Total number of protein in "GO:0046580" GO term: 50
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABL2 | ABL2 | P42684 | Tyrosine-protein kinase ABL2 | chr1 | GO:0046580 | Census, Compendium | Yes | 171 | 0.145 | 641 | 70 | 0.109 | 0 |
| ADRA1A_ENST00000380573 | ADRA1A | P35348 | Alpha-1A adrenergic receptor | chr8 | GO:0046580 | Not Cancer Driver | No | 130 | 0.279 | 40 | 8 | 0.2 | 0 |
| ARHGAP24 | ARHGAP24 | Q8N264 | Rho GTPase-activating protein 24 | chr4 | GO:0046580 | Not Cancer Driver | No | 103 | 0.138 | 482 | 67 | 0.139 | 0 |
| ARHGAP35_ENST00000614079 | ARHGAP35 | Q9NRY4 | Rho GTPase-activating protein 35 | chr19 | GO:0046580 | Census, Compendium | Yes | 255 | 0.17 | 409 | 58 | 0.142 | 0 |
| ARHGAP42 | ARHGAP42 | A6NI28 | Rho GTPase-activating protein 42 | chr11 | GO:0046580 | Not Cancer Driver | No | 63 | 0.072 | 311 | 17 | 0.055 | 0 |
| ARHGAP44 | ARHGAP44 | Q17R89 | Rho GTPase-activating protein 44 | chr17 | GO:0046580 | Not Cancer Driver | No | 126 | 0.154 | 424 | 67 | 0.158 | 0 |
| BCL6_ENST00000232014 | BCL6 | P41182 | B-cell lymphoma 6 protein | chr3 | GO:0046580 | Census, Compendium | Yes | 134 | 0.19 | 328 | 67 | 0.204 | 0 |
| CCDC125_ENST00000396499 | CCDC125 | Q86Z20 | Coiled-coil domain-containing protein 125 | chr5 | GO:0046580 | Not Cancer Driver | No | 58 | 0.114 | 261 | 23 | 0.088 | 0 |
| CUL3 | CUL3 | Q13618 | Cullin-3 | chr2 | GO:0046580 | Census, Compendium | Yes | 123 | 0.16 | 167 | 23 | 0.138 | 3 |
| DAB2IP_ENST00000408936 | DAB2IP | Q5VWQ8 | Disabled homolog 2-interacting protein | chr9 | GO:0046580 | Not Cancer Driver | No | 131 | 0.11 | 681 | 68 | 0.1 | 0 |
| DLC1 | DLC1 | Q96QB1 | Rho GTPase-activating protein 7 | chr8 | GO:0046580 | Not Cancer Driver | No | 331 | 0.217 | 922 | 237 | 0.257 | 0 |
| EPHB2 | EPHB2 | P29323 | Ephrin type-B receptor 2 | chr1 | GO:0046580 | Not Cancer Driver | No | 186 | 0.176 | 119 | 17 | 0.143 | 7 |
| FBP1_ENST00000375326 | FBP1 | P09467 | Fructose-1,6-bisphosphatase 1 | chr9 | GO:0046580 | Not Cancer Driver | No | 33 | 0.098 | 19 | 0 | 0.0 | 4 |
| FLCN | FLCN | Q8NFG4 | Folliculin | chr17 | GO:0046580 | Census, Compendium | Yes | 59 | 0.102 | 157 | 19 | 0.121 | 5 |
| HEG1 | HEG1 | Q9ULI3 | Protein HEG homolog 1 | chr3 | GO:0046580 | Not Cancer Driver | No | 173 | 0.125 | 974 | 135 | 0.139 | 0 |
| ITGA3 | ITGA3 | P26006 | Integrin alpha-3 | chr17 | GO:0046580 | Not Cancer Driver | No | 106 | 0.101 | 129 | 18 | 0.14 | 3 |
| ITGB1_ENST00000302278 | ITGB1 | P05556 | Integrin beta-1 | chr10 | GO:0046580 | Not Cancer Driver | No | 103 | 0.129 | 84 | 10 | 0.119 | 0 |
| KANK1_ENST00000382303 | KANK1 | Q14678 | KN motif and ankyrin repeat domain-containing protein 1 | chr9 | GO:0046580 | Not Cancer Driver | No | 183 | 0.135 | 804 | 100 | 0.124 | 0 |
| KCTD10 | KCTD10 | Q9H3F6 | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 | chr12 | GO:0046580 | Not Cancer Driver | No | 68 | 0.217 | 73 | 19 | 0.26 | 0 |
| KCTD13 | KCTD13 | Q8WZ19 | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 | chr16 | GO:0046580 | Not Cancer Driver | No | 33 | 0.1 | 95 | 10 | 0.105 | 0 |
| LZTR1_ENST00000646124 | LZTR1 | Q8N653 | Leucine-zipper-like transcriptional regulator 1 | chr22 | GO:0046580 | Census, Compendium | Yes | 160 | 0.19 | 106 | 18 | 0.17 | 26 |
| MAPKAP1 | MAPKAP1 | Q9BPZ7 | Target of rapamycin complex 2 subunit MAPKAP1 | chr9 | GO:0046580 | Not Cancer Driver | No | 70 | 0.134 | 173 | 25 | 0.145 | 0 |
| MET_ENST00000397752 | MET | P08581 | Hepatocyte growth factor receptor | chr7 | GO:0046580 | Census, Compendium | Yes | 226 | 0.163 | 62 | 15 | 0.242 | 19 |
| MFN2_ENST00000444836 | MFN2 | O95140 | Mitofusin-2 | chr1 | GO:0046580 | Not Cancer Driver | No | 80 | 0.106 | 81 | 9 | 0.111 | 20 |
| MYOC | MYOC | Q99972 | Myocilin | chr1 | GO:0046580 | Not Cancer Driver | No | 92 | 0.183 | 196 | 43 | 0.219 | 58 |
| NF1 | NF1 | P21359 | Neurofibromin | chr17 | GO:0046580 | Census, Compendium | Yes | 375 | 0.132 | 406 | 47 | 0.116 | 85 |
| NUP62 | NUP62 | P37198 | Nuclear pore glycoprotein p62 | chr19 | GO:0046580 | Not Cancer Driver | No | 76 | 0.146 | 377 | 56 | 0.149 | 1 |
| PPP2CB | PPP2CB | P62714 | Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform | chr8 | GO:0046580 | Not Cancer Driver | No | 37 | 0.12 | 12 | 0 | 0.0 | 0 |
| RABGEF1_ENST00000284957 | RABGEF1 | Q9UJ41 | Rab5 GDP/GTP exchange factor | chr7 | GO:0046580 | Not Cancer Driver | No | 73 | 0.149 | 175 | 35 | 0.2 | 0 |
| RASA1 | RASA1 | P20936 | Ras GTPase-activating protein 1 | chr5 | GO:0046580 | Compendium | Yes | 154 | 0.147 | 181 | 25 | 0.138 | 3 |
| RASA2 | RASA2 | Q15283 | Ras GTPase-activating protein 2 | chr3 | GO:0046580 | Compendium | Yes | 104 | 0.122 | 142 | 19 | 0.134 | 0 |
| RASA3 | RASA3 | Q14644 | Ras GTPase-activating protein 3 | chr13 | GO:0046580 | Not Cancer Driver | No | 118 | 0.141 | 101 | 19 | 0.188 | 0 |
| RASA4 | RASA4 | O43374 | Ras GTPase-activating protein 4 | chr7 | GO:0046580 | Not Cancer Driver | No | 14 | 0.017 | 164 | 3 | 0.018 | 0 |
| RASA4B_ENST00000465829 | RASA4B | C9J798 | Ras GTPase-activating protein 4B | chr7 | GO:0046580 | Not Cancer Driver | No | 13 | 0.016 | 157 | 1 | 0.006 | 0 |
| RASAL1_ENST00000261729 | RASAL1 | O95294 | RasGAP-activating-like protein 1 | chr12 | GO:0046580 | Not Cancer Driver | No | 132 | 0.164 | 106 | 25 | 0.236 | 0 |
| RASAL3 | RASAL3 | Q86YV0 | RAS protein activator like-3 | chr19 | GO:0046580 | Not Cancer Driver | No | 114 | 0.113 | 536 | 68 | 0.127 | 0 |
| RASIP1 | RASIP1 | Q5U651 | Ras-interacting protein 1 | chr19 | GO:0046580 | Not Cancer Driver | No | 73 | 0.076 | 505 | 48 | 0.095 | 0 |
| RIPOR2_ENST00000259698 | RIPOR2 | Q9Y4F9 | Rho family-interacting cell polarization regulator 2 | chr6 | GO:0046580 | Not Cancer Driver | No | 131 | 0.123 | 421 | 76 | 0.181 | 0 |
| SCAI_ENST00000336505 | SCAI | Q8N9R8 | Protein SCAI | chr9 | GO:0046580 | Not Cancer Driver | No | 95 | 0.157 | 117 | 13 | 0.111 | 0 |
| SPRY1 | SPRY1 | O43609 | Protein sprouty homolog 1 | chr4 | GO:0046580 | Not Cancer Driver | No | 46 | 0.144 | 168 | 26 | 0.155 | 0 |
| SPRY2 | SPRY2 | O43597 | Protein sprouty homolog 2 | chr13 | GO:0046580 | Not Cancer Driver | No | 46 | 0.146 | 169 | 29 | 0.172 | 1 |
| SPRY3 | SPRY3 | O43610 | Protein sprouty homolog 3 | chrX | GO:0046580 | Not Cancer Driver | No | 96 | 0.333 | 135 | 40 | 0.296 | 0 |
| SPRY4_ENST00000434127 | SPRY4 | Q9C004 | Protein sprouty homolog 4 | chr5 | GO:0046580 | Not Cancer Driver | No | 34 | 0.114 | 134 | 20 | 0.149 | 7 |
| STAMBP_ENST00000339566 | STAMBP | O95630 | STAM-binding protein | chr2 | GO:0046580 | Not Cancer Driver | No | 51 | 0.12 | 139 | 16 | 0.115 | 6 |
| STMN1_ENST00000357865 | STMN1 | P16949 | Stathmin | chr1 | GO:0046580 | Not Cancer Driver | No | 15 | 0.101 | 149 | 15 | 0.101 | 0 |
| STMN3 | STMN3 | Q9NZ72 | Stathmin-3 | chr20 | GO:0046580 | Not Cancer Driver | No | 26 | 0.144 | 152 | 25 | 0.164 | 0 |
| SYNGAP1_ENST00000646630 | SYNGAP1 | Q96PV0 | Ras/Rap GTPase-activating protein SynGAP | chr6 | GO:0046580 | Not Cancer Driver | No | 153 | 0.114 | 830 | 90 | 0.108 | 2 |
| TGFB2_ENST00000366930 | TGFB2 | P61812 | Transforming growth factor beta-2 proprotein | chr1 | GO:0046580 | Not Cancer Driver | No | 63 | 0.152 | 47 | 8 | 0.17 | 3 |
| TNFAIP1 | TNFAIP1 | Q13829 | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 | chr17 | GO:0046580 | Not Cancer Driver | No | 35 | 0.111 | 39 | 5 | 0.128 | 0 |
| TRIM67 | TRIM67 | Q6ZTA4 | Tripartite motif-containing protein 67 | chr1 | GO:0046580 | Not Cancer Driver | No | 128 | 0.163 | 230 | 17 | 0.074 | 0 |