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Total number of protein in "GO:0046434" GO term:  128

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCD1 ABCD1 P33897 ATP-binding cassette sub-family D member 1 chrX GO:0046434 Not Cancer Driver No 106 0.142 75 5 0.067 138
ABHD12B ABHD12B Q7Z5M8 Protein ABHD12B chr14 GO:0046434 Not Cancer Driver No 34 0.094 16 1 0.062 0
ABHD12_ENST00000339157 ABHD12 Q8N2K0 Lysophosphatidylserine lipase ABHD12 chr20 GO:0046434 Not Cancer Driver No 45 0.113 8 1 0.125 1
ABHD16A ABHD16A O95870 Phosphatidylserine lipase ABHD16A chr6 GO:0046434 Not Cancer Driver No 69 0.124 53 15 0.283 0
ABHD16B ABHD16B Q9H3Z7 Protein ABHD16B chr20 GO:0046434 Not Cancer Driver No 41 0.087 31 2 0.065 0
ACAT1 ACAT1 P24752 Acetyl-CoA acetyltransferase, mitochondrial chr11 GO:0046434 Not Cancer Driver No 45 0.105 32 1 0.031 10
ACOT7 ACOT7 O00154 Cytosolic acyl coenzyme A thioester hydrolase chr1 GO:0046434 Not Cancer Driver No 43 0.113 77 16 0.208 0
ADA ADA P00813 Adenosine deaminase chr20 GO:0046434 Not Cancer Driver No 50 0.138 44 9 0.205 27
AMPD3_ENST00000529507 AMPD3 Q01432 AMP deaminase 3 chr11 GO:0046434 Not Cancer Driver No 132 0.172 207 38 0.184 10
BPNT1_ENST00000322067 BPNT1 O95861 3'(2'),5'-bisphosphate nucleotidase 1 chr1 GO:0046434 Not Cancer Driver No 44 0.143 9 0 0.0 0
CNP CNP P09543 2',3'-cyclic-nucleotide 3'-phosphodiesterase chr17 GO:0046434 Not Cancer Driver No 36 0.086 71 2 0.028 0
DCTPP1 DCTPP1 Q9H773 dCTP pyrophosphatase 1 chr16 GO:0046434 Not Cancer Driver No 14 0.082 88 9 0.102 0
DERA DERA Q9Y315 Deoxyribose-phosphate aldolase chr12 GO:0046434 Not Cancer Driver No 33 0.104 2 0 0.0 0
DNPH1 DNPH1 O43598 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 chr6 GO:0046434 Not Cancer Driver No 15 0.086 49 3 0.061 0
DPYD DPYD Q12882 Dihydropyrimidine dehydrogenase [NADP(+)] chr1 GO:0046434 Not Cancer Driver No 303 0.296 77 23 0.299 3
DPYS DPYS Q14117 Dihydropyrimidinase chr8 GO:0046434 Not Cancer Driver No 148 0.285 103 28 0.272 5
DUT DUT P33316 Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial chr15 GO:0046434 Not Cancer Driver No 19 0.075 128 8 0.062 0
ENPP2_ENST00000075322 ENPP2 Q13822 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 chr8 GO:0046434 Not Cancer Driver No 168 0.195 81 16 0.198 0
ENPP7 ENPP7 Q6UWV6 Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 chr17 GO:0046434 Not Cancer Driver No 102 0.223 65 19 0.292 0
ENTPD1_ENST00000371205 ENTPD1 P49961 Ectonucleoside triphosphate diphosphohydrolase 1 chr10 GO:0046434 Not Cancer Driver No 63 0.124 16 2 0.125 1
ENTPD2 ENTPD2 Q9Y5L3 Ectonucleoside triphosphate diphosphohydrolase 2 chr9 GO:0046434 Not Cancer Driver No 36 0.073 32 0 0.0 0
ENTPD3 ENTPD3 O75355 Ectonucleoside triphosphate diphosphohydrolase 3 chr3 GO:0046434 Not Cancer Driver No 64 0.121 14 2 0.143 0
ENTPD4 ENTPD4 Q9Y227 Ectonucleoside triphosphate diphosphohydrolase 4 chr8 GO:0046434 Not Cancer Driver No 67 0.109 26 2 0.077 0
ENTPD5 ENTPD5 O75356 Nucleoside diphosphate phosphatase ENTPD5 chr14 GO:0046434 Not Cancer Driver No 41 0.096 6 1 0.167 0
ENTPD6 ENTPD6 O75354 Ectonucleoside triphosphate diphosphohydrolase 6 chr20 GO:0046434 Not Cancer Driver No 68 0.14 41 6 0.146 0
ENTPD7 ENTPD7 Q9NQZ7 Ectonucleoside triphosphate diphosphohydrolase 7 chr10 GO:0046434 Not Cancer Driver No 90 0.149 26 3 0.115 0
ENTPD8 ENTPD8 Q5MY95 Ectonucleoside triphosphate diphosphohydrolase 8 chr9 GO:0046434 Not Cancer Driver No 46 0.093 5 0 0.0 0
FHIT_ENST00000492590 FHIT P49789 Bis(5'-adenosyl)-triphosphatase chr3 GO:0046434 Census, Compendium Yes 35 0.238 45 9 0.2 0
FITM2 FITM2 Q8N6M3 Acyl-coenzyme A diphosphatase FITM2 chr20 GO:0046434 Not Cancer Driver No 28 0.107 0 0 0.0 1
GDA_ENST00000358399 GDA Q9Y2T3 Guanine deaminase chr9 GO:0046434 Not Cancer Driver No 86 0.189 22 7 0.318 0
GDPD3 GDPD3 Q7L5L3 Lysophospholipase D GDPD3 chr16 GO:0046434 Not Cancer Driver No 50 0.157 12 2 0.167 0
GPD1 GPD1 P21695 Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic chr12 GO:0046434 Not Cancer Driver No 59 0.169 2 0 0.0 1
GPD1L GPD1L Q8N335 Glycerol-3-phosphate dehydrogenase 1-like protein chr3 GO:0046434 Not Cancer Driver No 40 0.114 13 1 0.077 0
HPRT1 HPRT1 P00492 Hypoxanthine-guanine phosphoribosyltransferase chrX GO:0046434 Not Cancer Driver No 22 0.101 3 0 0.0 62
IMPA1_ENST00000256108 IMPA1 P29218 Inositol monophosphatase 1 chr8 GO:0046434 Not Cancer Driver No 36 0.13 3 0 0.0 0
IMPA2 IMPA2 O14732 Inositol monophosphatase 2 chr18 GO:0046434 Not Cancer Driver No 44 0.153 21 1 0.048 0
IMPAD1 BPNT2 Q9NX62 Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase chr8 GO:0046434 Not Cancer Driver No 45 0.125 86 10 0.116 2
INPP1 INPP1 P49441 Inositol polyphosphate 1-phosphatase chr2 GO:0046434 Not Cancer Driver No 44 0.11 23 1 0.043 0
INPP4B_ENST00000513000 INPP4B O15327 Inositol polyphosphate 4-phosphatase type II chr4 GO:0046434 Not Cancer Driver No 145 0.157 191 36 0.188 0
INPP5A INPP5A Q14642 Inositol polyphosphate-5-phosphatase A chr10 GO:0046434 Not Cancer Driver No 59 0.143 7 4 0.571 0
INPP5B_ENST00000373026 INPP5B P32019 Type II inositol 1,4,5-trisphosphate 5-phosphatase chr1 GO:0046434 Not Cancer Driver No 108 0.109 114 11 0.096 0
INPP5E INPP5E Q9NRR6 Phosphatidylinositol polyphosphate 5-phosphatase type IV chr9 GO:0046434 Not Cancer Driver No 43 0.067 272 16 0.059 15
INPP5F INPP5F Q9Y2H2 Phosphatidylinositide phosphatase SAC2 chr10 GO:0046434 Not Cancer Driver No 138 0.122 394 45 0.114 0
INPP5J INPP5J Q15735 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A chr22 GO:0046434 Not Cancer Driver No 102 0.101 629 42 0.067 0
INPP5K INPP5K Q9BT40 Inositol polyphosphate 5-phosphatase K chr17 GO:0046434 Not Cancer Driver No 42 0.094 34 2 0.059 7
ITPA ITPA Q9BY32 Inosine triphosphate pyrophosphatase chr20 GO:0046434 Not Cancer Driver No 21 0.108 10 1 0.1 1
LIPC_ENST00000356113 LIPC P11150 Hepatic triacylglycerol lipase chr15 GO:0046434 Not Cancer Driver No 91 0.182 17 3 0.176 2
MBD4 MBD4 O95243 Methyl-CpG-binding domain protein 4 chr3 GO:0046434 Not Cancer Driver No 61 0.105 268 27 0.101 0
MLYCD MLYCD O95822 Malonyl-CoA decarboxylase, mitochondrial chr16 GO:0046434 Not Cancer Driver No 41 0.083 82 0 0.0 0
MTMR2 MTMR2 Q13614 Myotubularin-related protein 2 chr11 GO:0046434 Not Cancer Driver No 70 0.109 140 16 0.114 1
MTMR7 MTMR7 Q9Y216 Myotubularin-related protein 7 chr8 GO:0046434 Not Cancer Driver No 98 0.148 160 26 0.163 0
NEIL1_ENST00000564784 NEIL1 Q96FI4 Endonuclease 8-like 1 chr15 GO:0046434 Not Cancer Driver No 41 0.105 165 14 0.085 0
NEIL2 NEIL2 Q969S2 Endonuclease 8-like 2 chr8 GO:0046434 Not Cancer Driver No 31 0.093 145 14 0.097 0
NT5C NT5C Q8TCD5 5'(3')-deoxyribonucleotidase, cytosolic type chr17 GO:0046434 Not Cancer Driver No 19 0.095 4 0 0.0 0
NT5C1A NT5C1A Q9BXI3 Cytosolic 5'-nucleotidase 1A chr1 GO:0046434 Not Cancer Driver No 86 0.234 95 16 0.168 0
NT5C1B NT5C1B Q96P26 Cytosolic 5'-nucleotidase 1B chr2 GO:0046434 Not Cancer Driver No 136 0.223 253 58 0.229 0
NT5C2_ENST00000404739 NT5C2 P49902 Cytosolic purine 5'-nucleotidase chr10 GO:0046434 Census Yes 57 0.102 85 8 0.094 0
NT5E NT5E P21589 5'-nucleotidase chr6 GO:0046434 Not Cancer Driver No 61 0.106 26 2 0.077 1
NT5M NT5M Q9NPB1 5'(3')-deoxyribonucleotidase, mitochondrial chr17 GO:0046434 Not Cancer Driver No 20 0.088 0 0 0.0 0
NTHL1 NTHL1 P78549 Endonuclease III-like protein 1 chr16 GO:0046434 Census Yes 38 0.122 147 18 0.122 0
NTSR1 NTSR1 P30989 Neurotensin receptor type 1 chr20 GO:0046434 Not Cancer Driver No 85 0.203 23 1 0.043 0
NUDT10_ENST00000356450 NUDT10 Q8NFP7 Diphosphoinositol polyphosphate phosphohydrolase 3-alpha chrX GO:0046434 Not Cancer Driver No 29 0.177 68 8 0.118 0
NUDT11 NUDT11 Q96G61 Diphosphoinositol polyphosphate phosphohydrolase 3-beta chrX GO:0046434 Not Cancer Driver No 30 0.183 65 13 0.2 0
NUDT12 NUDT12 Q9BQG2 NAD-capped RNA hydrolase NUDT12 chr5 GO:0046434 Not Cancer Driver No 65 0.141 11 2 0.182 0
NUDT13 NUDT13 Q86X67 NAD(P)H pyrophosphatase NUDT13, mitochondrial chr10 GO:0046434 Not Cancer Driver No 40 0.114 19 0 0.0 0
NUDT15 NUDT15 Q9NV35 Nucleotide triphosphate diphosphatase NUDT15 chr13 GO:0046434 Not Cancer Driver No 24 0.146 37 3 0.081 0
NUDT16_ENST00000521288 NUDT16 Q96DE0 U8 snoRNA-decapping enzyme chr3 GO:0046434 Not Cancer Driver No 29 0.149 8 1 0.125 0
NUDT17 NUDT17 P0C025 Nucleoside diphosphate-linked moiety X motif 17 chr1 GO:0046434 Not Cancer Driver No 33 0.101 91 15 0.165 0
NUDT18 NUDT18 Q6ZVK8 8-oxo-dGDP phosphatase NUDT18 chr8 GO:0046434 Not Cancer Driver No 22 0.068 39 3 0.077 0
NUDT19 NUDT19 A8MXV4 Acyl-coenzyme A diphosphatase NUDT19 chr19 GO:0046434 Not Cancer Driver No 27 0.072 131 5 0.038 0
NUDT3 NUDT3 O95989 Diphosphoinositol polyphosphate phosphohydrolase 1 chr6 GO:0046434 Not Cancer Driver No 22 0.128 38 5 0.132 0
NUDT4B NUDT4B A0A024RBG1 Diphosphoinositol polyphosphate phosphohydrolase NUDT4B chr1 GO:0046434 Not Cancer Driver No 2 0.011 53 0 0.0 0
NUDT4_ENST00000415493 NUDT4 Q9NZJ9 Diphosphoinositol polyphosphate phosphohydrolase 2 chr12 GO:0046434 Not Cancer Driver No 20 0.111 53 9 0.17 0
NUDT5_ENST00000537776 NUDT5 Q9UKK9 ADP-sugar pyrophosphatase chr10 GO:0046434 Not Cancer Driver No 27 0.123 90 11 0.122 0
NUDT7 NUDT7 P0C024 Peroxisomal coenzyme A diphosphatase NUDT7 chr16 GO:0046434 Not Cancer Driver No 45 0.189 42 4 0.095 0
NUDT8 NUDT8 Q8WV74 Mitochondrial coenzyme A diphosphatase NUDT8 chr11 GO:0046434 Not Cancer Driver No 22 0.093 69 10 0.145 0
NUDT9 NUDT9 Q9BW91 ADP-ribose pyrophosphatase, mitochondrial chr4 GO:0046434 Not Cancer Driver No 27 0.077 177 16 0.09 0
OCRL OCRL Q01968 Inositol polyphosphate 5-phosphatase OCRL chrX GO:0046434 Not Cancer Driver No 151 0.168 126 24 0.19 41
OGG1_ENST00000344629 OGG1 O15527 N-glycosylase/DNA lyase chr3 GO:0046434 Not Cancer Driver No 37 0.107 71 12 0.169 0
PDE10A_ENST00000366882 PDE10A Q9Y233 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A chr6 GO:0046434 Not Cancer Driver No 198 0.254 79 21 0.266 4
PDE2A PDE2A O00408 cGMP-dependent 3',5'-cyclic phosphodiesterase chr11 GO:0046434 Not Cancer Driver No 137 0.146 99 7 0.071 0
PDE4A PDE4A P27815 cAMP-specific 3',5'-cyclic phosphodiesterase 4A chr19 GO:0046434 Not Cancer Driver No 123 0.139 559 67 0.12 0
PDE4B PDE4B Q07343 cAMP-specific 3',5'-cyclic phosphodiesterase 4B chr1 GO:0046434 Not Cancer Driver No 119 0.162 363 42 0.116 0
PDE4C PDE4C Q08493 cAMP-specific 3',5'-cyclic phosphodiesterase 4C chr19 GO:0046434 Not Cancer Driver No 122 0.171 362 61 0.169 0
PDE4D PDE4D Q08499 cAMP-specific 3',5'-cyclic phosphodiesterase 4D chr5 GO:0046434 Not Cancer Driver No 86 0.106 464 54 0.116 12
PDE5A PDE5A O76074 cGMP-specific 3',5'-cyclic phosphodiesterase chr4 GO:0046434 Not Cancer Driver No 113 0.129 163 23 0.141 0
PDE7A PDE7A Q13946 High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A chr8 GO:0046434 Not Cancer Driver No 49 0.102 30 7 0.233 0
PDE7B PDE7B Q9NP56 cAMP-specific 3',5'-cyclic phosphodiesterase 7B chr6 GO:0046434 Not Cancer Driver No 74 0.164 47 7 0.149 0
PDE8A_ENST00000394553 PDE8A O60658 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A chr15 GO:0046434 Not Cancer Driver No 78 0.094 187 17 0.091 0
PDE8B PDE8B O95263 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B chr5 GO:0046434 Not Cancer Driver No 144 0.163 208 19 0.091 1
PDE9A PDE9A O76083 High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A chr21 GO:0046434 Not Cancer Driver No 91 0.153 160 34 0.212 0
PDXP PDXP Q96GD0 Chronophin chr22 GO:0046434 Not Cancer Driver No 14 0.047 38 4 0.105 0
PGM2 PGM2 Q96G03 Phosphopentomutase chr4 GO:0046434 Not Cancer Driver No 79 0.129 108 13 0.12 0
PLA2G10 PLA2G10 O15496 Group 10 secretory phospholipase A2 chr16 GO:0046434 Not Cancer Driver No 5 0.03 0 0 0.0 0
PLA2G15 PLA2G15 Q8NCC3 Phospholipase A2 group XV chr16 GO:0046434 Not Cancer Driver No 61 0.148 11 3 0.273 0
PLA2G4A PLA2G4A P47712 Cytosolic phospholipase A2 chr1 GO:0046434 Not Cancer Driver No 149 0.199 129 28 0.217 1
PLA2G5 PLA2G5 P39877 Phospholipase A2 group V chr1 GO:0046434 Not Cancer Driver No 24 0.174 0 0 0.0 2
PLA2G6 PLA2G6 O60733 85/88 kDa calcium-independent phospholipase A2 chr22 GO:0046434 Not Cancer Driver No 108 0.134 148 23 0.155 11
PLA2G7 PLA2G7 Q13093 Platelet-activating factor acetylhydrolase chr6 GO:0046434 Not Cancer Driver No 70 0.159 27 7 0.259 2
PLB1 PLB1 Q6P1J6 Phospholipase B1, membrane-associated chr2 GO:0046434 Not Cancer Driver No 223 0.153 399 57 0.143 0
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:0046434 Not Cancer Driver No 313 0.257 481 104 0.216 0
PLPP6 PLPP6 Q8IY26 Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6 chr9 GO:0046434 Not Cancer Driver No 16 0.054 80 0 0.0 0
PNLIPRP2 PNLIPRP2 P54317 Pancreatic lipase-related protein 2 chr10 GO:0046434 Not Cancer Driver No 75 0.16 28 2 0.071 0
PNP PNP P00491 Purine nucleoside phosphorylase chr14 GO:0046434 Not Cancer Driver No 38 0.131 29 2 0.069 5
PNPLA7_ENST00000277531 PNPLA7 Q6ZV29 Patatin-like phospholipase domain-containing protein 7 chr9 GO:0046434 Not Cancer Driver No 180 0.137 283 35 0.124 0
PNPLA8 PNPLA8 Q9NP80 Calcium-independent phospholipase A2-gamma chr7 GO:0046434 Not Cancer Driver No 94 0.12 140 18 0.129 0
PON1 PON1 P27169 Serum paraoxonase/arylesterase 1 chr7 GO:0046434 Not Cancer Driver No 80 0.225 10 9 0.9 0
PRTFDC1 PRTFDC1 Q9NRG1 Phosphoribosyltransferase domain-containing protein 1 chr10 GO:0046434 Not Cancer Driver No 29 0.129 3 0 0.0 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0046434 Census, Compendium Yes 505 1.253 76 4 0.053 41
SAMHD1 SAMHD1 Q9Y3Z3 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 chr20 GO:0046434 Not Cancer Driver No 104 0.166 91 14 0.154 13
SARM1 SARM1 Q6SZW1 NAD(+) hydrolase SARM1 chr17 GO:0046434 Not Cancer Driver No 36 0.05 80 4 0.05 0
SMPD1 SMPD1 P17405 Sphingomyelin phosphodiesterase chr11 GO:0046434 Not Cancer Driver No 93 0.147 51 4 0.078 111
SMPD2 SMPD2 O60906 Sphingomyelin phosphodiesterase 2 chr6 GO:0046434 Not Cancer Driver No 45 0.106 48 5 0.104 0
SMPD3 SMPD3 Q9NY59 Sphingomyelin phosphodiesterase 3 chr16 GO:0046434 Not Cancer Driver No 92 0.14 224 29 0.129 0
SMPD4 SMPD4 Q9NXE4 Sphingomyelin phosphodiesterase 4 chr2 GO:0046434 Not Cancer Driver No 114 0.132 80 12 0.15 1
SMPDL3A SMPDL3A Q92484 Acid sphingomyelinase-like phosphodiesterase 3a chr6 GO:0046434 Not Cancer Driver No 56 0.124 36 3 0.083 0
SMPDL3B SMPDL3B Q92485 Acid sphingomyelinase-like phosphodiesterase 3b chr1 GO:0046434 Not Cancer Driver No 61 0.134 22 7 0.318 0
SMUG1 SMUG1 Q53HV7 Single-strand selective monofunctional uracil DNA glycosylase chr12 GO:0046434 Not Cancer Driver No 33 0.122 46 2 0.043 0
SYNJ1 SYNJ1 O43426 Synaptojanin-1 chr21 GO:0046434 Not Cancer Driver No 208 0.132 584 76 0.13 3
SYNJ2 SYNJ2 O15056 Synaptojanin-2 chr6 GO:0046434 Not Cancer Driver No 189 0.126 545 70 0.128 0
TDG TDG Q13569 G/T mismatch-specific thymine DNA glycosylase chr12 GO:0046434 Not Cancer Driver No 75 0.183 185 31 0.168 0
TYMP_ENST00000395680 TYMP P19971 Thymidine phosphorylase chr22 GO:0046434 Not Cancer Driver No 28 0.058 143 7 0.049 5
UNG UNG P13051 Uracil-DNA glycosylase chr12 GO:0046434 Not Cancer Driver No 34 0.109 96 13 0.135 1
UPB1 UPB1 Q9UBR1 Beta-ureidopropionase chr22 GO:0046434 Not Cancer Driver No 66 0.172 22 7 0.318 8
UPP1_ENST00000395564 UPP1 Q16831 Uridine phosphorylase 1 chr7 GO:0046434 Not Cancer Driver No 47 0.152 13 3 0.231 0
UPP2_ENST00000005756 UPP2 O95045 Uridine phosphorylase 2 chr2 GO:0046434 Not Cancer Driver No 55 0.174 5 1 0.2 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:0046434 Not Cancer Driver No 88 0.109 186 16 0.086 16
XDH XDH P47989 Xanthine dehydrogenase/oxidase chr2 GO:0046434 Not Cancer Driver No 279 0.209 134 24 0.179 1