Total number of protein in "GO:0046649" GO term: 214
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0046649 | Census, Compendium | Yes | 139 | 0.123 | 604 | 73 | 0.121 | 2 |
| ADA | ADA | P00813 | Adenosine deaminase | chr20 | GO:0046649 | Not Cancer Driver | No | 50 | 0.138 | 44 | 9 | 0.205 | 27 |
| ADAM17 | ADAM17 | P78536 | Disintegrin and metalloproteinase domain-containing protein 17 | chr2 | GO:0046649 | Not Cancer Driver | No | 80 | 0.097 | 182 | 17 | 0.093 | 0 |
| AICDA | AICDA | Q9GZX7 | Single-stranded DNA cytosine deaminase | chr12 | GO:0046649 | Not Cancer Driver | No | 56 | 0.283 | 0 | 0 | 0.0 | 8 |
| APBB1IP | APBB1IP | Q7Z5R6 | Amyloid beta A4 precursor protein-binding family B member 1-interacting protein | chr10 | GO:0046649 | Not Cancer Driver | No | 130 | 0.195 | 396 | 60 | 0.152 | 0 |
| ARMC5_ENST00000563544 | ARMC5 | Q96C12 | Armadillo repeat-containing protein 5 | chr16 | GO:0046649 | Not Cancer Driver | No | 135 | 0.144 | 267 | 41 | 0.154 | 17 |
| ATAD5 | ATAD5 | Q96QE3 | ATPase family AAA domain-containing protein 5 | chr17 | GO:0046649 | Not Cancer Driver | No | 200 | 0.108 | 1075 | 112 | 0.104 | 0 |
| ATF2 | ATF2 | P15336 | Cyclic AMP-dependent transcription factor ATF-2 | chr2 | GO:0046649 | Not Cancer Driver | No | 65 | 0.129 | 451 | 58 | 0.129 | 0 |
| ATP7A | ATP7A | Q04656 | Copper-transporting ATPase 1 | chrX | GO:0046649 | Not Cancer Driver | No | 228 | 0.152 | 171 | 46 | 0.269 | 52 |
| AXL | AXL | P30530 | Tyrosine-protein kinase receptor UFO | chr19 | GO:0046649 | Not Cancer Driver | No | 168 | 0.188 | 341 | 64 | 0.188 | 0 |
| AZI2 | AZI2 | Q9H6S1 | 5-azacytidine-induced protein 2 | chr3 | GO:0046649 | Not Cancer Driver | No | 31 | 0.079 | 192 | 13 | 0.068 | 0 |
| B2M | B2M | P61769 | Beta-2-microglobulin | chr15 | GO:0046649 | Census, Compendium | Yes | 34 | 0.286 | 5 | 1 | 0.2 | 2 |
| BAG6 | BAG6 | P46379 | Large proline-rich protein BAG6 | chr6 | GO:0046649 | Not Cancer Driver | No | 98 | 0.087 | 861 | 79 | 0.092 | 0 |
| BATF | BATF | Q16520 | Basic leucine zipper transcriptional factor ATF-like | chr14 | GO:0046649 | Not Cancer Driver | No | 28 | 0.224 | 119 | 25 | 0.21 | 0 |
| BAX_ENST00000345358 | BAX | Q07812 | Apoptosis regulator BAX | chr19 | GO:0046649 | Census | Yes | 30 | 0.156 | 39 | 2 | 0.051 | 0 |
| BCL11B | BCL11B | Q9C0K0 | B-cell lymphoma/leukemia 11B | chr14 | GO:0046649 | Census, Compendium | Yes | 156 | 0.174 | 699 | 114 | 0.163 | 2 |
| BCL2_ENST00000333681 | BCL2 | P10415 | Apoptosis regulator Bcl-2 | chr18 | GO:0046649 | Census, Compendium | Yes | 24 | 0.1 | 72 | 5 | 0.069 | 0 |
| BCL3 | BCL3 | P20749 | B-cell lymphoma 3 protein | chr19 | GO:0046649 | Census | Yes | 44 | 0.097 | 259 | 23 | 0.089 | 0 |
| BTN3A1 | BTN3A1 | O00481 | Butyrophilin subfamily 3 member A1 | chr6 | GO:0046649 | Not Cancer Driver | No | 77 | 0.15 | 72 | 18 | 0.25 | 0 |
| C17orf99 | C17orf99 | Q6UX52 | Protein IL-40 | chr17 | GO:0046649 | Not Cancer Driver | No | 16 | 0.06 | 84 | 3 | 0.036 | 0 |
| CADM1_ENST00000452722 | CADM1 | Q9BY67 | Cell adhesion molecule 1 | chr11 | GO:0046649 | Not Cancer Driver | No | 106 | 0.24 | 103 | 28 | 0.272 | 0 |
| CASP8_ENST00000432109 | CASP8 | Q14790 | Caspase-8 | chr2 | GO:0046649 | Census, Compendium | Yes | 142 | 0.296 | 106 | 12 | 0.113 | 1 |
| CCR6_ENST00000349984 | CCR6 | P51684 | C-C chemokine receptor type 6 | chr6 | GO:0046649 | Not Cancer Driver | No | 56 | 0.15 | 13 | 2 | 0.154 | 0 |
| CCR9 | CCR9 | P51686 | C-C chemokine receptor type 9 | chr3 | GO:0046649 | Not Cancer Driver | No | 60 | 0.163 | 0 | 0 | 0.0 | 0 |
| CD180 | CD180 | Q99467 | CD180 antigen | chr5 | GO:0046649 | Not Cancer Driver | No | 105 | 0.159 | 0 | 0 | 0.0 | 0 |
| CD19_ENST00000324662 | CD19 | P15391 | B-lymphocyte antigen CD19 | chr16 | GO:0046649 | Not Cancer Driver | No | 80 | 0.144 | 312 | 46 | 0.147 | 0 |
| CD2 | CD2 | P06729 | T-cell surface antigen CD2 | chr1 | GO:0046649 | Not Cancer Driver | No | 75 | 0.214 | 126 | 35 | 0.278 | 0 |
| CD244 | CD244 | Q9BZW8 | Natural killer cell receptor 2B4 | chr1 | GO:0046649 | Not Cancer Driver | No | 77 | 0.208 | 92 | 22 | 0.239 | 0 |
| CD28 | CD28 | P10747 | T-cell-specific surface glycoprotein CD28 | chr2 | GO:0046649 | Census | Yes | 42 | 0.191 | 18 | 10 | 0.556 | 0 |
| CD40LG | CD40LG | P29965 | CD40 ligand | chrX | GO:0046649 | Not Cancer Driver | No | 56 | 0.215 | 24 | 7 | 0.292 | 32 |
| CD8A_ENST00000283635 | CD8A | P01732 | T-cell surface glycoprotein CD8 alpha chain | chr2 | GO:0046649 | Not Cancer Driver | No | 33 | 0.14 | 28 | 2 | 0.071 | 1 |
| CDH17 | CDH17 | Q12864 | Cadherin-17 | chr8 | GO:0046649 | Census | Yes | 166 | 0.2 | 186 | 35 | 0.188 | 0 |
| CDH26 | CDH26 | Q8IXH8 | Cadherin-like protein 26 | chr20 | GO:0046649 | Not Cancer Driver | No | 157 | 0.189 | 296 | 48 | 0.162 | 0 |
| CDK6 | CDK6 | Q00534 | Cyclin-dependent kinase 6 | chr7 | GO:0046649 | Census | Yes | 40 | 0.123 | 24 | 3 | 0.125 | 1 |
| CLEC4A | CLEC4A | Q9UMR7 | C-type lectin domain family 4 member A | chr12 | GO:0046649 | Not Cancer Driver | No | 35 | 0.148 | 22 | 4 | 0.182 | 0 |
| CLEC4D | CLEC4D | Q8WXI8 | C-type lectin domain family 4 member D | chr12 | GO:0046649 | Not Cancer Driver | No | 59 | 0.274 | 17 | 3 | 0.176 | 0 |
| CLEC4E | CLEC4E | Q9ULY5 | C-type lectin domain family 4 member E | chr12 | GO:0046649 | Not Cancer Driver | No | 56 | 0.256 | 5 | 2 | 0.4 | 0 |
| CMTM7 | CMTM7 | Q96FZ5 | CKLF-like MARVEL transmembrane domain-containing protein 7 | chr3 | GO:0046649 | Not Cancer Driver | No | 25 | 0.143 | 0 | 0 | 0.0 | 0 |
| CORO1A | CORO1A | P31146 | Coronin-1A | chr16 | GO:0046649 | Not Cancer Driver | No | 51 | 0.111 | 126 | 15 | 0.119 | 1 |
| CRACR2A | CRACR2A | Q9BSW2 | EF-hand calcium-binding domain-containing protein 4B | chr12 | GO:0046649 | Not Cancer Driver | No | 88 | 0.12 | 436 | 60 | 0.138 | 0 |
| CRTAM | CRTAM | O95727 | Cytotoxic and regulatory T-cell molecule | chr11 | GO:0046649 | Not Cancer Driver | No | 64 | 0.163 | 135 | 14 | 0.104 | 0 |
| CTNNB1_ENST00000643977 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | GO:0046649 | Census, Compendium | Yes | 415 | 0.531 | 288 | 301 | 1.045 | 14 |
| CXADR | CXADR | P78310 | Coxsackievirus and adenovirus receptor | chr21 | GO:0046649 | Not Cancer Driver | No | 51 | 0.14 | 98 | 19 | 0.194 | 0 |
| DLL1 | DLL1 | O00548 | Delta-like protein 1 | chr6 | GO:0046649 | Not Cancer Driver | No | 115 | 0.159 | 145 | 24 | 0.166 | 1 |
| DNAJA3 | DNAJA3 | Q96EY1 | DnaJ homolog subfamily A member 3, mitochondrial | chr16 | GO:0046649 | Not Cancer Driver | No | 50 | 0.104 | 152 | 21 | 0.138 | 0 |
| DOCK10 | DOCK10 | Q96BY6 | Dedicator of cytokinesis protein 10 | chr2 | GO:0046649 | Not Cancer Driver | No | 368 | 0.168 | 409 | 58 | 0.142 | 0 |
| DOCK11 | DOCK11 | Q5JSL3 | Dedicator of cytokinesis protein 11 | chrX | GO:0046649 | Not Cancer Driver | No | 312 | 0.151 | 240 | 29 | 0.121 | 0 |
| DOCK2 | DOCK2 | Q92608 | Dedicator of cytokinesis protein 2 | chr5 | GO:0046649 | Not Cancer Driver | No | 480 | 0.262 | 266 | 79 | 0.297 | 2 |
| DOCK8 | DOCK8 | Q8NF50 | Dedicator of cytokinesis protein 8 | chr9 | GO:0046649 | Not Cancer Driver | No | 321 | 0.153 | 312 | 60 | 0.192 | 1 |
| ELF4 | ELF4 | Q99607 | ETS-related transcription factor Elf-4 | chrX | GO:0046649 | Census, Compendium | Yes | 88 | 0.133 | 486 | 60 | 0.123 | 0 |
| ENTPD7 | ENTPD7 | Q9NQZ7 | Ectonucleoside triphosphate diphosphohydrolase 7 | chr10 | GO:0046649 | Not Cancer Driver | No | 90 | 0.149 | 26 | 3 | 0.115 | 0 |
| EOMES_ENST00000295743 | EOMES | O95936 | Eomesodermin homolog | chr3 | GO:0046649 | Not Cancer Driver | No | 82 | 0.12 | 436 | 50 | 0.115 | 0 |
| ERCC1_ENST00000589165 | ERCC1 | P07992 | DNA excision repair protein ERCC-1 | chr19 | GO:0046649 | Not Cancer Driver | No | 42 | 0.141 | 105 | 14 | 0.133 | 1 |
| EXO1_ENST00000348581 | EXO1 | Q9UQ84 | Exonuclease 1 | chr1 | GO:0046649 | Not Cancer Driver | No | 123 | 0.145 | 472 | 76 | 0.161 | 0 |
| EXOSC3 | EXOSC3 | Q9NQT5 | Exosome complex component RRP40 | chr9 | GO:0046649 | Not Cancer Driver | No | 18 | 0.065 | 54 | 2 | 0.037 | 4 |
| EXOSC6 | EXOSC6 | Q5RKV6 | Exosome complex component MTR3 | chr16 | GO:0046649 | Not Cancer Driver | No | 3 | 0.011 | 102 | 0 | 0.0 | 0 |
| FADD | FADD | Q13158 | FAS-associated death domain protein | chr11 | GO:0046649 | Not Cancer Driver | No | 26 | 0.125 | 45 | 10 | 0.222 | 1 |
| FCER1G | FCER1G | P30273 | High affinity immunoglobulin epsilon receptor subunit gamma | chr1 | GO:0046649 | Not Cancer Driver | No | 10 | 0.116 | 13 | 2 | 0.154 | 0 |
| FCGR2B | FCGR2B | P31994 | Low affinity immunoglobulin gamma Fc region receptor II-b | chr1 | GO:0046649 | Census | Yes | 51 | 0.165 | 99 | 30 | 0.303 | 0 |
| FCGR3A_ENST00000443193 | FCGR3A | P08637 | Low affinity immunoglobulin gamma Fc region receptor III-A | chr1 | GO:0046649 | Not Cancer Driver | No | 69 | 0.272 | 0 | 0 | 0.0 | 1 |
| FGL2 | FGL2 | Q14314 | Fibroleukin | chr7 | GO:0046649 | Not Cancer Driver | No | 71 | 0.162 | 70 | 12 | 0.171 | 0 |
| FNIP1 | FNIP1 | Q8TF40 | Folliculin-interacting protein 1 | chr5 | GO:0046649 | Not Cancer Driver | No | 143 | 0.123 | 384 | 44 | 0.115 | 0 |
| FOXP1_ENST00000318789 | FOXP1 | Q9H334 | Forkhead box protein P1 | chr3 | GO:0046649 | Census, Compendium | Yes | 109 | 0.161 | 448 | 71 | 0.158 | 3 |
| FUT7 | FUT7 | Q11130 | Alpha-(1,3)-fucosyltransferase 7 | chr9 | GO:0046649 | Not Cancer Driver | No | 28 | 0.082 | 25 | 3 | 0.12 | 0 |
| FYN | FYN | P06241 | Tyrosine-protein kinase Fyn | chr6 | GO:0046649 | Not Cancer Driver | No | 92 | 0.171 | 70 | 13 | 0.186 | 0 |
| FZD5 | FZD5 | Q13467 | Frizzled-5 | chr2 | GO:0046649 | Not Cancer Driver | No | 45 | 0.077 | 58 | 4 | 0.069 | 0 |
| FZD7 | FZD7 | O75084 | Frizzled-7 | chr2 | GO:0046649 | Not Cancer Driver | No | 90 | 0.157 | 22 | 2 | 0.091 | 0 |
| FZD8 | FZD8 | Q9H461 | Frizzled-8 | chr10 | GO:0046649 | Not Cancer Driver | No | 72 | 0.104 | 146 | 3 | 0.021 | 0 |
| GAPT | GAPT | Q8N292 | Protein GAPT | chr5 | GO:0046649 | Not Cancer Driver | No | 41 | 0.261 | 83 | 27 | 0.325 | 0 |
| GATA3_ENST00000346208 | GATA3 | P23771 | Trans-acting T-cell-specific transcription factor GATA-3 | chr10 | GO:0046649 | Census, Compendium | Yes | 111 | 0.251 | 364 | 87 | 0.239 | 2 |
| GBA_ENST00000368373 | GBA | P04062 | Lysosomal acid glucosylceramidase | chr1 | GO:0046649 | Not Cancer Driver | No | 74 | 0.138 | 38 | 5 | 0.132 | 171 |
| GLI3 | GLI3 | P10071 | Transcriptional activator GLI3 | chr7 | GO:0046649 | Not Cancer Driver | No | 385 | 0.244 | 1352 | 327 | 0.242 | 7 |
| GPR183 | GPR183 | P32249 | G-protein coupled receptor 183 | chr13 | GO:0046649 | Not Cancer Driver | No | 53 | 0.147 | 25 | 3 | 0.12 | 0 |
| GPR18_ENST00000397470 | GPR18 | Q14330 | N-arachidonyl glycine receptor | chr13 | GO:0046649 | Not Cancer Driver | No | 36 | 0.109 | 0 | 0 | 0.0 | 0 |
| HECTD1 | HECTD1 | Q9ULT8 | E3 ubiquitin-protein ligase HECTD1 | chr14 | GO:0046649 | Not Cancer Driver | No | 274 | 0.105 | 991 | 108 | 0.109 | 0 |
| HLA-A_ENST00000376809 | HLA-A | P04439 | HLA class I histocompatibility antigen, A alpha chain | chr6 | GO:0046649 | Census, Compendium | Yes | 128 | 0.351 | 125 | 60 | 0.48 | 0 |
| HLA-E | HLA-E | P13747 | HLA class I histocompatibility antigen, alpha chain E | chr6 | GO:0046649 | Not Cancer Driver | No | 63 | 0.176 | 138 | 39 | 0.283 | 0 |
| HMGB1_ENST00000405805 | HMGB1 | P09429 | High mobility group protein B1 | chr13 | GO:0046649 | Not Cancer Driver | No | 25 | 0.116 | 203 | 20 | 0.099 | 0 |
| HSPD1 | HSPD1 | P10809 | 60 kDa heat shock protein, mitochondrial | chr2 | GO:0046649 | Not Cancer Driver | No | 61 | 0.106 | 82 | 6 | 0.073 | 2 |
| ICAM1 | ICAM1 | P05362 | Intercellular adhesion molecule 1 | chr19 | GO:0046649 | Not Cancer Driver | No | 61 | 0.115 | 251 | 28 | 0.112 | 0 |
| IFNA10 | IFNA10 | P01566 | Interferon alpha-10 | chr9 | GO:0046649 | Not Cancer Driver | No | 40 | 0.212 | 1 | 0 | 0.0 | 0 |
| IFNA13_ENST00000449498 | IFNA13 | P01562 | Interferon alpha-1/13 | chr9 | GO:0046649 | Not Cancer Driver | No | 39 | 0.206 | 2 | 0 | 0.0 | 0 |
| IFNA14 | IFNA14 | P01570 | Interferon alpha-14 | chr9 | GO:0046649 | Not Cancer Driver | No | 39 | 0.206 | 1 | 1 | 1.0 | 0 |
| IFNA16 | IFNA16 | P05015 | Interferon alpha-16 | chr9 | GO:0046649 | Not Cancer Driver | No | 61 | 0.323 | 1 | 0 | 0.0 | 0 |
| IFNA17 | IFNA17 | P01571 | Interferon alpha-17 | chr9 | GO:0046649 | Not Cancer Driver | No | 37 | 0.196 | 0 | 0 | 0.0 | 0 |
| IFNA2 | IFNA2 | P01563 | Interferon alpha-2 | chr9 | GO:0046649 | Not Cancer Driver | No | 38 | 0.202 | 2 | 0 | 0.0 | 0 |
| IFNA21 | IFNA21 | P01568 | Interferon alpha-21 | chr9 | GO:0046649 | Not Cancer Driver | No | 34 | 0.18 | 0 | 0 | 0.0 | 0 |
| IFNA4 | IFNA4 | P05014 | Interferon alpha-4 | chr9 | GO:0046649 | Not Cancer Driver | No | 39 | 0.206 | 1 | 0 | 0.0 | 0 |
| IFNA5 | IFNA5 | P01569 | Interferon alpha-5 | chr9 | GO:0046649 | Not Cancer Driver | No | 36 | 0.19 | 1 | 0 | 0.0 | 0 |
| IFNA6 | IFNA6 | P05013 | Interferon alpha-6 | chr9 | GO:0046649 | Not Cancer Driver | No | 28 | 0.148 | 4 | 0 | 0.0 | 0 |
| IFNA7 | IFNA7 | P01567 | Interferon alpha-7 | chr9 | GO:0046649 | Not Cancer Driver | No | 43 | 0.228 | 1 | 1 | 1.0 | 0 |
| IFNA8 | IFNA8 | P32881 | Interferon alpha-8 | chr9 | GO:0046649 | Not Cancer Driver | No | 43 | 0.228 | 0 | 0 | 0.0 | 0 |
| IFNB1 | IFNB1 | P01574 | Interferon beta | chr9 | GO:0046649 | Not Cancer Driver | No | 46 | 0.246 | 0 | 0 | 0.0 | 0 |
| IFNE | IFNE | Q86WN2 | Interferon epsilon | chr9 | GO:0046649 | Not Cancer Driver | No | 30 | 0.144 | 17 | 4 | 0.235 | 0 |
| IFNK | IFNK | Q9P0W0 | Interferon kappa | chr9 | GO:0046649 | Not Cancer Driver | No | 17 | 0.082 | 23 | 0 | 0.0 | 0 |
| IFNW1 | IFNW1 | P05000 | Interferon omega-1 | chr9 | GO:0046649 | Not Cancer Driver | No | 32 | 0.164 | 10 | 3 | 0.3 | 0 |
| IL12B | IL12B | P29460 | Interleukin-12 subunit beta | chr5 | GO:0046649 | Not Cancer Driver | No | 48 | 0.146 | 42 | 2 | 0.048 | 0 |
| IL15_ENST00000320650 | IL15 | P40933 | Interleukin-15 | chr4 | GO:0046649 | Not Cancer Driver | No | 25 | 0.154 | 6 | 1 | 0.167 | 0 |
| IL18 | IL18 | Q14116 | Interleukin-18 | chr11 | GO:0046649 | Not Cancer Driver | No | 19 | 0.098 | 16 | 3 | 0.188 | 0 |
| IL18R1_ENST00000233957 | IL18R1 | Q13478 | Interleukin-18 receptor 1 | chr2 | GO:0046649 | Not Cancer Driver | No | 104 | 0.192 | 18 | 3 | 0.167 | 0 |
| IL2 | IL2 | P60568 | Interleukin-2 | chr4 | GO:0046649 | Census | Yes | 24 | 0.157 | 6 | 1 | 0.167 | 0 |
| IL21 | IL21 | Q9HBE4 | Interleukin-21 | chr4 | GO:0046649 | Not Cancer Driver | No | 34 | 0.21 | 70 | 18 | 0.257 | 1 |
| IL21R_ENST00000395754 | IL21R | Q9HBE5 | Interleukin-21 receptor | chr16 | GO:0046649 | Census | Yes | 133 | 0.247 | 183 | 47 | 0.257 | 1 |
| IL2RB | IL2RB | P14784 | Interleukin-2 receptor subunit beta | chr22 | GO:0046649 | Not Cancer Driver | No | 81 | 0.147 | 182 | 33 | 0.181 | 1 |
| IL4 | IL4 | P05112 | Interleukin-4 | chr5 | GO:0046649 | Not Cancer Driver | No | 18 | 0.118 | 0 | 0 | 0.0 | 0 |
| IL6 | IL6 | P05231 | Interleukin-6 | chr7 | GO:0046649 | Not Cancer Driver | No | 35 | 0.165 | 58 | 7 | 0.121 | 0 |
| INS | INS | P01308 | Insulin | chr11 | GO:0046649 | Not Cancer Driver | No | 15 | 0.136 | 5 | 1 | 0.2 | 22 |
| IRF1 | IRF1 | P10914 | Interferon regulatory factor 1 | chr5 | GO:0046649 | Compendium | Yes | 49 | 0.151 | 228 | 31 | 0.136 | 2 |
| IRF2BP2 | IRF2BP2 | Q7Z5L9 | Interferon regulatory factor 2-binding protein 2 | chr1 | GO:0046649 | Not Cancer Driver | No | 42 | 0.072 | 451 | 26 | 0.058 | 1 |
| IRF8 | IRF8 | Q02556 | Interferon regulatory factor 8 | chr16 | GO:0046649 | Not Cancer Driver | No | 80 | 0.188 | 77 | 20 | 0.26 | 2 |
| ITFG2 | ITFG2 | Q969R8 | KICSTOR complex protein ITFG2 | chr12 | GO:0046649 | Not Cancer Driver | No | 59 | 0.132 | 61 | 9 | 0.148 | 0 |
| ITGAL | ITGAL | P20701 | Integrin alpha-L | chr16 | GO:0046649 | Not Cancer Driver | No | 196 | 0.168 | 144 | 25 | 0.174 | 0 |
| ITK | ITK | Q08881 | Tyrosine-protein kinase ITK/TSK | chr5 | GO:0046649 | Census | Yes | 139 | 0.224 | 43 | 10 | 0.233 | 1 |
| ITM2A | ITM2A | O43736 | Integral membrane protein 2A | chrX | GO:0046649 | Not Cancer Driver | No | 75 | 0.285 | 26 | 9 | 0.346 | 0 |
| JAG2 | JAG2 | Q9Y219 | Protein jagged-2 | chr14 | GO:0046649 | Not Cancer Driver | No | 126 | 0.102 | 158 | 24 | 0.152 | 0 |
| JAML | JAML | Q86YT9 | Junctional adhesion molecule-like | chr11 | GO:0046649 | Not Cancer Driver | No | 72 | 0.183 | 68 | 11 | 0.162 | 0 |
| JMJD6_ENST00000397625 | JMJD6 | Q6NYC1 | Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 | chr17 | GO:0046649 | Not Cancer Driver | No | 51 | 0.127 | 133 | 21 | 0.158 | 0 |
| KAT7 | KAT7 | O95251 | Histone acetyltransferase KAT7 | chr17 | GO:0046649 | Census | Yes | 97 | 0.159 | 327 | 47 | 0.144 | 0 |
| KIT | KIT | P10721 | Mast/stem cell growth factor receptor Kit | chr4 | GO:0046649 | Census, Compendium | Yes | 226 | 0.232 | 83 | 33 | 0.398 | 21 |
| KLRC1 | KLRC1 | P26715 | NKG2-A/NKG2-B type II integral membrane protein | chr12 | GO:0046649 | Not Cancer Driver | No | 49 | 0.21 | 49 | 10 | 0.204 | 0 |
| KLRF2 | KLRF2 | D3W0D1 | Killer cell lectin-like receptor subfamily F member 2 | chr12 | GO:0046649 | Not Cancer Driver | No | 1 | 0.005 | 0 | 0 | 0.0 | 0 |
| KLRK1 | KLRK1 | P26718 | NKG2-D type II integral membrane protein | chr12 | GO:0046649 | Not Cancer Driver | No | 38 | 0.176 | 0 | 0 | 0.0 | 0 |
| LAX1 | LAX1 | Q8IWV1 | Lymphocyte transmembrane adapter 1 | chr1 | GO:0046649 | Not Cancer Driver | No | 61 | 0.153 | 228 | 32 | 0.14 | 0 |
| LEF1 | LEF1 | Q9UJU2 | Lymphoid enhancer-binding factor 1 | chr4 | GO:0046649 | Census | Yes | 64 | 0.16 | 370 | 57 | 0.154 | 0 |
| LFNG | LFNG | Q8NES3 | Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe | chr7 | GO:0046649 | Not Cancer Driver | No | 37 | 0.098 | 65 | 1 | 0.015 | 1 |
| LGALS1 | LGALS1 | P09382 | Galectin-1 | chr22 | GO:0046649 | Not Cancer Driver | No | 16 | 0.119 | 0 | 0 | 0.0 | 0 |
| LIG4 | LIG4 | P49917 | DNA ligase 4 | chr13 | GO:0046649 | Not Cancer Driver | No | 134 | 0.147 | 63 | 10 | 0.159 | 2 |
| LILRB1_ENST00000396331 | LILRB1 | Q8NHL6 | Leukocyte immunoglobulin-like receptor subfamily B member 1 | chr19 | GO:0046649 | Not Cancer Driver | No | 203 | 0.312 | 291 | 97 | 0.333 | 0 |
| LRRC8A_ENST00000372599 | LRRC8A | Q8IWT6 | Volume-regulated anion channel subunit LRRC8A | chr9 | GO:0046649 | Not Cancer Driver | No | 105 | 0.13 | 32 | 3 | 0.094 | 0 |
| MAFB | MAFB | Q9Y5Q3 | Transcription factor MafB | chr20 | GO:0046649 | Census | Yes | 35 | 0.108 | 301 | 34 | 0.113 | 10 |
| MALT1 | MALT1 | Q9UDY8 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | chr18 | GO:0046649 | Census, Compendium | Yes | 75 | 0.091 | 139 | 12 | 0.086 | 1 |
| MERTK_ENST00000421804 | MERTK | Q12866 | Tyrosine-protein kinase Mer | chr2 | GO:0046649 | Not Cancer Driver | No | 175 | 0.175 | 159 | 31 | 0.195 | 3 |
| MFNG | MFNG | O00587 | Beta-1,3-N-acetylglucosaminyltransferase manic fringe | chr22 | GO:0046649 | Not Cancer Driver | No | 37 | 0.115 | 29 | 4 | 0.138 | 0 |
| MICB | MICB | Q29980 | MHC class I polypeptide-related sequence B | chr6 | GO:0046649 | Not Cancer Driver | No | 56 | 0.146 | 175 | 22 | 0.126 | 0 |
| MLH1 | MLH1 | P40692 | DNA mismatch repair protein Mlh1 | chr3 | GO:0046649 | Census | Yes | 92 | 0.122 | 208 | 22 | 0.106 | 85 |
| MR1 | MR1 | Q95460 | Major histocompatibility complex class I-related gene protein | chr1 | GO:0046649 | Not Cancer Driver | No | 60 | 0.176 | 33 | 7 | 0.212 | 0 |
| MSH2 | MSH2 | P43246 | DNA mismatch repair protein Msh2 | chr2 | GO:0046649 | Census | Yes | 92 | 0.099 | 37 | 4 | 0.108 | 70 |
| MSH6 | MSH6 | P52701 | DNA mismatch repair protein Msh6 | chr2 | GO:0046649 | Census | Yes | 154 | 0.113 | 386 | 41 | 0.106 | 6 |
| NBN | NBN | O60934 | Nibrin | chr8 | GO:0046649 | Census | Yes | 90 | 0.119 | 417 | 54 | 0.129 | 1 |
| NCAPH2_ENST00000420993 | NCAPH2 | Q6IBW4 | Condensin-2 complex subunit H2 | chr22 | GO:0046649 | Not Cancer Driver | No | 67 | 0.111 | 335 | 39 | 0.116 | 0 |
| NCR1 | NCR1 | O76036 | Natural cytotoxicity triggering receptor 1 | chr19 | GO:0046649 | Not Cancer Driver | No | 81 | 0.266 | 27 | 8 | 0.296 | 0 |
| NCR3 | NCR3 | O14931 | Natural cytotoxicity triggering receptor 3 | chr6 | GO:0046649 | Not Cancer Driver | No | 26 | 0.129 | 31 | 2 | 0.065 | 0 |
| NFIL3 | NFIL3 | Q16649 | Nuclear factor interleukin-3-regulated protein | chr9 | GO:0046649 | Not Cancer Driver | No | 57 | 0.123 | 333 | 41 | 0.123 | 0 |
| NKAP | NKAP | Q8N5F7 | NF-kappa-B-activating protein | chrX | GO:0046649 | Not Cancer Driver | No | 80 | 0.193 | 409 | 77 | 0.188 | 3 |
| NKG7 | NKG7 | Q16617 | Protein NKG7 | chr19 | GO:0046649 | Not Cancer Driver | No | 34 | 0.206 | 0 | 0 | 0.0 | 0 |
| NKX2-3 | NKX2-3 | Q8TAU0 | Homeobox protein Nkx-2.3 | chr10 | GO:0046649 | Not Cancer Driver | No | 31 | 0.085 | 212 | 27 | 0.127 | 0 |
| NOTCH2 | NOTCH2 | Q04721 | Neurogenic locus notch homolog protein 2 | chr1 | GO:0046649 | Census, Compendium | Yes | 282 | 0.114 | 630 | 77 | 0.122 | 1 |
| PBX1 | PBX1 | P40424 | Pre-B-cell leukemia transcription factor 1 | chr1 | GO:0046649 | Census | Yes | 82 | 0.191 | 290 | 57 | 0.197 | 0 |
| PIK3CD | PIK3CD | O00329 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | chr1 | GO:0046649 | Not Cancer Driver | No | 140 | 0.134 | 60 | 13 | 0.217 | 1 |
| PLA2G2D | PLA2G2D | Q9UNK4 | Group IID secretory phospholipase A2 | chr1 | GO:0046649 | Not Cancer Driver | No | 27 | 0.186 | 0 | 0 | 0.0 | 0 |
| PLCG2 | PLCG2 | P16885 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | chr16 | GO:0046649 | Not Cancer Driver | No | 248 | 0.196 | 142 | 30 | 0.211 | 1 |
| PLCL2 | PLCL2 | Q9UPR0 | Inactive phospholipase C-like protein 2 | chr3 | GO:0046649 | Not Cancer Driver | No | 185 | 0.164 | 274 | 31 | 0.113 | 0 |
| POU2AF1 | POU2AF1 | Q16633 | POU domain class 2-associating factor 1 | chr11 | GO:0046649 | Census | Yes | 59 | 0.23 | 181 | 45 | 0.249 | 0 |
| PRDX1_ENST00000319248 | PRDX1 | Q06830 | Peroxiredoxin-1 | chr1 | GO:0046649 | Not Cancer Driver | No | 22 | 0.111 | 40 | 5 | 0.125 | 0 |
| PRKDC | PRKDC | P78527 | DNA-dependent protein kinase catalytic subunit | chr8 | GO:0046649 | Not Cancer Driver | No | 538 | 0.13 | 421 | 61 | 0.145 | 2 |
| PRR7_ENST00000502922 | PRR7 | Q8TB68 | Proline-rich protein 7 | chr5 | GO:0046649 | Not Cancer Driver | No | 10 | 0.036 | 199 | 6 | 0.03 | 0 |
| PSMB11 | PSMB11 | A5LHX3 | Proteasome subunit beta type-11 | chr14 | GO:0046649 | Not Cancer Driver | No | 62 | 0.207 | 71 | 11 | 0.155 | 0 |
| PTGER4 | PTGER4 | P35408 | Prostaglandin E2 receptor EP4 subtype | chr5 | GO:0046649 | Not Cancer Driver | No | 81 | 0.166 | 118 | 17 | 0.144 | 0 |
| PTK2B_ENST00000346049 | PTK2B | Q14289 | Protein-tyrosine kinase 2-beta | chr8 | GO:0046649 | Not Cancer Driver | No | 161 | 0.16 | 261 | 37 | 0.142 | 0 |
| PTPRC | PTPRC | P08575 | Receptor-type tyrosine-protein phosphatase C | chr1 | GO:0046649 | Census, Compendium | Yes | 315 | 0.241 | 462 | 107 | 0.232 | 0 |
| RAB27A_ENST00000336787 | RAB27A | P51159 | Ras-related protein Rab-27A | chr15 | GO:0046649 | Not Cancer Driver | No | 25 | 0.113 | 15 | 4 | 0.267 | 3 |
| RABL3 | RABL3 | Q5HYI8 | Rab-like protein 3 | chr3 | GO:0046649 | Not Cancer Driver | No | 37 | 0.157 | 1 | 0 | 0.0 | 1 |
| RAG1 | RAG1 | P15918 | V(D)J recombination-activating protein 1 | chr11 | GO:0046649 | Not Cancer Driver | No | 204 | 0.196 | 208 | 43 | 0.207 | 36 |
| RAG2 | RAG2 | P55895 | V(D)J recombination-activating protein 2 | chr11 | GO:0046649 | Not Cancer Driver | No | 118 | 0.224 | 85 | 23 | 0.271 | 6 |
| RASGRP1 | RASGRP1 | O95267 | RAS guanyl-releasing protein 1 | chr15 | GO:0046649 | Not Cancer Driver | No | 96 | 0.12 | 191 | 12 | 0.063 | 1 |
| RC3H1_ENST00000258349 | RC3H1 | Q5TC82 | Roquin-1 | chr1 | GO:0046649 | Not Cancer Driver | No | 158 | 0.139 | 796 | 115 | 0.144 | 0 |
| RC3H2_ENST00000357244 | RC3H2 | Q9HBD1 | Roquin-2 | chr9 | GO:0046649 | Not Cancer Driver | No | 128 | 0.107 | 703 | 81 | 0.115 | 0 |
| RELB | RELB | Q01201 | Transcription factor RelB | chr19 | GO:0046649 | Not Cancer Driver | No | 65 | 0.112 | 348 | 39 | 0.112 | 0 |
| RIPK3 | RIPK3 | Q9Y572 | Receptor-interacting serine/threonine-protein kinase 3 | chr14 | GO:0046649 | Not Cancer Driver | No | 66 | 0.127 | 295 | 39 | 0.132 | 0 |
| RNF168 | RNF168 | Q8IYW5 | E3 ubiquitin-protein ligase RNF168 | chr3 | GO:0046649 | Not Cancer Driver | No | 77 | 0.135 | 471 | 66 | 0.14 | 0 |
| RNF8 | RNF8 | O76064 | E3 ubiquitin-protein ligase RNF8 | chr6 | GO:0046649 | Not Cancer Driver | No | 56 | 0.115 | 226 | 29 | 0.128 | 0 |
| RORA_ENST00000335670 | RORA | P35398 | Nuclear receptor ROR-alpha | chr15 | GO:0046649 | Not Cancer Driver | No | 57 | 0.109 | 182 | 17 | 0.093 | 4 |
| RORC | RORC | P51449 | Nuclear receptor ROR-gamma | chr1 | GO:0046649 | Not Cancer Driver | No | 96 | 0.185 | 187 | 36 | 0.193 | 1 |
| RPS6 | RPS6 | P62753 | 40S ribosomal protein S6 | chr9 | GO:0046649 | Not Cancer Driver | No | 38 | 0.153 | 150 | 25 | 0.167 | 0 |
| RSAD2 | RSAD2 | Q8WXG1 | Radical S-adenosyl methionine domain-containing protein 2 | chr2 | GO:0046649 | Not Cancer Driver | No | 68 | 0.188 | 22 | 1 | 0.045 | 0 |
| SEMA4A_ENST00000355014 | SEMA4A | Q9H3S1 | Semaphorin-4A | chr1 | GO:0046649 | Not Cancer Driver | No | 123 | 0.162 | 122 | 26 | 0.213 | 4 |
| SHH | SHH | Q15465 | Sonic hedgehog protein | chr7 | GO:0046649 | Not Cancer Driver | No | 56 | 0.121 | 139 | 14 | 0.101 | 81 |
| SLAMF1_ENST00000302035 | SLAMF1 | Q13291 | Signaling lymphocytic activation molecule | chr1 | GO:0046649 | Not Cancer Driver | No | 82 | 0.245 | 64 | 10 | 0.156 | 0 |
| SLAMF7 | SLAMF7 | Q9NQ25 | SLAM family member 7 | chr1 | GO:0046649 | Not Cancer Driver | No | 66 | 0.197 | 53 | 14 | 0.264 | 0 |
| SLC11A1 | SLC11A1 | P49279 | Natural resistance-associated macrophage protein 1 | chr2 | GO:0046649 | Not Cancer Driver | No | 79 | 0.144 | 47 | 5 | 0.106 | 0 |
| SOX13 | SOX13 | Q9UN79 | Transcription factor SOX-13 | chr1 | GO:0046649 | Not Cancer Driver | No | 85 | 0.137 | 564 | 77 | 0.137 | 0 |
| SP3 | SP3 | Q02447 | Transcription factor Sp3 | chr2 | GO:0046649 | Not Cancer Driver | No | 66 | 0.085 | 587 | 37 | 0.063 | 0 |
| SPI1_ENST00000378538 | SPI1 | P17947 | Transcription factor PU.1 | chr11 | GO:0046649 | Not Cancer Driver | No | 46 | 0.17 | 187 | 34 | 0.182 | 0 |
| ST3GAL1_ENST00000522652 | ST3GAL1 | Q11201 | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 | chr8 | GO:0046649 | Not Cancer Driver | No | 51 | 0.15 | 6 | 0 | 0.0 | 0 |
| STAT5B | STAT5B | P51692 | Signal transducer and activator of transcription 5B | chr17 | GO:0046649 | Census, Compendium | Yes | 93 | 0.118 | 144 | 19 | 0.132 | 5 |
| STOML2 | STOML2 | Q9UJZ1 | Stomatin-like protein 2, mitochondrial | chr9 | GO:0046649 | Not Cancer Driver | No | 40 | 0.112 | 117 | 9 | 0.077 | 0 |
| SWAP70 | SWAP70 | Q9UH65 | Switch-associated protein 70 | chr11 | GO:0046649 | Not Cancer Driver | No | 44 | 0.075 | 271 | 18 | 0.066 | 0 |
| SYVN1 | SYVN1 | Q86TM6 | E3 ubiquitin-protein ligase synoviolin | chr11 | GO:0046649 | Not Cancer Driver | No | 63 | 0.102 | 284 | 32 | 0.113 | 0 |
| TBK1 | TBK1 | Q9UHD2 | Serine/threonine-protein kinase TBK1 | chr12 | GO:0046649 | Not Cancer Driver | No | 101 | 0.139 | 42 | 5 | 0.119 | 12 |
| TCIRG1 | TCIRG1 | Q13488 | V-type proton ATPase 116 kDa subunit a 3 | chr11 | GO:0046649 | Compendium | Yes | 68 | 0.082 | 102 | 6 | 0.059 | 5 |
| TESPA1 | TESPA1 | A2RU30 | Protein TESPA1 | chr12 | GO:0046649 | Not Cancer Driver | No | 127 | 0.244 | 284 | 84 | 0.296 | 0 |
| TLR4_ENST00000355622 | TLR4 | O00206 | Toll-like receptor 4 | chr9 | GO:0046649 | Not Cancer Driver | No | 292 | 0.348 | 0 | 0 | 0.0 | 0 |
| TMEM98 | TMEM98 | Q9Y2Y6 | Transmembrane protein 98 | chr17 | GO:0046649 | Not Cancer Driver | No | 39 | 0.173 | 27 | 3 | 0.111 | 2 |
| TNFSF4 | TNFSF4 | P23510 | Tumor necrosis factor ligand superfamily member 4 | chr1 | GO:0046649 | Not Cancer Driver | No | 28 | 0.153 | 1 | 0 | 0.0 | 0 |
| TNFSF8 | TNFSF8 | P32971 | Tumor necrosis factor ligand superfamily member 8 | chr9 | GO:0046649 | Not Cancer Driver | No | 34 | 0.145 | 30 | 2 | 0.067 | 0 |
| TOX | TOX | O94900 | Thymocyte selection-associated high mobility group box protein TOX | chr8 | GO:0046649 | Not Cancer Driver | No | 112 | 0.213 | 494 | 108 | 0.219 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0046649 | Census, Compendium | Yes | 2891 | 7.356 | 282 | 1466 | 5.199 | 83 |
| TRAF3IP2_ENST00000392556 | TRAF3IP2 | O43734 | E3 ubiquitin ligase TRAF3IP2 | chr6 | GO:0046649 | Not Cancer Driver | No | 59 | 0.103 | 410 | 39 | 0.095 | 2 |
| TSC1 | TSC1 | Q92574 | Hamartin | chr9 | GO:0046649 | Census, Compendium | Yes | 135 | 0.116 | 732 | 78 | 0.107 | 11 |
| TUSC2 | TUSC2 | O75896 | Tumor suppressor candidate 2 | chr3 | GO:0046649 | Not Cancer Driver | No | 10 | 0.091 | 31 | 3 | 0.097 | 0 |
| TYRO3 | TYRO3 | Q06418 | Tyrosine-protein kinase receptor TYRO3 | chr15 | GO:0046649 | Not Cancer Driver | No | 119 | 0.134 | 197 | 17 | 0.086 | 0 |
| ULBP1 | ULBP1 | Q9BZM6 | UL16-binding protein 1 | chr6 | GO:0046649 | Not Cancer Driver | No | 48 | 0.197 | 24 | 4 | 0.167 | 0 |
| ULBP2 | ULBP2 | Q9BZM5 | UL16-binding protein 2 | chr6 | GO:0046649 | Not Cancer Driver | No | 33 | 0.134 | 25 | 2 | 0.08 | 0 |
| ULBP3 | ULBP3 | Q9BZM4 | UL16-binding protein 3 | chr6 | GO:0046649 | Not Cancer Driver | No | 34 | 0.139 | 14 | 1 | 0.071 | 0 |
| UNC13D | UNC13D | Q70J99 | Protein unc-13 homolog D | chr17 | GO:0046649 | Not Cancer Driver | No | 120 | 0.11 | 248 | 30 | 0.121 | 0 |
| UNG | UNG | P13051 | Uracil-DNA glycosylase | chr12 | GO:0046649 | Not Cancer Driver | No | 34 | 0.109 | 96 | 13 | 0.135 | 1 |
| VAMP2_ENST00000316509 | VAMP2 | P63027 | Vesicle-associated membrane protein 2 | chr17 | GO:0046649 | Not Cancer Driver | No | 7 | 0.06 | 47 | 4 | 0.085 | 3 |
| VAMP7_ENST00000286448 | VAMP7 | P51809 | Vesicle-associated membrane protein 7 | chrX | GO:0046649 | Not Cancer Driver | No | 38 | 0.173 | 4 | 1 | 0.25 | 0 |
| WDFY4 | WDFY4 | Q6ZS81 | WD repeat- and FYVE domain-containing protein 4 | chr10 | GO:0046649 | Not Cancer Driver | No | 217 | 0.068 | 475 | 36 | 0.076 | 0 |
| WNT1 | WNT1 | P04628 | Proto-oncogene Wnt-1 | chr12 | GO:0046649 | Not Cancer Driver | No | 29 | 0.078 | 25 | 0 | 0.0 | 8 |
| WNT4 | WNT4 | P56705 | Protein Wnt-4 | chr1 | GO:0046649 | Not Cancer Driver | No | 30 | 0.085 | 39 | 4 | 0.103 | 4 |
| ZBTB7B_ENST00000368426 | ZBTB7B | O15156 | Zinc finger and BTB domain-containing protein 7B | chr1 | GO:0046649 | Compendium | Yes | 103 | 0.191 | 353 | 70 | 0.198 | 0 |
| ZFP36L1 | ZFP36L1 | Q07352 | mRNA decay activator protein ZFP36L1 | chr14 | GO:0046649 | Compendium | Yes | 57 | 0.169 | 212 | 30 | 0.142 | 0 |
| ZFP36L2 | ZFP36L2 | P47974 | mRNA decay activator protein ZFP36L2 | chr2 | GO:0046649 | Not Cancer Driver | No | 73 | 0.148 | 324 | 45 | 0.139 | 0 |