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Total number of protein in "GO:0046914" GO term:  112

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0046914 Census, Compendium Yes 139 0.123 604 73 0.121 2
ABL2 ABL2 P42684 Tyrosine-protein kinase ABL2 chr1 GO:0046914 Census, Compendium Yes 171 0.145 641 70 0.109 0
ABO_ENST00000611156 ABO P16442 Histo-blood group ABO system transferase chr9 GO:0046914 Not Cancer Driver No 47 0.133 8 1 0.125 0
ACP5_ENST00000433365 ACP5 P13686 Tartrate-resistant acid phosphatase type 5 chr19 GO:0046914 Not Cancer Driver No 51 0.157 31 6 0.194 8
ADCY10 ADCY10 Q96PN6 Adenylate cyclase type 10 chr1 GO:0046914 Not Cancer Driver No 249 0.155 24 4 0.167 0
ADCY2 ADCY2 Q08462 Adenylate cyclase type 2 chr5 GO:0046914 Not Cancer Driver No 303 0.278 95 24 0.253 0
ADPRM ADPRM Q3LIE5 Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase chr17 GO:0046914 Not Cancer Driver No 38 0.111 32 4 0.125 0
APLP1 APLP1 P51693 Amyloid beta precursor like protein 1 chr19 GO:0046914 Not Cancer Driver No 146 0.225 455 98 0.215 0
APLP2 APLP2 Q06481 Amyloid beta precursor like protein 2 chr11 GO:0046914 Not Cancer Driver No 96 0.126 393 48 0.122 0
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0046914 Not Cancer Driver No 128 0.166 418 71 0.17 17
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:0046914 Not Cancer Driver No 41 0.127 83 12 0.145 9
ARG2 ARG2 P78540 Arginase-2, mitochondrial chr14 GO:0046914 Not Cancer Driver No 25 0.071 58 3 0.052 0
ATOX1_ENST00000522710 ATOX1 O00244 Copper transport protein ATOX1 chr5 GO:0046914 Not Cancer Driver No 2 0.029 0 0 0.0 0
ATP13A2 ATP13A2 Q9NQ11 Polyamine-transporting ATPase 13A2 chr1 GO:0046914 Not Cancer Driver No 152 0.129 121 10 0.083 9
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX GO:0046914 Not Cancer Driver No 228 0.152 171 46 0.269 52
B4GALT1 B4GALT1 P15291 Beta-1,4-galactosyltransferase 1 chr9 GO:0046914 Not Cancer Driver No 38 0.095 129 13 0.101 0
B4GALT7 B4GALT7 Q9UBV7 Beta-1,4-galactosyltransferase 7 chr5 GO:0046914 Not Cancer Driver No 32 0.098 44 6 0.136 2
CA3 CA3 P07451 Carbonic anhydrase 3 chr8 GO:0046914 Not Cancer Driver No 61 0.235 64 13 0.203 0
CDIPT_ENST00000569956 CDIPT O14735 CDP-diacylglycerol--inositol 3-phosphatidyltransferase chr16 GO:0046914 Not Cancer Driver No 21 0.099 0 0 0.0 0
COX17_ENST00000497116 COX17 Q14061 Cytochrome c oxidase copper chaperone chr3 GO:0046914 Not Cancer Driver No 7 0.111 15 2 0.133 0
CRNN CRNN Q9UBG3 Cornulin chr1 GO:0046914 Not Cancer Driver No 109 0.22 421 95 0.226 1
DCP2 DCP2 Q8IU60 m7GpppN-mRNA hydrolase chr5 GO:0046914 Not Cancer Driver No 57 0.136 167 24 0.144 0
DYRK2 DYRK2 Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 chr12 GO:0046914 Not Cancer Driver No 77 0.128 294 39 0.133 0
ENDOU ENDOU P21128 Uridylate-specific endoribonuclease chr12 GO:0046914 Not Cancer Driver No 47 0.115 54 8 0.148 0
EXD2 EXD2 Q9NVH0 Exonuclease 3'-5' domain-containing protein 2 chr14 GO:0046914 Not Cancer Driver No 58 0.093 176 15 0.085 0
EXTL2 EXTL2 Q9UBQ6 Exostosin-like 2 chr1 GO:0046914 Not Cancer Driver No 50 0.152 0 0 0.0 0
FAM20C FAM20C Q8IXL6 Extracellular serine/threonine protein kinase FAM20C chr7 GO:0046914 Not Cancer Driver No 33 0.057 188 3 0.016 9
FEN1 FEN1 P39748 Flap endonuclease 1 chr11 GO:0046914 Census Yes 35 0.092 111 11 0.099 0
FLG FLG P20930 Filaggrin chr1 GO:0046914 Not Cancer Driver No 1612 0.397 3956 1593 0.403 0
FLG2 FLG2 Q5D862 Filaggrin-2 chr1 GO:0046914 Not Cancer Driver No 613 0.256 2252 577 0.256 0
FTH1_ENST00000620041 FTH1 P02794 Ferritin heavy chain chr11 GO:0046914 Not Cancer Driver No 20 0.109 57 7 0.123 0
FTHL17 FTHL17 Q9BXU8 Ferritin heavy polypeptide-like 17 chrX GO:0046914 Not Cancer Driver No 63 0.344 9 1 0.111 0
FTL FTL P02792 Ferritin light chain chr19 GO:0046914 Not Cancer Driver No 19 0.109 36 7 0.194 2
FTMT FTMT Q8N4E7 Ferritin, mitochondrial chr5 GO:0046914 Not Cancer Driver No 96 0.397 93 33 0.355 0
FXN FXN Q16595 Frataxin, mitochondrial chr9 GO:0046914 Not Cancer Driver No 16 0.076 73 0 0.0 8
GALNT1 GALNT1 Q10472 Polypeptide N-acetylgalactosaminyltransferase 1 chr18 GO:0046914 Not Cancer Driver No 66 0.118 67 14 0.209 0
GALNT2 GALNT2 Q10471 Polypeptide N-acetylgalactosaminyltransferase 2 chr1 GO:0046914 Not Cancer Driver No 94 0.165 122 22 0.18 2
GALNT3 GALNT3 Q14435 Polypeptide N-acetylgalactosaminyltransferase 3 chr2 GO:0046914 Not Cancer Driver No 85 0.134 103 11 0.107 0
GALNT4 GALNT4 Q8N4A0 Polypeptide N-acetylgalactosaminyltransferase 4 chr12 GO:0046914 Not Cancer Driver No 64 0.111 59 9 0.153 0
GLUL_ENST00000331872 GLUL P15104 Glutamine synthetase chr1 GO:0046914 Not Cancer Driver No 66 0.177 104 21 0.202 2
GYG1 GYG1 P46976 Glycogenin-1 chr3 GO:0046914 Not Cancer Driver No 38 0.109 21 3 0.143 3
HMGCL HMGCL P35914 Hydroxymethylglutaryl-CoA lyase, mitochondrial chr1 GO:0046914 Not Cancer Driver No 17 0.052 8 2 0.25 19
HRNR HRNR Q86YZ3 Hornerin chr1 GO:0046914 Not Cancer Driver No 612 0.215 2767 601 0.217 0
IMPA1_ENST00000256108 IMPA1 P29218 Inositol monophosphatase 1 chr8 GO:0046914 Not Cancer Driver No 36 0.13 3 0 0.0 0
LAP3 LAP3 P28838 Cytosol aminopeptidase chr4 GO:0046914 Not Cancer Driver No 59 0.114 99 14 0.141 0
LARGE1 LARGE1 O95461 Xylosyl- and glucuronyltransferase LARGE1 chr22 GO:0046914 Not Cancer Driver No 131 0.173 92 16 0.174 4
LARGE2_ENST00000325468 LARGE2 Q8N3Y3 Xylosyl- and glucuronyltransferase LARGE2 chr11 GO:0046914 Not Cancer Driver No 89 0.123 98 0 0.0 0
MARC1 MTARC1 Q5VT66 Mitochondrial amidoxime-reducing component 1 chr1 GO:0046914 Not Cancer Driver No 49 0.145 26 6 0.231 0
MARC2 MTARC2 Q969Z3 Mitochondrial amidoxime reducing component 2 chr1 GO:0046914 Not Cancer Driver No 33 0.099 4 0 0.0 0
ME1 ME1 P48163 NADP-dependent malic enzyme chr6 GO:0046914 Not Cancer Driver No 109 0.191 64 10 0.156 0
MGAT1_ENST00000446023 MGAT1 P26572 Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase chr5 GO:0046914 Not Cancer Driver No 67 0.151 44 2 0.045 0
MGAT2 MGAT2 Q10469 Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase chr14 GO:0046914 Not Cancer Driver No 31 0.069 30 3 0.1 3
MGAT5B_ENST00000569840 MGAT5B Q3V5L5 Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B chr17 GO:0046914 Not Cancer Driver No 148 0.187 79 18 0.228 0
MGAT5_ENST00000281923 MGAT5 Q09328 Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A chr2 GO:0046914 Not Cancer Driver No 106 0.143 24 2 0.083 0
MIOX MIOX Q9UGB7 Inositol oxygenase chr22 GO:0046914 Not Cancer Driver No 48 0.168 21 4 0.19 0
MOCOS MOCOS Q96EN8 Molybdenum cofactor sulfurase chr18 GO:0046914 Not Cancer Driver No 117 0.132 189 22 0.116 3
MPPE1 MPPE1 Q53F39 Metallophosphoesterase 1 chr18 GO:0046914 Not Cancer Driver No 39 0.098 27 5 0.185 0
MPPED2 MPPED2 Q15777 Metallophosphoesterase MPPED2 chr11 GO:0046914 Not Cancer Driver No 82 0.279 58 22 0.379 0
MRE11 MRE11 P49959 Double-strand break repair protein MRE11 chr11 GO:0046914 Not Cancer Driver No 84 0.119 292 35 0.12 1
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0046914 Not Cancer Driver No 7 0.103 0 0 0.0 0
MTPAP MTPAP Q9NVV4 Poly(A) RNA polymerase, mitochondrial chr10 GO:0046914 Not Cancer Driver No 73 0.125 136 22 0.162 1
NEK4 NEK4 P51957 Serine/threonine-protein kinase Nek4 chr3 GO:0046914 Not Cancer Driver No 78 0.093 492 49 0.1 0
NOS1_ENST00000317775 NOS1 P29475 Nitric oxide synthase, brain chr12 GO:0046914 Not Cancer Driver No 405 0.282 342 99 0.289 0
NOS3 NOS3 P29474 Nitric oxide synthase, endothelial chr7 GO:0046914 Not Cancer Driver No 168 0.14 347 38 0.11 0
NPEPL1 NPEPL1 Q8NDH3 Probable aminopeptidase NPEPL1 chr20 GO:0046914 Not Cancer Driver No 67 0.128 26 3 0.115 0
NUDT16_ENST00000521288 NUDT16 Q96DE0 U8 snoRNA-decapping enzyme chr3 GO:0046914 Not Cancer Driver No 29 0.149 8 1 0.125 0
NUDT7 NUDT7 P0C024 Peroxisomal coenzyme A diphosphatase NUDT7 chr16 GO:0046914 Not Cancer Driver No 45 0.189 42 4 0.095 0
NUDT8 NUDT8 Q8WV74 Mitochondrial coenzyme A diphosphatase NUDT8 chr11 GO:0046914 Not Cancer Driver No 22 0.093 69 10 0.145 0
PAPOLA PAPOLA P51003 Poly(A) polymerase alpha chr14 GO:0046914 Not Cancer Driver No 97 0.13 293 28 0.096 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0046914 Not Cancer Driver No 11 0.058 30 0 0.0 5
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0046914 Not Cancer Driver No 142 0.228 110 28 0.255 1
PCK2 PCK2 Q16822 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial chr14 GO:0046914 Not Cancer Driver No 91 0.142 139 13 0.094 0
PEPD PEPD P12955 Xaa-Pro dipeptidase chr19 GO:0046914 Not Cancer Driver No 53 0.108 17 2 0.118 4
PIM1 PIM1 P11309 Serine/threonine-protein kinase pim-1 chr6 GO:0046914 Census, Compendium Yes 71 0.227 27 8 0.296 0
PLSCR1 PLSCR1 O15162 Phospholipid scramblase 1 chr3 GO:0046914 Not Cancer Driver No 43 0.135 92 13 0.141 0
PLSCR3 PLSCR3 Q9NRY6 Phospholipid scramblase 3 chr17 GO:0046914 Not Cancer Driver No 30 0.102 62 5 0.081 0
POMGNT1_ENST00000371984 POMGNT1 Q8WZA1 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 chr1 GO:0046914 Not Cancer Driver No 75 0.114 90 13 0.144 20
PPEF1 PPEF1 O14829 Serine/threonine-protein phosphatase with EF-hands 1 chrX GO:0046914 Not Cancer Driver No 127 0.194 66 10 0.152 0
PPEF2 PPEF2 O14830 Serine/threonine-protein phosphatase with EF-hands 2 chr4 GO:0046914 Not Cancer Driver No 144 0.191 130 29 0.223 0
PPM1A_ENST00000395076 PPM1A P35813 Protein phosphatase 1A chr14 GO:0046914 Not Cancer Driver No 60 0.157 134 24 0.179 0
PPM1B PPM1B O75688 Protein phosphatase 1B chr2 GO:0046914 Not Cancer Driver No 65 0.136 243 31 0.128 0
PPM1M_ENST00000323588 PPM1M Q96MI6 Protein phosphatase 1M chr3 GO:0046914 Not Cancer Driver No 23 0.05 87 2 0.023 0
PPM1N PPM1N Q8N819 Probable protein phosphatase 1N chr19 GO:0046914 Not Cancer Driver No 31 0.072 152 7 0.046 0
PRIMPOL_ENST00000503752 PRIMPOL Q96LW4 DNA-directed primase/polymerase protein chr4 GO:0046914 Not Cancer Driver No 50 0.089 92 7 0.076 0
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 GO:0046914 Census Yes 53 0.151 24 0 0.0 2
PRM2_ENST00000241808 PRM2 P04554 Protamine-2 chr16 GO:0046914 Not Cancer Driver No 23 0.225 102 23 0.225 0
PRNP PRNP P04156 Major prion protein chr20 GO:0046914 Not Cancer Driver No 36 0.142 115 7 0.061 18
RIDA RIDA P52758 2-iminobutanoate/2-iminopropanoate deaminase chr8 GO:0046914 Not Cancer Driver No 20 0.146 3 0 0.0 0
RPTN RPTN Q6XPR3 Repetin chr1 GO:0046914 Not Cancer Driver No 218 0.278 718 210 0.292 0
RRM2_ENST00000641198 RRM2 P31350 Ribonucleoside-diphosphate reductase subunit M2 chr2 GO:0046914 Not Cancer Driver No 40 0.103 48 0 0.0 0
S100A2_ENST00000368709 S100A2 P29034 Protein S100-A2 chr1 GO:0046914 Not Cancer Driver No 16 0.163 6 2 0.333 0
S100A4_ENST00000354332 S100A4 P26447 Protein S100-A4 chr1 GO:0046914 Not Cancer Driver No 9 0.089 6 2 0.333 0
S100A7A_ENST00000329256 S100A7A Q86SG5 Protein S100-A7A chr1 GO:0046914 Not Cancer Driver No 31 0.307 20 12 0.6 0
S100G S100G P29377 Protein S100-G chrX GO:0046914 Not Cancer Driver No 8 0.101 35 4 0.114 0
S100P S100P P25815 Protein S100-P chr4 GO:0046914 Not Cancer Driver No 7 0.074 3 1 0.333 0
SLC11A2_ENST00000262051 SLC11A2 P49281 Natural resistance-associated macrophage protein 2 chr12 GO:0046914 Not Cancer Driver No 60 0.106 38 5 0.132 3
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0046914 Not Cancer Driver No 21 0.15 107 13 0.121 5
SNCB_ENST00000510387 SNCB Q16143 Beta-synuclein chr5 GO:0046914 Not Cancer Driver No 23 0.172 110 21 0.191 0
SNCG SNCG O76070 Gamma-synuclein chr10 GO:0046914 Not Cancer Driver No 11 0.087 111 10 0.09 0
SNTN SNTN A6NMZ2 Sentan chr3 GO:0046914 Not Cancer Driver No 24 0.163 62 15 0.242 0
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0046914 Not Cancer Driver No 32 0.144 25 5 0.2 0
SUMF1 SUMF1 Q8NBK3 Formylglycine-generating enzyme chr3 GO:0046914 Not Cancer Driver No 41 0.11 141 15 0.106 16
SUOX_ENST00000356124 SUOX P51687 Sulfite oxidase, mitochondrial chr12 GO:0046914 Not Cancer Driver No 68 0.125 184 32 0.174 11
TCHH TCHH Q07283 Trichohyalin chr1 GO:0046914 Not Cancer Driver No 449 0.231 1292 285 0.221 0
TCHHL1 TCHHL1 Q5QJ38 Trichohyalin-like protein 1 chr1 GO:0046914 Not Cancer Driver No 211 0.233 786 191 0.243 0
TDP2 TDP2 O95551 Tyrosyl-DNA phosphodiesterase 2 chr6 GO:0046914 Not Cancer Driver No 55 0.152 80 10 0.125 0
TF TF P02787 Serotransferrin chr3 GO:0046914 Not Cancer Driver No 135 0.193 21 5 0.238 2
TH TH P07101 Tyrosine 3-monooxygenase chr11 GO:0046914 Not Cancer Driver No 61 0.116 149 21 0.141 38
WRN WRN Q14191 Werner syndrome ATP-dependent helicase chr8 GO:0046914 Census, Compendium Yes 164 0.115 373 41 0.11 2
XPNPEP3 XPNPEP3 Q9NQH7 Xaa-Pro aminopeptidase 3 chr22 GO:0046914 Not Cancer Driver No 64 0.126 128 14 0.109 1
XXYLT1 XXYLT1 Q8NBI6 Xyloside xylosyltransferase 1 chr3 GO:0046914 Not Cancer Driver No 49 0.125 45 6 0.133 0
XYLT2 XYLT2 Q9H1B5 Xylosyltransferase 2 chr17 GO:0046914 Not Cancer Driver No 85 0.098 264 28 0.106 1