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Total number of protein in "GO:0046903" GO term:  250

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCB11 ABCB11 O95342 Bile salt export pump chr2 GO:0046903 Not Cancer Driver No 233 0.176 124 24 0.194 21
ABCB4 ABCB4 P21439 Phosphatidylcholine translocator ABCB4 chr7 GO:0046903 Not Cancer Driver No 243 0.189 74 14 0.189 72
ABCC4_ENST00000376887 ABCC4 O15439 ATP-binding cassette sub-family C member 4 chr13 GO:0046903 Not Cancer Driver No 174 0.131 97 6 0.062 0
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0046903 Not Cancer Driver No 201 0.154 86 8 0.093 0
AGR2 AGR2 O95994 Anterior gradient protein 2 homolog chr7 GO:0046903 Not Cancer Driver No 23 0.131 20 2 0.1 0
AGXT AGXT P21549 Alanine--glyoxylate aminotransferase chr2 GO:0046903 Not Cancer Driver No 56 0.143 20 0 0.0 40
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0046903 Not Cancer Driver No 59 0.171 61 12 0.197 0
ANXA3 ANXA3 P12429 Annexin A3 chr4 GO:0046903 Not Cancer Driver No 53 0.164 22 4 0.182 0
APBA1 APBA1 Q02410 Amyloid-beta A4 precursor protein-binding family A member 1 chr9 GO:0046903 Not Cancer Driver No 149 0.178 556 103 0.185 0
APLN APLN Q9ULZ1 Apelin chrX GO:0046903 Not Cancer Driver No 8 0.104 51 6 0.118 0
APRT APRT P07741 Adenine phosphoribosyltransferase chr16 GO:0046903 Not Cancer Driver No 16 0.089 0 0 0.0 8
AQP1 AQP1 P29972 Aquaporin-1 chr7 GO:0046903 Not Cancer Driver No 39 0.145 4 1 0.25 0
AQP5 AQP5 P55064 Aquaporin-5 chr12 GO:0046903 Not Cancer Driver No 31 0.117 21 2 0.095 5
AQP9 AQP9 O43315 Aquaporin-9 chr15 GO:0046903 Not Cancer Driver No 75 0.254 12 0 0.0 0
ARL8B ARL8B Q9NVJ2 ADP-ribosylation factor-like protein 8B chr3 GO:0046903 Not Cancer Driver No 28 0.151 0 0 0.0 0
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX GO:0046903 Not Cancer Driver No 228 0.152 171 46 0.269 52
ATP7B ATP7B P35670 Copper-transporting ATPase 2 chr13 GO:0046903 Not Cancer Driver No 205 0.14 257 45 0.175 184
BDKRB2 BDKRB2 P30411 B2 bradykinin receptor chr14 GO:0046903 Not Cancer Driver No 81 0.207 0 0 0.0 0
BLK BLK P51451 Tyrosine-protein kinase Blk chr8 GO:0046903 Not Cancer Driver No 94 0.186 75 21 0.28 0
BLOC1S3 BLOC1S3 Q6QNY0 Biogenesis of lysosome-related organelles complex 1 subunit 3 chr19 GO:0046903 Not Cancer Driver No 3 0.015 148 2 0.014 0
BLOC1S6_ENST00000220531 BLOC1S6 Q9UL45 Biogenesis of lysosome-related organelles complex 1 subunit 6 chr15 GO:0046903 Not Cancer Driver No 12 0.07 111 11 0.099 0
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX GO:0046903 Census, Compendium Yes 147 0.223 114 27 0.237 110
CA2 CA2 P00918 Carbonic anhydrase 2 chr8 GO:0046903 Not Cancer Driver No 41 0.158 55 8 0.145 4
CA9 CA9 Q16790 Carbonic anhydrase 9 chr9 GO:0046903 Not Cancer Driver No 72 0.157 274 50 0.182 0
CADPS CADPS Q9ULU8 Calcium-dependent secretion activator 1 chr3 GO:0046903 Not Cancer Driver No 298 0.22 336 71 0.211 0
CADPS2 CADPS2 Q86UW7 Calcium-dependent secretion activator 2 chr7 GO:0046903 Not Cancer Driver No 194 0.15 202 22 0.109 0
CARTPT CARTPT Q16568 Cocaine- and amphetamine-regulated transcript protein chr5 GO:0046903 Not Cancer Driver No 18 0.155 0 0 0.0 0
CASR_ENST00000638421 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0046903 Not Cancer Driver No 304 0.282 189 60 0.317 108
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0046903 Not Cancer Driver No 30 0.169 2 0 0.0 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0046903 Census, Compendium Yes 115 0.127 512 56 0.109 4
CCDC186 CCDC186 Q7Z3E2 Coiled-coil domain-containing protein 186 chr10 GO:0046903 Not Cancer Driver No 99 0.11 702 80 0.114 0
CCKBR CCKBR P32239 Gastrin/cholecystokinin type B receptor chr11 GO:0046903 Not Cancer Driver No 122 0.273 61 22 0.361 0
CCN2 CCN2 P29279 CCN family member 2 chr6 GO:0046903 Not Cancer Driver No 58 0.166 0 0 0.0 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 GO:0046903 Census, Compendium Yes 55 0.186 31 25 0.806 0
CDK16_ENST00000357227 CDK16 Q00536 Cyclin-dependent kinase 16 chrX GO:0046903 Not Cancer Driver No 55 0.111 139 30 0.216 0
CDO1 CDO1 Q16878 Cysteine dioxygenase type 1 chr5 GO:0046903 Not Cancer Driver No 37 0.185 43 4 0.093 0
CEL CEL P19835 Bile salt-activated lipase chr9 GO:0046903 Not Cancer Driver No 101 0.134 280 40 0.143 0
CELSR2 CELSR2 Q9HCU4 Cadherin EGF LAG seven-pass G-type receptor 2 chr1 GO:0046903 Not Cancer Driver No 348 0.119 990 115 0.116 0
CGA_ENST00000627148 CGA P01215 Glycoprotein hormones alpha chain chr6 GO:0046903 Not Cancer Driver No 28 0.241 0 0 0.0 0
CHGA CHGA P10645 Chromogranin-A chr14 GO:0046903 Not Cancer Driver No 46 0.101 421 44 0.105 0
CHRM1 CHRM1 P11229 Muscarinic acetylcholine receptor M1 chr11 GO:0046903 Not Cancer Driver No 63 0.137 131 24 0.183 0
CHRM3_ENST00000615928 CHRM3 P20309 Muscarinic acetylcholine receptor M3 chr1 GO:0046903 Not Cancer Driver No 182 0.308 136 42 0.309 0
CHRM5 CHRM5 P08912 Muscarinic acetylcholine receptor M5 chr15 GO:0046903 Not Cancer Driver No 74 0.139 155 20 0.129 0
CLNK CLNK Q7Z7G1 Cytokine-dependent hematopoietic cell linker chr4 GO:0046903 Not Cancer Driver No 85 0.199 320 73 0.228 0
CLTRN CLTRN Q9HBJ8 Collectrin chrX GO:0046903 Not Cancer Driver No 28 0.126 28 4 0.143 0
COPA_ENST00000241704 COPA P53621 Coatomer subunit alpha chr1 GO:0046903 Not Cancer Driver No 163 0.133 157 18 0.115 4
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 GO:0046903 Not Cancer Driver No 36 0.108 32 7 0.219 0
CORO1A CORO1A P31146 Coronin-1A chr16 GO:0046903 Not Cancer Driver No 51 0.111 126 15 0.119 1
CPLX1 CPLX1 O14810 Complexin-1 chr4 GO:0046903 Not Cancer Driver No 19 0.142 134 19 0.142 0
CPLX2_ENST00000515094 CPLX2 Q6PUV4 Complexin-2 chr5 GO:0046903 Not Cancer Driver No 27 0.201 134 27 0.201 0
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 GO:0046903 Census Yes 25 0.076 277 23 0.083 0
CREB3L1 CREB3L1 Q96BA8 Cyclic AMP-responsive element-binding protein 3-like protein 1 chr11 GO:0046903 Census Yes 68 0.131 372 50 0.134 0
CRHR1 CRHR1 P34998 Corticotropin-releasing factor receptor 1 chr17 GO:0046903 Not Cancer Driver No 75 0.169 0 0 0.0 0
CSF2 CSF2 P04141 Granulocyte-macrophage colony-stimulating factor chr5 GO:0046903 Not Cancer Driver No 11 0.076 34 3 0.088 0
CSN2 CSN2 P05814 Beta-casein chr4 GO:0046903 Not Cancer Driver No 49 0.217 41 12 0.293 0
CSN3 CSN3 P07498 Kappa-casein chr4 GO:0046903 Not Cancer Driver No 49 0.269 87 24 0.276 0
DDR1_ENST00000324771 DDR1 Q08345 Epithelial discoidin domain-containing receptor 1 chr6 GO:0046903 Not Cancer Driver No 123 0.135 253 49 0.194 0
DMTN_ENST00000358242 DMTN Q08495 Dematin chr8 GO:0046903 Not Cancer Driver No 53 0.131 348 46 0.132 0
DOC2A_ENST00000564979 DOC2A Q14183 Double C2-like domain-containing protein alpha chr16 GO:0046903 Not Cancer Driver No 59 0.147 111 16 0.144 0
DOC2B DOC2B Q14184 Double C2-like domain-containing protein beta chr17 GO:0046903 Not Cancer Driver No 10 0.024 197 3 0.015 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0046903 Not Cancer Driver No 127 0.287 124 45 0.363 0
DRD3_ENST00000460779 DRD3 P35462 D(3) dopamine receptor chr3 GO:0046903 Not Cancer Driver No 88 0.22 45 17 0.378 0
DRD4 DRD4 P21917 D(4) dopamine receptor chr11 GO:0046903 Not Cancer Driver No 26 0.062 109 0 0.0 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0046903 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDNRB_ENST00000334286 EDNRB P24530 Endothelin receptor type B chr13 GO:0046903 Not Cancer Driver No 112 0.253 56 19 0.339 6
ENG ENG P17813 Endoglin chr9 GO:0046903 Not Cancer Driver No 60 0.091 114 15 0.132 32
EQTN EQTN Q9NQ60 Equatorin chr9 GO:0046903 Not Cancer Driver No 31 0.105 177 21 0.119 0
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 GO:0046903 Census, Compendium Yes 428 0.327 323 116 0.359 2
FAM129B NIBAN2 Q96TA1 Protein Niban 2 chr9 GO:0046903 Not Cancer Driver No 99 0.133 206 20 0.097 0
FBLN5 FBLN5 Q9UBX5 Fibulin-5 chr14 GO:0046903 Not Cancer Driver No 77 0.172 11 2 0.182 16
FFAR4_ENST00000371481 FFAR4 Q5NUL3 Free fatty acid receptor 4 chr10 GO:0046903 Not Cancer Driver No 47 0.13 0 0 0.0 0
FGF10 FGF10 O15520 Fibroblast growth factor 10 chr5 GO:0046903 Not Cancer Driver No 56 0.269 34 11 0.324 2
FGF7 FGF7 P21781 Fibroblast growth factor 7 chr15 GO:0046903 Not Cancer Driver No 38 0.196 22 4 0.182 0
FOXB1 FOXB1 Q99853 Forkhead box protein B1 chr15 GO:0046903 Not Cancer Driver No 31 0.095 114 5 0.044 0
FOXD1 FOXD1 Q16676 Forkhead box protein D1 chr5 GO:0046903 Not Cancer Driver No 10 0.022 259 5 0.019 0
FZD4 FZD4 Q9ULV1 Frizzled-4 chr11 GO:0046903 Not Cancer Driver No 57 0.106 33 5 0.152 19
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0046903 Census, Compendium Yes 111 0.251 364 87 0.239 2
GHRHR GHRHR Q02643 Growth hormone-releasing hormone receptor chr7 GO:0046903 Not Cancer Driver No 41 0.097 3 0 0.0 5
GHRH_ENST00000237527 GHRH P01286 Somatoliberin chr20 GO:0046903 Not Cancer Driver No 13 0.12 36 4 0.111 0
GHRL_ENST00000457360 GHRL Q9UBU3 Appetite-regulating hormone chr3 GO:0046903 Not Cancer Driver No 20 0.171 52 11 0.212 0
GHSR GHSR Q92847 Growth hormone secretagogue receptor type 1 chr3 GO:0046903 Not Cancer Driver No 85 0.232 4 0 0.0 2
GIPC1 GIPC1 O14908 PDZ domain-containing protein GIPC1 chr19 GO:0046903 Not Cancer Driver No 47 0.141 138 17 0.123 0
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 GO:0046903 Not Cancer Driver No 86 0.225 110 26 0.236 50
GNPTAB GNPTAB Q3T906 N-acetylglucosamine-1-phosphotransferase subunits alpha/beta chr12 GO:0046903 Not Cancer Driver No 144 0.115 259 23 0.089 25
GPAT4 GPAT4 Q86UL3 Glycerol-3-phosphate acyltransferase 4 chr8 GO:0046903 Not Cancer Driver No 64 0.14 3 0 0.0 0
GRM2 GRM2 Q14416 Metabotropic glutamate receptor 2 chr3 GO:0046903 Not Cancer Driver No 143 0.164 24 3 0.125 0
GUCA1B GUCA1B Q9UMX6 Guanylyl cyclase-activating protein 2 chr6 GO:0046903 Not Cancer Driver No 26 0.13 2 0 0.0 1
HCK_ENST00000534862 HCK P08631 Tyrosine-protein kinase HCK chr20 GO:0046903 Not Cancer Driver No 112 0.213 124 25 0.202 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0046903 Census Yes 118 0.143 435 51 0.117 0
HK2 HK2 P52789 Hexokinase-2 chr2 GO:0046903 Not Cancer Driver No 138 0.15 77 7 0.091 0
HRH2_ENST00000231683 HRH2 P25021 Histamine H2 receptor chr5 GO:0046903 Not Cancer Driver No 84 0.234 44 6 0.136 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0046903 Not Cancer Driver No 35 0.165 58 7 0.121 0
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:0046903 Not Cancer Driver No 148 0.347 154 63 0.409 0
KCNN4 KCNN4 O15554 Intermediate conductance calcium-activated potassium channel protein 4 chr19 GO:0046903 Not Cancer Driver No 60 0.141 31 6 0.194 3
KCNQ1 KCNQ1 P51787 Potassium voltage-gated channel subfamily KQT member 1 chr11 GO:0046903 Not Cancer Driver No 78 0.115 219 20 0.091 132
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0046903 Census, Compendium Yes 226 0.232 83 33 0.398 21
KLRF2 KLRF2 D3W0D1 Killer cell lectin-like receptor subfamily F member 2 chr12 GO:0046903 Not Cancer Driver No 1 0.005 0 0 0.0 0
LACRT LACRT Q9GZZ8 Extracellular glycoprotein lacritin chr12 GO:0046903 Not Cancer Driver No 38 0.275 90 27 0.3 0
LAT2 LAT2 Q9GZY6 Linker for activation of T-cells family member 2 chr7 GO:0046903 Not Cancer Driver No 39 0.16 176 29 0.165 0
LAT_ENST00000360872 LAT O43561 Linker for activation of T-cells family member 1 chr16 GO:0046903 Not Cancer Driver No 37 0.141 213 29 0.136 0
LEP LEP P41159 Leptin chr7 GO:0046903 Not Cancer Driver No 29 0.174 0 0 0.0 2
LY6E_ENST00000522024 LY6E Q16553 Lymphocyte antigen 6E chr8 GO:0046903 Not Cancer Driver No 13 0.099 0 0 0.0 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0046903 Census Yes 95 0.186 84 12 0.143 0
M6PR M6PR P20645 Cation-dependent mannose-6-phosphate receptor chr12 GO:0046903 Not Cancer Driver No 16 0.058 35 4 0.114 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0046903 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MILR1 MILR1 Q7Z6M3 Allergin-1 chr17 GO:0046903 Not Cancer Driver No 11 0.032 60 4 0.067 0
MRGPRX2 MRGPRX2 Q96LB1 Mas-related G-protein coupled receptor member X2 chr11 GO:0046903 Not Cancer Driver No 86 0.261 11 2 0.182 0
MTX1 MTX1 Q13505 Metaxin-1 chr1 GO:0046903 Not Cancer Driver No 25 0.054 221 7 0.032 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0046903 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYH9 MYH9 P35579 Myosin-9 chr22 GO:0046903 Census, Compendium Yes 310 0.158 1120 160 0.143 17
NAGPA NAGPA Q9UK23 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase chr16 GO:0046903 Not Cancer Driver No 47 0.091 131 11 0.084 0
NCOR2 NCOR2 Q9Y618 Nuclear receptor corepressor 2 chr12 GO:0046903 Census, Compendium Yes 373 0.148 2355 356 0.151 0
NEURL1 NEURL1 O76050 E3 ubiquitin-protein ligase NEURL1 chr10 GO:0046903 Not Cancer Driver No 62 0.108 153 11 0.072 0
NF1 NF1 P21359 Neurofibromin chr17 GO:0046903 Census, Compendium Yes 375 0.132 406 47 0.116 85
NKG7 NKG7 Q16617 Protein NKG7 chr19 GO:0046903 Not Cancer Driver No 34 0.206 0 0 0.0 0
NLRP5 NLRP5 P59047 NACHT, LRR and PYD domains-containing protein 5 chr19 GO:0046903 Not Cancer Driver No 369 0.307 144 35 0.243 0
NMB_ENST00000360476 NMB P08949 Neuromedin-B chr15 GO:0046903 Not Cancer Driver No 6 0.05 30 2 0.067 0
NME1_ENST00000393196 NME1 P15531 Nucleoside diphosphate kinase A chr17 GO:0046903 Not Cancer Driver No 11 0.072 10 0 0.0 0
NMUR2 NMUR2 Q9GZQ4 Neuromedin-U receptor 2 chr5 GO:0046903 Not Cancer Driver No 139 0.335 5 1 0.2 0
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 GO:0046903 Not Cancer Driver No 207 0.18 201 33 0.164 0
NPPB NPPB P16860 Natriuretic peptides B chr1 GO:0046903 Not Cancer Driver No 31 0.231 104 28 0.269 0
NPR1 NPR1 P16066 Atrial natriuretic peptide receptor 1 chr1 GO:0046903 Not Cancer Driver No 141 0.133 78 16 0.205 0
NPR3 NPR3 P17342 Atrial natriuretic peptide receptor 3 chr5 GO:0046903 Not Cancer Driver No 95 0.176 58 8 0.138 0
NR4A1_ENST00000394825 NR4A1 P22736 Nuclear receptor subfamily 4 group A member 1 chr12 GO:0046903 Not Cancer Driver No 62 0.104 252 24 0.095 0
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:0046903 Census Yes 83 0.133 298 37 0.124 0
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:0046903 Not Cancer Driver No 155 0.189 117 18 0.154 1
OC90 OC90 Q02509 Otoconin-90 chr8 GO:0046903 Not Cancer Driver No 131 0.275 121 41 0.339 0
OXTR OXTR P30559 Oxytocin receptor chr3 GO:0046903 Not Cancer Driver No 46 0.118 18 0 0.0 0
P2RX1 P2RX1 P51575 P2X purinoceptor 1 chr17 GO:0046903 Not Cancer Driver No 59 0.148 14 1 0.071 0
PAM_ENST00000438793 PAM P19021 Peptidyl-glycine alpha-amidating monooxygenase chr5 GO:0046903 Not Cancer Driver No 129 0.133 254 37 0.146 0
PCSK5 PCSK5 Q92824 Proprotein convertase subtilisin/kexin type 5 chr9 GO:0046903 Not Cancer Driver No 319 0.172 168 25 0.149 0
PIK3CD PIK3CD O00329 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform chr1 GO:0046903 Not Cancer Driver No 140 0.134 60 13 0.217 1
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 GO:0046903 Not Cancer Driver No 318 0.289 121 39 0.322 0
PLA2G10 PLA2G10 O15496 Group 10 secretory phospholipase A2 chr16 GO:0046903 Not Cancer Driver No 5 0.03 0 0 0.0 0
PLA2G12A PLA2G12A Q9BZM1 Group XIIA secretory phospholipase A2 chr4 GO:0046903 Not Cancer Driver No 18 0.095 0 0 0.0 0
PLA2G12B PLA2G12B Q9BX93 Group XIIB secretory phospholipase A2-like protein chr10 GO:0046903 Not Cancer Driver No 30 0.154 15 2 0.133 0
PLA2G1B PLA2G1B P04054 Phospholipase A2 chr12 GO:0046903 Not Cancer Driver No 17 0.115 0 0 0.0 0
PLA2G2A_ENST00000375111 PLA2G2A P14555 Phospholipase A2, membrane associated chr1 GO:0046903 Not Cancer Driver No 25 0.174 0 0 0.0 0
PLA2G2C_ENST00000429261 PLA2G2C Q5R387 Putative inactive group IIC secretory phospholipase A2 chr1 GO:0046903 Not Cancer Driver No 18 0.121 10 0 0.0 0
PLA2G2D PLA2G2D Q9UNK4 Group IID secretory phospholipase A2 chr1 GO:0046903 Not Cancer Driver No 27 0.186 0 0 0.0 0
PLA2G2E PLA2G2E Q9NZK7 Group IIE secretory phospholipase A2 chr1 GO:0046903 Not Cancer Driver No 33 0.232 0 0 0.0 0
PLA2G3 PLA2G3 Q9NZ20 Group 3 secretory phospholipase A2 chr22 GO:0046903 Not Cancer Driver No 115 0.226 175 39 0.223 0
PLA2G4A PLA2G4A P47712 Cytosolic phospholipase A2 chr1 GO:0046903 Not Cancer Driver No 149 0.199 129 28 0.217 1
PLA2G4F PLA2G4F Q68DD2 Cytosolic phospholipase A2 zeta chr15 GO:0046903 Not Cancer Driver No 121 0.143 106 6 0.057 0
PLA2G5 PLA2G5 P39877 Phospholipase A2 group V chr1 GO:0046903 Not Cancer Driver No 24 0.174 0 0 0.0 2
PLEK PLEK P08567 Pleckstrin chr2 GO:0046903 Not Cancer Driver No 81 0.231 39 9 0.231 0
PNPLA8 PNPLA8 Q9NP80 Calcium-independent phospholipase A2-gamma chr7 GO:0046903 Not Cancer Driver No 94 0.12 140 18 0.129 0
PORCN PORCN Q9H237 Protein-serine O-palmitoleoyltransferase porcupine chrX GO:0046903 Not Cancer Driver No 77 0.167 0 0 0.0 15
PRKCI PRKCI P41743 Protein kinase C iota type chr3 GO:0046903 Not Cancer Driver No 110 0.185 120 16 0.133 0
PRL PRL P01236 Prolactin chr6 GO:0046903 Not Cancer Driver No 49 0.216 22 1 0.045 0
PRLR PRLR P16471 Prolactin receptor chr5 GO:0046903 Not Cancer Driver No 154 0.248 282 70 0.248 2
PROCA1_ENST00000439862 PROCA1 Q8NCQ7 Protein PROCA1 chr17 GO:0046903 Not Cancer Driver No 50 0.137 240 36 0.15 0
PTGDR PTGDR Q13258 Prostaglandin D2 receptor chr14 GO:0046903 Not Cancer Driver No 74 0.206 14 9 0.643 0
PTGDS PTGDS P41222 Prostaglandin-H2 D-isomerase chr9 GO:0046903 Not Cancer Driver No 31 0.163 13 3 0.231 0
PTGES2 PTGES2 Q9H7Z7 Prostaglandin E synthase 2 chr9 GO:0046903 Not Cancer Driver No 30 0.08 30 1 0.033 0
PTPRN PTPRN Q16849 Receptor-type tyrosine-protein phosphatase-like N chr2 GO:0046903 Not Cancer Driver No 142 0.145 498 73 0.147 0
PTPRN2 PTPRN2 Q92932 Receptor-type tyrosine-protein phosphatase N2 chr7 GO:0046903 Not Cancer Driver No 274 0.27 580 169 0.291 0
RAB11A RAB11A P62491 Ras-related protein Rab-11A chr15 GO:0046903 Not Cancer Driver No 31 0.144 43 4 0.093 0
RAB11B RAB11B Q15907 Ras-related protein Rab-11B chr19 GO:0046903 Not Cancer Driver No 26 0.119 39 3 0.077 2
RAB11FIP2_ENST00000355624 RAB11FIP2 Q7L804 Rab11 family-interacting protein 2 chr10 GO:0046903 Not Cancer Driver No 66 0.129 356 43 0.121 0
RAB11FIP5 RAB11FIP5 Q9BXF6 Rab11 family-interacting protein 5 chr2 GO:0046903 Not Cancer Driver No 83 0.127 533 70 0.131 0
RAB1A RAB1A P62820 Ras-related protein Rab-1A chr2 GO:0046903 Not Cancer Driver No 16 0.078 38 2 0.053 0
RAB27A_ENST00000336787 RAB27A P51159 Ras-related protein Rab-27A chr15 GO:0046903 Not Cancer Driver No 25 0.113 15 4 0.267 3
RAB3A RAB3A P20336 Ras-related protein Rab-3A chr19 GO:0046903 Not Cancer Driver No 25 0.114 43 4 0.093 0
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 GO:0046903 Census, Compendium Yes 89 0.137 169 38 0.225 22
RASGRP1 RASGRP1 O95267 RAS guanyl-releasing protein 1 chr15 GO:0046903 Not Cancer Driver No 96 0.12 191 12 0.063 1
RIMS1 RIMS1 Q86UR5 Regulating synaptic membrane exocytosis protein 1 chr6 GO:0046903 Not Cancer Driver No 403 0.238 1315 306 0.233 1
RIMS3 RIMS3 Q9UJD0 Regulating synaptic membrane exocytosis protein 3 chr1 GO:0046903 Not Cancer Driver No 61 0.198 162 39 0.241 0
RPH3A RPH3A Q9Y2J0 Rabphilin-3A chr12 GO:0046903 Not Cancer Driver No 155 0.223 427 105 0.246 0
S100A13_ENST00000392622 S100A13 Q99584 Protein S100-A13 chr1 GO:0046903 Not Cancer Driver No 12 0.122 6 0 0.0 0
SCNN1B SCNN1B P51168 Amiloride-sensitive sodium channel subunit beta chr16 GO:0046903 Not Cancer Driver No 90 0.141 62 4 0.065 13
SCT SCT P09683 Secretin chr11 GO:0046903 Not Cancer Driver No 4 0.033 71 3 0.042 0
SDF4 SDF4 Q9BRK5 45 kDa calcium-binding protein chr1 GO:0046903 Not Cancer Driver No 48 0.133 187 30 0.16 0
SELENOM_ENST00000611680 SELENOM Q8WWX9 Selenoprotein M chr22 GO:0046903 Not Cancer Driver No 10 0.069 21 2 0.095 0
SELENOT SELENOT P62341 Thioredoxin reductase-like selenoprotein T chr3 GO:0046903 Not Cancer Driver No 25 0.128 0 0 0.0 0
SLC16A10 SLC16A10 Q8TF71 Monocarboxylate transporter 10 chr6 GO:0046903 Not Cancer Driver No 57 0.111 82 2 0.024 0
SLC16A2 SLC16A2 P36021 Monocarboxylate transporter 8 chrX GO:0046903 Not Cancer Driver No 84 0.156 124 12 0.097 20
SLC1A5 SLC1A5 Q15758 Neutral amino acid transporter B(0) chr19 GO:0046903 Not Cancer Driver No 52 0.096 61 7 0.115 0
SLC22A16 SLC22A16 Q86VW1 Solute carrier family 22 member 16 chr6 GO:0046903 Not Cancer Driver No 119 0.206 25 5 0.2 0
SLC22A2 SLC22A2 O15244 Solute carrier family 22 member 2 chr6 GO:0046903 Not Cancer Driver No 126 0.227 31 11 0.355 0
SLC22A4 SLC22A4 Q9H015 Solute carrier family 22 member 4 chr5 GO:0046903 Not Cancer Driver No 57 0.103 8 2 0.25 0
SLC26A6 SLC26A6 Q9BXS9 Solute carrier family 26 member 6 chr3 GO:0046903 Not Cancer Driver No 68 0.09 87 13 0.149 0
SLC26A7_ENST00000617233 SLC26A7 Q8TE54 Anion exchange transporter chr8 GO:0046903 Not Cancer Driver No 150 0.229 1 0 0.0 0
SLC29A1_ENST00000371708 SLC29A1 Q99808 Equilibrative nucleoside transporter 1 chr6 GO:0046903 Not Cancer Driver No 51 0.112 27 4 0.148 0
SLC29A2_ENST00000544554 SLC29A2 Q14542 Equilibrative nucleoside transporter 2 chr11 GO:0046903 Not Cancer Driver No 60 0.132 30 6 0.2 0
SLC44A4 SLC44A4 Q53GD3 Choline transporter-like protein 4 chr6 GO:0046903 Not Cancer Driver No 77 0.108 24 3 0.125 1
SLC4A5_ENST00000377634 SLC4A5 Q9BY07 Electrogenic sodium bicarbonate cotransporter 4 chr2 GO:0046903 Not Cancer Driver No 167 0.147 353 46 0.13 0
SLC51A SLC51A Q86UW1 Organic solute transporter subunit alpha chr3 GO:0046903 Not Cancer Driver No 35 0.103 3 0 0.0 0
SLC51B SLC51B Q86UW2 Organic solute transporter subunit beta chr15 GO:0046903 Not Cancer Driver No 9 0.07 58 5 0.086 0
SLC6A3 SLC6A3 Q01959 Sodium-dependent dopamine transporter chr5 GO:0046903 Not Cancer Driver No 150 0.242 31 8 0.258 2
SLC9A3R1 SLC9A3R1 O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 chr17 GO:0046903 Not Cancer Driver No 19 0.053 318 16 0.05 4
SLC9A4 SLC9A4 Q6AI14 Sodium/hydrogen exchanger 4 chr2 GO:0046903 Not Cancer Driver No 197 0.247 197 77 0.391 0
SNAP23 SNAP23 O00161 Synaptosomal-associated protein 23 chr15 GO:0046903 Not Cancer Driver No 18 0.085 179 16 0.089 0
SNAP25 SNAP25 P60880 Synaptosomal-associated protein 25 chr20 GO:0046903 Not Cancer Driver No 61 0.296 176 49 0.278 1
SNX10_ENST00000396376 SNX10 Q9Y5X0 Sorting nexin-10 chr7 GO:0046903 Not Cancer Driver No 24 0.119 52 8 0.154 4
SOCS2_ENST00000536696 SOCS2 O14508 Suppressor of cytokine signaling 2 chr12 GO:0046903 Not Cancer Driver No 32 0.162 61 2 0.033 0
STAT5A_ENST00000590949 STAT5A P42229 Signal transducer and activator of transcription 5A chr17 GO:0046903 Not Cancer Driver No 89 0.112 125 14 0.112 0
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 GO:0046903 Census, Compendium Yes 93 0.118 144 19 0.132 5
STATH STATH P02808 Statherin chr4 GO:0046903 Not Cancer Driver No 11 0.177 0 0 0.0 0
STX1B STX1B P61266 Syntaxin-1B chr16 GO:0046903 Not Cancer Driver No 38 0.132 155 20 0.129 2
STX3 STX3 Q13277 Syntaxin-3 chr11 GO:0046903 Not Cancer Driver No 51 0.176 129 30 0.233 0
STXBP1_ENST00000373299 STXBP1 P61764 Syntaxin-binding protein 1 chr9 GO:0046903 Not Cancer Driver No 97 0.163 111 23 0.207 18
STXBP2_ENST00000221283 STXBP2 Q15833 Syntaxin-binding protein 2 chr19 GO:0046903 Not Cancer Driver No 77 0.13 80 13 0.163 5
STXBP3 STXBP3 O00186 Syntaxin-binding protein 3 chr1 GO:0046903 Not Cancer Driver No 59 0.1 64 9 0.141 0
SUCNR1 SUCNR1 Q9BXA5 Succinate receptor 1 chr3 GO:0046903 Not Cancer Driver No 51 0.153 0 0 0.0 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0046903 Census Yes 96 0.151 131 27 0.206 5
SYT11 SYT11 Q9BT88 Synaptotagmin-11 chr1 GO:0046903 Not Cancer Driver No 64 0.148 105 23 0.219 0
SYT12_ENST00000527043 SYT12 Q8IV01 Synaptotagmin-12 chr11 GO:0046903 Not Cancer Driver No 71 0.169 73 13 0.178 0
SYT1_ENST00000393240 SYT1 P21579 Synaptotagmin-1 chr12 GO:0046903 Not Cancer Driver No 104 0.246 103 36 0.35 5
SYT2_ENST00000367268 SYT2 Q8N9I0 Synaptotagmin-2 chr1 GO:0046903 Not Cancer Driver No 73 0.174 141 24 0.17 3
SYT5 SYT5 O00445 Synaptotagmin-5 chr19 GO:0046903 Not Cancer Driver No 60 0.155 110 11 0.1 0
SYT6_ENST00000610222 SYT6 Q5T7P8 Synaptotagmin-6 chr1 GO:0046903 Not Cancer Driver No 98 0.192 137 18 0.131 0
SYT7_ENST00000263846 SYT7 O43581 Synaptotagmin-7 chr11 GO:0046903 Not Cancer Driver No 63 0.156 132 25 0.189 0
SYT8 SYT8 Q8NBV8 Synaptotagmin-8 chr11 GO:0046903 Not Cancer Driver No 41 0.102 129 22 0.171 0
TACR2 TACR2 P21452 Substance-K receptor chr10 GO:0046903 Not Cancer Driver No 61 0.153 11 4 0.364 0
TBX3 TBX3 O15119 T-box transcription factor TBX3 chr12 GO:0046903 Census, Compendium Yes 123 0.166 352 57 0.162 2
TMEM167A TMEM167A Q8TBQ9 Protein kish-A chr5 GO:0046903 Not Cancer Driver No 14 0.194 0 0 0.0 0
TMEM167B TMEM167B Q9NRX6 Protein kish-B chr1 GO:0046903 Not Cancer Driver No 7 0.095 0 0 0.0 0
TMEM38B TMEM38B Q9NVV0 Trimeric intracellular cation channel type B chr9 GO:0046903 Not Cancer Driver No 47 0.162 37 7 0.189 0
TMF1 TMF1 P82094 TATA element modulatory factor chr3 GO:0046903 Not Cancer Driver No 109 0.1 946 99 0.105 0
TPD52_ENST00000379097 TPD52 P55327 Tumor protein D52 chr8 GO:0046903 Not Cancer Driver No 25 0.112 177 19 0.107 0
TPH1 TPH1 P17752 Tryptophan 5-hydroxylase 1 chr11 GO:0046903 Not Cancer Driver No 80 0.18 14 3 0.214 0
TRAF3IP2_ENST00000392556 TRAF3IP2 O43734 E3 ubiquitin ligase TRAF3IP2 chr6 GO:0046903 Not Cancer Driver No 59 0.103 410 39 0.095 2
TRAPPC11 TRAPPC11 Q7Z392 Trafficking protein particle complex subunit 11 chr4 GO:0046903 Not Cancer Driver No 109 0.096 44 5 0.114 1
TRPC4_ENST00000379705 TRPC4 Q9UBN4 Short transient receptor potential channel 4 chr13 GO:0046903 Not Cancer Driver No 322 0.33 195 66 0.338 0
TRPV1_ENST00000399756 TRPV1 Q8NER1 Transient receptor potential cation channel subfamily V member 1 chr17 GO:0046903 Not Cancer Driver No 93 0.111 155 18 0.116 0
TRPV4 TRPV4 Q9HBA0 Transient receptor potential cation channel subfamily V member 4 chr12 GO:0046903 Not Cancer Driver No 142 0.163 231 34 0.147 44
TRPV6 TRPV6 Q9H1D0 Transient receptor potential cation channel subfamily V member 6 chr7 GO:0046903 Not Cancer Driver No 183 0.239 77 20 0.26 6
TSG101 TSG101 Q99816 Tumor susceptibility gene 101 protein chr11 GO:0046903 Not Cancer Driver No 46 0.118 159 23 0.145 0
UBE2Q1 UBE2Q1 Q7Z7E8 Ubiquitin-conjugating enzyme E2 Q1 chr1 GO:0046903 Not Cancer Driver No 45 0.107 173 16 0.092 0
UCN UCN P55089 Urocortin chr2 GO:0046903 Not Cancer Driver No 7 0.056 61 4 0.066 0
UGT1A3 UGT1A3 P35503 UDP-glucuronosyltransferase 1A3 chr2 GO:0046903 Not Cancer Driver No 98 0.184 11 2 0.182 0
UMPS UMPS P11172 Uridine 5'-monophosphate synthase chr3 GO:0046903 Not Cancer Driver No 58 0.121 18 2 0.111 3
UNC13A UNC13A Q9UPW8 Protein unc-13 homolog A chr19 GO:0046903 Not Cancer Driver No 300 0.176 454 78 0.172 0
UNC13B_ENST00000378495 UNC13B O14795 Protein unc-13 homolog B chr9 GO:0046903 Not Cancer Driver No 214 0.135 448 77 0.172 0
UNC13C UNC13C Q8NB66 Protein unc-13 homolog C chr15 GO:0046903 Not Cancer Driver No 681 0.308 886 268 0.302 0
UNC13D UNC13D Q70J99 Protein unc-13 homolog D chr17 GO:0046903 Not Cancer Driver No 120 0.11 248 30 0.121 0
UPRT UPRT Q96BW1 Uracil phosphoribosyltransferase homolog chrX GO:0046903 Not Cancer Driver No 64 0.207 76 15 0.197 0
USF2 USF2 Q15853 Upstream stimulatory factor 2 chr19 GO:0046903 Not Cancer Driver No 30 0.087 326 29 0.089 0
VAMP2_ENST00000316509 VAMP2 P63027 Vesicle-associated membrane protein 2 chr17 GO:0046903 Not Cancer Driver No 7 0.06 47 4 0.085 3
VAMP3 VAMP3 Q15836 Vesicle-associated membrane protein 3 chr1 GO:0046903 Not Cancer Driver No 11 0.11 17 1 0.059 0
VAMP7_ENST00000286448 VAMP7 P51809 Vesicle-associated membrane protein 7 chrX GO:0046903 Not Cancer Driver No 38 0.173 4 1 0.25 0
VAMP8 VAMP8 Q9BV40 Vesicle-associated membrane protein 8 chr2 GO:0046903 Not Cancer Driver No 9 0.09 27 0 0.0 0
VDR_ENST00000549336 VDR P11473 Vitamin D3 receptor chr12 GO:0046903 Not Cancer Driver No 64 0.15 102 16 0.157 14
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0046903 Not Cancer Driver No 27 0.116 41 7 0.171 0
VIP VIP P01282 VIP peptides chr6 GO:0046903 Not Cancer Driver No 58 0.341 77 25 0.325 0
WLS_ENST00000262348 WLS Q5T9L3 Protein wntless homolog chr1 GO:0046903 Not Cancer Driver No 71 0.131 14 3 0.214 0
XDH XDH P47989 Xanthine dehydrogenase/oxidase chr2 GO:0046903 Not Cancer Driver No 279 0.209 134 24 0.179 1
ZBTB7B_ENST00000368426 ZBTB7B O15156 Zinc finger and BTB domain-containing protein 7B chr1 GO:0046903 Compendium Yes 103 0.191 353 70 0.198 0
ZP4 ZP4 Q12836 Zona pellucida sperm-binding protein 4 chr1 GO:0046903 Not Cancer Driver No 189 0.35 46 15 0.326 0