82
ADA ADA P00813 Adenosine deaminase chr20 GO:0048584 Not Cancer Driver No 50 0.138 44 9 0.205 27
ADAM10 ADAM10 O14672 Disintegrin and metalloproteinase domain-containing protein 10 chr15 GO:0048584 Not Cancer Driver No 88 0.118 156 20 0.128 4
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0048584 Not Cancer Driver No 80 0.097 182 17 0.093 0
ADAM8 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:0048584 Not Cancer Driver No 82 0.1 230 13 0.057 0
ADAMTS3 ADAMTS3 O15072 A disintegrin and metalloproteinase with thrombospondin motifs 3 chr4 GO:0048584 Not Cancer Driver No 253 0.21 295 78 0.264 2
ADCYAP1R1_ENST00000304166 ADCYAP1R1 P41586 Pituitary adenylate cyclase-activating polypeptide type I receptor chr7 GO:0048584 Not Cancer Driver No 127 0.271 0 0 0.0 0
ADGRG1 ADGRG1 Q9Y653 Adhesion G-protein coupled receptor G1 chr16 GO:0048584 Not Cancer Driver No 64 0.092 67 4 0.06 9
ADGRV1_ENST00000645211 ADGRV1 Q8WXG9 Adhesion G-protein coupled receptor V1 chr5 GO:0048584 Not Cancer Driver No 1124 0.178 496 77 0.155 2
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0048584 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADIPOR1 ADIPOR1 Q96A54 Adiponectin receptor protein 1 chr1 GO:0048584 Not Cancer Driver No 63 0.168 69 10 0.145 0
ADORA1 ADORA1 P30542 Adenosine receptor A1 chr1 GO:0048584 Not Cancer Driver No 64 0.196 12 4 0.333 0
ADORA2B ADORA2B P29275 Adenosine receptor A2b chr17 GO:0048584 Not Cancer Driver No 23 0.069 0 0 0.0 0
ADRA1A_ENST00000380573 ADRA1A P35348 Alpha-1A adrenergic receptor chr8 GO:0048584 Not Cancer Driver No 130 0.279 40 8 0.2 0
ADRA2A ADRA2A P08913 Alpha-2A adrenergic receptor chr10 GO:0048584 Not Cancer Driver No 67 0.144 161 10 0.062 0
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 GO:0048584 Not Cancer Driver No 52 0.126 35 4 0.114 0
AFAP1L2 AFAP1L2 Q8N4X5 Actin filament-associated protein 1-like 2 chr10 GO:0048584 Not Cancer Driver No 86 0.105 558 59 0.106 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0048584 Not Cancer Driver No 31 0.077 297 21 0.071 0
AGPAT1 AGPAT1 Q99943 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha chr6 GO:0048584 Not Cancer Driver No 36 0.127 38 5 0.132 0
AGPAT2_ENST00000538402 AGPAT2 O15120 1-acyl-sn-glycerol-3-phosphate acyltransferase beta chr9 GO:0048584 Not Cancer Driver No 25 0.09 23 2 0.087 3
AGR2 AGR2 O95994 Anterior gradient protein 2 homolog chr7 GO:0048584 Not Cancer Driver No 23 0.131 20 2 0.1 0
AGT AGT P01019 Angiotensinogen chr1 GO:0048584 Not Cancer Driver No 85 0.179 33 10 0.303 1
AIF1 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0048584 Not Cancer Driver No 14 0.095 61 6 0.098 0
AKAP12 AKAP12 Q02952 A-kinase anchor protein 12 chr6 GO:0048584 Not Cancer Driver No 215 0.121 1770 214 0.121 0
AKAP13_ENST00000394518 AKAP13 Q12802 A-kinase anchor protein 13 chr15 GO:0048584 Not Cancer Driver No 359 0.128 2091 258 0.123 0
AKAP6 AKAP6 Q13023 A-kinase anchor protein 6 chr14 GO:0048584 Not Cancer Driver No 383 0.165 1456 240 0.165 0
AKIRIN1 AKIRIN1 Q9H9L7 Akirin-1 chr1 GO:0048584 Not Cancer Driver No 11 0.057 125 9 0.072 0
ALKAL1 ALKAL1 Q6UXT8 ALK and LTK ligand 1 chr8 GO:0048584 Not Cancer Driver No 18 0.14 49 3 0.061 0
ALKAL2 ALKAL2 Q6UX46 ALK and LTK ligand 2 chr2 GO:0048584 Not Cancer Driver No 7 0.046 31 0 0.0 0
ALOX15B ALOX15B O15296 Polyunsaturated fatty acid lipoxygenase ALOX15B chr17 GO:0048584 Not Cancer Driver No 99 0.146 62 12 0.194 0
ALOX5AP_ENST00000380490 ALOX5AP P20292 Arachidonate 5-lipoxygenase-activating protein chr13 GO:0048584 Not Cancer Driver No 17 0.106 1 0 0.0 0
ALS2 ALS2 Q96Q42 Alsin chr2 GO:0048584 Not Cancer Driver No 194 0.117 353 36 0.102 0
ANGPT1 ANGPT1 Q15389 Angiopoietin-1 chr8 GO:0048584 Not Cancer Driver No 130 0.261 131 24 0.183 1
ANKRD1 ANKRD1 Q15327 Ankyrin repeat domain-containing protein 1 chr10 GO:0048584 Not Cancer Driver No 52 0.163 83 13 0.157 0
ANKRD17 ANKRD17 O75179 Ankyrin repeat domain-containing protein 17 chr4 GO:0048584 Not Cancer Driver No 312 0.12 1790 221 0.123 9
ANKRD6_ENST00000339746 ANKRD6 Q9Y2G4 Ankyrin repeat domain-containing protein 6 chr6 GO:0048584 Not Cancer Driver No 91 0.125 500 61 0.122 0
ANO6_ENST00000320560 ANO6 Q4KMQ2 Anoctamin-6 chr12 GO:0048584 Not Cancer Driver No 134 0.147 80 11 0.138 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0048584 Not Cancer Driver No 59 0.171 61 12 0.197 0
AP1G1_ENST00000569748 AP1G1 O43747 AP-1 complex subunit gamma-1 chr16 GO:0048584 Not Cancer Driver No 111 0.135 144 22 0.153 0
APCS APCS P02743 Serum amyloid P-component chr1 GO:0048584 Not Cancer Driver No 73 0.327 0 0 0.0 0
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 GO:0048584 Not Cancer Driver No 28 0.105 131 8 0.061 3
APOH APOH P02749 Beta-2-glycoprotein 1 chr17 GO:0048584 Not Cancer Driver No 67 0.194 0 0 0.0 0
APPL2_ENST00000258530 APPL2 Q8NEU8 DCC-interacting protein 13-beta chr12 GO:0048584 Not Cancer Driver No 70 0.105 149 14 0.094 0
AR AR P10275 Androgen receptor chrX GO:0048584 Census, Compendium Yes 196 0.213 443 88 0.199 169
AREG AREG P15514 Amphiregulin chr4 GO:0048584 Not Cancer Driver No 28 0.111 149 20 0.134 0
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:0048584 Not Cancer Driver No 41 0.127 83 12 0.145 9
ARG2 ARG2 P78540 Arginase-2, mitochondrial chr14 GO:0048584 Not Cancer Driver No 25 0.071 58 3 0.052 0
ARHGEF3_ENST00000296315 ARHGEF3 Q9NR81 Rho guanine nucleotide exchange factor 3 chr3 GO:0048584 Not Cancer Driver No 70 0.133 154 17 0.11 0
ARHGEF5 ARHGEF5 Q12774 Rho guanine nucleotide exchange factor 5 chr7 GO:0048584 Not Cancer Driver No 170 0.106 1141 127 0.111 0
ARID2 ARID2 Q68CP9 AT-rich interactive domain-containing protein 2 chr12 GO:0048584 Census, Compendium Yes 272 0.148 1143 141 0.123 0
ARID5A ARID5A Q03989 AT-rich interactive domain-containing protein 5A chr2 GO:0048584 Not Cancer Driver No 64 0.108 373 42 0.113 0
ARMC9 ARMC9 Q7Z3E5 LisH domain-containing protein ARMC9 chr2 GO:0048584 Not Cancer Driver No 86 0.105 253 21 0.083 0
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 GO:0048584 Census Yes 77 0.098 511 56 0.11 0
ARRB1 ARRB1 P49407 Beta-arrestin-1 chr11 GO:0048584 Not Cancer Driver No 49 0.117 154 13 0.084 0
ARTN_ENST00000372354 ARTN Q5T4W7 Artemin chr1 GO:0048584 Not Cancer Driver No 11 0.05 154 6 0.039 0
ASCL1 ASCL1 P50553 Achaete-scute homolog 1 chr12 GO:0048584 Not Cancer Driver No 33 0.14 182 24 0.132 0
ASXL1_ENST00000613218 ASXL1 Q8IXJ9 Polycomb group protein ASXL1 chr20 GO:0048584 Census, Compendium Yes 205 0.133 1300 174 0.134 0
ASXL2_ENST00000435504 ASXL2 Q76L83 Putative Polycomb group protein ASXL2 chr2 GO:0048584 Census, Compendium Yes 209 0.146 1275 174 0.136 0
ATAD5 ATAD5 Q96QE3 ATPase family AAA domain-containing protein 5 chr17 GO:0048584 Not Cancer Driver No 200 0.108 1075 112 0.104 0
ATF3_ENST00000366987 ATF3 P18847 Cyclic AMP-dependent transcription factor ATF-3 chr1 GO:0048584 Not Cancer Driver No 23 0.127 118 14 0.119 0
ATF6 ATF6 P18850 Cyclic AMP-dependent transcription factor ATF-6 alpha chr1 GO:0048584 Not Cancer Driver No 88 0.131 468 59 0.126 2
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0048584 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX GO:0048584 Not Cancer Driver No 228 0.152 171 46 0.269 52
ATR ATR Q13535 Serine/threonine-protein kinase ATR chr3 GO:0048584 Census, Compendium Yes 338 0.128 106 14 0.132 1
ATXN3 ATXN3 P54252 Ataxin-3 chr14 GO:0048584 Not Cancer Driver No 46 0.127 181 24 0.133 0
AUTS2 AUTS2 Q8WXX7 Autism susceptibility gene 2 protein chr7 GO:0048584 Not Cancer Driver No 219 0.174 1218 213 0.175 0
AXIN1 AXIN1 O15169 Axin-1 chr16 GO:0048584 Census, Compendium Yes 120 0.139 619 88 0.142 4
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 GO:0048584 Not Cancer Driver No 168 0.188 341 64 0.188 0
AZGP1 AZGP1 P25311 Zinc-alpha-2-glycoprotein chr7 GO:0048584 Not Cancer Driver No 59 0.198 41 10 0.244 0
AZU1 AZU1 P20160 Azurocidin chr19 GO:0048584 Not Cancer Driver No 42 0.167 53 13 0.245 0
B2M B2M P61769 Beta-2-microglobulin chr15 GO:0048584 Census, Compendium Yes 34 0.286 5 1 0.2 2
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0048584 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 GO:0048584 Not Cancer Driver No 98 0.087 861 79 0.092 0
BAIAP2 BAIAP2 Q9UQB8 Brain-specific angiogenesis inhibitor 1-associated protein 2 chr17 GO:0048584 Not Cancer Driver No 85 0.154 330 52 0.158 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0048584 Not Cancer Driver No 38 0.18 58 9 0.155 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0048584 Census Yes 30 0.156 39 2 0.051 0
BBC3 BBC3 Q96PG8 Bcl-2-binding component 3, isoforms 3/4 chr19 GO:0048584 Not Cancer Driver No 20 0.077 253 20 0.079 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX GO:0048584 Not Cancer Driver No 37 0.15 104 14 0.135 0
BCAR3_ENST00000260502 BCAR3 O75815 Breast cancer anti-estrogen resistance protein 3 chr1 GO:0048584 Not Cancer Driver No 102 0.124 395 42 0.106 0
BCL10 BCL10 O95999 B-cell lymphoma/leukemia 10 chr1 GO:0048584 Census, Compendium Yes 36 0.155 151 25 0.166 0
BCL2L11 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:0048584 Not Cancer Driver No 42 0.212 130 17 0.131 0
BCLAF1 BCLAF1 Q9NYF8 Bcl-2-associated transcription factor 1 chr6 GO:0048584 Census, Compendium Yes 421 0.458 899 408 0.454 0
BDNF_ENST00000439476 BDNF P23560 Brain-derived neurotrophic factor chr11 GO:0048584 Not Cancer Driver No 47 0.19 79 19 0.241 1
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0048584 Not Cancer Driver No 45 0.1 190 19 0.1 0
BID_ENST00000551952 BID P55957 BH3-interacting domain death agonist chr22 GO:0048584 Not Cancer Driver No 23 0.118 74 9 0.122 0
BLK BLK P51451 Tyrosine-protein kinase Blk chr8 GO:0048584 Not Cancer Driver No 94 0.186 75 21 0.28 0
BMP10 BMP10 O95393 Bone morphogenetic protein 10 chr2 GO:0048584 Not Cancer Driver No 88 0.208 87 13 0.149 0
BMP15 BMP15 O95972 Bone morphogenetic protein 15 chrX GO:0048584 Not Cancer Driver No 91 0.232 81 15 0.185 13
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0048584 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP2K BMP2K Q9NSY1 BMP-2-inducible protein kinase chr4 GO:0048584 Not Cancer Driver No 124 0.107 827 89 0.108 0
BMP3 BMP3 P12645 Bone morphogenetic protein 3 chr4 GO:0048584 Not Cancer Driver No 120 0.254 147 48 0.327 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0048584 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMP5 BMP5 P22003 Bone morphogenetic protein 5 chr6 GO:0048584 Census Yes 163 0.359 112 62 0.554 0
BMP6 BMP6 P22004 Bone morphogenetic protein 6 chr6 GO:0048584 Not Cancer Driver No 95 0.185 226 51 0.226 0
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0048584 Not Cancer Driver No 91 0.211 69 18 0.261 0
BMP8A BMP8A Q7Z5Y6 Bone morphogenetic protein 8A chr1 GO:0048584 Not Cancer Driver No 26 0.065 93 2 0.022 0
BMP8B BMP8B P34820 Bone morphogenetic protein 8B chr1 GO:0048584 Not Cancer Driver No 21 0.052 90 3 0.033 0
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0048584 Census, Compendium Yes 66 0.124 21 0 0.0 8
BMPR1B_ENST00000394931 BMPR1B O00238 Bone morphogenetic protein receptor type-1B chr4 GO:0048584 Not Cancer Driver No 84 0.167 64 12 0.188 5
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0048584 Compendium Yes 141 0.136 601 70 0.116 19
BOK BOK Q9UMX3 Bcl-2-related ovarian killer protein chr2 GO:0048584 Not Cancer Driver No 7 0.033 0 0 0.0 0
BRD8 BRD8 Q9H0E9 Bromodomain-containing protein 8 chr5 GO:0048584 Not Cancer Driver No 189 0.153 934 147 0.157 0
BTC BTC P35070 Probetacellulin chr4 GO:0048584 Not Cancer Driver No 29 0.163 12 5 0.417 0
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX GO:0048584 Census, Compendium Yes 147 0.223 114 27 0.237 110
C10orf71 CEFIP Q711Q0 Cardiac-enriched FHL2-interacting protein chr10 GO:0048584 Not Cancer Driver No 229 0.16 1356 218 0.161 0
C12orf49 SPRING1 Q9H741 SREBP regulating gene protein chr12 GO:0048584 Not Cancer Driver No 26 0.127 0 0 0.0 0
C17orf99 C17orf99 Q6UX52 Protein IL-40 chr17 GO:0048584 Not Cancer Driver No 16 0.06 84 3 0.036 0
C1QA C1QA P02745 Complement C1q subcomponent subunit A chr1 GO:0048584 Not Cancer Driver No 41 0.167 124 16 0.129 0
C1QB C1QB P02746 Complement C1q subcomponent subunit B chr1 GO:0048584 Not Cancer Driver No 46 0.182 133 31 0.233 1
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 GO:0048584 Not Cancer Driver No 14 0.05 103 6 0.058 2
C1QC C1QC P02747 Complement C1q subcomponent subunit C chr1 GO:0048584 Not Cancer Driver No 46 0.188 134 26 0.194 1
C1QTNF12 C1QTNF12 Q5T7M4 Adipolin chr1 GO:0048584 Not Cancer Driver No 13 0.043 105 5 0.048 0
C1QTNF4 C1QTNF4 Q9BXJ3 Complement C1q tumor necrosis factor-related protein 4 chr11 GO:0048584 Not Cancer Driver No 25 0.076 91 4 0.044 0
C1R C1R P00736 Complement C1r subcomponent chr12 GO:0048584 Not Cancer Driver No 88 0.125 51 6 0.118 6
C1RL C1RL Q9NZP8 Complement C1r subcomponent-like protein chr12 GO:0048584 Not Cancer Driver No 60 0.123 146 22 0.151 0
C1S C1S P09871 Complement C1s subcomponent chr12 GO:0048584 Not Cancer Driver No 128 0.186 97 21 0.216 1
C2 C2 P06681 Complement C2 chr6 GO:0048584 Not Cancer Driver No 120 0.16 120 17 0.142 3
C20orf27_ENST00000379772 C20orf27 Q9GZN8 UPF0687 protein C20orf27 chr20 GO:0048584 Not Cancer Driver No 27 0.155 31 4 0.129 0
C2CD4A C2CD4A Q8NCU7 C2 calcium-dependent domain-containing protein 4A chr15 GO:0048584 Not Cancer Driver No 13 0.035 223 4 0.018 0
C2CD4B C2CD4B A6NLJ0 C2 calcium-dependent domain-containing protein 4B chr15 GO:0048584 Not Cancer Driver No 5 0.014 191 0 0.0 0
C3 C3 P01024 Complement C3 chr19 GO:0048584 Not Cancer Driver No 337 0.203 287 50 0.174 12
C3AR1 C3AR1 Q16581 C3a anaphylatoxin chemotactic receptor chr12 GO:0048584 Not Cancer Driver No 88 0.183 72 16 0.222 0
C4A C4A P0C0L4 Complement C4-A chr6 GO:0048584 Not Cancer Driver No 43 0.025 309 6 0.019 0
C4BPA C4BPA P04003 C4b-binding protein alpha chain chr1 GO:0048584 Not Cancer Driver No 109 0.183 40 10 0.25 0
C4BPB C4BPB P20851 C4b-binding protein beta chain chr1 GO:0048584 Not Cancer Driver No 40 0.159 0 0 0.0 0
C5 C5 P01031 Complement C5 chr9 GO:0048584 Not Cancer Driver No 192 0.115 84 9 0.107 0
C5AR1 C5AR1 P21730 C5a anaphylatoxin chemotactic receptor 1 chr19 GO:0048584 Not Cancer Driver No 71 0.203 0 0 0.0 0
C5AR2_ENST00000600626 C5AR2 Q9P296 C5a anaphylatoxin chemotactic receptor 2 chr19 GO:0048584 Not Cancer Driver No 60 0.178 11 3 0.273 0
C6 C6 P13671 Complement component C6 chr5 GO:0048584 Not Cancer Driver No 346 0.37 121 47 0.388 0
C7 C7 P10643 Complement component C7 chr5 GO:0048584 Not Cancer Driver No 291 0.345 89 37 0.416 5
C8A C8A P07357 Complement component C8 alpha chain chr1 GO:0048584 Not Cancer Driver No 176 0.301 25 9 0.36 0
C8B C8B P07358 Complement component C8 beta chain chr1 GO:0048584 Not Cancer Driver No 186 0.315 29 11 0.379 0
C8G C8G P07360 Complement component C8 gamma chain chr9 GO:0048584 Not Cancer Driver No 10 0.05 26 2 0.077 0
C9 C9 P02748 Complement component C9 chr5 GO:0048584 Not Cancer Driver No 156 0.279 40 8 0.2 2
CADM1_ENST00000452722 CADM1 Q9BY67 Cell adhesion molecule 1 chr11 GO:0048584 Not Cancer Driver No 106 0.24 103 28 0.272 0
CALCR_ENST00000394441 CALCR P30988 Calcitonin receptor chr7 GO:0048584 Not Cancer Driver No 162 0.342 29 9 0.31 0
CALR CALR P27797 Calreticulin chr19 GO:0048584 Census Yes 45 0.108 245 31 0.127 0
CAMK1D CAMK1D Q8IU85 Calcium/calmodulin-dependent protein kinase type 1D chr10 GO:0048584 Not Cancer Driver No 90 0.234 42 14 0.333 0
CAMTA1 CAMTA1 Q9Y6Y1 Calmodulin-binding transcription activator 1 chr1 GO:0048584 Census, Compendium Yes 300 0.179 883 152 0.172 0
CARD11 CARD11 Q9BXL7 Caspase recruitment domain-containing protein 11 chr7 GO:0048584 Census, Compendium Yes 303 0.263 530 140 0.264 5
CARD9 CARD9 Q9H257 Caspase recruitment domain-containing protein 9 chr9 GO:0048584 Not Cancer Driver No 72 0.134 225 35 0.156 11
CASP1 CASP1 P29466 Caspase-1 chr11 GO:0048584 Not Cancer Driver No 79 0.196 87 18 0.207 0
CASP4 CASP4 P49662 Caspase-4 chr11 GO:0048584 Not Cancer Driver No 56 0.149 102 14 0.137 0
CASR_ENST00000638421 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0048584 Not Cancer Driver No 304 0.282 189 60 0.317 108
CAT CAT P04040 Catalase chr11 GO:0048584 Not Cancer Driver No 70 0.133 176 18 0.102 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0048584 Not Cancer Driver No 30 0.169 2 0 0.0 0
CAV2 CAV2 P51636 Caveolin-2 chr7 GO:0048584 Not Cancer Driver No 20 0.123 5 2 0.4 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0048584 Census, Compendium Yes 115 0.127 512 56 0.109 4
CCAR2 CCAR2 Q8N163 Cell cycle and apoptosis regulator protein 2 chr8 GO:0048584 Not Cancer Driver No 102 0.111 528 62 0.117 0
CCBE1 CCBE1 Q6UXH8 Collagen and calcium-binding EGF domain-containing protein 1 chr18 GO:0048584 Not Cancer Driver No 92 0.227 227 58 0.256 5
CCDC88A_ENST00000642200 CCDC88A Q3V6T2 Girdin chr2 GO:0048584 Not Cancer Driver No 226 0.121 1481 173 0.117 0
CCL1 CCL1 P22362 C-C motif chemokine 1 chr17 GO:0048584 Not Cancer Driver No 27 0.281 0 0 0.0 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0048584 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0048584 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCL27 CCL27 Q9Y4X3 C-C motif chemokine 27 chr9 GO:0048584 Not Cancer Driver No 15 0.134 0 0 0.0 0
CCL7 CCL7 P80098 C-C motif chemokine 7 chr17 GO:0048584 Not Cancer Driver No 30 0.303 13 3 0.231 0
CCN1 CCN1 O00622 CCN family member 1 chr1 GO:0048584 Not Cancer Driver No 33 0.087 12 0 0.0 0
CCN3 CCN3 P48745 CCN family member 3 chr8 GO:0048584 Not Cancer Driver No 66 0.185 19 1 0.053 0
CCR1 CCR1 P32246 C-C chemokine receptor type 1 chr3 GO:0048584 Not Cancer Driver No 69 0.194 14 5 0.357 0
CCR2_ENST00000400888 CCR2 P41597 C-C chemokine receptor type 2 chr3 GO:0048584 Not Cancer Driver No 81 0.217 23 1 0.043 0
CCR4 CCR4 P51679 C-C chemokine receptor type 4 chr3 GO:0048584 Census Yes 45 0.125 0 0 0.0 0
CCR6_ENST00000349984 CCR6 P51684 C-C chemokine receptor type 6 chr6 GO:0048584 Not Cancer Driver No 56 0.15 13 2 0.154 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0048584 Census, Compendium Yes 50 0.132 0 0 0.0 0
CD160_ENST00000369288 CD160 O95971 CD160 antigen chr1 GO:0048584 Not Cancer Driver No 20 0.11 2 0 0.0 0
CD177 CD177 Q8N6Q3 CD177 antigen chr19 GO:0048584 Not Cancer Driver No 71 0.162 79 26 0.329 0
CD180 CD180 Q99467 CD180 antigen chr5 GO:0048584 Not Cancer Driver No 105 0.159 0 0 0.0 0
CD1A CD1A P06126 T-cell surface glycoprotein CD1a chr1 GO:0048584 Not Cancer Driver No 105 0.321 18 6 0.333 0
CD1B CD1B P29016 T-cell surface glycoprotein CD1b chr1 GO:0048584 Not Cancer Driver No 97 0.291 7 0 0.0 0
CD1C CD1C P29017 T-cell surface glycoprotein CD1c chr1 GO:0048584 Not Cancer Driver No 127 0.381 1 0 0.0 0
CD1D CD1D P15813 Antigen-presenting glycoprotein CD1d chr1 GO:0048584 Not Cancer Driver No 93 0.278 19 7 0.368 0
CD1E CD1E P15812 T-cell surface glycoprotein CD1e, membrane-associated chr1 GO:0048584 Not Cancer Driver No 158 0.407 21 11 0.524 0
CD226_ENST00000582621 CD226 Q15762 CD226 antigen chr18 GO:0048584 Not Cancer Driver No 79 0.235 47 11 0.234 0
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 GO:0048584 Census Yes 29 0.1 54 9 0.167 0
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:0048584 Census Yes 42 0.191 18 10 0.556 0
CD300LF_ENST00000326165 CD300LF Q8TDQ1 CMRF35-like molecule 1 chr17 GO:0048584 Not Cancer Driver No 36 0.124 88 11 0.125 0
CD36_ENST00000309881 CD36 P16671 Platelet glycoprotein 4 chr7 GO:0048584 Not Cancer Driver No 75 0.159 12 3 0.25 3
CD3E CD3E P07766 T-cell surface glycoprotein CD3 epsilon chain chr11 GO:0048584 Not Cancer Driver No 28 0.135 72 12 0.167 0
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 GO:0048584 Not Cancer Driver No 69 0.151 56 11 0.196 0
CD40 CD40 P25942 Tumor necrosis factor receptor superfamily member 5 chr20 GO:0048584 Not Cancer Driver No 39 0.141 56 6 0.107 2
CD46_ENST00000358170 CD46 P15529 Membrane cofactor protein chr1 GO:0048584 Not Cancer Driver No 53 0.135 52 4 0.077 5
CD55_ENST00000367064 CD55 P08174 Complement decay-accelerating factor chr1 GO:0048584 Not Cancer Driver No 45 0.118 128 13 0.102 1
CD63_ENST00000552692 CD63 P08962 CD63 antigen chr12 GO:0048584 Not Cancer Driver No 27 0.113 0 0 0.0 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0048584 Census Yes 31 0.105 185 20 0.108 0
CD80_ENST00000478182 CD80 P33681 T-lymphocyte activation antigen CD80 chr3 GO:0048584 Not Cancer Driver No 50 0.174 26 5 0.192 0
CD81 CD81 P60033 CD81 antigen chr11 GO:0048584 Not Cancer Driver No 28 0.119 0 0 0.0 0
CD86 CD86 P42081 T-lymphocyte activation antigen CD86 chr3 GO:0048584 Not Cancer Driver No 90 0.274 56 18 0.321 0
CDH13_ENST00000567109 CDH13 P55290 Cadherin-13 chr16 GO:0048584 Not Cancer Driver No 168 0.236 235 59 0.251 0
CDH3 CDH3 P22223 Cadherin-3 chr16 GO:0048584 Not Cancer Driver No 87 0.105 488 52 0.107 2
CDH5 CDH5 P33151 Cadherin-5 chr16 GO:0048584 Not Cancer Driver No 144 0.184 305 55 0.18 0
CDK5RAP3_ENST00000338399 CDK5RAP3 Q96JB5 CDK5 regulatory subunit-associated protein 3 chr17 GO:0048584 Not Cancer Driver No 50 0.099 99 20 0.202 0
CDKN1C CDKN1C P49918 Cyclin-dependent kinase inhibitor 1C chr11 GO:0048584 Not Cancer Driver No 2 0.006 256 1 0.004 7
CDKN2B CDKN2B P42772 Cyclin-dependent kinase 4 inhibitor B chr9 GO:0048584 Not Cancer Driver No 15 0.109 67 3 0.045 0
CFB CFB P00751 Complement factor B chr6 GO:0048584 Not Cancer Driver No 75 0.098 112 20 0.179 7
CFD_ENST00000327726 CFD P00746 Complement factor D chr19 GO:0048584 Not Cancer Driver No 6 0.024 69 3 0.043 2
CFH CFH P08603 Complement factor H chr1 GO:0048584 Not Cancer Driver No 355 0.288 89 28 0.315 42
CFHR5 CFHR5 Q9BXR6 Complement factor H-related protein 5 chr1 GO:0048584 Not Cancer Driver No 162 0.285 40 9 0.225 0
CFI_ENST00000394634 CFI P05156 Complement factor I chr4 GO:0048584 Not Cancer Driver No 97 0.166 4 0 0.0 13
CFP CFP P27918 Properdin chrX GO:0048584 Not Cancer Driver No 60 0.128 48 7 0.146 6
CGAS CGAS Q8N884 Cyclic GMP-AMP synthase chr6 GO:0048584 Not Cancer Driver No 50 0.096 173 7 0.04 0
CHD5 CHD5 Q8TDI0 Chromodomain-helicase-DNA-binding protein 5 chr1 GO:0048584 Not Cancer Driver No 365 0.187 931 183 0.197 0
CHERP CHERP Q8IWX8 Calcium homeostasis endoplasmic reticulum protein chr19 GO:0048584 Not Cancer Driver No 109 0.119 707 79 0.112 0
CHGA CHGA P10645 Chromogranin-A chr14 GO:0048584 Not Cancer Driver No 46 0.101 421 44 0.105 0
CHP2 CHP2 O43745 Calcineurin B homologous protein 2 chr16 GO:0048584 Not Cancer Driver No 43 0.219 65 16 0.246 0
CHRNA7_ENST00000306901 CHRNA7 P36544 Neuronal acetylcholine receptor subunit alpha-7 chr15 GO:0048584 Not Cancer Driver No 71 0.141 18 4 0.222 0
CHSY1 CHSY1 Q86X52 Chondroitin sulfate synthase 1 chr15 GO:0048584 Not Cancer Driver No 95 0.118 137 10 0.073 1
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0048584 Not Cancer Driver No 24 0.126 6 1 0.167 0
CITED1_ENST00000246139 CITED1 Q99966 Cbp/p300-interacting transactivator 1 chrX GO:0048584 Not Cancer Driver No 24 0.124 166 21 0.127 0
CITED2_ENST00000367651 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:0048584 Not Cancer Driver No 23 0.085 230 18 0.078 0
CLCF1 CLCF1 Q9UBD9 Cardiotrophin-like cytokine factor 1 chr11 GO:0048584 Not Cancer Driver No 22 0.098 42 4 0.095 1
CLEC16A CLEC16A Q2KHT3 Protein CLEC16A chr16 GO:0048584 Not Cancer Driver No 149 0.142 374 53 0.142 0
CLEC6A CLEC6A Q6EIG7 C-type lectin domain family 6 member A chr12 GO:0048584 Not Cancer Driver No 41 0.196 7 0 0.0 0
CLEC7A CLEC7A Q9BXN2 C-type lectin domain family 7 member A chr12 GO:0048584 Not Cancer Driver No 43 0.174 46 2 0.043 0
CLNK CLNK Q7Z7G1 Cytokine-dependent hematopoietic cell linker chr4 GO:0048584 Not Cancer Driver No 85 0.199 320 73 0.228 0
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0048584 Not Cancer Driver No 69 0.154 156 27 0.173 0
CMKLR1 CMKLR1 Q99788 Chemerin-like receptor 1 chr12 GO:0048584 Not Cancer Driver No 107 0.287 24 13 0.542 0
CMTM3_ENST00000567572 CMTM3 Q96MX0 CKLF-like MARVEL transmembrane domain-containing protein 3 chr16 GO:0048584 Not Cancer Driver No 16 0.088 39 1 0.026 0
CNOT9_ENST00000273064 CNOT9 Q92600 CCR4-NOT transcription complex subunit 9 chr2 GO:0048584 Compendium Yes 42 0.14 30 0 0.0 0
CNR1_ENST00000549890 CNR1 P21554 Cannabinoid receptor 1 chr6 GO:0048584 Not Cancer Driver No 129 0.273 9 1 0.111 0
CNTF CNTF P26441 Ciliary neurotrophic factor chr11 GO:0048584 Not Cancer Driver No 41 0.205 34 5 0.147 0
CNTN2 CNTN2 Q02246 Contactin-2 chr1 GO:0048584 Not Cancer Driver No 155 0.149 370 61 0.165 0
CNTN6_ENST00000350110 CNTN6 Q9UQ52 Contactin-6 chr3 GO:0048584 Not Cancer Driver No 330 0.321 173 59 0.341 0
COL3A1 COL3A1 P02461 Collagen alpha-1(III) chain chr2 GO:0048584 Census Yes 402 0.274 1182 337 0.285 103
COLEC10 COLEC10 Q9Y6Z7 Collectin-10 chr8 GO:0048584 Not Cancer Driver No 58 0.209 95 23 0.242 1
COLEC11_ENST00000349077 COLEC11 Q9BWP8 Collectin-11 chr2 GO:0048584 Not Cancer Driver No 72 0.266 158 40 0.253 2
CPB2_ENST00000645658 CPB2 Q96IY4 Carboxypeptidase B2 chr13 GO:0048584 Not Cancer Driver No 59 0.139 2 0 0.0 0
CPNE1_ENST00000352393 CPNE1 Q99829 Copine-1 chr20 GO:0048584 Not Cancer Driver No 74 0.138 80 7 0.087 0
CR1_ENST00000367053 CR1 P17927 Complement receptor type 1 chr1 GO:0048584 Compendium Yes 383 0.188 151 42 0.278 0
CR2_ENST00000367058 CR2 P20023 Complement receptor type 2 chr1 GO:0048584 Not Cancer Driver No 273 0.264 85 28 0.329 0
CRB2 CRB2 Q5IJ48 Protein crumbs homolog 2 chr9 GO:0048584 Not Cancer Driver No 155 0.121 72 0 0.0 5
CREB3 CREB3 O43889 Cyclic AMP-responsive element-binding protein 3 chr9 GO:0048584 Not Cancer Driver No 33 0.089 168 11 0.065 0
CREB3L3 CREB3L3 Q68CJ9 Cyclic AMP-responsive element-binding protein 3-like protein 3 chr19 GO:0048584 Not Cancer Driver No 96 0.208 338 67 0.198 1
CREBBP CREBBP Q92793 CREB-binding protein chr16 GO:0048584 Census, Compendium Yes 412 0.169 1796 247 0.138 33
CRP CRP P02741 C-reactive protein chr1 GO:0048584 Not Cancer Driver No 59 0.263 0 0 0.0 0
CRTAM CRTAM O95727 Cytotoxic and regulatory T-cell molecule chr11 GO:0048584 Not Cancer Driver No 64 0.163 135 14 0.104 0
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0048584 Census Yes 133 0.137 124 17 0.137 20
CSF1_ENST00000369802 CSF1 P09603 Macrophage colony-stimulating factor 1 chr1 GO:0048584 Not Cancer Driver No 69 0.125 339 46 0.136 0
CSF3 CSF3 P09919 Granulocyte colony-stimulating factor chr17 GO:0048584 Not Cancer Driver No 20 0.097 7 0 0.0 0
CSNK1D CSNK1D P48730 Casein kinase I isoform delta chr17 GO:0048584 Not Cancer Driver No 59 0.142 132 16 0.121 2
CSNK1E CSNK1E P49674 Casein kinase I isoform epsilon chr22 GO:0048584 Not Cancer Driver No 62 0.149 133 18 0.135 0
CSNK2B_ENST00000375866 CSNK2B P67870 Casein kinase II subunit beta chr6 GO:0048584 Not Cancer Driver No 20 0.093 19 0 0.0 4
CTBP2_ENST00000494626 CTBP2 P56545 C-terminal-binding protein 2 chr10 GO:0048584 Not Cancer Driver No 48 0.108 94 4 0.043 0
CTNNA1 CTNNA1 P35221 Catenin alpha-1 chr5 GO:0048584 Census Yes 126 0.139 268 35 0.131 4
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0048584 Census, Compendium Yes 415 0.531 288 301 1.045 14
CTNS_ENST00000046640 CTNS O60931 Cystinosin chr17 GO:0048584 Not Cancer Driver No 34 0.093 0 0 0.0 31
CTSC CTSC P53634 Dipeptidyl peptidase 1 chr11 GO:0048584 Not Cancer Driver No 64 0.138 19 5 0.263 29
CUX2 CUX2 O14529 Homeobox protein cut-like 2 chr12 GO:0048584 Not Cancer Driver No 277 0.186 1201 212 0.177 1
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0048584 Not Cancer Driver No 80 0.225 0 0 0.0 0
CXCL10 CXCL10 P02778 C-X-C motif chemokine 10 chr4 GO:0048584 Not Cancer Driver No 19 0.194 12 4 0.333 0
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:0048584 Not Cancer Driver No 16 0.172 0 0 0.0 0
CXCL13 CXCL13 O43927 C-X-C motif chemokine 13 chr4 GO:0048584 Not Cancer Driver No 11 0.101 0 0 0.0 0
CXCL17 CXCL17 Q6UXB2 C-X-C motif chemokine 17 chr19 GO:0048584 Not Cancer Driver No 8 0.067 44 6 0.136 0
CXCL8 CXCL8 P10145 Interleukin-8 chr4 GO:0048584 Not Cancer Driver No 17 0.172 0 0 0.0 0
CXCR4_ENST00000241393 CXCR4 P61073 C-X-C chemokine receptor type 4 chr2 GO:0048584 Census, Compendium Yes 62 0.176 5 1 0.2 0
CXorf21 TASL Q9HAI6 TLR adapter interacting with SLC15A4 on the lysosome chrX GO:0048584 Not Cancer Driver No 73 0.243 66 21 0.318 0
CYBA CYBA P13498 Cytochrome b-245 light chain chr16 GO:0048584 Not Cancer Driver No 26 0.133 66 2 0.03 12
CYFIP1_ENST00000610365 CYFIP1 Q7L576 Cytoplasmic FMR1-interacting protein 1 chr15 GO:0048584 Not Cancer Driver No 46 0.037 96 0 0.0 0
CYFIP2 CYFIP2 Q96F07 Cytoplasmic FMR1-interacting protein 2 chr5 GO:0048584 Not Cancer Driver No 211 0.165 86 11 0.128 3
CYP27B1 CYP27B1 O15528 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial chr12 GO:0048584 Not Cancer Driver No 71 0.14 79 13 0.165 18
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0048584 Not Cancer Driver No 144 0.187 680 125 0.184 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0048584 Not Cancer Driver No 131 0.11 681 68 0.1 0
DAPK2 DAPK2 Q9UIK4 Death-associated protein kinase 2 chr15 GO:0048584 Not Cancer Driver No 55 0.149 53 9 0.17 0
DCDC2 DCDC2 Q9UHG0 Doublecortin domain-containing protein 2 chr6 GO:0048584 Not Cancer Driver No 72 0.151 264 41 0.155 2
DCN DCN P07585 Decorin chr12 GO:0048584 Not Cancer Driver No 96 0.267 81 26 0.321 0
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 GO:0048584 Census Yes 29 0.172 160 27 0.169 0
DDX11 DDX11 Q96FC9 ATP-dependent DNA helicase DDX11 chr12 GO:0048584 Not Cancer Driver No 154 0.159 280 55 0.196 1
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:0048584 Census, Compendium Yes 133 0.201 301 47 0.156 18
DDX5 DDX5 P17844 Probable ATP-dependent RNA helicase DDX5 chr17 GO:0048584 Census Yes 74 0.121 225 23 0.102 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 GO:0048584 Not Cancer Driver No 118 0.128 61 10 0.164 2
DDX60 DDX60 Q8IY21 Probable ATP-dependent RNA helicase DDX60 chr4 GO:0048584 Not Cancer Driver No 224 0.131 131 12 0.092 0
DEFB124 DEFB124 Q8NES8 Beta-defensin 124 chr20 GO:0048584 Not Cancer Driver No 9 0.127 3 0 0.0 0
DENND1B DENND1B Q6P3S1 DENN domain-containing protein 1B chr1 GO:0048584 Not Cancer Driver No 69 0.089 299 19 0.064 0
DGKD DGKD Q16760 Diacylglycerol kinase delta chr2 GO:0048584 Not Cancer Driver No 160 0.132 441 60 0.136 0
DHX58 DHX58 Q96C10 ATP-dependent RNA helicase DHX58 chr17 GO:0048584 Not Cancer Driver No 62 0.091 84 8 0.095 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0048584 Compendium Yes 182 0.143 331 42 0.127 0
DKK1 DKK1 O94907 Dickkopf-related protein 1 chr10 GO:0048584 Not Cancer Driver No 58 0.218 47 8 0.17 0
DLG4_ENST00000399506 DLG4 P78352 Disks large homolog 4 chr17 GO:0048584 Not Cancer Driver No 116 0.16 232 55 0.237 0
DLG5 DLG5 Q8TDM6 Disks large homolog 5 chr10 GO:0048584 Not Cancer Driver No 230 0.12 1119 135 0.121 0
DLL1 DLL1 O00548 Delta-like protein 1 chr6 GO:0048584 Not Cancer Driver No 115 0.159 145 24 0.166 1
DLL4 DLL4 Q9NR61 Delta-like protein 4 chr15 GO:0048584 Not Cancer Driver No 75 0.109 73 15 0.205 7
DMAP1_ENST00000315913 DMAP1 Q9NPF5 DNA methyltransferase 1-associated protein 1 chr1 GO:0048584 Not Cancer Driver No 49 0.105 269 28 0.104 0
DMTN_ENST00000358242 DMTN Q08495 Dematin chr8 GO:0048584 Not Cancer Driver No 53 0.131 348 46 0.132 0
DNM1L_ENST00000549701 DNM1L O00429 Dynamin-1-like protein chr12 GO:0048584 Not Cancer Driver No 67 0.091 212 23 0.108 7
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0048584 Not Cancer Driver No 127 0.287 124 45 0.363 0
DRD3_ENST00000460779 DRD3 P35462 D(3) dopamine receptor chr3 GO:0048584 Not Cancer Driver No 88 0.22 45 17 0.378 0
DSCAM DSCAM O60469 Down syndrome cell adhesion molecule chr21 GO:0048584 Not Cancer Driver No 652 0.324 603 201 0.333 0
DSTYK DSTYK Q6XUX3 Dual serine/threonine and tyrosine protein kinase chr1 GO:0048584 Not Cancer Driver No 112 0.121 112 4 0.036 2
DTX3L DTX3L Q8TDB6 E3 ubiquitin-protein ligase DTX3L chr3 GO:0048584 Not Cancer Driver No 86 0.116 260 24 0.092 0
DUSP19 DUSP19 Q8WTR2 Dual specificity protein phosphatase 19 chr2 GO:0048584 Not Cancer Driver No 34 0.157 15 5 0.333 0
DVL1 DVL1 O14640 Segment polarity protein dishevelled homolog DVL-1 chr1 GO:0048584 Not Cancer Driver No 73 0.105 434 38 0.088 0
DVL2 DVL2 O14641 Segment polarity protein dishevelled homolog DVL-2 chr17 GO:0048584 Not Cancer Driver No 96 0.13 514 64 0.125 0
DVL3 DVL3 Q92997 Segment polarity protein dishevelled homolog DVL-3 chr3 GO:0048584 Not Cancer Driver No 97 0.135 437 58 0.133 0
DYNC1LI1 DYNC1LI1 Q9Y6G9 Cytoplasmic dynein 1 light intermediate chain 1 chr3 GO:0048584 Not Cancer Driver No 46 0.088 208 20 0.096 0
DYNC2H1_ENST00000375735 DYNC2H1 Q8NCM8 Cytoplasmic dynein 2 heavy chain 1 chr11 GO:0048584 Not Cancer Driver No 510 0.118 282 15 0.053 34
ECHDC3 ECHDC3 Q96DC8 Enoyl-CoA hydratase domain-containing protein 3, mitochondrial chr10 GO:0048584 Not Cancer Driver No 34 0.112 45 1 0.022 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0048584 Not Cancer Driver No 37 0.175 97 20 0.206 3
EEF1E1 EEF1E1 O43324 Eukaryotic translation elongation factor 1 epsilon-1 chr6 GO:0048584 Not Cancer Driver No 27 0.155 11 1 0.091 0
EGF EGF P01133 Pro-epidermal growth factor chr4 GO:0048584 Not Cancer Driver No 184 0.152 191 25 0.131 1
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0048584 Census, Compendium Yes 444 0.367 223 35 0.157 1
EIF5A_ENST00000419711 EIF5A P63241 Eukaryotic translation initiation factor 5A-1 chr17 GO:0048584 Not Cancer Driver No 37 0.24 21 5 0.238 5
EMC10 EMC10 Q5UCC4 ER membrane protein complex subunit 10 chr19 GO:0048584 Not Cancer Driver No 25 0.095 109 15 0.138 0
EMILIN1 EMILIN1 Q9Y6C2 EMILIN-1 chr2 GO:0048584 Not Cancer Driver No 125 0.123 669 69 0.103 0
EMILIN2 EMILIN2 Q9BXX0 EMILIN-2 chr18 GO:0048584 Not Cancer Driver No 158 0.15 617 94 0.152 0
EMP2_ENST00000536829 EMP2 P54851 Epithelial membrane protein 2 chr16 GO:0048584 Not Cancer Driver No 24 0.144 0 0 0.0 2
ENDOG ENDOG Q14249 Endonuclease G, mitochondrial chr9 GO:0048584 Not Cancer Driver No 11 0.037 61 1 0.016 0
ENG ENG P17813 Endoglin chr9 GO:0048584 Not Cancer Driver No 60 0.091 114 15 0.132 32
ENHO ENHO Q6UWT2 Adropin chr9 GO:0048584 Not Cancer Driver No 12 0.158 32 5 0.156 0
ENPP4 ENPP4 Q9Y6X5 Bis(5'-adenosyl)-triphosphatase ENPP4 chr6 GO:0048584 Not Cancer Driver No 79 0.174 20 4 0.2 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0048584 Census, Compendium Yes 334 0.138 1790 196 0.109 1
EP400 EP400 Q96L91 E1A-binding protein p400 chr12 GO:0048584 Not Cancer Driver No 397 0.126 2064 234 0.113 0
EPC1 EPC1 Q9H2F5 Enhancer of polycomb homolog 1 chr10 GO:0048584 Not Cancer Driver No 104 0.124 515 68 0.132 0
EPC2 EPC2 Q52LR7 Enhancer of polycomb homolog 2 chr2 GO:0048584 Not Cancer Driver No 95 0.118 583 67 0.115 0
EPGN EPGN Q6UW88 Epigen chr4 GO:0048584 Not Cancer Driver No 16 0.104 0 0 0.0 0
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0048584 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPN2 EPN2 O95208 Epsin-2 chr17 GO:0048584 Not Cancer Driver No 73 0.114 543 61 0.112 0
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 GO:0048584 Census, Compendium Yes 298 0.222 396 70 0.177 3
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 GO:0048584 Census, Compendium Yes 428 0.327 323 116 0.359 2
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0048584 Not Cancer Driver No 211 0.141 829 117 0.141 9
EREG EREG O14944 Proepiregulin chr4 GO:0048584 Not Cancer Driver No 26 0.154 10 3 0.3 0
ERFE ERFE Q4G0M1 Erythroferrone chr2 GO:0048584 Not Cancer Driver No 4 0.011 179 0 0.0 0
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0048584 Not Cancer Driver No 125 0.128 250 28 0.112 0
ERN2 ERN2 Q76MJ5 Serine/threonine-protein kinase/endoribonuclease IRE2 chr16 GO:0048584 Not Cancer Driver No 192 0.207 213 45 0.211 0
ESM1 ESM1 Q9NQ30 Endothelial cell-specific molecule 1 chr5 GO:0048584 Not Cancer Driver No 44 0.239 37 11 0.297 0
ESRRA_ENST00000000442 ESRRA P11474 Steroid hormone receptor ERR1 chr11 GO:0048584 Compendium Yes 37 0.087 101 9 0.089 0
EVC EVC P57679 Ellis-van Creveld syndrome protein chr4 GO:0048584 Not Cancer Driver No 143 0.144 373 60 0.161 4
EXOSC3 EXOSC3 Q9NQT5 Exosome complex component RRP40 chr9 GO:0048584 Not Cancer Driver No 18 0.065 54 2 0.037 4
EXOSC6 EXOSC6 Q5RKV6 Exosome complex component MTR3 chr16 GO:0048584 Not Cancer Driver No 3 0.011 102 0 0.0 0
F11R F11R Q9Y624 Junctional adhesion molecule A chr1 GO:0048584 Not Cancer Driver No 47 0.157 72 15 0.208 0
F12 F12 P00748 Coagulation factor XII chr5 GO:0048584 Not Cancer Driver No 53 0.086 104 9 0.087 13
F2 F2 P00734 Prothrombin chr11 GO:0048584 Not Cancer Driver No 115 0.185 97 25 0.258 10
F2R F2R P25116 Proteinase-activated receptor 1 chr5 GO:0048584 Not Cancer Driver No 73 0.172 19 2 0.105 0
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0048584 Not Cancer Driver No 55 0.139 7 2 0.286 0
F2RL2 F2RL2 O00254 Proteinase-activated receptor 3 chr5 GO:0048584 Not Cancer Driver No 54 0.144 0 0 0.0 0
F2RL3 F2RL3 Q96RI0 Proteinase-activated receptor 4 chr19 GO:0048584 Not Cancer Driver No 43 0.112 46 4 0.087 0
F3 F3 P13726 Tissue factor chr1 GO:0048584 Not Cancer Driver No 28 0.095 61 7 0.115 0
F7 F7 P08709 Coagulation factor VII chr13 GO:0048584 Not Cancer Driver No 74 0.159 50 7 0.14 108
FABP5 FABP5 Q01469 Fatty acid-binding protein 5 chr8 GO:0048584 Not Cancer Driver No 15 0.111 4 4 1.0 0
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0048584 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAF1 FAF1 Q9UNN5 FAS-associated factor 1 chr1 GO:0048584 Not Cancer Driver No 83 0.128 241 34 0.141 0
FAM168A FAM168A Q92567 Protein FAM168A chr11 GO:0048584 Not Cancer Driver No 17 0.07 139 11 0.079 0
FAM19A3_ENST00000361886 TAFA3 Q7Z5A8 Chemokine-like protein TAFA-3 chr1 GO:0048584 Not Cancer Driver No 17 0.128 6 0 0.0 0
FAM49B_ENST00000519540 CYRIB Q9NUQ9 CYFIP-related Rac1 interactor B chr8 GO:0048584 Not Cancer Driver No 53 0.164 78 11 0.141 0
FAM92A CIBAR1 A1XBS5 CBY1-interacting BAR domain-containing protein 1 chr8 GO:0048584 Not Cancer Driver No 32 0.111 128 17 0.133 0
FANCB FANCB Q8NB91 Fanconi anemia group B protein chrX GO:0048584 Not Cancer Driver No 109 0.127 24 5 0.208 0
FASLG FASLG P48023 Tumor necrosis factor ligand superfamily member 6 chr1 GO:0048584 Not Cancer Driver No 65 0.231 94 18 0.191 1
FBH1_ENST00000362091 FBH1 Q8NFZ0 F-box DNA helicase 1 chr10 GO:0048584 Not Cancer Driver No 139 0.133 192 32 0.167 0
FBXL15 FBXL15 Q9H469 F-box/LRR-repeat protein 15 chr10 GO:0048584 Not Cancer Driver No 9 0.03 16 1 0.062 0
FBXO38_ENST00000340253 FBXO38 Q6PIJ6 F-box only protein 38 chr5 GO:0048584 Not Cancer Driver No 133 0.112 440 48 0.109 1
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 GO:0048584 Census, Compendium Yes 322 0.455 230 38 0.165 0
FCER1G FCER1G P30273 High affinity immunoglobulin epsilon receptor subunit gamma chr1 GO:0048584 Not Cancer Driver No 10 0.116 13 2 0.154 0
FCER2 FCER2 P06734 Low affinity immunoglobulin epsilon Fc receptor chr19 GO:0048584 Not Cancer Driver No 41 0.128 130 22 0.169 0
FCGR2B FCGR2B P31994 Low affinity immunoglobulin gamma Fc region receptor II-b chr1 GO:0048584 Census Yes 51 0.165 99 30 0.303 0
FCN1 FCN1 O00602 Ficolin-1 chr9 GO:0048584 Not Cancer Driver No 107 0.328 88 15 0.17 0
FCN2 FCN2 Q15485 Ficolin-2 chr9 GO:0048584 Not Cancer Driver No 73 0.233 80 19 0.237 0
FCN3 FCN3 O75636 Ficolin-3 chr1 GO:0048584 Not Cancer Driver No 46 0.154 65 19 0.292 0
FERMT1 FERMT1 Q9BQL6 Fermitin family homolog 1 chr20 GO:0048584 Not Cancer Driver No 100 0.148 65 8 0.123 2
FERMT2_ENST00000395631 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 GO:0048584 Not Cancer Driver No 71 0.104 101 10 0.099 0
FFAR2 FFAR2 O15552 Free fatty acid receptor 2 chr19 GO:0048584 Not Cancer Driver No 49 0.148 32 7 0.219 0
FFAR3 FFAR3 O14843 Free fatty acid receptor 3 chr19 GO:0048584 Not Cancer Driver No 78 0.225 29 6 0.207 0
FFAR4_ENST00000371481 FFAR4 Q5NUL3 Free fatty acid receptor 4 chr10 GO:0048584 Not Cancer Driver No 47 0.13 0 0 0.0 0
FGD2 FGD2 Q7Z6J4 FYVE, RhoGEF and PH domain-containing protein 2 chr6 GO:0048584 Not Cancer Driver No 113 0.173 158 26 0.165 0
FGF10 FGF10 O15520 Fibroblast growth factor 10 chr5 GO:0048584 Not Cancer Driver No 56 0.269 34 11 0.324 2
FGF16 FGF16 O43320 Fibroblast growth factor 16 chrX GO:0048584 Not Cancer Driver No 29 0.14 28 6 0.214 1
FGF18 FGF18 O76093 Fibroblast growth factor 18 chr5 GO:0048584 Not Cancer Driver No 40 0.193 57 14 0.246 0
FGF21 FGF21 Q9NSA1 Fibroblast growth factor 21 chr19 GO:0048584 Not Cancer Driver No 37 0.177 109 24 0.22 0
FGF23 FGF23 Q9GZV9 Fibroblast growth factor 23 chr12 GO:0048584 Not Cancer Driver No 84 0.335 97 51 0.526 7
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0048584 Not Cancer Driver No 18 0.062 183 5 0.027 0
FGF8_ENST00000344255 FGF8 P55075 Fibroblast growth factor 8 chr10 GO:0048584 Not Cancer Driver No 30 0.129 79 9 0.114 6
FGF9 FGF9 P31371 Fibroblast growth factor 9 chr13 GO:0048584 Not Cancer Driver No 41 0.197 43 10 0.233 1
FGFBP1 FGFBP1 Q14512 Fibroblast growth factor-binding protein 1 chr4 GO:0048584 Not Cancer Driver No 28 0.12 81 8 0.099 0
FGFBP3 FGFBP3 Q8TAT2 Fibroblast growth factor-binding protein 3 chr10 GO:0048584 Not Cancer Driver No 6 0.023 175 3 0.017 0
FGFR1_ENST00000447712 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 GO:0048584 Census, Compendium Yes 152 0.185 230 43 0.187 74
FGR_ENST00000374004 FGR P09769 Tyrosine-protein kinase Fgr chr1 GO:0048584 Not Cancer Driver No 85 0.161 52 8 0.154 0
FIS1 FIS1 Q9Y3D6 Mitochondrial fission 1 protein chr7 GO:0048584 Not Cancer Driver No 25 0.164 6 0 0.0 0
FKBP1B FKBP1B P68106 Peptidyl-prolyl cis-trans isomerase FKBP1B chr2 GO:0048584 Not Cancer Driver No 10 0.093 58 4 0.069 0
FKBP8_ENST00000222308 FKBP8 Q14318 Peptidyl-prolyl cis-trans isomerase FKBP8 chr19 GO:0048584 Not Cancer Driver No 71 0.172 160 25 0.156 0
FLCN FLCN Q8NFG4 Folliculin chr17 GO:0048584 Census, Compendium Yes 59 0.102 157 19 0.121 5
FLNA FLNA P21333 Filamin-A chrX GO:0048584 Census Yes 416 0.157 1456 214 0.147 28
FLOT1 FLOT1 O75955 Flotillin-1 chr6 GO:0048584 Not Cancer Driver No 43 0.101 122 15 0.123 0
FLT1 FLT1 P17948 Vascular endothelial growth factor receptor 1 chr13 GO:0048584 Not Cancer Driver No 299 0.223 103 20 0.194 0
FLT3 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 GO:0048584 Census, Compendium Yes 200 0.201 64 27 0.422 0
FLT4 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 GO:0048584 Census, Compendium Yes 253 0.186 259 41 0.158 13
FMN2 FMN2 Q9NZ56 Formin-2 chr1 GO:0048584 Not Cancer Driver No 614 0.357 1322 475 0.359 0
FN1 FN1 P02751 Fibronectin chr2 GO:0048584 Compendium Yes 394 0.159 1243 185 0.149 8
FOXA1 FOXA1 P55317 Hepatocyte nuclear factor 3-alpha chr14 GO:0048584 Census, Compendium Yes 100 0.212 295 53 0.18 0
FOXC2 FOXC2 Q99958 Forkhead box protein C2 chr16 GO:0048584 Not Cancer Driver No 63 0.126 369 33 0.089 1
FOXD1 FOXD1 Q16676 Forkhead box protein D1 chr5 GO:0048584 Not Cancer Driver No 10 0.022 259 5 0.019 0
FOXM1_ENST00000359843 FOXM1 Q08050 Forkhead box protein M1 chr12 GO:0048584 Not Cancer Driver No 97 0.127 601 73 0.121 0
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0048584 Census, Compendium Yes 70 0.104 595 68 0.114 0
FOXP1_ENST00000318789 FOXP1 Q9H334 Forkhead box protein P1 chr3 GO:0048584 Census, Compendium Yes 109 0.161 448 71 0.158 3
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0048584 Not Cancer Driver No 38 0.088 186 16 0.086 10
FPR1_ENST00000304748 FPR1 P21462 fMet-Leu-Phe receptor chr19 GO:0048584 Not Cancer Driver No 99 0.283 18 3 0.167 0
FPR2 FPR2 P25090 N-formyl peptide receptor 2 chr19 GO:0048584 Not Cancer Driver No 96 0.274 26 5 0.192 0
FPR3 FPR3 P25089 N-formyl peptide receptor 3 chr19 GO:0048584 Not Cancer Driver No 82 0.232 28 2 0.071 0
FRMD1 FRMD1 Q8N878 FERM domain-containing protein 1 chr6 GO:0048584 Not Cancer Driver No 82 0.149 259 36 0.139 0
FRMD7 FRMD7 Q6ZUT3 FERM domain-containing protein 7 chrX GO:0048584 Not Cancer Driver No 147 0.206 256 59 0.23 25
FSHR FSHR P23945 Follicle-stimulating hormone receptor chr2 GO:0048584 Not Cancer Driver No 226 0.325 28 11 0.393 16
FUS FUS P35637 RNA-binding protein FUS chr16 GO:0048584 Census Yes 51 0.097 524 51 0.097 20
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0048584 Not Cancer Driver No 92 0.171 70 13 0.186 0
FZD10 FZD10 Q9ULW2 Frizzled-10 chr12 GO:0048584 Not Cancer Driver No 148 0.255 65 15 0.231 0
FZD4 FZD4 Q9ULV1 Frizzled-4 chr11 GO:0048584 Not Cancer Driver No 57 0.106 33 5 0.152 19
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:0048584 Not Cancer Driver No 45 0.077 58 4 0.069 0
FZD8 FZD8 Q9H461 Frizzled-8 chr10 GO:0048584 Not Cancer Driver No 72 0.104 146 3 0.021 0
GAB2 GAB2 Q9UQC2 GRB2-associated-binding protein 2 chr11 GO:0048584 Not Cancer Driver No 85 0.126 537 73 0.136 0
GADD45A GADD45A P24522 Growth arrest and DNA damage-inducible protein GADD45 alpha chr1 GO:0048584 Not Cancer Driver No 10 0.061 39 5 0.128 0
GADD45B GADD45B O75293 Growth arrest and DNA damage-inducible protein GADD45 beta chr19 GO:0048584 Not Cancer Driver No 9 0.056 14 0 0.0 0
GADD45G GADD45G O95257 Growth arrest and DNA damage-inducible protein GADD45 gamma chr9 GO:0048584 Not Cancer Driver No 13 0.082 20 2 0.1 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0048584 Not Cancer Driver No 82 0.121 42 6 0.143 0
GAS8 GAS8 O95995 Dynein regulatory complex subunit 4 chr16 GO:0048584 Not Cancer Driver No 54 0.113 232 29 0.125 1
GATA1 GATA1 P15976 Erythroid transcription factor chrX GO:0048584 Census, Compendium Yes 68 0.165 242 41 0.169 5
GATA2_ENST00000487848 GATA2 P23769 Endothelial transcription factor GATA-2 chr3 GO:0048584 Census, Compendium Yes 72 0.15 370 49 0.132 6
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0048584 Census, Compendium Yes 111 0.251 364 87 0.239 2
GATA4_ENST00000335135 GATA4 P43694 Transcription factor GATA-4 chr8 GO:0048584 Not Cancer Driver No 48 0.109 301 34 0.113 18
GATA5 GATA5 Q9BWX5 Transcription factor GATA-5 chr20 GO:0048584 Not Cancer Driver No 40 0.101 268 24 0.09 9
GATA6 GATA6 Q92908 Transcription factor GATA-6 chr18 GO:0048584 Not Cancer Driver No 57 0.096 476 51 0.107 10
GDF1 GDF1 P27539 Embryonic growth/differentiation factor 1 chr19 GO:0048584 Not Cancer Driver No 8 0.022 144 5 0.035 6
GDF11 GDF11 O95390 Growth/differentiation factor 11 chr12 GO:0048584 Not Cancer Driver No 40 0.098 109 7 0.064 1
GDF15 GDF15 Q99988 Growth/differentiation factor 15 chr19 GO:0048584 Not Cancer Driver No 39 0.127 143 20 0.14 0
GDF3 GDF3 Q9NR23 Growth/differentiation factor 3 chr12 GO:0048584 Not Cancer Driver No 79 0.217 3 3 1.0 5
GDF5_ENST00000374369 GDF5 P43026 Growth/differentiation factor 5 chr20 GO:0048584 Not Cancer Driver No 104 0.208 255 50 0.196 24
GDF6 GDF6 Q6KF10 Growth/differentiation factor 6 chr8 GO:0048584 Not Cancer Driver No 91 0.2 225 46 0.204 14
GDF7 GDF7 Q7Z4P5 Growth/differentiation factor 7 chr2 GO:0048584 Not Cancer Driver No 33 0.073 213 8 0.038 0
GDF9 GDF9 O60383 Growth/differentiation factor 9 chr5 GO:0048584 Not Cancer Driver No 72 0.159 53 15 0.283 0
GEN1_ENST00000381254 GEN1 Q17RS7 Flap endonuclease GEN homolog 1 chr2 GO:0048584 Not Cancer Driver No 109 0.12 339 52 0.153 0
GFI1 GFI1 Q99684 Zinc finger protein Gfi-1 chr1 GO:0048584 Not Cancer Driver No 57 0.135 199 29 0.146 2
GH1 GH1 P01241 Somatotropin chr17 GO:0048584 Not Cancer Driver No 54 0.249 24 9 0.375 15
GHRHR GHRHR Q02643 Growth hormone-releasing hormone receptor chr7 GO:0048584 Not Cancer Driver No 41 0.097 3 0 0.0 5
GHRH_ENST00000237527 GHRH P01286 Somatoliberin chr20 GO:0048584 Not Cancer Driver No 13 0.12 36 4 0.111 0
GHRL_ENST00000457360 GHRL Q9UBU3 Appetite-regulating hormone chr3 GO:0048584 Not Cancer Driver No 20 0.171 52 11 0.212 0
GHSR GHSR Q92847 Growth hormone secretagogue receptor type 1 chr3 GO:0048584 Not Cancer Driver No 85 0.232 4 0 0.0 2
GIP GIP P09681 Gastric inhibitory polypeptide chr17 GO:0048584 Not Cancer Driver No 35 0.229 68 16 0.235 0
GIPC1 GIPC1 O14908 PDZ domain-containing protein GIPC1 chr19 GO:0048584 Not Cancer Driver No 47 0.141 138 17 0.123 0
GIPR GIPR P48546 Gastric inhibitory polypeptide receptor chr19 GO:0048584 Not Cancer Driver No 45 0.097 41 0 0.0 0
GKAP1 GKAP1 Q5VSY0 G kinase-anchoring protein 1 chr9 GO:0048584 Not Cancer Driver No 39 0.107 279 29 0.104 0
GLI1 GLI1 P08151 Zinc finger protein GLI1 chr12 GO:0048584 Census, Compendium Yes 206 0.186 1015 184 0.181 0
GNAI2 GNAI2 P04899 Guanine nucleotide-binding protein G(i) subunit alpha-2 chr3 GO:0048584 Compendium Yes 50 0.141 24 0 0.0 0
GPC3_ENST00000370818 GPC3 P51654 Glypican-3 chrX GO:0048584 Census Yes 89 0.153 86 11 0.128 1
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0048584 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0048584 Not Cancer Driver No 153 0.182 36 9 0.25 0
GPR137B GPR137B O60478 Integral membrane protein GPR137B chr1 GO:0048584 Not Cancer Driver No 49 0.123 47 1 0.021 0
GPR137C GPR137C Q8N3F9 Integral membrane protein GPR137C chr14 GO:0048584 Not Cancer Driver No 41 0.096 47 0 0.0 0
GPR137_ENST00000313074 GPR137 Q96N19 Integral membrane protein GPR137 chr11 GO:0048584 Not Cancer Driver No 66 0.158 41 11 0.268 0
GPR17 GPR17 Q13304 Uracil nucleotide/cysteinyl leukotriene receptor chr2 GO:0048584 Not Cancer Driver No 57 0.155 16 4 0.25 0
GPR174_ENST00000276077 GPR174 Q9BXC1 Probable G-protein coupled receptor 174 chrX GO:0048584 Not Cancer Driver No 115 0.345 0 0 0.0 0
GPR18_ENST00000397470 GPR18 Q14330 N-arachidonyl glycine receptor chr13 GO:0048584 Not Cancer Driver No 36 0.109 0 0 0.0 0
GPR20 GPR20 Q99678 G-protein coupled receptor 20 chr8 GO:0048584 Not Cancer Driver No 77 0.215 44 11 0.25 0
GPR27 GPR27 Q9NS67 Probable G-protein coupled receptor 27 chr3 GO:0048584 Not Cancer Driver No 26 0.069 23 1 0.043 0
GPR3 GPR3 P46089 G-protein coupled receptor 3 chr1 GO:0048584 Not Cancer Driver No 38 0.115 13 1 0.077 0
GPR32 GPR32 O75388 Probable G-protein coupled receptor 32 chr19 GO:0048584 Not Cancer Driver No 85 0.239 18 6 0.333 0
GPR35_ENST00000403859 GPR35 Q9HC97 G-protein coupled receptor 35 chr2 GO:0048584 Not Cancer Driver No 57 0.184 0 0 0.0 0
GPR4 GPR4 P46093 G-protein coupled receptor 4 chr19 GO:0048584 Not Cancer Driver No 57 0.157 44 8 0.182 0
GPR55 GPR55 Q9Y2T6 G-protein coupled receptor 55 chr2 GO:0048584 Not Cancer Driver No 64 0.201 0 0 0.0 0
GPR61_ENST00000618721 GPR61 Q9BZJ8 G-protein coupled receptor 61 chr1 GO:0048584 Not Cancer Driver No 72 0.16 103 23 0.223 0
GPR62 GPR62 Q9BZJ7 G-protein coupled receptor 62 chr3 GO:0048584 Not Cancer Driver No 20 0.054 52 9 0.173 0
GPR65 GPR65 Q8IYL9 Psychosine receptor chr14 GO:0048584 Not Cancer Driver No 70 0.208 0 0 0.0 0
GPS2 GPS2 Q13227 G protein pathway suppressor 2 chr17 GO:0048584 Not Cancer Driver No 29 0.089 319 26 0.082 0
GRB10_ENST00000401949 GRB10 Q13322 Growth factor receptor-bound protein 10 chr7 GO:0048584 Not Cancer Driver No 94 0.158 220 38 0.173 0
GRIN1_ENST00000371561 GRIN1 Q05586 Glutamate receptor ionotropic, NMDA 1 chr9 GO:0048584 Not Cancer Driver No 88 0.094 190 15 0.079 13
GRN GRN P28799 Progranulin chr17 GO:0048584 Not Cancer Driver No 76 0.128 29 6 0.207 1
GRP GRP P07492 Gastrin-releasing peptide chr18 GO:0048584 Not Cancer Driver No 37 0.25 112 22 0.196 0
GSDME_ENST00000409775 GSDME O60443 Gasdermin-E chr7 GO:0048584 Not Cancer Driver No 81 0.163 14 3 0.214 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0048584 Not Cancer Driver No 55 0.114 180 8 0.044 0
GSX2 GSX2 Q9BZM3 GS homeobox 2 chr4 GO:0048584 Not Cancer Driver No 44 0.145 210 26 0.124 1
GUCA1A GUCA1A P43080 Guanylyl cyclase-activating protein 1 chr6 GO:0048584 Not Cancer Driver No 39 0.194 20 4 0.2 17
GUCY1A1_ENST00000513574 GUCY1A1 Q02108 Guanylate cyclase soluble subunit alpha-1 chr4 GO:0048584 Not Cancer Driver No 181 0.262 54 8 0.148 0
GUCY1A2_ENST00000526355 GUCY1A2 P33402 Guanylate cyclase soluble subunit alpha-2 chr11 GO:0048584 Not Cancer Driver No 191 0.261 187 48 0.257 0
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0048584 Not Cancer Driver No 47 0.217 124 29 0.234 0
HAP1_ENST00000310778 HAP1 P54257 Huntingtin-associated protein 1 chr17 GO:0048584 Not Cancer Driver No 97 0.145 454 60 0.132 0
HAVCR2 HAVCR2 Q8TDQ0 Hepatitis A virus cellular receptor 2 chr5 GO:0048584 Not Cancer Driver No 69 0.229 17 2 0.118 3
HAX1 HAX1 O00165 HCLS1-associated protein X-1 chr1 GO:0048584 Not Cancer Driver No 44 0.158 219 32 0.146 2
HBEGF HBEGF Q99075 Proheparin-binding EGF-like growth factor chr5 GO:0048584 Not Cancer Driver No 16 0.077 63 3 0.048 0
HCK_ENST00000534862 HCK P08631 Tyrosine-protein kinase HCK chr20 GO:0048584 Not Cancer Driver No 112 0.213 124 25 0.202 0
HCLS1 HCLS1 P14317 Hematopoietic lineage cell-specific protein chr3 GO:0048584 Not Cancer Driver No 103 0.212 446 94 0.211 0
HCST HCST Q9UBK5 Hematopoietic cell signal transducer chr19 GO:0048584 Not Cancer Driver No 6 0.065 12 0 0.0 0
HDAC10 HDAC10 Q969S8 Polyamine deacetylase HDAC10 chr22 GO:0048584 Not Cancer Driver No 67 0.1 121 11 0.091 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX GO:0048584 Not Cancer Driver No 178 0.147 409 59 0.144 0
HDGFL2 HDGFL2 Q7Z4V5 Hepatoma-derived growth factor-related protein 2 chr19 GO:0048584 Not Cancer Driver No 59 0.088 622 57 0.092 0
HERPUD1 HERPUD1 Q15011 Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein chr16 GO:0048584 Census Yes 38 0.097 248 17 0.069 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0048584 Not Cancer Driver No 37 0.132 226 32 0.142 0
HES5 HES5 Q5TA89 Transcription factor HES-5 chr1 GO:0048584 Not Cancer Driver No 1 0.006 73 0 0.0 0
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 GO:0048584 Not Cancer Driver No 40 0.111 352 40 0.114 0
HFE HFE Q30201 Hereditary hemochromatosis protein chr6 GO:0048584 Not Cancer Driver No 55 0.158 27 2 0.074 11
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0048584 Compendium Yes 233 0.32 43 16 0.372 0
HIC1 HIC1 Q14526 Hypermethylated in cancer 1 protein chr17 GO:0048584 Not Cancer Driver No 24 0.033 361 6 0.017 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0048584 Census Yes 118 0.143 435 51 0.117 0
HINT1 HINT1 P49773 Adenosine 5'-monophosphoramidase HINT1 chr5 GO:0048584 Not Cancer Driver No 11 0.087 6 0 0.0 6
HIP1 HIP1 O00291 Huntingtin-interacting protein 1 chr7 GO:0048584 Census, Compendium Yes 137 0.132 510 70 0.137 0
HIP1R HIP1R O75146 Huntingtin-interacting protein 1-related protein chr12 GO:0048584 Not Cancer Driver No 94 0.088 524 34 0.065 0
HIPK2 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 GO:0048584 Not Cancer Driver No 154 0.129 686 96 0.14 0
HLA-A_ENST00000376809 HLA-A P04439 HLA class I histocompatibility antigen, A alpha chain chr6 GO:0048584 Census, Compendium Yes 128 0.351 125 60 0.48 0
HLA-B HLA-B P01889 HLA class I histocompatibility antigen, B alpha chain chr6 GO:0048584 Compendium Yes 78 0.215 169 34 0.201 0
HLA-DMB HLA-DMB P28068 HLA class II histocompatibility antigen, DM beta chain chr6 GO:0048584 Not Cancer Driver No 41 0.156 41 9 0.22 0
HLA-DRA HLA-DRA P01903 HLA class II histocompatibility antigen, DR alpha chain chr6 GO:0048584 Not Cancer Driver No 52 0.205 12 1 0.083 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0048584 Not Cancer Driver No 48 0.18 12 1 0.083 0
HLA-E HLA-E P13747 HLA class I histocompatibility antigen, alpha chain E chr6 GO:0048584 Not Cancer Driver No 63 0.176 138 39 0.283 0
HLA-F_ENST00000376861 HLA-F P30511 HLA class I histocompatibility antigen, alpha chain F chr6 GO:0048584 Not Cancer Driver No 43 0.124 115 22 0.191 0
HLA-G_ENST00000360323 HLA-G P17693 HLA class I histocompatibility antigen, alpha chain G chr6 GO:0048584 Not Cancer Driver No 94 0.278 85 22 0.259 0
HLX HLX Q14774 H2.0-like homeobox protein chr1 GO:0048584 Not Cancer Driver No 107 0.219 412 98 0.238 0
HMCES_ENST00000502878 HMCES Q96FZ2 Abasic site processing protein HMCES chr3 GO:0048584 Not Cancer Driver No 37 0.105 131 16 0.122 0
HMGA2_ENST00000403681 HMGA2 P52926 High mobility group protein HMGI-C chr12 GO:0048584 Census Yes 12 0.11 109 12 0.11 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0048584 Not Cancer Driver No 25 0.116 203 20 0.099 0
HPSE HPSE Q9Y251 Heparanase chr4 GO:0048584 Not Cancer Driver No 90 0.166 16 2 0.125 0
HPX HPX P02790 Hemopexin chr11 GO:0048584 Not Cancer Driver No 60 0.13 53 8 0.151 0
HRG HRG P04196 Histidine-rich glycoprotein chr3 GO:0048584 Not Cancer Driver No 121 0.23 277 75 0.271 2
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0048584 Census, Compendium Yes 100 0.138 254 43 0.169 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0048584 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPA1B HSPA1B P0DMV9 Heat shock 70 kDa protein 1B chr6 GO:0048584 Not Cancer Driver No 15 0.023 200 5 0.025 0
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 GO:0048584 Not Cancer Driver No 10 0.049 118 8 0.068 20
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 GO:0048584 Not Cancer Driver No 61 0.106 82 6 0.073 2
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 GO:0048584 Compendium Yes 44 0.096 127 9 0.071 2
HTT HTT P42858 Huntingtin chr4 GO:0048584 Not Cancer Driver No 336 0.107 666 69 0.104 2
IAPP_ENST00000539393 IAPP P10997 Islet amyloid polypeptide chr12 GO:0048584 Not Cancer Driver No 22 0.247 10 2 0.2 0
IDO1_ENST00000522495 IDO1 P14902 Indoleamine 2,3-dioxygenase 1 chr8 GO:0048584 Not Cancer Driver No 82 0.203 41 8 0.195 0
IER5 IER5 Q5VY09 Immediate early response gene 5 protein chr1 GO:0048584 Not Cancer Driver No 20 0.061 271 15 0.055 0
IFI35_ENST00000415816 IFI35 P80217 Interferon-induced 35 kDa protein chr17 GO:0048584 Not Cancer Driver No 33 0.115 63 10 0.159 0
IFIH1 IFIH1 Q9BYX4 Interferon-induced helicase C domain-containing protein 1 chr2 GO:0048584 Not Cancer Driver No 109 0.106 287 36 0.125 9
IFNG IFNG P01579 Interferon gamma chr12 GO:0048584 Not Cancer Driver No 51 0.307 23 6 0.261 0
IFT172 IFT172 Q9UG01 Intraflagellar transport protein 172 homolog chr2 GO:0048584 Not Cancer Driver No 219 0.125 96 10 0.104 8
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0048584 Not Cancer Driver No 183 0.134 265 37 0.14 6
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0048584 Not Cancer Driver No 45 0.231 87 23 0.264 0
IGF2_ENST00000641326 IGF2 P01344 Insulin-like growth factor II chr11 GO:0048584 Not Cancer Driver No 39 0.217 44 12 0.273 0
IGFBP4 IGFBP4 P22692 Insulin-like growth factor-binding protein 4 chr17 GO:0048584 Not Cancer Driver No 24 0.093 106 17 0.16 0
IGFBP5 IGFBP5 P24593 Insulin-like growth factor-binding protein 5 chr2 GO:0048584 Not Cancer Driver No 27 0.099 112 17 0.152 0
IGHD IGHD P01880 Immunoglobulin heavy constant delta chr14 GO:0048584 Not Cancer Driver No 61 0.159 245 40 0.163 0
IGLL1 IGLL1 P15814 Immunoglobulin lambda-like polypeptide 1 chr22 GO:0048584 Not Cancer Driver No 25 0.117 144 18 0.125 1
IGLL5 IGLL5 B9A064 Immunoglobulin lambda-like polypeptide 5 chr22 GO:0048584 Not Cancer Driver No 59 0.276 127 35 0.276 0
IGSF11 IGSF11 Q5DX21 Immunoglobulin superfamily member 11 chr3 GO:0048584 Not Cancer Driver No 98 0.227 159 28 0.176 0
IHH IHH Q14623 Indian hedgehog protein chr2 GO:0048584 Not Cancer Driver No 58 0.141 111 15 0.135 6
IKBKB IKBKB O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta chr8 GO:0048584 Census, Compendium Yes 106 0.14 211 31 0.147 1
IKBKE IKBKE Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon chr1 GO:0048584 Not Cancer Driver No 108 0.151 76 13 0.171 0
IKBKG_ENST00000611071 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX GO:0048584 Not Cancer Driver No 6 0.014 301 6 0.02 22
IL10 IL10 P22301 Interleukin-10 chr1 GO:0048584 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0048584 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL12RB1_ENST00000593993 IL12RB1 P42701 Interleukin-12 receptor subunit beta-1 chr19 GO:0048584 Not Cancer Driver No 108 0.163 207 38 0.184 1
IL13 IL13 P35225 Interleukin-13 chr5 GO:0048584 Not Cancer Driver No 20 0.137 0 0 0.0 0
IL16 IL16 Q14005 Pro-interleukin-16 chr15 GO:0048584 Not Cancer Driver No 216 0.162 959 151 0.157 0
IL17A IL17A Q16552 Interleukin-17A chr6 GO:0048584 Not Cancer Driver No 52 0.335 56 21 0.375 0
IL17F IL17F Q96PD4 Interleukin-17F chr6 GO:0048584 Not Cancer Driver No 42 0.258 34 11 0.324 1
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0048584 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL18R1_ENST00000233957 IL18R1 Q13478 Interleukin-18 receptor 1 chr2 GO:0048584 Not Cancer Driver No 104 0.192 18 3 0.167 0
IL19_ENST00000270218 IL19 Q9UHD0 Interleukin-19 chr1 GO:0048584 Not Cancer Driver No 16 0.09 0 0 0.0 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0048584 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL1R1 IL1R1 P14778 Interleukin-1 receptor type 1 chr2 GO:0048584 Not Cancer Driver No 77 0.135 59 8 0.136 0
IL2 IL2 P60568 Interleukin-2 chr4 GO:0048584 Census Yes 24 0.157 6 1 0.167 0
IL20RA IL20RA Q9UHF4 Interleukin-20 receptor subunit alpha chr6 GO:0048584 Not Cancer Driver No 72 0.13 231 29 0.126 0
IL23A IL23A Q9NPF7 Interleukin-23 subunit alpha chr12 GO:0048584 Not Cancer Driver No 15 0.079 42 3 0.071 0
IL23R IL23R Q5VWK5 Interleukin-23 receptor chr1 GO:0048584 Not Cancer Driver No 70 0.111 117 19 0.162 0
IL27RA IL27RA Q6UWB1 Interleukin-27 receptor subunit alpha chr19 GO:0048584 Not Cancer Driver No 91 0.143 167 23 0.138 0
IL33 IL33 O95760 Interleukin-33 chr9 GO:0048584 Not Cancer Driver No 47 0.174 47 8 0.17 0
IL34 IL34 Q6ZMJ4 Interleukin-34 chr16 GO:0048584 Not Cancer Driver No 22 0.091 42 6 0.143 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:0048584 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL4R_ENST00000543915 IL4R P24394 Interleukin-4 receptor subunit alpha chr16 GO:0048584 Not Cancer Driver No 133 0.161 420 64 0.152 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0048584 Not Cancer Driver No 35 0.165 58 7 0.121 0
IL6ST_ENST00000336909 IL6ST P40189 Interleukin-6 receptor subunit beta chr5 GO:0048584 Census, Compendium Yes 102 0.111 315 40 0.127 2
IL7 IL7 P13232 Interleukin-7 chr8 GO:0048584 Not Cancer Driver No 29 0.164 19 4 0.211 0
ILK_ENST00000299421 ILK Q13418 Integrin-linked protein kinase chr11 GO:0048584 Not Cancer Driver No 45 0.1 71 9 0.127 0
ING2 ING2 Q9H160 Inhibitor of growth protein 2 chr4 GO:0048584 Not Cancer Driver No 33 0.118 169 26 0.154 0
ING3 ING3 Q9NXR8 Inhibitor of growth protein 3 chr7 GO:0048584 Not Cancer Driver No 44 0.105 292 32 0.11 1
ING4 ING4 Q9UNL4 Inhibitor of growth protein 4 chr12 GO:0048584 Not Cancer Driver No 31 0.124 108 15 0.139 0
INHA INHA P05111 Inhibin alpha chain chr2 GO:0048584 Not Cancer Driver No 48 0.131 144 15 0.104 0
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:0048584 Not Cancer Driver No 148 0.347 154 63 0.409 0
INHBB INHBB P09529 Inhibin beta B chain chr2 GO:0048584 Not Cancer Driver No 61 0.15 98 5 0.051 0
INHBC INHBC P55103 Inhibin beta C chain chr12 GO:0048584 Not Cancer Driver No 52 0.148 35 3 0.086 0
INHBE INHBE P58166 Inhibin beta E chain chr12 GO:0048584 Not Cancer Driver No 52 0.149 85 12 0.141 0
INS INS P01308 Insulin chr11 GO:0048584 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSL3_ENST00000317306 INSL3 P51460 Insulin-like 3 chr19 GO:0048584 Not Cancer Driver No 18 0.137 34 12 0.353 3
INSR INSR P06213 Insulin receptor chr19 GO:0048584 Not Cancer Driver No 190 0.137 280 57 0.204 64
INTU INTU Q9ULD6 Protein inturned chr4 GO:0048584 Not Cancer Driver No 146 0.155 282 52 0.184 0
IQCJ-SCHIP1 IQCJ-SCHIP1 B3KU38 IQCJ-SCHIP1 readthrough transcript protein chr3 GO:0048584 Not Cancer Driver No 76 0.135 517 71 0.137 0
IRF3_ENST00000597198 IRF3 Q14653 Interferon regulatory factor 3 chr19 GO:0048584 Not Cancer Driver No 36 0.084 204 21 0.103 1
IRF7_ENST00000397574 IRF7 Q92985 Interferon regulatory factor 7 chr11 GO:0048584 Not Cancer Driver No 43 0.085 253 19 0.075 1
IRGM IRGM A1A4Y4 Immunity-related GTPase family M protein chr5 GO:0048584 Not Cancer Driver No 9 0.05 45 1 0.022 0
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 GO:0048584 Not Cancer Driver No 161 0.13 1072 133 0.124 2
ITGA2 ITGA2 P17301 Integrin alpha-2 chr5 GO:0048584 Not Cancer Driver No 166 0.141 26 0 0.0 0
ITGA5 ITGA5 P08648 Integrin alpha-5 chr12 GO:0048584 Not Cancer Driver No 127 0.121 201 29 0.144 0
ITGA8 ITGA8 P53708 Integrin alpha-8 chr10 GO:0048584 Not Cancer Driver No 292 0.275 114 26 0.228 1
ITGAM_ENST00000287497 ITGAM P11215 Integrin alpha-M chr16 GO:0048584 Not Cancer Driver No 191 0.166 133 12 0.09 0
ITGAV ITGAV P06756 Integrin alpha-V chr2 GO:0048584 Census Yes 153 0.146 92 9 0.098 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0048584 Not Cancer Driver No 26 0.13 58 11 0.19 0
ITGB2_ENST00000355153 ITGB2 P05107 Integrin beta-2 chr21 GO:0048584 Not Cancer Driver No 147 0.191 59 9 0.153 15
ITGB3 ITGB3 P05106 Integrin beta-3 chr17 GO:0048584 Not Cancer Driver No 124 0.157 66 5 0.076 30
JAG1 JAG1 P78504 Protein jagged-1 chr20 GO:0048584 Not Cancer Driver No 182 0.149 172 20 0.116 52
JAG2 JAG2 Q9Y219 Protein jagged-2 chr14 GO:0048584 Not Cancer Driver No 126 0.102 158 24 0.152 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0048584 Census, Compendium Yes 136 0.12 59 5 0.085 5
JCAD JCAD Q9P266 Junctional protein associated with coronary artery disease chr10 GO:0048584 Not Cancer Driver No 291 0.214 1337 290 0.217 0
KARS_ENST00000302445 KARS1 Q15046 Lysine--tRNA ligase chr16 GO:0048584 Not Cancer Driver No 88 0.147 160 15 0.094 12
KAT5_ENST00000377046 KAT5 Q92993 Histone acetyltransferase KAT5 chr11 GO:0048584 Not Cancer Driver No 65 0.127 173 21 0.121 3
KCNK2 KCNK2 O95069 Potassium channel subfamily K member 2 chr1 GO:0048584 Not Cancer Driver No 109 0.256 40 10 0.25 0
KCNN4 KCNN4 O15554 Intermediate conductance calcium-activated potassium channel protein 4 chr19 GO:0048584 Not Cancer Driver No 60 0.141 31 6 0.194 3
KDM4D_ENST00000610872 KDM4D Q6B0I6 Lysine-specific demethylase 4D chr11 GO:0048584 Not Cancer Driver No 78 0.149 215 33 0.153 0
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0048584 Census, Compendium Yes 357 0.263 275 55 0.2 2
KHDC3L KHDC3L Q587J8 KH domain-containing protein 3 chr6 GO:0048584 Not Cancer Driver No 68 0.313 121 43 0.355 0
KIAA0319_ENST00000543707 KIAA0319 Q5VV43 Dyslexia-associated protein KIAA0319 chr6 GO:0048584 Not Cancer Driver No 204 0.19 492 85 0.173 0
KIAA1324L ELAPOR2 A8MWY0 Endosome/lysosome-associated apoptosis and autophagy regulator family member 2 chr7 GO:0048584 Not Cancer Driver No 170 0.165 74 6 0.081 0
KIF7 KIF7 Q2M1P5 Kinesin-like protein KIF7 chr15 GO:0048584 Not Cancer Driver No 150 0.112 844 104 0.123 5
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0048584 Census, Compendium Yes 226 0.232 83 33 0.398 21
KL KL Q9UEF7 Klotho chr13 GO:0048584 Not Cancer Driver No 175 0.173 104 5 0.048 1
KLB KLB Q86Z14 Beta-klotho chr4 GO:0048584 Not Cancer Driver No 139 0.133 6 1 0.167 0
KLF14 KLF14 Q8TD94 Krueppel-like factor 14 chr7 GO:0048584 Not Cancer Driver No 24 0.074 264 20 0.076 0
KLF2 KLF2 Q9Y5W3 Krueppel-like factor 2 chr19 GO:0048584 Not Cancer Driver No 13 0.037 280 4 0.014 0
KLHL22 KLHL22 Q53GT1 Kelch-like protein 22 chr22 GO:0048584 Not Cancer Driver No 90 0.142 50 8 0.16 0
KLK14_ENST00000156499 KLK14 Q9P0G3 Kallikrein-14 chr19 GO:0048584 Not Cancer Driver No 41 0.154 29 6 0.207 0
KLK3 KLK3 P07288 Prostate-specific antigen chr19 GO:0048584 Not Cancer Driver No 68 0.261 6 1 0.167 0
KLK5_ENST00000593428 KLK5 Q9Y337 Kallikrein-5 chr19 GO:0048584 Not Cancer Driver No 69 0.235 75 16 0.213 0
KLK6 KLK6 Q92876 Kallikrein-6 chr19 GO:0048584 Not Cancer Driver No 62 0.254 28 12 0.429 0
KLK7 KLK7 P49862 Kallikrein-7 chr19 GO:0048584 Not Cancer Driver No 43 0.17 38 8 0.211 0
KLRC2 KLRC2 P26717 NKG2-C type II integral membrane protein chr12 GO:0048584 Not Cancer Driver No 55 0.238 45 17 0.378 0
KLRC3_ENST00000396439 KLRC3 Q07444 NKG2-E type II integral membrane protein chr12 GO:0048584 Not Cancer Driver No 37 0.154 43 4 0.093 0
KLRC4 KLRC4 O43908 NKG2-F type II integral membrane protein chr12 GO:0048584 Not Cancer Driver No 36 0.228 45 7 0.156 0
KLRD1 KLRD1 Q13241 Natural killer cells antigen CD94 chr12 GO:0048584 Not Cancer Driver No 37 0.207 0 0 0.0 0
KLRK1 KLRK1 P26718 NKG2-D type II integral membrane protein chr12 GO:0048584 Not Cancer Driver No 38 0.176 0 0 0.0 0
KMT2D KMT2D O14686 Histone-lysine N-methyltransferase 2D chr12 GO:0048584 Census, Compendium Yes 773 0.14 4386 552 0.126 13
KMT5B_ENST00000615954 KMT5B Q4FZB7 Histone-lysine N-methyltransferase KMT5B chr11 GO:0048584 Not Cancer Driver No 147 0.166 659 113 0.171 0
KMT5C KMT5C Q86Y97 Histone-lysine N-methyltransferase KMT5C chr19 GO:0048584 Not Cancer Driver No 37 0.08 142 9 0.063 0
KRAS KRAS P01116 GTPase KRas chr12 GO:0048584 Census, Compendium Yes 788 4.169 7 2 0.286 27
KRT1 KRT1 P04264 Keratin, type II cytoskeletal 1 chr12 GO:0048584 Not Cancer Driver No 133 0.207 426 98 0.23 20
LACRT LACRT Q9GZZ8 Extracellular glycoprotein lacritin chr12 GO:0048584 Not Cancer Driver No 38 0.275 90 27 0.3 0
LAMP1 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 GO:0048584 Not Cancer Driver No 47 0.113 93 10 0.108 0
LAMTOR5_ENST00000602318 LAMTOR5 O43504 Ragulator complex protein LAMTOR5 chr1 GO:0048584 Not Cancer Driver No 10 0.11 17 0 0.0 0
LANCL2 LANCL2 Q9NS86 LanC-like protein 2 chr7 GO:0048584 Not Cancer Driver No 71 0.158 44 5 0.114 0
LAPTM5 LAPTM5 Q13571 Lysosomal-associated transmembrane protein 5 chr1 GO:0048584 Not Cancer Driver No 46 0.176 16 6 0.375 0
LARS LARS1 Q9P2J5 Leucine--tRNA ligase, cytoplasmic chr5 GO:0048584 Not Cancer Driver No 133 0.113 97 10 0.103 1
LBP LBP P18428 Lipopolysaccharide-binding protein chr20 GO:0048584 Not Cancer Driver No 84 0.175 6 0 0.0 0
LBX2 LBX2 Q6XYB7 Transcription factor LBX2 chr2 GO:0048584 Not Cancer Driver No 16 0.081 139 7 0.05 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 GO:0048584 Census Yes 86 0.169 94 13 0.138 1
LEFTY1 LEFTY1 O75610 Left-right determination factor 1 chr1 GO:0048584 Not Cancer Driver No 55 0.15 65 8 0.123 0
LEFTY2 LEFTY2 O00292 Left-right determination factor 2 chr1 GO:0048584 Not Cancer Driver No 38 0.104 54 4 0.074 1
LEP LEP P41159 Leptin chr7 GO:0048584 Not Cancer Driver No 29 0.174 0 0 0.0 2
LFNG LFNG Q8NES3 Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe chr7 GO:0048584 Not Cancer Driver No 37 0.098 65 1 0.015 1
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0048584 Not Cancer Driver No 54 0.152 65 16 0.246 0
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 GO:0048584 Not Cancer Driver No 57 0.132 112 19 0.17 0
LILRA2 LILRA2 Q8N149 Leukocyte immunoglobulin-like receptor subfamily A member 2 chr19 GO:0048584 Not Cancer Driver No 163 0.337 137 44 0.321 0
LILRB1_ENST00000396331 LILRB1 Q8NHL6 Leukocyte immunoglobulin-like receptor subfamily B member 1 chr19 GO:0048584 Not Cancer Driver No 203 0.312 291 97 0.333 0
LIMK1 LIMK1 P53667 LIM domain kinase 1 chr7 GO:0048584 Not Cancer Driver No 110 0.17 170 30 0.176 0
LIMS1_ENST00000393310 LIMS1 P48059 LIM and senescent cell antigen-like-containing domain protein 1 chr2 GO:0048584 Not Cancer Driver No 34 0.105 0 0 0.0 0
LIMS2_ENST00000355119 LIMS2 Q7Z4I7 LIM and senescent cell antigen-like-containing domain protein 2 chr2 GO:0048584 Not Cancer Driver No 55 0.161 8 0 0.0 0
LMCD1 LMCD1 Q9NZU5 LIM and cysteine-rich domains protein 1 chr3 GO:0048584 Not Cancer Driver No 63 0.173 110 24 0.218 0
LMO3_ENST00000534946 LMO3 Q8TAP4 LIM domain only protein 3 chr12 GO:0048584 Not Cancer Driver No 30 0.207 1 0 0.0 0
LOXL3 LOXL3 P58215 Lysyl oxidase homolog 3 chr2 GO:0048584 Not Cancer Driver No 91 0.121 86 17 0.198 0
LPAR1_ENST00000358883 LPAR1 Q92633 Lysophosphatidic acid receptor 1 chr9 GO:0048584 Not Cancer Driver No 79 0.217 21 6 0.286 0
LPAR4 LPAR4 Q99677 Lysophosphatidic acid receptor 4 chrX GO:0048584 Compendium Yes 123 0.332 10 3 0.3 0
LPAR6_ENST00000620633 LPAR6 P43657 Lysophosphatidic acid receptor 6 chr13 GO:0048584 Not Cancer Driver No 39 0.113 0 0 0.0 3
LRG1 LRG1 P02750 Leucine-rich alpha-2-glycoprotein chr19 GO:0048584 Not Cancer Driver No 63 0.182 29 8 0.276 0
LRRC70 LRRC70 Q7Z2Q7 Leucine-rich repeat-containing protein 70 chr5 GO:0048584 Not Cancer Driver No 32 0.051 20 1 0.05 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0048584 Not Cancer Driver No 519 0.205 90 17 0.189 23
LRSAM1_ENST00000373322 LRSAM1 Q6UWE0 E3 ubiquitin-protein ligase LRSAM1 chr9 GO:0048584 Not Cancer Driver No 86 0.119 240 30 0.125 1
LSM14A_ENST00000433627 LSM14A Q8ND56 Protein LSM14 homolog A chr19 GO:0048584 Census Yes 67 0.145 408 63 0.154 0
LTA LTA P01374 Lymphotoxin-alpha chr6 GO:0048584 Not Cancer Driver No 37 0.18 20 5 0.25 0
LTF LTF P02788 Lactotransferrin chr3 GO:0048584 Not Cancer Driver No 131 0.185 21 4 0.19 0
LY86 LY86 O95711 Lymphocyte antigen 86 chr6 GO:0048584 Not Cancer Driver No 29 0.179 0 0 0.0 0
LY96 LY96 Q9Y6Y9 Lymphocyte antigen 96 chr8 GO:0048584 Not Cancer Driver No 37 0.231 0 0 0.0 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0048584 Census Yes 95 0.186 84 12 0.143 0
MAD1L1_ENST00000399654 MAD1L1 Q9Y6D9 Mitotic spindle assembly checkpoint protein MAD1 chr7 GO:0048584 Not Cancer Driver No 117 0.163 526 77 0.146 0
MAD2L1 MAD2L1 Q13257 Mitotic spindle assembly checkpoint protein MAD2A chr4 GO:0048584 Not Cancer Driver No 26 0.127 12 1 0.083 0
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 GO:0048584 Not Cancer Driver No 22 0.104 0 0 0.0 1
MAL MAL P21145 Myelin and lymphocyte protein chr2 GO:0048584 Not Cancer Driver No 21 0.137 0 0 0.0 0
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:0048584 Census, Compendium Yes 75 0.091 139 12 0.086 1
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0048584 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K10 MAP3K10 Q02779 Mitogen-activated protein kinase kinase kinase 10 chr19 GO:0048584 Not Cancer Driver No 112 0.117 589 62 0.105 0
MAP3K11 MAP3K11 Q16584 Mitogen-activated protein kinase kinase kinase 11 chr11 GO:0048584 Not Cancer Driver No 97 0.115 466 54 0.116 0
MAP3K12_ENST00000267079 MAP3K12 Q12852 Mitogen-activated protein kinase kinase kinase 12 chr12 GO:0048584 Not Cancer Driver No 120 0.14 481 64 0.133 0
MAP3K13_ENST00000424227 MAP3K13 O43283 Mitogen-activated protein kinase kinase kinase 13 chr3 GO:0048584 Census Yes 157 0.163 593 91 0.153 0
MAP3K20 MAP3K20 Q9NYL2 Mitogen-activated protein kinase kinase kinase 20 chr2 GO:0048584 Not Cancer Driver No 101 0.126 294 41 0.139 1
MAP3K3_ENST00000361733 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 GO:0048584 Not Cancer Driver No 74 0.118 355 44 0.124 0
MAP3K4 MAP3K4 Q9Y6R4 Mitogen-activated protein kinase kinase kinase 4 chr6 GO:0048584 Not Cancer Driver No 261 0.162 520 86 0.165 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:0048584 Not Cancer Driver No 197 0.143 242 29 0.12 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0048584 Not Cancer Driver No 104 0.172 333 66 0.198 6
MAP4K2 MAP4K2 Q12851 Mitogen-activated protein kinase kinase kinase kinase 2 chr11 GO:0048584 Not Cancer Driver No 78 0.095 243 23 0.095 0
MAP4K4_ENST00000347699 MAP4K4 O95819 Mitogen-activated protein kinase kinase kinase kinase 4 chr2 GO:0048584 Not Cancer Driver No 143 0.115 649 55 0.085 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0048584 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0048584 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAPRE2 MAPRE2 Q15555 Microtubule-associated protein RP/EB family member 2 chr18 GO:0048584 Not Cancer Driver No 50 0.153 176 28 0.159 3
MASP1_ENST00000337774 MASP1 P48740 Mannan-binding lectin serine protease 1 chr3 GO:0048584 Not Cancer Driver No 142 0.203 72 14 0.194 0
MASP2 MASP2 O00187 Mannan-binding lectin serine protease 2 chr1 GO:0048584 Not Cancer Driver No 99 0.144 58 11 0.19 2
MAVS MAVS Q7Z434 Mitochondrial antiviral-signaling protein chr20 GO:0048584 Not Cancer Driver No 70 0.13 411 58 0.141 0
MAZ_ENST00000322945 MAZ P56270 Myc-associated zinc finger protein chr16 GO:0048584 Not Cancer Driver No 46 0.096 249 22 0.088 0
MBD5 MBD5 Q9P267 Methyl-CpG-binding domain protein 5 chr2 GO:0048584 Not Cancer Driver No 254 0.17 1289 219 0.17 0
MBL2 MBL2 P11226 Mannose-binding protein C chr10 GO:0048584 Not Cancer Driver No 63 0.254 122 32 0.262 0
MBTD1_ENST00000415868 MBTD1 Q05BQ5 MBT domain-containing protein 1 chr17 GO:0048584 Not Cancer Driver No 66 0.105 119 8 0.067 0
MC1R_ENST00000639847 MC1R Q01726 Melanocyte-stimulating hormone receptor chr16 GO:0048584 Not Cancer Driver No 39 0.123 0 0 0.0 5
MCF2L_ENST00000375608 MCF2L O15068 Guanine nucleotide exchange factor DBS chr13 GO:0048584 Not Cancer Driver No 173 0.152 410 54 0.132 0
MCL1 MCL1 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 chr1 GO:0048584 Not Cancer Driver No 30 0.086 203 21 0.103 0
MCU MCU Q8NE86 Calcium uniporter protein, mitochondrial chr10 GO:0048584 Not Cancer Driver No 41 0.117 13 0 0.0 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0048584 Not Cancer Driver No 15 0.105 20 2 0.1 0
MEAF6_ENST00000296214 MEAF6 Q9HAF1 Chromatin modification-related protein MEAF6 chr1 GO:0048584 Not Cancer Driver No 22 0.115 171 21 0.123 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0048584 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0048584 Not Cancer Driver No 92 0.195 408 81 0.199 0
MEGF8 MEGF8 Q7Z7M0 Multiple epidermal growth factor-like domains protein 8 chr19 GO:0048584 Not Cancer Driver No 363 0.128 476 59 0.124 3
MEN1 MEN1 O00255 Menin chr11 GO:0048584 Census, Compendium Yes 73 0.119 228 15 0.066 90
MESP1 MESP1 Q9BRJ9 Mesoderm posterior protein 1 chr15 GO:0048584 Not Cancer Driver No 8 0.03 247 7 0.028 0
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 GO:0048584 Census, Compendium Yes 226 0.163 62 15 0.242 19
MFAP4_ENST00000299610 MFAP4 P55083 Microfibril-associated glycoprotein 4 chr17 GO:0048584 Not Cancer Driver No 35 0.137 0 0 0.0 0
MFHAS1 MFHAS1 Q9Y4C4 Malignant fibrous histiocytoma-amplified sequence 1 chr8 GO:0048584 Not Cancer Driver No 95 0.09 98 9 0.092 0
MFNG MFNG O00587 Beta-1,3-N-acetylglucosaminyltransferase manic fringe chr22 GO:0048584 Not Cancer Driver No 37 0.115 29 4 0.138 0
MIF MIF P14174 Macrophage migration inhibitory factor chr22 GO:0048584 Not Cancer Driver No 4 0.035 0 0 0.0 0
MINK1 MINK1 Q8N4C8 Misshapen-like kinase 1 chr17 GO:0048584 Not Cancer Driver No 113 0.085 740 56 0.076 0
MIOS_ENST00000405785 MIOS Q9NXC5 GATOR complex protein MIOS chr7 GO:0048584 Not Cancer Driver No 98 0.112 72 4 0.056 0
MLH1 MLH1 P40692 DNA mismatch repair protein Mlh1 chr3 GO:0048584 Census Yes 92 0.122 208 22 0.106 85
MLLT3 MLLT3 P42568 Protein AF-9 chr9 GO:0048584 Census, Compendium Yes 69 0.121 414 58 0.14 0
MMP12 MMP12 P39900 Macrophage metalloelastase chr11 GO:0048584 Not Cancer Driver No 100 0.213 29 5 0.172 0
MMP8 MMP8 P22894 Neutrophil collagenase chr11 GO:0048584 Not Cancer Driver No 73 0.156 115 19 0.165 0
MMP9 MMP9 P14780 Matrix metalloproteinase-9 chr20 GO:0048584 Not Cancer Driver No 129 0.182 124 26 0.21 0
MMS19 MMS19 Q96T76 MMS19 nucleotide excision repair protein homolog chr10 GO:0048584 Not Cancer Driver No 73 0.071 11 0 0.0 0
MN1 MN1 Q10571 Transcriptional activator MN1 chr22 GO:0048584 Census Yes 148 0.112 1283 140 0.109 0
MORF4L1 MORF4L1 Q9UBU8 Mortality factor 4-like protein 1 chr15 GO:0048584 Not Cancer Driver No 43 0.119 163 17 0.104 0
MORF4L2_ENST00000433176 MORF4L2 Q15014 Mortality factor 4-like protein 2 chrX GO:0048584 Not Cancer Driver No 44 0.153 136 21 0.154 0
MOSPD2 MOSPD2 Q8NHP6 Motile sperm domain-containing protein 2 chrX GO:0048584 Not Cancer Driver No 58 0.112 143 16 0.112 0
MR1 MR1 Q95460 Major histocompatibility complex class I-related gene protein chr1 GO:0048584 Not Cancer Driver No 60 0.176 33 7 0.212 0
MRAP MRAP Q8TCY5 Melanocortin-2 receptor accessory protein chr21 GO:0048584 Not Cancer Driver No 29 0.169 63 7 0.111 0
MRAP2 MRAP2 Q96G30 Melanocortin-2 receptor accessory protein 2 chr6 GO:0048584 Not Cancer Driver No 55 0.268 75 17 0.227 0
MRGBP MRGBP Q9NV56 MRG/MORF4L-binding protein chr20 GO:0048584 Not Cancer Driver No 27 0.132 147 23 0.156 0
MRNIP MRNIP Q6NTE8 MRN complex-interacting protein chr5 GO:0048584 Not Cancer Driver No 44 0.128 268 35 0.131 0
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:0048584 Census Yes 92 0.099 37 4 0.108 70
MSTN MSTN O14793 Growth/differentiation factor 8 chr2 GO:0048584 Not Cancer Driver No 68 0.181 64 11 0.172 0
MSX1 MSX1 P28360 Homeobox protein MSX-1 chr4 GO:0048584 Not Cancer Driver No 39 0.129 197 16 0.081 7
MSX2 MSX2 P35548 Homeobox protein MSX-2 chr5 GO:0048584 Not Cancer Driver No 27 0.101 168 14 0.083 4
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0048584 Not Cancer Driver No 7 0.103 0 0 0.0 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0048584 Census, Compendium Yes 379 0.149 296 37 0.125 18
MYB_ENST00000367814 MYB P10242 Transcriptional activator Myb chr6 GO:0048584 Census Yes 82 0.128 528 69 0.131 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0048584 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYDGF MYDGF Q969H8 Myeloid-derived growth factor chr19 GO:0048584 Not Cancer Driver No 23 0.133 26 4 0.154 0
MYMK MYMK A6NI61 Protein myomaker chr9 GO:0048584 Not Cancer Driver No 32 0.145 0 0 0.0 3
MYO1C MYO1C O00159 Unconventional myosin-Ic chr17 GO:0048584 Not Cancer Driver No 110 0.103 66 11 0.167 0
MYO1G MYO1G B0I1T2 Unconventional myosin-Ig chr7 GO:0048584 Not Cancer Driver No 125 0.123 117 12 0.103 0
MYOC MYOC Q99972 Myocilin chr1 GO:0048584 Not Cancer Driver No 92 0.183 196 43 0.219 58
MYOCD_ENST00000343344 MYOCD Q8IZQ8 Myocardin chr17 GO:0048584 Not Cancer Driver No 284 0.303 853 263 0.308 0
MYOG MYOG P15173 Myogenin chr1 GO:0048584 Not Cancer Driver No 36 0.161 132 20 0.152 0
MYORG MYORG Q6NSJ0 Myogenesis-regulating glycosidase chr9 GO:0048584 Not Cancer Driver No 88 0.123 60 3 0.05 2
NACC2_ENST00000371753 NACC2 Q96BF6 Nucleus accumbens-associated protein 2 chr9 GO:0048584 Not Cancer Driver No 24 0.041 238 10 0.042 0
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 GO:0048584 Not Cancer Driver No 37 0.095 181 12 0.066 1
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 GO:0048584 Not Cancer Driver No 48 0.127 111 17 0.153 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 GO:0048584 Not Cancer Driver No 89 0.234 88 19 0.216 0
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:0048584 Not Cancer Driver No 247 0.219 51 10 0.196 4
NDC80 NDC80 O14777 Kinetochore protein NDC80 homolog chr18 GO:0048584 Not Cancer Driver No 80 0.125 313 45 0.144 0
NDEL1 NDEL1 Q9GZM8 Nuclear distribution protein nudE-like 1 chr17 GO:0048584 Not Cancer Driver No 32 0.093 202 16 0.079 0
NDST1 NDST1 P52848 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 chr5 GO:0048584 Not Cancer Driver No 117 0.133 22 1 0.045 4
NECAB2 NECAB2 Q7Z6G3 N-terminal EF-hand calcium-binding protein 2 chr16 GO:0048584 Not Cancer Driver No 46 0.119 122 9 0.074 0
NECTIN2 NECTIN2 Q92692 Nectin-2 chr19 GO:0048584 Not Cancer Driver No 63 0.117 296 29 0.098 0
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 GO:0048584 Not Cancer Driver No 150 0.114 711 79 0.111 0
NEO1_ENST00000261908 NEO1 Q92859 Neogenin chr15 GO:0048584 Not Cancer Driver No 182 0.125 706 96 0.136 0
NEPRO NEPRO Q6NW34 Nucleolus and neural progenitor protein chr3 GO:0048584 Not Cancer Driver No 62 0.109 147 28 0.19 0
NET1 NET1 Q7Z628 Neuroepithelial cell-transforming gene 1 protein chr10 GO:0048584 Not Cancer Driver No 60 0.101 294 37 0.126 0
NETO1 NETO1 Q8TDF5 Neuropilin and tolloid-like protein 1 chr18 GO:0048584 Not Cancer Driver No 186 0.349 103 33 0.32 0
NEURL1 NEURL1 O76050 E3 ubiquitin-protein ligase NEURL1 chr10 GO:0048584 Not Cancer Driver No 62 0.108 153 11 0.072 0
NEUROD2 NEUROD2 Q15784 Neurogenic differentiation factor 2 chr17 GO:0048584 Not Cancer Driver No 26 0.068 210 14 0.067 2
NF1 NF1 P21359 Neurofibromin chr17 GO:0048584 Census, Compendium Yes 375 0.132 406 47 0.116 85
NFAM1 NFAM1 Q8NET5 NFAT activation molecule 1 chr22 GO:0048584 Not Cancer Driver No 30 0.111 116 18 0.155 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0048584 Census, Compendium Yes 228 0.377 402 62 0.154 4
NFKBID NFKBID Q8NI38 NF-kappa-B inhibitor delta chr19 GO:0048584 Not Cancer Driver No 47 0.15 124 20 0.161 0
NFKBIZ NFKBIZ Q9BYH8 NF-kappa-B inhibitor zeta chr3 GO:0048584 Not Cancer Driver No 96 0.134 443 53 0.12 0
NINJ1 NINJ1 Q92982 Ninjurin-1 chr9 GO:0048584 Not Cancer Driver No 17 0.112 29 0 0.0 0
NKD1 NKD1 Q969G9 Protein naked cuticle homolog 1 chr16 GO:0048584 Not Cancer Driver No 72 0.153 436 67 0.154 0
NKX3-1 NKX3-1 Q99801 Homeobox protein Nkx-3.1 chr8 GO:0048584 Not Cancer Driver No 35 0.15 171 16 0.094 0
NLGN1_ENST00000361589 NLGN1 Q8N2Q7 Neuroligin-1 chr3 GO:0048584 Not Cancer Driver No 214 0.248 248 61 0.246 4
NLGN2 NLGN2 Q8NFZ4 Neuroligin-2 chr17 GO:0048584 Not Cancer Driver No 91 0.109 300 19 0.063 0
NLGN3 NLGN3 Q9NZ94 Neuroligin-3 chrX GO:0048584 Not Cancer Driver No 158 0.186 257 54 0.21 2
NLRC5_ENST00000436936 NLRC5 Q86WI3 Protein NLRC5 chr16 GO:0048584 Not Cancer Driver No 262 0.14 114 19 0.167 0
NLRP10 NLRP10 Q86W26 NACHT, LRR and PYD domains-containing protein 10 chr11 GO:0048584 Not Cancer Driver No 201 0.307 96 34 0.354 0
NLRP3_ENST00000391828 NLRP3 Q96P20 NACHT, LRR and PYD domains-containing protein 3 chr1 GO:0048584 Not Cancer Driver No 339 0.327 64 33 0.516 37
NOD1 NOD1 Q9Y239 Nucleotide-binding oligomerization domain-containing protein 1 chr7 GO:0048584 Not Cancer Driver No 130 0.136 38 7 0.184 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0048584 Not Cancer Driver No 169 0.163 40 4 0.1 15
NODAL NODAL Q96S42 Nodal homolog chr10 GO:0048584 Not Cancer Driver No 40 0.115 34 8 0.235 4
NOS1AP NOS1AP O75052 Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein chr1 GO:0048584 Not Cancer Driver No 94 0.186 255 53 0.208 1
NOS3 NOS3 P29474 Nitric oxide synthase, endothelial chr7 GO:0048584 Not Cancer Driver No 168 0.14 347 38 0.11 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0048584 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0048584 Census, Compendium Yes 282 0.114 630 77 0.122 1
NOTCH2NLA NOTCH2NLA Q7Z3S9 Notch homolog 2 N-terminal-like protein A chr1 GO:0048584 Not Cancer Driver No 68 0.288 17 2 0.118 0
NOX1 NOX1 Q9Y5S8 NADPH oxidase 1 chrX GO:0048584 Not Cancer Driver No 101 0.179 18 8 0.444 0
NPAS2 NPAS2 Q99743 Neuronal PAS domain-containing protein 2 chr2 GO:0048584 Not Cancer Driver No 114 0.138 465 65 0.14 0
NPNT_ENST00000379987 NPNT Q6UXI9 Nephronectin chr4 GO:0048584 Not Cancer Driver No 90 0.159 218 33 0.151 0
NPPC NPPC P23582 C-type natriuretic peptide chr2 GO:0048584 Not Cancer Driver No 10 0.079 82 6 0.073 0
NPR1 NPR1 P16066 Atrial natriuretic peptide receptor 1 chr1 GO:0048584 Not Cancer Driver No 141 0.133 78 16 0.205 0
NPR2 NPR2 P20594 Atrial natriuretic peptide receptor 2 chr9 GO:0048584 Not Cancer Driver No 144 0.138 89 18 0.202 20
NPTN NPTN Q9Y639 Neuroplastin chr15 GO:0048584 Not Cancer Driver No 47 0.118 118 9 0.076 0
NPY5R_ENST00000506953 NPY5R Q15761 Neuropeptide Y receptor type 5 chr4 GO:0048584 Not Cancer Driver No 144 0.324 44 16 0.364 0
NPY_ENST00000405982 NPY P01303 Pro-neuropeptide Y chr7 GO:0048584 Not Cancer Driver No 29 0.299 43 19 0.442 0
NR1H3_ENST00000467728 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 GO:0048584 Not Cancer Driver No 56 0.125 146 13 0.089 0
NR1H4 NR1H4 Q96RI1 Bile acid receptor chr12 GO:0048584 Not Cancer Driver No 111 0.228 78 18 0.231 0
NR2C1 NR2C1 P13056 Nuclear receptor subfamily 2 group C member 1 chr12 GO:0048584 Not Cancer Driver No 65 0.108 156 13 0.083 0
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:0048584 Census Yes 83 0.133 298 37 0.124 0
NRG1_ENST00000405005 NRG1 Q02297 Pro-neuregulin-1, membrane-bound isoform chr8 GO:0048584 Census, Compendium Yes 159 0.248 528 132 0.25 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0048584 Compendium Yes 146 0.158 211 31 0.147 0
NRXN1_ENST00000406316 NRXN1 Q9ULB1 Neurexin-1 chr2 GO:0048584 Not Cancer Driver No 593 0.401 301 110 0.365 0
NSD2_ENST00000382892 NSD2 O96028 Histone-lysine N-methyltransferase NSD2 chr4 GO:0048584 Census, Compendium Yes 191 0.14 552 76 0.138 0
NTF3_ENST00000331010 NTF3 P20783 Neurotrophin-3 chr12 GO:0048584 Not Cancer Driver No 52 0.202 99 21 0.212 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0048584 Census, Compendium Yes 168 0.211 57 8 0.14 25
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:0048584 Not Cancer Driver No 155 0.189 117 18 0.154 1
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0048584 Census, Compendium Yes 249 0.297 57 21 0.368 0
NUCKS1 NUCKS1 Q9H1E3 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 chr1 GO:0048584 Not Cancer Driver No 30 0.123 243 30 0.123 0
NUMA1 NUMA1 Q14980 Nuclear mitotic apparatus protein 1 chr11 GO:0048584 Census, Compendium Yes 234 0.111 1864 203 0.109 0
NUP62 NUP62 P37198 Nuclear pore glycoprotein p62 chr19 GO:0048584 Not Cancer Driver No 76 0.146 377 56 0.149 1
NUP93 NUP93 Q8N1F7 Nuclear pore complex protein Nup93 chr16 GO:0048584 Not Cancer Driver No 97 0.118 158 23 0.146 3
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 GO:0048584 Not Cancer Driver No 10 0.122 82 10 0.122 0
OASL OASL Q15646 2'-5'-oligoadenylate synthase-like protein chr12 GO:0048584 Not Cancer Driver No 76 0.148 8 4 0.5 0
OOEP OOEP A6NGQ2 Oocyte-expressed protein homolog chr6 GO:0048584 Not Cancer Driver No 46 0.309 48 14 0.292 0
OPRK1_ENST00000520287 OPRK1 P41145 Kappa-type opioid receptor chr8 GO:0048584 Not Cancer Driver No 117 0.308 18 5 0.278 0
OPRM1_ENST00000330432 OPRM1 P35372 Mu-type opioid receptor chr6 GO:0048584 Not Cancer Driver No 107 0.268 58 27 0.466 0
OPTN_ENST00000263036 OPTN Q96CV9 Optineurin chr10 GO:0048584 Not Cancer Driver No 58 0.101 470 51 0.109 6
OR51E2_ENST00000641638 OR51E2 Q9H255 Olfactory receptor 51E2 chr11 GO:0048584 Not Cancer Driver No 108 0.338 0 0 0.0 0
OSBPL8 OSBPL8 Q9BZF1 Oxysterol-binding protein-related protein 8 chr12 GO:0048584 Not Cancer Driver No 105 0.118 401 37 0.092 0
OSM OSM P13725 Oncostatin-M chr22 GO:0048584 Not Cancer Driver No 43 0.171 114 24 0.211 0
OSMR OSMR Q99650 Oncostatin-M-specific receptor subunit beta chr5 GO:0048584 Not Cancer Driver No 167 0.171 145 22 0.152 5
OTUD5 OTUD5 Q96G74 OTU domain-containing protein 5 chrX GO:0048584 Not Cancer Driver No 55 0.096 430 39 0.091 4
OXSR1 OXSR1 O95747 Serine/threonine-protein kinase OSR1 chr3 GO:0048584 Not Cancer Driver No 69 0.131 208 29 0.139 0
P2RX2_ENST00000643471 P2RX2 Q9UBL9 P2X purinoceptor 2 chr12 GO:0048584 Not Cancer Driver No 62 0.132 104 13 0.125 2
P2RX3 P2RX3 P56373 P2X purinoceptor 3 chr11 GO:0048584 Not Cancer Driver No 85 0.214 15 6 0.4 0
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 GO:0048584 Not Cancer Driver No 36 0.093 0 0 0.0 0
P2RX5 P2RX5 Q93086 P2X purinoceptor 5 chr17 GO:0048584 Not Cancer Driver No 58 0.137 73 14 0.192 0
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0048584 Not Cancer Driver No 51 0.086 14 2 0.143 0
P2RY10 P2RY10 O00398 Putative P2Y purinoceptor 10 chrX GO:0048584 Not Cancer Driver No 113 0.333 0 0 0.0 0
P2RY6_ENST00000540342 P2RY6 Q15077 P2Y purinoceptor 6 chr11 GO:0048584 Not Cancer Driver No 50 0.152 10 5 0.5 0
P2RY8 P2RY8 Q86VZ1 P2Y purinoceptor 8 chrX GO:0048584 Census, Compendium Yes 126 0.351 23 5 0.217 0
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:0048584 Not Cancer Driver No 42 0.102 82 11 0.134 7
PAGR1 PAGR1 Q9BTK6 PAXIP1-associated glutamate-rich protein 1 chr16 GO:0048584 Not Cancer Driver No 16 0.063 254 16 0.063 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0048584 Not Cancer Driver No 57 0.105 299 30 0.1 2
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 GO:0048584 Compendium Yes 89 0.17 242 49 0.202 0
PAK3_ENST00000262836 PAK3 O75914 Serine/threonine-protein kinase PAK 3 chrX GO:0048584 Not Cancer Driver No 127 0.227 286 64 0.224 2
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0048584 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0048584 Not Cancer Driver No 119 0.117 320 34 0.106 0
PARP14 PARP14 Q460N5 Protein mono-ADP-ribosyltransferase PARP14 chr3 GO:0048584 Not Cancer Driver No 221 0.123 301 57 0.189 0
PARP3_ENST00000431474 PARP3 Q9Y6F1 Protein mono-ADP-ribosyltransferase PARP3 chr3 GO:0048584 Not Cancer Driver No 70 0.131 269 38 0.141 0
PARP9 PARP9 Q8IXQ6 Protein mono-ADP-ribosyltransferase PARP9 chr3 GO:0048584 Not Cancer Driver No 110 0.129 45 3 0.067 0
PAWR PAWR Q96IZ0 PRKC apoptosis WT1 regulator protein chr12 GO:0048584 Not Cancer Driver No 35 0.103 327 33 0.101 0
PAXIP1 PAXIP1 Q6ZW49 PAX-interacting protein 1 chr7 GO:0048584 Not Cancer Driver No 120 0.112 461 39 0.085 0
PCID2_ENST00000375479 PCID2 Q5JVF3 PCI domain-containing protein 2 chr13 GO:0048584 Not Cancer Driver No 46 0.115 13 5 0.385 0
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0048584 Not Cancer Driver No 142 0.228 110 28 0.255 1
PDCD10_ENST00000473645 PDCD10 Q9BUL8 Programmed cell death protein 10 chr3 GO:0048584 Not Cancer Driver No 32 0.151 25 4 0.16 0
PDCL PDCL Q13371 Phosducin-like protein chr9 GO:0048584 Not Cancer Driver No 33 0.11 146 13 0.089 0
PDE6G PDE6G P18545 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma chr17 GO:0048584 Not Cancer Driver No 15 0.172 58 11 0.19 0
PDE6H PDE6H Q13956 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma chr12 GO:0048584 Not Cancer Driver No 15 0.181 59 14 0.237 0
PDGFA PDGFA P04085 Platelet-derived growth factor subunit A chr7 GO:0048584 Not Cancer Driver No 31 0.147 75 10 0.133 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0048584 Census Yes 37 0.154 99 22 0.222 2
PDGFC PDGFC Q9NRA1 Platelet-derived growth factor C chr4 GO:0048584 Not Cancer Driver No 86 0.249 53 12 0.226 0
PDGFD PDGFD Q9GZP0 Platelet-derived growth factor D chr11 GO:0048584 Not Cancer Driver No 85 0.23 37 13 0.351 0
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 GO:0048584 Census, Compendium Yes 290 0.266 173 45 0.26 2
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0048584 Census, Compendium Yes 164 0.148 231 44 0.19 7
PEA15_ENST00000360472 PEA15 Q15121 Astrocytic phosphoprotein PEA-15 chr1 GO:0048584 Not Cancer Driver No 12 0.092 35 5 0.143 0
PELI1 PELI1 Q96FA3 E3 ubiquitin-protein ligase pellino homolog 1 chr2 GO:0048584 Not Cancer Driver No 47 0.112 167 17 0.102 0
PELO PELO Q9BRX2 Protein pelota homolog chr5 GO:0048584 Not Cancer Driver No 38 0.099 67 10 0.149 0
PENK_ENST00000451791 PENK P01210 Proenkephalin-A chr8 GO:0048584 Not Cancer Driver No 109 0.408 142 62 0.437 0
PGC PGC P20142 Gastricsin chr6 GO:0048584 Not Cancer Driver No 60 0.155 20 1 0.05 0
PGF_ENST00000405431 PGF P49763 Placenta growth factor chr14 GO:0048584 Not Cancer Driver No 30 0.136 72 10 0.139 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:0048584 Not Cancer Driver No 37 0.136 4 1 0.25 0
PHIP PHIP Q8WWQ0 PH-interacting protein chr6 GO:0048584 Not Cancer Driver No 239 0.131 835 110 0.132 0
PIAS4 PIAS4 Q8N2W9 E3 SUMO-protein ligase PIAS4 chr19 GO:0048584 Not Cancer Driver No 58 0.114 142 23 0.162 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 GO:0048584 Not Cancer Driver No 30 0.103 157 13 0.083 0
PIK3AP1 PIK3AP1 Q6ZUJ8 Phosphoinositide 3-kinase adapter protein 1 chr10 GO:0048584 Not Cancer Driver No 141 0.175 406 81 0.2 0
PIK3CB_ENST00000477593 PIK3CB P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 GO:0048584 Census, Compendium Yes 150 0.14 42 4 0.095 0
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 GO:0048584 Not Cancer Driver No 318 0.289 121 39 0.322 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0048584 Census, Compendium Yes 154 0.213 268 61 0.228 2
PIP4P1_ENST00000250489 PIP4P1 Q86T03 Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase chr14 GO:0048584 Not Cancer Driver No 36 0.13 78 4 0.051 0
PJA2 PJA2 O43164 E3 ubiquitin-protein ligase Praja-2 chr5 GO:0048584 Not Cancer Driver No 80 0.113 598 66 0.11 0
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0048584 Not Cancer Driver No 113 0.117 375 35 0.093 10
PLA2G3 PLA2G3 Q9NZ20 Group 3 secretory phospholipase A2 chr22 GO:0048584 Not Cancer Driver No 115 0.226 175 39 0.223 0
PLA2G4A PLA2G4A P47712 Cytosolic phospholipase A2 chr1 GO:0048584 Not Cancer Driver No 149 0.199 129 28 0.217 1
PLA2G5 PLA2G5 P39877 Phospholipase A2 group V chr1 GO:0048584 Not Cancer Driver No 24 0.174 0 0 0.0 2
PLA2G6 PLA2G6 O60733 85/88 kDa calcium-independent phospholipase A2 chr22 GO:0048584 Not Cancer Driver No 108 0.134 148 23 0.155 11
PLA2G7 PLA2G7 Q13093 Platelet-activating factor acetylhydrolase chr6 GO:0048584 Not Cancer Driver No 70 0.159 27 7 0.259 2
PLA2R1 PLA2R1 Q13018 Secretory phospholipase A2 receptor chr2 GO:0048584 Not Cancer Driver No 202 0.138 39 2 0.051 0
PLAGL2 PLAGL2 Q9UPG8 Zinc finger protein PLAGL2 chr20 GO:0048584 Not Cancer Driver No 62 0.125 204 29 0.142 0
PLAUR PLAUR Q03405 Urokinase plasminogen activator surface receptor chr19 GO:0048584 Not Cancer Driver No 49 0.146 18 5 0.278 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0048584 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLD2 PLD2 O14939 Phospholipase D2 chr17 GO:0048584 Not Cancer Driver No 107 0.115 97 8 0.082 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 GO:0048584 Not Cancer Driver No 136 0.175 687 128 0.186 0
PLEKHF1 PLEKHF1 Q96S99 Pleckstrin homology domain-containing family F member 1 chr19 GO:0048584 Not Cancer Driver No 30 0.108 65 10 0.154 0
PLG PLG P00747 Plasminogen chr6 GO:0048584 Not Cancer Driver No 242 0.299 230 64 0.278 9
PLPP4 PLPP4 Q5VZY2 Phospholipid phosphatase 4 chr10 GO:0048584 Not Cancer Driver No 59 0.218 14 1 0.071 0
PLXNB1_ENST00000296440 PLXNB1 O43157 Plexin-B1 chr3 GO:0048584 Not Cancer Driver No 228 0.107 684 67 0.098 0
PMAIP1 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 GO:0048584 Not Cancer Driver No 2 0.037 23 1 0.043 0
PML PML P29590 Protein PML chr15 GO:0048584 Census, Compendium Yes 112 0.127 312 34 0.109 0
PNKP PNKP Q96T60 Bifunctional polynucleotide phosphatase/kinase chr19 GO:0048584 Not Cancer Driver No 53 0.102 177 23 0.13 4
POGLUT1 POGLUT1 Q8NBL1 Protein O-glucosyltransferase 1 chr3 GO:0048584 Not Cancer Driver No 57 0.145 0 0 0.0 3
POGZ POGZ Q7Z3K3 Pogo transposable element with ZNF domain chr1 GO:0048584 Not Cancer Driver No 157 0.111 746 78 0.105 0
POMC POMC P01189 Pro-opiomelanocortin chr2 GO:0048584 Not Cancer Driver No 50 0.187 198 38 0.192 0
POR POR P16435 NADPH--cytochrome P450 reductase chr7 GO:0048584 Not Cancer Driver No 62 0.092 93 4 0.043 9
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 GO:0048584 Not Cancer Driver No 72 0.163 69 7 0.101 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0048584 Census Yes 72 0.143 44 4 0.091 3
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 GO:0048584 Not Cancer Driver No 38 0.115 27 6 0.222 0
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 GO:0048584 Census, Compendium Yes 179 0.304 0 0 0.0 4
PPP2R1B_ENST00000527614 PPP2R1B P30154 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform chr11 GO:0048584 Not Cancer Driver No 72 0.12 17 1 0.059 0
PPP2R5B PPP2R5B Q15173 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform chr11 GO:0048584 Not Cancer Driver No 79 0.159 119 9 0.076 0
PPP3CA PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 GO:0048584 Compendium Yes 85 0.163 140 27 0.193 7
PRAG1_ENST00000622241 PRAG1 Q86YV5 Inactive tyrosine-protein kinase PRAG1 chr8 GO:0048584 Not Cancer Driver No 193 0.137 988 150 0.152 0
PRDX2 PRDX2 P32119 Peroxiredoxin-2 chr19 GO:0048584 Not Cancer Driver No 24 0.121 30 4 0.133 0
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 GO:0048584 Not Cancer Driver No 94 0.14 154 22 0.143 0
PRKCB_ENST00000321728 PRKCB P05771 Protein kinase C beta type chr16 GO:0048584 Census, Compendium Yes 205 0.306 148 40 0.27 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0048584 Compendium Yes 79 0.117 43 9 0.209 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 GO:0048584 Not Cancer Driver No 107 0.145 170 26 0.153 0
PRKCG PRKCG P05129 Protein kinase C gamma type chr19 GO:0048584 Not Cancer Driver No 172 0.247 151 43 0.285 5
PRKCH PRKCH P24723 Protein kinase C eta type chr14 GO:0048584 Not Cancer Driver No 89 0.13 92 13 0.141 0
PRKCI PRKCI P41743 Protein kinase C iota type chr3 GO:0048584 Not Cancer Driver No 110 0.185 120 16 0.133 0
PRKCQ PRKCQ Q04759 Protein kinase C theta type chr10 GO:0048584 Not Cancer Driver No 147 0.208 28 9 0.321 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0048584 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 GO:0048584 Census Yes 201 0.22 189 33 0.175 2
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0048584 Compendium Yes 118 0.134 246 34 0.138 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0048584 Not Cancer Driver No 538 0.13 421 61 0.145 2
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0048584 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRKRA PRKRA O75569 Interferon-inducible double-stranded RNA-dependent protein kinase activator A chr2 GO:0048584 Not Cancer Driver No 41 0.131 104 12 0.115 1
PRMT1 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 GO:0048584 Not Cancer Driver No 50 0.135 18 1 0.056 0
PRMT5 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 GO:0048584 Not Cancer Driver No 83 0.13 72 6 0.083 0
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:0048584 Not Cancer Driver No 182 0.247 537 141 0.263 0
PRR5L PRR5L Q6MZQ0 Proline-rich protein 5-like chr11 GO:0048584 Not Cancer Driver No 57 0.155 108 12 0.111 0
PRR5_ENST00000336985 PRR5 P85299 Proline-rich protein 5 chr22 GO:0048584 Not Cancer Driver No 50 0.129 173 22 0.127 0
PRRX1 PRRX1 P54821 Paired mesoderm homeobox protein 1 chr1 GO:0048584 Census, Compendium Yes 69 0.282 205 49 0.239 1
PTAFR_ENST00000305392 PTAFR P25105 Platelet-activating factor receptor chr1 GO:0048584 Not Cancer Driver No 42 0.123 0 0 0.0 0
PTBP1_ENST00000349038 PTBP1 P26599 Polypyrimidine tract-binding protein 1 chr19 GO:0048584 Not Cancer Driver No 74 0.139 154 17 0.11 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0048584 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTGDR2 PTGDR2 Q9Y5Y4 Prostaglandin D2 receptor 2 chr11 GO:0048584 Not Cancer Driver No 23 0.058 39 0 0.0 0
PTGER3_ENST00000370931 PTGER3 P43115 Prostaglandin E2 receptor EP3 subtype chr1 GO:0048584 Not Cancer Driver No 79 0.203 17 2 0.118 0
PTGIS PTGIS Q16647 Prostacyclin synthase chr20 GO:0048584 Not Cancer Driver No 102 0.204 18 3 0.167 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0048584 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0048584 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:0048584 Not Cancer Driver No 134 0.127 425 55 0.129 0
PTK6 PTK6 Q13882 Protein-tyrosine kinase 6 chr20 GO:0048584 Census Yes 42 0.093 12 0 0.0 0
PTN PTN P21246 Pleiotrophin chr7 GO:0048584 Not Cancer Driver No 43 0.256 51 11 0.216 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:0048584 Not Cancer Driver No 49 0.113 140 25 0.179 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0048584 Census, Compendium Yes 129 0.218 260 38 0.146 60
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:0048584 Not Cancer Driver No 57 0.137 120 14 0.117 0
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0048584 Not Cancer Driver No 141 0.175 364 62 0.17 4
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:0048584 Census, Compendium Yes 73 0.123 192 25 0.13 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0048584 Census, Compendium Yes 315 0.241 462 107 0.232 0
PTPRJ PTPRJ Q12913 Receptor-type tyrosine-protein phosphatase eta chr11 GO:0048584 Not Cancer Driver No 184 0.138 401 61 0.152 0
PUM1_ENST00000257075 PUM1 Q14671 Pumilio homolog 1 chr1 GO:0048584 Not Cancer Driver No 150 0.126 640 77 0.12 3
PUM2_ENST00000403432 PUM2 Q8TB72 Pumilio homolog 2 chr2 GO:0048584 Not Cancer Driver No 132 0.124 575 83 0.144 0
PVR PVR P15151 Poliovirus receptor chr19 GO:0048584 Not Cancer Driver No 39 0.094 120 19 0.158 0
PYHIN1 PYHIN1 Q6K0P9 Pyrin and HIN domain-containing protein 1 chr1 GO:0048584 Not Cancer Driver No 174 0.354 291 99 0.34 0
RAB29 RAB29 O14966 Ras-related protein Rab-7L1 chr1 GO:0048584 Not Cancer Driver No 28 0.138 18 3 0.167 0
RAB34_ENST00000436730 RAB34 Q9BZG1 Ras-related protein Rab-34 chr17 GO:0048584 Not Cancer Driver No 41 0.158 1 0 0.0 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:0048584 Census, Compendium Yes 66 0.344 2 1 0.5 6
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 GO:0048584 Not Cancer Driver No 31 0.161 0 0 0.0 2
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:0048584 Not Cancer Driver No 34 0.107 13 0 0.0 0
RAD51AP1 RAD51AP1 Q96B01 RAD51-associated protein 1 chr12 GO:0048584 Not Cancer Driver No 46 0.131 335 43 0.128 0
RAD9A RAD9A Q99638 Cell cycle checkpoint control protein RAD9A chr11 GO:0048584 Not Cancer Driver No 34 0.087 135 7 0.052 0
RAET1G RAET1G Q6H3X3 UL-16 binding protein 5 chr6 GO:0048584 Not Cancer Driver No 41 0.123 62 10 0.161 0
RAMP3 RAMP3 O60896 Receptor activity-modifying protein 3 chr7 GO:0048584 Not Cancer Driver No 30 0.203 0 0 0.0 0
RAPGEF2 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 GO:0048584 Not Cancer Driver No 216 0.144 803 116 0.144 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0048584 Census, Compendium Yes 70 0.152 167 14 0.084 0
RARRES2 RARRES2 Q99969 Retinoic acid receptor responder protein 2 chr7 GO:0048584 Not Cancer Driver No 16 0.098 14 2 0.143 0
RBBP8_ENST00000327155 RBBP8 Q99708 DNA endonuclease RBBP8 chr18 GO:0048584 Not Cancer Driver No 99 0.11 750 76 0.101 1
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 GO:0048584 Not Cancer Driver No 49 0.098 151 19 0.126 2
RBPMS_ENST00000320203 RBPMS Q93062 RNA-binding protein with multiple splicing chr8 GO:0048584 Not Cancer Driver No 23 0.117 87 11 0.126 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:0048584 Compendium Yes 75 0.136 400 48 0.12 0
RELL1_ENST00000314117 RELL1 Q8IUW5 RELT-like protein 1 chr4 GO:0048584 Not Cancer Driver No 19 0.07 201 11 0.055 0
RELL2 RELL2 Q8NC24 RELT-like protein 2 chr5 GO:0048584 Not Cancer Driver No 39 0.129 259 37 0.143 0
RELN RELN P78509 Reelin chr7 GO:0048584 Not Cancer Driver No 761 0.22 107 19 0.178 7
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 GO:0048584 Census, Compendium Yes 208 0.187 105 12 0.114 139
RFNG RFNG Q9Y644 Beta-1,3-N-acetylglucosaminyltransferase radical fringe chr17 GO:0048584 Not Cancer Driver No 22 0.066 92 5 0.054 0
RGL2 RGL2 O15211 Ral guanine nucleotide dissociation stimulator-like 2 chr6 GO:0048584 Not Cancer Driver No 87 0.112 461 51 0.111 0
RGS4_ENST00000367909 RGS4 P49798 Regulator of G-protein signaling 4 chr1 GO:0048584 Not Cancer Driver No 68 0.332 5 4 0.8 0
RIF1 RIF1 Q5UIP0 Telomere-associated protein RIF1 chr2 GO:0048584 Not Cancer Driver No 287 0.116 1355 164 0.121 0
RIMS1 RIMS1 Q86UR5 Regulating synaptic membrane exocytosis protein 1 chr6 GO:0048584 Not Cancer Driver No 403 0.238 1315 306 0.233 1
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:0048584 Compendium Yes 82 0.122 277 39 0.141 4
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0048584 Not Cancer Driver No 63 0.117 143 20 0.14 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:0048584 Not Cancer Driver No 66 0.127 295 39 0.132 0
RIPOR2_ENST00000259698 RIPOR2 Q9Y4F9 Rho family-interacting cell polarization regulator 2 chr6 GO:0048584 Not Cancer Driver No 131 0.123 421 76 0.181 0
RNF111_ENST00000557998 RNF111 Q6ZNA4 E3 ubiquitin-protein ligase Arkadia chr15 GO:0048584 Not Cancer Driver No 111 0.112 855 96 0.112 0
RNF165 RNF165 Q6ZSG1 E3 ubiquitin-protein ligase RNF165 chr18 GO:0048584 Not Cancer Driver No 62 0.179 225 40 0.178 0
RNF183_ENST00000297894 RNF183 Q96D59 E3 ubiquitin-protein ligase RNF183 chr9 GO:0048584 Not Cancer Driver No 22 0.115 29 1 0.034 0
RNF185 RNF185 Q96GF1 E3 ubiquitin-protein ligase RNF185 chr22 GO:0048584 Not Cancer Driver No 25 0.13 82 15 0.183 0
RNF31 RNF31 Q96EP0 E3 ubiquitin-protein ligase RNF31 chr14 GO:0048584 Not Cancer Driver No 142 0.132 319 45 0.141 0
RNFT1 RNFT1 Q5M7Z0 E3 ubiquitin-protein ligase RNFT1 chr17 GO:0048584 Not Cancer Driver No 37 0.085 117 18 0.154 0
RNFT2_ENST00000392549 RNFT2 Q96EX2 RING finger and transmembrane domain-containing protein 2 chr12 GO:0048584 Not Cancer Driver No 37 0.083 129 10 0.078 0
ROBO1 ROBO1 Q9Y6N7 Roundabout homolog 1 chr3 GO:0048584 Not Cancer Driver No 353 0.214 1122 234 0.209 0
ROBO2_ENST00000461745 ROBO2 Q9HCK4 Roundabout homolog 2 chr3 GO:0048584 Census Yes 407 0.295 874 259 0.296 2
ROR1 ROR1 Q01973 Inactive tyrosine-protein kinase transmembrane receptor ROR1 chr1 GO:0048584 Not Cancer Driver No 144 0.154 280 43 0.154 1
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0048584 Not Cancer Driver No 203 0.215 299 71 0.237 5
RPL23_ENST00000394332 RPL23 P62829 60S ribosomal protein L23 chr17 GO:0048584 Not Cancer Driver No 14 0.1 29 4 0.138 0
RPL26 RPL26 P61254 60S ribosomal protein L26 chr17 GO:0048584 Not Cancer Driver No 16 0.11 114 13 0.114 0
RPL37 RPL37 P61927 60S ribosomal protein L37 chr5 GO:0048584 Not Cancer Driver No 12 0.124 83 10 0.12 0
RPS15_ENST00000592588 RPS15 P62841 40S ribosomal protein S15 chr19 GO:0048584 Not Cancer Driver No 13 0.09 59 7 0.119 0
RPS19_ENST00000600467 RPS19 P39019 40S ribosomal protein S19 chr19 GO:0048584 Not Cancer Driver No 15 0.103 61 3 0.049 23
RPS20_ENST00000521262 RPS20 P60866 40S ribosomal protein S20 chr8 GO:0048584 Not Cancer Driver No 18 0.151 53 8 0.151 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0048584 Not Cancer Driver No 22 0.091 48 4 0.083 0
RPS7_ENST00000645674 RPS7 P62081 40S ribosomal protein S7 chr2 GO:0048584 Not Cancer Driver No 29 0.149 39 7 0.179 0
RRAGA RRAGA Q7L523 Ras-related GTP-binding protein A chr9 GO:0048584 Not Cancer Driver No 30 0.096 0 0 0.0 0
RRAGB RRAGB Q5VZM2 Ras-related GTP-binding protein B chrX GO:0048584 Not Cancer Driver No 67 0.179 37 5 0.135 0
RRAGD RRAGD Q9NQL2 Ras-related GTP-binding protein D chr6 GO:0048584 Not Cancer Driver No 42 0.105 83 5 0.06 0
RREB1_ENST00000349384 RREB1 Q92766 Ras-responsive element-binding protein 1 chr6 GO:0048584 Not Cancer Driver No 213 0.126 1152 144 0.125 0
RSAD2 RSAD2 Q8WXG1 Radical S-adenosyl methionine domain-containing protein 2 chr2 GO:0048584 Not Cancer Driver No 68 0.188 22 1 0.045 0
RSPO3 RSPO3 Q9BXY4 R-spondin-3 chr6 GO:0048584 Census Yes 44 0.162 100 12 0.12 0
RTN4 RTN4 Q9NQC3 Reticulon-4 chr2 GO:0048584 Not Cancer Driver No 121 0.102 866 82 0.095 0
RTN4R RTN4R Q9BZR6 Reticulon-4 receptor chr22 GO:0048584 Not Cancer Driver No 38 0.08 148 17 0.115 5
RUNDC3A RUNDC3A Q59EK9 RUN domain-containing protein 3A chr17 GO:0048584 Not Cancer Driver No 39 0.087 175 8 0.046 0
RUVBL1 RUVBL1 Q9Y265 RuvB-like 1 chr3 GO:0048584 Not Cancer Driver No 54 0.118 67 7 0.104 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 GO:0048584 Not Cancer Driver No 62 0.134 100 13 0.13 0
RWDD3 RWDD3 Q9Y3V2 RWD domain-containing protein 3 chr1 GO:0048584 Not Cancer Driver No 40 0.15 12 4 0.333 0
RXRA RXRA P19793 Retinoic acid receptor RXR-alpha chr9 GO:0048584 Compendium Yes 90 0.195 184 26 0.141 0
S100A14_ENST00000368701 S100A14 Q9HCY8 Protein S100-A14 chr1 GO:0048584 Not Cancer Driver No 15 0.144 55 9 0.164 0
S100A7_ENST00000368722 S100A7 P31151 Protein S100-A7 chr1 GO:0048584 Census Yes 39 0.386 28 14 0.5 0
S100A8 S100A8 P05109 Protein S100-A8 chr1 GO:0048584 Not Cancer Driver No 22 0.237 8 4 0.5 0
S100A9 S100A9 P06702 Protein S100-A9 chr1 GO:0048584 Not Cancer Driver No 18 0.158 76 7 0.092 0
S1PR1 S1PR1 P21453 Sphingosine 1-phosphate receptor 1 chr1 GO:0048584 Not Cancer Driver No 86 0.225 29 6 0.207 0
SASH1 SASH1 O94885 SAM and SH3 domain-containing protein 1 chr6 GO:0048584 Not Cancer Driver No 174 0.14 1071 153 0.143 7
SASH3 SASH3 O75995 SAM and SH3 domain-containing protein 3 chrX GO:0048584 Not Cancer Driver No 59 0.155 327 49 0.15 0
SCARF1 SCARF1 Q14162 Scavenger receptor class F member 1 chr17 GO:0048584 Not Cancer Driver No 90 0.108 340 61 0.179 0
SCG2 SCG2 P13521 Secretogranin-2 chr2 GO:0048584 Not Cancer Driver No 116 0.188 531 103 0.194 0
SCIMP SCIMP Q6UWF3 SLP adapter and CSK-interacting membrane protein chr17 GO:0048584 Not Cancer Driver No 10 0.069 73 9 0.123 0
SCT SCT P09683 Secretin chr11 GO:0048584 Not Cancer Driver No 4 0.033 71 3 0.042 0
SCTR SCTR P47872 Secretin receptor chr2 GO:0048584 Not Cancer Driver No 74 0.168 18 1 0.056 0
SCUBE1 SCUBE1 Q8IWY4 Signal peptide, CUB and EGF-like domain-containing protein 1 chr22 GO:0048584 Not Cancer Driver No 149 0.151 97 21 0.216 0
SCUBE3 SCUBE3 Q8IX30 Signal peptide, CUB and EGF-like domain-containing protein 3 chr6 GO:0048584 Not Cancer Driver No 131 0.132 110 17 0.155 2
SDCBP_ENST00000260130 SDCBP O00560 Syntenin-1 chr8 GO:0048584 Not Cancer Driver No 39 0.131 17 2 0.118 0
SEH1L_ENST00000262124 SEH1L Q96EE3 Nucleoporin SEH1 chr18 GO:0048584 Not Cancer Driver No 40 0.111 71 11 0.155 0
SELENON SELENON Q9NZV5 Selenoprotein N chr1 GO:0048584 Not Cancer Driver No 53 0.09 93 5 0.054 11
SELP SELP P16109 P-selectin chr1 GO:0048584 Not Cancer Driver No 226 0.272 14 2 0.143 0
SEMA4D SEMA4D Q92854 Semaphorin-4D chr9 GO:0048584 Not Cancer Driver No 117 0.136 132 15 0.114 0
SEMA5A SEMA5A Q13591 Semaphorin-5A chr5 GO:0048584 Not Cancer Driver No 266 0.248 23 4 0.174 0
SEPT4_ENST00000317268 SEPTIN4 O43236 Septin-4 chr17 GO:0048584 Not Cancer Driver No 61 0.128 220 31 0.141 0
SERINC3_ENST00000255175 SERINC3 Q13530 Serine incorporator 3 chr20 GO:0048584 Not Cancer Driver No 73 0.154 38 9 0.237 0
SERPINA12 SERPINA12 Q8IW75 Serpin A12 chr14 GO:0048584 Not Cancer Driver No 90 0.217 22 3 0.136 0
SERPINE1 SERPINE1 P05121 Plasminogen activator inhibitor 1 chr7 GO:0048584 Not Cancer Driver No 78 0.194 7 2 0.286 0
SERPINF2_ENST00000382061 SERPINF2 P08697 Alpha-2-antiplasmin chr17 GO:0048584 Not Cancer Driver No 62 0.126 112 21 0.188 1
SERPING1 SERPING1 P05155 Plasma protease C1 inhibitor chr11 GO:0048584 Not Cancer Driver No 74 0.148 113 13 0.115 40
SETMAR SETMAR Q53H47 Histone-lysine N-methyltransferase SETMAR chr3 GO:0048584 Not Cancer Driver No 62 0.091 154 12 0.078 0
SFPQ SFPQ P23246 Splicing factor, proline- and glutamine-rich chr1 GO:0048584 Census Yes 59 0.083 595 48 0.081 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0048584 Not Cancer Driver No 40 0.127 39 7 0.179 0
SGTA SGTA O43765 Small glutamine-rich tetratricopeptide repeat-containing protein alpha chr19 GO:0048584 Not Cancer Driver No 38 0.121 159 23 0.145 0
SH2B1 SH2B1 Q9NRF2 SH2B adapter protein 1 chr16 GO:0048584 Not Cancer Driver No 98 0.13 612 84 0.137 0
SH2D1B SH2D1B O14796 SH2 domain-containing protein 1B chr1 GO:0048584 Not Cancer Driver No 34 0.258 0 0 0.0 0
SHANK1 SHANK1 Q9Y566 SH3 and multiple ankyrin repeat domains protein 1 chr19 GO:0048584 Not Cancer Driver No 288 0.133 1659 186 0.112 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0048584 Not Cancer Driver No 56 0.121 139 14 0.101 81
SHKBP1 SHKBP1 Q8TBC3 SH3KBP1-binding protein 1 chr19 GO:0048584 Not Cancer Driver No 93 0.132 281 32 0.114 0
SHLD1 SHLD1 Q8IYI0 Shieldin complex subunit 1 chr20 GO:0048584 Not Cancer Driver No 30 0.146 116 20 0.172 0
SHLD2_ENST00000298784 SHLD2 Q86V20 Shieldin complex subunit 2 chr10 GO:0048584 Not Cancer Driver No 84 0.101 157 14 0.089 0
SHLD3 SHLD3 Q6ZNX1 Shieldin complex subunit 3 chr5 GO:0048584 Not Cancer Driver No 3 0.012 81 1 0.012 0
SHOX2_ENST00000441443 SHOX2 O60902 Short stature homeobox protein 2 chr3 GO:0048584 Not Cancer Driver No 67 0.202 200 40 0.2 0
SIAH1_ENST00000394725 SIAH1 Q8IUQ4 E3 ubiquitin-protein ligase SIAH1 chr16 GO:0048584 Not Cancer Driver No 35 0.124 28 2 0.071 5
SIK3 SIK3 Q9Y2K2 Serine/threonine-protein kinase SIK3 chr11 GO:0048584 Not Cancer Driver No 143 0.108 964 107 0.111 1
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0048584 Not Cancer Driver No 70 0.094 435 31 0.071 0
SKIL_ENST00000259119 SKIL P12757 Ski-like protein chr3 GO:0048584 Not Cancer Driver No 77 0.113 356 32 0.09 0
SKP2 SKP2 Q13309 S-phase kinase-associated protein 2 chr5 GO:0048584 Not Cancer Driver No 52 0.123 52 6 0.115 0
SLAMF1_ENST00000302035 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 GO:0048584 Not Cancer Driver No 82 0.245 64 10 0.156 0
SLC11A1 SLC11A1 P49279 Natural resistance-associated macrophage protein 1 chr2 GO:0048584 Not Cancer Driver No 79 0.144 47 5 0.106 0
SLC15A3 SLC15A3 Q8IY34 Solute carrier family 15 member 3 chr11 GO:0048584 Not Cancer Driver No 63 0.108 43 1 0.023 0
SLC15A4 SLC15A4 Q8N697 Solute carrier family 15 member 4 chr12 GO:0048584 Not Cancer Driver No 66 0.114 23 4 0.174 0
SLC22A13 SLC22A13 Q9Y226 Solute carrier family 22 member 13 chr3 GO:0048584 Not Cancer Driver No 55 0.1 32 3 0.094 0
SLC2A10 SLC2A10 O95528 Solute carrier family 2, facilitated glucose transporter member 10 chr20 GO:0048584 Not Cancer Driver No 98 0.181 72 15 0.208 8
SLC2A4 SLC2A4 P14672 Solute carrier family 2, facilitated glucose transporter member 4 chr17 GO:0048584 Not Cancer Driver No 71 0.139 43 8 0.186 1
SLC35C2_ENST00000372227 SLC35C2 Q9NQQ7 Solute carrier family 35 member C2 chr20 GO:0048584 Not Cancer Driver No 56 0.153 15 2 0.133 0
SLC39A10_ENST00000359634 SLC39A10 Q9ULF5 Zinc transporter ZIP10 chr2 GO:0048584 Not Cancer Driver No 111 0.134 417 63 0.151 0
SLC39A14_ENST00000381237 SLC39A14 Q15043 Metal cation symporter ZIP14 chr8 GO:0048584 Not Cancer Driver No 34 0.069 42 3 0.071 4
SLC46A2 SLC46A2 Q9BY10 Thymic stromal cotransporter homolog chr9 GO:0048584 Not Cancer Driver No 45 0.095 36 3 0.083 0
SLC9A1 SLC9A1 P19634 Sodium/hydrogen exchanger 1 chr1 GO:0048584 Not Cancer Driver No 89 0.109 251 29 0.116 1
SLC9A3R1 SLC9A3R1 O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 chr17 GO:0048584 Not Cancer Driver No 19 0.053 318 16 0.05 4
SLF1 SLF1 Q9BQI6 SMC5-SMC6 complex localization factor protein 1 chr5 GO:0048584 Not Cancer Driver No 104 0.098 167 12 0.072 0
SLF2_ENST00000238961 SLF2 Q8IX21 SMC5-SMC6 complex localization factor protein 2 chr10 GO:0048584 Not Cancer Driver No 112 0.095 725 76 0.105 0
SLIT2 SLIT2 O94813 Slit homolog 2 protein chr4 GO:0048584 Not Cancer Driver No 428 0.28 31 13 0.419 0
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 GO:0048584 Census, Compendium Yes 79 0.169 137 12 0.088 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0048584 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0048584 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMARCA4 SMARCA4 P51532 Transcription activator BRG1 chr19 GO:0048584 Census, Compendium Yes 349 0.212 1072 195 0.182 5
SMARCB1_ENST00000644036 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 GO:0048584 Census, Compendium Yes 64 0.166 141 35 0.248 3
SMCHD1 SMCHD1 A6NHR9 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 chr18 GO:0048584 Not Cancer Driver No 240 0.12 342 45 0.132 45
SMO SMO Q99835 Smoothened homolog chr7 GO:0048584 Census, Compendium Yes 112 0.142 241 27 0.112 1
SMOC2_ENST00000356284 SMOC2 Q9H3U7 SPARC-related modular calcium-binding protein 2 chr6 GO:0048584 Not Cancer Driver No 82 0.184 216 52 0.241 0
SNW1_ENST00000261531 SNW1 Q13573 SNW domain-containing protein 1 chr14 GO:0048584 Not Cancer Driver No 62 0.116 488 56 0.115 0
SNX4 SNX4 O95219 Sorting nexin-4 chr3 GO:0048584 Not Cancer Driver No 31 0.069 101 5 0.05 0
SNX5_ENST00000377759 SNX5 Q9Y5X3 Sorting nexin-5 chr20 GO:0048584 Not Cancer Driver No 33 0.082 91 13 0.143 0
SOCS5 SOCS5 O75159 Suppressor of cytokine signaling 5 chr2 GO:0048584 Not Cancer Driver No 84 0.157 297 46 0.155 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0048584 Not Cancer Driver No 16 0.104 93 9 0.097 79
SORBS1_ENST00000361941 SORBS1 Q9BX66 Sorbin and SH3 domain-containing protein 1 chr10 GO:0048584 Not Cancer Driver No 161 0.125 1111 133 0.12 0
SORL1 SORL1 Q92673 Sortilin-related receptor chr11 GO:0048584 Not Cancer Driver No 374 0.169 87 10 0.115 0
SOS1_ENST00000402219 SOS1 Q07889 Son of sevenless homolog 1 chr2 GO:0048584 Compendium Yes 197 0.148 458 62 0.135 38
SOS2 SOS2 Q07890 Son of sevenless homolog 2 chr14 GO:0048584 Not Cancer Driver No 173 0.13 362 54 0.149 2
SOX11 SOX11 P35716 Transcription factor SOX-11 chr2 GO:0048584 Not Cancer Driver No 61 0.138 368 53 0.144 2
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0048584 Compendium Yes 86 0.169 495 82 0.166 18
SPATC1L SPATC1L Q9H0A9 Speriolin-like protein chr21 GO:0048584 Not Cancer Driver No 30 0.088 179 11 0.061 0
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0048584 Not Cancer Driver No 47 0.122 25 2 0.08 0
SPHK2 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 GO:0048584 Not Cancer Driver No 82 0.125 293 39 0.133 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0048584 Not Cancer Driver No 46 0.17 187 34 0.182 0
SPIDR SPIDR Q14159 DNA repair-scaffolding protein chr8 GO:0048584 Not Cancer Driver No 101 0.11 329 20 0.061 0
SPIRE1 SPIRE1 Q08AE8 Protein spire homolog 1 chr18 GO:0048584 Not Cancer Driver No 78 0.103 414 48 0.116 0
SPIRE2 SPIRE2 Q8WWL2 Protein spire homolog 2 chr16 GO:0048584 Not Cancer Driver No 79 0.111 344 43 0.125 0
SPPL3 SPPL3 Q8TCT6 Signal peptide peptidase-like 3 chr12 GO:0048584 Not Cancer Driver No 45 0.117 23 0 0.0 0
SPRED1 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 GO:0048584 Not Cancer Driver No 71 0.16 194 35 0.18 2
SPRED2 SPRED2 Q7Z698 Sprouty-related, EVH1 domain-containing protein 2 chr2 GO:0048584 Not Cancer Driver No 73 0.175 228 43 0.189 0
SRARP SRARP Q8NEQ6 Steroid receptor-associated and regulated protein chr1 GO:0048584 Not Cancer Driver No 19 0.112 90 9 0.1 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0048584 Census Yes 53 0.099 130 11 0.085 1
SRPX SRPX P78539 Sushi repeat-containing protein SRPX chrX GO:0048584 Not Cancer Driver No 71 0.153 60 10 0.167 0
ST3GAL4_ENST00000534083 ST3GAL4 Q11206 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 chr11 GO:0048584 Not Cancer Driver No 31 0.093 3 2 0.667 0
STAP1_ENST00000396225 STAP1 Q9ULZ2 Signal-transducing adaptor protein 1 chr4 GO:0048584 Not Cancer Driver No 66 0.224 103 18 0.175 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0048584 Census, Compendium Yes 110 0.143 152 15 0.099 19
STAT6_ENST00000543873 STAT6 P42226 Signal transducer and activator of transcription 6 chr12 GO:0048584 Census, Compendium Yes 106 0.125 325 44 0.135 0
STIMATE STIMATE Q86TL2 Store-operated calcium entry regulator STIMATE chr3 GO:0048584 Not Cancer Driver No 27 0.092 61 4 0.066 0
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:0048584 Census, Compendium Yes 75 0.173 135 14 0.104 9
STK24 STK24 Q9Y6E0 Serine/threonine-protein kinase 24 chr13 GO:0048584 Not Cancer Driver No 67 0.151 118 16 0.136 0
STK36_ENST00000440309 STK36 Q9NRP7 Serine/threonine-protein kinase 36 chr2 GO:0048584 Not Cancer Driver No 167 0.127 250 36 0.144 0
STK39 STK39 Q9UEW8 STE20/SPS1-related proline-alanine-rich protein kinase chr2 GO:0048584 Not Cancer Driver No 64 0.117 182 19 0.104 0
STK3_ENST00000419617 STK3 Q13188 Serine/threonine-protein kinase 3 chr8 GO:0048584 Not Cancer Driver No 70 0.143 241 32 0.133 0
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 GO:0048584 Not Cancer Driver No 70 0.144 231 30 0.13 0
STX1A STX1A Q16623 Syntaxin-1A chr7 GO:0048584 Not Cancer Driver No 35 0.122 136 11 0.081 0
STX1B STX1B P61266 Syntaxin-1B chr16 GO:0048584 Not Cancer Driver No 38 0.132 155 20 0.129 2
STX4 STX4 Q12846 Syntaxin-4 chr16 GO:0048584 Not Cancer Driver No 50 0.168 152 20 0.132 0
STX7 STX7 O15400 Syntaxin-7 chr6 GO:0048584 Not Cancer Driver No 29 0.111 164 14 0.085 0
STXBP1_ENST00000373299 STXBP1 P61764 Syntaxin-binding protein 1 chr9 GO:0048584 Not Cancer Driver No 97 0.163 111 23 0.207 18
STYXL1_ENST00000359697 STYXL1 Q9Y6J8 Serine/threonine/tyrosine-interacting-like protein 1 chr7 GO:0048584 Not Cancer Driver No 55 0.176 18 3 0.167 0
SULF1_ENST00000458141 SULF1 Q8IWU6 Extracellular sulfatase Sulf-1 chr8 GO:0048584 Not Cancer Driver No 246 0.282 269 71 0.264 0
SUSD4 SUSD4 Q5VX71 Sushi domain-containing protein 4 chr1 GO:0048584 Not Cancer Driver No 85 0.173 134 27 0.201 0
SWAP70 SWAP70 Q9UH65 Switch-associated protein 70 chr11 GO:0048584 Not Cancer Driver No 44 0.075 271 18 0.066 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0048584 Census Yes 96 0.151 131 27 0.206 5
SYNPO2L SYNPO2L Q9H987 Synaptopodin 2-like protein chr10 GO:0048584 Not Cancer Driver No 103 0.105 950 99 0.104 0
TAF9 TAF9 Q16594 Transcription initiation factor TFIID subunit 9 chr5 GO:0048584 Not Cancer Driver No 25 0.095 203 19 0.094 0
TAOK3 TAOK3 Q9H2K8 Serine/threonine-protein kinase TAO3 chr12 GO:0048584 Not Cancer Driver No 123 0.137 494 64 0.13 0
TBK1 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 GO:0048584 Not Cancer Driver No 101 0.139 42 5 0.119 12
TBX20 TBX20 Q9UMR3 T-box transcription factor TBX20 chr7 GO:0048584 Not Cancer Driver No 117 0.262 201 54 0.269 2
TBX21 TBX21 Q9UL17 T-box transcription factor TBX21 chr17 GO:0048584 Not Cancer Driver No 70 0.131 348 50 0.144 0
TBXA2R_ENST00000375190 TBXA2R P21731 Thromboxane A2 receptor chr19 GO:0048584 Not Cancer Driver No 47 0.137 17 4 0.235 1
TCIM TCIM Q9NR00 Transcriptional and immune response regulator chr8 GO:0048584 Not Cancer Driver No 21 0.198 33 7 0.212 0
TEDC1_ENST00000392523 TEDC1 Q86SX3 Tubulin epsilon and delta complex protein 1 chr14 GO:0048584 Not Cancer Driver No 25 0.051 160 6 0.037 0
TEDC2 TEDC2 Q7L2K0 Tubulin epsilon and delta complex protein 2 chr16 GO:0048584 Not Cancer Driver No 46 0.106 253 26 0.103 0
TEK TEK Q02763 Angiopoietin-1 receptor chr9 GO:0048584 Not Cancer Driver No 219 0.195 126 22 0.175 10
TELO2 TELO2 Q9Y4R8 Telomere length regulation protein TEL2 homolog chr16 GO:0048584 Not Cancer Driver No 113 0.135 154 23 0.149 5
TESPA1 TESPA1 A2RU30 Protein TESPA1 chr12 GO:0048584 Not Cancer Driver No 127 0.244 284 84 0.296 0
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 GO:0048584 Census Yes 89 0.117 80 6 0.075 1
TGFA_ENST00000295400 TGFA P01135 Protransforming growth factor alpha chr2 GO:0048584 Not Cancer Driver No 20 0.125 0 0 0.0 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0048584 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFB1I1 TGFB1I1 O43294 Transforming growth factor beta-1-induced transcript 1 protein chr16 GO:0048584 Not Cancer Driver No 61 0.132 219 34 0.155 0
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0048584 Not Cancer Driver No 63 0.152 47 8 0.17 3
TGFB3 TGFB3 P10600 Transforming growth factor beta-3 proprotein chr14 GO:0048584 Not Cancer Driver No 45 0.109 96 14 0.146 1
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0048584 Not Cancer Driver No 86 0.171 23 3 0.13 15
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0048584 Census, Compendium Yes 106 0.187 60 16 0.267 25
TGFBR3_ENST00000525962 TGFBR3 Q03167 Transforming growth factor beta receptor type 3 chr1 GO:0048584 Not Cancer Driver No 129 0.152 268 41 0.153 0
TGM2 TGM2 P21980 Protein-glutamine gamma-glutamyltransferase 2 chr20 GO:0048584 Not Cancer Driver No 123 0.179 107 26 0.243 0
THBD THBD P07204 Thrombomodulin chr20 GO:0048584 Not Cancer Driver No 39 0.068 51 3 0.059 9
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0048584 Not Cancer Driver No 188 0.161 320 58 0.181 0
THBS4 THBS4 P35443 Thrombospondin-4 chr5 GO:0048584 Not Cancer Driver No 137 0.143 281 40 0.142 0
THRB_ENST00000415021 THRB P10828 Thyroid hormone receptor beta chr3 GO:0048584 Not Cancer Driver No 87 0.189 113 28 0.248 33
TIAL1_ENST00000436547 TIAL1 Q01085 Nucleolysin TIAR chr10 GO:0048584 Not Cancer Driver No 45 0.12 122 12 0.098 0
TICAM2 TICAM2 Q86XR7 TIR domain-containing adapter molecule 2 chr5 GO:0048584 Not Cancer Driver No 35 0.149 88 10 0.114 0
TIMELESS TIMELESS Q9UNS1 Protein timeless homolog chr12 GO:0048584 Not Cancer Driver No 154 0.127 367 51 0.139 0
TIMP3 TIMP3 P35625 Metalloproteinase inhibitor 3 chr22 GO:0048584 Not Cancer Driver No 43 0.204 3 1 0.333 5
TIRAP_ENST00000392680 TIRAP P58753 Toll/interleukin-1 receptor domain-containing adapter protein chr11 GO:0048584 Not Cancer Driver No 28 0.127 80 6 0.075 0
TLR1_ENST00000502213 TLR1 Q15399 Toll-like receptor 1 chr4 GO:0048584 Not Cancer Driver No 107 0.136 1 0 0.0 0
TLR2 TLR2 O60603 Toll-like receptor 2 chr4 GO:0048584 Not Cancer Driver No 108 0.138 0 0 0.0 0
TLR3 TLR3 O15455 Toll-like receptor 3 chr4 GO:0048584 Not Cancer Driver No 123 0.136 0 0 0.0 1
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0048584 Not Cancer Driver No 292 0.348 0 0 0.0 0
TLR5_ENST00000366881 TLR5 O60602 Toll-like receptor 5 chr1 GO:0048584 Not Cancer Driver No 148 0.172 16 3 0.188 0
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:0048584 Not Cancer Driver No 99 0.124 1 0 0.0 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:0048584 Not Cancer Driver No 141 0.137 35 3 0.086 0
TM2D3 TM2D3 Q9BRN9 TM2 domain-containing protein 3 chr15 GO:0048584 Not Cancer Driver No 31 0.126 13 3 0.231 0
TMEM102 TMEM102 Q8N9M5 Transmembrane protein 102 chr17 GO:0048584 Not Cancer Driver No 38 0.075 141 13 0.092 0
TMEM108 TMEM108 Q6UXF1 Transmembrane protein 108 chr3 GO:0048584 Not Cancer Driver No 101 0.176 458 89 0.194 0
TMEM173 STING1 Q86WV6 Stimulator of interferon genes protein chr5 GO:0048584 Not Cancer Driver No 46 0.121 66 13 0.197 3
TMEM259 TMEM259 Q4ZIN3 Membralin chr19 GO:0048584 Not Cancer Driver No 40 0.065 188 9 0.048 0
TMEM33_ENST00000325094 TMEM33 P57088 Transmembrane protein 33 chr4 GO:0048584 Not Cancer Driver No 24 0.097 6 0 0.0 0
TMOD2 TMOD2 Q9NZR1 Tropomodulin-2 chr15 GO:0048584 Not Cancer Driver No 33 0.094 216 22 0.102 0
TMSB4X_ENST00000380633 TMSB4X P62328 Thymosin beta-4 chrX GO:0048584 Census Yes 7 0.159 44 7 0.159 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0048584 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF11A TNFRSF11A Q9Y6Q6 Tumor necrosis factor receptor superfamily member 11A chr18 GO:0048584 Not Cancer Driver No 70 0.114 285 33 0.116 0
TNFSF11 TNFSF11 O14788 Tumor necrosis factor ligand superfamily member 11 chr13 GO:0048584 Not Cancer Driver No 52 0.164 56 1 0.018 1
TNFSF13 TNFSF13 O75888 Tumor necrosis factor ligand superfamily member 13 chr17 GO:0048584 Not Cancer Driver No 14 0.056 109 6 0.055 0
TNFSF13B TNFSF13B Q9Y275 Tumor necrosis factor ligand superfamily member 13B chr13 GO:0048584 Not Cancer Driver No 41 0.144 91 15 0.165 0
TNFSF14 TNFSF14 O43557 Tumor necrosis factor ligand superfamily member 14 chr19 GO:0048584 Not Cancer Driver No 58 0.242 18 1 0.056 0
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 GO:0048584 Not Cancer Driver No 28 0.153 1 0 0.0 0
TP53BP1_ENST00000263801 TP53BP1 Q12888 TP53-binding protein 1 chr15 GO:0048584 Not Cancer Driver No 227 0.115 1632 190 0.116 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0048584 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TP63 TP63 Q9H3D4 Tumor protein 63 chr3 GO:0048584 Census, Compendium Yes 229 0.337 398 143 0.359 28
TPR TPR P12270 Nucleoprotein TPR chr1 GO:0048584 Census Yes 311 0.132 1990 266 0.134 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0048584 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0048584 Not Cancer Driver No 67 0.128 62 7 0.113 0
TRAT1 TRAT1 Q6PIZ9 T-cell receptor-associated transmembrane adapter 1 chr3 GO:0048584 Not Cancer Driver No 86 0.462 129 67 0.519 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0048584 Not Cancer Driver No 43 0.187 27 2 0.074 1
TREML4_ENST00000448827 TREML4 Q6UXN2 Trem-like transcript 4 protein chr6 GO:0048584 Not Cancer Driver No 43 0.215 22 6 0.273 0
TRIM15 TRIM15 Q9C019 Tripartite motif-containing protein 15 chr6 GO:0048584 Not Cancer Driver No 69 0.148 79 11 0.139 0
TRIM16_ENST00000336708 TRIM16 O95361 Tripartite motif-containing protein 16 chr17 GO:0048584 Not Cancer Driver No 64 0.113 132 11 0.083 0
TRIM32 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 GO:0048584 Not Cancer Driver No 82 0.126 87 10 0.115 3
TRIM41 TRIM41 Q8WV44 E3 ubiquitin-protein ligase TRIM41 chr5 GO:0048584 Not Cancer Driver No 69 0.11 385 38 0.099 0
TRIM44 TRIM44 Q96DX7 Tripartite motif-containing protein 44 chr11 GO:0048584 Not Cancer Driver No 40 0.116 272 33 0.121 1
TRIM56 TRIM56 Q9BRZ2 E3 ubiquitin-protein ligase TRIM56 chr7 GO:0048584 Not Cancer Driver No 110 0.146 217 36 0.166 0
TRIM62 TRIM62 Q9BVG3 E3 ubiquitin-protein ligase TRIM62 chr1 GO:0048584 Not Cancer Driver No 58 0.122 80 14 0.175 0
TRIM6_ENST00000278302 TRIM6 Q9C030 Tripartite motif-containing protein 6 chr11 GO:0048584 Not Cancer Driver No 86 0.176 47 15 0.319 0
TRPC3_ENST00000264811 TRPC3 Q13507 Short transient receptor potential channel 3 chr4 GO:0048584 Not Cancer Driver No 200 0.239 23 2 0.087 1
TRPV4 TRPV4 Q9HBA0 Transient receptor potential cation channel subfamily V member 4 chr12 GO:0048584 Not Cancer Driver No 142 0.163 231 34 0.147 44
TRRAP TRRAP Q9Y4A5 Transformation/transcription domain-associated protein chr7 GO:0048584 Census, Compendium Yes 554 0.144 402 59 0.147 8
TSLP TSLP Q969D9 Thymic stromal lymphopoietin chr5 GO:0048584 Not Cancer Driver No 27 0.17 16 0 0.0 0
TSPAN14_ENST00000372156 TSPAN14 Q8NG11 Tetraspanin-14 chr10 GO:0048584 Not Cancer Driver No 38 0.141 0 0 0.0 0
TSPAN5 TSPAN5 P62079 Tetraspanin-5 chr4 GO:0048584 Not Cancer Driver No 49 0.183 0 0 0.0 0
TTBK1 TTBK1 Q5TCY1 Tau-tubulin kinase 1 chr6 GO:0048584 Not Cancer Driver No 193 0.146 1045 154 0.147 0
TTC23 TTC23 Q5W5X9 Tetratricopeptide repeat protein 23 chr15 GO:0048584 Not Cancer Driver No 42 0.094 109 13 0.119 0
TTK TTK P33981 Dual specificity protein kinase TTK chr6 GO:0048584 Not Cancer Driver No 136 0.159 352 46 0.131 0
TUBD1_ENST00000592426 TUBD1 Q9UJT1 Tubulin delta chain chr17 GO:0048584 Not Cancer Driver No 54 0.119 3 0 0.0 0
TWSG1 TWSG1 Q9GZX9 Twisted gastrulation protein homolog 1 chr18 GO:0048584 Not Cancer Driver No 27 0.121 19 3 0.158 0
TXK TXK P42681 Tyrosine-protein kinase TXK chr4 GO:0048584 Not Cancer Driver No 87 0.165 61 9 0.148 0
TXNDC15 TXNDC15 Q96J42 Thioredoxin domain-containing protein 15 chr5 GO:0048584 Not Cancer Driver No 36 0.1 137 15 0.109 0
TYROBP TYROBP O43914 TYRO protein tyrosine kinase-binding protein chr19 GO:0048584 Not Cancer Driver No 24 0.212 28 8 0.286 0
UBB_ENST00000614404 UBB P0CG47 Polyubiquitin-B chr17 GO:0048584 Not Cancer Driver No 20 0.087 102 8 0.078 0
UBE2K UBE2K P61086 Ubiquitin-conjugating enzyme E2 K chr4 GO:0048584 Not Cancer Driver No 24 0.12 33 3 0.091 0
UBE2N UBE2N P61088 Ubiquitin-conjugating enzyme E2 N chr12 GO:0048584 Not Cancer Driver No 25 0.164 24 3 0.125 0
UBE2O UBE2O Q9C0C9 (E3-independent) E2 ubiquitin-conjugating enzyme chr17 GO:0048584 Not Cancer Driver No 129 0.1 716 68 0.095 0
UBE2V2 UBE2V2 Q15819 Ubiquitin-conjugating enzyme E2 variant 2 chr8 GO:0048584 Not Cancer Driver No 22 0.152 76 12 0.158 0
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 GO:0048584 Not Cancer Driver No 141 0.161 136 22 0.162 0
UBQLN1 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 GO:0048584 Not Cancer Driver No 64 0.109 543 58 0.107 0
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX GO:0048584 Not Cancer Driver No 82 0.131 581 79 0.136 8
UCHL5 UCHL5 Q9Y5K5 Ubiquitin carboxyl-terminal hydrolase isozyme L5 chr1 GO:0048584 Not Cancer Driver No 33 0.1 41 7 0.171 0
UCN UCN P55089 Urocortin chr2 GO:0048584 Not Cancer Driver No 7 0.056 61 4 0.066 0
ULK3 ULK3 Q6PHR2 Serine/threonine-protein kinase ULK3 chr15 GO:0048584 Not Cancer Driver No 37 0.078 55 2 0.036 0
UNC5B UNC5B Q8IZJ1 Netrin receptor UNC5B chr10 GO:0048584 Not Cancer Driver No 155 0.164 117 20 0.171 0
USF1 USF1 P22415 Upstream stimulatory factor 1 chr1 GO:0048584 Not Cancer Driver No 52 0.168 271 44 0.162 0
USP13 USP13 Q92995 Ubiquitin carboxyl-terminal hydrolase 13 chr3 GO:0048584 Not Cancer Driver No 121 0.14 224 42 0.188 0
USP15 USP15 Q9Y4E8 Ubiquitin carboxyl-terminal hydrolase 15 chr12 GO:0048584 Not Cancer Driver No 136 0.139 259 39 0.151 0
USP17L2 USP17L2 Q6R6M4 Ubiquitin carboxyl-terminal hydrolase 17 chr8 GO:0048584 Not Cancer Driver No 105 0.198 201 54 0.269 0
USP27X USP27X A6NNY8 Ubiquitin carboxyl-terminal hydrolase 27 chrX GO:0048584 Not Cancer Driver No 31 0.071 69 3 0.043 1
USP29_ENST00000598197 USP29 Q9HBJ7 Ubiquitin carboxyl-terminal hydrolase 29 chr19 GO:0048584 Not Cancer Driver No 291 0.316 432 132 0.306 0
VAMP7_ENST00000286448 VAMP7 P51809 Vesicle-associated membrane protein 7 chrX GO:0048584 Not Cancer Driver No 38 0.173 4 1 0.25 0
VAMP8 VAMP8 Q9BV40 Vesicle-associated membrane protein 8 chr2 GO:0048584 Not Cancer Driver No 9 0.09 27 0 0.0 0
VAV1 VAV1 P15498 Proto-oncogene vav chr19 GO:0048584 Census, Compendium Yes 165 0.195 113 19 0.168 0
VAV2 VAV2 P52735 Guanine nucleotide exchange factor VAV2 chr9 GO:0048584 Not Cancer Driver No 127 0.145 135 17 0.126 0
VAV3 VAV3 Q9UKW4 Guanine nucleotide exchange factor VAV3 chr1 GO:0048584 Not Cancer Driver No 153 0.181 102 18 0.176 0
VDR_ENST00000549336 VDR P11473 Vitamin D3 receptor chr12 GO:0048584 Not Cancer Driver No 64 0.15 102 16 0.157 14
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0048584 Not Cancer Driver No 27 0.116 41 7 0.171 0
VEGFB VEGFB P49765 Vascular endothelial growth factor B chr11 GO:0048584 Not Cancer Driver No 25 0.121 125 22 0.176 0
VEGFC VEGFC P49767 Vascular endothelial growth factor C chr4 GO:0048584 Not Cancer Driver No 128 0.305 37 12 0.324 0
VEGFD VEGFD O43915 Vascular endothelial growth factor D chrX GO:0048584 Not Cancer Driver No 59 0.167 33 6 0.182 0
VPS35 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 GO:0048584 Not Cancer Driver No 68 0.085 99 9 0.091 1
VPS72 VPS72 Q15906 Vacuolar protein sorting-associated protein 72 homolog chr1 GO:0048584 Not Cancer Driver No 43 0.118 329 37 0.112 0
VSIG4 VSIG4 Q9Y279 V-set and immunoglobulin domain-containing protein 4 chrX GO:0048584 Not Cancer Driver No 73 0.183 70 13 0.186 0
VTN VTN P04004 Vitronectin chr17 GO:0048584 Not Cancer Driver No 76 0.159 168 29 0.173 0
WAC WAC Q9BTA9 WW domain-containing adapter protein with coiled-coil chr10 GO:0048584 Not Cancer Driver No 106 0.164 571 95 0.166 0
WAS WAS P42768 Wiskott-Aldrich syndrome protein chrX GO:0048584 Census, Compendium Yes 75 0.149 400 55 0.138 30
WASF1_ENST00000392586 WASF1 Q92558 Wiskott-Aldrich syndrome protein family member 1 chr6 GO:0048584 Not Cancer Driver No 63 0.113 445 49 0.11 0
WBP2_ENST00000254806 WBP2 Q969T9 WW domain-binding protein 2 chr17 GO:0048584 Not Cancer Driver No 26 0.1 102 6 0.059 1
WDFY1 WDFY1 Q8IWB7 WD repeat and FYVE domain-containing protein 1 chr2 GO:0048584 Not Cancer Driver No 51 0.124 24 2 0.083 0
WDR48 WDR48 Q8TAF3 WD repeat-containing protein 48 chr3 GO:0048584 Not Cancer Driver No 61 0.09 125 19 0.152 0
WNK1_ENST00000315939 WNK1 Q9H4A3 Serine/threonine-protein kinase WNK1 chr12 GO:0048584 Not Cancer Driver No 278 0.117 1959 223 0.114 0
WNT1 WNT1 P04628 Proto-oncogene Wnt-1 chr12 GO:0048584 Not Cancer Driver No 29 0.078 25 0 0.0 8
WNT11 WNT11 O96014 Protein Wnt-11 chr11 GO:0048584 Not Cancer Driver No 55 0.155 59 4 0.068 0
WNT16 WNT16 Q9UBV4 Protein Wnt-16 chr7 GO:0048584 Not Cancer Driver No 59 0.162 28 9 0.321 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0048584 Not Cancer Driver No 77 0.219 37 5 0.135 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0048584 Not Cancer Driver No 66 0.174 0 0 0.0 2
WNT5B_ENST00000310594 WNT5B Q9H1J7 Protein Wnt-5b chr12 GO:0048584 Not Cancer Driver No 60 0.167 23 4 0.174 0
WNT7A WNT7A O00755 Protein Wnt-7a chr3 GO:0048584 Not Cancer Driver No 93 0.266 18 9 0.5 4
WRAP53 WRAP53 Q9BUR4 Telomerase Cajal body protein 1 chr17 GO:0048584 Not Cancer Driver No 66 0.12 232 29 0.125 4
WWOX WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 GO:0048584 Not Cancer Driver No 79 0.191 108 9 0.083 3
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0048584 Not Cancer Driver No 19 0.073 169 9 0.053 0
XCL1 XCL1 P47992 Lymphotactin chr1 GO:0048584 Not Cancer Driver No 28 0.246 35 11 0.314 0
XCL2 XCL2 Q9UBD3 Cytokine SCM-1 beta chr1 GO:0048584 Not Cancer Driver No 20 0.175 35 5 0.143 0
XDH XDH P47989 Xanthine dehydrogenase/oxidase chr2 GO:0048584 Not Cancer Driver No 279 0.209 134 24 0.179 1
XRCC1 XRCC1 P18887 DNA repair protein XRCC1 chr19 GO:0048584 Not Cancer Driver No 85 0.134 426 53 0.124 1
XRCC3_ENST00000352127 XRCC3 O43542 DNA repair protein XRCC3 chr14 GO:0048584 Not Cancer Driver No 24 0.069 35 2 0.057 1
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 GO:0048584 Not Cancer Driver No 51 0.101 489 49 0.1 0
YEATS4 YEATS4 O95619 YEATS domain-containing protein 4 chr12 GO:0048584 Not Cancer Driver No 23 0.101 17 1 0.059 0
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 GO:0048584 Not Cancer Driver No 65 0.12 62 10 0.161 0
YPEL3_ENST00000566595 YPEL3 P61236 Protein yippee-like 3 chr16 GO:0048584 Not Cancer Driver No 13 0.109 0 0 0.0 0
ZAP70 ZAP70 P43403 Tyrosine-protein kinase ZAP-70 chr2 GO:0048584 Not Cancer Driver No 126 0.204 117 17 0.145 8
ZBP1 ZBP1 Q9H171 Z-DNA-binding protein 1 chr20 GO:0048584 Not Cancer Driver No 97 0.226 385 80 0.208 0
ZBTB1 ZBTB1 Q9Y2K1 Zinc finger and BTB domain-containing protein 1 chr14 GO:0048584 Not Cancer Driver No 70 0.098 271 27 0.1 0
ZBTB7B_ENST00000368426 ZBTB7B O15156 Zinc finger and BTB domain-containing protein 7B chr1 GO:0048584 Compendium Yes 103 0.191 353 70 0.198 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0048584 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZC3H3 ZC3H3 Q8IXZ2 Zinc finger CCCH domain-containing protein 3 chr8 GO:0048584 Not Cancer Driver No 130 0.137 750 99 0.132 0
ZCCHC3 ZCCHC3 Q9NUD5 Zinc finger CCHC domain-containing protein 3 chr20 GO:0048584 Not Cancer Driver No 28 0.069 160 1 0.006 0
ZCWPW1 ZCWPW1 Q9H0M4 Zinc finger CW-type PWWP domain protein 1 chr7 GO:0048584 Not Cancer Driver No 90 0.139 456 61 0.134 0
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 GO:0048584 Not Cancer Driver No 89 0.124 462 63 0.136 0
ZEB2_ENST00000558170 ZEB2 O60315 Zinc finger E-box-binding homeobox 2 chr2 GO:0048584 Not Cancer Driver No 299 0.246 859 211 0.246 2
ZMIZ1 ZMIZ1 Q9ULJ6 Zinc finger MIZ domain-containing protein 1 chr10 GO:0048584 Not Cancer Driver No 148 0.139 762 111 0.146 5
ZNF385A ZNF385A Q96PM9 Zinc finger protein 385A chr12 GO:0048584 Not Cancer Driver No 43 0.111 312 34 0.109 0
ZNF423 ZNF423 Q2M1K9 Zinc finger protein 423 chr16 GO:0048584 Not Cancer Driver No 340 0.265 416 108 0.26 2
ZP3 ZP3 P21754 Zona pellucida sperm-binding protein 3 chr7 GO:0048584 Not Cancer Driver No 55 0.13 56 11 0.196 1
ZP4 ZP4 Q12836 Zona pellucida sperm-binding protein 4 chr1 GO:0048584 Not Cancer Driver No 189 0.35 46 15 0.326 0
ZSWIM2 ZSWIM2 Q8NEG5 E3 ubiquitin-protein ligase ZSWIM2 chr2 GO:0048584 Not Cancer Driver No 189 0.299 85 30 0.353 0