Total number of protein in "GO:0046488" GO term: 67
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ATG14 | ATG14 | Q6ZNE5 | Beclin 1-associated autophagy-related key regulator | chr14 | GO:0046488 | Not Cancer Driver | No | 48 | 0.098 | 209 | 24 | 0.115 | 0 |
| ATM_ENST00000452508 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:0046488 | Census, Compendium | Yes | 469 | 0.153 | 225 | 39 | 0.173 | 41 |
| BECN1_ENST00000590099 | BECN1 | Q14457 | Beclin-1 | chr17 | GO:0046488 | Not Cancer Driver | No | 45 | 0.1 | 190 | 19 | 0.1 | 0 |
| CSF1R | CSF1R | P07333 | Macrophage colony-stimulating factor 1 receptor | chr5 | GO:0046488 | Census | Yes | 133 | 0.137 | 124 | 17 | 0.137 | 20 |
| FIG4 | FIG4 | Q92562 | Polyphosphoinositide phosphatase | chr6 | GO:0046488 | Not Cancer Driver | No | 114 | 0.126 | 177 | 26 | 0.147 | 7 |
| GALR2 | GALR2 | O43603 | Galanin receptor type 2 | chr17 | GO:0046488 | Not Cancer Driver | No | 40 | 0.103 | 0 | 0 | 0.0 | 0 |
| GPLD1 | GPLD1 | P80108 | Phosphatidylinositol-glycan-specific phospholipase D | chr6 | GO:0046488 | Not Cancer Driver | No | 153 | 0.182 | 36 | 9 | 0.25 | 0 |
| INPP4A | INPP4A | Q96PE3 | Inositol polyphosphate-4-phosphatase type I A | chr2 | GO:0046488 | Not Cancer Driver | No | 114 | 0.117 | 153 | 20 | 0.131 | 0 |
| INPP4B_ENST00000513000 | INPP4B | O15327 | Inositol polyphosphate 4-phosphatase type II | chr4 | GO:0046488 | Not Cancer Driver | No | 145 | 0.157 | 191 | 36 | 0.188 | 0 |
| INPP5A | INPP5A | Q14642 | Inositol polyphosphate-5-phosphatase A | chr10 | GO:0046488 | Not Cancer Driver | No | 59 | 0.143 | 7 | 4 | 0.571 | 0 |
| INPP5B_ENST00000373026 | INPP5B | P32019 | Type II inositol 1,4,5-trisphosphate 5-phosphatase | chr1 | GO:0046488 | Not Cancer Driver | No | 108 | 0.109 | 114 | 11 | 0.096 | 0 |
| INPP5D | INPP5D | Q92835 | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 | chr2 | GO:0046488 | Not Cancer Driver | No | 176 | 0.148 | 578 | 90 | 0.156 | 0 |
| INPP5E | INPP5E | Q9NRR6 | Phosphatidylinositol polyphosphate 5-phosphatase type IV | chr9 | GO:0046488 | Not Cancer Driver | No | 43 | 0.067 | 272 | 16 | 0.059 | 15 |
| INPP5F | INPP5F | Q9Y2H2 | Phosphatidylinositide phosphatase SAC2 | chr10 | GO:0046488 | Not Cancer Driver | No | 138 | 0.122 | 394 | 45 | 0.114 | 0 |
| INPP5J | INPP5J | Q15735 | Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A | chr22 | GO:0046488 | Not Cancer Driver | No | 102 | 0.101 | 629 | 42 | 0.067 | 0 |
| INPP5K | INPP5K | Q9BT40 | Inositol polyphosphate 5-phosphatase K | chr17 | GO:0046488 | Not Cancer Driver | No | 42 | 0.094 | 34 | 2 | 0.059 | 7 |
| INPPL1 | INPPL1 | O15357 | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 | chr11 | GO:0046488 | Not Cancer Driver | No | 174 | 0.138 | 566 | 76 | 0.134 | 4 |
| IP6K3 | IP6K3 | Q96PC2 | Inositol hexakisphosphate kinase 3 | chr6 | GO:0046488 | Not Cancer Driver | No | 85 | 0.207 | 149 | 34 | 0.228 | 0 |
| LCLAT1 | LCLAT1 | Q6UWP7 | Lysocardiolipin acyltransferase 1 | chr2 | GO:0046488 | Not Cancer Driver | No | 59 | 0.143 | 9 | 3 | 0.333 | 0 |
| LPGAT1 | LPGAT1 | Q92604 | Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 | chr1 | GO:0046488 | Not Cancer Driver | No | 38 | 0.103 | 11 | 0 | 0.0 | 0 |
| MBOAT7 | MBOAT7 | Q96N66 | Lysophospholipid acyltransferase 7 | chr19 | GO:0046488 | Not Cancer Driver | No | 69 | 0.146 | 25 | 3 | 0.12 | 0 |
| MTM1 | MTM1 | Q13496 | Myotubularin | chrX | GO:0046488 | Not Cancer Driver | No | 112 | 0.186 | 79 | 9 | 0.114 | 57 |
| MTMR10 | MTMR10 | Q9NXD2 | Myotubularin-related protein 10 | chr15 | GO:0046488 | Not Cancer Driver | No | 79 | 0.102 | 98 | 7 | 0.071 | 0 |
| MTMR11 | MTMR11 | A4FU01 | Myotubularin-related protein 11 | chr1 | GO:0046488 | Not Cancer Driver | No | 108 | 0.152 | 147 | 17 | 0.116 | 0 |
| MTMR12 | MTMR12 | Q9C0I1 | Myotubularin-related protein 12 | chr5 | GO:0046488 | Not Cancer Driver | No | 105 | 0.141 | 130 | 16 | 0.123 | 0 |
| MTMR1_ENST00000370390 | MTMR1 | Q13613 | Myotubularin-related protein 1 | chrX | GO:0046488 | Not Cancer Driver | No | 114 | 0.171 | 146 | 21 | 0.144 | 0 |
| MTMR2 | MTMR2 | Q13614 | Myotubularin-related protein 2 | chr11 | GO:0046488 | Not Cancer Driver | No | 70 | 0.109 | 140 | 16 | 0.114 | 1 |
| MTMR3 | MTMR3 | Q13615 | Myotubularin-related protein 3 | chr22 | GO:0046488 | Not Cancer Driver | No | 130 | 0.109 | 501 | 66 | 0.132 | 0 |
| MTMR4 | MTMR4 | Q9NYA4 | Myotubularin-related protein 4 | chr17 | GO:0046488 | Not Cancer Driver | No | 147 | 0.123 | 474 | 59 | 0.124 | 0 |
| MTMR6 | MTMR6 | Q9Y217 | Myotubularin-related protein 6 | chr13 | GO:0046488 | Not Cancer Driver | No | 87 | 0.14 | 68 | 16 | 0.235 | 0 |
| MTMR7 | MTMR7 | Q9Y216 | Myotubularin-related protein 7 | chr8 | GO:0046488 | Not Cancer Driver | No | 98 | 0.148 | 160 | 26 | 0.163 | 0 |
| MTMR8 | MTMR8 | Q96EF0 | Myotubularin-related protein 8 | chrX | GO:0046488 | Not Cancer Driver | No | 140 | 0.199 | 55 | 8 | 0.145 | 0 |
| MTMR9 | MTMR9 | Q96QG7 | Myotubularin-related protein 9 | chr8 | GO:0046488 | Not Cancer Driver | No | 60 | 0.109 | 45 | 7 | 0.156 | 0 |
| OCRL | OCRL | Q01968 | Inositol polyphosphate 5-phosphatase OCRL | chrX | GO:0046488 | Not Cancer Driver | No | 151 | 0.168 | 126 | 24 | 0.19 | 41 |
| PDGFRB | PDGFRB | P09619 | Platelet-derived growth factor receptor beta | chr5 | GO:0046488 | Census, Compendium | Yes | 164 | 0.148 | 231 | 44 | 0.19 | 7 |
| PIK3C2A | PIK3C2A | O00443 | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha | chr11 | GO:0046488 | Not Cancer Driver | No | 187 | 0.111 | 350 | 43 | 0.123 | 0 |
| PIK3C2B | PIK3C2B | O00750 | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta | chr1 | GO:0046488 | Not Cancer Driver | No | 241 | 0.147 | 425 | 71 | 0.167 | 0 |
| PIK3C2G_ENST00000433979 | PIK3C2G | O75747 | Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma | chr12 | GO:0046488 | Not Cancer Driver | No | 283 | 0.196 | 211 | 37 | 0.175 | 0 |
| PIK3C3 | PIK3C3 | Q8NEB9 | Phosphatidylinositol 3-kinase catalytic subunit type 3 | chr18 | GO:0046488 | Not Cancer Driver | No | 127 | 0.143 | 191 | 34 | 0.178 | 0 |
| PIK3CA | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | GO:0046488 | Census, Compendium | Yes | 1669 | 1.563 | 38 | 11 | 0.289 | 30 |
| PIK3CB_ENST00000477593 | PIK3CB | P42338 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | chr3 | GO:0046488 | Census, Compendium | Yes | 150 | 0.14 | 42 | 4 | 0.095 | 0 |
| PIK3CD | PIK3CD | O00329 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | chr1 | GO:0046488 | Not Cancer Driver | No | 140 | 0.134 | 60 | 13 | 0.217 | 1 |
| PIK3CG | PIK3CG | P48736 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | chr7 | GO:0046488 | Not Cancer Driver | No | 318 | 0.289 | 121 | 39 | 0.322 | 0 |
| PIK3R3_ENST00000372006 | PIK3R3 | Q92569 | Phosphatidylinositol 3-kinase regulatory subunit gamma | chr1 | GO:0046488 | Not Cancer Driver | No | 51 | 0.111 | 149 | 20 | 0.134 | 0 |
| PIK3R4 | PIK3R4 | Q99570 | Phosphoinositide 3-kinase regulatory subunit 4 | chr3 | GO:0046488 | Not Cancer Driver | No | 193 | 0.142 | 315 | 45 | 0.143 | 0 |
| PIKFYVE | PIKFYVE | Q9Y2I7 | 1-phosphatidylinositol 3-phosphate 5-kinase | chr2 | GO:0046488 | Not Cancer Driver | No | 278 | 0.133 | 848 | 101 | 0.119 | 1 |
| PIP4K2A | PIP4K2A | P48426 | Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha | chr10 | GO:0046488 | Not Cancer Driver | No | 56 | 0.138 | 123 | 15 | 0.122 | 0 |
| PIP4K2C_ENST00000540759 | PIP4K2C | Q8TBX8 | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma | chr12 | GO:0046488 | Not Cancer Driver | No | 62 | 0.147 | 111 | 23 | 0.207 | 0 |
| PIP4P1_ENST00000250489 | PIP4P1 | Q86T03 | Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase | chr14 | GO:0046488 | Not Cancer Driver | No | 36 | 0.13 | 78 | 4 | 0.051 | 0 |
| PIP4P2 | PIP4P2 | Q8N4L2 | Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase | chr8 | GO:0046488 | Not Cancer Driver | No | 41 | 0.16 | 46 | 4 | 0.087 | 0 |
| PLA2G3 | PLA2G3 | Q9NZ20 | Group 3 secretory phospholipase A2 | chr22 | GO:0046488 | Not Cancer Driver | No | 115 | 0.226 | 175 | 39 | 0.223 | 0 |
| PLA2G4D | PLA2G4D | Q86XP0 | Cytosolic phospholipase A2 delta | chr15 | GO:0046488 | Not Cancer Driver | No | 115 | 0.141 | 172 | 17 | 0.099 | 0 |
| PLA2G4E | PLA2G4E | Q3MJ16 | Cytosolic phospholipase A2 epsilon | chr15 | GO:0046488 | Not Cancer Driver | No | 71 | 0.082 | 123 | 6 | 0.049 | 0 |
| PLCB1 | PLCB1 | Q9NQ66 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 | chr20 | GO:0046488 | Not Cancer Driver | No | 313 | 0.257 | 481 | 104 | 0.216 | 0 |
| PLCB2 | PLCB2 | Q00722 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 | chr15 | GO:0046488 | Not Cancer Driver | No | 161 | 0.136 | 495 | 51 | 0.103 | 0 |
| PLCB3 | PLCB3 | Q01970 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 | chr11 | GO:0046488 | Not Cancer Driver | No | 144 | 0.117 | 595 | 68 | 0.114 | 1 |
| PLCD1_ENST00000334661 | PLCD1 | P51178 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 | chr3 | GO:0046488 | Not Cancer Driver | No | 94 | 0.124 | 111 | 13 | 0.117 | 2 |
| PLCD4_ENST00000417849 | PLCD4 | Q9BRC7 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 | chr2 | GO:0046488 | Not Cancer Driver | No | 78 | 0.102 | 90 | 5 | 0.056 | 0 |
| PLCG1_ENST00000373271 | PLCG1 | P19174 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | chr20 | GO:0046488 | Census, Compendium | Yes | 158 | 0.122 | 186 | 21 | 0.113 | 0 |
| PLCH2 | PLCH2 | O75038 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 | chr1 | GO:0046488 | Not Cancer Driver | No | 145 | 0.102 | 786 | 71 | 0.09 | 0 |
| PLEK | PLEK | P08567 | Pleckstrin | chr2 | GO:0046488 | Not Cancer Driver | No | 81 | 0.231 | 39 | 9 | 0.231 | 0 |
| PTEN | PTEN | P60484 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | chr10 | GO:0046488 | Census, Compendium | Yes | 505 | 1.253 | 76 | 4 | 0.053 | 41 |
| SACM1L | SACM1L | Q9NTJ5 | Phosphatidylinositol-3-phosphatase SAC1 | chr3 | GO:0046488 | Not Cancer Driver | No | 41 | 0.07 | 0 | 0 | 0.0 | 0 |
| SYNJ1 | SYNJ1 | O43426 | Synaptojanin-1 | chr21 | GO:0046488 | Not Cancer Driver | No | 208 | 0.132 | 584 | 76 | 0.13 | 3 |
| SYNJ2 | SYNJ2 | O15056 | Synaptojanin-2 | chr6 | GO:0046488 | Not Cancer Driver | No | 189 | 0.126 | 545 | 70 | 0.128 | 0 |
| TPTE2 | TPTE2 | Q6XPS3 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 | chr13 | GO:0046488 | Not Cancer Driver | No | 210 | 0.402 | 33 | 13 | 0.394 | 0 |
| UVRAG | UVRAG | Q9P2Y5 | UV radiation resistance-associated gene protein | chr11 | GO:0046488 | Not Cancer Driver | No | 89 | 0.127 | 243 | 28 | 0.115 | 0 |