Total number of protein in "GO:0046579" GO term: 61
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABRA | ABRA | Q8N0Z2 | Actin-binding Rho-activating protein | chr8 | GO:0046579 | Not Cancer Driver | No | 108 | 0.283 | 285 | 86 | 0.302 | 0 |
| ADGRG1 | ADGRG1 | Q9Y653 | Adhesion G-protein coupled receptor G1 | chr16 | GO:0046579 | Not Cancer Driver | No | 64 | 0.092 | 67 | 4 | 0.06 | 9 |
| AKAP13_ENST00000394518 | AKAP13 | Q12802 | A-kinase anchor protein 13 | chr15 | GO:0046579 | Not Cancer Driver | No | 359 | 0.128 | 2091 | 258 | 0.123 | 0 |
| ALS2 | ALS2 | Q96Q42 | Alsin | chr2 | GO:0046579 | Not Cancer Driver | No | 194 | 0.117 | 353 | 36 | 0.102 | 0 |
| APOA1_ENST00000375320 | APOA1 | P02647 | Apolipoprotein A-I | chr11 | GO:0046579 | Not Cancer Driver | No | 28 | 0.105 | 131 | 8 | 0.061 | 3 |
| ARHGEF3_ENST00000296315 | ARHGEF3 | Q9NR81 | Rho guanine nucleotide exchange factor 3 | chr3 | GO:0046579 | Not Cancer Driver | No | 70 | 0.133 | 154 | 17 | 0.11 | 0 |
| ARRB1 | ARRB1 | P49407 | Beta-arrestin-1 | chr11 | GO:0046579 | Not Cancer Driver | No | 49 | 0.117 | 154 | 13 | 0.084 | 0 |
| AUTS2 | AUTS2 | Q8WXX7 | Autism susceptibility gene 2 protein | chr7 | GO:0046579 | Not Cancer Driver | No | 219 | 0.174 | 1218 | 213 | 0.175 | 0 |
| COL3A1 | COL3A1 | P02461 | Collagen alpha-1(III) chain | chr2 | GO:0046579 | Census | Yes | 402 | 0.274 | 1182 | 337 | 0.285 | 103 |
| CSF1_ENST00000369802 | CSF1 | P09603 | Macrophage colony-stimulating factor 1 | chr1 | GO:0046579 | Not Cancer Driver | No | 69 | 0.125 | 339 | 46 | 0.136 | 0 |
| EPO | EPO | P01588 | Erythropoietin | chr7 | GO:0046579 | Not Cancer Driver | No | 27 | 0.14 | 9 | 1 | 0.111 | 1 |
| ERBIN_ENST00000284037 | ERBIN | Q96RT1 | Erbin | chr5 | GO:0046579 | Not Cancer Driver | No | 167 | 0.118 | 967 | 118 | 0.122 | 0 |
| F11R | F11R | Q9Y624 | Junctional adhesion molecule A | chr1 | GO:0046579 | Not Cancer Driver | No | 47 | 0.157 | 72 | 15 | 0.208 | 0 |
| F2R | F2R | P25116 | Proteinase-activated receptor 1 | chr5 | GO:0046579 | Not Cancer Driver | No | 73 | 0.172 | 19 | 2 | 0.105 | 0 |
| F2RL1 | F2RL1 | P55085 | Proteinase-activated receptor 2 | chr5 | GO:0046579 | Not Cancer Driver | No | 55 | 0.139 | 7 | 2 | 0.286 | 0 |
| F2RL2 | F2RL2 | O00254 | Proteinase-activated receptor 3 | chr5 | GO:0046579 | Not Cancer Driver | No | 54 | 0.144 | 0 | 0 | 0.0 | 0 |
| F2RL3 | F2RL3 | Q96RI0 | Proteinase-activated receptor 4 | chr19 | GO:0046579 | Not Cancer Driver | No | 43 | 0.112 | 46 | 4 | 0.087 | 0 |
| FGF10 | FGF10 | O15520 | Fibroblast growth factor 10 | chr5 | GO:0046579 | Not Cancer Driver | No | 56 | 0.269 | 34 | 11 | 0.324 | 2 |
| GPR17 | GPR17 | Q13304 | Uracil nucleotide/cysteinyl leukotriene receptor | chr2 | GO:0046579 | Not Cancer Driver | No | 57 | 0.155 | 16 | 4 | 0.25 | 0 |
| GPR174_ENST00000276077 | GPR174 | Q9BXC1 | Probable G-protein coupled receptor 174 | chrX | GO:0046579 | Not Cancer Driver | No | 115 | 0.345 | 0 | 0 | 0.0 | 0 |
| GPR18_ENST00000397470 | GPR18 | Q14330 | N-arachidonyl glycine receptor | chr13 | GO:0046579 | Not Cancer Driver | No | 36 | 0.109 | 0 | 0 | 0.0 | 0 |
| GPR20 | GPR20 | Q99678 | G-protein coupled receptor 20 | chr8 | GO:0046579 | Not Cancer Driver | No | 77 | 0.215 | 44 | 11 | 0.25 | 0 |
| GPR35_ENST00000403859 | GPR35 | Q9HC97 | G-protein coupled receptor 35 | chr2 | GO:0046579 | Not Cancer Driver | No | 57 | 0.184 | 0 | 0 | 0.0 | 0 |
| GPR4 | GPR4 | P46093 | G-protein coupled receptor 4 | chr19 | GO:0046579 | Not Cancer Driver | No | 57 | 0.157 | 44 | 8 | 0.182 | 0 |
| GPR55 | GPR55 | Q9Y2T6 | G-protein coupled receptor 55 | chr2 | GO:0046579 | Not Cancer Driver | No | 64 | 0.201 | 0 | 0 | 0.0 | 0 |
| GPR65 | GPR65 | Q8IYL9 | Psychosine receptor | chr14 | GO:0046579 | Not Cancer Driver | No | 70 | 0.208 | 0 | 0 | 0.0 | 0 |
| IGF1_ENST00000307046 | IGF1 | P05019 | Insulin-like growth factor I | chr12 | GO:0046579 | Not Cancer Driver | No | 45 | 0.231 | 87 | 23 | 0.264 | 0 |
| ITPKB_ENST00000272117 | ITPKB | P27987 | Inositol-trisphosphate 3-kinase B | chr1 | GO:0046579 | Not Cancer Driver | No | 148 | 0.156 | 719 | 119 | 0.166 | 0 |
| KITLG | KITLG | P21583 | Kit ligand | chr12 | GO:0046579 | Not Cancer Driver | No | 48 | 0.176 | 61 | 9 | 0.148 | 1 |
| KRAS | KRAS | P01116 | GTPase KRas | chr12 | GO:0046579 | Census, Compendium | Yes | 788 | 4.169 | 7 | 2 | 0.286 | 27 |
| LPAR1_ENST00000358883 | LPAR1 | Q92633 | Lysophosphatidic acid receptor 1 | chr9 | GO:0046579 | Not Cancer Driver | No | 79 | 0.217 | 21 | 6 | 0.286 | 0 |
| LPAR4 | LPAR4 | Q99677 | Lysophosphatidic acid receptor 4 | chrX | GO:0046579 | Compendium | Yes | 123 | 0.332 | 10 | 3 | 0.3 | 0 |
| LPAR6_ENST00000620633 | LPAR6 | P43657 | Lysophosphatidic acid receptor 6 | chr13 | GO:0046579 | Not Cancer Driver | No | 39 | 0.113 | 0 | 0 | 0.0 | 3 |
| LRRC59 | LRRC59 | Q96AG4 | Leucine-rich repeat-containing protein 59 | chr17 | GO:0046579 | Not Cancer Driver | No | 33 | 0.107 | 122 | 15 | 0.123 | 0 |
| LRRD1_ENST00000430130 | LRRD1 | A4D1F6 | Leucine-rich repeat and death domain-containing protein 1 | chr7 | GO:0046579 | Not Cancer Driver | No | 69 | 0.08 | 132 | 12 | 0.091 | 0 |
| MAP4K4_ENST00000347699 | MAP4K4 | O95819 | Mitogen-activated protein kinase kinase kinase kinase 4 | chr2 | GO:0046579 | Not Cancer Driver | No | 143 | 0.115 | 649 | 55 | 0.085 | 0 |
| MAPRE2 | MAPRE2 | Q15555 | Microtubule-associated protein RP/EB family member 2 | chr18 | GO:0046579 | Not Cancer Driver | No | 50 | 0.153 | 176 | 28 | 0.159 | 3 |
| MCF2L_ENST00000375608 | MCF2L | O15068 | Guanine nucleotide exchange factor DBS | chr13 | GO:0046579 | Not Cancer Driver | No | 173 | 0.152 | 410 | 54 | 0.132 | 0 |
| MMD2 | MMD2 | Q8IY49 | Monocyte to macrophage differentiation factor 2 | chr7 | GO:0046579 | Not Cancer Driver | No | 58 | 0.215 | 0 | 0 | 0.0 | 0 |
| NET1 | NET1 | Q7Z628 | Neuroepithelial cell-transforming gene 1 protein | chr10 | GO:0046579 | Not Cancer Driver | No | 60 | 0.101 | 294 | 37 | 0.126 | 0 |
| NGF | NGF | P01138 | Beta-nerve growth factor | chr1 | GO:0046579 | Not Cancer Driver | No | 66 | 0.274 | 93 | 25 | 0.269 | 1 |
| NOTCH1 | NOTCH1 | P46531 | Neurogenic locus notch homolog protein 1 | chr9 | GO:0046579 | Census, Compendium | Yes | 363 | 0.142 | 686 | 87 | 0.127 | 3 |
| NOTCH2 | NOTCH2 | Q04721 | Neurogenic locus notch homolog protein 2 | chr1 | GO:0046579 | Census, Compendium | Yes | 282 | 0.114 | 630 | 77 | 0.122 | 1 |
| NRG1_ENST00000405005 | NRG1 | Q02297 | Pro-neuregulin-1, membrane-bound isoform | chr8 | GO:0046579 | Census, Compendium | Yes | 159 | 0.248 | 528 | 132 | 0.25 | 0 |
| NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | GO:0046579 | Census, Compendium | Yes | 168 | 0.211 | 57 | 8 | 0.14 | 25 |
| P2RY10 | P2RY10 | O00398 | Putative P2Y purinoceptor 10 | chrX | GO:0046579 | Not Cancer Driver | No | 113 | 0.333 | 0 | 0 | 0.0 | 0 |
| P2RY8 | P2RY8 | Q86VZ1 | P2Y purinoceptor 8 | chrX | GO:0046579 | Census, Compendium | Yes | 126 | 0.351 | 23 | 5 | 0.217 | 0 |
| PDGFRB | PDGFRB | P09619 | Platelet-derived growth factor receptor beta | chr5 | GO:0046579 | Census, Compendium | Yes | 164 | 0.148 | 231 | 44 | 0.19 | 7 |
| PIK3CB_ENST00000477593 | PIK3CB | P42338 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | chr3 | GO:0046579 | Census, Compendium | Yes | 150 | 0.14 | 42 | 4 | 0.095 | 0 |
| PIK3CG | PIK3CG | P48736 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | chr7 | GO:0046579 | Not Cancer Driver | No | 318 | 0.289 | 121 | 39 | 0.322 | 0 |
| PRAG1_ENST00000622241 | PRAG1 | Q86YV5 | Inactive tyrosine-protein kinase PRAG1 | chr8 | GO:0046579 | Not Cancer Driver | No | 193 | 0.137 | 988 | 150 | 0.152 | 0 |
| RAC1_ENST00000348035 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | GO:0046579 | Census, Compendium | Yes | 66 | 0.344 | 2 | 1 | 0.5 | 6 |
| RASGEF1A_ENST00000395810 | RASGEF1A | Q8N9B8 | Ras-GEF domain-containing family member 1A | chr10 | GO:0046579 | Not Cancer Driver | No | 69 | 0.143 | 66 | 11 | 0.167 | 0 |
| RASGRF1 | RASGRF1 | Q13972 | Ras-specific guanine nucleotide-releasing factor 1 | chr15 | GO:0046579 | Not Cancer Driver | No | 226 | 0.178 | 332 | 64 | 0.193 | 0 |
| RASGRP1 | RASGRP1 | O95267 | RAS guanyl-releasing protein 1 | chr15 | GO:0046579 | Not Cancer Driver | No | 96 | 0.12 | 191 | 12 | 0.063 | 1 |
| RASGRP4_ENST00000587738 | RASGRP4 | Q8TDF6 | RAS guanyl-releasing protein 4 | chr19 | GO:0046579 | Not Cancer Driver | No | 96 | 0.143 | 184 | 40 | 0.217 | 0 |
| ROBO1 | ROBO1 | Q9Y6N7 | Roundabout homolog 1 | chr3 | GO:0046579 | Not Cancer Driver | No | 353 | 0.214 | 1122 | 234 | 0.209 | 0 |
| RTN4R | RTN4R | Q9BZR6 | Reticulon-4 receptor | chr22 | GO:0046579 | Not Cancer Driver | No | 38 | 0.08 | 148 | 17 | 0.115 | 5 |
| SHOC2 | SHOC2 | Q9UQ13 | Leucine-rich repeat protein SHOC-2 | chr10 | GO:0046579 | Not Cancer Driver | No | 55 | 0.095 | 110 | 12 | 0.109 | 2 |
| STK19 | STK19 | P49842 | Serine/threonine-protein kinase 19 | chr6 | GO:0046579 | Not Cancer Driver | No | 60 | 0.163 | 129 | 28 | 0.217 | 0 |
| SYNPO2L | SYNPO2L | Q9H987 | Synaptopodin 2-like protein | chr10 | GO:0046579 | Not Cancer Driver | No | 103 | 0.105 | 950 | 99 | 0.104 | 0 |