Total number of protein in "GO:0046425" GO term: 32
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ADIPOR1 | ADIPOR1 | Q96A54 | Adiponectin receptor protein 1 | chr1 | GO:0046425 | Not Cancer Driver | No | 63 | 0.168 | 69 | 10 | 0.145 | 0 |
BCL3 | BCL3 | P20749 | B-cell lymphoma 3 protein | chr19 | GO:0046425 | Census | Yes | 44 | 0.097 | 259 | 23 | 0.089 | 0 |
CAV1 | CAV1 | Q03135 | Caveolin-1 | chr7 | GO:0046425 | Not Cancer Driver | No | 30 | 0.169 | 2 | 0 | 0.0 | 0 |
DAB1_ENST00000371231 | DAB1 | O75553 | Disabled homolog 1 | chr1 | GO:0046425 | Not Cancer Driver | No | 200 | 0.34 | 393 | 143 | 0.364 | 0 |
DOT1L | DOT1L | Q8TEK3 | Histone-lysine N-methyltransferase, H3 lysine-79 specific | chr19 | GO:0046425 | Compendium | Yes | 178 | 0.116 | 988 | 118 | 0.119 | 0 |
EGF | EGF | P01133 | Pro-epidermal growth factor | chr4 | GO:0046425 | Not Cancer Driver | No | 184 | 0.152 | 191 | 25 | 0.131 | 1 |
ELP2_ENST00000358232 | ELP2 | Q6IA86 | Elongator complex protein 2 | chr18 | GO:0046425 | Not Cancer Driver | No | 65 | 0.079 | 16 | 2 | 0.125 | 0 |
EPHB2 | EPHB2 | P29323 | Ephrin type-B receptor 2 | chr1 | GO:0046425 | Not Cancer Driver | No | 186 | 0.176 | 119 | 17 | 0.143 | 7 |
GBP7 | GBP7 | Q8N8V2 | Guanylate-binding protein 7 | chr1 | GO:0046425 | Not Cancer Driver | No | 88 | 0.138 | 93 | 8 | 0.086 | 0 |
HES1 | HES1 | Q14469 | Transcription factor HES-1 | chr3 | GO:0046425 | Not Cancer Driver | No | 37 | 0.132 | 226 | 32 | 0.142 | 0 |
HGS | HGS | O14964 | Hepatocyte growth factor-regulated tyrosine kinase substrate | chr17 | GO:0046425 | Not Cancer Driver | No | 109 | 0.14 | 528 | 74 | 0.14 | 0 |
IL9 | IL9 | P15248 | Interleukin-9 | chr5 | GO:0046425 | Not Cancer Driver | No | 12 | 0.083 | 4 | 0 | 0.0 | 0 |
INPP5F | INPP5F | Q9Y2H2 | Phosphatidylinositide phosphatase SAC2 | chr10 | GO:0046425 | Not Cancer Driver | No | 138 | 0.122 | 394 | 45 | 0.114 | 0 |
JAK2 | JAK2 | O60674 | Tyrosine-protein kinase JAK2 | chr9 | GO:0046425 | Census, Compendium | Yes | 136 | 0.12 | 59 | 5 | 0.085 | 5 |
JAK3 | JAK3 | P52333 | Tyrosine-protein kinase JAK3 | chr19 | GO:0046425 | Census, Compendium | Yes | 167 | 0.149 | 63 | 10 | 0.159 | 7 |
LEPROT_ENST00000371065 | LEPROT | O15243 | Leptin receptor gene-related protein | chr1 | GO:0046425 | Not Cancer Driver | No | 16 | 0.122 | 0 | 0 | 0.0 | 0 |
MST1 | MST1 | P26927 | Hepatocyte growth factor-like protein | chr3 | GO:0046425 | Not Cancer Driver | No | 110 | 0.155 | 168 | 19 | 0.113 | 0 |
NEUROD1 | NEUROD1 | Q13562 | Neurogenic differentiation factor 1 | chr2 | GO:0046425 | Not Cancer Driver | No | 84 | 0.236 | 202 | 52 | 0.257 | 2 |
NF2 | NF2 | P35240 | Merlin | chr22 | GO:0046425 | Census, Compendium | Yes | 69 | 0.116 | 252 | 26 | 0.103 | 16 |
PARP14 | PARP14 | Q460N5 | Protein mono-ADP-ribosyltransferase PARP14 | chr3 | GO:0046425 | Not Cancer Driver | No | 221 | 0.123 | 301 | 57 | 0.189 | 0 |
PIBF1 | PIBF1 | Q8WXW3 | Progesterone-induced-blocking factor 1 | chr13 | GO:0046425 | Not Cancer Driver | No | 83 | 0.11 | 419 | 45 | 0.107 | 2 |
PIGU | PIGU | Q9H490 | Phosphatidylinositol glycan anchor biosynthesis class U protein | chr20 | GO:0046425 | Not Cancer Driver | No | 47 | 0.108 | 0 | 0 | 0.0 | 2 |
PPP2CA | PPP2CA | P67775 | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform | chr5 | GO:0046425 | Not Cancer Driver | No | 41 | 0.133 | 12 | 1 | 0.083 | 8 |
PPP2R1A | PPP2R1A | P30153 | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform | chr19 | GO:0046425 | Census, Compendium | Yes | 179 | 0.304 | 0 | 0 | 0.0 | 4 |
PTPN2 | PTPN2 | P17706 | Tyrosine-protein phosphatase non-receptor type 2 | chr18 | GO:0046425 | Not Cancer Driver | No | 57 | 0.137 | 120 | 14 | 0.117 | 0 |
PTPRC | PTPRC | P08575 | Receptor-type tyrosine-protein phosphatase C | chr1 | GO:0046425 | Census, Compendium | Yes | 315 | 0.241 | 462 | 107 | 0.232 | 0 |
PTPRD | PTPRD | P23468 | Receptor-type tyrosine-protein phosphatase delta | chr9 | GO:0046425 | Census, Compendium | Yes | 577 | 0.302 | 747 | 219 | 0.293 | 0 |
SH2B3 | SH2B3 | Q9UQQ2 | SH2B adapter protein 3 | chr12 | GO:0046425 | Census, Compendium | Yes | 48 | 0.083 | 333 | 19 | 0.057 | 0 |
SOCS1 | SOCS1 | O15524 | Suppressor of cytokine signaling 1 | chr16 | GO:0046425 | Census, Compendium | Yes | 22 | 0.104 | 66 | 3 | 0.045 | 2 |
SOCS2_ENST00000536696 | SOCS2 | O14508 | Suppressor of cytokine signaling 2 | chr12 | GO:0046425 | Not Cancer Driver | No | 32 | 0.162 | 61 | 2 | 0.033 | 0 |
SOCS3 | SOCS3 | O14543 | Suppressor of cytokine signaling 3 | chr17 | GO:0046425 | Not Cancer Driver | No | 27 | 0.12 | 111 | 14 | 0.126 | 0 |
VHL | VHL | P40337 | von Hippel-Lindau disease tumor suppressor | chr3 | GO:0046425 | Census, Compendium | Yes | 142 | 0.667 | 117 | 36 | 0.308 | 133 |