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Total number of protein in "GO:0046332" GO term:  78

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACVR1B_ENST00000257963 ACVR1B P36896 Activin receptor type-1B chr12 GO:0046332 Census Yes 114 0.226 0 0 0.0 0
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0046332 Census, Compendium Yes 78 0.153 21 8 0.381 8
ACVRL1 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0046332 Not Cancer Driver No 93 0.185 60 11 0.183 82
ANKRD1 ANKRD1 Q15327 Ankyrin repeat domain-containing protein 1 chr10 GO:0046332 Not Cancer Driver No 52 0.163 83 13 0.157 0
AXIN1 AXIN1 O15169 Axin-1 chr16 GO:0046332 Census, Compendium Yes 120 0.139 619 88 0.142 4
AXIN2 AXIN2 Q9Y2T1 Axin-2 chr17 GO:0046332 Census, Compendium Yes 114 0.135 547 77 0.141 0
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0046332 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0046332 Census, Compendium Yes 66 0.124 21 0 0.0 8
BMPR1B_ENST00000394931 BMPR1B O00238 Bone morphogenetic protein receptor type-1B chr4 GO:0046332 Not Cancer Driver No 84 0.167 64 12 0.188 5
CITED1_ENST00000246139 CITED1 Q99966 Cbp/p300-interacting transactivator 1 chrX GO:0046332 Not Cancer Driver No 24 0.124 166 21 0.127 0
CITED2_ENST00000367651 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:0046332 Not Cancer Driver No 23 0.085 230 18 0.078 0
COL1A2 COL1A2 P08123 Collagen alpha-2(I) chain chr7 GO:0046332 Not Cancer Driver No 372 0.272 1159 329 0.284 83
COL3A1 COL3A1 P02461 Collagen alpha-1(III) chain chr2 GO:0046332 Census Yes 402 0.274 1182 337 0.285 103
COL5A2 COL5A2 P05997 Collagen alpha-2(V) chain chr2 GO:0046332 Not Cancer Driver No 350 0.233 1276 297 0.233 2
CREB3L1 CREB3L1 Q96BA8 Cyclic AMP-responsive element-binding protein 3-like protein 1 chr11 GO:0046332 Census Yes 68 0.131 372 50 0.134 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0046332 Census, Compendium Yes 415 0.531 288 301 1.045 14
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0046332 Not Cancer Driver No 144 0.187 680 125 0.184 0
DDX5 DDX5 P17844 Probable ATP-dependent RNA helicase DDX5 chr17 GO:0046332 Census Yes 74 0.121 225 23 0.102 0
DROSHA_ENST00000344624 DROSHA Q9NRR4 Ribonuclease 3 chr5 GO:0046332 Census, Compendium Yes 175 0.127 682 100 0.147 0
EID2 EID2 Q8N6I1 EP300-interacting inhibitor of differentiation 2 chr19 GO:0046332 Not Cancer Driver No 18 0.076 136 8 0.059 0
FERMT2_ENST00000395631 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 GO:0046332 Not Cancer Driver No 71 0.104 101 10 0.099 0
FKBP1A FKBP1A P62942 Peptidyl-prolyl cis-trans isomerase FKBP1A chr20 GO:0046332 Not Cancer Driver No 15 0.139 39 7 0.179 0
FOS FOS P01100 Protein c-Fos chr14 GO:0046332 Not Cancer Driver No 45 0.118 245 33 0.135 0
FOXH1 FOXH1 O75593 Forkhead box protein H1 chr8 GO:0046332 Not Cancer Driver No 47 0.129 215 25 0.116 0
GATA4_ENST00000335135 GATA4 P43694 Transcription factor GATA-4 chr8 GO:0046332 Not Cancer Driver No 48 0.109 301 34 0.113 18
HIPK2 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 GO:0046332 Not Cancer Driver No 154 0.129 686 96 0.14 0
HMGA2_ENST00000403681 HMGA2 P52926 High mobility group protein HMGI-C chr12 GO:0046332 Census Yes 12 0.11 109 12 0.11 0
IPO7 IPO7 O95373 Importin-7 chr11 GO:0046332 Not Cancer Driver No 138 0.133 202 30 0.149 0
JUN JUN P05412 Transcription factor Jun chr1 GO:0046332 Census Yes 35 0.106 281 25 0.089 0
LDLRAD4 LDLRAD4 O15165 Low-density lipoprotein receptor class A domain-containing protein 4 chr18 GO:0046332 Not Cancer Driver No 66 0.216 191 39 0.204 0
MAGI2 MAGI2 Q86UL8 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 chr7 GO:0046332 Not Cancer Driver No 305 0.21 1086 201 0.185 0
MEF2A_ENST00000354410 MEF2A Q02078 Myocyte-specific enhancer factor 2A chr15 GO:0046332 Not Cancer Driver No 62 0.122 454 56 0.123 0
MEN1 MEN1 O00255 Menin chr11 GO:0046332 Census, Compendium Yes 73 0.119 228 15 0.066 90
MYOCD_ENST00000343344 MYOCD Q8IZQ8 Myocardin chr17 GO:0046332 Not Cancer Driver No 284 0.303 853 263 0.308 0
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0046332 Not Cancer Driver No 119 0.117 320 34 0.106 0
PAX6_ENST00000241001 PAX6 P26367 Paired box protein Pax-6 chr11 GO:0046332 Not Cancer Driver No 72 0.171 337 56 0.166 38
PMEPA1 PMEPA1 Q969W9 Protein TMEPAI chr20 GO:0046332 Not Cancer Driver No 45 0.157 196 34 0.173 0
PML PML P29590 Protein PML chr15 GO:0046332 Census, Compendium Yes 112 0.127 312 34 0.109 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0046332 Census Yes 72 0.143 44 4 0.091 3
PPM1A_ENST00000395076 PPM1A P35813 Protein phosphatase 1A chr14 GO:0046332 Not Cancer Driver No 60 0.157 134 24 0.179 0
PURA PURA Q00577 Transcriptional activator protein Pur-alpha chr5 GO:0046332 Not Cancer Driver No 22 0.068 188 10 0.053 6
PURB PURB Q96QR8 Transcriptional activator protein Pur-beta chr7 GO:0046332 Not Cancer Driver No 27 0.087 161 14 0.087 0
RANBP3 RANBP3 Q9H6Z4 Ran-binding protein 3 chr19 GO:0046332 Not Cancer Driver No 71 0.125 468 54 0.115 0
RANBP3L_ENST00000296604 RANBP3L Q86VV4 Ran-binding protein 3-like chr5 GO:0046332 Not Cancer Driver No 71 0.153 185 33 0.178 0
RGCC RGCC Q9H4X1 Regulator of cell cycle RGCC chr13 GO:0046332 Not Cancer Driver No 9 0.066 81 7 0.086 0
RNF111_ENST00000557998 RNF111 Q6ZNA4 E3 ubiquitin-protein ligase Arkadia chr15 GO:0046332 Not Cancer Driver No 111 0.112 855 96 0.112 0
SAV1 SAV1 Q9H4B6 Protein salvador homolog 1 chr14 GO:0046332 Not Cancer Driver No 42 0.11 243 17 0.07 0
SKI SKI P12755 Ski oncogene chr1 GO:0046332 Census Yes 44 0.06 432 26 0.06 14
SKIL_ENST00000259119 SKIL P12757 Ski-like protein chr3 GO:0046332 Not Cancer Driver No 77 0.113 356 32 0.09 0
SKOR1_ENST00000380035 SKOR1 P84550 SKI family transcriptional corepressor 1 chr15 GO:0046332 Not Cancer Driver No 104 0.108 682 47 0.069 0
SKOR2 SKOR2 Q2VWA4 SKI family transcriptional corepressor 2 chr18 GO:0046332 Not Cancer Driver No 20 0.02 640 8 0.013 0
SMAD1 SMAD1 Q15797 Mothers against decapentaplegic homolog 1 chr4 GO:0046332 Not Cancer Driver No 54 0.116 161 22 0.137 0
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 GO:0046332 Census, Compendium Yes 79 0.169 137 12 0.088 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0046332 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0046332 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMAD5_ENST00000509297 SMAD5 Q99717 Mothers against decapentaplegic homolog 5 chr5 GO:0046332 Not Cancer Driver No 44 0.095 172 11 0.064 0
SMAD6 SMAD6 O43541 Mothers against decapentaplegic homolog 6 chr15 GO:0046332 Not Cancer Driver No 38 0.077 248 7 0.028 7
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0046332 Not Cancer Driver No 40 0.094 139 0 0.0 0
SMAD9 SMAD9 O15198 Mothers against decapentaplegic homolog 9 chr13 GO:0046332 Not Cancer Driver No 79 0.169 132 14 0.106 1
SMURF1 SMURF1 Q9HCE7 E3 ubiquitin-protein ligase SMURF1 chr7 GO:0046332 Not Cancer Driver No 89 0.118 256 31 0.121 0
SMURF2 SMURF2 Q9HAU4 E3 ubiquitin-protein ligase SMURF2 chr17 GO:0046332 Not Cancer Driver No 87 0.116 242 28 0.116 0
SNW1_ENST00000261531 SNW1 Q13573 SNW domain-containing protein 1 chr14 GO:0046332 Not Cancer Driver No 62 0.116 488 56 0.115 0
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 GO:0046332 Not Cancer Driver No 35 0.116 112 14 0.125 12
TCF12_ENST00000267811 TCF12 Q99081 Transcription factor 12 chr15 GO:0046332 Census Yes 105 0.154 680 105 0.154 3
TGFB1I1 TGFB1I1 O43294 Transforming growth factor beta-1-induced transcript 1 protein chr16 GO:0046332 Not Cancer Driver No 61 0.132 219 34 0.155 0
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0046332 Not Cancer Driver No 86 0.171 23 3 0.13 15
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0046332 Census, Compendium Yes 106 0.187 60 16 0.267 25
TGFBR3_ENST00000525962 TGFBR3 Q03167 Transforming growth factor beta receptor type 3 chr1 GO:0046332 Not Cancer Driver No 129 0.152 268 41 0.153 0
TGFBRAP1 TGFBRAP1 Q8WUH2 Transforming growth factor-beta receptor-associated protein 1 chr2 GO:0046332 Not Cancer Driver No 127 0.148 37 8 0.216 0
TOB1 TOB1 P50616 Protein Tob1 chr17 GO:0046332 Not Cancer Driver No 35 0.101 214 18 0.084 0
TRIM33 TRIM33 Q9UPN9 E3 ubiquitin-protein ligase TRIM33 chr1 GO:0046332 Census, Compendium Yes 110 0.098 617 51 0.083 0
USP15 USP15 Q9Y4E8 Ubiquitin carboxyl-terminal hydrolase 15 chr12 GO:0046332 Not Cancer Driver No 136 0.139 259 39 0.151 0
USP9X_ENST00000378308 USP9X Q93008 Probable ubiquitin carboxyl-terminal hydrolase FAF-X chrX GO:0046332 Census, Compendium Yes 339 0.133 405 51 0.126 1
USP9Y USP9Y O00507 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y chrY GO:0046332 Not Cancer Driver No 83 0.032 349 6 0.017 0
YY1 YY1 P25490 Transcriptional repressor protein YY1 chr14 GO:0046332 Not Cancer Driver No 37 0.089 336 26 0.077 2
ZBTB7A_ENST00000601588 ZBTB7A O95365 Zinc finger and BTB domain-containing protein 7A chr19 GO:0046332 Not Cancer Driver No 60 0.103 285 30 0.105 0
ZC3H3 ZC3H3 Q8IXZ2 Zinc finger CCCH domain-containing protein 3 chr8 GO:0046332 Not Cancer Driver No 130 0.137 750 99 0.132 0
ZMIZ1 ZMIZ1 Q9ULJ6 Zinc finger MIZ domain-containing protein 1 chr10 GO:0046332 Not Cancer Driver No 148 0.139 762 111 0.146 5