Total number of protein in "GO:0046165" GO term: 60
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABCA2_ENST00000371605 | ABCA2 | Q9BZC7 | ATP-binding cassette sub-family A member 2 | chr9 | GO:0046165 | Not Cancer Driver | No | 240 | 0.099 | 497 | 44 | 0.089 | 0 |
| ACER1 | ACER1 | Q8TDN7 | Alkaline ceramidase 1 | chr19 | GO:0046165 | Not Cancer Driver | No | 54 | 0.205 | 0 | 0 | 0.0 | 0 |
| ACER2 | ACER2 | Q5QJU3 | Alkaline ceramidase 2 | chr9 | GO:0046165 | Not Cancer Driver | No | 27 | 0.098 | 0 | 0 | 0.0 | 0 |
| ACER3 | ACER3 | Q9NUN7 | Alkaline ceramidase 3 | chr11 | GO:0046165 | Not Cancer Driver | No | 28 | 0.105 | 0 | 0 | 0.0 | 1 |
| ASAH1_ENST00000262097 | ASAH1 | Q13510 | Acid ceramidase | chr8 | GO:0046165 | Not Cancer Driver | No | 47 | 0.119 | 10 | 3 | 0.3 | 14 |
| ASAH2 | ASAH2 | Q9NR71 | Neutral ceramidase | chr10 | GO:0046165 | Not Cancer Driver | No | 71 | 0.091 | 140 | 24 | 0.171 | 0 |
| ASAH2B_ENST00000374006 | ASAH2B | P0C7U1 | Putative inactive neutral ceramidase B | chr10 | GO:0046165 | Not Cancer Driver | No | 9 | 0.055 | 14 | 1 | 0.071 | 0 |
| CACNA1H | CACNA1H | O95180 | Voltage-dependent T-type calcium channel subunit alpha-1H | chr16 | GO:0046165 | Not Cancer Driver | No | 323 | 0.137 | 1045 | 141 | 0.135 | 18 |
| CYP11B1 | CYP11B1 | P15538 | Cytochrome P450 11B1, mitochondrial | chr8 | GO:0046165 | Not Cancer Driver | No | 177 | 0.352 | 7 | 1 | 0.143 | 50 |
| CYP11B2 | CYP11B2 | P19099 | Cytochrome P450 11B2, mitochondrial | chr8 | GO:0046165 | Not Cancer Driver | No | 148 | 0.294 | 6 | 0 | 0.0 | 6 |
| CYP27A1 | CYP27A1 | Q02318 | Sterol 26-hydroxylase, mitochondrial | chr2 | GO:0046165 | Not Cancer Driver | No | 69 | 0.13 | 47 | 11 | 0.234 | 7 |
| CYP27B1 | CYP27B1 | O15528 | 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial | chr12 | GO:0046165 | Not Cancer Driver | No | 71 | 0.14 | 79 | 13 | 0.165 | 18 |
| CYP2R1 | CYP2R1 | Q6VVX0 | Vitamin D 25-hydroxylase | chr11 | GO:0046165 | Not Cancer Driver | No | 53 | 0.106 | 5 | 1 | 0.2 | 1 |
| CYP3A4 | CYP3A4 | P08684 | Cytochrome P450 3A4 | chr7 | GO:0046165 | Not Cancer Driver | No | 91 | 0.181 | 22 | 2 | 0.091 | 1 |
| DBH | DBH | P09172 | Dopamine beta-hydroxylase | chr9 | GO:0046165 | Not Cancer Driver | No | 125 | 0.203 | 71 | 17 | 0.239 | 3 |
| DHCR24 | DHCR24 | Q15392 | Delta(24)-sterol reductase | chr1 | GO:0046165 | Not Cancer Driver | No | 55 | 0.107 | 0 | 0 | 0.0 | 6 |
| DHCR7 | DHCR7 | Q9UBM7 | 7-dehydrocholesterol reductase | chr11 | GO:0046165 | Not Cancer Driver | No | 85 | 0.179 | 7 | 1 | 0.143 | 53 |
| DHDDS_ENST00000236342 | DHDDS | Q86SQ9 | Dehydrodolichyl diphosphate synthase complex subunit DHDDS | chr1 | GO:0046165 | Not Cancer Driver | No | 38 | 0.114 | 19 | 1 | 0.053 | 1 |
| DHFR | DHFR | P00374 | Dihydrofolate reductase | chr5 | GO:0046165 | Not Cancer Driver | No | 16 | 0.086 | 12 | 2 | 0.167 | 2 |
| EBP | EBP | Q15125 | 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase | chrX | GO:0046165 | Not Cancer Driver | No | 30 | 0.13 | 9 | 0 | 0.0 | 9 |
| FGF2_ENST00000614010 | FGF2 | P09038 | Fibroblast growth factor 2 | chr4 | GO:0046165 | Not Cancer Driver | No | 18 | 0.062 | 183 | 5 | 0.027 | 0 |
| GBA_ENST00000368373 | GBA | P04062 | Lysosomal acid glucosylceramidase | chr1 | GO:0046165 | Not Cancer Driver | No | 74 | 0.138 | 38 | 5 | 0.132 | 171 |
| GCH1_ENST00000622544 | GCH1 | P30793 | GTP cyclohydrolase 1 | chr14 | GO:0046165 | Not Cancer Driver | No | 20 | 0.08 | 99 | 5 | 0.051 | 38 |
| GOT1 | GOT1 | P17174 | Aspartate aminotransferase, cytoplasmic | chr10 | GO:0046165 | Not Cancer Driver | No | 56 | 0.136 | 35 | 5 | 0.143 | 0 |
| IMPA1_ENST00000256108 | IMPA1 | P29218 | Inositol monophosphatase 1 | chr8 | GO:0046165 | Not Cancer Driver | No | 36 | 0.13 | 3 | 0 | 0.0 | 0 |
| IMPA2 | IMPA2 | O14732 | Inositol monophosphatase 2 | chr18 | GO:0046165 | Not Cancer Driver | No | 44 | 0.153 | 21 | 1 | 0.048 | 0 |
| IP6K1 | IP6K1 | Q92551 | Inositol hexakisphosphate kinase 1 | chr3 | GO:0046165 | Not Cancer Driver | No | 50 | 0.113 | 216 | 29 | 0.134 | 0 |
| IP6K2 | IP6K2 | Q9UHH9 | Inositol hexakisphosphate kinase 2 | chr3 | GO:0046165 | Not Cancer Driver | No | 45 | 0.106 | 96 | 10 | 0.104 | 0 |
| IP6K3 | IP6K3 | Q96PC2 | Inositol hexakisphosphate kinase 3 | chr6 | GO:0046165 | Not Cancer Driver | No | 85 | 0.207 | 149 | 34 | 0.228 | 0 |
| IPMK | IPMK | Q8NFU5 | Inositol polyphosphate multikinase | chr10 | GO:0046165 | Not Cancer Driver | No | 50 | 0.12 | 108 | 9 | 0.083 | 0 |
| IPPK | IPPK | Q9H8X2 | Inositol-pentakisphosphate 2-kinase | chr9 | GO:0046165 | Not Cancer Driver | No | 55 | 0.112 | 43 | 3 | 0.07 | 0 |
| ISYNA1 | ISYNA1 | Q9NPH2 | Inositol-3-phosphate synthase 1 | chr19 | GO:0046165 | Not Cancer Driver | No | 40 | 0.072 | 83 | 2 | 0.024 | 0 |
| ITPKA | ITPKA | P23677 | Inositol-trisphosphate 3-kinase A | chr15 | GO:0046165 | Not Cancer Driver | No | 28 | 0.061 | 216 | 7 | 0.032 | 0 |
| ITPKB_ENST00000272117 | ITPKB | P27987 | Inositol-trisphosphate 3-kinase B | chr1 | GO:0046165 | Not Cancer Driver | No | 148 | 0.156 | 719 | 119 | 0.166 | 0 |
| ITPKC | ITPKC | Q96DU7 | Inositol-trisphosphate 3-kinase C | chr19 | GO:0046165 | Not Cancer Driver | No | 78 | 0.114 | 452 | 38 | 0.084 | 0 |
| LEP | LEP | P41159 | Leptin | chr7 | GO:0046165 | Not Cancer Driver | No | 29 | 0.174 | 0 | 0 | 0.0 | 2 |
| MOXD1 | MOXD1 | Q6UVY6 | DBH-like monooxygenase protein 1 | chr6 | GO:0046165 | Not Cancer Driver | No | 99 | 0.162 | 29 | 7 | 0.241 | 0 |
| NUS1 | NUS1 | Q96E22 | Dehydrodolichyl diphosphate synthase complex subunit NUS1 | chr6 | GO:0046165 | Not Cancer Driver | No | 21 | 0.072 | 13 | 0 | 0.0 | 1 |
| PARK7_ENST00000377488 | PARK7 | Q99497 | Parkinson disease protein 7 | chr1 | GO:0046165 | Not Cancer Driver | No | 11 | 0.058 | 30 | 0 | 0.0 | 5 |
| PCBD1 | PCBD1 | P61457 | Pterin-4-alpha-carbinolamine dehydratase | chr10 | GO:0046165 | Not Cancer Driver | No | 8 | 0.077 | 7 | 0 | 0.0 | 3 |
| PCBD2_ENST00000254908 | PCBD2 | Q9H0N5 | Pterin-4-alpha-carbinolamine dehydratase 2 | chr5 | GO:0046165 | Not Cancer Driver | No | 6 | 0.046 | 3 | 0 | 0.0 | 0 |
| PCK1 | PCK1 | P35558 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | chr20 | GO:0046165 | Not Cancer Driver | No | 142 | 0.228 | 110 | 28 | 0.255 | 1 |
| PCK2 | PCK2 | Q16822 | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial | chr14 | GO:0046165 | Not Cancer Driver | No | 91 | 0.142 | 139 | 13 | 0.094 | 0 |
| PGP | PGP | A6NDG6 | Glycerol-3-phosphate phosphatase | chr16 | GO:0046165 | Not Cancer Driver | No | 10 | 0.031 | 21 | 0 | 0.0 | 0 |
| PLCG2 | PLCG2 | P16885 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | chr16 | GO:0046165 | Not Cancer Driver | No | 248 | 0.196 | 142 | 30 | 0.211 | 1 |
| PPIP5K1 | PPIP5K1 | Q6PFW1 | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 | chr15 | GO:0046165 | Not Cancer Driver | No | 58 | 0.04 | 544 | 25 | 0.046 | 0 |
| PPIP5K2_ENST00000358359 | PPIP5K2 | O43314 | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 | chr5 | GO:0046165 | Not Cancer Driver | No | 146 | 0.117 | 419 | 54 | 0.129 | 1 |
| PTAFR_ENST00000305392 | PTAFR | P25105 | Platelet-activating factor receptor | chr1 | GO:0046165 | Not Cancer Driver | No | 42 | 0.123 | 0 | 0 | 0.0 | 0 |
| PTS | PTS | Q03393 | 6-pyruvoyl tetrahydrobiopterin synthase | chr11 | GO:0046165 | Not Cancer Driver | No | 9 | 0.062 | 22 | 1 | 0.045 | 24 |
| QDPR | QDPR | P09417 | Dihydropteridine reductase | chr4 | GO:0046165 | Not Cancer Driver | No | 41 | 0.168 | 25 | 3 | 0.12 | 16 |
| SC5D_ENST00000392789 | SC5D | O75845 | Lathosterol oxidase | chr11 | GO:0046165 | Not Cancer Driver | No | 43 | 0.144 | 21 | 3 | 0.143 | 3 |
| SPHK1_ENST00000545180 | SPHK1 | Q9NYA1 | Sphingosine kinase 1 | chr17 | GO:0046165 | Not Cancer Driver | No | 47 | 0.122 | 25 | 2 | 0.08 | 0 |
| SPHK2 | SPHK2 | Q9NRA0 | Sphingosine kinase 2 | chr19 | GO:0046165 | Not Cancer Driver | No | 82 | 0.125 | 293 | 39 | 0.133 | 0 |
| SPR | SPR | P35270 | Sepiapterin reductase | chr2 | GO:0046165 | Not Cancer Driver | No | 23 | 0.088 | 19 | 4 | 0.211 | 2 |
| SPTLC1 | SPTLC1 | O15269 | Serine palmitoyltransferase 1 | chr9 | GO:0046165 | Not Cancer Driver | No | 50 | 0.106 | 27 | 5 | 0.185 | 5 |
| SPTLC2 | SPTLC2 | O15270 | Serine palmitoyltransferase 2 | chr14 | GO:0046165 | Not Cancer Driver | No | 72 | 0.128 | 9 | 2 | 0.222 | 5 |
| SPTLC3 | SPTLC3 | Q9NUV7 | Serine palmitoyltransferase 3 | chr20 | GO:0046165 | Not Cancer Driver | No | 135 | 0.245 | 40 | 12 | 0.3 | 0 |
| SPTSSA | SPTSSA | Q969W0 | Serine palmitoyltransferase small subunit A | chr14 | GO:0046165 | Not Cancer Driver | No | 9 | 0.127 | 0 | 0 | 0.0 | 0 |
| SPTSSB_ENST00000620149 | SPTSSB | Q8NFR3 | Serine palmitoyltransferase small subunit B | chr3 | GO:0046165 | Not Cancer Driver | No | 15 | 0.197 | 0 | 0 | 0.0 | 0 |
| SRD5A3 | SRD5A3 | Q9H8P0 | Polyprenol reductase | chr4 | GO:0046165 | Not Cancer Driver | No | 35 | 0.11 | 0 | 0 | 0.0 | 0 |