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Total number of protein in "GO:0048259" GO term:  107

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AAK1 AAK1 Q2M2I8 AP2-associated protein kinase 1 chr2 GO:0048259 Not Cancer Driver No 109 0.113 654 70 0.107 0
ABCA2_ENST00000371605 ABCA2 Q9BZC7 ATP-binding cassette sub-family A member 2 chr9 GO:0048259 Not Cancer Driver No 240 0.099 497 44 0.089 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0048259 Not Cancer Driver No 39 0.16 92 21 0.228 1
AHI1_ENST00000457866 AHI1 Q8N157 Jouberin chr6 GO:0048259 Not Cancer Driver No 120 0.1 500 56 0.112 6
ANGPT1 ANGPT1 Q15389 Angiopoietin-1 chr8 GO:0048259 Not Cancer Driver No 130 0.261 131 24 0.183 1
ANKRD13A ANKRD13A Q8IZ07 Ankyrin repeat domain-containing protein 13A chr12 GO:0048259 Not Cancer Driver No 54 0.092 167 16 0.096 0
ANKRD13B ANKRD13B Q86YJ7 Ankyrin repeat domain-containing protein 13B chr17 GO:0048259 Not Cancer Driver No 64 0.102 290 18 0.062 0
ANKRD13D ANKRD13D Q6ZTN6 Ankyrin repeat domain-containing protein 13D chr11 GO:0048259 Not Cancer Driver No 67 0.111 286 24 0.084 0
ANXA2_ENST00000396024 ANXA2 P07355 Annexin A2 chr15 GO:0048259 Not Cancer Driver No 49 0.145 20 4 0.2 0
AP2M1_ENST00000292807 AP2M1 Q96CW1 AP-2 complex subunit mu chr3 GO:0048259 Not Cancer Driver No 55 0.126 41 9 0.22 1
APELA APELA P0DMC3 Apelin receptor early endogenous ligand chr4 GO:0048259 Not Cancer Driver No 1 0.019 0 0 0.0 0
APLN APLN Q9ULZ1 Apelin chrX GO:0048259 Not Cancer Driver No 8 0.104 51 6 0.118 0
APOA5 APOA5 Q6Q788 Apolipoprotein A-V chr11 GO:0048259 Not Cancer Driver No 51 0.139 178 26 0.146 0
APOC1_ENST00000588802 APOC1 P02654 Apolipoprotein C-I chr19 GO:0048259 Not Cancer Driver No 12 0.145 9 1 0.111 0
APOC2 APOC2 P02655 Apolipoprotein C-II chr19 GO:0048259 Not Cancer Driver No 8 0.079 14 2 0.143 1
APOC3 APOC3 P02656 Apolipoprotein C-III chr11 GO:0048259 Not Cancer Driver No 14 0.141 12 2 0.167 1
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0048259 Not Cancer Driver No 128 0.166 418 71 0.17 17
ARC ARC Q7LC44 Activity-regulated cytoskeleton-associated protein chr8 GO:0048259 Not Cancer Driver No 64 0.162 194 29 0.149 0
ARF1_ENST00000272102 ARF1 P84077 ADP-ribosylation factor 1 chr1 GO:0048259 Not Cancer Driver No 30 0.166 4 2 0.5 2
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 GO:0048259 Not Cancer Driver No 18 0.103 5 0 0.0 0
ARRB1 ARRB1 P49407 Beta-arrestin-1 chr11 GO:0048259 Not Cancer Driver No 49 0.117 154 13 0.084 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0048259 Not Cancer Driver No 46 0.112 122 22 0.18 0
ATAD1_ENST00000328142 ATAD1 Q8NBU5 Outer mitochondrial transmembrane helix translocase chr10 GO:0048259 Not Cancer Driver No 32 0.089 71 3 0.042 0
ATXN2_ENST00000550104 ATXN2 Q99700 Ataxin-2 chr12 GO:0048259 Not Cancer Driver No 146 0.111 1228 134 0.109 0
B2M B2M P61769 Beta-2-microglobulin chr15 GO:0048259 Census, Compendium Yes 34 0.286 5 1 0.2 2
BICD1 BICD1 Q96G01 Protein bicaudal D homolog 1 chr12 GO:0048259 Not Cancer Driver No 124 0.127 656 86 0.131 0
BMP2K BMP2K Q9NSY1 BMP-2-inducible protein kinase chr4 GO:0048259 Not Cancer Driver No 124 0.107 827 89 0.108 0
C3 C3 P01024 Complement C3 chr19 GO:0048259 Not Cancer Driver No 337 0.203 287 50 0.174 12
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0048259 Census, Compendium Yes 115 0.127 512 56 0.109 4
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0048259 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0048259 Not Cancer Driver No 14 0.104 59 6 0.102 0
CD2AP CD2AP Q9Y5K6 CD2-associated protein chr6 GO:0048259 Not Cancer Driver No 80 0.125 456 60 0.132 0
CD63_ENST00000552692 CD63 P08962 CD63 antigen chr12 GO:0048259 Not Cancer Driver No 27 0.113 0 0 0.0 0
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0048259 Not Cancer Driver No 69 0.154 156 27 0.173 0
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0048259 Not Cancer Driver No 144 0.187 680 125 0.184 0
DGKD DGKD Q16760 Diacylglycerol kinase delta chr2 GO:0048259 Not Cancer Driver No 160 0.132 441 60 0.136 0
DKK1 DKK1 O94907 Dickkopf-related protein 1 chr10 GO:0048259 Not Cancer Driver No 58 0.218 47 8 0.17 0
DLG4_ENST00000399506 DLG4 P78352 Disks large homolog 4 chr17 GO:0048259 Not Cancer Driver No 116 0.16 232 55 0.237 0
DNAJC6_ENST00000395325 DNAJC6 O75061 Putative tyrosine-protein phosphatase auxilin chr1 GO:0048259 Not Cancer Driver No 165 0.181 455 82 0.18 1
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 GO:0048259 Census Yes 138 0.159 270 43 0.159 22
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0048259 Not Cancer Driver No 127 0.287 124 45 0.363 0
DRD3_ENST00000460779 DRD3 P35462 D(3) dopamine receptor chr3 GO:0048259 Not Cancer Driver No 88 0.22 45 17 0.378 0
DRD4 DRD4 P21917 D(4) dopamine receptor chr11 GO:0048259 Not Cancer Driver No 26 0.062 109 0 0.0 0
DTNBP1 DTNBP1 Q96EV8 Dysbindin chr6 GO:0048259 Not Cancer Driver No 49 0.14 210 25 0.119 0
EFNB2_ENST00000245323 EFNB2 P52799 Ephrin-B2 chr13 GO:0048259 Not Cancer Driver No 42 0.126 97 15 0.155 0
EGF EGF P01133 Pro-epidermal growth factor chr4 GO:0048259 Not Cancer Driver No 184 0.152 191 25 0.131 1
FLOT1 FLOT1 O75955 Flotillin-1 chr6 GO:0048259 Not Cancer Driver No 43 0.101 122 15 0.123 0
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX GO:0048259 Not Cancer Driver No 124 0.196 327 70 0.214 3
GH1 GH1 P01241 Somatotropin chr17 GO:0048259 Not Cancer Driver No 54 0.249 24 9 0.375 15
GREM1 GREM1 O60565 Gremlin-1 chr15 GO:0048259 Not Cancer Driver No 25 0.136 77 12 0.156 0
GSG1L GSG1L Q6UXU4 Germ cell-specific gene 1-like protein chr16 GO:0048259 Not Cancer Driver No 55 0.166 42 7 0.167 0
HFE HFE Q30201 Hereditary hemochromatosis protein chr6 GO:0048259 Not Cancer Driver No 55 0.158 27 2 0.074 11
HIP1 HIP1 O00291 Huntingtin-interacting protein 1 chr7 GO:0048259 Census, Compendium Yes 137 0.132 510 70 0.137 0
HIP1R HIP1R O75146 Huntingtin-interacting protein 1-related protein chr12 GO:0048259 Not Cancer Driver No 94 0.088 524 34 0.065 0
HIST1H1A H1-1 Q02539 Histone H1.1 chr6 GO:0048259 Not Cancer Driver No 37 0.172 210 35 0.167 0
HNRNPK_ENST00000351839 HNRNPK P61978 Heterogeneous nuclear ribonucleoprotein K chr9 GO:0048259 Not Cancer Driver No 75 0.162 302 59 0.195 0
HPCA HPCA P84074 Neuron-specific calcium-binding protein hippocalcin chr1 GO:0048259 Not Cancer Driver No 24 0.124 42 4 0.095 3
IL4 IL4 P05112 Interleukin-4 chr5 GO:0048259 Not Cancer Driver No 18 0.118 0 0 0.0 0
INSR INSR P06213 Insulin receptor chr19 GO:0048259 Not Cancer Driver No 190 0.137 280 57 0.204 64
ITGAV ITGAV P06756 Integrin alpha-V chr2 GO:0048259 Census Yes 153 0.146 92 9 0.098 0
ITGB3 ITGB3 P05106 Integrin beta-3 chr17 GO:0048259 Not Cancer Driver No 124 0.157 66 5 0.076 30
LDLRAP1 LDLRAP1 Q5SW96 Low density lipoprotein receptor adapter protein 1 chr1 GO:0048259 Not Cancer Driver No 36 0.117 119 17 0.143 1
LRPAP1 LRPAP1 P30533 Alpha-2-macroglobulin receptor-associated protein chr4 GO:0048259 Not Cancer Driver No 41 0.115 188 20 0.106 0
LRRTM1 LRRTM1 Q86UE6 Leucine-rich repeat transmembrane neuronal protein 1 chr2 GO:0048259 Not Cancer Driver No 172 0.33 57 17 0.298 0
LRRTM2 LRRTM2 O43300 Leucine-rich repeat transmembrane neuronal protein 2 chr5 GO:0048259 Not Cancer Driver No 57 0.11 33 1 0.03 0
MAGI2 MAGI2 Q86UL8 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 chr7 GO:0048259 Not Cancer Driver No 305 0.21 1086 201 0.185 0
MKLN1 MKLN1 Q9UL63 Muskelin chr7 GO:0048259 Not Cancer Driver No 85 0.116 91 13 0.143 0
MTMR2 MTMR2 Q13614 Myotubularin-related protein 2 chr11 GO:0048259 Not Cancer Driver No 70 0.109 140 16 0.114 1
NECAB2 NECAB2 Q7Z6G3 N-terminal EF-hand calcium-binding protein 2 chr16 GO:0048259 Not Cancer Driver No 46 0.119 122 9 0.074 0
NTF3_ENST00000331010 NTF3 P20783 Neurotrophin-3 chr12 GO:0048259 Not Cancer Driver No 52 0.202 99 21 0.212 0
NUMB_ENST00000355058 NUMB P49757 Protein numb homolog chr14 GO:0048259 Not Cancer Driver No 70 0.108 490 58 0.118 0
OPHN1 OPHN1 O60890 Oligophrenin-1 chrX GO:0048259 Not Cancer Driver No 122 0.152 302 42 0.139 0
PCSK9 PCSK9 Q8NBP7 Proprotein convertase subtilisin/kexin type 9 chr1 GO:0048259 Not Cancer Driver No 86 0.124 148 27 0.182 9
PICALM PICALM Q13492 Phosphatidylinositol-binding clathrin assembly protein chr11 GO:0048259 Census Yes 89 0.137 320 42 0.131 0
PICK1 PICK1 Q9NRD5 PRKCA-binding protein chr22 GO:0048259 Not Cancer Driver No 50 0.12 49 3 0.061 0
PIK3CB_ENST00000477593 PIK3CB P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 GO:0048259 Census, Compendium Yes 150 0.14 42 4 0.095 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0048259 Not Cancer Driver No 248 0.196 142 30 0.211 1
PPT1 PPT1 P50897 Palmitoyl-protein thioesterase 1 chr1 GO:0048259 Not Cancer Driver No 37 0.121 0 0 0.0 23
PROM2_ENST00000403131 PROM2 Q8N271 Prominin-2 chr2 GO:0048259 Not Cancer Driver No 111 0.133 34 4 0.118 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0048259 Not Cancer Driver No 61 0.131 134 21 0.157 96
RAB21 RAB21 Q9UL25 Ras-related protein Rab-21 chr12 GO:0048259 Not Cancer Driver No 23 0.102 59 4 0.068 0
RABGEF1_ENST00000284957 RABGEF1 Q9UJ41 Rab5 GDP/GTP exchange factor chr7 GO:0048259 Not Cancer Driver No 73 0.149 175 35 0.2 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:0048259 Census, Compendium Yes 66 0.344 2 1 0.5 6
RIN3 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 GO:0048259 Not Cancer Driver No 137 0.139 417 61 0.146 0
RSPO1_ENST00000401068 RSPO1 Q2MKA7 R-spondin-1 chr1 GO:0048259 Not Cancer Driver No 59 0.224 82 16 0.195 0
SCRIB_ENST00000320476 SCRIB Q14160 Protein scribble homolog chr8 GO:0048259 Not Cancer Driver No 196 0.12 1064 135 0.127 2
SCYL2_ENST00000360820 SCYL2 Q6P3W7 SCY1-like protein 2 chr12 GO:0048259 Not Cancer Driver No 103 0.111 328 29 0.088 0
SDCBP_ENST00000260130 SDCBP O00560 Syntenin-1 chr8 GO:0048259 Not Cancer Driver No 39 0.131 17 2 0.118 0
SELE SELE P16581 E-selectin chr1 GO:0048259 Not Cancer Driver No 137 0.225 12 0 0.0 0
SERPINE1 SERPINE1 P05121 Plasminogen activator inhibitor 1 chr7 GO:0048259 Not Cancer Driver No 78 0.194 7 2 0.286 0
SFRP4 SFRP4 Q6FHJ7 Secreted frizzled-related protein 4 chr7 GO:0048259 Census Yes 81 0.234 68 22 0.324 0
SGIP1 SGIP1 Q9BQI5 SH3-containing GRB2-like protein 3-interacting protein 1 chr1 GO:0048259 Not Cancer Driver No 210 0.254 559 152 0.272 0
SH3GL3_ENST00000427482 SH3GL3 Q99963 Endophilin-A3 chr15 GO:0048259 Not Cancer Driver No 88 0.254 83 23 0.277 0
SMAP1 SMAP1 Q8IYB5 Stromal membrane-associated protein 1 chr6 GO:0048259 Not Cancer Driver No 54 0.116 352 46 0.131 0
SNAP91_ENST00000369694 SNAP91 O60641 Clathrin coat assembly protein AP180 chr6 GO:0048259 Not Cancer Driver No 203 0.224 636 118 0.186 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0048259 Census Yes 96 0.151 131 27 0.206 5
SYNJ1 SYNJ1 O43426 Synaptojanin-1 chr21 GO:0048259 Not Cancer Driver No 208 0.132 584 76 0.13 3
TBC1D5_ENST00000253692 TBC1D5 Q92609 TBC1 domain family member 5 chr3 GO:0048259 Not Cancer Driver No 117 0.147 358 58 0.162 0
TF TF P02787 Serotransferrin chr3 GO:0048259 Not Cancer Driver No 135 0.193 21 5 0.238 2
TNK2_ENST00000333602 TNK2 Q07912 Activated CDC42 kinase 1 chr3 GO:0048259 Not Cancer Driver No 137 0.132 593 81 0.137 0
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX GO:0048259 Not Cancer Driver No 82 0.131 581 79 0.136 8
UNC119 UNC119 Q13432 Protein unc-119 homolog A chr17 GO:0048259 Not Cancer Driver No 20 0.083 89 4 0.045 1
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0048259 Not Cancer Driver No 27 0.116 41 7 0.171 0
VTN VTN P04004 Vitronectin chr17 GO:0048259 Not Cancer Driver No 76 0.159 168 29 0.173 0
WASL WASL O00401 Neural Wiskott-Aldrich syndrome protein chr7 GO:0048259 Not Cancer Driver No 72 0.143 394 57 0.145 0
WDR54 WDR54 Q9H977 WD repeat-containing protein 54 chr2 GO:0048259 Not Cancer Driver No 39 0.117 5 0 0.0 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0048259 Not Cancer Driver No 77 0.219 37 5 0.135 0