Total number of protein in "GO:0046854" GO term: 62
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ATG14 | ATG14 | Q6ZNE5 | Beclin 1-associated autophagy-related key regulator | chr14 | GO:0046854 | Not Cancer Driver | No | 48 | 0.098 | 209 | 24 | 0.115 | 0 |
| ATM_ENST00000452508 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:0046854 | Census, Compendium | Yes | 469 | 0.153 | 225 | 39 | 0.173 | 41 |
| BECN1_ENST00000590099 | BECN1 | Q14457 | Beclin-1 | chr17 | GO:0046854 | Not Cancer Driver | No | 45 | 0.1 | 190 | 19 | 0.1 | 0 |
| BPNT1_ENST00000322067 | BPNT1 | O95861 | 3'(2'),5'-bisphosphate nucleotidase 1 | chr1 | GO:0046854 | Not Cancer Driver | No | 44 | 0.143 | 9 | 0 | 0.0 | 0 |
| CISH_ENST00000348721 | CISH | Q9NSE2 | Cytokine-inducible SH2-containing protein | chr3 | GO:0046854 | Not Cancer Driver | No | 33 | 0.128 | 97 | 8 | 0.082 | 0 |
| EFR3A | EFR3A | Q14156 | Protein EFR3 homolog A | chr8 | GO:0046854 | Not Cancer Driver | No | 114 | 0.139 | 77 | 10 | 0.13 | 0 |
| EFR3B | EFR3B | Q9Y2G0 | Protein EFR3 homolog B | chr2 | GO:0046854 | Not Cancer Driver | No | 42 | 0.051 | 104 | 3 | 0.029 | 0 |
| FAM126A | FAM126A | Q9BYI3 | Hyccin | chr7 | GO:0046854 | Not Cancer Driver | No | 42 | 0.081 | 223 | 18 | 0.081 | 2 |
| FAM126B | FAM126B | Q8IXS8 | Protein FAM126B | chr2 | GO:0046854 | Not Cancer Driver | No | 53 | 0.1 | 238 | 31 | 0.13 | 0 |
| FIG4 | FIG4 | Q92562 | Polyphosphoinositide phosphatase | chr6 | GO:0046854 | Not Cancer Driver | No | 114 | 0.126 | 177 | 26 | 0.147 | 7 |
| IMPA1_ENST00000256108 | IMPA1 | P29218 | Inositol monophosphatase 1 | chr8 | GO:0046854 | Not Cancer Driver | No | 36 | 0.13 | 3 | 0 | 0.0 | 0 |
| IMPA2 | IMPA2 | O14732 | Inositol monophosphatase 2 | chr18 | GO:0046854 | Not Cancer Driver | No | 44 | 0.153 | 21 | 1 | 0.048 | 0 |
| IMPAD1 | BPNT2 | Q9NX62 | Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase | chr8 | GO:0046854 | Not Cancer Driver | No | 45 | 0.125 | 86 | 10 | 0.116 | 2 |
| INPP1 | INPP1 | P49441 | Inositol polyphosphate 1-phosphatase | chr2 | GO:0046854 | Not Cancer Driver | No | 44 | 0.11 | 23 | 1 | 0.043 | 0 |
| INPP4A | INPP4A | Q96PE3 | Inositol polyphosphate-4-phosphatase type I A | chr2 | GO:0046854 | Not Cancer Driver | No | 114 | 0.117 | 153 | 20 | 0.131 | 0 |
| INPP4B_ENST00000513000 | INPP4B | O15327 | Inositol polyphosphate 4-phosphatase type II | chr4 | GO:0046854 | Not Cancer Driver | No | 145 | 0.157 | 191 | 36 | 0.188 | 0 |
| IP6K1 | IP6K1 | Q92551 | Inositol hexakisphosphate kinase 1 | chr3 | GO:0046854 | Not Cancer Driver | No | 50 | 0.113 | 216 | 29 | 0.134 | 0 |
| IP6K2 | IP6K2 | Q9UHH9 | Inositol hexakisphosphate kinase 2 | chr3 | GO:0046854 | Not Cancer Driver | No | 45 | 0.106 | 96 | 10 | 0.104 | 0 |
| IP6K3 | IP6K3 | Q96PC2 | Inositol hexakisphosphate kinase 3 | chr6 | GO:0046854 | Not Cancer Driver | No | 85 | 0.207 | 149 | 34 | 0.228 | 0 |
| IPMK | IPMK | Q8NFU5 | Inositol polyphosphate multikinase | chr10 | GO:0046854 | Not Cancer Driver | No | 50 | 0.12 | 108 | 9 | 0.083 | 0 |
| ITPKA | ITPKA | P23677 | Inositol-trisphosphate 3-kinase A | chr15 | GO:0046854 | Not Cancer Driver | No | 28 | 0.061 | 216 | 7 | 0.032 | 0 |
| ITPKB_ENST00000272117 | ITPKB | P27987 | Inositol-trisphosphate 3-kinase B | chr1 | GO:0046854 | Not Cancer Driver | No | 148 | 0.156 | 719 | 119 | 0.166 | 0 |
| ITPKC | ITPKC | Q96DU7 | Inositol-trisphosphate 3-kinase C | chr19 | GO:0046854 | Not Cancer Driver | No | 78 | 0.114 | 452 | 38 | 0.084 | 0 |
| OCRL | OCRL | Q01968 | Inositol polyphosphate 5-phosphatase OCRL | chrX | GO:0046854 | Not Cancer Driver | No | 151 | 0.168 | 126 | 24 | 0.19 | 41 |
| PI4K2A | PI4K2A | Q9BTU6 | Phosphatidylinositol 4-kinase type 2-alpha | chr10 | GO:0046854 | Not Cancer Driver | No | 43 | 0.09 | 129 | 6 | 0.047 | 0 |
| PI4K2B | PI4K2B | Q8TCG2 | Phosphatidylinositol 4-kinase type 2-beta | chr4 | GO:0046854 | Not Cancer Driver | No | 51 | 0.106 | 99 | 4 | 0.04 | 0 |
| PI4KA | PI4KA | P42356 | Phosphatidylinositol 4-kinase alpha | chr22 | GO:0046854 | Not Cancer Driver | No | 267 | 0.127 | 142 | 11 | 0.077 | 1 |
| PI4KB_ENST00000368873 | PI4KB | Q9UBF8 | Phosphatidylinositol 4-kinase beta | chr1 | GO:0046854 | Not Cancer Driver | No | 93 | 0.114 | 311 | 34 | 0.109 | 0 |
| PIK3C2A | PIK3C2A | O00443 | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha | chr11 | GO:0046854 | Not Cancer Driver | No | 187 | 0.111 | 350 | 43 | 0.123 | 0 |
| PIK3C2B | PIK3C2B | O00750 | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta | chr1 | GO:0046854 | Not Cancer Driver | No | 241 | 0.147 | 425 | 71 | 0.167 | 0 |
| PIK3C2G_ENST00000433979 | PIK3C2G | O75747 | Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma | chr12 | GO:0046854 | Not Cancer Driver | No | 283 | 0.196 | 211 | 37 | 0.175 | 0 |
| PIK3C3 | PIK3C3 | Q8NEB9 | Phosphatidylinositol 3-kinase catalytic subunit type 3 | chr18 | GO:0046854 | Not Cancer Driver | No | 127 | 0.143 | 191 | 34 | 0.178 | 0 |
| PIK3CA | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | GO:0046854 | Census, Compendium | Yes | 1669 | 1.563 | 38 | 11 | 0.289 | 30 |
| PIK3CB_ENST00000477593 | PIK3CB | P42338 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | chr3 | GO:0046854 | Census, Compendium | Yes | 150 | 0.14 | 42 | 4 | 0.095 | 0 |
| PIK3CD | PIK3CD | O00329 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | chr1 | GO:0046854 | Not Cancer Driver | No | 140 | 0.134 | 60 | 13 | 0.217 | 1 |
| PIK3CG | PIK3CG | P48736 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | chr7 | GO:0046854 | Not Cancer Driver | No | 318 | 0.289 | 121 | 39 | 0.322 | 0 |
| PIK3R1 | PIK3R1 | P27986 | Phosphatidylinositol 3-kinase regulatory subunit alpha | chr5 | GO:0046854 | Census, Compendium | Yes | 154 | 0.213 | 268 | 61 | 0.228 | 2 |
| PIK3R2_ENST00000617130 | PIK3R2 | O00459 | Phosphatidylinositol 3-kinase regulatory subunit beta | chr19 | GO:0046854 | Not Cancer Driver | No | 96 | 0.132 | 418 | 47 | 0.112 | 3 |
| PIK3R3_ENST00000372006 | PIK3R3 | Q92569 | Phosphatidylinositol 3-kinase regulatory subunit gamma | chr1 | GO:0046854 | Not Cancer Driver | No | 51 | 0.111 | 149 | 20 | 0.134 | 0 |
| PIK3R4 | PIK3R4 | Q99570 | Phosphoinositide 3-kinase regulatory subunit 4 | chr3 | GO:0046854 | Not Cancer Driver | No | 193 | 0.142 | 315 | 45 | 0.143 | 0 |
| PIK3R6_ENST00000614407 | PIK3R6 | Q5UE93 | Phosphoinositide 3-kinase regulatory subunit 6 | chr17 | GO:0046854 | Not Cancer Driver | No | 100 | 0.133 | 156 | 26 | 0.167 | 0 |
| PIKFYVE | PIKFYVE | Q9Y2I7 | 1-phosphatidylinositol 3-phosphate 5-kinase | chr2 | GO:0046854 | Not Cancer Driver | No | 278 | 0.133 | 848 | 101 | 0.119 | 1 |
| PIP4K2A | PIP4K2A | P48426 | Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha | chr10 | GO:0046854 | Not Cancer Driver | No | 56 | 0.138 | 123 | 15 | 0.122 | 0 |
| PIP4K2C_ENST00000540759 | PIP4K2C | Q8TBX8 | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma | chr12 | GO:0046854 | Not Cancer Driver | No | 62 | 0.147 | 111 | 23 | 0.207 | 0 |
| PIP5K1A | PIP5K1A | Q99755 | Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha | chr1 | GO:0046854 | Not Cancer Driver | No | 74 | 0.132 | 216 | 29 | 0.134 | 0 |
| PIP5K1B | PIP5K1B | O14986 | Phosphatidylinositol 4-phosphate 5-kinase type-1 beta | chr9 | GO:0046854 | Not Cancer Driver | No | 94 | 0.174 | 162 | 36 | 0.222 | 0 |
| PIP5K1C_ENST00000335312 | PIP5K1C | O60331 | Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma | chr19 | GO:0046854 | Not Cancer Driver | No | 98 | 0.147 | 360 | 60 | 0.167 | 1 |
| PIP5KL1 | PIP5KL1 | Q5T9C9 | Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 | chr9 | GO:0046854 | Not Cancer Driver | No | 28 | 0.071 | 74 | 6 | 0.081 | 0 |
| SLA2 | SLA2 | Q9H6Q3 | Src-like-adapter 2 | chr20 | GO:0046854 | Not Cancer Driver | No | 32 | 0.123 | 43 | 9 | 0.209 | 0 |
| SMG1 | SMG1 | Q96Q15 | Serine/threonine-protein kinase SMG1 | chr16 | GO:0046854 | Not Cancer Driver | No | 348 | 0.095 | 605 | 73 | 0.121 | 0 |
| SOCS1 | SOCS1 | O15524 | Suppressor of cytokine signaling 1 | chr16 | GO:0046854 | Census, Compendium | Yes | 22 | 0.104 | 66 | 3 | 0.045 | 2 |
| SOCS2_ENST00000536696 | SOCS2 | O14508 | Suppressor of cytokine signaling 2 | chr12 | GO:0046854 | Not Cancer Driver | No | 32 | 0.162 | 61 | 2 | 0.033 | 0 |
| SOCS3 | SOCS3 | O14543 | Suppressor of cytokine signaling 3 | chr17 | GO:0046854 | Not Cancer Driver | No | 27 | 0.12 | 111 | 14 | 0.126 | 0 |
| SOCS4_ENST00000555846 | SOCS4 | Q8WXH5 | Suppressor of cytokine signaling 4 | chr14 | GO:0046854 | Not Cancer Driver | No | 43 | 0.098 | 136 | 13 | 0.096 | 0 |
| SOCS5 | SOCS5 | O75159 | Suppressor of cytokine signaling 5 | chr2 | GO:0046854 | Not Cancer Driver | No | 84 | 0.157 | 297 | 46 | 0.155 | 0 |
| SOCS6_ENST00000582322 | SOCS6 | O14544 | Suppressor of cytokine signaling 6 | chr18 | GO:0046854 | Not Cancer Driver | No | 81 | 0.151 | 299 | 48 | 0.161 | 0 |
| SYNJ1 | SYNJ1 | O43426 | Synaptojanin-1 | chr21 | GO:0046854 | Not Cancer Driver | No | 208 | 0.132 | 584 | 76 | 0.13 | 3 |
| SYNJ2 | SYNJ2 | O15056 | Synaptojanin-2 | chr6 | GO:0046854 | Not Cancer Driver | No | 189 | 0.126 | 545 | 70 | 0.128 | 0 |
| TMEM150A | TMEM150A | Q86TG1 | Transmembrane protein 150A | chr2 | GO:0046854 | Not Cancer Driver | No | 21 | 0.077 | 4 | 0 | 0.0 | 0 |
| TTC7A_ENST00000319190 | TTC7A | Q9ULT0 | Tetratricopeptide repeat protein 7A | chr2 | GO:0046854 | Not Cancer Driver | No | 109 | 0.127 | 141 | 20 | 0.142 | 9 |
| TTC7B | TTC7B | Q86TV6 | Tetratricopeptide repeat protein 7B | chr14 | GO:0046854 | Not Cancer Driver | No | 135 | 0.16 | 124 | 25 | 0.202 | 0 |
| UVRAG | UVRAG | Q9P2Y5 | UV radiation resistance-associated gene protein | chr11 | GO:0046854 | Not Cancer Driver | No | 89 | 0.127 | 243 | 28 | 0.115 | 0 |